347:
324:
221:
246:
3805:
3790:
3775:
3820:
3760:
605:
598:
353:
252:
7860:
1603:
42:
68:
1524:
Hematopoietic progenitors expressing CD10 are considered "common lymphoid progenitors", which means they can differentiate into T, B or natural killer cells. CD10 is of use in hematological diagnosis since it is expressed by early B, pro-B and pre-B lymphocytes, and by lymph node
1565:. CD10 is found on non-T ALL cells, which derive from pre-B lymphocytes, and in germinal center-related non-Hodgkin lymphoma such as Burkitt lymphoma and follicular lymphoma, but not on leukemia cells or lymphomas, which originate in more mature B cells.
2298:
Iwata N, Tsubuki S, Takaki Y, Watanabe K, Sekiguchi M, Hosoki E, et al. (February 2000). "Identification of the major Abeta1-42-degrading catabolic pathway in brain parenchyma: suppression leads to biochemical and pathological deposition".
3207:
Córdoba A, Guerrero D, Larrinaga B, Iglesias ME, Arrechea MA, Yanguas JI (2009). "Bcl-2 and CD10 expression in the differential diagnosis of trichoblastoma, basal cell carcinoma, and basal cell carcinoma with follicular differentiation".
3116:
Yasir S, Herrera L, Gomez-Fernandez C, Reis IM, Umar S, Leveillee R, et al. (2012). "CD10 and CK7/RON- immunophenotype distinguishes renal cell carcinoma, conventional type with eosinophilic morphology from its mimickers".
1577:
show both
Alzheimer's-like behavioral impairment and amyloid-beta deposition in the brain, providing strong evidence for the protein's association with the Alzheimer's disease process. Because neprilysin is thought to be the
2039:
3163:
Notohara K, Hamazaki S, Tsukayama C, Nakamoto S, Kawabata K, Mizobuchi K, et al. (2000). "Solid-pseudopapillary tumor of the pancreas: immunohistochemical localization of neuroendocrine markers and CD10".
2254:
Madani R, Poirier R, Wolfer DP, Welzl H, Groscurth P, Lipp HP, et al. (December 2006). "Lack of neprilysin suffices to generate murine amyloid-like deposits in the brain and behavioral deficit in vivo".
1520:
antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.
5897:
2988:
Yuan CM, Vergilio JA, Zhao XF, Smith TK, Harris NL, Bagg A (2005). "CD10 and BCL6 expression in the diagnosis of angioimmunoblastic T-cell lymphoma: utility of detecting CD10+ T cells by flow cytometry".
1593:
damage, known to be a causative factor in
Alzheimer's disease; higher levels of inappropriately oxidized neprilysin have been found in Alzheimer's patients compared to cognitively normal elderly people.
2708:"Differentiating between Burkitt lymphoma and CD10+ diffuse large B-cell lymphoma: the role of commonly used flow cytometry cell markers and the application of a multiparameter scoring system"
4721:
1960:
CD10 expression is strongly correlated with high tumor grade and stage in urothelial carcinoma of the bladder. CD10 may be associated with tumor progression in bladder cancer pathogenesis.
3860:
5890:
360:
259:
3804:
3789:
3774:
2896:
Fabiani B, Delmer A, Lepage E, Guettier C, Petrella T, Brière J, et al. (2004). "CD10 expression in diffuse large B-cell lymphomas does not influence survival".
2808:"A cytomorphological and immunohistochemical profile of aggressive B-cell lymphoma: high clinical impact of a cumulative immunohistochemical outcome predictor score"
7184:
5883:
3819:
4711:
3759:
3526:
Weinreb I, Cunningham KS, Perez-Ordoñez B, Hwang DM (2009). "CD10 is expressed in most epithelioid hemangioendotheliomas: a potential diagnostic pitfall".
3563:"Immunoreactivity of CD10 and inhibin alpha in differentiating hemangioblastoma of central nervous system from metastatic clear cell renal cell carcinoma"
3024:
Attygalle AD, Diss TC, Munson P, Isaacson PG, Du MQ, Dogan A (2004). "CD10 expression in extranodal dissemination of angioimmunoblastic T-cell lymphoma".
1888:
CD10 distinguishes renal cell carcinoma, conventional type with eosinophilic morphology from its mimickers. Chromophobe carcinoma and oncocytoma are CD10.
4691:
3707:
3487:"Combined analysis of efficacy: the addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer"
1028:
2857:"Clinicopathologic analysis of CD10+ and CD10- diffuse large B-cell lymphoma: Identification of a high-risk subset with coexpression of CD10 and bcl-2"
1009:
182:
65:
5553:
3877:
3853:
2459:
Oefner C, Roques BP, Fournie-Zaluski MC, Dale GE (February 2004). "Structural analysis of neprilysin with various specific and potent inhibitors".
6339:
6201:
5284:
1909:
5272:
5050:
2712:
7526:
5336:
5331:
5277:
5057:
3838:
3739:
2118:
3438:"CD10 is a sensitive and diagnostically useful immunohistochemical marker of normal endometrial stroma and of endometrial stromal neoplasms"
2100:
7880:
4790:
4716:
3846:
3253:"Value of CD10 Expression in Differentiating Cutaneous Basal from Squamous Cell Carcinomas and Basal Cell Carcinoma from Trichoepithelioma"
1589:
have been identified that increase the enzyme's activity level. Declining neprilysin activity with increasing age may also be explained by
7213:
7177:
5819:
5814:
5809:
5804:
4731:
2547:"Neutral endopeptidase: variable expression in human lung, inactivation in lung cancer, and modulation of peptide-induced calcium flux"
1304:
346:
6531:
1864:
1530:
1930:(CD10 peritumoral stromal staining), basal cell carcinoma with follicular differentiation (CD10 stromal and epithelial staining) and
7579:
5784:
1311:
3612:"Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review"
323:
6778:
6717:
5020:
2014:
7885:
6957:
6549:
5588:
5082:
4768:
2087:
2066:
1882:
6853:
2576:
Alasbahi R, Melzig MF (January 2008). "Screening of some Yemeni medicinal plants for inhibitory activity against peptidases".
2383:
Wang DS, Iwata N, Hama E, Saido TC, Dickson DW (October 2003). "Oxidized neprilysin in aging and
Alzheimer's disease brains".
7170:
5227:
4763:
7735:
2083:
245:
220:
6947:
6617:
6089:
5724:
5196:
5191:
5136:
4870:
4319:
1799:
1542:
7850:
2062:
7531:
6900:
6831:
6803:
6576:
5418:
5141:
1898:
1837:
1554:
1538:
162:
1999:
1820:
Other dual inhibitors of NEP with ACE/angiotensin receptor were (in 2003) being developed by pharmaceutical companies.
6332:
4736:
1978:
1855:
Marker for germinal center phenotype (CD10, HGAL, BCL6, CD38) are considered a favorable prognostic factor, but CD10,
1988:
7425:
7420:
6942:
5906:
5448:
3873:
1741:
1643:
1517:
359:
258:
7720:
7836:
7823:
7810:
7797:
7784:
7771:
7758:
7204:
6937:
4314:
3732:
1516:
Neprilysin is expressed in a wide variety of tissues and is particularly abundant in kidney. It is also a common
7730:
352:
251:
7684:
7627:
7541:
7358:
7201:
6732:
6707:
6679:
6607:
6437:
6428:
5498:
4393:
3677:
1905:
1073:
170:
2004:
1972:
CD10 expression might be one of the characteristics of müllerian system-derived neoplastic mesenchymal cells.
1509:, the neprilysin ectodomain is released into the extracellular domain after it has been transported from the
7632:
6298:
5462:
1994:
1946:
1931:
1054:
7895:
7000:
6811:
6325:
6279:
6056:
6046:
5969:
4805:
4800:
4795:
4785:
4092:
4020:
2427:
1938:
1859:
tumors could have poorer survival. For some authors, CD10 expression in DLBCL does not influence survival.
1582:
in amyloid beta degradation, it has been considered a potential therapeutic target; compounds such as the
1562:
1550:
1502:
7653:
7572:
7516:
6845:
6712:
5959:
4149:
4067:
3389:"Expression of CD10 in malignant müllerian mixed tumors and adenosarcomas: an immunohistochemical study"
2155:"Human T, B, natural killer, and dendritic cells arise from a common bone marrow progenitor cell subset"
1653:; however, the relationship between neprilysin expression and carcinogenesis remains obscure. In cancer
1614:
Neprilysin is also associated with other biochemical processes, and is particularly highly expressed in
7725:
1954:
7197:
6471:
5386:
5099:
3725:
2024:
1923:
1917:
1773:
1755:
1657:
studies, the neprilysin gene is often referred to as CD10 or CALLA. In some types of cancer, such as
1558:
234:
2423:"A New Class of Inhibitors for the Metalloprotease Neprilysin Based on a Central Imidazole Scaffold"
153:, CALLA, CD10, NEP, SFE, membrane metallo-endopeptidase, membrane metalloendopeptidase, CMT2T, SCA43
149:
7689:
6792:
5413:
5232:
2545:
Cohen AJ, Bunn PA, Franklin W, Magill-Solc C, Hartmann C, Helfrich B, et al. (February 1996).
