612:
589:
2427:
965:
42:
2455:
850:(FDA) issued a communication warning of the possibility of severe and sometimes incapacitating bone, joint or muscle pain. A study conducted by the American Society of Bone and Mineral Research concluded that long-term use of
1443:
135:
190:
1360:
742:
835:. At the study's conclusion, both doses significantly reduced the occurrence risk of new vertebral fractures by 50–52 percent when compared to the effects of the placebo drug.
2485:
1436:
1334:
1257:"Information for Healthcare Professionals: Bisphosphonates (marketed as Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax+D, Reclast, Skelid, and Zometa)"
2364:
2490:
1429:
64:
698:
101:
684:
1832:
2357:
838:
Ibandronate is efficacious for the prevention of metastasis-related bone fractures in multiple myeloma, breast cancer, and certain other cancers.
1327:
2495:
1278:
Shane E, Burr D, Ebeling PR, Abrahamsen B, Adler RA, Brown TD, et al. (American
Society for Bone and Mineral Research) (November 2010).
1256:
1213:
Sittig HB (2012). "Pathogenesis and bisphosphonate treatment of skeletal events and bone pain in metastatic cancer: focus on ibandronate".
1280:"Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research"
1025:
Ibandronic acid is sold under the brand names Boniva, Bondronat, Bonviva, Bandrone, Ibandrix, Adronil, Bondrova, Bonprove, and
Fosfonat.
2500:
1974:
1747:
1649:
1367:
2371:
1401:
1172:
1012:
718:
131:
2378:
986:
1338:
811:(FDA) approved ibandronate as a daily treatment for post-menopausal osteoporosis. The basis for this approval was a three-year,
2395:
2304:
330:
220:
82:
854:, including Boniva, may increase the risk of a rare but serious fracture of the femur. The drug also has been associated with
118:
2350:
990:
1712:
2445:
1554:
847:
808:
807:
Ibandronate is indicated for the treatment and prevention of osteoporosis in post-menopausal women. In May 2003, the US
452:
1892:
812:
568:
975:
1546:
779:
994:
979:
2069:
96:
726:
InChI=1S/C9H23NO7P2/c1-3-4-5-7-10(2)8-6-9(11,18(12,13)14)19(15,16)17/h11H,3-8H2,1-2H3,(H2,12,13,14)(H2,15,16,17)
2480:
2406:
2299:
2073:
1956:
1842:
1742:
855:
1852:
401:
1837:
1587:
172:
607:
2123:
1912:
1882:
275:
2400:
1827:
1321:
392:
1122:"Ibandronate: the first once-monthly oral bisphosphonate for treatment of postmenopausal osteoporosis"
529:
1752:
297:
1797:
796:
584:
347:
183:
179:
1597:
1309:
1238:
770:
and metastasis-associated skeletal fractures in people with cancer. It may also be used to treat
146:
550:
2156:
1705:
1652:
1407:
1397:
1301:
1230:
1168:
1162:
1143:
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540:
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235:
54:
1421:
2430:
2255:
2143:
1291:
1222:
1133:
1094:
1068:
827:
women with post-menopausal osteoporosis. Each participant also received daily oral doses of
786:
624:
356:
257:
461:
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2283:
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2240:
1762:
1559:
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938:
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287:
265:
74:
611:
588:
2319:
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2064:
1529:
1524:
1466:
1138:
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880:
824:
771:
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2469:
2314:
2235:
1902:
1897:
1802:
1657:
600:
1313:
2324:
2309:
2260:
2029:
1698:
1662:
1457:
1453:
1242:
816:
767:
203:
198:
17:
381:
2273:
2250:
1922:
1635:
1627:
1580:
964:
33:
2329:
2278:
2186:
2138:
1952:
1942:
1937:
1927:
1807:
1669:
1642:
1620:
1188:
660:
432:
41:
1411:
2412:
2196:
2176:
2133:
2128:
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2044:
2014:
1994:
1947:
1932:
1917:
1679:
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832:
310:
68:
1305:
1234:
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2118:
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2049:
2024:
2004:
1989:
1984:
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1474:
1337:. Journal of Bone and Mineral Research. 14 September 2010. Archived from
412:
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2151:
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2019:
1999:
1979:
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1817:
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828:
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775:
367:
1335:"JBMR Publishes ASBMR Task Force Report on Atypical Femoral Fractures"
1226:
2191:
2039:
2034:
2009:
1777:
1757:
1361:"Osteonecrosis of the jaw (ONJ) and drug treatments for osteoporosis"
1296:
1279:
783:
520:
315:
100:
1366:. United Kingdom: The National Osteoporosis Society. Archived from
489:
481:
1605:
1396:(Seventh ed.). New Delhi: Jaypee Brothers Medical Publisher.
