258:
168:
41:
2842:
399:
2853:
653:
of the lower-dosed monkeys were found to have malignant cancer, each with a different kind of cancer, and three benign tumors were found. The authors concluded that the study failed to demonstrate that cyclamate was carcinogenic because the cancers were all different and there was no way to link cyclamate to each of them. The substance did not show any DNA-damaging properties in DNA repair assays.
2873:
402:
2883:
2832:
2863:
404:
450:
625:, removed the GRAS designation from cyclamate and banned its use in general-purpose foods, though it remained available for restricted use in dietary products with additional labeling; in October 1970, the FDA, under a new commissioner, banned cyclamate completely from all food and drug products in the United States.
403:
1184:
Are there any high-intensity sweeteners that are currently prohibited by FDA for use in the United States but are used in other countries? Yes. Cyclamates and its salts (such as calcium cyclamate, sodium cyclamate, magnesium cyclamate, and potassium cyclamate) are currently prohibited from use in the
652:
In 2000, a paper was published describing the results of a 24-year-long experiment in which 16 monkeys were fed a normal diet and 21 monkeys were fed either 100 or 500 mg/kg cyclamate per day; the higher dose corresponds to about 30 cans of a diet beverage. Two of the high-dosed monkeys and one
539:
Prior to 1973, Abbott
Laboratories produced sodium cyclamate (Sucaryl) by a mixture of ingredients including the addition of pure sodium (flakes or rods suspended in solvent) with cyclohexylamine, chilled and filtered through a high speed centrifugal separator, dried, granulated and micro-pulverised
2462:
1201:
628:
Abbott
Laboratories claimed that its own studies were unable to reproduce the 1969 study's results, and, in 1973, Abbott petitioned the FDA to lift the ban on cyclamate. This petition was eventually denied in 1980 by FDA Commissioner
591:. Cyclamate was marketed in tablet form for use by diabetics as an alternative tabletop sweetener, as well as in a liquid form. As cyclamate is stable to heat, it was and is marketed as suitable for use in cooking and baking.
661:
Cyclamate is approved as a sweetener in at least 130 countries. In the late 1960s, cyclamate was banned in the United
Kingdom; however, it was approved after being re-evaluated by the European Union in 1996.
606:. The released study was showing that eight out of 240 rats fed a mixture of saccharin and cyclamates, at levels equivalent to humans ingesting 550 cans of diet soda per day, developed bladder tumors.
609:
Sales continued to expand, and in 1969, annual sales of cyclamate had reached $ 1 billion, which increased pressure from public safety watchdogs to restrict the usage of cyclamate. In
October 1969,
1197:
598:, a compound suspected to have some chronic toxicity in animals. Further research resulted in a 1969 study that found the common 10:1 cyclamate–saccharin mixture increased the incidence of
2625:
940:
610:
862:
2590:
641:
representing the diet foods industry), filed a second petition in 1982. Although the FDA has stated that a review of all available evidence does not implicate cyclamate as a
1511:
463:
1171:
2620:
2076:
1009:
2580:
968:
575:, which undertook the necessary studies and submitted a New Drug Application in 1950. Abbott intended to use cyclamate to mask the bitterness of certain drugs such as
405:
497:; the mixture of 10 parts cyclamate to 1 part saccharin is common and masks the off-tastes of both sweeteners. It is less expensive than most sweeteners, including
649:, though not actively considered. It is unclear whether this is at the request of Abbott Labs or because the petition is considered to be insufficient by the FDA.
549:
1757:
413:
2512:
2765:
2479:
307:
2703:
2919:
670:
1145:
493:(table sugar), making it the least potent of the commercially used artificial sweeteners. It is often used with other artificial sweeteners, especially
2541:
2585:
2447:
2555:
427:
1504:
2399:
2546:
2494:
1455:
2886:
2749:
2560:
2489:
2414:
2233:
1484:
1085:
933:
2737:
2615:
854:
673:
lifted the ban in 2013, declaring it safe for consumption. Cyclamate remains banned in the United States, South Korea, and
Bangladesh.
