244:
221:
118:
143:
1131:, glucose stimulation leads to the remodeling of microtubules responsible for insulin secretion. CAMSAP2 binds to the minus ends of microtubules in normal clonal cells. The knockdown of CAMSAP2 in the β-cells reduces the total insulin content secreted through glucose-stimulated insulin secretion. CAMSAP2 localizes to the Golgi apparatus instead of the microtubule minus ends. The oddity is observed only in β-cells as opposed to
250:
149:
1168:
1067:
1228:). The phenomenon sees the existence of free minus and plus-ends throughout the cell. CAMSAP2 has an affinity for binding to free microtubule minus ends in the cell. The stabilization CAMSAP2 can achieve by binding to the free ends of the microtubules is important in regulating neuronal polarity. The highly polarized neurons are formed in the developing neocortex, and the
1261:. All of the microtubule-based tracks in Sertoli cells are crucial for the intracellular transport of organelles. CAMSAP2 is bound to the minus-ends of microtubules, slowing down the polymerization of free tubulins and effectively regulating their growth. By knocking down CAMSAP2 proteins in these regions, the growth of the tracks could support
1118:
to achieve the organization observed in the non-centrosomal microtubules. They possess the ability to suppress the organization of microtubules by the centrosome, and the specific family of proteins is important for the suitable arrangement of organelles in the cell body. The proteins gathered at the
1194:
process; however, CAMSAP2 can act as a strong nucleating agent for microtubule formation independent of the γ-tubulin. CAMSAP2 significantly reduces the nucleation energy barrier by stabilizing longitudinal interactions between the αβ-tubulin dimers, thereby increasing the critical concentration for
1062:
proteins are responsible for microtubule stability which are not required for the Golgi tethering. When no centromeres are present, AKAP9 and CAMSAP-2 dependent pathways of the microtubule minus ends become a dominant force and must exist in order to observe the maintenance of microtubule density.
1045:
domains, which function as molecular spacers. CAMSAP2 acts as a microtubule minus-end anchor and binds microtubules through its CKK domain. CAMSAP2 is necessary for the proper organization and stabilization of interphase microtubules. The protein also plays a role in cell migration. CAMSAP2
1232:
loses its function as an MTOC. CAMSAP2 structures' stability-providing qualities ensure the fate of the axon and the development of neuronal polarity needed for neocortex development. Neurons lacking CAMSAP2 fail to begin axon formation and lack neuronal polarization.
1290:. When placed in an assay of liver samples, an outgrowth of HCC cells was observed. Upon the depletion of CAMSAP2 from the samples, a drop in the prevalence of acetylated microtubules occurred. CAMSAP2 exhibited tumor-suppressing qualities by downregulating the
1346:
An association between CAMSAP2 expression levels and the progression and prognosis of gastric cancer was investigated in 2023. The investigation into the expression of the CAMSAP2 protein in gastric cancer aimed to understand its effects on cell invasion and
1091:
that binds to microtubules. The specific CKK domain is a defining factor of the CAMSAP protein family. It enables CAMSAP2 to recognize and bind to microtubule minus ends and allows CAMSAP2 to decorate and stabilize the microtubule lattice formed by minus-end
1338:, regulated the invasion of the cells and slowed down disease progress. Metastasis of colorectal cancer permeates through the activation of the signaling pathway and indicates CAMSAP2 as a promising target for treating metastatic colorectal cancer patients.
1113:
CAMSAP2 proteins are observed to be primarily responsible for the maintenance of non-centrosomal microtubules. In epithelial cells, major microtubules are not anchored to the centrosome, which can be observed in other cell types. CAMSAP2 cooperates with
1680:
1135:. With the specific collection at the Golgi apparatus, CAMSAP2 promotes the protein trafficking of the Golgi, efficiently facilitating the process. Without CAMSAP2, there would not be adequate insulin production for secretion from the β-cells.
2088:
1086:
with structurally and functionally different ends. There exists a plus-end and a minus-end on each microtubule. The CAMSAP family of proteins contributes to regulating the minus-ends of microtubules. CAMSAP2 contains a
1147:. CAMSAP2 is required for the proper organization of non-centrosomal interphase molecules. Depletion of CAMSAP2 leads to a mostly centrosome-anchored, radial microtubule array. CAMSAP2 is responsible for
1041:. CAMSAP2 possesses a microtubule-binding domain near the C-terminal region where "microtubule interactions" occur. On the C-terminal regions, protein to protein interactions are accelerated by three
1269:
of the CAMSAP2 promoted
Sertoli cell tight junction barrier function, which suggests its role in tight junction remodeling. CAMSAP2 knockdown blocked the disruptive organization of microtubules and
1155:, CAMSAP2 depletion reduced the ability of cells to close a wound, indicating impaired directional migration. CAMSAP2 populates the cytoplasm with microtubules, allowing the cell to regenerate its
1151:
because the stretches of CAMSAP2-decorated microtubules enable proper microtubule organization to achieve spatial redistribution and functional specialization of components in the cell. In
1088:
257:
156:
1119:
minus ends of the non-centrosomal microtubules can stabilize them. Without these proteins, the Golgi apparatus would exhibit irregular distributions of the microtubules.
2625:
1580:
739:
720:
79:
1355:, and they analyzed the expression levels of CAMSAP2 proteins. Gastric cancer MGC803 cells with CAMSAP2 overexpression and knockdown were studied for
1630:
1253:. The protein was found throughout the Sertoli cell cytosol colocalized with microtubules. The Sertoli cells are responsible for regulating the
1356:
1504:
1486:
3253:
1334:, CAMSAP2 promotes the capabilities of migration in colorectal cells. Through the silencing of the gene, the substantial downstream target,
4940:
1379:
results. The scientists discovered that gastric cancer tissues demonstrated high levels of CAMSAP2. The results positively correlated with
2618:
1732:"AlphaFold Protein Structure Database: massively expanding the structural coverage of protein-sequence space with high-accuracy models"
971:
243:
1410:. The high expression of CAMSAP2 contributes to gastric cancer progression and poor prognosis by the upregulation of TGF-β signaling.
978:
1769:
1286:
CAMSAP2 plays a role in the migration of cancer cells. It has been observed that CAMSAP2 is severely upregulated in cancers such as
220:
1257:. CAMSAP2 appears along the seminiferous epithelium close to the basement membrane. It increases the function of the Sertoli cell
1171:
Nucleation and aster formation activity of CAMSAP2. Observe the microtubule projections from the black dots (CAMSAP2 complexes).
3772:
2467:"[High expression of CAMSAP2 promotes invasion and metastasis of gastric cancer cells by upregulating TGF-β signaling]"
1473:
1452:
1245:
function. Sertoli cells are intrinsically polarized, with minus ends pointing toward the tubule lumen and plus ends toward the
4041:
3884:
2611:
2150:
Imasaki T, Kikkawa S, Niwa S, Saijo-Hamano Y, Shigematsu H, Aoyama K, et al. (June 2022). Carter AP, Pfeffer SR (eds.).
1920:
1469:
142:
117:
4920:
4474:
1448:
2407:"CAMSAP2 promotes colorectal cancer cell migration and invasion through activation of JNK/c-Jun/MMP-1 signaling pathway"
59:
1523:"CAMSAP2 calmodulin regulated spectrin associated protein family member 2 [Homo sapiens (human)] - Gene - NCBI"
256:
155:
3181:
1709:
1530:
2298:"CAMSAP2 Is a Microtubule Minus-End Targeting Protein That Regulates BTB Dynamics Through Cytoskeletal Organization"
249:
148:
4652:
1395:
1250:
1254:
4885:
2384:
1383:
1323:
1319:
1303:
1287:
1183:
1097:
784:
67:
4945:
765:
1186:. Microtubule nucleation normally requires overcoming a large energy barrier inside of cells. Typically, a
1176:
3304:
2658:
1984:"Nezha/CAMSAP3 and CAMSAP2 cooperate in epithelial-specific organization of noncentrosomal microtubules"
1602:
1360:
1196:
2252:
Yau KW, van
Beuningen SF, Cunha-Ferreira I, Cloin BM, van Battum EY, Will L, et al. (June 2014).