683:
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556:
500:
2201:
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241:
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1967:
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766:medication used in the prevention and treatment of
672:
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48:
1193:The American Society of Health-System Pharmacists
380:
2365:GlaxoSmithKline Services Unlimited v Commission
355:
130:
1706:
1437:
8:
117:
32:
993:. Unsourced material may be challenged and
249:In general: ℞ (Prescription only)
2486:Farnesyl pyrophosphate synthase inhibitors
2218:
1872:
1865:
1732:
1713:
1699:
1691:
1444:
1430:
1422:
610:
587:
440:
40:
1295:
1137:
1126:Therapeutics and Clinical Risk Management
1013:Learn how and when to remove this message
858:, relatively rare but serious condition.
460:
865:
2450:
2358:Christopher v. SmithKline Beecham Corp.
1034:
723:
703:
583:
420:
335:
1319:
1167:. John Wiley & Sons. p. 523.
799:and approved for medical use in 1996.
601:
338:Hydroxy--1-phosphonopropyl]phosphinate
31:
1833:Recherche et Industrie Thérapeutiques
549:
528:
508:
73:
7:
2491:Drugs developed by Hoffmann-La Roche
1284:Journal of Bone and Mineral Research
991:adding citations to reliable sources
555:
202:
1748:GlaxoSmithKline Pharmaceuticals Ltd
1650:Parathyroid hormone-related protein
1259:. U.S. Food and Drug Administration
1120:Bauss F, Schimmer RC (March 2006).
706:O=P(O)(O)C(O)(CCN(CCCCC)C)P(=O)(O)O
488:
480:
371:
1394:Essentials of Medical Pharmacology
1326:: CS1 maint: overridden setting (
650:
59:Boniva, Bonviva, Bondronat, others
25:
2372:United States v. Glaxo Group Ltd.
1392:Tripathi KD (30 September 2013).
2453:
2426:
2425:
2379:United States v. GlaxoSmithKline
963:
641:
635:
2396:Drug Industry Documents Archive
1161:Fischer J, Ganellin CR (2006).
1099:European Medicines Agency (EMA)
1073:European Medicines Agency (EMA)
1047:European Medicines Agency (EMA)
731:Key:MPBVHIBUJCELCL-UHFFFAOYSA-N
2351:Canada v. GlaxoSmithKline Inc.
644:
629:
1:
1164:Analogue-based Drug Discovery
2496:Drugs developed by Genentech
848:Food and Drug Administration
809:Food and Drug Administration
1547:Bone morphogenetic proteins
795:It was patented in 1986 by
2517:
2501:Drugs developed by GSK plc
778:levels). It is typically
619:Chemical and physical data
2421:
1853:Smith, Kline & French
739:
714:
694:
326:
282:(concentration-dependent)
39:
1843:S. E. Massengill Company
1743:GlaxoSmithKline Pakistan
856:osteonecrosis of the jaw
1838:Reliant Pharmaceuticals
1588:Aluminium chlorohydrate
1452:Drugs for treatment of
1593:Dual action bone agent
2401:GlaxoSmithKline Prize
1828:Human Genome Sciences
1798:Allen & Hanburys
1753:Stiefel Laboratories
1576:Resorption inhibitor
987:improve this section
950:Society and culture
868:
797:Boehringer Mannheim
36:
18:Boniva (medication)
2305:Silas M. Burroughs
1848:SmithKline Beecham
1813:Burroughs Wellcome
1598:Strontium ranelate
1332:; Lay summary in:
1075:. 23 February 2004
866:
790:ibandronate sodium
136:Ibandronate_sodium
119:Ibandronate_sodium
2441:
2440:
2338:
2337:
2210:
2209:
2084:
2083:
1784:
1783:
1688:
1687:
1290:(11): 2267–2294.
