253:
230:
127:
152:
259:
158:
856:
inducible genes but is itself not interferon inducible. The gene is 1,327 bases in length and encodes a protein of 132 amino acids with a predicted molecular weight of 14378 daltons. Expression in adults is bone specific and highest in
1102:
1007:
Hanagata N, Li X (2011). "Osteoblast-enriched membrane protein IFITM5 regulates the association of CD9 with an FKBP11-CD81-FPRP complex and stimulates expression of interferon-induced genes".
266:
165:
1042:
Semler O, Garbes L, Keupp K, Swan D, Zimmermann K, Becker J, Iden S, Wirth B, Eysel P, Koerber F, Schoenau E, Bohlander SK, Wollnik B, Netzer C (August 2012).
1044:"A mutation in the 5'-UTR of IFITM5 creates an in-frame start codon and causes autosomal-dominant osteogenesis imperfecta type V with hyperplastic callus"
559:
578:
88:
971:
1097:
989:
252:
785:
229:
778:
958:
937:
151:
126:
954:
933:
68:
17:
1107:
265:
164:
258:
157:
1112:
623:
76:
909:
604:
897:
140:
55:
740:
693:
100:
761:
714:
1073:
1024:
48:
1063:
1055:
1016:
345:
276:
220:
175:
96:
840:
is a gene that encodes a membrane protein thought to play a role in bone mineralization.
320:
1068:
1043:
1091:
849:
80:
881:
338:
117:
104:
994:
National Center for
Biotechnology Information, U.S. National Library of Medicine
976:
National Center for
Biotechnology Information, U.S. National Library of Medicine
59:, interferon induced transmembrane protein 5, BRIL, DSPA1, Hrmp1, OI5, fragilis4
1059:
1020:
421:
858:
853:
237:
134:
84:
523:
481:
359:
304:
291:
203:
190:
92:
1077:
1028:
825:
820:
809:
668:
649:
635:
590:
885:
869:
868:
is located on chromosome 7. A homolog is also known to be present in
793:
545:
865:
72:
896:
The protein has two transmembrane domains. It associates with
848:
The gene is located on the short arm of the Crick strand of
884:
and its bone specific expression appears to be limited to
328:
18:
Bone-restricted interferon-induced transmembrane protein
493:
754:
733:
707:
686:
1103:Abnormalities of dermal fibrous and elastic tissue
950:
948:
946:
929:
927:
925:
275:
174:
27:Protein-coding gene in the species Homo sapiens
955:GRCm38: Ensembl release 89: ENSMUSG00000025489
8:
934:GRCh38: Ensembl release 89: ENSG00000206013
852:(11p15.5). It is located with a cluster of
908:Mutations in the gene are associated with
838:Interferon-induced transmembrane protein 5
519:
316:
215:
112:
1067:
921:
29:
280:
241:
236:
179:
138:
133:
7:
1048:American Journal of Human Genetics
751:
730:
704:
683:
659:
640:
614:
595:
569:
550:
498:
416:
354:
333:
25:
264:
257:
251:
228:
163:
156:
150:
125:
482:More reference expression data
406:olfactory zone of nasal mucosa
1:
249:
148:
1098:Genes on human chromosome 11
880:The gene first appeared in
1129:
1060:10.1016/j.ajhg.2012.06.011
1021:10.1016/j.bbrc.2011.04.136
1009:Biochem Biophys Res Commun
990:"Mouse PubMed Reference:"
972:"Human PubMed Reference:"
824:
819:
815:
808:
792:
786:Chr 7: 140.53 – 140.53 Mb
773:
758:
737:
726:
711:
690:
679:
666:
662:
647:
643:
634:
621:
617:
602:
598:
589:
576:
572:
557:
553:
544:
529:
522:
518:
506:
501:
492:
479:
428:
419:
366:
357:
327:
319:
315:
298:
285:
248:
227:
218:
214:
197:
184:
147:
124:
115:
111:
66:
63:
53:
46:
41:
37:
32:
910:osteogenesis imperfecta
402:upper lobe of left lung
898:FK506 binding protein
398:right coronary artery
141:Chromosome 11 (human)
779:Chr 11: 0.3 – 0.3 Mb
243:Chromosome 7 (mouse)
864:The homolog in the
1108:Skeletal disorders
624:ENSMUSG00000025489
105:IFITM5 - orthologs
835:
834:
831:
830:
804:
803:
769:
768:
748:
747:
722:
721:
701:
700:
675:
674:
656:
655:
630:
629:
611:
610:
585:
584:
566:
565:
514:
513:
510:
509:
488:
487:
475:
474:
413:
412:
311:
310:
210:
209:
16:(Redirected from
1120:
1113:Collagen disease
1082:
1081:
1071:
1039:
1033:
1032:
1004:
998:
997:
986:
980:
979:
968:
962:
952:
941:
931:
817:
816:
788:
781:
764:
752:
743:
731:
727:RefSeq (protein)
717:
705:
696:
684:
660:
641:
615:
596:
570:
551:
520:
499:
484:
424:
422:Top expressed in
417:
370:body of pancreas
362:
360:Top expressed in
355:
334:
317:
307:
294:
283:
268:
261:
255:
244:
232:
216:
206:
193:
182:
167:
160:
154:
143:
129:
113:
107:
58:
51:
30:
21:
1128:
1127:
1123:
1122:
1121:
1119:
1118:
1117:
1088:
1087:
1086:
1085:
1041:
1040:
1036:
1006:
1005:
1001:
988:
987:
983:
970:
969:
965:
953:
944:
932:
923:
918:
906:
894:
886:therian mammals
878:
846:
826:View/Edit Mouse
821:View/Edit Human
784:
777:
774:Location (UCSC)
760:
739:
713:
692:
605:ENSG00000206013
480:
471:
466:
462:
458:
454:
450:
446:
442:
438:
434:
420:
409:
404:
400:
396:
392:
388:
384:
380:
376:
372:
358:
302:
289:
281:
271:
270:
269:
262:
242:
219:Gene location (
201:
188:
180:
170:
169:
168:
161:
139:
116:Gene location (
67:
54:
47:
28:
23:
22:
15:
12:
11:
5:
1126:
1124:
1116:
1115:
1110:
1105:
1100:
1090:
1089:
1084:
1083:
1034:
1015:(3): 378–384.
999:
981:
963:
942:
920:
919:
917:
914:
905:
902:
893:
890:
877:
874:
845:
842:
833:
832:
829:
828:
823:
813:
812:
806:
805:
802:
801:
799:
797:
790:
789:
782:
775:
771:
770:
767:
766:
756:
755:
749:
746:
745:
735:
734:
728:
724:
723:
720:
719:
709:
708:
702:
699:
698:
688:
687:
681:
677:
676:
673:
672:
664:
663:
657:
654:
653:
645:
644:
638:
632:
631:
628:
627:
619:
618:
612:
609:
608:
600:
599:
593:
587:
586:
583:
582:
574:
573:
567:
564:
563:
555:
554:
548:
542:
541:
536:
531:
527:
526:
516:
515:
512:
511:
508:
507:
504:
503:
496:
490:
489:
486:
485:
477:
476:
473:
472:
470:
469:
465:
461:
457:
453:
449:
445:
441:
437:
433:
429:
426:
425:
414:
411:
410:
408:
407:
403:
399:
395:
391:
390:gastric mucosa
387:
383:
379:
375:
371:
367:
364:
363:
351:
350:
342:
331:
325:
324:
321:RNA expression
313:
312:
309:
308:
300:
296:
295:
287:
284:
279:
273:
272:
263:
256:
250:
246:
245:
240:
234:
233:
225:
224:
212:
211:
208:
207:
199:
195:
194:
186:
183:
178:
172:
171:
162:
155:
149:
145:
144:
137:
131:
130:
122:
121:
109:
108:
65:
61:
60:
52:
44:
43:
39:
38:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
1125:
1114:
1111:
1109:
1106:
1104:
1101:
1099:
1096:
1095:
1093:
1079:
1075:
1070:
1065:
1061:
1057:
1054:(2): 349–57.
