50:
369:
3003:
3033:
3043:
3023:
3013:
376:
There is no cure for CTCL, but there are a variety of treatment options available and some CTCL patients are able to live normal lives with this cancer, although symptoms can be debilitating and painful, even in earlier stages. FDA approved treatments include the following:
1155:
1136:
354:
2169:
841:
Khamaysi, Z.; Ben-Arieh, Y.; Izhak, OB.; Epelbaum, R.; Dann, EJ.; Bergman, R. (Feb 2008). "The applicability of the new WHO-EORTC classification of primary cutaneous lymphomas to a single referral center".
1913:
319:
1064:
1467:
563:(HTLV) with the adult T-cell leukemia/lymphoma subtype. No definitive link between any viral infection or environmental factor has been definitely shown with other CTCL subtypes.
1584:
1174:
670:
Pimpinelli, Nicola; Olsen, Elise A.; Santucci, Marco; Vonderheid, Eric; Haeffner, Andreas C.; Stevens, Seth; Burg, Guenter; Cerroni, Lorenzo; Dreno, Brigitte (December 2005).
2174:
176:
The cause of CTCL remains largely unknown, but several external risk factors have been proposed as potential triggers and promoters of the disease. These include the use of
1983:
2197:
1549:
3067:
1939:
314:
252:
A point-based algorithm for the diagnosis for early forms of cutaneous T-cell lymphoma was proposed by the
International Society for Cutaneous Lymphomas in 2005.
1278:
885:
Melchers RC, Willemze R, van de Loo M, van Doorn R, Jansen PM, Cleven AH, Solleveld N, Bekkenk MW, van Kester MS, Diercks GF, Vermeer MH, Quint KD (June 2020).
304:
1629:
2142:
2532:
2181:
1727:
1472:
1606:
420:
Histone deacetylase (HDAC) inhibitors are shown to have antiproliferative and cytotoxic properties against CTCL. Other (off label) treatments include:
2873:
942:
Saleh JS, Subtil A, Hristov AC (August 2023). "Primary cutaneous T-cell lymphoma: a review of the most common entities with focus on recent updates".
1707:
1505:
1061:
2472:
2131:
1805:
1359:
747:
Sidiropoulos, KG; Martinez-Escala, ME; Yelamos, O; Guitart, J; Sidiropoulos, M (December 2015). "Primary cutaneous T-cell lymphomas: a review".
1978:
1797:
1348:
1098:
887:"Clinical, Histologic, and Molecular Characteristics of Anaplastic Lymphoma Kinase-positive Primary Cutaneous Anaplastic Large Cell Lymphoma"
731:
2772:
2126:
611:
Ghazawi, Feras M.; Alghazawi, Nebras; Le, Michelle; Netchiporouk, Elena; Glassman, Steven J.; Sasseville, Denis; Litvinov, Ivan V. (2019).
2082:
1702:
1500:
1384:
1105:
Frequency of lymphoid neoplasms. (Source: Modified from WHO Blue Book on Tumour of
Hematopoietic and Lymphoid Tissues. 2001, p. 2001.)
2908:
2250:
1973:
1243:
1271:
1046:
3026:
1934:
309:
790:
Willemze, R.; Jaffe, ES.; Burg, G.; Cerroni, L.; Berti, E.; Swerdlow, SH.; Ralfkiaer, E.; Chimenti, S.; et al. (May 2005).
299:
2898:
2332:
2164:
2156:
2015:
1893:
1832:
1818:
1712:
1653:
1490:
1416:
349:
671:
1062:
Elorac, Inc. Announces Orphan Drug
Designation for Novel Topical Treatment for Pruritus in Cutaneous T-cell Lymphoma (CTCL)
2212:
2122:
2072:
1968:
1697:
1481:
549:
2878:
2104:
2010:
1993:
1801:
1355:
1264:
577:
334:
185:
181:
2522:
2045:
1918:
1624:
324:
613:"Environmental and Other Extrinsic Risk Factors Contributing to the Pathogenesis of Cutaneous T Cell Lymphoma (CTCL)"
2502:
1960:
560:
31:
2931:
1848:
1689:
1611:
572:
49:
2723:
2645:
2640:
2560:
2320:
2050:
1878:
1247:
1189:
886:
344:
289:
236:
219:
1516:
124:
to appear. These lesions change shape as the disease progresses, typically beginning as what appears to be a
2703:
2677:
207:
2067:
1618:
540:
lotion as a treatment for pruritus in cutaneous T-cell lymphoma to a pharmaceutical company called Elorac.
193:
2295:
2243:
1944:
1923:
1837:
986:
Devata, S; Wilcox, RA (June 2016). "Cutaneous T-Cell
Lymphoma: A Review with a Focus on Targeted Agents".