1227:10.1159/000338947
1101:. 21 January 2011
1023:
1022:
1015:
947:
946:
875:Relative potency
867:Relative potency
757:
756:
685:Interactive image
569:CompTox Dashboard
245:
233:
161:
128:
111:
94:
27:Chemical compound
16:(Redirected from
2508:
2458:
2457:
2456:
2449:
2429:
2428:
2256:Patrick Vallance
2219:
1948:Wellbutrin/Zyban
1873:
1866:
1733:
1715:
1708:
1701:
1692:
1521:Non-nitrogenous
1446:
1439:
1432:
1423:
1416:
1415:
1389:
1383:
1382:
1380:
1378:
1372:
1365:
1357:
1351:
1350:
1348:
1346:
1331:
1325:
1317:
1299:
1297:10.1002/jbmr.253
1275:
1269:
1268:
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1253:
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1246:
1210:
1204:
1203:
1201:
1199:
1185:
1179:
1178:
1158:
1152:
1151:
1141:
1117:
1111:
1110:
1108:
1106:
1091:
1085:
1084:
1082:
1080:
1065:
1059:
1058:
1056:
1054:
1043:"Bondronat EPAR"
1039:
1018:
1011:
1007:
1004:
998:
967:
959:
869:
846:In 2008, the US
774:(elevated blood
753:
752:
745:
687:
667:
652:
646:
643:
637:
631:
614:
603:
592:
591:
577:
575:
559:
553:
532:
512:
492:
484:
464:
444:
424:
404:
384:
374:
373:
359:
301:
243:
240:
231:
228:
206:
159:
156:
138:
127:
124:
121:
110:
107:
104:
93:
90:
77:
44:
37:
35:
21:
2516:
2515:
2511:
2510:
2509:
2507:
2506:
2505:
2481:Bisphosphonates
2466:
2465:
2464:
2454:
2452:
2444:
2442:
2437:
2417:
2384:
2334:
2288:
2284:Laurie Glimcher
2251:Manvinder Banga
2246:Roy M. Anderson
2241:Simon Dingemans
2223:
2206:
2080:
1963:
1857:
1790:
1780:
1768:
1763:ViiV Healthcare
1724:
1719:
1689:
1684:
1564:
1560:Eptotermin alfa
1555:Dibotermin alfa
1541:
1535:Tiludronic acid
1515:Zoledronic acid
1510:Risedronic acid
1505:Pamidronic acid
1500:Neridronic acid
1495:Minodronic acid
1490:Incadronic acid
1485:Ibandronic acid
1480:Alendronic acid
1467:Bisphosphonates
1461:
1450:
1420:
1419:
1404:
1391:
1390:
1386:
1376:
1374:
1373:on 17 June 2017
1370:
1363:
1359:
1358:
1354:
1344:
1342:
1341:on 9 April 2016
1333:
1318:
1277:
1276:
1272:
1262:
1260:
1255:
1254:
1250:
1212:
1211:
1207:
1197:
1195:
1187:
1186:
1182:
1175:
1160:
1159:
1155:
1119:
1118:
1114:
1104:
1102:
1093:
1092:
1088:
1078:
1076:
1067:
1066:
1062:
1052:
1050:
1041:
1040:
1036:
1031:
1019:
1008:
1002:
999:
984:
968:
957:
952:
872:Bisphosphonate
864:
852:bisphosphonates
844:
842:Adverse effects
831:and 400IUs of
805:
760:Ibandronic acid
748:
746:
743:(what is this?)