501:, and is stable under heating. Safety concerns led to it being banned in a few countries, though the European Union considers it safe.
1750:
614:
420:
105:
2959:
2754:
2713:
2678:
2663:
2645:
2570:
2349:
1497:
1234:
1121:
893:
837:
800:
767:
272:
3008:
2759:
2595:
2526:
2521:
2698:
2605:
2469:
2384:
2147:
1167:
999:
3184:
2912:
2727:
2600:
2437:
2404:
1369:
3179:
3013:
2503:
2457:
1893:
1743:
1693:
1198:"Substances Added to Food (formerly Everything Added to Food in the United States (EAFUS)), Search Criteria = "cyclamate""
825:
3159:
2732:
1004:
618:
588:
584:
215:
1302:
3189:
2786:
2484:
2442:
1796:
236:
1250:
3169:
2781:
1399:
470:
3174:
3079:
2993:
2905:
2811:
2531:
1705:
3084:
2673:
2034:
2026:
1869:
645:
in mice or rats, cyclamate remains banned from food products in the United States. The petition is now held in
956:
approval of cyclamate for use as a sweetening agent in food and for technological purposes in food is denied.
634:
2653:
2565:
2006:
1881:
1137:
982:
2866:
163:
3138:
2721:
2641:
2536:
2359:
2238:
1429:
564:
down on the lab bench, and when he put it back in his mouth, he discovered the sweet taste of cyclamate.
125:
2743:
2693:
2688:
2432:
2180:
1616:
1343:
1274:
40:
2978:
2856:
2170:
1999:
1854:
1645:
486:
53:
3164:
2872:
2816:
2575:
2273:
622:
572:
553:
253:
71:
1451:
2474:
2427:
2369:
2253:
1925:
1321:
594:
In 1966, a study reported that some intestinal bacteria could desulfonate cyclamate to produce
3064:
2801:
2610:
2296:
1930:
1915:
1897:
1811:
1571:
1548:
1230:
1117:
1111:
1078:
1060:
962:
910:
889:
833:
796:
763:
757:
721:
Rio (Produced under license and authority of SweetLife AG Switzerland by SweetLife Ltd, China)
1224:
829:
818:
784:
3117:
3038:
2970:
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2364:
2344:
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1778:
1657:
1629:
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1554:
1050:
517:
330:
224:
3101:
3091:
3069:
3059:
2668:
2374:
2336:
2306:
2152:
2085:
1950:
1935:
1859:
1826:
1306:
595:
533:
525:
145:
81:
257:
167:
2935:
2791:
1955:
1920:
1816:
682:
599:
441:
3153:
3074:
2796:
2316:
2124:
1985:
1965:
1876:
1841:
1636:
1622:
1610:
1587:
1558:
1532:
715:
Hermesetas (Switzerland, incl. UK market) in mini tablet, granulated, and liquid form
690:
580:
529:
521:
156:
3096:
2846:
2806:
2321:
2142:
2134:
2104:
1975:
1960:
1806:
1538:
1479:
281:
InChI=1S/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
1365:
291:
InChI=1/C6H13NO3S.Na/c8-11(9,10)7-6-4-2-1-3-5-6;/h6-7H,1-5H2,(H,8,9,10);/q;+1/p-1
204:
3133:
2876:
2836:
2422:
2379:
2311:
2291:
2268:
2243:
2047:
2042:
2020:
2013:
1970:
1940:
1910:
1766:
1544:
666:
576:
557:
820:
Processed foods and the consumer: additives, labeling, standards, and nutrition
3023:
2637:
2389:
2354:
2283:
2070:
1945:
1905:
1774:
642:
630:
367:
136:
1022:
FAP 2A3672 Cyclamate (cyclamic acid, calcium cyclamate, and sodium cyclamate)
3043:
3033:
3028:
2988:
2683:
2394:
2326:
2301:
2263:
2228:
2220:
2202:
2187:
2175:
2119:
2096:
2064:
2059:
1849:
1687:
1675:
1669:
1651:
1581:
1299:
1055:
1038:
561:
498:
494:
1064:
524:(cyclohexanesulfamic acid), which itself is prepared by reacting freebase
17:
2658:
2248:
2197:
2053:
1993:
1821:
1791:
1717:
1711:
1562:
1520:
697:
646:
638:
426:
419:
412:
385:
183:
175:
1391:
3018:
2983:
2943:
2114:
1831:
1801:
1735:
1723:
1699:
1681:
1663:
514:
490:
191:
2831:
1392:"SugarTwin - Artificial Sweeteners - Sugar Substitutes - Calorie Free"
3003:
2998:
2258:
2216:
1786:
932:
Goyan, Jere E., Commissioner of Food and Drugs. (September 4, 1980).