294:
3077:
2946:
2832:
2805:
2778:
2730:
2684:
2379:
2076:
1666:
1560:
523:
339:
224:
1639:
1462:
2966:
2926:
2793:
2607:
2602:
2582:
2517:
2369:
1873:
1485:
1396:
279:
230:
93:
3046:
2988:
2971:
2630:
2347:
1673:
1457:
1427:
1159:
382:
177:
156:, the most common, though not the only types. Among the symptoms for the aforementioned types are:
3032:
2936:
2893:
2883:
2672:
2625:
2592:
2587:
2337:
2315:
2137:
1090:
1011:
924:
867:
772:
180:
diuretics, therapy-induced immunosuppression, and possible infections by a range of viral (e.g.,
161:
284:
153:
3072:
3006:
2888:
2858:
2837:
2800:
2783:
2698:
2662:
2652:
2547:
2467:
2411:
2374:
2359:
2300:
2267:
2236:
2217:
1887:
1868:
1857:
1647:
1537:
1452:
1200:
1094:
1042:
1003:
959:
916:
859:
823:
764:
727:
704:
652:
634:
465:
261:
149:
68:
2708:
2693:
2570:
2445:
2401:
1987:
1766:
1634:
1533:
1256:
1034:
995:
951:
906:
898:
851:
813:
803:
756:
694:
686:
642:
624:
553:
514:
459:
329:
368:
3036:
2981:
2842:
2827:
2810:
2750:
2745:
2689:
2667:
2364:
2310:
2290:
1760:
1755:
1564:
1448:
1314:
1309:
1068:
447:
198:
157:
597:
17:
2868:
2822:
2635:
2565:
2384:
2207:
1183:
1179:
1083:
647:
612:
426:
215:
1168:
1164:
3061:
2951:
2740:
2735:
2597:
2537:
2440:
2114:
1813:
1722:
1678:
1495:
1369:
928:
470:
101:
1015:
871:
776:
3016:
2956:
2941:
2767:
2492:
2342:
2327:
2273:
1717:
1379:
1229:
536:
In 2010, the U.S. Food and Drug
Administration granted orphan drug designation for
486:
453:
241:
955:
760:
61:
1194:
902:
855:
2815:
2760:
2657:
2512:
2487:
2305:
1391:
1038:
552:, 2% of cases are cutaneous T cell lymphomas. CTCL is more common in men and in
508:
502:
495:
491:
480:
441:
2903:
808:
791:
690:
2788:
2755:
2527:
2477:
2462:
2457:
2450:
2435:
2425:
1287:
1205:
1149:
1145:
999:
528:
475:
437:
431:
406:
399:
389:
165:
137:
117:
73:
57:
638:
598:"Cutaneous T-Cell Lymphoma: Practice Essentials, Background, Pathophysiology"
2976:
2718:
2713:
2577:
2555:
2430:
2394:
1224:
629:
413:
264:
is the most common form of CTCL and is responsible for half of all cases. A
113:
1007:
963:
920:
863:
827:
768:
708:
656:
2482:
2259:
2202:
2030:
1741:
1304:
1291:
537:
393:
77:
1128:
911:
556:
people. The incidence of CTCL in men is 1.6 times higher than in women.
355:
Primary cutaneous acral CD8 positive T cell lymphoproliferative disorder
2961:
2421:
2389:
2282:
818:
699:
1750:
1140:
121:
109:
105:
97:
260:
Cutaneous T-cell lymphoma may be divided into the several subtypes.
1573:
1438:
1422:
367:
269:
211:
203:
133:
2036:
1930:
1909:
1827:
1569:
1544:
1524:
1520:
1407:
1325:
1320:
129:
125:
2232:
1260:
409:(Istodax) a cyclic peptide histone deacetylase (HDAC) inhibitor
1776:
1771:
1661:
265:
189:
1089:. Hagerstown, MD: Lippincott Williams & Wilkins. p.
244:). The level of evidence varies among the different factors.
402:(Zolinza) a hydroxymate histone deacetylase (HDAC) inhibitor
2228:
1914:
Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
722:
James, William D.; Berger, Timothy G.; et al. (2006).
320:
Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
104:. Unlike most non-Hodgkin lymphomas (which are generally
30:"CTCL" redirects here. For the book by Loren Pope, see
1033:. Springer International Publishing. pp. 23–34.
1118:
2919:
2857:
2618:
2546:
2501:
2410:
2281:
2266:
2190:
2155:
2113:
2095:
2059:
2029:
2002:
1957:
1902:
1856:
1847:
1787:
1749:
1740:
1688:
1598:
1559:
1515:
1437:
1406:
1368:
1347:
1336:
1303:
1215:
1122:
724:
67:
42:
1984:Peripheral T-cell lymphoma not otherwise specified
1082:
792:"WHO-EORTC classification for cutaneous lymphomas"
1806:Precursor T acute lymphoblastic leukemia/lymphoma
1360:Precursor B acute lymphoblastic leukemia/lymphoma
1029:Beigi, Pooya Khan Mohammad (2017). "Treatment".