3573:
2418:
2054:
1995:
1860:
1803:
1390:. Bioinformatics analysis suggested CAMSAP2 is involved in epithelial-mesenchymal transition and the
1273:
caused by the injury, enabling proper distribution of BTB-associated proteins at the cell junctions.
131:
46:
2347:"CAMSAP2-mediated noncentrosomal microtubule acetylation drives hepatocellular carcinoma metastasis"
2254:"Microtubule minus-end binding protein CAMSAP2 controls axon specification and dendrite development"
4880:
3513:
2570:"The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins"
1603:"The CKK domain (DUF1781) binds microtubules and defines the CAMSAP/ssp4 family of animal proteins"
1553:"Role of microtubule +TIPs and -TIPs in spermatogenesis - Insights from studies of toxicant models"
1398:. In the mouse model, CAMSAP2 overexpressing xenografts illustrated enhanced metastasis, increased
1152:
954:
950:
925:
921:
895:
891:
887:
866:
858:
854:
2203:"CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation"
2152:"CAMSAP2 organizes a γ-tubulin-independent microtubule nucleation centre through phase separation"
3333:
2963:
91:
929:
862:
2568:
Baines AJ, Bignone PA, King MD, Maggs AM, Bennett PM, Pinder JC, et al. (September 2009).
2201:
Imasaki T, Kikkawa S, Niwa S, Saijo-Hamano Y, Shigematsu H, Aoyama K, et al. (June 2022).
2041:
Ho KH, Jayathilake A, Yagan M, Nour A, Osipovich AB, Magnuson MA, et al. (February 2023).
1730:
Varadi M, Anyango S, Deshpande M, Nair S, Natassia C, Yordanova G, et al. (January 2022).
1601:
Baines AJ, Bignone PA, King MD, Maggs AM, Bennett PM, Pinder JC, et al. (September 2009).
1195:
nucleation. CAMSAP2 achieves the increase by clustering with the αβ-tubulin dimers to generate
4731:
4434:
3095:
2591:
2545:
2496:
2444:
2376:
2327:
2275:
2234:
2183:
2132:
2080:
2023:
1964:
1894:
1876:
1829:
1761:
1672:
1622:
1572:
1246:
1148:
39:
4454:
1790:
Jumper J, Evans R, Pritzel A, Green T, Figurnov M, Ronneberger O, et al. (August 2021).
87:
4679:
4386:
4371:
4366:
4361:
4356:
4346:
4267:
3976:
3956:
3926:
3921:
3803:
3158:
3153:
2581:
2535:
2527:
2486:
2478:
2434:
2426:
2366:
2358:
2317:
2309:
2265:
2224:
2214:
2173:
2163:
2122:
2070:
2062:
2013:
2003:
1954:
1884:
1868:
1819:
1811:
1751:
1743:
1664:
1614:
1564:
336:
267:
211:
166:
4596:
4591:
4586:
4581:
4336:
4326:
4316:
4311:
4282:
3986:
3981:
3028:
2916:
2906:
2881:
2861:
2765:
2745:
4821:
3435:
3285:
3168:
2988:
1270:
1262:
1047:
311:
2482:
1199:
from which multiple microtubules can originate, promoting new astral microtubule growth.
2491:
2466:
2422:
2058:
1999:
1864:
1807:
1167:
4784:
4647:
3344:
3175:
2684:
2540:
2515:
2439:
2406:
2371:
2322:
2297:
2229:
2202:
2178:
2151:
2075:
2018:
1983:
1889:
1848:
1824:
1791:
1756:
1364:
1266:
1258:
1144:
1093:
1066:
2043:"CAMSAP2 localizes to the Golgi in islet β-cells and facilitates Golgi-ER trafficking"
1651:
Wu J, de Heus C, Liu Q, Bouchet BP, Noordstra I, Jiang K, et al. (October 2016).
654:
649:
644:
639:
634:
629:
624:
619:
614:
598:
593:
588:
583:
578:
573:
568:
563:
547:
542:
537:
532:
527:
4934:
4848:
4843:
3808:
3678:
3627:
3577:
3517:
3439:
3407:
3348:
3134:
2653:
1187:
514:
71:
4692:
3747:
3502:
3046:
2638:
1849:"Structural determinants of microtubule minus end preference in CAMSAP CKK domains"
1568:
1391:
1380:
1242:
1156:
329:
108:
4664:
4642:
2109:
Jiang K, Hua S, Mohan R, Grigoriev I, Yau KW, Liu Q, et al. (February 2014).
1941:
Jiang K, Hua S, Mohan R, Grigoriev I, Yau KW, Liu Q, et al. (February 2014).
1180:
2270:
2253:
2127:
2110:
1959:
1942:
1912:
1668:
1552:
95:
4838:
4789:
4659:
4549:
3879:
3323:
3278:
3197:
3119:
2667:
2111:"Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition"
1943:"Microtubule minus-end stabilization by polymerization-driven CAMSAP deposition"
1509:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1491:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1352:
1079:
1042:
2603:
2531:
2430:
2066:
1988:
Proceedings of the
National Academy of Sciences of the United States of America
1872:
1815:
1652:
412:
4890:
4809:
4799:
4687:
3798:
3777:
3543:
3480:
3475:
3470:
3450:
3425:
3413:
3399:
3394:
3389:
3384:
3379:
3374:
3369:
3364:
3359:
3221:
3103:
3092:
3078:
2694:
2516:"Cancer Cell Invasion: Treatment and Monitoring Opportunities in Nanomedicine"
1847:
Atherton J, Luo Y, Xiang S, Yang C, Rai A, Jiang K, et al. (2019-11-20).
1407:
1403:
1372:
1368:
1348:
1307:
1229:
1191:
1132:
1055:
228:
125:
75:
2042:
1880:
1224:
normally are not associated with any central microtubule-organizing centers (
50:, CAMSAP1L1, calmodulin regulated spectrin associated protein family member 2
4719:
4714:
4709:
4669:
4507:
4502:
4497:
3855:
3835:
3490:
3485:
3465:
3460:
3455:
3445:
3354:
3258:
3192:
2586:
2569:
2008:
1618:
1318:
CAMSAP2 promotes the migration of colorectal cancer cells by activating the
1128:
684:
472:
350:
295:
282:
194:
181:
83:
2595:
2549:
2500:
2448:
2380:
2331:
2296:
Mao BP, Li L, Ge R, Li C, Wong CK, Silvestrini B, et al. (June 2019).
2279:
2238:
2187:
2136:
2084:
2027:
1968:
1898:
1833:
1765:
1747:
1701:
1676:
1626:
1576:
2313:
1522:
1031:
Calmodulin-regulated spectrin-associated protein family member 2 (CAMSAP2)
1018:
1013:
4833:
4794:
4726:
4699:
4566:
4554:
4429:
4424:
3865:
3860:
3782:
3216:
3211:
3073:
2465:
Zuo L, Wang L, Yang Z, Li J, Wang W, Li J, et al. (September 2023).
1399:
1376:
1331:
1217:
1002:
829:
810:
2219:
2168:
4860:
4814:
4704:
4634:
4603:
4533:
4528:
4492:
4482:
4449:
4419:
4414:
4409:
4404:
4089:
4021:
4016:
4011:
4006:
4001:
3893:
3830:
3318:
3263:
3204:
3187:
3148:
2634:
2362:
2345:
Li D, Ding X, Xie M, Huang Z, Han P, Tian D, et al. (2020-02-19).