686:
568:
510:
116:
1489:
440:
Except where otherwise noted, data are given for materials in their
2897:
2212:
1864:
104:
94:
2901:
1739:
1493:
2109:
1604:
1421:
603:
1278:
241:
1568:
1335:
1039:"Artificial sweeteners—do they bear a carcinogenic risk?"
397:
1113:
Chemistry and
Technology of Soft Drinks and Fruit Juices
939:. Office of the Federal Register. pp. 61474–61530.
888:. London, England: Portobello books. pp. 143–144.
855:"Michael Sveda, the Inventor Of Cyclamates, Dies at 87"
458:
556:. Sveda was working in the lab on the synthesis of an
1485:
FDA Commissioner's
Decision on Cyclamate, 45 FR 61474
689:
contain cyclamate, though not those produced for the
176:
1480:
European
Commission Revised Opinion On Cyclamic Acid
3126:
3110:
3052:
2968:
2952:
2933:
2774:
2712:
2636:
2591:
2024 United
Kingdom Shigatoxigenic E. coli outbreak
2413:
2335:
2282:
2211:
2161:
2133:
2095:
1984:
1892:
1840:
1773:
1170:. U.S. Food and Drug Administration. May 19, 2014.
817:
934:"Cyclamate, Commissioner's Decision, 45 FR 61474"
203:
1138:"FDA lifts ban on 'magic sugar' - Philstar.com"
401:
80:
789:Encyclopedia of Chemical Processing and Design
2913:
1751:
1505:
706:Chuker (Argentina) – Merisant Company 2, SARL
611:Department of Health, Education & Welfare
8:
2766:Spanish Agency for Food Safety and Nutrition
2581:2017–2018 South African listeriosis outbreak
2480:1985 Austrian diethylene glycol wine scandal
967:: CS1 maint: multiple names: authors list (
756:Jim Smith, Lily Hong-Shum (April 15, 2008).
2704:United Kingdom food information regulations
2920:
2906:
2898:
1758:
1744:
1736:
1512:
1498:
1490:
567:The patent for cyclamate was purchased by
256:
166:
144:
28:
2542:2008 United States salmonellosis outbreak
1054:
983:"FDA Talk Paper, NAS Report on Cyclamate"
223:
2586:2018 Australian strawberry contamination
2448:Morinaga Milk arsenic poisoning incident
548:Cyclamate was discovered in 1937 at the
2556:2011 United States listeriosis outbreak
865:from the original on September 12, 2017
748:
671:Philippine Food and Drug Administration
312:
277:
252:
2571:2015 Mozambique funeral beer poisoning
2148:Ethylenediaminetetraacetic acid (EDTA)
1458:from the original on November 27, 2022
1116:. John Wiley & Sons. p. 247.
1032:
1030:
1000:"Petitions Currently Held in Abeyance"
960:
762:. John Wiley & Sons. p. 960.