350:Primary cutaneous anaplastic large-cell lymphoma
1550:Nodular lymphocyte predominant Hodgkin lymphoma
222:) and bacterial or fungal pathogens (including
679:Journal of the American Academy of Dermatology
559:There is some evidence of a relationship with
2244:
1940:Secondary cutaneous CD30+ large-cell lymphoma
1272:
1248:dermal-infiltrative/cutaneous-t-cell-lymphoma
981:
979:
977:
975:
973:
315:Secondary cutaneous CD30+ large cell lymphoma
305:Pityriasis lichenoides et varioliformis acuta
116:T cells in the body initially migrate to the
8:
1630:Post-transplant lymphoproliferative disorder
1585:immunoproliferative immunoglobulin disorders
2143:Diffuse infiltrative lymphocytosis syndrome
108:-related), CTCL is caused by a mutation of
2533:Reproductive endocrinology and infertility
2278:
2251:
2237:
2229:
2182:Jessner lymphocytic infiltrate of the skin
1853:
1784:
1746:
1728:Primary cutaneous follicle center lymphoma
1473:Primary cutaneous follicle center lymphoma
1344:
1333:
1300:
1279:
1265:
1257:
1119:
1085:Clinical hematology: theory and procedures
891:The American Journal of Surgical Pathology
531:(inhibits purine nucleoside phosphorylase)
39:
2874:Bachelor of Medicine, Bachelor of Surgery
910:
817:
807:
698:
646:
628:
1708:Primary cutaneous marginal zone lymphoma
1506:Primary cutaneous marginal zone lymphoma
988:American Journal of Clinical Dermatology
2170:with bandlike and perivascular patterns
2132:Autoimmune lymphoproliferative syndrome
589:
1979:Enteropathy-associated T-cell lymphoma
1031:Clinician's Guide to Mycosis Fungoides
3068:Lymphoid-related cutaneous conditions
7:
3012:
2773:Physical medicine and rehabilitation
2127:X-linked lymphoproliferative disease
3022:
2083:Large granular lymphocytic leukemia
1703:Intravascular large B-cell lymphoma
456:(broad and narrow band UVB or PUVA)
272:classification has been developed.
132:and eventually forming plaques and
60:showing cutaneous T-cell lymphoma.
2909:Medical Scientist Training Program
672:"Defining early mycosis fungoides"
148:The presentation depends if it is
25:
3041:
3031:
3021:
3011:
3002:
3001:
48:
3042:
1935:CD30+ cutaneous T-cell lymphoma
310:CD30+ cutaneous T-cell lymphoma
300:Pityriasis lichenoides chronica
2899:Doctor of Osteopathic Medicine
2333:Oral and maxillofacial surgery
2165:Cutaneous lymphoid hyperplasia
2157:Cutaneous lymphoid hyperplasia
2016:Adult T-cell leukemia/lymphoma
1894:Adult T-cell leukemia/lymphoma
1833:Anaplastic large-cell lymphoma
1713:Primary cutaneous immunocytoma
1654:Splenic marginal zone lymphoma
1:
2213:Lymphoproliferative disorders
2123:Lymphoproliferative disorders
2073:Extranodal NK-T-cell lymphoma
1945:Lymphomatoid papulosis type A
1924:Lymphomatoid papulosis type B
1838:Lymphomatoid papulosis type A
1698:Diffuse large B-cell lymphoma
1081:Turgeon, Mary Louise (2005).
956:10.1016/j.humpath.2023.06.001
761:10.1136/jclinpath-2015-203133
749:Journal of Clinical Pathology
550:cancers involving lymphocytes
2879:Bachelor of Medical Sciences
2646:Neurosurgical anesthesiology
2105:Acute biphenotypic leukaemia
1994:Subcutaneous T-cell lymphoma
903:10.1097/PAS.0000000000001449
856:10.1097/DAD.0b013e31815f9841
578:List of cutaneous conditions
494:and other purine analogues (
434:(Targretin) gel and capsules
335:Subcutaneous T-cell lymphoma
140:to other parts of the body.
27:Type of immune system cancer
2046:Aggressive NK-cell leukemia
1919:Pleomorphic T-cell lymphoma
1625:Lymphomatoid granulomatosis
1039:10.1007/978-3-319-47907-1_6
325:Pleomorphic T-cell lymphoma
3094:
809:10.1182/blood-2004-09-3502
691:10.1016/j.jaad.2005.08.057
561:human T-lymphotropic virus
32:Colleges That Change Lives
29:
2997:
1299:
1000:10.1007/s40257-016-0177-5
573:Cutaneous B-cell lymphoma
498:, 2-deoxychloroadenosine)
162:enlarged liver and spleen
86:Cutaneous T-cell lymphoma
56:
47:
43:Cutaneous T-cell lymphoma
18:Cutaneous T cell lymphoma
2833:Transplantation medicine
2724:Clinical neurophysiology
2641:Obstetric anesthesiology
2561:Interventional radiology
2321:Digestive system surgery
2198:Hematological malignancy
2051:Blastic NK cell lymphoma
1879:Granulomatous slack skin
1635:Classic Hodgkin lymphoma
1534:Classic Hodgkin lymphoma
519:Bone marrow / stem cells
345:Blastic NK-cell lymphoma
290:Granulomatous slack skin
237:Chlamydophila pneumoniae
220:Merkel cell polyomavirus
2704:Intensive care medicine
2678:Mass gathering medicine
2523:Maternal–fetal medicine
630:10.3389/fonc.2019.00300
2296:Cardiothoracic surgery
373:
295:Lymphomatoid papulosis
2947:Personalized medicine
2806:Reproductive medicine
2731:Occupational medicine
2685:Evolutionary medicine
2077:Angiocentric lymphoma
1667:AIDS-related lymphoma
1491:Splenic marginal zone
726:. Saunders Elsevier.
