355:
31:
1424:
Druker, Brian J.; Guilhot, François; O'Brien, Stephen G.; Gathmann, Insa; Kantarjian, Hagop; Gattermann, Norbert; Deininger, Michael W.N.; Silver, Richard T.; Goldman, John M.; Stone, Richard M.; Cervantes, Francisco; Hochhaus, Andreas; Powell, Bayard L.; Gabrilove, Janice L.; Rousselot, Philippe
1020:
O'Brien, Stephen G.; Guilhot, François; Larson, Richard A.; Gathmann, Insa; Baccarani, Michele; Cervantes, Francisco; Cornelissen, Jan J.; Fischer, Thomas; Hochhaus, Andreas; Hughes, Timothy; Lechner, Klaus; Nielsen, Johan L.; Rousselot, Philippe; Reiffers, Josy; Saglio, Giuseppe (2003-03-13).
2150:
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approval of the drug in record time. This work changed the life expectancy of patients with CML from an average of 3 to 5 years to a 89% five-year survival, and has resulted in a paradigm-shift in cancer treatment from non-specific
3154:
3184:
1130:
2151:"Knight Cancer Institute at Oregon Health & Science University director named winner of Watanabe Prize, will deliver keynote address at virtual 2020 Indiana CTSI Annual Meeting"
3164:
3199:
3169:
555:
663:
1676:
968:
Druker, B. J.; Talpaz, M.; Resta, D. J.; Peng, B.; Buchdunger, E.; Ford, J. M.; Lydon, N. B.; Kantarjian, H.; Capdeville, R.; Ohno-Jones, S.; Sawyers, C. L. (2001-04-05).
1577:"The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: from the perspective of a large group of CML experts"
295:
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magazine, and the couple have three children (as of 2009). An earlier marriage, to
Barbara Rodriguez in 1990, ended in divorce in 1999.
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Druker, B. J.; Tamura, S.; Buchdunger, E.; Ohno, S.; Segal, G. M.; Fanning, S.; Zimmermann, J.; Lydon, N. B. (May 1996).
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1911:
1023:"Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia"
715:
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484:
303:
145:
728:
Hamdan Award for
Medical Research Excellence, Sheikh Hamdan Bin Rashid Al Maktoum Awards for Medical Sciences (2014).
639:
110:
479:
In 2015, Druker celebrated the completion of the Knight Cancer
Challenge, raising $ 1 billion for research at the
3039:
2545:
2257:
1766:
760:
August M. Watanabe Prize in
Translational Research, Indiana Clinical and Translational Sciences Institute (2020)
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270:
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2004:
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1294:"The Miracle Worker: Dr. Brian Druker Fires a Magic Bullet That May Eliminate a Lethal Form of Leukemia"
970:"Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia"
436:
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912:"Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells"
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223:
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593:
Charles
Rodolphe Brupbacher Prize for Cancer Research, Charles Rodolphe Brupbacher Stiftung (2001)
2743:
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103:
2078:"Prof. Brian J Druker - Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences - HMA"
1602:"OHSU sets fundraising record by meeting $ 1 billion challenge from Nike co-founder and wife"
2914:
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1550:"Top Oregon Health & Science University researcher to doctors: Rise up over drug prices"
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319:
307:
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1979:
518:), is a joint effort by medical centers, drug makers and the Food and Drug Administration.
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459:) and then spearheaded the highly successful clinical trials of imatinib, which led to
487:
and more than 10,000 donors from Oregon and beyond matched a $ 500 million grant from
354:
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and investigating the optimal use of these molecularly targeted agents. He performed
269:), the first medication that specifically targets cancer cells, for the treatment of
138:
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1237:
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Druker also helped lead a national clinical trial to find effective treatments for
465:
2029:
1427:"Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia"
3080:
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731:
711:
A. Alfred
Taubman Prize for Excellence in Translational Medical Science (2013)
417:
158:
1626:"Bringing Precision Medicine to AML Patients | Leukemia and Lymphoma Society"
1526:
1452:
1086:
1048:
995:
935:
2569:
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2406:
2203:
Brian Druker
Seminars: "Imatinib as a Paradigm of Targeted Cancer Therapies"
1742:
323:
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1056:
1003:
911:
943:
255:
30:
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1426:
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1022:
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444:
412:
In May 2007, he became director of the OHSU Cancer
Institute—renamed the
390:
266:
262:
251:
247:
243:
476:, but has been publicly critical of the drug's high price for patients.