157:
1402:from the original on January 16, 2022
1346:from the original on December 6, 2011
1200:. U.S. Food and Drug Administration.
1110:Ashurst, Philip R. (April 15, 2008).
1091:from the original on February 4, 2022
1012:from the original on February 8, 2015
783:McKetta Jr, John J. (June 19, 1996).
284:Key: UDIPTWFVPPPURJ-UHFFFAOYSA-M
124:
7:
2862:
2750:Institute for Food Safety and Health
2490:Australian meat substitution scandal
2458:Moroccan oil poisoning disaster 1959
2234:Arsenic contamination of groundwater
1432:from the original on October 9, 2021
1204:from the original on October 2, 2022
2882:
2738:Food Information and Control Agency
1223:Newton, David E (January 1, 2009).
1174:from the original on April 23, 2019
946:from the original on April 12, 2015
853:Kaufman, Leslie (August 21, 1999).
583:. In 1958, it was designated GRAS (
294:Key: UDIPTWFVPPPURJ-REWHXWOFAV
194:
1372:from the original on June 29, 2015
25:
2960:Acid-hydrolyzed vegetable protein
2755:International Food Safety Network
2679:International Food Safety Network
2400:Variant Creutzfeldt–Jakob disease
2350:Acid-hydrolyzed vegetable protein
2077:Shigatoxigenic and verotoxigenic
1598:Additional chemicals (E1100–1599)
1148:from the original on May 15, 2022
669:, cyclamate was banned until the
633:. Abbott Labs, together with the
489:. It is 30–50 times sweeter than
3009:Hydrogenated starch hydrolysates
2881:
2871:
2861:
2852:
2851:
2840:
2830:
2760:Ministry of Food and Drug Safety
2596:Kobayashi red yeast rice scandal
2527:2008 Canada listeriosis outbreak
2522:ICA meat repackaging controversy
448:
348:
342:
39:
2699:Quality Assurance International
2606:Food safety incidents in Taiwan
2576:2017 Brazil Operation Weak Meat
2470:1971 Iraq poison grain disaster
2385:Polycyclic aromatic hydrocarbon
1079:"Worldwide Status of Cyclamate"
444:(at 25 °C , 100 kPa).
2953:Artificial protein substitutes
2728:European Food Safety Authority
2601:Food safety incidents in China
2438:1858 Bradford sweets poisoning
2405:Water fluoridation controversy
1037:Weihrauch MR, Diehl V (2004).
712:Huxol (Germany) in liquid form
360:
354:
351:
336:
1:
3014:Neohesperidin dihydrochalcone
1694:Neohesperidin dihydrochalcone
826:University of Minnesota Press
2733:Food and Drug Administration
2415:Food contamination incidents
1229:. Infobase. pp. 73–77.
1005:Food and Drug Administration
909:Chedd, Grahm (May 9, 1974).
785:"Sweeteners, High Intensity"
619:Food and Drug Administration
589:Food and Drug Administration
585:Generally Recognized as Safe
540:for powder or tablet usage.
2787:Food and drink prohibitions
2561:Bihar school meal poisoning
2485:United Kingdom BSE outbreak
2443:1900 English beer poisoning
1797:Antibiotic use in livestock
1168:"High-Intensity Sweeteners"
1084:. Calorie Control Council.
816:Packard, Vernal S. (1976).
