234:
198:) founded the Bijvoet Centre for Biomolecular Research as a joint research institute on March 25, 1988. The goal was to create a centre for research and expertise in structural biology with an internationally recognized academic staff and an advanced instrumental and computational infrastructure, with the original task to "conduct research into the molecular structure and reactivity of chemically and biologically important, medium-sized molecules and new methods to analyze them".
224:
Originally, the institute consisted of four groups focussing on different aspects of biomolecular research: NMR Spectroscopy, Crystal- and
Structural Chemistry, Biomembranes and Modelsystems and Bio-organic Chemistry of Glycoconjugates. Since that time, the institute has evolved and diversified and,
244:
The general theme of the research in the
Bijvoet Centre is understanding how biomolecules function in the human body and in life in general and how the processes and interactions between biomolecules in living cells are affected in patients. This includes, for example, research to understand the
316:
The
Bijvoet Centre hosts a large number of both Dutch and foreign PhD, master and bachelor level students with backgrounds in Chemistry, Pharmacy, Biology, Biomedical Sciences and related fields. All research groups provide education and research training programs for master level and PhD level
348:
The
Bijvoet Centre has leading infrastructures in protein mass spectrometry, electron microscopy, high-resolution NMR spectroscopy and X-ray crystallography to analyze the structure of biomolecules and the centre participates in the European
361:, and in 2012 the institute received funding to continue their efforts in proteomics as part of the Dutch National Roadmap for Research Infrastructures. Among the extensive NMR facilities available at the institute is also a unique
287:
The institute also has technological expertise that allows for the development of novel technology to study biomolecules, like the analysis of proteins inside cells using NMR spectroscopy, novel methods for the high-throughput,
392:
and the Dutch public-private partnership COAST for the analytical sciences. On
November 5, 2015, Dutch state secretary Sander Dekker officially opened the new national NMR facility at the Bijvoet Centre.
671:
166:, which play a role in biological processes such as regulation, interaction and recognition. The Bijvoet Centre houses advanced infrastructures for the analysis of proteins and other biomolecules using
804:
304:. The centre also works on the simulation of the interactions between proteins and their interaction with drugs. To be able to predict the effect these molecules have on each other's structure,
209:) for new equipment that would contribute to societally important areas such as pharmacochemistry and biotechnology. Among the first technology to be added to the institute, was equipment for
368:-NMR spectrometer. In 2012 the institute acquired funding to obtain one of the world's first 1.2 GHz NMR spectrometers, as part of the uNMR-NL project, coordinated by prof.
1014:
405:
to scientists with an outstanding contribution to furthering the fields of biomolecular chemistry and/or structural biology. Previous recipients of the
Bijvoet Medal include
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1230:
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195:
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103:
1220:
961:
318:
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217:) for animal studies. The official opening of the institute was on October 27, 1989, on occasion of which a symposium was organized, with Nobel prize winner
790:
376:(NWO) with 18.5M Euro, to establish a national infrastructure for ultra-high field NMR spectroscopy, a joined initiative between Utrecht University, the
381:
210:
241:
The
Bijvoet Centre has a staff of around 150 people, including about 10 full professors, 20 senior researchers, 50 postdocs and 50 PhD students.
827:
362:
194:
Utrecht
University and the Netherlands Foundation for Chemical Research (SON, which later became the Chemical Sciences division of NWO, the
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students and, since 1992, the educational programme for PhD students of the
Bijvoet Centre has been accredited by the
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377:
301:
214:
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565:
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437:
Since the
Bijvoet Centre was founded, the following people have served as scientific director of the institute:
297:
46:
1040:"Utrecht coordinates collaboration in life sciences: 32 million euro for two large-scale research facilities"
962:"Utrecht coordinates collaboration in life sciences: 32 million euro for two large-scale research facilities"
893:
422:
333:
293:
183:
262:
237:
The Hugo R. Kruytbuilding at Utrecht University houses part of the research groups of the Bijvoet Centre.
171:
442:
448:
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976:"Bruker Announces Installation of 527 GHz Solid State DNP-NMR Spectrometer at University of Utrecht"
329:
175:
472:
155:
151:
699:
353:
project Instruct for integrated structural biology. Since 2005, the research group of prof. dr.
478:
426:
385:
179:
300:, of a new mass spectrometer that allows the analysis of intact protein complexes, including
466:
418:
354:
253:
when it is mutated due to a genetic defect. Another example is the development of so-called
350:
520:
246:
1093:
535:
Karin Bos (October 31, 1989). "'Bijvoet Centrum voor Biomoleculair Onderzoek' geopend".