2815:
1677:"CLINICAL SCIENTIST AWARDS IN TRANSLATIONAL RESEARCH: Grant Recipients"
1517:
1500:
927:
691:
in
Healthcare and Medical Technology, The Japan Prize Foundation (2012)
676:
Stanley J. Korsmeyer Award, American
Society for Clinical Investigation
473:
291:, setting the stage for future discoveries in the quest to end cancer.
85:
1475:"CML Patients Approach Normal Life Expectancy With Imatinib Treatment"
672:
for Cancer Research, Meyenburg Foundation, Heidelberg, Germany (2009)
386:
334:. He completed his internship and residency in internal medicine at
310:, among others. He has been called "Oregon's best-known scientist".
657:
1861:"Keio Medical Science Prize｜KEIO UNIVERSITY MEDICAL SCIENCE FUND"
431:
Druker's research is focused on translating the knowledge of the
212:
https://www.ohsu.edu/knight-cancer-institute/meet-dr-brian-druker
3190:
Recipients of the Lasker–DeBakey Clinical Medical Research Award
740:
in the Field of Medicine, Prince Mahidol Award Foundation (2019)
2819:
2211:
472:. Druker has been widely recognized for his work in developing
153:
Sheikh Hamdan bin Rashid Al Maktoum Award for Medical Sciences
1839:"Golden Plate Awardees of the American Academy of Achievement"
1401:"OHSU Knight Cancer Institute announces leadership transition"
1160:"2009 Winners: Lasker~DeBakey Clinical Medical Research Award"
802:"Meyenburg Award 2009 for the First Targeted Anti-Cancer Drug"
775:
Druker is married to Alexandra Hardy, a one-time reporter for
734:
in Biopharmaceutical Science, The Tang Prize Foundation (2018)
349:
1183:
1107:"TIME Magazine Cover: Drugs That Fight Cancer - May 28, 2001"
491:. The challenge gave the institute the funding to launch the
1939:
https://www.dicksonprize.pitt.edu/recipients/2012-druker.php
1695:"Brupbacher Prize – Charles Rodolphe Brupbacher Foundation"
582:. Druker has received the following awards, among others:
424:. In March 2024, he became chief executive officer of the
3155:
Members of the United States National Academy of Sciences
1886:"OHSU's Druker recognized for pioneering cancer research"
1238:"Targeted treatment of cancer receives the Sjöberg Prize"
1347:"Five to receive honorary degrees at 149th Commencement"
860:"Meet Dr. Brian Druker | Knight Cancer Institute | OHSU"
416:
in October 2008 following a $ 100 million donation from
366:
1791:"OHSU researcher to get American Cancer Society medal"
3185:
Fellows of the American Academy of Arts and Sciences
2054:"Honorary Doctorates | Erasmus University Rotterdam"
599:-Richard and Hinda Rosenthal Foundation Award (2001)
3105:
Dejusticia: The Center for Law, Justice and Society
3073:
3020:
2907:
2854:
2736:
2597:
2462:
2327:
2246:
1743:"Prize Recipients | Warren Alpert Foundation Prize"
1373:"OHSU Cancer Institute gets $ 100 million donation"
556:
American Association for the Advancement of Science
281:approval in record time and landed on the cover of
207:
189:
181:
91:
81:
67:
59:
37:
21:
306:in Medicine and Biomedical Research, and the 2019
629:, Robert Koch Foundation, Cologne, Germany (2005)
538:(formerly Institute of Medicine) in 2003 and the
2005:"OncLive Announces 2013 "Giants of Cancer Care""
1131:"OHSU marks 20 years of life-saving cancer drug"
1723:American Association for Cancer Research (AACR)
493:Cancer Early Detection Advanced Research Center
302:in Healthcare and Medical Technology, the 2013
3165:Oregon Health & Science University faculty
1287:
1285:
1263:"How OHSU's Brian Druker Hopes to Cure Cancer"
664:Lasker-DeBakey Clinical Medical Research Award
296:Lasker-DeBakey Clinical Medical Research Award
238:. He is the chief executive officer of OHSU's
2831:
2223:
1912:"Ernest Beutler Lecture and Prize Recipients"
1341:
1339:
8:
3099:Bangladesh Environmental Lawyers Association
2034:A. Alfred Taubman Medical Research Institute
287:magazine. Druker’s work launched the era of
3200:Members of the National Academy of Medicine
884:"Brian J. Druker M.D. | OHSU People | OHSU"
796:
794:
544:American Society for Clinical Investigation
534:) from 2002 to 2019. He was elected to the
428:and Dr. Thomas A. Sellers became director.