3206:
2782:Curing (food preservation)
1855:Monosodium glutamate (MSG)
911:"The Search for Sweetness"
58:Sodium cyclohexylsulfamate
2994:Aspartame-acesulfame salt
2825:
2812:Genetically modified food
2664:Food labeling regulations
2532:2008 Chinese milk scandal
1706:Aspartame-acesulfame salt
1528:
438:
379:
323:
303:
268:
64:
52:
47:
38:
3053:Natural food substitutes
2674:Food safety in Australia
1870:High-fructose corn syrup
1594:Miscellaneous (E900–999)
1251:
759:Food Additives Data Book
2654:Acceptable daily intake
2566:2013 horse meat scandal
2007:Clostridium perfringens
1422:"Sugromax :: Home"
703:Cap Cangkir (Indonesia)
681:Sweeteners produced by
635:Calorie Control Council
587:) by the United States
3139:List of food additives
2722:Centre for Food Safety
2537:2008 Irish pork crisis
2239:Benzene in soft drinks
886:The Case against Sugar
736:Sugromax (New Zealand)
550:University of Illinois
408:
3185:Suspected carcinogens
2744:Food Standards Agency
2694:Organic certification
2689:Nutrition facts label
2433:Esing Bakery incident
2221:environment pollution
1305:July 1, 2007, at the
1056:10.1093/annonc/mdh256
884:Taubes, Gary (2017).
700:(Switzerland, Brazil)
407:
184:(glazing agents, ...)
3180:Cyclohexyl compounds
2979:Acesulfame potassium
2513:2006 North American
2171:Acesulfame potassium
2000:Campylobacter jejuni
1894:Intestinal parasites
1767:Consumer food safety
744:Notes and references
733:Sweet'n Low (Canada)
552:by graduate student
487:artificial sweetener
390:(fire diamond)
54:Preferred IUPAC name
3160:Abbott Laboratories
2817:Conspiracy theories
2370:Heterocyclic amines
2274:Shellfish poisoning
1275:"Tastes like sugar"
739:El Dorra (Tunisia)
727:Sugar Twin (Canada)
685:and Sugar Twin for
623:Herbert L. Ley, Jr.
573:Abbott Laboratories
375: g·mol
315:.O=S()(=O)NC1CCCCC1
35:
3190:E-number additives
3065:Coffee substitutes
2475:Toxic oil syndrome
2428:Swill milk scandal
2254:Diethylstilbestrol
1926:Diphyllobothriasis
1549:acidity regulators
1300:Assugrin's website
718:Novasweet (Russia)
571:and later sold to
471:Infobox references
409:
33:(Sodium cyclamate)
29:
3170:Sugar substitutes
3147:
3146:
2971:sugar substitutes
2895:
2894:
2802:Food preservation
2611:Foodborne illness
2163:Sugar substitutes
1916:Cryptosporidiosis
1898:parasitic disease
1812:HGH controversies
1779:food contaminants
1733:
1732:
1582:Flavour enhancers
1576:anticaking agents
730:Suitli (Bulgaria)
560:drug. He put his
509:Cyclamate is the
479:Chemical compound
477:
476:
237:CompTox Dashboard
106:Interactive image
16:(Redirected from
3197:
3175:Sodium compounds
3102:Salt substitutes
3092:Milk substitutes
3060:Cheese analogues
3039:Sodium cyclamate