1731:
1424:
1419:
1115:
1083:
1034:
796:
751:
2471:
Nan Fang Yi Ke da Xue Xue Bao = Journal of
Southern Medical University
1653:"Molecular Pathway of Microtubule Organization at the Golgi Apparatus"
4779:
4761:
4756:
4751:
4746:
4736:
4571:
4464:
4459:
4444:
4439:
4351:
4297:
4262:
4237:
4232:
4227:
4222:
4212:
4207:
4197:
4182:
4177:
4059:
4054:
4049:
3961:
3951:
3931:
3916:
3911:
3906:
3901:
3767:
3538:
3533:
3290:
2956:
2951:
2941:
2719:
1387:
1221:
1059:
986:
706:
2346:
4804:
4576:
4559:
4396:
4391:
4381:
4376:
4341:
4331:
4321:
4306:
4287:
4277:
4272:
4257:
4252:
4247:
4242:
4217:
4202:
4192:
4187:
4172:
4167:
4147:
4142:
4137:
4132:
4127:
4122:
4117:
4112:
4107:
4102:
4097:
4069:
4064:
4031:
4026:
3996:
3991:
3971:
3966:
3946:
3936:
3851:
3729:
3724:
3719:
3714:
3709:
3704:
3699:
3694:
3689:
3684:
3668:
3663:
3658:
3653:
3648:
3643:
3638:
3633:
3608:
3603:
3598:
3593:
3588:
3583:
3563:
3558:
3553:
3548:
3528:
3523:
3233:
3163:
3112:
3109:
3106:
3098:
3087:
3084:
3081:
3066:
3061:
3056:
3051:
3023:
3013:
2998:
2931:
2921:
2901:
2876:
2871:
2856:
2846:
2841:
2836:
2831:
2826:
2821:
2806:
2760:
2755:
2750:
2740:
2735:
2730:
2709:
2704:
2699:
2689:
2676:
1335:
1327:
1295:
1291:
1166:
1065:
1051:
1359:, where epithelial cells acquire the invasive characteristics of
669:
665:
4905:
4900:
4895:
4855:
4826:
4741:
4618:
4613:
4608:
4512:
4162:
4157:
4152:
4079:
4074:
3941:
3823:
3818:
3813:
3273:
3268:
3226:
3139:
3129:
3124:
3018:
3008:
3003:
2993:
2983:
2978:
2973:
2968:
2891:
2816:
2811:
2801:
2796:
2791:
2786:
2781:
2776:
1299:
1225:
1213:
1143:
CAMSAP2-dependent microtubule organization promotes directional
1038:
63:
2607:
1096:. In addition to a CKK domain, CAMSAP2 contains an N-terminal
2514:
Veiseh O, Kievit FM, Ellenbogen RG, Zhang M (February 2011).
1792:"Highly accurate protein structure prediction with AlphaFold"
1241:
CAMSAP2 is involved in targeting microtubule minus-ends in
1175:
The initial polymerization of microtubules can be called "
319:
1982:
Tanaka N, Meng W, Nagae S, Takeichi M (December 2012).
1265:
and BTB dynamics. In a model of
Sertoli cell injury, a
1351:. One hundred six cancer patients underwent a radical
1046:
stabilizes and attaches microtubule minus ends to the
484:
4873:
4772:
4678:
4633:
4542:
4521:
4473:
4296:
4088:
4040:
3892:
3878:
3844:
3791:
3760:
3740:
3619:
3501:
3332:
3314:
3303:
3246:
3039:
2718:
2675:
2666:
2652:
2645:
943:
914:
880:
847:
650:
negative regulation of microtubule depolymerization
1465:
1463:
1461:
1444:
1442:
1440:
1298:transrepression of HDAC6 along the Trio-dependent
266:
165:
1179:". The process occurs spontaneously via soluble
2405:Wang X, Liu Y, Ding Y, Feng G (October 2022).
1470:GRCm38: Ensembl release 89: ENSMUSG00000041570
1208:Regulator of neuronal polarity and development
2619:
8:
1190:ring complex is recruited to facilitate the
1449:GRCh38: Ensembl release 89: ENSG00000118200
3889:
3329:
3311:
2672:
2663:
2649:
2626:
2612:
2604:
680:
510:
307:
206:
103:
2585:
2539:
2490:
2438:
2370:
2321:
2269:
2228:
2218:
2177:
2167:
2126:
2074:
2017:
2007:
1958:
1888:
1823:
1755:
1306:pathway, inhibiting CAMSAP2-mediated HCC
1159:and facilitate effective cell migration.
1037:in humans that is encoded by the CAMSAP2
630:regulation of microtubule polymerization
1551:Mao BP, Ge R, Cheng CY (January 2020).
1436:
1237:Regulator of blood–testis barrier (BTB)
1212:CAMSAP2 is responsible for controlling
1109:Non-centrosomal microtubule maintenance
1702:"AlphaFold Protein Structure Database"
20:
2460:
2458:
2291:
2289:
1294:promoter region. CAMSAP2 activates a
625:microtubule cytoskeleton organization
271:
232:
227:
170:
129:
124:
7:
2483:10.12122/j.issn.1673-4254.2023.09.02
1070:3D rendering of the CAMSAP2 protein.
655:cytoplasmic microtubule organization
615:regulation of organelle organization
447:vestibular membrane of cochlear duct
940:
911:
877:
844:
820:
801:
775:
756:
730:
711:
635:regulation of dendrite development
489:
407:
345:
324:
14:
1357:epithelial-mesenchymal transition
361:lateral nuclear group of thalamus
3254:Wiskott–Aldrich syndrome protein
1330:signaling pathway. Acting as an
645:regulation of Golgi organization
255:
248:
242:
219:
154:
147:
141:
116:
4475:Microtubule organising proteins
2574:Molecular Biology and Evolution
2387:from the original on 2024-03-11
2091:from the original on 2024-04-15
1923:from the original on 2024-04-15
1772:from the original on 2024-04-15
1712:from the original on 2022-10-01
1683:from the original on 2024-04-15
1633:from the original on 2022-06-15
1607:Molecular Biology and Evolution
1583:from the original on 2024-04-15
1533:from the original on 2024-02-27
2520:Advanced Drug Delivery Reviews
1569:10.1016/j.reprotox.2019.11.006
1288:hepatocellular carcinoma (HCC)
1282:Hepatocellular carcinoma (HCC)
473:More reference expression data
455:Region I of hippocampus proper
397:Region I of hippocampus proper
1:
4522:Microtubule severing proteins
1292:histone deacetylase 6 (HDAC6)
1100:involved with actin binding.
620:neuron projection development
538:microtubule minus-end binding
240:
139:
3182:actin depolymerizing factors
2271:10.1016/j.neuron.2014.04.019
2128:10.1016/j.devcel.2014.01.001
1960:10.1016/j.devcel.2014.01.001
1669:10.1016/j.devcel.2016.08.009
4941:Genes on human chromosome 1
4660:Plakoglobin (gamma catenin)
1220:development. In the brain,
4962:
2532:10.1016/j.addr.2011.01.010
2431:10.1038/s41598-022-21345-7
2067:10.1016/j.isci.2023.105938
1873:10.1038/s41467-019-13247-6
1816:10.1038/s41586-021-03819-2
431:superior cervical ganglion
4916:
1505:"Mouse PubMed Reference:"
1487:"Human PubMed Reference:"
1363:. Researchers utilized a
1017:
1012:
1008:
1001:
985:
972:Chr 1: 200.74 – 200.86 Mb
966:
947:
918:
907:
884:
851:
840:
827:
823:
808:
804:
795:
782:
778:
763:
759:
750:
737:
733:
718:
714:
705:
690:
683:
679:
663:
513:
509:
497:
492:
483:
470:
419:
410:
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
4886:Prokaryotic cytoskeleton
1384:carcinoembryonic antigen
1098:calponin homology domain
979:Chr 1: 136.2 – 136.27 Mb
2009:10.1073/pnas.1218017109
1557:Reproductive Toxicology
1251:seminiferous epithelium
16:Protein found in humans
1736:Nucleic Acids Research
1177:microtubule nucleation
1172:
1163:Microtubule nucleation
1123:Pancreatic islet cells
1071:
381:superior frontal gyrus
3506:(hard alpha-keratins)
3337:(soft alpha-keratins)
2587:10.1093/molbev/msp115
2314:10.1210/en.2018-01097
1853:Nature Communications
1619:10.1093/molbev/msp115
1170:
1069:
594:microtubule minus-end
377:middle temporal gyrus
4921:cytoskeletal defects
4881:Major sperm proteins
1748:10.1093/nar/gkab1061
1527:www.ncbi.nlm.nih.gov
1371:gastric cancer cell
1255:blood-testis barrier
1153:wound healing assays
234:Chromosome 1 (mouse)
132:Chromosome 1 (human)
3334:Epithelial keratins
2423:2022NatSR..1216899W
2220:10.7554/eLife.77365
2169:10.7554/eLife.77365
2059:2023iSci...26j5938H
2000:2012PNAS..10920029T
1994:(49): 20029–20034.