3170:University of California, San Diego alumni
2838:
2824:
2816:
2230:
2216:
2208:
2131:Luau & Legends of Surfing Invitational
1653:"Tang Prize | Laureates | Brian J. Druker"
766:, Stanford Drug Discovery Symposium (2023)
718:in Medicine and Biomedical Research (2013)
666:, Albert and Mary Lasker Foundation (2009)
29:
18:
1516:
1442:
1038:
985:
649:European Inventor of the Year, Industry,
646:Medical Science Fund, Tokyo, Japan (2007)
836:. Portland, Oregon. pp. A1, A12–A13
572:American Association for Cancer Research
340:Washington University School of Medicine
76:Washington University School of Medicine
790:
401:from 1984 to 1987. He began working at
1961:
1950:
703:University of California San Francisco
403:Oregon Health & Science University
228:Oregon Health & Science University
198:Oregon Health & Science University
1884:Williams, Elisa (February 22, 2011).
1647:
1645:
1232:
1230:
1205:
1203:
1178:
1176:
1153:
1151:
708:Giants of Cancer Care, OncLive (2013)
580:The American Society for Cell Biology
568:American Society of Clinical Oncology
552:American Academy of Arts and Sciences
7:
2127:"Rell Sunn 2019 - Druker and Hunter"
1699:Charles Rodolphe Brupbacher Stiftung
1271:. Portland, Oregon. January 16, 2014
1075:"Researcher Behind the Drug Gleevec"
1068:
1066:
1015:
1013:
963:
961:
905:
903:
854:
852:
850:
3180:Howard Hughes Medical Investigators
1767:"William Dameshek Prize Recipients"
1292:Charles, Nick (February 19, 2001).
1027:The New England Journal of Medicine
974:The New England Journal of Medicine
826:Terry, Lynne (December 20, 2015) .
332:University of California, San Diego
72:University of California, San Diego
1371:Dworkin, Andy (October 29, 2008).
1351:Washington University in St. Louis
828:"OHSU's $ 1 billion war on cancer"
681:Ernest Beutler Lecture and Prize,
548:Association of American Physicians
14:
2179:Stanford Cardiovascular Institute
748:Royal Swedish Academy of Sciences
564:American Society for Microbiology
3195:Physicians from Portland, Oregon
2175:"2023 Drug Discovery Conference"
1548:Budnick, Nick (April 25, 2013).
1501:"First person: Brian Druker, MD"
353:
342:in St. Louis from 1981 to 1984.
294:He is the recipient of the 2009
2657:/ John Frederick Grassle (2013)
2106:Prince Mahidol Award Foundation
1847:American Academy of Achievement
1431:New England Journal of Medicine
1073:Dreifus, Claudia (2009-11-02).