2928:Artificial foods
2922:
2915:
2908:
2899:
2885:
2884:
2875:
2865:
2864:
2855:
2854:
2847:Drink portal
2845:
2844:
2843:
2835:
2834:
2746:(United Kingdom)
2495:Jack in the Box
2466:
2453:Minamata disease
2365:Food irradiation
2345:4-Hydroxynonenal
2193:Sodium cyclamate
2036:Escherichia coli
2028:Escherichia coli
1760:
1753:
1746:
1737:
1617:Improving agents
1611:Synthetic glazes
1514:
1507:
1500:
1491:
1468:
1467:
1465:
1463:
1448:
1442:
1441:
1439:
1437:
1418:
1412:
1411:
1409:
1407:
1388:
1382:
1381:
1379:
1377:
1362:
1356:
1355:
1353:
1351:
1332:
1326:
1325:
1318:
1312:
1311:
1297:
1291:
1290:
1288:
1286:
1281:on July 10, 2017
1277:. Archived from
1271:
1265:
1264:
1262:
1260:
1247:
1241:
1240:
1220:
1214:
1213:
1211:
1209:
1194:
1188:
1187:
1181:
1179:
1164:
1158:
1157:
1155:
1153:
1134:
1128:
1127:
1107:
1101:
1100:
1098:
1096:
1090:
1083:
1075:
1069:
1068:
1058:
1034:
1025:
1024:
1019:
1017:
996:
990:
989:
987:
979:
973:
972:
966:
958:
953:
951:
945:
938:
929:
923:
922:
906:
900:
899:
881:
875:
874:
872:
870:
850:
844:
843:
823:
813:
807:
806:
780:
774:
773:
753:
461:
455:
452:
451:
429:
422:
415:
400:
374:
362:
356:
353:
350:
344:
338:
331:Chemical formula
261:
260:
245:
243:
227:
207:
196:
178:
170:
159:
148:
128:
108:
84:
43:
36:
34:
21:
3205:
3204:
3200:
3199:
3198:
3196:
3195:
3194:
3150:
3149:
3148:
3143:
3122:
3106:
3070:Egg substitutes
3048:
2964:
2948:
2936:fat substitutes
2929:
2926:
2896:
2891:
2841:
2839:
2837:Food portal
2829:
2821:
2770:
2708:
2669:Food libel laws
2632:
2460:
2409:
2375:Modified starch
2337:Food processing
2331:
2278:
2207:
2157:
2153:Sodium benzoate
2129:
2091:
2086:Vibrio cholerae
1980:
1951:Gnathostomiasis
1936:Fasciolopsiasis
1888:
1836:
1827:Mercury in fish
1769:
1764:
1734:
1729:
1642:
1623:Packaging gases
1601:
1524:
1518:
1476:
1471:
1461:
1459:
1450:
1449:
1445:
1435:
1433:
1420:
1419:
1415:
1405:
1403:
1390:
1389:
1385:
1375:
1373:
1364:
1363:
1359:
1349:
1347:
1334:
1333:
1329:
1320:
1319:
1315:
1309:
1307:Wayback Machine
1298:
1294:
1284:
1282:
1273:
1272:
1268:
1258:
1256:
1253:
1249:
1248:
1244:
1237:
1222:
1221:
1217:
1207:
1205:
1196:
1195:
1191:
1177:
1175:
1166:
1165:
1161:
1151:
1149:
1136:
1135:
1131:
1124:
1109:
1108:
1104:
1094:
1092:
1088:
1081:
1077:
1076:
1072:
1036:
1035:
1028:
1015:
1013:
998:
997:
993:
985:
981:
980:
976:
959:
949:
947:
943:
936:
931:
930:
926:
908:
907:
903:
896:
883:
882:
878:
868:
866:
852:
851:
847:
840:
824:. Minneapolis:
815:
814:
810:
803:
782:
781:
777:
770:
755:
754:
750:
746:
679:
659:
596:cyclohexylamine
546:
534:sulfur trioxide
526:cyclohexylamine
507:
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466: ?)