617:Frontiers in Oncology
371:
340:Angiocentric lymphoma
225:Staphylococcus aureus
96:, which is a type of
2967:Traditional medicine
2927:Alternative medicine
2794:Addiction psychiatry
2608:Transfusion medicine
2603:Medical microbiology
2518:Gynecologic oncology
2370:Reproductive surgery
2175:with nodular pattern
1874:Pagetoid reticulosis
1486:marginal zone B-cell
416:(mogamulizumab-kpkc)
280:Pagetoid reticulosis
231:Mycobacterium leprae
158:enlarged lymph nodes
94:non-Hodgkin lymphoma
2989:History of medicine
2972:Veterinary medicine
2779:Preventive medicine
2631:Adolescent medicine
2473:Infectious diseases
1674:Helicobacter pylori
1501:Nodal marginal zone
1428:Hairy cell leukemia
1294:and related disease
383:Denileukin diftitox
178:hydrochlorothiazide
164:, and non-specific
2937:Molecular oncology
2894:Doctor of Medicine
2884:Master of Medicine
2801:Radiation oncology
2673:Emergency medicine
2626:Addiction medicine
2593:Clinical chemistry
2588:Clinical pathology
2380:Transplant surgery
2338:Orthopedic surgery
2316:Colorectal surgery
2218:Lymphoid leukemias
2138:Leukemoid reaction
1974:Angioimmunoblastic
1640:Burkitt's lymphoma
1216:External resources
1067:2010-12-30 at the
844:Am J Dermatopathol
450:(nitrogen mustard)
374:
194:Epstein-Barr virus
144:Signs and symptoms
128:which can be very
120:, causing various
3055:
3054:
2889:Master of Surgery
2853:
2852:
2838:Tropical medicine
2784:Prison healthcare
2699:Hospital medicine
2663:Disaster medicine
2653:Aviation medicine
2468:Hospital medicine
2375:Surgical oncology
2360:Pediatric surgery
2354:
2301:Endocrine surgery
2226:
2225:
2151:
2150:
2091:
2090:
2025:
2024:
1953:
1952:
1869:Mycosis fungoides
1736:
1735:
1594:
1593:
1538:Nodular sclerosis
1453:follicular B cell
1239:
1238:
1100:978-0-7817-5007-3
733:978-0-7216-2921-6
466:radiation therapy
425:Topical and oral
262:Mycosis fungoides
150:mycosis fungoides
83:
82:
37:Medical condition
16:(Redirected from
3085:
3045:
3044:
3035:
3025:
3024:
3015:
3014:
3005:
3004:
2709:Medical genetics
2694:General practice
2571:Nuclear medicine
2446:Gastroenterology
2402:Vascular surgery
2352:
2279:
2253:
2246:
2239:
2230:
1988:Lennert lymphoma
1854:
1785:
1747:
1612:Primary effusion
1345:
1334:
1301:
1281:
1274:
1267:
1258:
1120:
1108:
1107:
1088:
1078:
1072:
1059:
1053:
1052:
1026:
1020:
1019:
983:
968:
967:
939:
933:
932:
914:
882:
876:
875:
838:
832:
831:
821:
811:
787:
781:
780:
744:
738:
737:
719:
713:
712:
702:
685:(6): 1053–1063.
676:
667:
661:
660:
650:
632:
608:
602:
601:
594:
554:African-American
515:Cyclophosphamide
460:Electron therapy
330:Lennert lymphoma
92:) is a class of
52:
40:
21:
3093:
3092:
3088:
3087:
3086:
3084:
3083:
3082:
3058:
3057:
3056:
3051:
2993:
2982:Chief physician
2915:
2860:
2849:
2843:Travel medicine
2828:Sports medicine
2811:Sexual medicine
2751:Palliative care
2746:Pain management
2690:Family medicine
2668:Diving medicine
2614:
2542:
2504:
2497:
2413:
2406:
2365:Plastic surgery
2311:General surgery
2291:Cardiac surgery
2272:
2270:
2262:
2257:
2227:
2222:
2186:
2147:
2109:
2097:
2087:
2055:
2034:
2021:
1998:
1959:
1949:
1898:
1843:
1791:
1789:
1764:
1759:
1753:
1732:
1684:
1590:
1567:
1555:
1511:
1449:germinal center
1433:
1402:
1364:
1340:
1338:
1318:
1313:
1307:
1295:
1285:
1254:
1240:
1235:
1234:
1211:
1210:
1131:
1117:
1112:
1111:
1101:
1080:
1079:
1075:
1069:Wayback Machine
1060:
1056:
1049:
1028:
1027:
1023:
985:
984:
971:
944:Human Pathology
941:
940:
936:
884:
883:
879:
840:
839:
835:
802:(10): 3768–85.
789:
788:
784:
755:(12): 1003–10.