542:in 2007. He is a member of the
528:Howard Hughes Medical Institute
512:Leukemia & Lymphoma Society
443:that led to the development of
194:Howard Hughes Medical Institute
1324:Commencement Archive 2014-2019
683:American Society of Hematology
614:American Society of Hematology
603:Warren Alpert Foundation Prize
586:Translational Research Award,
560:American Society of Hematology
526:Druker was an investigator of
1:
2367:Ernest John Christopher Polge
1499:Printz, Carrie (2017-05-15).
806:German Cancer Research Center
757:at UC San Diego Health (2019)
258:, and professor of medicine.
250:Research, Associate Dean for
1184:"The Japan Prize Foundation"
723:Erasmus University Rotterdam
658:International CML Foundation
540:National Academy of Sciences
536:National Academy of Medicine
395:Dana–Farber Cancer Institute
16:American physician-scientist
2900:(Jordan, USA, Saudi Arabia)
2102:"Professor Brian J. Druker"
1819:www.robert-koch-stiftung.de
987:10.1056/NEJM200104053441401
716:Albany Medical Center Prize
694:Dickson Prize in Medicine,
470:targeted therapeutic agents
304:Albany Medical Center Prize
277:). In 2001, Gleevec gained
222:(born April 30, 1955) is a
146:Albany Medical Center Prize
3216:
1242:Kungl. Vetenskapsakademien
1188:The Japan Prize Foundation
764:Lifetime Achievement Award
640:Keio Medical Science Prize
111:Keio Medical Science Prize
2908:Biopharmaceutical Science
2383:William Hayward Pickering
2258:Ephraim Katchalski-Katzir
1936:www.dicksonprize.pitt.edu
1795:Portland Business Journal
698:School of Medicine (2012)
576:Children’s Oncology Group
289:precision cancer medicine
203:
174:
28:
1984:Office of the Chancellor
1215:Albany Med Health System
696:University of Pittsburgh
453:chronic myeloid leukemia
271:chronic myeloid leukemia
2880:Veerabhadran Ramanathan
2855:Sustainable Development
2524:/ Keith J. Sainsbury /
1681:Burroughs Wellcome Fund
621:American Cancer Society
588:Burroughs Wellcome Fund
508:Beat AML clinical trial
481:Knight Cancer Institute
426:Knight Cancer Institute
414:Knight Cancer Institute
318:Druker earned both his
256:OHSU School of Medicine
240:Knight Cancer Institute
3150:American hematologists
2927:Emmanuelle Charpentier
2695:Emmanuelle Charpentier
2314:Frank Sherwood Rowland
1865:www.ms-fund.keio.ac.jp
651:European Patent Office
634:Academy of Achievement
607:Harvard Medical School
522:Memberships and awards
500:acute myeloid leukemia
433:molecular pathogenesis
399:Harvard Medical School
261:Druker helped develop
2862:Gro Harlem Brundtland
1719:"Brian J. Druker, MD"
489:Phil and Penny Knight
346:Teaching and Research
220:Brian J. Druker, M.D.
125:Lasker Clinical Award
23:Brian J. Druker, M.D.
3160:American oncologists
3034:Wm. Theodore de Bary
2963:Charles A. Dinarello
2800:John Michael Wallace
1444:10.1056/NEJMoa062867
1040:10.1056/NEJMoa022457
755:Moores Cancer Center
738:Prince Mahidol Award
721:Honorary Doctorate,
632:Golden Plate Award,
612:Dameshek Prize, The
2975:Tadamitsu Kishimoto
2868:Arthur H. Rosenfeld
2784:/ Kazuo Hagimoto /
2623:Tadamitsu Kishimoto
2353:Jacques-Louis Lions
1843:www.achievement.org
1815:"Robert Koch Award"
1581:ashpublications.org
1162:. Lasker Foundation
510:, sponsored by the
441:preclinical studies
224:physician-scientist
97:Novartis-Drew Award
54:St. Paul, Minnesota
2762:Robert A. Weinberg
2744:Robert G. Gallager
2689:Steven D. Tanksley
2675:Theodore Friedmann
2578:Victor A. McKusick
2536:Masatoshi Takeichi
2484:Timothy R. Parsons
2480:John B. Goodenough
2474:Kimishige Ishizaka
2449:Jack L. Strominger
2445:W. Wesley Peterson
2425:Hiroyuki Yoshikawa
2421:Joseph Engelberger
2397:Edward F. Knipling
2082:www.hmaward.org.ae
1916:www.hematology.org
1771:www.hematology.org
1657:www.tang-prize.org
1558:. Portland, Oregon
1518:10.1002/cncr.30753
1381:. Portland, Oregon
1211:"The Albany Prize"
1079:The New York Times
928:10.1038/nm0596-561
808:. October 12, 2009
656:The Rowley Prize,
485:Oregon Legislature
437:specific therapies
365:. You can help by
3132:
3131:
2945:Anthony R. Hunter
2813:
2812:
2782:Masataka Nakazawa
2776:Christopher Field
2661:Yasuharu Suematsu
2605:Shun-ichi Iwasaki
2564:Peter Shaw Ashton
2504:Benoit Mandelbrot
2498:Andrzej Tarkowski
2318:Elias James Corey
1960:Missing or empty
1511:(10): 1683–1684.
