234:
211:
108:
133:
893:
240:
139:
946:
974:
C19orf44 is shown to be expressed at low levels in various tissues throughout the body as shown by NCBI's EST Profile. It most highly expressed in the testis and ovary, but also has significant expression in the thyroid and parathyroid. C19orf44 is expressed in all stages of development, except for
845:) that is highly conserved throughout its orthologs. This protein is most highly expressed in the testis and ovary, but also has significant expression in the thyroid and parathyroid. Other names for this protein include: LOC84167.
841:. C19orf44 is an uncharacterized protein with an unknown function in humans. C19orf44 is non-limiting implying that the protein (and gene) exists in other species besides human. The protein contains one domain of unknown function (
1789:
Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE (September 2011). "A directed protein interaction network for investigating intracellular signal transduction".
247:
146:
995:
using
ClustalW provided evidence that the DUF in C19orf44 is highly conserved in its orthologs. The table below represents a small selection of the orthologs found using
930:
C19orf44 has experimentally determined phosphorylation sites at the S114 and S213 positions. Other predicted post-translational modifications were found using tools on
559:
540:
69:
1888:
1269:
1251:
949:
Cartoon image illustrating the C19orf44 protein and its predicted features. Image created using the DOG software from The CUCKOO WorkGroup.
233:
767:
1416:
1368:
774:
210:
1238:
1217:
1615:
Horton P, Nakai K (1997). "Better prediction of protein cellular localization sites with the k nearest neighbors classifier".
132:
107:
1234:
1213:
246:
145:
992:
239:
138:
842:
604:
57:
1645:
1369:"AceView: Gene:C19orf44, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView"
585:
1566:
Liu W, Xie Y, Ma J, Luo X, Nie P, Zuo Z, Lahrmann U, Zhao Q, Zheng Y, Zhao Y, Xue Y, Ren J (October 2015).
892:
996:
121:
1181:
874:
44:
725:
674:
991:
of C19orf44 have been found in most mammals and a select few other vertebrates and invertebrates.
1815:
1166:
988:
828:
81:
922:. Additionally, there is a domain of unknown function (DUF) located from amino acid 474 to 641.
750:
729:
699:
678:
1343:
1864:
1833:
Rolland T, TaΕan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, et al. (November 2014).
1807:
1624:
1597:
1443:
915:
77:
37:
1854:
1846:
1799:
1587:
1579:
1393:"Homo sapiens chromosome 19 open reading frame 44 (C19orf44), transcrip - Nucleotide - NCBI"
326:
257:
201:
156:
1317:"C19orf44 chromosome 19 open reading frame 44 [Homo sapiens (human)] - Gene - NCBI"
301:
918:
of 5.52. The amino acid sequence for C19orf44 was found to be serine rich using tools on
1859:
1834:
1592:
1567:
945:
911:
1882:
858:
1583:
1568:"IBS: an illustrator for the presentation and visualization of biological sequences"
1519:"uncharacterized protein C19orf44 isoform 1 [Homo sapiens] - Protein - NCBI"
61:
1819:
1518:
1392:
959:
939:
319:
98:
1617:
Proceedings. International
Conference on Intelligent Systems for Molecular Biology
85:
1274:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1256:
National Center for
Biotechnology Information, U.S. National Library of Medicine
975:
in infants. There is an increased expression of C19orf44 in a developing fetus.
935:
1850:
402:
1803:
886:
870:
862:
218:
115:
65:
1491:
1189:
854:
504:
462:
340:
285:
272:
184:
171:
73:
1868:
1811:
1693:
1601:
1765:
1669:
1628:
1316:
1287:
814:
809:
48:, chromosome 19 open reading frame 44, Chromosome 19 open reading frame 44
919:
798:
649:
630:
963:
834:
616:
571:
1467:
931:
782:
526:
1344:"Tissue expression of C19orf44 - Summary - The Human Protein Atlas"
1180:
C19orf44 has been found to interact with various proteins from the
1185:
944:
896:
Position of C19orf44 on chromosome 19. Image taken from GeneCards.
891:
1717:
866:
838:
1741:
1542:
309:
1835:"A proteome-scale map of the human interactome network"
474:
1543:"ExPASy: SIB Bioinformatics Resource Portal - Home"
743:
718:
692:
667:
1288:"Entrez Gene: Chromosome 19 open reading frame 44"
1230:
1228:
1226:
1209:
1207:
1205:
934:and are shown in the protein illustration below.