1865:2019NatCo..10.5236A
1808:2021Natur.596..583J
1706:alphafold.ebi.ac.uk
528:microtubule binding
435:trigeminal ganglion
96:CAMSAP2 - orthologs
2411:Scientific Reports
2363:10.7150/thno.42596
2115:Developmental Cell
1947:Developmental Cell
1657:Developmental Cell
1216:specification and
1173:
1072:
785:ENSMUSG00000041570
608:Biological process
557:Cellular component
533:calmodulin binding
521:Molecular function
4928:
4927:
4869:
4868:
4629:
4628:
3874:
3873:
3756:
3755:
3299:
3298:
3242:
3241:
1802:(7873): 583–589.
1742:(D1): D439–D444.
1361:mesenchymal cells
1314:Colorectal cancer
1277:Clinical research
1247:basement membrane
1149:cell polarization
1082:are cytoskeletal
1028:
1027:
1024:
1023:
997:
996:
962:
961:
937:
936:
903:
902:
874:
873:
836:
835:
817:
816:
791:
790:
772:
771:
746:
745:
727:
726:
675:
674:
505:
504:
501:
500:
479:
478:
466:
465:
404:
403:
385:entorhinal cortex
365:postcentral gyrus
302:
301:
201:
200:
4953:
3890:
3330:
3312:
2673:
2664:
2650:
2628:
2621:
2614:
2605:
2599:
2589:
2580:(9): 2005–2014.
2554:
2553:
2543:
2511:
2505:
2504:
2494:
2477:(9): 1460–1468.
2462:
2453:
2452:
2442:
2402:
2396:
2395:
2393:
2392:
2374:
2357:(8): 3749–3766.
2342:
2336:
2335:
2325:
2308:(6): 1448–1467.
2293:
2284:
2283:
2273:
2264:(5): 1058–1073.
2249:
2243:
2242:
2232:
2222:
2198:
2192:
2191:
2181:
2171:
2147:
2141:
2140:
2130:
2106:
2100:
2099:
2097:
2096:
2078:
2038:
2032:
2031:
2021:
2011:
1979:
1973:
1972:
1962:
1938:
1932:
1931:
1929:
1928:
1909:
1903:
1902:
1892:
1844:
1838:
1837:
1827:
1787:
1781:
1780:
1778:
1777:
1759:
1727:
1721:
1720:
1718:
1717:
1698:
1692:
1691:
1689:
1688:
1648:
1642:
1641:
1639:
1638:
1613:(9): 2005–2014.
1598:
1592:
1591:
1589:
1588:
1548:
1542:
1541:
1539:
1538:
1519:
1513:
1512:
1501:
1495:
1494:
1483:
1477:
1467:
1456:
1446:
1406:, and decreased
1365:nude mouse model
1010:
1009:
981:
974:
957:
941:
932:
912:
908:RefSeq (protein)
898:
878:
869:
845:
821:
802:
776:
757:
731:
712:
681:
640:axon development
543:spectrin binding
511:
490:
475:
451:secondary oocyte
443:substantia nigra
415:
413:Top expressed in
408:
393:Brodmann area 46
389:Brodmann area 23
373:endothelial cell
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
49:
42:
21:
4961:
4960:
4956:
4955:
4954:
4952:
4951:
4950:
4931:
4930:
4929:
4924:
4912:
4865:
4768:
4674:
4625:
4538:
4517:
4469:
4292:
4084:
4036:
3882:
3870:
3840:
3787:
3752:
3736:
3620:Ungrouped alpha
3615:
3505:
3497:
3336:
3322:
3316:
3306:
3295:
3238:
3035:
2714:
2656:
2641:
2632:
2602:
2567:
2563:
2561:Further reading
2558:
2557:
2513:
2512:
2508:
2464:
2463:
2456:
2404:
2403:
2399:
2390:
2388:
2344:
2343:
2339:
2295:
2294:
2287:
2251:
2250:
2246:
2200:
2199:
2195:
2149:
2148:
2144:
2108:
2107:
2103:
2094:
2092:
2040:
2039:
2035:
1981:
1980:
1976:
1940:
1939:
1935:
1926:
1924:
1917:www.uniprot.org
1911:
1910:
1906:
1846:
1845:
1841:
1789:
1788:
1784:
1775:
1773:
1729:
1728:
1724:
1715:
1713:
1700:
1699:
1695:
1686:
1684:
1650:
1649:
1645:
1636:
1634:
1600:
1599:
1595:
1586:
1584:
1550:
1549:
1545:
1536:
1534:
1521:
1520:
1516:
1503:
1502:
1498:
1485:
1484:
1480:
1468:
1459:
1447:
1438:
1433:
1416:
1396:TGF-β signaling
1344:
1316:
1284:
1279:
1271:actin filaments
1263:spermatogenesis
1239:
1210:
1205:
1165:
1141:
1125:
1111:
1106:
1077:
1019:View/Edit Mouse
1014:View/Edit Human
977:
970:
967:Location (UCSC)
953:
949:
928:
924:
920:
894:
890:
886:
865:
861:
857:
853:
766:ENSG00000118200
659:
603:
599:Golgi apparatus
589:microtubule end
552:
548:protein binding
471:
462:
457:
453:
449:
445:
441:
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
4959:
4957:
4949:
4948:
4946:Human proteins
4943:
4933:
4932:
4926:
4925:
4917:
4914:
4913:
4911:
4910:
4909:
4908:
4903:
4898:
4893:
4883:
4877:
4875:
4871:
4870:
4867:
4866:
4864:
4863:
4858:
4853:
4852:
4851:
4846:
4836:
4831:
4830:
4829:
4819:
4818:
4817:
4812:
4807:
4802:
4797:
4792:
4787:
4785:Corneodesmosin
4776:
4774:
4770:
4769:
4767:
4766:
4765:
4764:
4759:
4754:
4749:
4744:
4739:
4734:
4724:
4723:
4722:
4717:
4712:
4702:
4697:
4696:
4695:
4684:
4682:
4676:
4675:
4673:
4672:
4667:
4662:
4657:
4656:
4655:
4645:
4639:
4637:
4631:
4630:
4627:
4626:
4624:
4623:
4622:
4621:
4616:
4611:
4601:
4600:
4599:
4594:
4589:
4584:
4579:
4569:
4564:
4563:
4562:
4552:
4546:
4544:
4540:
4539:
4537:
4536:
4531:
4525:
4523:
4519:
4518:
4516:
4515:
4510:
4505:
4500:
4495:
4490:
4485:
4479:
4477:
4471:
4470:
4468:
4467:
4462:
4457:
4452:
4447:
4442:
4437:
4432:
4427:
4422:
4417:
4412:
4407:
4400:
4399:
4394:
4389:
4384:
4379:
4374:
4369:
4364:
4359:
4354:
4349:
4344:
4339:
4334:
4329:
4324:
4319:
4314:
4309:
4302:
4300:
4294:
4293:
4291:
4290:
4285:
4280:
4275:
4270:
4265:
4260:
4255:
4250:
4245:
4240:
4235:
4230:
4225:
4220:
4215:
4210:
4205:
4200:
4195:
4190:
4185:
4180:
4175:
4170:
4165:
4160:
4155:
4150:
4145:
4140:
4135:
4130:
4125:
4120:
4115:
4110:
4105:
4100:
4094:
4092:
4086:
4085:
4083:
4082:
4077:
4072:
4067:
4062:
4057:
4052:
4046:
4044:
4038:
4037:
4035:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3898:
3896:
3887:
3876:
3875:
3872:
3871:
3869:
3868:
3863:
3858:
3852:Nuclear lamins
3848:
3846:
3842:
3841:
3839:
3838:
3833:
3828:
3827:
3826:
3821:
3816:
3806:
3801:
3795:
3793:
3789:
3788:
3786:
3785:
3780:
3775:
3770:
3764:
3762:
3758:
3757:
3754:
3753:
3751:
3750:
3744:
3742:
3738:
3737:
3735:
3734:
3733:
3732:
3727:
3722:
3717:
3712:
3707:
3702:
3697:
3692:
3687:
3674:
3673:
3672:
3671:
3666:
3661:
3656:
3651:
3646:
3641:
3636:
3623:
3621:
3617:
3616:
3614:
3613:
3612:
3611:
3606:
3601:
3596:
3591:
3586:
3569:
3568:
3567:
3566:
3561:
3556:
3551:
3546:
3541:
3536:
3531:
3526:
3509:
3507:
3499:
3498:
3496:
3495:
3494:
3493:
3488:
3483:
3478:
3473:
3468:
3463:
3458:
3453:
3448:
3431:
3430:
3429:
3428:
3418:
3417:
3416:
3404:
3403:
3402:
3397:
3392:
3387:
3382:
3377:
3372:
3367:
3362:
3357:
3340:
3338:
3327:
3309:
3301:
3300:
3297:
3296:
3294:
3293:
3288:
3283:
3282:
3281:
3276:
3271:
3261:
3256:
3250:
3248:
3244:
3243:
3240:
3239:
3237:
3236:
3231:
3230:
3229:
3224:
3214:
3209:
3208:
3207:
3202:
3201:
3200:
3195:
3178:
3176:Arp2/3 complex
3173:
3172:
3171:
3166:
3161:
3156:
3145:
3144:
3143:
3142:
3137:
3132:
3127:
3117:
3116:
3115:
3101:
3090:
3071:
3070:
3069:
3064:
3059:
3054:
3043:
3041:
3037:
3036:
3034:
3033:
3032:
3031:
3026:
3021:
3016:
3011:
3006:
3001:
2996:
2991:
2986:
2981:
2976:
2971:
2961:
2960:
2959:
2954:
2946:
2945:
2944:
2936:
2935:
2934:
2926:
2925:
2924:
2919:
2911:
2910:
2909:
2904:
2896:
2895:
2894:
2886:
2885:
2884:
2879:
2874:
2866:
2865:
2864:
2859:
2851:
2850:
2849:
2844:
2839:
2834:
2829:
2824:
2819:
2814:
2809:
2804:
2799:
2794:
2789:
2784:
2779:
2771:
2770:
2769:
2763:
2758:
2753:
2748:
2743:
2738:
2733:
2724:
2722:
2716:
2715:
2713:
2712:
2707:
2702:
2697:
2692:
2687:
2681:
2679:
2670:
2661:
2654:Microfilaments
2647:
2643:
2642:
2633:
2631:
2630:
2623:
2616:
2608:
2601:
2600:
2564:
2562:
2559:
2556:
2555:
2526:(8): 582–596.