1982:
1843:
1546:
1287:
1279:
1275:
1254:
1250:
1240:
1204:
1200:
1196:
1171:
1167:
1157:
2941:"CD10 and ICOS expression by multiparametric flow cytometry in angioimmunoblastic T-cell lymphoma"
7890:
7622:
4820:
4554:
3592:
3467:
3418:
3233:
3189:
3142:
3098:
3049:
2970:
2921:
2788:
2688:
2653:
2324:
2280:
1677:
1579:
194:
1283:
1236:
1232:
1228:
1224:
1192:
1153:
1149:
1145:
1141:
7162:
2421:
Sahli S, Stump B, Welti T, Schweizer WB, Diederich R, Blum-Kaelin D, et al. (April 2005).
6905:
6892:
6817:
6740:
6694:
6666:
6502:
3684:
3643:
3584:
3543:
3508:
3459:
3410:
3366:
3315:
3274:
3225:
3181:
3134:
3090:
3041:
3006:
2962:
2913:
2878:
2837:
2780:
2739:
2645:
2593:
2558:
2527:
2476:
2400:
2365:
2316:
2272:
2236:
2176:
142:
58:
2939:
Baseggio L, Traverse-Glehen A, Berger F, Ffrench M, Jallades L, Morel D, et al. (2011).
1465:
at the amino side of hydrophobic residues and inactivates several peptide hormones including
7668:
7663:
7637:
7565:
7465:
7139:
6448:
6389:
6019:
5593:
5326:
5247:
4810:
4003:
3929:
3633:
3623:
3574:
3535:
3498:
3449:
3400:
3356:
3346:
3305:
3264:
3217:
3173:
3126:
3080:
3033:
2998:
2952:
2905:
2868:
2827:
2819:
2770:
2759:"Evaluation of immunophenotype in diffuse large B-cell lymphoma and its impact on prognosis"
2729:
2721:
2680:
2635:
2627:
2585:
2517:
2507:
2494:
Velazquez EF, Yancovitz M, Pavlick A, Berman R, Shapiro R, Bogunovic D, et al. (2007).
2468:
2436:
2392:
2355:
2308:
2264:
2226:
2195:
2166:
2020:
1893:
1725:
1627:
1534:
1526:
1506:
1369:
439:
370:
314:
269:
3668:
2614:
McMurray JJ, Packer M, Desai AS, Gong J, Lefkowitz MP, Rizkala AR, et al. (Sep 2014).
604:
597:
7715:
7699:
7612:
7221:
6992:
6929:
6867:
6825:
6632:
6456:
5653:
4189:
4184:
4107:
1583:
1510:
1494:
1458:
414:
2546:
190:
5875:
7864:
7753:
7694:
7010:
6769:
6484:
6415:
6186:
6015:
5974:
5438:
4860:
4371:
4174:
3638:
3611:
3361:
3334:
3269:
3252:
3069:"Benign CD10-positive T cells in reactive lymphoid proliferations and B-cell lymphomas"
2832:
2807:
2734:
2707:
2522:
2495:
1927:
1728:
agents that act by preventing neprilysin's activity against signaling peptides such as
1630:
agents that act by preventing neprilysin's activity against signaling peptides such as
1574:
3673:
3405:
3388:
3085:
3068:
943:
938:
933:
928:
923:
918:
913:
908:
903:
898:
893:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
711:
706:
701:
696:
691:
686:
681:
676:
671:
666:
661:
656:
651:
646:
7874:
7658:
7617:
7033:
6494:
6479:
6423:
6381:
6158:
6130:
5408:
4865:
3956:
3711:
3693:
3454:
3437:
3237:
3221:
3177:
3037:
2360:
2343:
2171:
2154:
1748:
1498:
633:
3596:
3471:
3422:
3102:
3053:
2974:
2925:
2692:
2671:
Venugopal J (2003). "Pharmacological modulation of the natriuretic peptide system".
2328:
2284:
7607:
6859:
6839:
6571:
6559:
6348:
5764:
5072:
5062:
4593:
4559:
3193:
3146:
2792:
1778:
1700:
1649:
Associations have been observed between neprilysin expression and various types of
1586:
1490:
432:
211:
3002:
2757:
Berglund M, Thunberg U, Amini RM, Book M, Roos G, Erlanson M, et al. (2005).
2615:
174:
3130:
2657:
2231:
2214:
198:
7831:
7766:
7602:
7536:
7521:
7366:
7118:
7056:
6645:
6636:
6599:
6541:
6523:
5981:
5774:
5423:
5201:
5176:
4875:
4497:
4423:
3897:
3310:
3293:
2873:
2856:
2806:
Höller S, Horn H, Lohr A, Mäder U, Katzenberger T, Kalla J, et al. (2009).
2123:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2105:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1814:
1795:
1733:
1669:
1635:
1478:
1474:
7859:
3813:: STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
3798:: STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
3783:: STRUCTURAL ANALYSIS OF NEPRILYSIN WITH VARIOUS SPECIFIC AND POTENT INHIBITORS
3485:
Kabbinavar FF, Hambleton J, Mass RD, Hurwitz HI, Bergsland E, Sarkar S (2005).
2684:
2396:
515:
7383:
7109:
6432:
5990:
5932:
5915:
5704:
5428:
5109:
4850:
4726:
4359:
4354:
4349:
4204:
3579:
3562:
2957:
2940:
2909:
2823:
2775:
2758:
2472:
1803:
1790:
1765:
1737:
1729:
1712:) were found able to inhibit the enzymatic activity of neutral endopeptidase.
1658:
1639:
1631:
1602:
1486:
1470:
331:
228:
178:
41:
2725:
7805:
7779:
7105:
6612:
6461:
5543:
5538:
5533:
5523:
5518:
5513:
5508:
3828:: Crystal Structure of human NEP complexed with an imidazopyridine inhibitor
3503:
3486:
1809:
1759:
1721:
1693:
1686:
1673:
1661:
1654:
1623:
1590:
973:
575:
453:
398:
385:
297:
284:
186:
3647:
3628:
3588:
3547:
3512:
3463:
3414:
3370:
3351:
3319:
3278:
3229:
3185:
3138:
3094:
3045:
3010:
2966:
2917:
2882:
2841:
2784:
2743:
2649:
2597:
2589:
2531:
2480:
2441:
2422:
2404:
2369:
2320:
2276:
2240:
2631:
2562:
2512:
2180:
1867:(AITL) are CD10 and distinguishes AITL from other T cell lymphomas (CD10)
1672:, neprilysin is downregulated, and thus unable to modulate the pro-growth
1351:
1346:
7546:
7348:
7343:
7338:
7193:
7095:
7061:
7046:
6563:
6363:
5849:
5749:
5563:
5548:
4751:
4746:
4654:
4344:
2139:
1942:
1681:
1665:
1482:
1466:
1335:
1122:
1103:
1099:
3768:: STRUCTURE OF HUMAN NEUTRAL ENDOPEPTIDASE COMPLEXED WITH PHOSPHORAMIDON
3539:
7333:
7328:
7323:
7318:
7313:
7308:
7303:
7087:
7041:
6977:
6873:
6210:
6144:
6076:
5799:
5794:
5789:
5689:
5503:
5493:
5320:
5299:
5294:
5262:
5067:
4987:
4982:
4977:
4972:
4967:
4885:
4578:
4418:
4413:
4408:
4403:
4398:
3869:
3698:
3688:
2706:
McGowan P, Nelles N, Wimmer, J, Williams D, Wen J, et al. (2012).
2640:
2040:
List of histologic stains that aid in diagnosis of cutaneous conditions
1769:
1707:
1462:
1085:
1040:
2268:
119:
115:
111:
107:
103:
99:
95:
91:
87:
7818:
7588:
7470:
7298:
7293:
7288:
7283:
7278:
7273:
7268:
7263:
7241:
7236:
7231:
7147:
6962:
6909:
6784:
6744:
6702:
6674:
6153:
6007:
5924:
5739:
5699:
5684:
5668:
5663:
5643:
5638:
5573:
5381:
5351:
5315:
5306:
5119:
5087:
4951:
4946:
4916:
4895:
4855:
4815:
4681:
4659:
4618:
4542:
4537:
4532:
4527:
4522:
4517:
4386:
4381:
4376:
4324:
4309:
4179:
4169:
4132:
4127:
4045:
4040:
3664:
2616:"Angiotensin-neprilysin inhibition versus enalapril in heart failure"
1784:
1650:
1615:
1607:
1446:
1319:
995:
2496:"Clinical relevance of neutral endopeptidase (NEP/CD10) in melanoma"
17:
7792:
7495:
7490:
7485:
7480:
7475:
7460:
7455:
7450:
7445:
7440:
7435:
7430:
7415:
7410:
7258:
7253:
7248:
7226:
7066:
7051:
7023:
7018:
6982:
6967:
6952:
6919:
6881:
6722:
6684:
6622:
6394:
6246:
6166:
5941:
5864:
5839:
5759:
5754:
5744:
5734:
5719:
5714:
5709:
5694:
5648:
5633:
5598:
5583:
5578:
5568:
5488:
5483:
5478:
5457:
5453:
5443:
5356:
5257:
5252:
5211:
5161:
5156:
5151:
5146:
5131:
5124:
5104:
5092:
5035:
5030:
5025:
5015:
5010:
5003:
4941:
4931:
4926:
4921:
4911:
4890:
4880:
4845:
4840:
4835:
4830:
4825:
4780:
4775:
4741:
4706:
4701:
4696:
4686:
4674:
4669:
4649:
4644:
4639:
4634:
4588:
4480:
4475:
4294:
4278:
4271:
4266:
4261:
4256:
4251:
4246:
4221:
4199:
4194:
4087:
4013:
4008:
3998:
3333:
Bahadir B, Behzatoglu K, Bektas S, Bozkurt ER, Ozdamar SO (2009).