256:
155:
1718:"National Center for Biotechnology Information"
1235:GRCm38: Ensembl release 89: ENSMUSG00000052794
1184:method. Interactions with Hsp90 co-chaperone (
938:is predicted at S3. There is also a predicted
1492:"SAPS < Sequence Statistics < EMBL-EBI"
958:C19orf44 is predicted to be localized in the
8:
1367:Thierry-Mieg, Danielle; Thierry-Mieg, Jean.
1192:associated protein (SPERT) have been found.
1214:GRCh38: Ensembl release 89: ENSG00000105072
1694:"BLAST: Basic Local Alignment Search Tool"
837:that in humans is encoded by the C19orf44
500:
297:
196:
93:
1858:
1591:
1766:"Multiple Sequence Alignment - CLUSTALW"
1742:"TimeTree :: The Timescale of Life"
1670:"Multiple Sequence Alignment - CLUSTALW"
1000:
1201:
16:Mammalian protein found in Homo sapiens
885:C19orf44 is located on the nineteenth
18:
1640:
1638:
1513:
1511:
1438:
1436:
1338:
1336:
1311:
1309:
1307:
1305:
1303:
261:
222:
217:
160:
119:
114:
7:
942:motif from amino acid 212 to 221.
857:in length, and has an unprocessed
740:
715:
689:
664:
640:
621:
595:
576:
550:
531:
479:
397:
335:
314:
14:
926:Post-translational modifications
245:
238:
232:
209:
144:
137:
131:
106:
1002:C19orf44 Significant Orthologs
463:More reference expression data
1:
1584:10.1093/bioinformatics/btv362
1468:"ExPASy - Compute pI/Mw tool"
1417:"C19orf44 - Entry on Aceview"
1015:Accession Number (from NCBI)
230:
129:
1889:Genes on human chromosome 19
993:Multiple sequence alignments
1905:
1851:10.1016/j.cell.2014.10.050
865:in length. It contains 10
853:The entire gene is 25,416
1804:10.1126/scisignal.2001699
1646:"EST Profile - Hs.631627"
1270:"Mouse PubMed Reference:"
1252:"Human PubMed Reference:"
1031:Golden Snub-nosed Monkey
877:that exist for C19orf44.
813:
808:
804:
797:
781:
762:
747:
722:
711:
696:
671:
660:
647:
643:
628:
624:
615:
602:
598:
583:
579:
570:
557:
553:
538:
534:
525:
510:
503:
499:
487:
482:
473:
460:
409:
400:
347:
338:
308:
300:
296:
279:
266:
229:
208:
199:
195:
178:
165:
128:
105:
96:
92:
55:
52:
42:
35:
30:
26:
21:
1027:Rhinopithecus roxellana
437:Rostral migratory stream
1141:Mizuhopecten yessoensis
768:Chr 19: 16.5 β 16.52 Mb
433:external carotid artery
429:internal carotid artery
1698:blast.ncbi.nlm.nih.gov
1021:Sequence Identity (%)
979:Homology and Evolution
950:
936:N-terminal acetylation
897:
775:Chr 8: 73.2 β 73.21 Mb
449:neural layer of retina
1084:Monodelphis domestica
948:
914:of 71,343 Da, and an
895:
873:protein. There are 7
122:Chromosome 19 (human)
1722:www.ncbi.nlm.nih.gov
1650:www.ncbi.nlm.nih.gov
1523:www.ncbi.nlm.nih.gov
1397:www.ncbi.nlm.nih.gov
1373:www.ncbi.nlm.nih.gov
1348:www.proteinatlas.org
1321:www.ncbi.nlm.nih.gov
1182:two-hybrid screening
1176:Interacting Proteins
869:that code for a 657
224:Chromosome 8 (mouse)
86:C19orf44 - orthologs
1003:
413:seminiferous tubule
1122:Astyanax mexicanus
1001:
951:
898:
829:open reading frame
605:ENSMUSG00000052794
379:anterior pituitary
355:right uterine tube
1792:Science Signaling
1448:www.genecards.org
1158:
1157:
1107:Green Sea Turtle
1018:Divergence (MYA)
1008:Genus and Species
916:isoelectric point
824:
823:
820:
819:
793:
792:
758:
757:
737:
736:
707:
706:
686:
685:
656:
655:
637:
636:
611:
610:
592:
591:
566:
565:
547:
546:
495:
494:
491:
490:
469:
468:
456:
455:
394:
393:
292:
291:
191:
190:
1896:
1873:
1872:
1862:
1845:(5): 1212β1226.