1437:(23): 2408–2417.
1349:(Press release).
1320:"Brian J. Druker"
1158:Strauss, Evelyn.
980:(14): 1031–1037.
753:Rell Sunn Award,
627:Robert-Koch Prize
383:
382:
217:
216:
176:Scientific career
166:The Sjöberg Prize
150:
143:
108:
104:Robert Koch Prize
3207:
3111:The Legal Agenda
2971:(Australia, USA)
2915:James P. Allison
2840:
2833:
2826:
2817:
2651:C. Grant Willson
2439:Marc Van Montagu
2413:Takashi Sugimura
2347:Xavier Le Pichon
2292:Donald Henderson
2288:Georges Vendryes
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1033:(11): 994–1004.
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798:
619:Medal of Honor,
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357:
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330:degree from the
236:Portland, Oregon
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3117:Cheryl Saunders
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3046:Yoshinobu Shiba
3016:
3011:Jens Juul Holst
3005:Svetlana Mojsov
2999:Joel F. Habener
2957:John Mendelsohn
2933:Jennifer Doudna
2903:
2850:
2844:
2814:
2809:
2804:Ronald M. Evans
2790:Karl Deisseroth
2786:Gero Miesenböck
2758:Bert Vogelstein
2754:Martin A. Green
2732:
2713:Max Dale Cooper
2699:Jennifer Doudna
2671:Yutaka Takahasi
2593:
2540:Erkki Ruoslahti
2522:Akira Fujishima
2490:Tim Berners-Lee
2458:
2453:Don Craig Wiley
2339:W. Jason Morgan
2323:
2282:Theodore Maiman
2268:Willem J. Kolff
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2030:"Taubman Prize"
2028:
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2014:
2012:
2003:
2002:
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1399:Gibbs, Amanda.
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916:Nature Medicine
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773:
689:The Japan Prize
670:Meyenburg Award
644:Keio University
524:
435:of cancer into
379:
373:
370:
363:needs expansion
348:
336:Barnes Hospital
316:
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68:Alma mater
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3083:(South Africa)
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3061:
3058:Jessica Rawson
3055:
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3022:
3018:
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2989:(Hungary, USA)
2987:Katalin KarikĂł
2984:
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2768:Katalin KarikĂł
2765:
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2734:
2733:
2731:
2730:
2723:Yoshio Okamoto
2720:
2717:Jacques Miller
2706:
2692:
2682:
2668:
2665:C. David Allis
2658:
2648:
2641:Nicholas Lydon
2630:
2619:Dennis Ritchie
2612:
2609:Peter Vitousek
2601:
2599:
2595:
2594:
2592:
2591:
2584:Dennis Meadows
2581:
2574:Robert E. Kahn
2567:
2560:Peter GrĂĽnberg
2553:
2543:
2529:
2526:John H. Lawton
2515:
2508:James A. Yorke
2501:
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2377:Kary B. Mullis
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2311:
2304:Luc Montagnier
2285:
2274:Henry Beachell
2271:
2264:David Turnbull
2261:
2254:John R. Pierce
2250:
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2197:External links
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1583:. May 30, 2013
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1479:Cancer Network
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1425:(2006-12-07).