870:
406:
337:
305:
218:
805:"Unieke toekenning Innovative Doctoral Programme voor Nederlands onderzoek naar eiwit"
1214:
845:
410:
325:
281:
202:
596:"In the Spotlight: Bijvoet Center for Biomolecular Research at Utrecht University"
328:
in Europe to receive the prestigious Innovative Doctoral Programme grant from the
454:
369:
277:
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595:
289:
975:
727:
Frank van Geel (December 10, 2011). "Nieuwe NMR ziet ook gevouwen eiwitten".
118:
105:
460:
273:
156:
research on the relation between the structure and function of biomolecules
672:"Winnaar Spinozapremie 2010: Piet Gros, biomacromoleculair kristallograaf"
518:
b.k. (April 1988). "'Bijvoet-centrum voor moleculair Onderzoek' geopend".
269:
to target chemotherapeutics directly to cancer cells in a cancer patient.
742:
Marysa van den Berg (June 23, 2012). "Moeilijk te vangen fosforgroepen".
258:
159:
692:"NWO Spinoza Prize for Psychologist, Astronomer, Chemist And Classicist"
163:
1205:
225:
as of 2013, consist of seven research groups at Utrecht University.
138:
266:
232:
1147:"Friedrich Forster new scientific director of the Bijvoet Centre"
850:
MERIL - Mapping of the European Research Infrastructure Landscape
1161:"Alexandre Bonvin new scientific director of the Bijvoet Centre"
1079:"Staatssecretaris Dekker opent ultrasterke 'MRI' voor moleculen"
948:"32 miljoen euro voor twee grootschalige onderzoeksfaciliteiten"
206:
1015:"18.5 miljoen euro voor grootschalige NMR onderzoeksfaciliteit"
503:
Joop Kessels (April 7, 1988). "SON en RUU in Bijvoet Centrum".
272:
Two previous scientific directors of the institute, prof. dr.
245:
cause and potential therapeutic approaches for a disease like
167:
927:"Miljoenen voor supermagneet en eiwit-onderzoek in De Uithof"
1017:(in Dutch). Leiden University. 19 March 2012. Archived from
1182:"Marc Baldus new scientific director of the Bijvoet Center"
846:"Bijvoet Center - Bijvoet Center for Biomolecular Research"
615:"Bijvoet Centrum (1): ziektes bestrijden op atomair niveau"
324:
In 2012, the Bijvoet Centre was the first institute in the
994:"18.5 million euro for large-scale NMR research facility"
907:"Albert Heck zet Utrechts eiwit-onderzoek op de kaart".
634:"Bijvoet Centrum (2): Een medicijn voor taaislijmziekte"
554:(in Dutch). Vol. 85, no. 30/31. July 27, 1989.
201:
When the institute was founded, it received 8.5 million
182:. The institute is named after famous Dutch chemist
1081:(in Dutch). Universiteit Utrecht. November 6, 2015.
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79:
71:
63:
55:
45:
37:
29:
21:
1061:"Staatssecretaris Dekker opent uNMR-NL-faciliteit"
714:"Eiwit-onderzoeker Albert Heck wint Spinozapremie"
793:. Royal Netherlands Academy of Arts and Sciences.
777:"Bijvoet Centrum deelt succesformule op internet"
653:"Bijvoet Centrum (3): Met lama's kanker te lijf"
374:Netherlands Organisation for Scientific Research
196:Netherlands Organisation for Scientific Research
296:and the development, together with the company
249:, which is caused by misfolding of the protein
950:(in Dutch). Utrecht University. March 2, 2012.
920:
918:
590:
588:
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319:Royal Netherlands Academy of Arts and Sciences
942:
940:
811:(in Dutch). November 12, 2012. Archived from
758:"Unravelling complex biomolecular structures"
498:
496:
494:
8:
16:
828:"Flinke subsidie voor Universiteit Utrecht"
213:studies (which nowadays is mainly known as
1128:. Bijvoet Centre for Biomolecular Research
1092:Ainsworth, Susan J. (September 24, 2012).
15:
826:Martijn van Noppen (September 18, 2012).
1067:(in Dutch). nieuws.nl. November 4, 2015.
894:"Structural biologists share their toys"
148:Bijvoet Centre for Biomolecular Research
17:Bijvoet Centre for Biomolecular Research
1231:Research institutes established in 1988
490:
25:Discovering the Molecular Basis of Life
1221:Research institutes in the Netherlands
1163:. Utrecht University. 9 September 2019
670:Martijn van Calmthout (June 7, 2010).
425:as well as former scientific director
996:. Wageningen University. 2 March 2012
308:has been used for these simulations.
75:Padualaan 8, Utrecht, The Netherlands
7:
892:Callaway, Ewen (February 28, 2012).