1830:
1824:
1823:
1786:
1780:
1779:
1777:
1776:
1762:
1756:
1755:
1753:
1752:
1746:www.timetree.org
1738:
1732:
1731:
1729:
1728:
1714:
1708:
1707:
1705:
1704:
1690:
1684:
1683:
1681:
1680:
1666:
1660:
1659:
1657:
1656:
1642:
1633:
1632:
1612:
1606:
1605:
1595:
1563:
1557:
1556:
1554:
1553:
1539:
1533:
1532:
1530:
1529:
1515:
1506:
1505:
1503:
1502:
1488:
1482:
1481:
1479:
1478:
1464:
1458:
1457:
1455:
1454:
1440:
1431:
1430:
1428:
1427:
1413:
1407:
1406:
1404:
1403:
1389:
1383:
1382:
1380:
1379:
1364:
1358:
1357:
1355:
1354:
1340:
1331:
1330:
1328:
1327:
1313:
1298:
1297:
1295:
1294:
1284:
1278:
1277:
1266:
1260:
1259:
1248:
1242:
1232:
1221:
1211:
1169:for C19orf44 in
1004:
912:molecular weight
906:Primary Sequence
806:
805:
777:
770:
753:
741:
732:
716:
712:RefSeq (protein)
702:
690:
681:
665:
641:
622:
596:
577:
551:
532:
501:
480:
465:
445:secondary oocyte
405:
403:Top expressed in
398:
371:ventricular zone
343:
341:Top expressed in
336:
315:
298:
288:
275:
264:
249:
242:
236:
225:
213:
197:
187:
174:
163:
148:
141:
135:
124:
110:
94:
88:
47:
40:
19:
1904:
1903:
1899:
1898:
1897:
1895:
1894:
1893:
1879:
1878:
1877:
1876:
1832:
1831:
1827:
1788:
1787:
1783:
1774:
1772:
1764:
1763:
1759:
1750:
1748:
1740:
1739:
1735:
1726:
1724:
1716:
1715:
1711:
1702:
1700:
1692:
1691:
1687:
1678:
1676:
1668:
1667:
1663:
1654:
1652:
1644:
1643:
1636:
1614:
1613:
1609:
1578:(20): 3359β61.
1565:
1564:
1560:
1551:
1549:
1541:
1540:
1536:
1527:
1525:
1517:
1516:
1509:
1500:
1498:
1490:
1489:
1485:
1476:
1474:
1466:
1465:
1461:
1452:
1450:
1444:"C19orf44 Gene"
1442:
1441:
1434:
1425:
1423:
1415:
1414:
1410:
1401:
1399:
1391:
1390:
1386:
1377:
1375:
1366:
1365:
1361:
1352:
1350:
1342:
1341:
1334:
1325:
1323:
1315:
1314:
1301:
1292:
1290:
1286:
1285:
1281:
1268:
1267:
1263:
1250:
1249:
1245:
1233:
1224:
1212:
1203:
1198:
1178:
1163:
1148:XP_021343742.1
1129:XP_007246256.2
1110:XP_007072179.1
1091:XP_007489796.1
1072:XP_005661251.2
1053:XP_004277754.1
1034:XP_010359783.1
986:
981:
972:
956:
928:
910:C19orf44 has a
908:
903:
883:
875:splice variants
851:
815:View/Edit Mouse
810:View/Edit Human
773:
766:
763:Location (UCSC)
749:
728:
724:
698:
677:
673:
586:ENSG00000105072
461:
452:
447:
443:
439:
435:
431:
427:
423:
419:
415:
401:
390:
385:
381:
377:
373:
369:
365:
361:
357:
353:
339:
283:
270:
262:
252:
251:
250:
243:
223:
200:Gene location (
182:
169:
161:
151:
150:
149:
142:
120:
97:Gene location (
56:
43:
36:
17:
12:
11:
5:
1902:
1900:
1892:
1891:
1881:
1880:
1875:
1874:
1825:
1781:
1757:
1733:
1709:
1685:
1661:
1634:
1607:
1572:Bioinformatics
1558:
1547:www.expasy.org
1534:
1507:
1483:
1472:web.expasy.org
1459:
1432:
1408:
1384:
1359:
1332:
1299:
1279:
1261:
1243:
1222:
1200:
1199:
1197:
1194:
1177:
1174:
1162:
1159:
1156:
1155:
1152:
1149:
1146:
1143:
1137:
1136:
1133:
1130:
1127:
1126:Mexican Tetra
1124:
1118:
1117:
1114:
1111:
1108:
1105:
1103:Chelonia mydas
1099:
1098:
1095:
1092:
1089:
1086:
1080:
1079:
1076:
1073:
1070:
1067:
1061:
1060:
1057:
1054:
1051:
1050:Killer Whale
1048:
1042:
1041:
1038:
1035:
1032:
1029:
1023:
1022:
1019:
1016:
1013:
1010:
985:
982:
980:
977:
971:
968:
955:
952:
927:
924:
907:
904:
902:
899:
882:
879:
861:that is 3,446
850:
847:
827:Chromosome 19
822:
821:
818:
817:
812:
802:
801:
795:
794:
791:
790:
788:
786:
779:
778:
771:
764:
760:
759:
756:
755:
745:
744:
738:
735:
734:
720:
719:
713:
709:
708:
705:
704:
694:
693:
687:
684:
683:
669:
668:
662:
658:
657:
654:
653:
645:
644:
638:
635:
634:
626:
625:
619:
613:
612:
609:
608:
600:
599:
593:
590:
589:
581:
580:
574:
568:
567:
564:
563:
555:
554:
548:
545:
544:
536:
535:
529:
523:
522:
517:
512:
508:
507:
497:
496:
493:
492:
489:
488:
485:
484:
477:
471:
470:
467:
466:
458:
457:
454:
453:
451:
450:
446:
442:
438:
434:
430:
426:
425:primary oocyte
422:
418:
414:
410:
407:
406:
395:
392:
391:
389:
388:
384:
380:
376:
372:
368:
364:
360:
356:
352:
348:
345:
344:
332:
331:
323:
312:
306:
305:
302:RNA expression
294:
293:
290:
289:
281:
277:
276:
268:
265:
260:
254:
253:
244:
237:
231:
227:
226:
221:
215:
214:
206:
205:
193:
192:
189:
188:
180:
176:
175:
167:
164:
159:
153:
152:
143:
136:
130:
126:
125:
118:
112:
111:
103:
102:
90:
89:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1901:
1890:
1887:
1886:
1884:
1870:
1866:
1861:
1856:
1852:
1848:
1844:
1840:
1836:
1829:
1826:
1821:
1817:
1813:
1809:
1805:
1801:
1797:
1793:
1785:
1782:
1771:
1770:www.genome.jp
1767:
1761:
1758:
1747:
1743:
1737:
1734:
1723:
1719:
1713:
1710:
1699:
1695:
1689:
1686:
1675:
1674:www.genome.jp
1671:
1665:
1662:
1651:
1647:
1641:
1639:
1635:
1630:
1626:
1622:
1618:
1611:
1608:
1603:
1599:
1594:
1589:
1585:
1581:
1577:
1573:
1569:
1562:
1559:
1548:
1544:
1538:
1535:
1524:
1520:
1514:
1512:
1508:
1497:
1496:www.ebi.ac.uk
1493:
1487:
1484:
1473:
1469:
1463:
1460:
1449:
1445:
1439:
1437:
1433:
1422:
1418:
1412:
1409:
1398:
1394:
1388:
1385:
1374:
1370:
1363:
1360:
1349:
1345:
1339:
1337:
1333:
1322:
1318:
1312:
1310:
1308:
1306:
1304:
1300:
1289:
1283:
1280:
1275:
1271:
1265:
1262:
1257:
1253:
1247:
1244:
1240:
1236:
1231:
1229:
1227:
1223:
1219:
1215:
1210:
1208:
1206:
1202:
1195:
1193:
1191:
1187:
1183:
1175:
1173:
1172:
1171:Homo sapiens.