746:
745:
741:
734:
721:
720:
716:
674:
669:
668:
664:
610:
609:
605:
596:
595:
591:
586:
569:
546:
534:
524:transplantation
448:Mechlorethamine
427:corticosteroids
366:
361:
285:Sézary syndrome
258:
250:
199:Cytomegalovirus
174:
154:Sézary syndrome
146:
38:
35:
28:
23:
22:
15:
12:
11:
5:
3091:
3089:
3081:
3080:
3075:
3070:
3060:
3059:
3053:
3052:
3050:
3049:
3039:
3029:
3019:
3009:
2998:
2995:
2994:
2992:
2991:
2986:
2985:
2984:
2974:
2969:
2964:
2959:
2954:
2949:
2944:
2939:
2934:
2929:
2923:
2921:
2920:Related topics
2917:
2916:
2914:
2913:
2912:
2911:
2901:
2896:
2891:
2886:
2881:
2876:
2871:
2869:Medical school
2865:
2863:
2855:
2854:
2851:
2850:
2848:
2847:
2846:
2845:
2835:
2830:
2825:
2823:Sleep medicine
2820:
2819:
2818:
2808:
2803:
2798:
2797:
2796:
2786:
2781:
2776:
2770:
2765:
2764:
2763:
2753:
2748:
2743:
2738:
2733:
2728:
2727:
2726:
2716:
2711:
2706:
2701:
2696:
2687:
2682:
2681:
2680:
2670:
2665:
2660:
2655:
2650:
2649:
2648:
2643:
2636:Anesthesiology
2633:
2628:
2622:
2620:
2616:
2615:
2613:
2612:
2611:
2610:
2605:
2600:
2595:
2590:
2585:
2575:
2574:
2573:
2568:
2566:Neuroradiology
2563:
2552:
2550:
2544:
2543:
2541:
2540:
2535:
2530:
2525:
2520:
2515:
2509:
2507:
2503:Obstetrics and
2499:
2498:
2496:
2495:
2490:
2485:
2480:
2475:
2470:
2465:
2460:
2455:
2454:
2453:
2443:
2438:
2433:
2428:
2418:
2416:
2408:
2407:
2405:
2404:
2399:
2398:
2397:
2387:
2385:Trauma surgery
2382:
2377:
2372:
2367:
2362:
2357:
2356:
2355:
2348:Otolaryngology
2345:
2340:
2335:
2330:
2325:
2324:
2323:
2318:
2308:
2303:
2298:
2293:
2287:
2285:
2276:
2274:subspecialties
2264:
2263:
2258:
2256:
2255:
2248:
2241:
2233:
2224:
2223:
2221:
2220:
2215:
2210:
2208:Leukemia cutis
2205:
2200:
2194:
2192:
2188:
2187:
2185:
2184:
2179:
2178:
2177:
2172:
2161:
2159:
2153:
2152:
2149:
2148:
2146:
2145:
2140:
2135:
2129:
2119:
2117:
2111:
2110:
2108:
2107:
2101:
2099:
2093:
2092:
2089:
2088:
2086:
2085:
2080:
2063:
2061:
2057:
2056:
2054:
2053:
2048:
2042:
2040:
2027:
2026:
2023:
2022:
2020:
2019:
2006:
2004:
2000:
1999:
1997:
1996:
1991:
1981:
1976:
1971:
1965:
1963:
1955:
1954:
1951:
1950:
1948:
1947:
1942:
1937:
1927:
1926:
1921:
1916:
1906:
1904:
1900:
1899:
1897:
1896:
1888:Sézary disease
1882:
1881:
1876:
1871:
1862:
1860:
1851:
1845:
1844:
1842:
1841:
1835:
1823:
1822:
1819:Prolymphocytic
1809:
1795:
1793:
1782:
1781:
1780:
1774:
1744:
1738:
1737:
1734:
1733:
1731:
1730:
1725:
1720:
1715:
1710:
1705:
1700:
1694:
1692:
1686:
1685:
1683:
1682:
1670:
1658:
1657:
1656:
1644:
1643:
1642:
1637:
1632:
1627:
1615:
1602:
1600:
1596:
1595:
1592:
1591:
1589:
1588:
1579:
1577:
1557:
1556:
1554:
1553:
1541:
1530:
1528:
1513:
1512:
1510:
1509:
1503:
1498:
1493:
1477:
1476:
1470:
1465:
1460:
1444:
1442:
1435:
1434:
1432:
1431:
1419:
1417:Prolymphocytic
1413:
1411:
1404:
1403:
1401:
1400:
1388:
1375:
1373:
1366:
1365:
1363:
1353:
1351:
1342:
1331:
1330:
1329:
1297:
1296:
1286:
1284:
1283:
1276:
1269:
1261:
1252:
1251:
1237:
1236:
1233:
1232:
1220:
1219:
1217:
1213:
1212:
1209:
1208:
1197:
1186:
1171:
1152:
1132:
1127:
1126:
1124:
1123:Classification
1116:
1115:External links
1113:
1110:
1109:
1099:
1073:
1054:
1047:
1021:
969:
934:
897:(6): 776–781.