740:
735:
732:
727:
722:
721:
710:
707:
702:
701:
690:
665:
655:
649:
640:
634:
595:
571:
563:
535:
515:
495:
467:
447:
427:
407:
387:
370:
362:
342:
339:
334:
333:
299:
281:
276:Protein binding
266:Bioavailability
258:Pharmacokinetic
252:
210:
174:
167:
148:
141:
34:Ibandronic acid
28:
23:
22:
15:
12:
11:
5:
2514:
2512:
2504:
2503:
2498:
2493:
2488:
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2467:
2463:
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2439:
2438:
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2435:
2422:
2419:
2418:
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2415:
2410:
2403:
2398:
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2390:
2386:
2385:
2383:
2382:
2375:
2368:
2361:
2354:
2346:
2344:
2340:
2339:
2336:
2335:
2333:
2332:
2327:
2322:
2320:Henry Wellcome
2317:
2312:
2307:
2302:
2300:Thomas Beecham
2296:
2294:
2290:
2289:
2287:
2286:
2281:
2276:
2271:
2268:
2266:Lynn Elsenhans
2263:
2258:
2253:
2248:
2243:
2238:
2233:
2231:Philip Hampton
2227:
2225:
2216:
2212:
2211:
2208:
2207:
2205:
2204:
2199:
2194:
2189:
2184:
2179:
2174:
2169:
2164:
2159:
2157:Goody's Powder
2154:
2149:
2146:
2141:
2136:
2131:
2126:
2121:
2116:
2111:
2106:
2101:
2098:
2092:
2090:
2086:
2085:
2082:
2081:
2079:
2078:
2067:
2062:
2057:
2052:
2047:
2042:
2037:
2032:
2027:
2022:
2017:
2012:
2007:
2002:
1997:
1992:
1987:
1982:
1977:
1971:
1969:
1965:
1964:
1962:
1961:
1950:
1945:
1940:
1935:
1930:
1925:
1920:
1915:
1910:
1905:
1900:
1895:
1890:
1885:
1879:
1877:
1870:
1863:
1859:
1858:
1856:
1855:
1850:
1845:
1840:
1835:
1830:
1825:
1823:Glaxo Wellcome
1820:
1815:
1810:
1805:
1800:
1794:
1792:
1786:
1785:
1782:
1781:
1776:
1774:
1770:
1769:
1767:
1766:
1760:
1755:
1750:
1745:
1739:
1737:
1730:
1726:
1725:
1720:
1718:
1717:
1710:
1703:
1695:
1686:
1685:
1683:
1682:
1677:
1672:
1667:
1666:
1665:
1660:
1647:
1646:
1645:
1632:
1631:
1630:
1617:
1616:
1615:
1602:
1601:
1600:
1590:
1585:
1584:
1583:
1572:
1570:
1566:
1565:
1563:
1562:
1557:
1551:
1549:
1543:
1542:
1540:
1539:
1538:
1537:
1532:
1530:Clodronic acid
1527:
1525:Etidronic acid
1519:
1518:
1517:
1512:
1507:
1502:
1497:
1492:
1487:
1482:
1471:
1469:
1463:
1462:
1451:
1449:
1448:
1441:
1434:
1426:
1418:
1417:
1402:
1384:
1352:
1270:
1248:
1205:
1180:
1173:
1153:
1112:
1095:"Iasibon EPAR"
1086:
1069:"Bonviva EPAR"
1060:
1049:. 25 June 1996
1033:
1032:
1030:
1027:
1021:
1020:
971:
969:
962:
956:
953:
951:
948:
945:
944:
941:
935:
934:
931:
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913:
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903:
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896:
893:
887:
886:
883:
877:
876:
873:
863:
860:
843:
840:
804:
801:
764:bisphosphonate
755:
754:
737:
736:
734:
733:
730:
728:
725:
717:
716:
715:
712:
711:
709:
708:
705:
697:
696:
695:
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691:
689:
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678:
670:
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627:
621:
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615:
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564:
562:
561:
545:
543:
537:
536:
534:
533:
525:
523:
517:
516:
514:
513:
505:
503:
497:
496:
494:
493:
487:as salt:
485:
477:
475:
469:
468:
466:
465:
457:
455:
449:
448:
446:
445:
437:
435:
429:
428:
426:
425:
417:
415:
409:
408:
406:
405:
397:
395:
389:
388:
386:
385:
377:
375:
364:
363:
361:
360:
352:
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344:
343:
341:
340:
337:
329:
328:
327:
324:
323:
319:
318:
313:
307:
306:
305:10 to 60 hours
303:
294:
293:
290:
284:
283:
278:
272:
271:
268:
262:
261:
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253:
251:
250:
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177:
175:administration
169:
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140:
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122:
105:
87:
85:
79:
78:
71:
61:
60:
57:
51:
50:
46:
45:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2513:
2502:
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2484:
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2473:
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2433:
2424:
2423:
2420:
2414:
2411:
2409:
2408:
2404:
2402:
2399:
2397:
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2393:
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2387:
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2376:
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2369:
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2359:
2355:
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2352:
2348:
2347:
2345:
2341:
2331:
2328:
2326:
2323:
2321:
2318:
2316:
2315:John K. Smith
2313:
2311:
2308:
2306:
2303:
2301:
2298:
2297:
2295:
2291:
2285:
2282:
2280:
2277:
2275:
2272:
2270:Jesse Goodman
2269:
2267:
2264:
2262:
2259:
2257:
2254:
2252:
2249:
2247:
2244:
2242:
2239:
2237:
2236:Emma Walmsley
2234:
2232:
2229:
2228:
2226:
2220:
2217:
2213:
2203:
2200:
2198:
2195:
2193:
2190:
2188:
2185:
2183:
2180:
2178:
2175:
2173:
2170:
2168:
2165:
2163:
2160:
2158:
2155:
2153:
2150:
2147:
2145:
2142:
2140:
2137:
2135:
2132:
2130:
2127:
2125:
2122:
2120:
2117:
2115:
2112:
2110:
2107:
2105:
2102:
2099:
2097:
2094:
2093:
2091:
2087:
2077:
2076:
2071:
2068:
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2063:
2061:
2058:
2056:
2053:
2051:
2048:
2046:
2043:
2041:
2038:
2036:
2033:
2031:
2028:
2026:
2023:
2021:
2018:
2016:
2013:
2011:
2008:
2006:
2003:
2001:
1998:
1996:
1993:
1991:
1988:
1986:
1983:
1981:
1978:
1976:
1973:
1972:
1970:
1966:
1960:
1959:
1954:
1951:
1949:
1946:
1944:
1941:
1939:
1936:
1934:
1931:
1929:
1928:Paxil/Seroxat
1926:
1924:
1921:
1919:
1916:
1914:
1911:
1909:
1906:
1904:
1901:
1899:
1896:
1894:
1891:
1889:
1886:
1884:
1881:
1880:
1878:
1874:
1871:
1867:
1864:
1860:
1854:
1851:
1849:
1846:
1844:
1841:
1839:
1836:
1834:
1831:
1829:
1826:
1824:
1821:
1819:
1816:
1814:
1811:
1809:
1806:
1804:
1803:Beecham Group
1801:
1799:
1796:
1795:
1793:
1789:Predecessors,
1787:
1779:
1775:
1771:
1764:
1761:
1759:
1756:
1754:
1751:
1749:
1746:
1744:
1741:
1740:
1738:
1734:
1731:
1727:
1723:
1716:
1711:
1709:
1704:
1702:
1697:
1696:
1693:
1681:
1678:
1676:
1673:
1671:
1668:
1664:
1661:
1659:
1658:Abaloparatide
1656:
1655:
1654:
1651:
1648:
1644:
1641:
1640:
1639:
1637:
1633:
1629:
1626:
1625:
1624:
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1614:
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1609:
1607:
1603:
1599:
1596:
1595:
1594:
1591:
1589:
1586:
1582:
1579:
1578:
1577:
1574:
1573:
1571:
1567:
1561:
1558:
1556:
1553:
1552:
1550:
1548:
1544:
1536:
1533:
1531:
1528:
1526:
1523:
1522:
1520:
1516:
1513:
1511:
1508:
1506:
1503:
1501:
1498:
1496:
1493:
1491:
1488:
1486:
1483:
1481:
1478:
1477:
1476:
1473:
1472:
1470:
1468:
1464:
1459:
1455:
1454:bone diseases
1447:
1442:
1440:
1435:
1433:
1428:
1427:
1424:
1413:
1409:
1405:
1403:9789350259375
1399:
1395:
1388:
1385:
1369:
1362:
1356:
1353:
1340:
1336:
1329:
1323:
1315:
1311:
1307:
1303:
1298:
1293:
1289:
1285:
1281:
1274:
1271:
1258:
1252:
1249:
1244:
1240:
1236:
1232:
1228:
1224:
1220:
1216:
1209:
1206:
1194:
1190:
1184:
1181:
1176:
1174:9783527607495
1170:
1166:
1165:
1157:
1154:
1149:
1145:
1140:
1135:
1131:
1127:
1123:
1116:
1113:
1100:
1096:
1090:
1087:
1074:
1070:
1064:
1061:
1048:
1044:
1038:
1035:
1028:
1026:
1017:
1014:
1006:
996:
992:
988:
982:
981:
977:
972:This section
970:
966:
961:
960:
954:
949:
942:
940:
937:
936:
932:
930:
927:
926:
922:
919:
918:
914:
912:
909:
908:
904:
902:
899:
898:
894:
892:
889:
888:
884:
882:
879:
878:
874:
871:
870:
861:
859:
857:
853:
849:
841:
839:
836:
834:
830:
826:
822:
818:
814:
810:
802:
800:
798:
793:
791:
788:
785:
781:
777:
773:
772:hypercalcemia
769:
765:
761:
751:
744:
738:
729:
724:
720:
713:
704:
700:
693:
686:
682:
681:
679:
676:
671:
664:
662:
658:
628:
626:
622:
617:
613:
609:
606:
604:
602:ECHA InfoCard
598:
590:
586:
585:DTXSID5048340
582:
581:
579:
570:
566:
558:
557:RCSB PDB
552:
547:
546:
544:
542:
538:
531:
527:
526:
524:
522:
518:
511:
507:
506:
504:
502:
498:
491:
486:
483:
479:
478:
476:
474:
470:
463:
459:
458:
456:
454:
450:
443:
439:
438:
436:
434:
430:
423:
419:
418:
416:
414:
410:
403:
399:
398:
396:
394:
390:
383:
379:
378:
376:
369:
365:
358:
354:
353:
351:
349:
345:
336:
332:
325:
320:
317:
314:
312:
308:
304:
302:
295:
291:
289:
285:
280:90.9 to 99.5%
279:
277:
273:
269:
267:
263:
259:
255:
248:
246: Rx-only
239:
237:
227:
226:
224:
222:
218:
213:
205:
200:
197:
196:
194:
192:
188:
185:
181:
178:
176:
170:
164:
155:
154:
152:
150:
144:
137:
133:
123:
120:
115:
106:
103:
98:
89:
88:
86:
84:
80:
76:
72:
70:
66:
62:
58:
56:
52:
49:Clinical data
47:
43:
38:
30:
19:
2431:
2407:Side Effects
2405:
2377:
2370:
2363:
2356:
2349:
2325:Andrew Witty
2310:Mahlon Kline
2261:Vivienne Cox
2074:
2030:H5N1 vaccine
1957:
1907:
1791:acquisitions
1729:Subsidiaries
1663:Teriparatide
1634:
1619:
1604:
1592:
1575:
1484:
1393:
1387:
1375:. Retrieved
1368:the original
1355:
1343:. Retrieved
1339:the original
1322:cite journal
1287:
1283:
1273:
1261:. Retrieved
1251:
1221:(6): 380–7.
1218:
1214:
1208:
1196:. Retrieved
1192:
1183:
1163:
1156:
1129:
1125:
1115:
1103:. Retrieved
1098:
1089:
1077:. Retrieved
1072:
1063:
1051:. Retrieved
1046:
1037:
1024:
1009:
1000:
985:Please help
973:
920:Ibandronate
862:Pharmacology
845:
837:
823:-controlled
817:double-blind
806:
803:Medical uses
794:
789:
768:osteoporosis
759:
758:
747:
741:
298:Elimination
221:Legal status
215:Legal status
83:License data
29:
2274:Judy Lewent
1636:Cathepsin K
1628:Romosozumab
1581:Ipriflavone
1475:Nitrogenous
1132:(1): 3–18.