2312:
1676:
signaling of cancer cells via secreted peptides such as mammalian
1622:
tissues. Inhibitors have been designed with the aim of developing
1601:
958:
954:
7405:
7400:
7393:
7388:
7376:
7371:
6972:
6914:
6798:
6317:
6306:
6284:
6259:
6254:
6236:
6232:
6227:
6222:
6218:
6191:
6181:
6176:
6171:
6094:
6084:
6066:
6061:
6051:
5985:
5964:
5954:
5949:
5859:
5854:
5844:
5834:
5829:
5824:
5779:
5769:
5729:
5658:
5628:
5623:
5618:
5613:
5608:
5603:
5558:
5528:
5433:
5401:
5396:
5376:
5366:
5361:
5346:
5341:
5242:
5237:
5206:
5186:
5181:
5171:
5166:
5045:
4998:
4958:
4613:
4608:
4603:
4598:
4583:
4574:
4569:
4564:
4549:
4507:
4502:
4492:
4487:
4470:
4465:
4460:
4455:
4450:
4445:
4440:
4435:
4430:
4366:
4339:
4334:
4329:
4304:
4299:
4236:
4231:
4226:
4216:
4211:
4164:
4159:
4154:
4144:
4139:
4122:
4117:
4112:
4102:
4097:
4082:
4077:
4072:
4062:
4057:
4052:
4035:
4030:
4025:
3976:
3944:
3939:
3934:
3917:
3912:
3907:
3902:
1856:
1619:
1454:
166:
7561:
7166:
6321:
5879:
3842:
3721:
613:
6110:
6041:
6036:
6031:
6024:
5371:
3983:
3971:
3966:
3961:
3951:
3924:
3892:
3717:
3683:
Overview of all the structural information available in the
2344:"Metabolism of amyloid-beta peptide and Alzheimer's disease"
1668:, neprilysin is overexpressed; in other types, most notably
1529:. Hematologic diseases in which it is positive include ALL,
3294:"CD10 immunohistochemical staining in urothelial neoplasms"
1828:
CD10 is used in clinical pathology for diagnostic purpose.
1396:
1378:
7557:
1787:, an enkephalinase inhibitor, used in scientific research.
1720:
Inhibitors have been designed with the aim of developing
1402:
1387:
3335:"CD10 expression in urothelial carcinoma of the bladder"
422:
1802:) developed by BMS did not receive FDA approval due to
3251:
Sari Aslani F, Akbarzadeh-Jahromi M, Jowkar F (2013).
1549:(10%), and myeloma (some). It tends to be negative in
944:
positive regulation of long-term synaptic potentiation
7848:
3667:
online database for peptidases and their inhibitors:
1405:
1399:
1375:
1372:
587:
1393:
1384:
1381:
939:
amyloid-beta clearance by cellular catabolic process
7744:
7708:
7677:
7646:
7595:
7504:
7357:
7212:
7138:
7131:
7104:
7086:
7079:
7032:
7009:
6991:
6928:
6891:
6768:
6757:
6731:
6693:
6665:
6658:
6631:
6598:
6589:
6558:
6540:
6522:
6515:
6493:
6470:
6447:
6414:
6407:
6380:
6362:
6355:
6297:
6272:
6245:
6209:
6200:
6152:
6143:
6123:
6103:
6075:
6006:
5999:
5923:
5914:
5677:
5471:
5220:
4904:
4627:
4287:
3885:
1390:
1268:
1223:
1185:
1140:
2079:
2077:
2075:
2058:
2056:
2054:
1606:Neprilysin immunohistochemical staining of normal
1758:(Entresto/LCZ696), which has been tested against
369:
268:
2153:Galy A, Travis M, Cen D, Chen B (October 1995).
1852:CD10 diffuse large B cell lymphoma (CD10 DLBCL)
3387:Mikami Y, Hata S, Kiyokawa T, Manabe T (2002).
3382:
3380:
3158:
3156:
2855:Xu Y, McKenna RW, Molberg KH, Kroft SH (2001).
2609:
2607:
2342:Iwata N, Higuchi M, Saido TC (November 2005).
2084:GRCm38: Ensembl release 89: ENSMUSG00000027820
7573:
7178:
6333:
5891:
3854:
3733:
3436:McCluggage WG, Sumathi VP, Maxwell P (2001).
2140:"Entrez Gene: Membrane metallo-endopeptidase"
1545:(variable), follicular center cells (70%),
8:
1684:. Some plant extracts (methanol extracts of
2063:GRCh38: Ensembl release 89: ENSG00000196549
1439:common acute lymphoblastic leukemia antigen
7580:
7566:
7558:
7185:
7171:
7163:
7135:
7083:
6765:
6662:
6595:
6519:
6411:
6359:
6340:
6326:
6318:
6206:
6149:
6003:
5920:
5898:
5884:
5876:
3861:
3847:
3839:
3740:
3726:
3718:
3708:United States National Library of Medicine
1220:
1137:
969:
629:
410:
309:
206:
76:
3878:list of human clusters of differentiation
3676:at the U.S. National Library of Medicine
3637:
3627:
3578:
3502:
3453:
3404:
3360:
3350:
3309:
3268:
3084:
2956:
2872:
2831:
2774:
2733:
2639:
2521:
2511:
2454:
2452:
2440:
2359:
2230:
2170:
1846:(follicle centre cell lymphoma) are CD10.
3706:This article incorporates text from the
2416:
2414:
2213:Papandreou CN, Nanus DM (January 2010).
2134:
2132:
7855:
3755:
3067:Cook JR, Craig FE, Swerdlow SH (2003).
2050:
1910:intraductal papillary mucinous neoplasm
1781:(LBQ657), the active form of sacubitril
27:Mammalian protein found in Homo sapiens
3298:American Journal of Clinical Pathology
2861:American Journal of Clinical Pathology
2713:American Journal of Clinical Pathology
2215:"Is methylation the key to CD10 loss?"
854:cellular response to cytokine stimulus
31:
7527:Pregnancy-associated plasma protein A
2673:Expert Opinion on Therapeutic Patents
738:integral component of plasma membrane
374:
335:
330:
273:
232:
227:
7:
550:vestibular membrane of cochlear duct
3119:Appl. Immunohistochem. Mol. Morphol
2620:The New England Journal of Medicine
924:positive regulation of neurogenesis
1865:Angioimmunoblastic T cell lymphoma
1531:angioimmunoblastic T cell lymphoma
1501:has been implicated as a cause of
1265:
1182:
1113:
1090:
1064:
1045:
1019:
1000:
592:
510:
448:
427:
25:
3406:10.1097/01.MP.0000026058.33869.DB
3086:10.1097/01.MP.0000084630.64243.D1
2000:Uterine high-grade leiomyosarcoma
1985:are usually CD10, but can be CD10
1912:of branch duct type (CD10/CK20-).
1449:that in humans is encoded by the
702:protein homodimerization activity
7858:
6779:Surface epithelial-stromal tumor
6718:Tumor-associated glycoprotein 72
3818:
3803:
3788:
3773:
3758:
3455:10.1046/j.1365-2559.2001.01215.x
3222:10.1111/j.1365-4632.2009.04076.x
3178:10.1097/00000478-200010000-00005
3038:10.1097/00000478-200401000-00005
2361:10.1016/j.pharmthera.2005.03.010
2015:Epithelioid hemangioendothelioma
1926:(CD10 epithelial staining) from
1849:Burkitt Lymphoma cells are CD10.
1368:
603:
596:
358:
351:
345:
322:
257:
250:
244:
219:
40:
6958:Early prostate cancer antigen-2
6550:Glial fibrillary acidic protein
1989:Malignant müllerian mixed tumor
1883:Clear cell renal cell carcinoma
1870:Some benign T cells can be CD10
1762:in patients with heart failure.
3610:Yin WH, Li J, Chan JK (2012).
1415:membrane metallo-endopeptidase
884:amyloid-beta metabolic process
758:integral component of membrane
614:More reference expression data
576:More reference expression data
1:
6948:Glutamate carboxypeptidase II
3292:Murali R, Delprado W (2005).
3003:10.1016/j.humpath.2005.05.008
2385:Biochem. Biophys. Res. Commun
2202:. PathologyOutlines.com, Inc.
1899:Solid pseudopapillary tumours
1800:angiotensin-converting enzyme
1543:diffuse large B-cell lymphoma
1431:cluster of differentiation 10
687:metalloendopeptidase activity
534:vestibular sensory epithelium
343:
242:
7532:Bone morphogenetic protein 1
6577:Melanoma inhibitory activity
3131:10.1097/PAI.0b013e31823fecd3
2232:10.1097/MPH.0b013e3181c74aca
2172:10.1016/1074-7613(95)90175-2
2023:is usually CD10 (metastatic
1838:Acute lymphoblastic leukemia
1705:, and an aqueous extract of
1555:chronic lymphocytic leukemia
1539:chronic myelogenous leukemia
874:creatinine metabolic process
7881:Genes on human chromosome 3
3874:clusters of differentiation
3311:10.1309/04BH-F6A8-0BQM-H7HT
2874:10.1309/J7RN-UXAY-55GX-BUNK
1979:Endometrial stromal sarcoma
1798:(dual inhibitor of NEP and
1747:Some are intended to treat
476:stromal cell of endometrium
7912:
6943:Prostatic acid phosphatase
6854:Sertoli–Leydig cell tumour
5907:Cluster of differentiation
2685:10.1517/13543776.13.9.1389
2397:10.1016/j.bbrc.2003.09.003
2219:J. Pediatr. Hematol. Oncol
1934:(strong stromal staining).