877:
833:
782:
739:
732:
714:
662:
603:
588:
587:
585:
582:
581:
580:
575:
568:
565:
545:
542:
533:
532:
526:
520:
517:
512:
506:
499:
489:
484:
478:
473:
468:
462:
457:
451:
445:
435:
429:
422:
418:
417:
410:
403:
396:
392:(Targretin) a
386:
365:
362:
360:
359:
358:
357:
352:
347:
342:
337:
332:
327:
322:
317:
312:
307:
302:
297:
292:
287:
282:
274:
257:
256:Classification
254:
249:
246:
216:Polyomaviruses
173:
170:
145:
142:
81:
80:
71:
65:
64:
54:
53:
45:
44:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
3090:
3079:
3076:
3074:
3071:
3069:
3066:
3065:
3063:
3048:
3040:
3038:
3034:
3030:
3028:
3020:
3018:
3010:
3008:
3000:
2999:
2996:
2990:
2987:
2983:
2980:
2979:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2955:
2953:
2952:Public health
2950:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2932:Allied health
2930:
2928:
2925:
2924:
2922:
2918:
2910:
2907:
2906:
2905:
2902:
2900:
2897:
2895:
2892:
2890:
2887:
2885:
2882:
2880:
2877:
2875:
2872:
2870:
2867:
2866:
2864:
2862:
2856:
2844:
2841:
2840:
2839:
2836:
2834:
2831:
2829:
2826:
2824:
2821:
2817:
2814:
2813:
2812:
2809:
2807:
2804:
2802:
2799:
2795:
2792:
2791:
2790:
2787:
2785:
2782:
2780:
2777:
2774:
2771:
2769:
2766:
2762:
2759:
2758:
2757:
2754:
2752:
2749:
2747:
2744:
2742:
2741:Oral medicine
2739:
2737:
2736:Ophthalmology
2734:
2732:
2729:
2725:
2722:
2721:
2720:
2717:
2715:
2712:
2710:
2707:
2705:
2702:
2700:
2697:
2695:
2691:
2688:
2686:
2683:
2679:
2676:
2675:
2674:
2671:
2669:
2666:
2664:
2661:
2659:
2656:
2654:
2651:
2647:
2644:
2642:
2639:
2638:
2637:
2634:
2632:
2629:
2627:
2624:
2623:
2621:
2617:
2609:
2606:
2604:
2601:
2599:
2598:Cytopathology
2596:
2594:
2591:
2589:
2586:
2584:
2581:
2580:
2579:
2576:
2572:
2569:
2567:
2564:
2562:
2559:
2558:
2557:
2554:
2553:
2551:
2549:
2545:
2539:
2538:Urogynecology
2536:
2534:
2531:
2529:
2526:
2524:
2521:
2519:
2516:
2514:
2511:
2510:
2508:
2506:
2500:
2494:
2491:
2489:
2486:
2484:
2481:
2479:
2476:
2474:
2471:
2469:
2466:
2464:
2461:
2459:
2456:
2452:
2449:
2448:
2447:
2444:
2442:
2441:Endocrinology
2439:
2437:
2434:
2432:
2429:
2427:
2423:
2420:
2419:
2417:
2415:
2409:
2403:
2400:
2396:
2393:
2392:
2391:
2388:
2386:
2383:
2381:
2378:
2376:
2373:
2371:
2368:
2366:
2363:
2361:
2358:
2351:
2350:
2349:
2346:
2344:
2341:
2339:
2336:
2334:
2331:
2329:
2326:
2322:
2319:
2317:
2314:
2313:
2312:
2309:
2307:
2304:
2302:
2299:
2297:
2294:
2292:
2289:
2288:
2286:
2284:
2280:
2277:
2275:
2269:
2265:
2261:
2254:
2249:
2247:
2242:
2240:
2235:
2234:
2231:
2219:
2216:
2214:
2211:
2209:
2206:
2204:
2201:
2199:
2196:
2195:
2193:
2189:
2183:
2180:
2176:
2173:
2171:
2168:
2167:
2166:
2163:
2162:
2160:
2158:
2154:
2144:
2141:
2139:
2136:
2133:
2130:
2128:
2124:
2121:
2120:
2118:
2116:
2115:Lymphocytosis
2112:
2106:
2103:
2102:
2100:
2094:
2084:
2081:
2078:
2074:
2070:
2069:
2065:
2064:
2062:
2058:
2052:
2049:
2047:
2044:
2043:
2041:
2038:
2032:
2028:
2017:
2013:
2012:
2008:
2007:
2005:
2001:
1995:
1992:
1989:
1985:
1982:
1980:
1977:
1975:
1972:
1970:
1969:Hepatosplenic
1967:
1966:
1964:
1962:
1956:
1946:
1943:
1941:
1938:
1936:
1932:
1929:
1928:
1925:
1922:
1920:
1917:
1915:
1911:
1908:
1907:
1905:
1901:
1895:
1892:
1891:
1890:
1889:
1886:
1880:
1877:
1875:
1872:
1870:
1867:
1864:
1863:
1861:
1859:
1855:
1852:
1850:
1846:
1839:
1836:
1834:
1830:
1829:
1825:
1824:
1820:
1816:
1815:
1814:prolymphocyte
1811:
1810:
1807:
1803:
1799:
1796:
1794:
1786:
1783:
1778:
1775:
1773:
1770:
1769:
1768:
1762:
1757:
1752:
1748:
1745:
1743:
1739:
1729:
1726:
1724:
1723:Plasmacytosis
1721:
1719:
1716:
1714:
1711:
1709:
1706:
1704:
1701:
1699:
1696:
1695:
1693:
1691:
1687:
1680:
1679:MALT lymphoma
1676:
1675:
1671:
1668:
1664:
1663:
1659:
1655:
1652:
1651:
1650:
1649:
1645:
1641:
1638:
1636:
1633:
1631:
1628:
1626:
1623:
1622:
1621:
1620:
1616:
1613:
1609:
1608:
1604:
1603:
1601:
1597:
1587:
1586:
1581:
1580:
1578:
1575:
1571:
1566:
1562:
1558:
1551:
1547:
1546:
1542:
1539:
1535:
1532:
1531:
1529:
1526:
1522:
1518:
1514:
1507:
1504:
1502:
1499:
1497:
1494:
1492:
1488:
1487:
1483:
1482:marginal zone
1479:
1478:
1474:
1471:
1469:
1466:
1464:
1461:
1459:
1455:
1454:
1450:
1446:
1445:
1443:
1440:
1436:
1429:
1425:
1424:
1420:
1418:
1415:
1414:
1412:
1409:
1405:
1398:
1394:
1393:
1389:
1386:
1382:
1381:
1377:
1376:
1374:
1371:
1367:
1361:
1357:
1354:
1352:
1350:
1346:
1343:
1335:
1332:
1327:
1324:
1323:
1322:
1316:
1311:
1306:
1302:
1298:
1293:
1289:
1282:
1277:
1275:
1270:
1268:
1263:
1262:
1259:
1255:
1250:
1249:
1245:
1242:
1241:
1231:
1227:
1226:
1222:
1221:
1218:
1214:
1207:
1203:
1202:
1198:
1196:
1192:
1191:
1187:
1185:
1181:
1177:
1176:
1172:
1170:
1166:
1162:
1161:
1157:
1153:
1151:
1147:
1143:
1142:
1138:
1134:
1133:
1130:
1125:
1121:
1114:
1106:
1102:
1096:
1092:
1087:
1086:
1077:
1074:
1070:
1066:
1063:
1058:
1055:
1050:
1048:9783319479064
1044:
1040:
1036:
1032:
1025:
1022:
1017:
1013:
1009:
1005:
1001:
997:
994:(3): 225–37.
993:
989:
982:
980:
978:
976:
974:
970:
965:
961:
957:
953:
949:
945:
938:
935:
930:
926:
922:
918:
913:
908:
904:
900:
896:
892:
888:
881:
878:
873:
869:
865:
861:
857:
853:
849:
845:
837:
834:
829:
825:
820:
815:
810:
805:
801:
797:
793:
786:
783:
778:
774:
770:
766:
762:
758:
754:
750:
743:
740:
735:
729:
725:
718:
715:
710:
706:
701:
696:
692:
688:
684:
680:
673:
666:
663:
658:
654:
649:
644:
640:
636:
631:
626:
622:
618:
614:
607:
604:
600:. 2016-06-02.
599:
593:
590:
583:
579:
576:
574:
571:
570:
566:
564:
562:
557:
555:
551:
543:
541:
539:
530:
527:
525:
521:
518:
516:
513:
510:
507:
504:
500:
497:
493:
490:
488:
485:
482:
479:
477:
474:
472:
471:Photopheresis
469:
467:
464:Conventional
463:
461:
458:
455:
452:
449:
446:
443:
439:
436:
433:
430:
428:
424:
423:
421:
415:
411:
408:
404:
401:
397:
395:
391:
387:
384:
380:
379:
378:
370:
363:
356:
353:
351:
348:
346:
343:
341:
338:
336:
333:
331:
328:
326:
323:
321:
318:
316:
313:
311:
308:
306:
303:
301:
298:
296:
293:
291:
288:
286:
283:
281:
278:
277:
276:
275:
273:
271:
267:
263:
255:
253:
247:
245:
243:
242:dermatophytes
239:
238:
233:
232:
227:
226:
221:
217:
213:
209:
205:
201:
200:
195:
191:
187:
183:
179:
171:
169:
167:
163:
159:
155:
151:
143:
141:
139:
135:
131:
127:
123:
119:
115:
111:
107:
103:
102:immune system
99:
95:
91:
87:
79:
75:
72:
70:
66:
63:
62:H&E stain
59:
55:
51:
46:
41:
33:
19:
3078:Rare cancers
2957:Rural health
2942:Nanomedicine
2493:Rheumatology
2424: /
2343:Hand surgery
2328:Neurosurgery
2066:
2009:
2003:By infection
1884:
1883:
1865:
1826:
1812:
1790:development/
1718:Plasmacytoma
1672:
1660:
1646:
1617:
1605:
1599:By infection
1582:
1543:
1480:
1447:
1421:
1390:
1380:naive B cell
1378:
1339:development/
1253:
1246:
1223:
1199:
1188:
1173:
1154:
1135:
1104:
1084:
1076:
1057:
1030:
1024:
991:
987:
947:
943:
937:
912:1887/3280088
894:
890:
880:
850:(1): 37–44.