1003:August 2024
955:Brand names
939:Zoledronate
929:Risedronate
911:Alendronate
901:Pamidronate
891:Tiludronate
668: g·mol
608:100.214.537
510:CHEBI:93770
357:114084-78-5
322:Identifiers
184:intravenous
55:Trade names
2470:Categories
2343:Litigation
2330:Chris Gent
2279:Urs Rohner
2187:Parodontax
1995:Engerix-B
1808:Block Drug
1670:Calcitonin
1643:Odanacatib
1621:Sclerostin
1345:27 October
1263:27 October
1029:References
881:Etidronate
813:randomized
780:formulated
673:3D model (
661:Molar mass
541:PDB ligand
462:UMD7G2653W
433:ChemSpider
393:IUPHAR/BPS
348:CAS Number
331:IUPAC name
288:Metabolism
2413:Study 329
2224:Directors
2222:Board of
2197:Sensodyne
2177:Nicorette
2134:Emergen-C
2129:ChapStick
2109:BC Powder
2104:Aquafresh
2045:Pandemrix
2015:Hepatyrix
1913:Flixonase
1893:Augmentin
1680:Vitamin D
1653:analogues
1638:inhibitor
1623:inhibitor
1613:Denosumab
1608:inhibitor
1412:868299888
1377:14 August
1215:Onkologie
1105:30 August
1079:28 August
1053:28 August
974:does not
923:500-1000
833:vitamin D
530:ChEMBL997
311:Excretion
300:half-life
173:Routes of
147:Pregnancy
75:Monograph
69:Drugs.com
2460:Medicine
2432:Category
2182:NiQuitin
2172:Nicoderm
2167:Lucozade
2162:Horlicks
2144:Excedrin
2119:Caltrate
2065:Shingrix
2055:Rabavert
2050:Pediarix
2025:Infanrix
2005:FluLaval
1990:Cervarix
1985:Boostrix
1968:Vaccines
1943:Ventolin
1933:Serlipet
1923:Lamictal
1918:Hycamtin
1903:Beconase
1862:Products
1314:15194275
1306:20842676
1235:22722461
1189:"Boniva"
1148:18360577
915:100-500
750:(verify)
413:DrugBank
191:ATC code
180:By mouth
162: B3
149:category
114:DailyMed
2152:Geritol
2148:Flonase
2124:Centrum
2114:Biotene
2096:Actifed
2070:Twinrix
2060:Rotarix
2020:Hiberix
2000:Fluarix
1980:Bexsero
1938:Tagamet
1898:Avandia
1869:Current
1736:Current
1675:Calcium
1243:8413102
1198:3 April
1139:1661644
995:removed
980:sources
829:calcium
821:placebo
782:as its
776:calcium
666:319.231
625:Formula
422:DB00710
368:PubChem
207:)
201: (
199:M05BA06
134::
116::
99::
2476:Amines
2446:Portal
2215:People
2192:Ribena
2089:Former
2040:Menveo
2035:Kinrix
2010:Havrix
1975:Arexvy
1953:Zantac
1908:Boniva
1883:Advair
1876:Pharma
1778:Haleon
1773:Former
1758:Tesaro
1410:
1400:
1312:
1304:
1241:
1233:
1171:
1146:
1136:
784:sodium
699:SMILES
521:ChEMBL
490:D04486
482:D08056
316:Kidney
236:℞-only
234:
129:
112:
102:by INN
95:
2389:Other
2293:Other
2100:Advil
1818:Glaxo
1765:(85%)
1606:RANKL
1569:Other
1371:(PDF)
1364:(PDF)
1310:S2CID
1239:S2CID
943:5000
933:1000
825:trial
762:is a
719:InChI
675:JSmol
548:BFQ (
501:ChEBI
442:54839
382:60852
2202:Tums
2075:more
1958:more
1888:Alli
1408:OCLC
1398:ISBN
1379:2018
1347:2010
1328:link
1302:PMID
1265:2010
1231:PMID
1200:2011
1169:ISBN
1144:PMID
1107:2024
1081:2024
1055:2024
978:any
976:cite
905:100
787:salt
551:PDBe
473:KEGG
453:UNII
402:3059
270:0.6%
260:data
65:AHFS
2139:Eno
1722:GSK
1458:M05
1292:doi
1223:doi
1134:PMC
989:by
895:10
574:EPA
372:CID
292:Nil
204:WHO
132:FDA
97:EMA
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1955:…
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1320:{{
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