1053:
1049:
1045:
1038:
1035:
1030:
1026:
1022:
1018:
1014:
1010:
1003:
1000:
995:
991:
985:
982:
977:
973:
967:
964:
960:
956:
951:
949:
947:
943:
939:
935:
930:
928:
926:
922:
915:
913:
911:
903:
901:
899:
891:
889:
887:
883:
875:
873:
871:
867:
862:
860:
855:
851:
850:chromosome 11
843:
841:
839:
827:
822:
818:
814:
811:
807:
800:
798:
795:
791:
787:
783:
780:
776:
772:
765:
763:
757:
753:
750:
744:
742:
736:
732:
729:
725:
718:
716:
710:
706:
703:
697:
695:
689:
685:
682:
680:RefSeq (mRNA)
678:
671:
670:
665:
661:
658:
652:
651:
646:
642:
639:
637:
633:
626:
625:
620:
616:
613:
607:
606:
601:
597:
594:
592:
588:
581:
580:
575:
571:
568:
562:
561:
556:
552:
549:
547:
543:
540:
537:
535:
532:
528:
525:
521:
517:
505:
500:
497:
495:
491:
483:
478:
467:
463:
459:
455:
451:
447:
443:
439:
436:body of femur
435:
431:
430:
427:
423:
418:
415:
405:
401:
397:
393:
389:
385:
381:
377:
373:
369:
368:
365:
361:
356:
353:
352:
349:
347:
343:
341:
340:
336:
335:
332:
330:
326:
322:
318:
314:
306:
301:
297:
293:
288:
278:
274:
267:
260:
254:
247:
239:
235:
231:
226:
222:
217:
213:
205:
200:
196:
192:
187:
177:
173:
166:
159:
153:
146:
142:
136:
132:
128:
123:
119:
114:
110:
106:
102:
98:
94:
90:
86:
82:
78:
74:
70:
62:
57:
50:
45:
40:
36:
31:
19:
1051:
1047:
1037:
1012:
1008:
1002:
993:
984:
975:
966:
907:
895:
892:Biochemistry
879:
863:
847:
837:
836:
759:
741:NP_001020466
738:
712:
694:NM_001025295
691:
667:
648:
622:
603:
577:
558:
538:
533:
344:
337:
303:140,530,204
290:140,528,871
64:External IDs
859:osteoblasts
452:granulocyte
386:bone marrow
374:granulocyte
282:7|7 F5
42:Identifiers
1092:Categories
961:, May 2017
940:, May 2017
916:References
854:interferon
394:right lung
348:(ortholog)
85:HomoloGene
882:bony fish
876:Evolution
762:NP_444318
715:NM_053088
524:Orthologs
93:GeneCards
1078:22863195
1029:21600883
957:–
936:–
912:type 5.
904:Clinical
844:Genomics
810:Wikidata
432:calvaria
202:299,526
189:298,200
1069:3415541
959:Ensembl
938:Ensembl
870:lizards
636:UniProt
591:Ensembl
530:Species
464:condyle
323:pattern
181:11p15.5
81:1934923
49:Aliases
1076:
1066:
1027:
796:search
794:PubMed
669:O88728
650:A6NNB3
560:387733
546:Entrez
494:BioGPS
468:morula
460:embryo
456:embryo
97:IFITM5
73:614757
56:IFITM5
33:IFITM5
866:mouse
579:73835
539:Mouse
534:Human
448:ankle
444:fossa
440:molar
382:gonad
378:blood
346:Mouse
339:Human
286:Start
221:Mouse
185:Start
118:Human
89:14210
1074:PMID
1025:PMID
900:11.
861:.
329:Bgee
277:Band
238:Chr.
176:Band
135:Chr.
69:OMIM
1064:PMC
1056:doi
1017:doi
1013:409
502:n/a
299:End
198:End
101:OMA
77:MGI
1094::
1072:.
1062:.
1052:91
1050:.
1046:.
1023:.
1011:.
992:.
974:.
945:^
924:^
888:.
872:.
305:bp
292:bp
204:bp
191:bp
99:;
95::
91:;
87::
83:;
79::
75:;
71::
1080:.
1058::
1031:.
1019::
996:.
978:.
223:)
120:)
103::
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