1832:In lymphomas and leukemias
1742:atrial natriuretic peptide
1644:atrial natriuretic peptide
1518:acute lymphocytic leukemia
894:sensory perception of pain
793:secretory granule membrane
788:neuron projection terminus
697:phosphatidylserine binding
7736:Michaelis–Menten kinetics
7359:Matrix metalloproteinases
6938:Prostate-specific antigen
6618:Autocrine motility factor
3753:
3580:10.1038/modpathol.3800351
2958:10.1038/modpathol.2011.53
2910:10.1007/s00428-004-1129-7
2824:10.1007/s12308-009-0044-x
2776:10.1038/modpathol.3800396
2473:10.1107/S0907444903027410
2119:"Mouse PubMed Reference:"
2101:"Human PubMed Reference:"
1975:Normal endometrial stroma
1937:CD10 differentiates CD10
1906:mucinous cystic neoplasms
1350:
1345:
1341:
1334:
1318:
1305:Chr 3: 155.02 – 155.18 Mb
1299:
1272:
1247:
1216:
1189:
1164:
1133:
1120:
1116:
1097:
1093:
1084:
1071:
1067:
1052:
1048:
1039:
1026:
1022:
1007:
1003:
994:
979:
972:
968:
952:
879:peptide metabolic process
869:cellular response to UV-A
849:cellular response to UV-B
692:metallopeptidase activity
632:
628:
611:
595:
586:
573:
522:
513:
460:
451:
421:
413:
409:
392:
379:
342:
321:
312:
308:
291:
278:
241:
218:
209:
205:
160:
157:
147:
140:
135:
84:
79:
62:
57:
52:
48:
39:
34:
7628:Diffusion-limited enzyme
7542:Insulin-degrading enzyme
6733:Hepatocellular carcinoma
6708:Carcinoembryonic antigen
6680:Carcinoembryonic antigen
6608:Carcinoembryonic antigen
6438:Carcinoembryonic antigen
6429:Medullary thyroid cancer
3678:Medical Subject Headings
3561:Jung SM, Kuo TT (2005).
2726:10.1309/AJCP3FEPX5BEEKGX
2005:Uterine rhabdomyosarcoma
1772:which is a component of
1541:in blast crisis (90%),
899:neutrophil degranulation
3504:10.1200/JCO.2005.00.232
1957:express CD10 (42-67%).
1947:squamous cell carcinoma
1941:from CD10 spindle cell
1932:squamous cell carcinoma
1922:CD10 may differentiate
1569:Amyloid beta regulation
1493:peptide whose abnormal
1489:. It also degrades the
1312:Chr 3: 63.15 – 63.29 Mb
929:neuropeptide processing
707:oligopeptidase activity
554:external carotid artery
3629:10.1186/1746-1596-7-39
3528:Arch. Pathol. Lab. Med
3352:10.1186/1746-1596-4-38
2590:10.1055/s-2008-1047849
2442:10.1002/hlca.200590050
2428:Helvetica Chimica Acta
2194:Singh C (2011-02-25).
1995:Müllerian adenosarcoma
1939:atypical fibroxanthoma
1611:
1563:marginal zone lymphoma
1551:acute myeloid leukemia
1507:membrane-bound protein
1453:gene. Neprilysin is a
934:amyloid-beta clearance
864:replicative senescence
844:angiotensin maturation
667:endopeptidase activity
472:metanephric glomerulus
7721:Eadie–Hofstee diagram
7654:Allosteric regulation
7517:Procollagen peptidase
7198:metalloendopeptidases
6472:Neuroendocrine tumors
2632:10.1056/NEJMoa1409077
2513:10.1186/1479-5876-5-2
1840:(ALL) cells are CD10.
1605:
1573:Neprilysin-deficient
1513:to the cell surface.
1423:neutral endopeptidase
753:extracellular exosome
657:exopeptidase activity
7731:Lineweaver–Burk plot
3697:(Neprilysin) at the
2025:renal cell carcinoma
1983:Smooth muscle tumors
1924:basal cell carcinoma
1904:CD10 differentiates
1877:In epithelial tumors
1774:sacubitril/valsartan
1756:Sacubitril/valsartan
1559:mantle cell lymphoma
904:placenta development
376:3 E1|3 29.97 cM
337:Chromosome 3 (mouse)
235:Chromosome 3 (human)
80:List of PDB id codes
53:Available structures
7886:Alzheimer's disease
3540:10.5858/133.12.1965
3166:Am. J. Surg. Pathol
3026:Am. J. Surg. Pathol
2461:Acta Crystallogr. D
1844:Follicular lymphoma
1547:hairy cell leukemia
1505:. Synthesized as a
1503:Alzheimer's disease
1497:and aggregation in
813:cytoplasmic vesicle
803:trans-Golgi network
712:cardiolipin binding
7690:Enzyme superfamily
7623:Enzyme promiscuity
3710:, which is in the
1908:(CD10/CK20+) from
1664:and some advanced
1612:
1598:Signaling peptides
1580:rate-limiting step
1074:ENSMUSG00000027820
914:learning or memory
859:kidney development
837:Biological process
818:neuronal cell body
721:Cellular component
677:peptidase activity
662:hydrolase activity
640:Molecular function
526:epithelium of lens
7846:
7845:
7555:
7554:
7160:
7159:
7156:
7155:
7127:
7126:
7080:General histology
7075:
7074:
6906:Alpha-fetoprotein
6893:Testicular cancer
6818:Alpha-fetoprotein
6753:
6752:
6741:Alpha-fetoprotein
6695:Pancreatic cancer
6667:Colorectal cancer
6654:
6653:
6585:
6584:
6511:
6510:
6503:Homovanillic acid
6403:
6402:
6315:
6314:
6293:
6292:
6273:All (pan-myeloid)
6268:
6267:
6139:
6138:
6119:
6118:
5873:
5872:
3836:
3835:
2269:10.1002/jnr.21074
1955:Urothelial tumors
1894:Pancreatic tumors
1885:(Clear cell RCC)
1361:
1360:
1357:
1356:
1330:
1329:
1295:
1294:
1262:
1261:
1212:
1211:
1179:
1178:
1129:
1128:
1110:
1109:
1080:
1079:
1061:
1060:
1035:
1034:
1016:
1015:
964:
963:
672:metal ion binding
624:
623:
620:
619:
582:
581:
569:
568:
507:
506:
405:
404:
304:
303:
131:
130:
127:
126:
63:Ortholog search:
16:(Redirected from
7903:
7863:
7862:
7854:
7726:Hanes–Woolf plot
7669:Enzyme activator
7664:Enzyme inhibitor
7638:Enzyme catalysis
7582:
7575:
7568:
7559:
7222:Alpha secretases
7187:
7180:
7173:
7164:
7140:Rhabdomyosarcoma
7136:
7084:
6766:
6663:
6596:
6520:
6449:Pheochromocytoma
6412:
6360:
6342:
6335:
6328:
6319:
6207:
6150:
6004:
5921:
5900:
5893:
5886:
5877:
3863:
3856:
3849:
3840:
3822:
3807:
3792:
3777:
3762:
3742:
3735:
3728:
3719:
3652:
3651:
3641:
3631:
3607:
3601:
3600:
3582:
3558:
3552:
3551:
3523:
3517:
3516:
3506:
3482:
3476:
3475:
3457:
3433:
3427:
3426:
3408:
3384:
3375:
3374:
3364:
3354:
3330:
3324:
3323:
3313:
3289:
3283:
3282:
3272:
3248:
3242:
3241:
3210:Int. J. Dermatol
3204:
3198:
3197:
3160:
3151:
3150:
3113:
3107:
3106:
3088:
3064:
3058:
3057:
3021:
3015:
3014:
2985:
2979:
2978:
2960:
2936:
2930:
2929:
2893:
2887:
2886:
2876:
2852:
2846:
2845:
2835:
2803:
2797:
2796:
2778:
2754:
2748:
2747:
2737:
2703:
2697:
2696:
2679:(9): 1389–1409.
2668:
2662:
2661:
2643:
2626:(11): 993–1004.
2611:
2602:
2601:
2573:
2567:
2566:
2542:
2536:
2535:
2525:
2515:
2491:
2485:
2484:
2456:
2447:
2446:
2444:
2418:
2409:
2408:
2380:
2374:
2373:
2363:
2339:
2333:
2332:
2295:
2289:
2288:
2257:J. Neurosci. Res
2251:
2245:
2244:
2234:
2210:
2204:
2203:
2191:
2185:
2184:
2174:
2150:
2144:
2143:
2136:
2127:
2126:
2115:
2109:
2108:
2097:
2091:
2081:
2070:
2060:
2021:Hemangioblastoma
2017:are mostly CD10.
2011:Vascular tumors
1981:(ESS) are CD10 (
1945:and sarcomatoid
1918:Cutaneous tumors
1806:safety concerns.