2506:
2473:(in Chinese).
2454:
2397:
2337:
2285:
2244:
2193:
2142:
2121:(3): 295–309.
2101:
2033:
1974:
1953:(3): 295–309.
1933:
1904:
1839:
1782:
1722:
1693:
1643:
1593:
1543:
1514:
1496:
1478:
1457:
1435:
1434:
1432:
1429:
1428:
1427:
1422:
1415:
1412:
1375:to verify the
1343:
1342:Gastric cancer
1340:
1315:
1312:
1283:
1280:
1278:
1275:
1259:tight junction
1238:
1235:
1209:
1206:
1204:
1201:
1164:
1161:
1145:cell migration
1140:
1137:
1127:In pancreatic
1124:
1121:
1110:
1107:
1105:
1102:
1094:polymerization
1076:
1073:
1026:
1025:
1022:
1021:
1016:
1006:
1005:
999:
998:
995:
994:
992:
990:
983:
982:
975:
968:
964:
963:
960:
959:
945:
944:
938:
935:
934:
916:
915:
909:
905:
904:
901:
900:
882:
881:
875:
872:
871:
849:
848:
842:
838:
837:
834:
833:
825:
824:
818:
815:
814:
806:
805:
799:
793:
792:
789:
788:
780:
779:
773:
770:
769:
761:
760:
754:
748:
747:
744:
743:
735:
734:
728:
725:
724:
716:
715:
709:
703:
702:
697:
692:
688:
687:
677:
676:
673:
672:
661:
660:
658:
657:
652:
647:
642:
637:
632:
627:
622:
617:
611:
609:
605:
604:
602:
601:
596:
591:
586:
581:
576:
571:
566:
560:
558:
554:
553:
551:
550:
545:
540:
535:
530:
524:
522:
518:
517:
507:
506:
503:
502:
499:
498:
495:
494:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
4958:
4947:
4944:
4942:
4939:
4938:
4936:
4923:
4922:
4915:
4907:
4904:
4902:
4899:
4897:
4894:
4892:
4889:
4888:
4887:
4884:
4882:
4879:
4878:
4876:
4872:
4862:
4859:
4857:
4854:
4850:
4847:
4845:
4842:
4841:
4840:
4837:
4835:
4832:
4828:
4825:
4824:
4823:
4820:
4816:
4813:
4811:
4808:
4806:
4803:
4801:
4798:
4796:
4793:
4791:
4788:
4786:
4783:
4782:
4781:
4778:
4777:
4775:
4771:
4763:
4760:
4758:
4755:
4753:
4750:
4748:
4745:
4743:
4740:
4738:
4735:
4733:
4730:
4729:
4728:
4725:
4721:
4718:
4716:
4713:
4711:
4708:
4707:
4706:
4703:
4701:
4698:
4694:
4691:
4690:
4689:
4686:
4685:
4683:
4681:
4677:
4671:
4668:
4666:
4665:Delta catenin
4663:
4661:
4658:
4654:
4651:
4650:
4649:
4646:
4644:
4643:Alpha catenin
4641:
4640:
4638:
4636:
4632:
4620:
4617:
4615:
4612:
4610:
4607:
4606:
4605:
4602:
4598:
4595:
4593:
4590:
4588:
4585:
4583:
4580:
4578:
4575:
4574:
4573:
4570:
4568:
4565:
4561:
4558:
4557:
4556:
4553:
4551:
4548:
4547:
4545:
4541:
4535:
4532:
4530:
4527:
4526:
4524:
4520:
4514:
4511:
4509:
4506:
4504:
4501:
4499:
4496:
4494:
4491:
4489:
4486:
4484:
4481:
4480:
4478:
4476:
4472:
4466:
4463:
4461:
4458:
4456:
4453:
4451:
4448:
4446:
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4426:
4423:
4421:
4418:
4416:
4413:
4411:
4408:
4406:
4403:cytoplasmic:
4402:
4401:
4398:
4395:
4393:
4390:
4388:
4385:
4383:
4380:
4378:
4375:
4373:
4370:
4368:
4365:
4363:
4360:
4358:
4355:
4353:
4350:
4348:
4345:
4343:
4340:
4338:
4335:
4333:
4330:
4328:
4325:
4323:
4320:
4318:
4315:
4313:
4310:
4308:
4304:
4303:
4301:
4299:
4295:
4289:
4286:
4284:
4281:
4279:
4276:
4274:
4271:
4269:
4266:
4264:
4261:
4259:
4256:
4254:
4251:
4249:
4246:
4244:
4241:
4239:
4236:
4234:
4231:
4229:
4226:
4224:
4221:
4219:
4216:
4214:
4211:
4209:
4206:
4204:
4201:
4199:
4196:
4194:
4191:
4189:
4186:
4184:
4181:
4179:
4176:
4174:
4171:
4169:
4166:
4164:
4161:
4159:
4156:
4154:
4151:
4149:
4146:
4144:
4141:
4139:
4136:
4134:
4131:
4129:
4126:
4124:
4121:
4119:
4116:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4095:
4093:
4091:
4087:
4081:
4078:
4076:
4073:
4071:
4068:
4066:
4063:
4061:
4058:
4056:
4053:
4051:
4048:
4047:
4045:
4043:
4039:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3899:
3897:
3895:
3891:
3888:
3886:
3881:
3877:
3867:
3864:
3862:
3859:
3857:
3853:
3850:
3849:
3847:
3843:
3837:
3834:
3832:
3829:
3825:
3822:
3820:
3817:
3815:
3812:
3811:
3810:
3809:Neurofilament
3807:
3805:
3802:
3800:
3797:
3796:
3794:
3790:
3784:
3781:
3779:
3776:
3774:
3771:
3769:
3766:
3765:
3763:
3759:
3749:
3746:
3745:
3743:
3739:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3711:
3708:
3706:
3703:
3701:
3698:
3696:
3693:
3691:
3688:
3686:
3683:
3682:
3681:
3680:
3679:chromosome 12
3676:
3675:
3670:
3667:
3665:
3662:
3660:
3657:
3655:
3652:
3650:
3647:
3645:
3642:
3640:
3637:
3635:
3632:
3631:
3630:
3629:
3628:chromosome 17
3625:
3624:
3622:
3618:
3610:
3607:
3605:
3602:
3600:
3597:
3595:
3592:
3590:
3587:
3585:
3582:
3581:
3580:
3579:
3578:chromosome 12
3575:
3571:
3570:
3565:
3562:
3560:
3557:
3555:
3552:
3550:
3547:
3545:
3542:
3540:
3537:
3535:
3532:
3530:
3527:
3525:
3522:
3521:
3520:
3519:
3518:chromosome 17
3515:
3511:
3510:
3508:
3504:
3503:Hair keratins
3500:
3492:
3489:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3454:
3452:
3449:
3447:
3444:
3443:
3442:
3441:
3440:chromosome 12
3437:
3433:
3432:
3427:
3424:
3423:
3422:
3419:
3415:
3412:
3411:
3410:
3409:
3408:chromosome 12
3405:
3401:
3398:
3396:
3393:
3391:
3388:
3386:
3383:
3381:
3378:
3376:
3373:
3371:
3368:
3366:
3363:
3361:
3358:
3356:
3353:
3352:
3351:
3350:
3349:chromosome 17
3346:
3342:
3341:
3339:
3335:
3331:
3328:
3325:
3320:
3313:
3310:
3308:
3305:Intermediate
3302:
3292:
3289:
3287:
3284:
3280:
3277:
3275:
3272:
3270:
3267:
3266:
3265:
3262:
3260:
3257:
3255:
3252:
3251:
3249:
3245:
3235:
3232:
3228:
3225:
3223:
3220:
3219:
3218:
3215:
3213:
3210:
3206:
3203:
3199:
3196:
3194:
3191:
3190:
3189:
3186:
3185:
3184:
3183:
3179:
3177:
3174:
3170:
3167:
3165:
3162:
3160:
3157:
3155:
3152:
3151:
3150:
3147:
3146:
3141:
3138:
3136:
3133:
3131:
3128:
3126:
3123:
3122:
3121:
3118:
3114:
3111:
3108:
3105:
3102:
3100:
3097:
3094:
3091:
3089:
3086:
3083:
3080:
3077:
3076:
3075:
3072:
3068:
3065:
3063:
3060:
3058:
3055:
3053:
3050:
3049:
3048:
3045:
3044:
3042:
3038:
3030:
3027:
3025:
3022:
3020:
3017:
3015:
3012:
3010:
3007:
3005:
3002:
3000:
2997:
2995:
2992:
2990:
2987:
2985:
2982:
2980:
2977:
2975:
2972:
2970:
2967:
2966:
2965:
2962:
2958:
2955:
2953:
2950:
2949:
2947:
2943:
2940:
2939:
2937:
2933:
2930:
2929:
2927:
2923:
2920:
2918:
2915:
2914:
2912:
2908:
2905:
2903:
2900:
2899:
2897:
2893:
2890:
2889:
2887:
2883:
2880:
2878:
2875:
2873:
2870:
2869:
2867:
2863:
2860:
2858:
2855:
2854:
2852:
2848:
2845:
2843:
2840:
2838:
2835:
2833:
2830:
2828:
2825:
2823:
2820:
2818:
2815:
2813:
2810:
2808:
2805:
2803:
2800:
2798:
2795:
2793:
2790:
2788:
2785:
2783:
2780:
2778:
2775:
2774:
2772:
2767:
2764:
2762:
2759:
2757:
2754:
2752:
2749:
2747:
2744:
2742:
2739:
2737:
2734:
2732:
2729:
2728:
2726:
2725:
2723:
2721:
2717:
2711:
2708:
2706:
2703:
2701:
2698:
2696:
2693:
2691:
2688:
2686:
2683:
2682:
2680:
2678:
2674:
2671:
2669:
2665:
2662:
2660:
2655:
2651:
2648:
2644:
2640:
2636:
2629:
2624:
2622:
2617:
2615:
2610:
2609:
2606:
2597:
2593:
2588:
2583:
2579:
2575:
2571:
2566:
2565:
2560:
2551:
2547:
2542:
2537:
2533:
2529:
2525:
2521:
2517:
2510:
2507:
2502:
2498:
2493:
2488:
2484:
2480:
2476:
2472:
2468:
2461:
2459:
2455:
2450:
2446:
2441:
2436:
2432:
2428:
2424:
2420:
2416:
2412:
2408:
2401:
2398:
2386:
2382:
2378:
2373:
2368:
2364:
2360:
2356:
2352:
2348:
2341:
2338:
2333:
2329:
2324:
2319:
2315:
2311:
2307:
2303:
2302:Endocrinology
2299:
2292:
2290:
2286:
2281:
2277:
2272:
2267:
2263:
2259:
2255:
2248:
2245:
2240:
2236:
2231:
2226:
2221:
2216:
2212:
2208:
2204:
2197:
2194:
2189:
2185:
2180:
2175:
2170:
2165:
2161:
2157:
2153:
2146:
2143:
2138:
2134:
2129:
2124:
2120:
2116:
2112:
2105:
2102:
2090:
2086:
2082:
2077:
2072:
2068:
2064:
2060:
2056:
2053:(2): 105938.
2052:
2048:
2044:
2037:
2034:
2029:
2025:
2020:
2015:
2010:
2005:
2001:
1997:
1993:
1989:
1985:
1978:
1975:
1970:
1966:
1961:
1956:
1952:
1948:
1944:
1937:
1934:
1922:
1918:
1914:
1908:
1905:
1900:
1896:
1891:
1886:
1882:
1878:
1874:
1870:
1866:
1862:
1858:
1854:
1850:
1843:
1840:
1835:
1831:
1826:
1821:
1817:
1813:
1809:
1805:
1801:
1797:
1793:
1786:
1783:
1771:
1767:
1763:
1758:
1753:
1749:
1745:
1741:
1737:
1733:
1726:
1723:
1711:
1707:
1703:
1697:
1694:
1682:
1678:
1674:
1670:
1666:
1662:
1658:
1654:
1647:
1644:
1632:
1628:
1624:
1620:
1616:
1612:
1608:
1604:
1597:
1594:
1582:
1578:
1574:
1570:
1566:
1562:
1558:
1554:
1547:
1544:
1532:
1528:
1524:
1518:
1515:
1510:
1506:
1500:
1497:
1492:
1488:
1482:
1479:
1475:
1471:
1466:
1464:
1462:
1458:
1454:
1450:
1445:
1443:
1441:
1437:
1430:
1426:
1423:
1421:
1418:
1417:
1413:
1411:
1409:
1405:
1401:
1397:
1393:
1389:
1385:
1382:
1381:tumor markers
1378:
1374:
1370:
1366:
1362:
1358:
1354:
1350:
1341:
1339:
1337:
1333:
1329:
1325:
1321:
1313:
1311:
1309:
1305:
1301:
1297:
1293:
1289:
1281:
1276:
1274:
1272:
1268:
1264:
1260:
1256:
1252:
1248:
1244:
1236:
1234:
1231:
1227:
1223:
1219:
1215:
1207:
1202:
1200:
1198:
1197:intermediates
1193:
1189:
1185:
1182:
1178:
1169:
1162:
1160:
1158:
1154:
1150:
1146:
1138:
1136:
1134:
1130:
1122:
1120:
1117:
1108:
1103:
1101:
1099:
1095:
1090:
1085:
1081:
1074:
1068:
1064:
1061:
1057:
1053:
1049:
1044:
1040:
1036:
1032:
1020:
1015:
1011:
1007:
1004:
1000:
993:
991:
988:
984:
980:
976:
973:
969:
965:
958:
956:
952:
946:
942:
939:
933:
931:
927:
923:
917:
913:
910:
906:
899:
897:
893:
889:
883:
879:
876:
870:
868:
864:
860:
856:
850:
846:
843:
841:RefSeq (mRNA)
839:
832:
831:
826:
822:
819:
813:
812:
807:
803:
800:
798:
794:
787:
786:
781:
777:
774:
768:
767:
762:
758:
755:
753:
749:
742:
741:
736:
732:
729:
723:
722:
717:
713:
710:
708:
704:
701:
698:
696:
693:
689:
686:
682:
678:
671:
667:
662:
656:
653:
651:
648:
646:
643:
641:
638:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
612:
610:
607:
606:
600:
597:
595:
592:
590:
587:
585:
582:
580:
577:
575:
572:
570:
567:
565:
562:
561:
559:
556:
555:
549:
546:
544:
541:
539:
536:
534:
531:
529:
526:
525:
523:
520:
519:
516:
515:Gene ontology
512:
508:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
426:
423:otolith organ
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
4918:
4693:Dystroglycan
4648:Beta catenin
4487:
3880:Microtubules
3748:Beta-keratin
3677:
3626:
3572:
3512:
3434:
3420:
3406:
3343:
3180:
3047:Tropomodulin
2639:cytoskeleton
2577:
2573:
2523:
2519:
2509:
2474:
2470:
2417:(1): 16899.