1168:
1165:There are no
1160:
1153:
1150:
1147:
1144:
1142:
1139:
1138:
1134:
1131:
1128:
1125:
1123:
1120:
1119:
1115:
1112:
1109:
1106:
1104:
1101:
1100:
1096:
1093:
1090:
1087:
1085:
1082:
1081:
1077:
1074:
1071:
1068:
1066:
1063:
1062:
1058:
1055:
1052:
1049:
1047:
1044:
1043:
1039:
1036:
1033:
1030:
1028:
1025:
1024:
1020:
1017:
1014:
1011:
1009:
1006:
1005:
999:
998:
994:
990:
983:
978:
976:
969:
967:
965:
961:
953:
947:
943:
941:
937:
933:
925:
923:
921:
917:
913:
905:
900:
894:
890:
889:on 19p13.11.
888:
880:
878:
876:
872:
868:
864:
860:
856:
848:
846:
844:
840:
836:
832:
830:
816:
811:
807:
803:
800:
796:
789:
787:
784:
780:
776:
772:
769:
765:
761:
754:
752:
746:
742:
739:
733:
731:
727:
721:
717:
714:
710:
703:
701:
695:
691:
688:
682:
680:
676:
670:
666:
663:
661:RefSeq (mRNA)
659:
652:
651:
646:
642:
639:
633:
632:
627:
623:
620:
618:
614:
607:
606:
601:
597:
594:
588:
587:
582:
578:
575:
573:
569:
562:
561:
556:
552:
549:
543:
542:
537:
533:
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1798:(189): rs8.
1795:
1791:
1784:
1773:. Retrieved
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1046:Orcinus orca
1045:
1026:
1012:Common Name
1007:
987:
973:
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954:Localization
929:
909:
884:
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826:
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748:
726:NP_001275763
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697:
675:NM_001288834
672:
648:
629:
603:
584:
558:
539:
519:
514:
417:spermatocyte
359:right testis
325:
318:
53:External IDs
997:NCBI Blast.
940:sumoylation
863:nucleotides
383:right ovary
363:left testis
284:73,214,845
271:73,197,724
183:16,521,352
170:16,496,394
31:Identifiers
1775:2018-02-25
1751:2018-02-25
1727:2018-05-06
1703:2018-05-06
1679:2018-05-06
1655:2018-05-06
1623:: 147β52.
1552:2018-05-06
1528:2018-02-17
1501:2018-05-06
1477:2018-05-06
1453:2018-02-17
1426:2018-04-17
1402:2018-02-05
1378:2018-02-05
1353:2018-05-06
1326:2018-02-05
1293:2018-05-06
1241:, May 2017
1220:, May 2017
1196:References
1069:Wild Boar
1065:Sus scrofa
970:Expression
887:chromosome
871:amino acid
855:base pairs
387:left ovary
329:(ortholog)
66:HomoloGene
1190:spermatid
989:Orthologs
984:Orthologs
751:NP_082446
730:NP_115583
700:NM_028170
679:NM_032207
505:Orthologs
421:spermatid
74:GeneCards
1883:Category
1869:25416956
1812:21900206
1602:26069263
1237:–
1216:–
1167:paralogs
1161:Paralogs
1145:Scallop
1088:Opossum
920:EMBL-EBI
799:Wikidata
441:gastrula
367:testicle
162:19p13.11
78:C19orf44
45:C19orf44
22:C19orf44
1860:4266588
1820:7418133
1629:9322029
1593:4595897
1239:Ensembl
1218:Ensembl
1188:), and
964:cytosol
960:nucleus
901:Protein
835:protein
617:UniProt
572:Ensembl
511:Species
304:pattern
62:1919504
38:Aliases
1867:
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1600:
1590:
932:ExPASy
785:search
783:PubMed
650:Q922C1
631:Q9H6X5
527:Entrez
475:BioGPS
1816:S2CID
1186:CDC37
1154:24.4
1135:28.2
1116:35.2
1097:45.5
1078:60.1
1059:83.2
1040:86.9
881:Locus
867:exons
833:is a
560:72254
541:84167
520:Mouse
515:Human
375:gonad
351:sperm
327:Mouse
320:Human
267:Start
202:Mouse
166:Start
99:Human
70:12975
1865:PMID
1839:Cell
1808:PMID
1625:PMID
1598:PMID
1421:NCBI
1151:797
1132:435
1113:312
1094:159
859:mRNA
849:Gene
839:gene
310:Bgee
258:Band
219:Chr.
157:Band
116:Chr.
1855:PMC
1847:doi
1843:159
1800:doi
1588:PMC
1580:doi
1075:96
1056:96
1037:29
962:or
843:DUF
483:n/a
280:End
179:End
82:OMA
58:MGI
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