330:Marie Curie Initial Training Network
186:, who worked at Utrecht University.
925:Xander Bronkhorst (March 2, 2012).
1184:. Utrecht University. 6 April 2016
651:Erik Hardeman (November 1, 2012).
632:Erik Hardeman (October 31, 2012).
613:Erik Hardeman (October 30, 2012).
390:Eindhoven University of Technology
284:, in 2010 and 2017, respectively.
14:
357:in the centre is the host of the
1098:Chemical & Engineering News
744:Chemisch2Weekblad Life Sciences
716:(in Dutch). NOS. June 17, 2017.
911:(in Dutch). February 10, 2005.
698:. June 7, 2010. Archived from
401:The Bijvoet Centre awards the
154:. The Bijvoet Centre performs
1:
1206:Website of the Bijvoet Centre
791:"Accredited research schools"
359:Netherlands Proteomics Centre
280:, both have received the NWO
566:"Bijvoet Centre - Research"
378:Radboud University Nijmegen
205:(approximately 3.9 million
150:is a research institute at
41:prof. dr. Friedrich Förster
1247:
775:Henk Klomp (May 6, 2013).
221:giving a keynote lecture.
1106:American Chemical Society
139:www.uu.nl/science/bijvoet
298:Thermo Fisher Scientific
261:fragments, based on the
964:. Instruct. March 2012.
832:Nationale Onderwijsgids
696:www.sciencenewsline.com
334:7th Framework Programme
294:protein phosphorylation
263:single-chain antibodies
184:Johannes Martin Bijvoet
302:therapeutic antibodies
238:
1149:. Utrecht University.
871:"Bijvoet Centre - UU"
382:Wageningen University
236:
172:X-ray crystallography
764:. November 30, 2012.
433:Scientific Directors
415:Nicolaas Bloembergen
550:"Bijvoet Centrum".
537:Utrechts Nieuwsblad
176:electron microscopy
115: /
38:Scientific Director
18:
1226:Utrecht University
372:and funded by the
292:based analysis of
257:, which are small
239:
152:Utrecht University
119:52.0855°N 5.1692°E
84:Utrecht University
1065:utrecht.nieuws.nl
982:. March 21, 2013.
815:on June 15, 2013.
729:Chemisch2Weekblad
702:on June 15, 2013.
552:Chemisch Weekblad
505:Chemische Courant
479:Hans Vliegenthart
447:2019-2023 :
443:Friedrich Förster
427:Hans Vliegenthart
386:Leiden University
332:programme of the
180:mass spectrometry
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449:Alexandre Bonvin
441:2023-now :
355:Albert J.R. Heck
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67:~10 M€ per annum
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1126:"Bijvoet Medal"
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1094:"Ivano Bertini"
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1021:on 9 April 2016
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124:52.0855; 5.1692
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423:Ivano Bertini
420:
419:Kurt Wüthrich
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411:Matthias Mann
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403:Bijvoet Medal
397:Bijvoet Medal
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1186:. Retrieved
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1019:the original
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600:EUROSCHOLARS
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933:(in Dutch).
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680:(in Dutch).
659:(in Dutch).
640:(in Dutch).
621:(in Dutch).
575:January 29,
539:(in Dutch).
524:(in Dutch).
507:(in Dutch).
477:1988-2000:
473:Rob Kaptein
471:2000-2006:
465:2006-2011:
459:2012-2016:
455:Marc Baldus
453:2016-2019:
370:Marc Baldus
363:solid state
278:Albert Heck
255:nanobullets
211:in vivo NMR
122: /
98:Coordinates
30:Established
1215:Categories
1188:2019-10-03
1167:2019-10-03
1132:2020-01-29
1111:2023-08-09
1046:2016-03-18
1042:. Instruct
1025:2016-03-18
1000:2016-03-18
873:. Instruct
677:Volkskrant
485:References
344:Facilities
290:proteomics
107:52°05′08″N
896:. Nature.
570:www.uu.nl
461:Piet Gros
312:Education
274:Piet Gros
265:found in
110:5°10′09″E
980:Azom.com
259:antibody
229:Research
160:proteins
80:Location
336:of the
190:History
135:Website
88:Utrecht
72:Address
47:Faculty
1104:(39).
877:Sep 4,
855:Sep 4,
267:llamas
164:lipids
64:Budget
909:Ublad
351:ESFRI
56:Staff
22:Motto
879:2019
857:2019
577:2020
251:CFTR
207:Euro
178:and
162:and
146:The
59:~150
33:1988
931:DUB
657:DUB
638:DUB
619:DUB
366:DNP
215:MRI
168:NMR
51:~30
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