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361:This section
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77:
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50:(age 69)
40:
36:
32:
27:
20:
3101:(Bangladesh)
3095:(UK, Israel)
3040:Stephen Owen
3028:Yu Ying-shih
2951:Brian Druker
2950:
2921:Tasuku Honjo
2886:Jane Goodall
2874:James Hansen
2748:Svante Pääbo
2685:Hideo Hosono
2655:Jean Fréchet
2637:Brian Druker
2636:
2633:Janet Rowley
2615:Ken Thompson
2532:Makoto Nagao
2494:Anne McLaren
2435:Jozef Schell
2363:Gerhard Ertl
2357:John J. Wild
2343:Dan McKenzie
2308:Robert Gallo
2300:Frank Fenner
2278:Gurdev Khush
2183:. Retrieved
2178:
2169:
2158:. Retrieved
2155:Indiana CTSI
2154:
2145:
2134:. Retrieved
2130:
2121:
2110:. Retrieved
2108:. 2019-11-23
2105:
2096:
2085:. Retrieved
2081:
2072:
2061:. Retrieved
2057:
2048:
2037:. Retrieved
2033:
2024:
2013:. Retrieved
2011:. 2013-07-26
2008:
1999:
1987:. Retrieved
1983:
1980:"UCSF Medal"
1974:
1962:|title=
1942:. Retrieved
1935:
1930:
1919:. Retrieved
1915:
1906:
1895:. Retrieved
1889:
1879:
1868:. Retrieved
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1722:
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1483:. Retrieved
1481:. 2017-07-21
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1303:. Retrieved
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1273:. Retrieved
1266:
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1244:. 2019-02-04
1241:
1218:. Retrieved
1214:
1191:. Retrieved
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3119:(Australia)
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3074:Rule of Law
3064:Hsu Cho-yun
3054:(Australia)
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2373:Frank Press
2239:Japan Prize
2181:(in Samoan)
1630:www.lls.org
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298:, the 2012
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60:Nationality
3139:Categories
3107:(Colombia)
3093:Joseph Raz
2939:Feng Zhang
2847:Tang Prize
2727:Rattan Lal
2703:Adi Shamir
2550:Akira Endo
2470:Ian McHarg
2417:Bruce Ames
2296:Isao Arita
2241:recipients
2185:2023-10-13
2160:2023-10-13
2136:2023-10-13
2112:2023-10-13
2087:2023-10-13
2063:2023-10-13
2058:www.eur.nl
2039:2023-10-13
2015:2023-10-13
1944:2023-10-13
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1897:2015-12-27
1870:2023-10-13
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1562:2015-12-27
1485:2023-10-13
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1385:2015-12-27
1357:2015-12-27
1329:2023-10-13
1305:2015-12-27
1275:2015-12-27
1248:2023-10-13
1220:2023-10-13
1193:2023-10-13
1166:2015-12-27
1141:2023-10-13
1116:2023-10-13
1092:2023-10-13
893:2023-10-13
869:2023-10-13
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812:2015-12-27
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3113:(Lebanon)
3013:(Denmark)
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2407:Masao Ito
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314:Education
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3089:(Canada)
3021:Sinology
2995:(Canada)
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2864:(Norway)
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1535:28475244
1461:17151364
1111:TIME.com
1057:12637609
1004:11287972
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2882:(India)
2009:OncLive
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944:8616716
705:(2013).
506:). The
474:Gleevec
449:Gleevec
267:Gleevec
254:in the
208:Website
86:Gleevec
2806:(2024)
2792:(2023)
2778:(2022)
2764:(2021)
2750:(2020)
2729:(2019)
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948:S2CID
3060:(UK)
2888:(UK)
1991:2020
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1531:PMID
1523:ISSN
1457:PMID
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1083:ISSN
1053:PMID
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532:HHMI
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