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93:, frequently, about 9 out of 10 sections are discarded. Thus, only 10% of the surgical margin is examined. If the whole "ribbon" was mounted, it would take an inordinate number of glass slides, and not be feasible.
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Kimjai-Asadi A, et al. Dermatol Surg. 2007 Dec;33(12):1434-9; discussion 1439-41. Margin involvement after the excision of melanoma in situ: the need for complete en face examination of the surgical margins.
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Bread loafing false negative error rate can be reduced by "cutting through the block". Basically, the entire surgical specimen is sliced, and mounted. Even though this method will approach
47:. The process involves cutting the specimen into 3 or more sections. The cut sections are mounted by embedding in paraffin or frozen medium. The cut edge is then thinly sliced with a
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is decreased. For this reason, it is not used near the eyelids, and in other cosmetically important areas of the body.
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Common eyelid malignancies: Clinical features and management options
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method of tissue processing. The error rate is reduced when the
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is a common method of processing surgical specimens for
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is increased, and the error rate is increased when the
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20:Pictogram of margin controlled histology or CCPDMA
58:This method is used to determine the negative
28:Pictogram of standard bread loafing histology
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126:Basal Cell and Squamous Cell Skin Cancers.
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130:National Comprehensive Cancer Network
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109:Fong, Kenneth., Malhotra, Raman.
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