847:
843:
836:
799:
795:
785:
752:
748:
742:
723:
717:
682:
678:
665:
620:
616:
606:
592:
558:
547:
544:Epidemiology
535:
487:Methotrexate
483:(Campath-1H)
454:Phototherapy
419:
375:
259:
251:
235:
229:
223:
212:HHV-8 (KSHV)
197:
175:
147:
89:
85:
84:
3027:Wikiproject
2816:Venereology
2761:Neonatology
2658:Dermatology
2513:Gynaecology
2505:gynaecology
2488:Pulmonology
2306:Eye surgery
2268:Specialties
1885:aggressive:
1858:MF+variants
1397:Mantle cell
1392:mantle zone
819:2434/566817
700:2158/311708
509:Gemcitabine
503:doxorubicin
496:Fludarabine
492:Pentostatin
481:Alemtuzumab
476:Interferons
442:nitrosourea
372:Romidepsin
3062:Categories
2789:Psychiatry
2775:(PM&R)
2768:Phlebology
2756:Pediatrics
2583:Anatomical
2548:Diagnostic
2528:Obstetrics
2478:Nephrology
2463:Hematology
2458:Geriatrics
2451:Hepatology
2436:Cardiology
2426:Immunology
1961:peripheral
1458:Follicular
1288:Leukaemias
1201:DiseasesDB
990:(Review).
950:: 76–102.
751:(Review).
584:References
529:Forodesine
522:Allogenic
501:Liposomal
438:Carmustine
432:Bexarotene
407:Romidepsin
400:Vorinostat
390:Bexarotene
166:dermatitis
74:Hematology
58:Micrograph
2977:Physician
2861:education
2719:Neurology
2714:Narcology
2578:Pathology
2556:Radiology
2431:Angiology
2395:Andrology
2096:Lymphoid+
1866:indolent:
1849:Cutaneous
1690:Cutaneous
1468:GCB DLBCL
1463:Burkitt's
1292:lymphomas
1225:eMedicine
929:213450901
639:2234-943X
440:(BCNU, a
414:Poteligeo
364:Treatment
248:Diagnosis
138:spreading
114:cancerous
69:Specialty
3073:Lymphoma
3007:Category
2483:Oncology
2414:medicine
2412:Internal
2260:Medicine
2203:leukemia
1761:leukemia
1756:lymphoma
1315:leukemia
1310:lymphoma
1230:med/3486
1065:Archived
1016:28520647
1008:26923912
964:37307932
921:32412717
872:13571836
864:18212543
828:15692063
777:44407772
769:26602417
709:16310068
657:31106143
567:See also
538:naloxone
511:(Gemzar)
394:retinoid
218:such as
78:oncology
3047:Outline
3017:Commons
2962:Therapy
2859:Medical
2422:Allergy
2390:Urology
2283:Surgery
2191:General
2098:myeloid
2060:T or NK
2031:NK cell
1385:CLL/SLL
1244:DermNet
1195:D016410
1184:M9701/3
1180:M9700/3
1071:website
648:6499168
623:: 300.
548:Of all
505:(Doxil)
412:(2018)
405:(2009)
398:(2006)
388:(2000)
385:(Ontak)
381:(1999)
136:before
122:lesions
112:. The
110:T cells
100:of the
3037:Portal
2904:MD–PhD
2035:(most
2011:HTLV-1
1903:Non-MF
1792:marker
1765:(most
1751:T cell
1423:CD11c+
1341:marker
1319:(most
1305:B cell
1097:
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1014:
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870:
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826:
775:
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730:
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240:, and
214:, and
186:HTLV-2
182:HTLV-1
134:tumors
106:B-cell
98:cancer
2619:Other
1958:Other
1828:CD30+
1574:CD138
1545:CD20+
1439:CD79a
1175:ICD-O
1169:202.2
1165:202.1
1150:C84.1
1146:C84.0
1012:S2CID
925:S2CID
868:S2CID
796:Blood
773:S2CID
675:(PDF)
270:EORTC
208:HHV-7
204:HHV-6
172:Cause
160:, an
130:itchy
2037:CD56
1931:CD30
1910:CD30
1798:TdT+
1742:T/NK
1607:KSHV
1583:see
1570:CD38
1561:PCDs
1525:CD30
1521:CD15
1496:MALT
1408:CD22
1349:TdT+
1326:CD20
1321:CD19
1206:8595
1190:MeSH
1160:9-CM
1095:ISBN
1043:ISBN
1004:PMID
960:PMID
917:PMID
860:PMID
824:PMID
765:PMID
728:ISBN
705:PMID
653:PMID
635:ISSN
126:rash
118:skin
90:CTCL
76:and
2353:ENT
2271:and
2068:EBV
1933:+:
1912:-:
1802:ALL
1777:CD8
1772:CD4
1767:CD3
1662:HIV
1648:HCV
1619:EBV
1523:+,
1370:CD5
1356:ALL
1156:ICD
1137:ICD
1091:283
1035:doi
996:doi
952:doi
948:138
907:hdl
899:doi
852:doi
814:hdl
804:doi
800:105
757:doi
695:hdl
687:doi
643:PMC
625:doi
266:WHO
190:HIV
152:or
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1800::
1788:By
1576:+)
1572:+/
1565:PP
1527:+)
1517:RS
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