2414:
2410:
2400:
2389:. Retrieved
2354:
2351:Theranostics
2350:
2340:
2305:
2301:
2261:
2257:
2247:
2210:
2206:
2196:
2159:
2155:
2145:
2118:
2114:
2104:
2093:. Retrieved
2050:
2046:
2036:
1991:
1987:
1977:
1950:
1946:
1936:
1925:. Retrieved
1916:
1907:
1856:
1852:
1842:
1799:
1795:
1785:
1774:. Retrieved
1739:
1735:
1725:
1714:. Retrieved
1705:
1696:
1685:. Retrieved
1663:(1): 44–60.
1660:
1656:
1646:
1635:. Retrieved
1610:
1606:
1596:
1585:. Retrieved
1560:
1556:
1546:
1535:. Retrieved
1526:
1517:
1508:
1499:
1490:
1481:
1392:upregulation
1345:
1317:
1285:
1243:Sertoli cell
1240:
1211:
1174:
1157:cytoskeleton
1142:
1126:
1112:
1080:Microtubules
1078:
1054:complex and
1050:through the
1030:
1029:
955:NP_001334039
951:NP_001334038
948:
926:NP_001284637
922:NP_001284636
919:
896:NM_001347110
892:NM_001347109
888:NM_001081360
885:
867:NM_001389638
859:NM_001297708
855:NM_001297707
852:
828:
809:
783:
764:
738:
719:
699:
694:
579:cytoskeleton
335:
328:
294:136,273,842
281:136,195,861
193:200,860,704
180:200,738,893
55:External IDs
18:
4839:Plakophilin
4790:Desmoplakin
4550:Tau protein
3324:Cytokeratin
3120:Tropomyosin
2668:Myofilament
1859:(1): 5236.
1353:gastrectomy
1043:coiled-coil
574:microtubule
369:optic nerve
273:1|1 E4
33:Identifiers
4935:Categories
4919:See also:
4891:Crescentin
4810:Periplakin
4800:Envoplakin
4688:Dystrophin
4305:axonemal:
3799:Internexin
3778:Peripherin
2391:2024-04-15
2162:: e77365.
2095:2024-04-15
1927:2024-04-14
1776:2024-04-15
1716:2024-04-12
1687:2024-04-15
1637:2022-09-29
1587:2024-04-15
1537:2024-03-11
1476:, May 2017
1455:, May 2017
1431:References
1408:E-cadherin
1404:N-cadherin
1373:xenografts
1369:orthotopic
1349:metastasis
1308:metastasis
1230:centrosome
1203:Regulation
1192:nucleation
1181:αβ-tubulin
1089:CKK domain
1056:myomegalin
569:centrosome
339:(ortholog)
76:HomoloGene
4508:Centrin 3
4503:Centrin 2
4498:Centrin 1
3836:Syncoilin
3741:Not alpha
3307:filaments
3259:Fibrillin
1913:"UniProt"
1881:2041-1723
1563:: 43–52.
1267:knockdown
1188:γ-tubulin
1139:Migration
1075:Structure
930:NP_982284
863:NM_203459
685:Orthologs
564:cytoplasm
84:GeneCards
4874:Nonhuman
4834:Vinculin
4795:Dystonin
4727:Spectrin
4700:Utrophin
4680:Membrane
4635:Catenins
4567:Stathmin
4555:Dynactin
4435:DYNC2LI1
4430:DYNC1LI2
4425:DYNC1LI1
4090:Kinesins
3894:Tubulins
3783:Vimentin
3315:Type 1/2
3217:Profilin
3212:Gelsolin
3074:Troponin
2635:Proteins
2596:19508979
2550:21295093
2501:37814859
2492:10563100
2449:36207462
2385:Archived
2381:32206120
2332:30994903
2280:24908486
2239:35762204
2188:35762204
2137:24486153
2089:Archived
2085:36718359
2047:iScience
2028:23169647
1969:24486153
1921:Archived
1899:31748546
1834:34265844
1770:Archived
1766:34791371
1710:Archived
1681:Archived
1677:27666745
1631:Archived
1627:19508979
1581:Archived
1577:31756440
1531:Archived
1472:–
1451:–
1414:See also
1400:vimentin
1377:in vitro
1332:oncogene
1218:dendrite
1104:Function
1084:polymers
1003:Wikidata
664:Sources:
4861:PLEKHA7
4815:Plectin
4780:Plakins
4705:Ankyrin
4604:Dynamin
4534:Spastin
4529:Katanin
4493:CAMSAP3
4488:CAMSAP2
4483:CAMSAP1
4455:DYNLRB2
4450:DYNLRB1
4420:DYNC1I2
4415:DYNC1I1
4410:DYNC2H1
4405:DYNC1H1
4298:Dyneins
4022:TUBGCP6
4017:TUBGCP5
4012:TUBGCP4
4007:TUBGCP3
4002:TUBGCP2
3831:Synemin
3574:type II
3436:type II
3319:Keratin
3264:Filamin
3205:Destrin
3188:Cofilin
3149:Actinin
2720:Myosins
2637:of the
2541:3132387
2440:9546856
2419:Bibcode
2372:7069094
2323:6530524
2230:9239687
2179:9239687
2076:9883185
2055:Bibcode
2019:3523837
1996:Bibcode
1890:6868217
1861:Bibcode
1825:8371605
1804:Bibcode
1757:8728224
1474:Ensembl
1453:Ensembl
1425:CAMSAP1
1420:CAMSAP3
1249:of the
1222:neurons
1133:α-cells
1129:β-cells
1116:CAMSAP3
1035:protein
797:UniProt
752:Ensembl
691:Species
670:QuickGO
584:cytosol
427:utricle
314:pattern
88:CAMSAP2
72:1922434
47:CAMSAP2
40:Aliases
24:CAMSAP2
4762:SPTBN5
4757:SPTBN4
4752:SPTBN2
4747:SPTBN1
4737:SPTAN1
4572:Tektin
4465:DYNLT3
4460:DYNLT1
4445:DYNLL2
4440:DYNLL1
4387:DNALI1
4372:DNAH17
4367:DNAH14
4362:DNAH13
4357:DNAH12
4352:DNAH11
4347:DNAH10
4268:KIF26B
4263:KIF26A
4238:KIF21B
4233:KIF21A
4228:KIF20B
4223:KIF20A
4213:KIF18B
4208:KIF18A
4198:KIF16B
4183:KIF13B
4178:KIF13A
3977:TUBB4Q
3962:TUBB2C
3957:TUBB2B
3952:TUBB2A
3932:TUBA4A
3927:TUBA3E
3922:TUBA3D
3917:TUBA3C
3912:TUBA1C
3907:TUBA1B
3902:TUBA1A
3845:Type 5
3804:Nestin
3792:Type 4
3768:Desmin
3761:Type 3
3514:type I
3345:type I
3291:TRIOBP
2957:MYO18B
2952:MYO18A
2948:XVIII
2942:MYO15A
2677:Actins
2594:
2548:
2538:
2499:
2489:
2447:
2437:
2379:
2369:
2330:
2320:
2278:
2258:Neuron
2237:
2227:
2186:
2176:
2135:
2083:
2073:
2026:
2016:
1967:
1897:
1887:
1879:
1832:
1822:
1796:Nature
1764:
1754:
1675:
1625:
1575:
1388:CA19-9
1184:dimers
1060:CLASP1
989:search
987:PubMed