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1340:novaprodukt.ru
1327:
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1966:Toxoplasmosis
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1452:"Labo-arrazi"
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1336:"Новапродукт"
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1123:9781405141086
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915:New Scientist
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895:9781846276378
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839:0-8166-0778-8
835:
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802:9780824726072
798:
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769:9781405172417
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691:United States
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637:(a political
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621:Commissioner
620:
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601:
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592:
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582:
581:pentobarbital
578:
574:
570:
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563:
559:
555:
554:Michael Sveda
551:
543:
541:
537:
535:
531:
530:sulfamic acid
527:
523:
522:cyclamic acid
519:
516:
512:
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254:DTXSID6020355
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158:ECHA InfoCard
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63:
55:
51:
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42:
37:
27:
19:
3097:Phyllodulcin
2807:Food quality
2714:Institutions
2548:
2514:
2505:
2496:
2380:Nitrosamines
2143:Benzoic acid
2105:Chlorpyrifos
2084:
2078:
2069:
2052:
2035:
2027:
2019:
2012:
2005:
1998:
1976:Trichuriasis
1961:Toxocariasis
1931:Enterobiasis
1807:Formaldehyde
1646:Acesulfame K
1628:
1593:
1545:Antioxidants
1460:. Retrieved
1446:
1434:. Retrieved
1425:
1416:
1404:. Retrieved
1395:
1386:
1376:November 26,
1374:. Retrieved
1360:
1350:November 27,
1348:. Retrieved
1339:
1330:
1322:"Hermesetas"
1316:
1295:
1283:. Retrieved
1279:the original
1269:
1257:. Retrieved
1245:
1225:
1218:
1206:. Retrieved
1192:
1183:
1176:. Retrieved
1162:
1150:. Retrieved
1142:philstar.com
1141:
1132:
1112:
1105:
1095:November 23,
1093:. Retrieved
1073:
1046:
1042:
1021:
1014:. Retrieved
1003:
994:
977:
955:
948:. Retrieved
927:
918:
914:
904:
885:
879:
869:February 20,
867:. Retrieved
858:
848:
819:
811:
792:
788:
778:
758:
751:
680:
664:
660:
657:Legal status
651:
627:
617:, bypassing
615:Robert Finch
608:
593:
566:
547:
538:
528:with either
508:
482:
481:
386:
126:ChEMBL273977
65:Identifiers
26:
3134:Food safety
2969:Artificial
2934:Artificial
2887:WikiProject
2724:(Hong Kong)
2461: [
2423:Devon colic
2297:Breast milk
2269:Nonylphenol
2244:Bisphenol A
2181:controversy
2048:Hepatitis E
2043:Hepatitis A
2021:Enterovirus
2014:Cronobacter
1971:Trichinosis
1941:Fasciolosis
1911:Anisakiasis
1882:controversy
1775:Adulterants
1588:Antibiotics
1563:emulsifiers
1559:stabilisers
1406:January 16,
1310:(in French)
1285:November 1,
1255:(in Korean)
1208:February 8,
1178:February 8,
1016:February 8,
950:February 8,
921:(897): 299.
828:. pp.
683:Sweet'n Low
667:Philippines
577:antibiotics
558:antipyretic
324:Properties
164:100.004.863
3165:Sulfamates
3154:Categories
3024:NutraSweet
2638:Regulation
2621:death toll
2390:Shortening
2355:Acrylamide
2284:Food fraud
2264:Mycotoxins
2097:Pesticides
2071:Salmonella
1946:Giardiasis
1906:Amoebiasis
1850:Flavorings
1639:(E990–999)
1632:(E950–969)
1630:Sweeteners
1625:(E930–949)
1619:(E920–929)
1613:(E910–919)
1607:(E900–909)
1590:(E700–799)
1584:(E600–699)
1578:(E500–599)
1572:regulators