830:Q8C1B1
811:Q08AD1
707:Entrez
485:BioGPS
439:zygote
172:1q32.1
64:613775
4822:Talin
4805:MACF1
4773:Other
4732:SPTA1
4597:TEKT5
4592:TEKT4
4587:TEKT3
4582:TEKT2
4577:TEKT1
4560:DCTN1
4543:Other
4397:DNAL4
4392:DNAL1
4382:DNAI2
4377:DNAI1
4342:DNAH9
4337:DNAH8
4332:DNAH7
4327:DNAH6
4322:DNAH5
4317:DNAH3
4312:DNAH2
4307:DNAH1
4288:KIFC3
4283:KIFC2
4278:KIFC1
4273:KIF27
4258:KIF25
4253:KIF24
4248:KIF23
4243:KIF22
4218:KIF19
4203:KIF17
4193:KIF15
4188:KIF14
4173:KIF12
4168:KIF11
4148:KIF5C
4143:KIF5B
4138:KIF5A
4133:KIF4B
4128:KIF4A
4123:KIF3C
4118:KIF3B
4113:KIF2C
4108:KIF2A
4103:KIF1B
4098:KIF1A
4070:MAP1B
4065:MAP1A
4032:TUBE1
4027:TUBD1
3997:TUBG2
3992:TUBG1
3987:TUBB8
3982:TUBB6
3972:TUBB4
3967:TUBB3
3947:TUBB1
3937:TUBA8
3286:Espin
3247:Other
3234:Titin
3040:Other
3029:MYLL1
3024:MYLK2
3014:MYLIP
2999:MYL6B
2932:MYO10
2922:MYO9B
2917:MYO9A
2907:MYO7B
2902:MYO7A
2882:MYO5C
2877:MYO5B
2872:MYO5A
2862:MYO3B
2857:MYO3A
2847:MYH16
2842:MYH15
2837:MYH14
2832:MYH13
2827:MYH11
2822:MYH10
2807:MYH7B
2766:MYO1H
2761:MYO1G
2756:MYO1F
2751:MYO1E
2746:MYO1D
2741:MYO1C
2736:MYO1B
2731:MYO1A
2646:Human
2207:eLife
2156:eLife
1367:with
1336:MMP-1
1328:MMP-1
1324:c-Jun
1296:c-Jun
1052:AKAP9
1048:Golgi
1033:is a
740:67886
721:23271
700:Mouse
695:Human
666:Amigo
459:fossa
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
80:18927
4906:ParM
4901:MreB
4896:FtsZ
4856:ACF7
4849:PKP2
4844:PKP1
4827:TLN1
4742:SPTB
4720:ANK3
4715:ANK2
4710:ANK1
4619:DNM3
4614:DNM2
4609:DNM1
4513:PCM1
4163:KIF9
4158:KIF7
4153:KIF6
4080:MAP4
4075:MAP2
4042:MAPs
3942:TUBB
3885:MAPs
3883:and
3824:NEFH
3819:NEFM
3814:NEFL
3773:GFAP
3421:none
3279:FLNC
3274:FLNB
3269:FLNA
3019:MYLK
3009:MYL9
3004:MYL7
2994:MYL6
2989:MYL5
2984:MYL4
2979:MYL3
2974:MYL2
2969:MYL1
2898:VII
2892:MYO6
2853:III
2817:MYH9
2812:MYH8
2802:MYH7
2797:MYH6
2792:MYH4
2787:MYH3
2782:MYH2
2777:MYH1
2659:ABPs
2657:and
2592:PMID
2546:PMID
2497:PMID
2445:PMID
2377:PMID
2328:PMID
2276:PMID
2235:PMID
2184:PMID
2133:PMID
2081:PMID
2024:PMID
1965:PMID
1895:PMID
1877:ISSN
1830:PMID
1762:PMID
1673:PMID
1623:PMID
1573:PMID
1402:and
1386:and
1300:Rac1
1226:MTOC
1214:axon
1039:gene
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
4670:GAN
4653:APC
4060:EB3
4055:EB2
4050:EB1
3856:A/C
3539:33B
3534:33A
2938:XV
2913:IX
2888:VI
2773:II
2582:doi
2536:PMC
2528:doi
2487:PMC
2479:doi
2435:PMC
2427:doi
2367:PMC
2359:doi
2318:PMC
2310:doi
2306:160
2266:doi
2225:PMC
2215:doi
2174:PMC
2164:doi
2123:doi
2071:PMC
2063:doi
2014:PMC
2004:doi
1992:109
1955:doi
1885:PMC
1869:doi
1820:PMC
1812:doi
1800:596
1752:PMC
1744:doi
1665:doi
1615:doi
1565:doi
1394:of
1320:JNK
1304:JNK
493:n/a
290:End
189:End
92:OMA
68:MGI
4937::
3866:B2
3861:B1
3854::
3730:80
3725:79
3720:78
3715:77
3710:76
3705:75
3700:74
3695:73
3690:72
3685:71
3669:40
3664:39
3659:28
3654:27
3649:26
3644:25
3639:24
3634:23
3609:86
3604:85
3599:84
3594:83
3589:82
3584:81
3564:38
3559:37
3554:36
3549:35
3544:34
3529:32
3524:31
3481:6C
3476:6B
3471:6A
3451:2A
3426:21
3414:18
3400:20
3395:19
3390:17
3385:16
3380:15
3375:14
3370:13
3365:12
3360:10
2964:LC
2928:X
2868:V
2727:I
2710:G2
2705:G1
2700:C1
2690:A2
2685:A1
2590:.
2578:26
2576:.
2572:.
2544:.
2534:.
2524:63
2522:.
2518:.
2495:.
2485:.
2475:43
2469:.
2457:^
2443:.
2433:.
2425:.
2415:12
2413:.
2409:.
2383:.
2375:.
2365:.
2355:10
2353:.
2349:.
2326:.
2316:.
2304:.
2300:.
2288:^
2274:.
2262:82
2260:.
2256:.
2233:.
2223:.
2213:.
2211:11
2209:.
2205:.
2182:.
2172:.
2160:11
2158:.
2154:.
2131:.
2119:28
2117:.
2113:.
2087:.
2079:.
2069:.
2061:.
2051:26
2049:.
2045:.
2022:.
2012:.
2002:.
1990:.
1986:.
1963:.
1951:28
1949:.
1945:.
1919:.
1915:.
1893:.
1883:.
1875:.
1867:.
1857:10
1855:.
1851:.
1828:.
1818:.
1810:.
1798:.
1794:.
1768:.
1760:.
1750:.
1740:50
1738:.
1734:.
1708:.
1704:.
1679:.
1671:.
1661:39
1659:.
1655:.
1629:.
1621:.
1611:26
1609:.
1605:.
1579:.
1571:.
1561:91
1559:.
1555:.
1529:.
1525:.
1507:.
1489:.
1460:^
1439:^
1310:.
1058:.
668:/
296:bp
283:bp
195:bp
182:bp
90:;
86::
82:;
78::
74:;
70::
66:;
62::
3576:/
3516:/
3491:8
3486:7
3466:5
3461:4
3456:3
3446:1
3438:/
3355:9
3347:/
3326:)
3321:,
3317:(
3227:2
3222:1
3198:2
3193:1
3169:4
3164:3
3159:2
3154:1
3140:4
3135:3
3130:2
3125:1
3113:3
3110:2
3107:1
3104:I
3099:2
3096:1
3093:C
3088:3
3085:2
3082:1
3079:T
3067:4
3062:3
3057:2
3052:1
2768:)
2695:B
2627:e
2620:t
2613:v
2598:.
2584::
2552:.
2530::
2503:.
2481::
2451:.
2429::
2421::
2394:.
2361::
2334:.
2312::
2282:.
2268::
2241:.
2217::
2190:.
2166::
2139:.
2125::
2098:.
2065::
2057::
2030:.
2006::
1998::
1971:.
1957::
1930:.
1901:.
1871::
1863::
1836:.
1814::
1806::
1779:.
1746::
1719:.
1690:.
1667::
1640:.
1617::
1590:.
1567::
1540:.
1511:.
1493:.
1326:/
1322:/
1302:/
214:)
111:)
94::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