1565:(E400–499)
1555:Thickeners
1551:(E300–399)
1541:(E200–299)
1535:(E100–199)
1436:October 9,
1396:Sugar Twin
1259:August 23,
643:carcinogen
631:Jere Goyan
613:Secretary
368:Molar mass
225:1I6F42RME1
137:ChemSpider
93:3D model (
72:CAS Number
30:Cyclamate
18:Cyclamates
3044:Sucralose
3034:Saccharin
3029:Nutrinova
2989:Aspartame
2684:ISO 22000
2646:watchdogs
2642:standards
2616:outbreaks
2517:outbreaks
2395:Trans fat
2307:Olive oil
2229:Aflatoxin
2203:Sucralose
2188:Saccharin
2176:Aspartame
2120:Malathion
2065:Rotavirus
2060:Norovirus
1688:Thaumatin
1676:Sucralose
1670:Saccharin
1658:Cyclamate
1652:Aspartame
1521:E numbers
1366:"Sucaryl"
1252:사이클라민산나트륨
1152:April 16,
1043:Ann Oncol
562:cigarette
505:Chemistry
499:sucralose
495:saccharin
483:Cyclamate
182:E952(iv)
2877:Cookbook
2857:Category
2659:E number
2551:outbreak
2508:outbreak
2499:outbreak
2249:Dieldrin
2198:Sorbitol
2054:Listeria
1994:Botulism
1822:Melamine
1792:Aldicarb
1718:Lactitol
1712:Maltitol
1456:Archived
1430:Archived
1426:Sugromax
1400:Archived
1370:Archived
1344:Archived
1303:Archived
1202:Archived
1172:Archived
1146:Archived
1086:Archived
1065:15367404
1010:Archived
963:cite web
941:Archived
863:Archived
709:Cologran
698:Assugrin
647:abeyance
387:NFPA 704
380:Hazards
177:E number
82:139-05-9
3019:Neotame
2984:Alitame
2944:Olestra
2867:Commons
2740:(Spain)
2549:E. coli
2515:E. coli
2506:E. coli
2497:E. coli
2317:Seafood
2217:poisons
2115:Lindane
2079:E. coli
2038:O157:H7
2030:O104:H4
1832:Sudan I
1802:Cyanide
1724:Xylitol
1700:Neotame
1682:Alitame
1664:Isomalt
1533:Colours
1523:950–969
724:Sucaryl
665:In the
544:History
515:calcium
491:sucrose
464:what is
462: (
192:PubChem
3111:Brands
3004:Glucin
2999:Dulcin
2322:Shrimp
2259:Dioxin
2213:Toxins
1787:3-MCPD
1726:(E967)
1720:(E966)
1714:(E965)
1708:(E962)
1702:(E961)
1696:(E959)
1690:(E957)
1684:(E956)
1678:(E955)
1672:(E954)
1666:(E953)
1660:(E952)
1654:(E951)
1648:(E950)
1574:&
1561:&
1547:&
1462:May 5,
1233:
1120:
1063:
892:
836:
799:
795:: 72.
766:
687:Canada
677:Brands
569:DuPont
511:sodium
485:is an
459:verify
456:
373:201.22
308:SMILES
117:ChEMBL
48:Names
3080:bacon
2465:]
2312:Prawn
2292:Bread
1865:Sugar
1605:Waxes
1089:(PDF)
1082:(PDF)
986:(PDF)
944:(PDF)
937:(PDF)
639:lobby
273:InChI
95:JSmol
3118:Tang
3085:list
1860:Salt
1464:2023
1438:2021
1408:2022
1378:2014
1352:2011
1287:2010
1261:2018
1231:ISBN
1210:2015
1180:2015
1154:2013
1118:ISBN
1097:2018
1061:PMID
1018:2015
969:link
952:2015
890:ISBN
871:2017
834:ISBN
797:ISBN
764:ISBN
604:rats
579:and
518:salt
216:UNII
205:8751
146:8421
2327:Tea
2302:Egg
2110:DDT
1051:doi
830:332
602:in
532:or
520:of
513:or
242:EPA
195:CID
3156::
2644:,
2640:,
2463:ar
2219:,
2215:,
1896:,
1777:,
1569:pH
1557:,
1454:.
1428:.
1424:.
1398:.
1394:.
1368:.
1342:.
1338:.
1182:.
1144:.
1140:.
1059:.
1047:15
1045:.
1041:.
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1020:.
1008:.
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965:}}
961:{{
954:.
919:62
917:.
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861:.
857:.
832:.
793:56
791:.
787:.
693:.
536:.
352:Na
346:12
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2914:t
2907:v
1759:e
1752:t
1745:v
1513:e
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1499:v
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1440:.
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1380:.
1354:.
1324:.
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1263:.
1239:.
1212:.
1156:.
1126:.
1099:.
1067:.
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988:.
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842:.
805:.
772:.
454:N
428:0
421:1
414:2
361:S
358:3
355:O
349:N
343:H
340:6
337:C
244:)
240:(
97:)
20:)
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