1726:antihypertensive
1628:antihypertensive
1535:Burkitt lymphoma
1527:germinal centers
1413:; also known as
1412:
1411:
1408:
1407:
1404:
1401:
1398:
1395:
1392:
1389:
1386:
1383:
1380:
1377:
1374:
1343:
1342:
1314:
1307:
1290:
1266:
1257:
1221:
1217:RefSeq (protein)
1207:
1183:
1174:
1138:
1114:
1091:
1065:
1046:
1020:
1001:
970:
919:lung development
763:synaptic vesicle
652:zinc ion binding
630:
616:
607:
600:
593:
578:
546:lobe of prostate
518:
516:Top expressed in
511:
456:
454:Top expressed in
449:
428:
411:
401:
388:
377:
362:
355:
349:
338:
326:
310:
300:
287:
276:
261:
254:
248:
237:
223:
207:
201:
152:
145:
122:
77:
71:
50:
49:
44:
32:
21:
7911:
7910:
7906:
7905:
7904:
7902:
7901:
7900:
7871:
7870:
7869:
7857:
7849:
7847:
7842:
7754:Oxidoreductases
7740:
7716:Enzyme kinetics
7704:
7700:List of enzymes
7673:
7642:
7613:Catalytic triad
7591:
7586:
7556:
7551:
7500:
7353:
7208:
7191:
7161:
7152:
7132:Musculoskeletal
7123:
7100:
7071:
7052:erbB-3 receptor
7047:erbB-2 receptor
7028:
7019:erbB-3 receptor
7005:
6993:Germ cell tumor
6987:
6953:erbB-3 receptor
6930:Prostate cancer
6924:
6887:
6826:Choriocarcinoma
6761:
6759:
6749:
6727:
6689:
6650:
6633:Hemangiosarcoma
6627:
6591:
6590:Cardiovascular/
6581:
6554:
6536:
6507:
6489:
6466:
6457:Normetanephrine
6443:
6399:
6376:
6351:
6346:
6316:
6311:
6289:
6264:
6241:
6196:
6157:
6135:
6115:
6099:
6071:
5995:
5910:
5904:
5874:
5869:
5673:
5467:
5216:
4900:
4623:
4283:
3881:
3867:
3837:
3832:
3829:
3823:
3814:
3808:
3799:
3793:
3784:
3778:
3769:
3763:
3749:
3746:
3660:
3655:
3609:
3608:
3604:
3560:
3559:
3555:
3525:
3524:
3520:
3497:(16): 3706–12.
3484:
3483:
3479:
3435:
3434:
3430:
3386:
3385:
3378:
3332:
3331:
3327:
3291:
3290:
3286:
3250:
3249:
3245:
3206:
3205:
3201:
3172:(10): 1361–71.
3162:
3161:
3154:
3115:
3114:
3110:
3066:
3065:
3061:
3023:
3022:
3018:
2987:
2986:
2982:
2951:(7): 993–1003.
2938:
2937:
2933:
2895:
2894:
2890:
2854:
2853:
2849:
2812:J. Hematopathol
2805:
2804:
2800:
2756:
2755:
2751:
2705:
2704:
2700:
2670:
2669:
2665:
2613:
2612:
2605:
2575:
2574:
2570:
2544:
2543:
2539:
2493:
2492:
2488:
2467:(Pt 2): 392–6.
2458:
2457:
2450:
2420:
2419:
2412:
2382:
2381:
2377:
2348:Pharmacol. Ther
2341:
2340:
2336:
2297:
2296:
2292:
2253:
2252:
2248:
2212:
2211:
2207:
2193:
2192:
2188:
2152:
2151:
2147:
2138:
2137:
2130:
2117:
2116:
2112:
2099:
2098:
2094:
2082:
2073:
2061:
2052:
2048:
2036:
1969:
1967:In other tumors
1879:
1834:
1826:
1824:Immunochemistry
1718:
1600:
1584:peptide hormone
1571:
1511:Golgi apparatus
1459:metalloprotease
1371:
1367:
1352:View/Edit Mouse
1347:View/Edit Human
1310:
1303:
1300:Location (UCSC)
1286:
1282:
1278:
1274:
1253:
1249:
1243:
1239:
1235:
1231:
1227:
1203:
1199:
1195:
1191:
1170:
1166:
1160:
1156:
1152:
1148:
1144:
1102:
1055:ENSG00000196549
948:
832:
768:plasma membrane
716:
682:peptide binding
647:protein binding
612:
602:
601:
574:
565:
560:
556:
552:
548:
544:
540:
536:
532:
528:
514:
503:
498:
496:mucosa of ileum
494:
490:
486:
482:
478:
474:
470:
466:
452:
396:
383:
375:
365:
364:
363:
356:
336:
313:Gene location (
295:
282:
274:
264:
263:
262:
255:
233:
210:Gene location (
199:MME - orthologs
161:
148:
141:
86:
64:
28:
23:
22:
15:
12:
11:
5:
7909:
7907:
7899:
7898:
7893:
7888:
7883:
7873:
7872:
7868:
7867:
7844:
7843:
7841:
7840:
7827:
7814:
7801:
7788:
7775:
7762:
7748:
7746:
7742:
7741:
7739:
7738:
7733:
7728:
7723:
7718:
7712:
7710:
7706:
7705:
7703:
7702:
7697:
7692:
7687:
7681:
7679:
7678:Classification
7675:
7674:
7672:
7671:
7666:
7661:
7656:
7650:
7648:
7644:
7643:
7641:
7640:
7635:
7630:
7625:
7620:
7615:
7610:
7605:
7599:
7597:
7593:
7592:
7587:
7585:
7584:
7577:
7570:
7562:
7553:
7552:
7550:
7549:
7544:
7539:
7534:
7529:
7524:
7519:
7514:
7508:
7506:
7502:
7501:
7499:
7498:
7493:
7488:
7483:
7478:
7473:
7468:
7463:
7458:
7453:
7448:
7443:
7438:
7433:
7428:
7423:
7418:
7413:
7408:
7403:
7398:
7397:
7396:
7391:
7381:
7380:
7379:
7374:
7363:
7361:
7355:
7354:
7352:
7351:
7346:
7341:
7336:
7331:
7326:
7321:
7316:
7311:
7306:
7301:
7296:
7291:
7286:
7281:
7276:
7271:
7266:
7261:
7256:
7251:
7246:
7245:
7244:
7239:
7234:
7229:
7218:
7216:
7210:
7209:
7192:
7190:
7189:
7182:
7175:
7167:
7158:
7157:
7154:
7153:
7151:
7150:
7144:
7142:
7133:
7129:
7128:
7125:
7124:
7122:
7121:
7115:
7113:
7102:
7101:
7099:
7098:
7092:
7090:
7081:
7077:
7076:
7073:
7072:
7070:
7069:
7064:
7059:
7054:
7049:
7044:
7038:
7036:
7030:
7029:
7027:
7026:
7021:
7015:
7013:
7011:Bladder cancer
7007:
7006:
7004:
7003:
6997:
6995:
6989:
6988:
6986:
6985:
6980:
6975:
6970:
6965:
6960:
6955:
6950:
6945:
6940:
6934:
6932:
6926:
6925:
6923:
6922:
6917:
6912:
6903:
6897:
6895:
6889:
6888:
6886:
6885:
6878:
6877:
6876:
6864:
6863:
6862:
6850:
6849:
6848:
6836:
6835:
6834:
6822:
6821:
6820:
6808:
6807:
6806:
6801:
6789:
6788:
6787:
6774:
6772:
6763:
6755:
6754:
6751:
6750:
6748:
6747:
6737:
6735:
6729:
6728:
6726:
6725:
6720:
6715:
6710:
6705:
6699:
6697:
6691:
6690:
6688:
6687:
6682:
6677:
6671:
6669:
6660:
6656:
6655:
6652:
6651:
6649:
6648:
6642:
6640:
6629:
6628:
6626:
6625:
6620:
6615:
6610:
6604:
6602:
6593:
6587:
6586:
6583:
6582:
6580:
6579:
6574:
6568:
6566:
6556:
6555:
6553:
6552:
6546:
6544:
6538:
6537:
6535:
6534:
6528:
6526:
6517:
6516:Nervous system
6513:
6512:
6509:
6508:
6506:
6505:
6499:
6497:
6491:
6490:
6488:
6487:
6485:Chromogranin A
6482:
6476:
6474:
6468:
6467:
6465:
6464:
6459:
6453:
6451:
6445:
6444:
6442:
6441:
6435:
6426:
6420:
6418:
6416:Thyroid cancer
6409:
6405:
6404:
6401:
6400:
6398:
6397:
6392:
6386:
6384:
6378:
6377:
6375:
6374:
6368:
6366:
6357:
6353:
6352:
6347:
6345:
6344:
6337:
6330:
6322:
6313:
6312:
6310:
6309:
6303:
6301:
6295:
6294:
6291:
6290:
6288:
6287:
6282:
6276:
6274:
6270:
6269:
6266:
6265:
6263:
6262:
6257:
6251:
6249:
6243:
6242:
6240:
6239:
6230:
6225:
6215:
6213:
6204:
6198:
6197:
6195:
6194:
6189:
6184:
6179:
6174:
6169:
6163:
6161:
6147:
6141:
6140:
6137:
6136:
6134:
6133:
6127:
6125:
6121:
6120:
6117:
6116:
6114:
6113:
6107:
6105:
6101:
6100:
6098:
6097:
6092:
6087:
6081:
6079:
6073:
6072:
6070:
6069:
6064:
6059:
6054:
6049:
6044:
6039:
6034:
6028:
6027:
6022:
6016:Pan-T antigens
6012:
6010:
6001:
5997:
5996:
5994:
5993:
5988:
5978:
5977:
5972:
5967:
5962:
5957:
5952:
5945:
5944:
5939:
5929:
5927:
5918:
5912:
5911:
5905:
5903:
5902:
5895:
5888:
5880:
5871:
5870:
5868:
5867:
5862:
5857:
5852:
5847:
5842:
5837:
5832:
5827:
5822:
5817:
5812:
5807:
5802:
5797:
5792:
5787:
5782:
5777:
5772:
5767:
5762:
5757:
5752:
5747:
5742:
5737:
5732:
5727:
5722:
5717:
5712:
5707:
5702:
5697:
5692:
5687:
5681:
5679:
5675:
5674:
5672:
5671:
5666:
5661:
5656:
5651:
5646:
5641:
5636:
5631:
5626:
5621:
5616:
5611:
5606:
5601:
5596:
5591:
5586:
5581:
5576:
5571:
5566:
5561:
5556:
5551:
5546:
5541:
5536:
5531:
5526:
5521:
5516:
5511:
5506:
5501:
5496:
5491:
5486:
5481:
5475:
5473:
5469:
5468:
5466:
5465:
5460:
5451:
5446:
5441:
5436:
5431:
5426:
5421:
5416:
5411:
5406:
5405:
5404:
5399:
5389:
5384:
5379:
5374:
5369:
5364:
5359:
5354:
5349:
5344:
5339:
5334:
5329:
5324:
5318:
5309:
5304:
5303:
5302:
5297:
5287:
5282:
5281:
5280:
5275:
5265:
5260:
5255:
5250:
5245:
5240:
5235:
5230:
5224:
5222:
5218:
5217:
5215:
5214:
5209:
5204:
5199:
5194:
5189:
5184:
5179:
5174:
5169:
5164:
5159:
5154:
5149:
5144:
5139:
5134:
5129:
5128:
5127:
5122:
5112:
5107:
5102:
5097:
5096:
5095:
5090:
5085:
5075:
5070:
5065:
5060:
5055:
5054:
5053:
5048:
5038:
5033:
5028:
5023:
5018:
5013:
5008:
5007:
5006:
5001:
4991:
4985:
4980:
4975:
4970:
4961:
4956:
4955:
4954:
4949:
4944:
4934:
4929:
4924:
4919:
4914:
4908:
4906:
4902:
4901:
4899:
4898:
4893:
4888:
4883:
4878:
4873:
4868:
4863:
4858:
4853:
4848:
4843:
4838:
4833:
4828:
4823:
4818:
4813:
4808:
4803:
4798:
4793:
4788:
4783:
4778:
4773:
4772:
4771:
4766:
4756:
4755:
4754:
4749:
4739:
4734:
4729:
4724:
4719:
4714:
4709:
4704:
4699:
4694:
4689:
4684:
4679:
4678:
4677:
4672:
4662:
4657:
4652:
4647:
4642:
4637:
4631:
4629:
4625:
4624:
4622:
4621:
4616:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4572:
4567:
4562:
4557:
4552:
4547:
4546:
4545:
4540:
4535:
4530:
4525:
4520:
4510:
4505:
4500:
4495:
4490:
4485:
4484:
4483:
4478:
4468:
4463:
4458:
4453:
4448:
4443:
4438:
4433:
4428:
4427:
4426:
4421:
4416:
4411:
4406:
4401:
4391:
4390:
4389:
4384:
4379:
4369:
4364:
4363:
4362:
4357:
4352:
4342:
4337:
4332:
4327:
4322:
4317:
4312:
4307:
4302:
4297:
4291:
4289:
4285:
4284:
4282:
4281:
4276:
4275:
4274:
4269:
4264:
4259:
4254:
4249:
4239:
4234:
4229:
4224:
4219:
4214:
4209:
4208:
4207:
4202:
4197:
4192:
4182:
4177:
4172:
4167:
4162:
4157:
4152:
4147:
4142:
4137:
4136:
4135:
4130:
4120:
4115:
4110:
4105:
4100:
4095:
4090:
4085:
4080:
4075:
4070:
4065:
4060:
4055:
4050:
4049:
4048:
4043:
4033:
4028:
4023:
4018:
4017:
4016:
4011:
4006:
4001:
3991:
3986:
3981:
3980:
3979:
3969:
3964:
3959:
3954:
3949:
3948:
3947:
3942:
3937:
3927:
3922:
3921:
3920:
3915:
3910:
3905:
3900:
3889:
3887:
3883:
3882:
3868:
3866:
3865:
3858:
3851:
3843:
3834:
3833:
3831:
3830:
3824:
3817:
3815:
3809:
3802:
3800:
3794:
3787:
3785:
3779:
3772:
3770:
3764:
3757:
3754:
3751:
3750:
3747:
3745:
3744:
3737:
3730:
3722:
3703:
3702:
3681:
3671:
3659:
3658:External links
3656:
3654:
3653:
3602:
3553:
3534:(12): 1965–8.
3518:
3491:J. Clin. Oncol
3477:
3442:Histopathology
3428:
3376:
3325:
3284:
3257:Iran J Med Sci
3243:
3199:
3152:
3108:
3059:
3016:
2980:
2931:
2888:
2847:
2798:
2769:(8): 1113–20.
2749:
2698:
2663:
2603:
2568:
2537:
2486:
2448:
2435:(4): 707–730.
2410:
2375:
2334:
2290:
2246:
2205:
2186:
2165:(4): 459–473.
2145:
2128:
2110:
2092:
2071:
2049:
2047:
2044:
2043:
2042:
2035:
2032:
2031:
2030:
2029:
2028:
2018:
2009:
2008:
2007:
2002:
1997:
1992:
1986:
1976:
1968:
1965:
1964:
1963:
1962:
1961:
1952:
1951:
1950:
1935:
1928:trichoblastoma
1915:
1914:
1913:
1902:
1891:
1890:
1889:
1878:
1875:
1874:
1873:
1872:
1871:
1862:
1861:
1860:
1850:
1847:
1841:
1833:
1830:
1825:
1822:
1818:
1817:
1812:
1807:
1793:
1788:
1782:
1776:
1763:
1717:
1714:
1599:
1596:
1570:
1567:
1359:
1358:
1355:
1354:
1349:
1339:
1338:
1332:
1331:
1328:
1327:
1325:
1323:
1316:
1315:
1308:
1301:
1297:
1296:
1293:
1292:
1270:
1269:
1263:
1260:
1259:
1245:
1244:
1218:
1214:
1213:
1210:
1209:
1187:
1186:
1180:
1177:
1176:
1162:
1161:
1135:
1131:
1130:
1127:
1126:
1118:
1117:
1111:
1108:
1107:
1095:
1094:
1088:
1082:
1081:
1078:
1077:
1069:
1068:
1062:
1059:
1058:
1050:
1049:
1043:
1037:
1036:
1033:
1032:
1024:
1023:
1017:
1014:
1013:
1005:
1004:
998:
992:
991:
986:
981:
977:
976:
966:
965:
962:
961:
950:
949:
947:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
840:
838:
834:
833:
831:
830:
825:
820:
815:
810:
805:
800:
798:early endosome
795:
790:
785:
780:
775:
770:
765:
760:
755:
750:
745:
740:
735:
733:focal adhesion
730:
724:
722:
718:
717:
715:
714:
709:
704:
699:
694:
689:
684:
679:
674:
669:
664:
659:
654:
649:
643:
641:
637:
636:
626:
625:
622:
621:
618:
617:
609:
608:
590:
584:
583:
580:
579:
571:
570:
567:
566:
564:
563:
559:
555:
551:
547:
543:
539:
535:
531:
527:
523:
520:
519:
508:
505:
504:
502:
501:
497:
493:
489:
485:
481:
477:
473:
469:
465:
464:jejunal mucosa
461:
458:
457:
445:
444:
436:
425:
419:
418:
415:RNA expression
407:
406:
403:
402:
394:
390:
389:
381:
378:
373:
367:
366:
357:
350:
344:
340:
339:
334:
328:
327:
319:
318:
306:
305:
302:
301:
293:
289:
288:
280:
277:
272:
266:
265:
256:
249:
243:
239:
238:
231:
225:
224:
216:
215:
203:
202:
159:
155:
154:
146:
138:
137:
133:
132:
129:
128:
125:
124:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
7908:
7897:
7896:Tumor markers
7894:
7892:
7889:
7887:
7884:
7882:
7879:
7878:
7876:
7866:
7861:
7856:
7852:
7838:
7834:
7833:
7828:
7825:
7821:
7820:
7815:
7812:
7808:
7807:
7802:
7799:
7795:
7794:
7789:
7786:
7782:
7781:
7776:
7773:
7769:
7768:
7763:
7760:
7756:
7755:
7750:
7749:
7747:
7743:
7737:
7734:
7732:
7729:
7727:
7724:
7722:
7719:
7717:
7714:
7713:
7711:
7707:
7701:
7698:
7696:
7695:Enzyme family
7693:
7691:
7688:
7686:
7683:
7682:
7680:
7676:
7670:
7667:
7665:
7662:
7660:
7659:Cooperativity
7657:
7655:
7652:
7651:
7649:
7645:
7639:
7636:
7634:
7631:
7629:
7626:
7624:
7621:
7619:
7618:Oxyanion hole
7616:
7614:
7611:
7609:
7606:
7604:
7601:
7600:
7598:
7594:
7590:
7583:
7578:
7576:
7571:
7569:
7564:
7563:
7560:
7548:
7545:
7543:
7540:
7538:
7535:
7533:
7530:
7528:
7525:
7523:
7520:
7518:
7515:
7513:
7510:
7509:
7507:
7503:
7497:
7494:
7492:
7489:
7487:
7484:
7482:
7479:
7477:
7474:
7472:
7469:
7467:
7464:
7462:
7459:
7457:
7454:
7452:
7449:
7447:
7444:
7442:
7439:
7437:
7434:
7432:
7429:
7427:
7424:
7422:
7419:
7417:
7414:
7412:
7409:
7407:
7404:
7402:
7399:
7395:
7392:
7390:
7387:
7386:
7385:
7382:
7378:
7375:
7373:
7370:
7369:
7368:
7365:
7364:
7362:
7360:
7356:
7350:
7347:
7345:
7342:
7340:
7337:
7335:
7332:
7330:
7327:
7325:
7322:
7320:
7317:
7315:
7312:
7310:
7307:
7305:
7302:
7300:
7297:
7295:
7292:
7290:
7287:
7285:
7282:
7280:
7277:
7275:
7272:
7270:
7267:
7265:
7262:
7260:
7257:
7255:
7252:
7250:
7247:
7243:
7240:
7238:
7235:
7233:
7230:
7228:
7225:
7224:
7223:
7220:
7219:
7217:
7215:
7214:ADAM proteins
7211:
7206:
7203:
7199:
7195:
7188:
7183:
7181:
7176:
7174:
7169:
7168:
7165:
7149:
7146:
7145:
7143:
7141:
7137:
7134:
7130:
7120:
7117:
7116:
7114:
7111:
7107:
7103:
7097:
7094:
7093:
7091:
7089:
7085:
7082:
7078:
7068:
7065:
7063:
7060:
7058:
7055:
7053:
7050:
7048:
7045:
7043:
7040:
7039:
7037:
7035:
7034:Breast cancer
7031:
7025:
7022:
7020:
7017:
7016:
7014:
7012:
7008:
7002:
6999:
6998:
6996:
6994:
6990:
6984:
6981:
6979:
6976:
6974:
6971:
6969:
6966:
6964:
6961:
6959:
6956:
6954:
6951:
6949:
6946:
6944:
6941:
6939:
6936:
6935:
6933:
6931:
6927:
6921:
6918:
6916:
6913:
6911:
6907:
6904:
6902:
6899:
6898:
6896:
6894:
6890:
6884:
6883:
6879:
6875:
6872:
6871:
6870:
6869:
6865:
6861:
6858:
6857:
6856:
6855:
6851:
6847:
6844:
6843:
6842:
6841:
6837:
6833:
6830:
6829:
6828:
6827:
6823:
6819:
6816:
6815:
6814:
6813:
6809:
6805:
6802:
6800:
6797:
6796:
6795:
6794:
6790:
6786:
6783:
6782:
6781:
6780:
6776:
6775:
6773:
6771:
6770:Ovarian tumor
6767:
6764:
6758:Reproductive/
6756:
6746:
6742:
6739:
6738:
6736:
6734:
6730:
6724:
6721:
6719:
6716:
6714:
6711:
6709:
6706:
6704:
6701:
6700:
6698:
6696:
6692:
6686:
6683:
6681:
6678:
6676:
6673:
6672:
6670:
6668:
6664:
6661:
6657:
6647:
6644:
6643:
6641:
6638:
6634:
6630:
6624:
6621:
6619:
6616:
6614:
6611:
6609:
6606:
6605:
6603:
6601:
6597:
6594:
6588:
6578:
6575:
6573:
6570:
6569:
6567:
6565:
6561:
6557:
6551:
6548:
6547:
6545:
6543:
6539:
6533:
6530:
6529:
6527:
6525:
6521:
6518:
6514:
6504:
6501:
6500:
6498:
6496:
6495:Neuroblastoma
6492:
6486:
6483:
6481:
6480:Synaptophysin
6478:
6477:
6475:
6473:
6469:
6463:
6460:
6458:
6455:
6454:
6452:
6450:
6446:
6439:
6436:
6434:
6430:
6427:
6425:
6424:Thyroglobulin
6422:
6421:
6419:
6417:
6413:
6410:
6406:
6396:
6393:
6391:
6388:
6387:
6385:
6383:
6382:Lymphosarcoma
6379:
6373:
6370:
6369:
6367:
6365:
6361:
6358:
6354:
6350:
6349:Tumor markers
6343:
6338:
6336:
6331:
6329:
6324:
6323:
6320:
6308:
6305:
6304:
6302:
6300:
6296:
6286:
6283:
6281:
6278:
6277:
6275:
6271:
6261:
6258:
6256:
6253:
6252:
6250:
6248:
6244:
6238:
6234:
6231:
6229:
6226:
6224:
6220:
6217:
6216:
6214:
6212:
6208:
6205:
6203:
6199:
6193:
6190:
6188:
6185:
6183:
6180:
6178:
6175:
6173:
6170:
6168:
6165:
6164:
6162:
6160:
6159:Myelomonocyte
6155:
6151:
6148:
6146:
6142:
6132:
6129:
6128:
6126:
6122:
6112:
6109:
6108:
6106:
6102:
6096:
6093:
6091:
6088:
6086:
6083:
6082:
6080:
6078:
6074:
6068:
6065:
6063:
6060:
6058:
6055:
6053:
6050:
6048:
6045:
6043:
6040:
6038:
6035:
6033:
6030:
6029:
6026:
6023:
6021:
6017:
6014:
6013:
6011:
6009:
6005:
6002:
5998:
5992:
5989:
5987:
5983:
5980:
5979:
5976:
5973:
5971:
5968:
5966:
5963:
5961:
5958:
5956:
5953:
5951:
5947:
5946:
5943:
5940:
5938:
5934:
5931:
5930:
5928:
5926:
5922:
5919:
5917:
5913:
5908:
5901:
5896:
5894:
5889:
5887:
5882:
5881:
5878:
5866:
5863:
5861:
5858:
5856:
5853:
5851:
5848:
5846:
5843:
5841:
5838:
5836:
5833:
5831:
5828:
5826:
5823:
5821:
5818:
5816:
5813:
5811:
5808:
5806:
5803:
5801:
5798:
5796:
5793:
5791:
5788:
5786:
5783:
5781:
5778:
5776:
5773:
5771:
5768:
5766:
5763:
5761:
5758:
5756:
5753:
5751:
5748:
5746:
5743:
5741:
5738:
5736:
5733:
5731:
5728:
5726:
5723:
5721:
5718:
5716:
5713:
5711:
5708:
5706:
5703:
5701:
5698:
5696:
5693:
5691:
5688:
5686:
5683:
5682:
5680:
5676:
5670:
5667:
5665:
5662:
5660:
5657:
5655:
5652:
5650:
5647:
5645:
5642:
5640:
5637:
5635:
5632:
5630:
5627:
5625:
5622:
5620:
5617:
5615:
5612:
5610:
5607:
5605:
5602:
5600:
5597:
5595:
5592:
5590:
5587:
5585:
5582:
5580:
5577:
5575:
5572:
5570:
5567:
5565:
5562:
5560:
5557:
5555:
5552:
5550:
5547:
5545:
5542:
5540:
5537:
5535:
5532:
5530:
5527:
5525:
5522:
5520:
5517:
5515:
5512:
5510:
5507:
5505:
5502:
5500:
5497:
5495:
5492:
5490:
5487:
5485:
5482:
5480:
5477:
5476:
5474:
5470:
5464:
5461:
5459:
5455:
5452:
5450:
5447:
5445:
5442:
5440:
5437:
5435:
5432:
5430:
5427:
5425:
5422:
5420:
5417:
5415:
5412:
5410:
5407:
5403:
5400:
5398:
5395:
5394:
5393:
5390:
5388:
5385:
5383:
5380:
5378:
5375:
5373:
5370:
5368:
5365:
5363:
5360:
5358:
5355:
5353:
5350:
5348:
5345:
5343:
5340:
5338:
5335:
5333:
5330:
5328:
5325:
5322:
5319:
5317:
5313:
5310:
5308:
5305:
5301:
5298:
5296:
5293:
5292:
5291:
5288:
5286:
5283:
5279:
5276:
5274:
5271:
5270:
5269:
5266:
5264:
5261:
5259:
5256:
5254:
5251:
5249:
5246:
5244:
5241:
5239:
5236:
5234:
5231:
5229:
5226:
5225:
5223:
5219:
5213:
5210:
5208:
5205:
5203:
5200:
5198:
5195:
5193:
5190:
5188:
5185:
5183:
5180:
5178:
5175:
5173:
5170:
5168:
5165:
5163:
5160:
5158:
5155:
5153:
5150:
5148:
5145:
5143:
5140:
5138:
5135:
5133:
5130:
5126:
5123:
5121:
5118:
5117:
5116:
5113:
5111:
5108:
5106:
5103:
5101:
5098:
5094:
5091:
5089:
5086:
5084:
5081:
5080:
5079:
5076:
5074:
5071:
5069:
5066:
5064:
5061:
5059:
5056:
5052:
5049:
5047:
5044:
5043:
5042:
5039:
5037:
5034:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5014:
5012:
5009:
5005:
5002:
5000:
4997:
4996:
4995:
4992:
4989:
4986:
4984:
4981:
4979:
4976:
4974:
4971:
4969:
4965:
4962:
4960:
4957:
4953:
4950:
4948:
4945:
4943:
4940:
4939:
4938:
4935:
4933:
4930:
4928:
4925:
4923:
4920:
4918:
4915:
4913:
4910:
4909:
4907:
4903:
4897:
4894:
4892:
4889:
4887:
4884:
4882:
4879:
4877:
4874:
4872:
4869:
4867:
4864:
4862:
4859:
4857:
4854:
4852:
4849:
4847:
4844:
4842:
4839:
4837:
4834:
4832:
4829:
4827:
4824:
4822:
4819:
4817:
4814:
4812:
4809:
4807:
4804:
4802:
4799:
4797:
4794:
4792:
4789:
4787:
4784:
4782:
4779:
4777:
4774:
4770:
4767:
4765:
4762:
4761:
4760:
4757:
4753:
4750:
4748:
4745:
4744:
4743:
4740:
4738:
4735:
4733:
4730:
4728:
4725:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4695:
4693:
4690:
4688:
4685:
4683:
4680:
4676:
4673:
4671:
4668:
4667:
4666:
4663:
4661:
4658:
4656:
4653:
4651:
4648:
4646:
4643:
4641:
4638:
4636:
4633:
4632:
4630:
4626:
4620:
4617:
4615:
4612:
4610:
4607:
4605:
4602:
4600:
4597:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4576:
4573:
4571:
4568:
4566:
4563:
4561:
4558:
4556:
4553:
4551:
4548:
4544:
4541:
4539:
4536:
4534:
4531:
4529:
4526:
4524:
4521:
4519:
4516:
4515:
4514:
4511:
4509:
4506:
4504:
4501:
4499:
4496:
4494:
4491:
4489:
4486:
4482:
4479:
4477:
4474:
4473:
4472:
4469:
4467:
4464:
4462:
4459:
4457:
4454:
4452:
4449:
4447:
4444:
4442:
4439:
4437:
4434:
4432:
4429:
4425:
4422:
4420:
4417:
4415:
4412:
4410:
4407:
4405:
4402:
4400:
4397:
4396:
4395:
4392:
4388:
4385:
4383:
4380:
4378:
4375:
4374:
4373:
4370:
4368:
4365:
4361:
4358:
4356:
4353:
4351:
4348:
4347:
4346:
4343:
4341:
4338:
4336:
4333:
4331:
4328:
4326:
4323:
4321:
4318:
4316:
4313:
4311:
4308:
4306:
4303:
4301:
4298:
4296:
4293:
4292:
4290:
4286:
4280:
4277:
4273:
4270:
4268:
4265:
4263:
4260:
4258:
4255:
4253:
4250:
4248:
4245:
4244:
4243:
4240:
4238:
4235:
4233:
4230:
4228:
4225:
4223:
4220:
4218:
4215:
4213:
4210:
4206:
4203:
4201:
4198:
4196:
4193:
4191:
4188:
4187:
4186:
4183:
4181:
4178:
4176:
4173:
4171:
4168:
4166:
4163:
4161:
4158:
4156:
4153:
4151:
4148:
4146:
4143:
4141:
4138:
4134:
4131:
4129:
4126:
4125:
4124:
4121:
4119:
4116:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4064:
4061:
4059:
4056:
4054:
4051:
4047:
4044:
4042:
4039:
4038:
4037:
4034:
4032:
4029:
4027:
4024:
4022:
4019:
4015:
4012:
4010:
4007:
4005:
4002:
4000:
3997:
3996:
3995:
3992:
3990:
3987:
3985:
3982:
3978:
3975:
3974:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3946:
3943:
3941:
3938:
3936:
3933:
3932:
3931:
3928:
3926:
3923:
3919:
3916:
3914:
3911:
3909:
3906:
3904:
3901:
3899:
3896:
3895:
3894:
3891:
3890:
3888:
3884:
3879:
3875:
3871:
3864:
3859:
3857:
3852:
3850:
3845:
3844:
3841:
3827:
3821:
3816:
3812:
3806:
3801:
3797:
3791:
3786:
3782:
3776:
3771:
3767:
3761:
3756:
3752:
3743:
3738:
3736:
3731:
3729:
3724:
3723:
3720:
3716:
3715:
3713:
3712:public domain
3709:
3700:
3696:
3695:
3690:
3686:
3682:
3679:
3675:
3672:
3670:
3666:
3662:
3661:
3657:
3649:
3645:
3640:
3635:
3630:
3625:
3621:
3617:
3616:Diagn. Pathol
3613:
3606:
3603:
3598:
3594:
3590:
3586:
3581:
3576:
3573:(6): 788–94.
3572:
3568:
3564:
3557:
3554:
3549:
3545:
3541:
3537:
3533:
3529:
3522:
3519:
3514:
3510:
3505:
3500:
3496:
3492:
3488:
3481:
3478:
3473:
3469:
3465:
3461:
3456:
3451:
3447:
3443:
3439:
3432:
3429:
3424:
3420:
3416:
3412:
3407:
3402:
3399:(9): 923–30.
3398:
3394:
3390:
3383:
3381:
3377:
3372:
3368:
3363:
3358:
3353:
3348:
3344:
3340:
3339:Diagn. Pathol
3336:
3329:
3326:
3321:
3317:
3312:
3307:
3303:
3299:
3295:
3288:
3285:
3280:
3276:
3271:
3266:
3262:
3258:
3254:
3247:
3244:
3239:
3235:
3231:
3227:
3223:
3219:
3215:
3211:
3203:
3200:
3195:
3191:
3187:
3183:
3179:
3175:
3171:
3167:
3159:
3157:
3153:
3148:
3144:
3140:
3136:
3132:
3128:
3125:(5): 454–61.
3124:
3120:
3112:
3109:
3104:
3100:
3096:
3092:
3087:
3082:
3079:(9): 879–85.
3078:
3074:
3070:
3063:
3060:
3055:
3051:
3047:
3043:
3039:
3035:
3031:
3027:
3020:
3017:
3012:
3008:
3004:
3000:
2997:(7): 784–91.
2996:
2992:
2984:
2981:
2976:
2972:
2968:
2964:
2959:
2954:
2950:
2946:
2942:
2935:
2932:
2927:
2923:
2919:
2915:
2911:
2907:
2904:(6): 545–51.
2903:
2899:
2898:Virchows Arch
2892:
2889:
2884:
2880:
2875:
2870:
2867:(2): 183–90.
2866:
2862:
2858:
2851:
2848:
2843:
2839:
2834:
2829:
2825:
2821:
2818:(4): 187–94.
2817:
2813:
2809:
2802:
2799:
2794:
2790:
2786:
2782:
2777:
2772:
2768:
2764:
2760:
2753:
2750:
2745:
2741:
2736:
2731:
2727:
2723:
2720:(4): 665–70.
2719:
2715:
2714:
2709:
2702:
2699:
2694:
2690:
2686:
2682:
2678:
2674:
2667:
2664:
2659:
2655:
2651:
2647:
2642:
2637:
2633:
2629:
2625:
2621:
2617:
2610:
2608:
2604:
2599:
2595:
2591:
2587:
2583:
2579:
2572:
2569:
2564:
2560:
2556:
2552:
2548:
2541:
2538:
2533:
2529:
2524:
2519:
2514:
2509:
2505:
2501:
2497:
2490:
2487:
2482:
2478:
2474:
2470:
2466:
2462:
2455:
2453:
2449:
2443:
2438:
2434:
2430:
2429:
2424:
2417:
2415:
2411:
2406:
2402:
2398:
2394:
2391:(1): 236–41.
2390:
2386:
2379:
2376:
2371:
2367:
2362:
2357:
2354:(2): 129–48.
2353:
2349:
2345:
2338:
2335:
2330:
2326:
2322:
2318:
2314:
2313:10.1038/72237
2310:
2307:(2): 143–50.
2306:
2302:
2294:
2291:
2286:
2282:
2278:
2274:
2270:
2266:
2263:(8): 1871–8.
2262:
2258:
2250:
2247:
2242:
2238:
2233:
2228:
2224:
2220:
2216:
2209:
2206:
2201:
2197:
2190:
2187:
2182:
2178:
2173:
2168:
2164:
2160:
2156:
2149:
2146:
2141:
2135:
2133:
2129:
2124:
2120:
2114:
2111:
2106:
2102:
2096:
2093:
2089:
2085:
2080:
2078:
2076:
2072:
2068:
2064:
2059:
2057:
2055:
2051:
2045:
2041:
2038:
2037:
2033:
2026:
2022:
2019:
2016:
2013:
2012:
2010:
2006:
2003:
2001:
1998:
1996:
1993:
1990:
1987:
1984:
1980:
1977:
1974:
1973:
1971:
1970:
1966:
1959:
1958:
1956:
1953:
1948:
1944:
1940:
1936:
1933:
1929:
1925:
1921:
1920:
1919:
1916:
1911:
1907:
1903:
1900:
1897:
1896:
1895:
1892:
1887:
1886:
1884:
1881:
1880:
1876:
1869:
1868:
1866:
1863:
1858:
1854:
1853:
1851:
1848:
1845:
1842:
1839:
1836:
1835:
1831:
1829:
1823:
1821:
1816:
1813:
1811:
1808:
1805:
1801:
1797:
1794:
1792:
1789:
1786:
1783:
1780:
1777:
1775:
1771:
1768:(AHU-377), a
1767:
1764:
1761:
1757:
1754:
1753:
1752:
1750:
1749:heart failure
1745:
1743:
1739:
1735:
1731:
1727:
1723:
1715:
1713:
1711:
1709:
1704:
1702:
1697:
1695:
1690:
1688:
1683:
1679:
1675:
1671:
1667:
1663:
1660:
1656:
1652:
1647:
1645:
1641:
1637:
1633:
1629:
1625:
1621:
1617:
1609:
1604:
1597:
1595:
1592:
1588:
1585:
1581:
1576:
1575:knockout mice
1568:
1566:
1564:
1560:
1556:
1552:
1548:
1544:
1540:
1536:
1532:
1528:
1522:
1519:
1514:
1512:
1508:
1504:
1500:
1499:neural tissue
1496:
1492:
1488:
1484:
1480:
1476:
1472:
1468:
1464:
1461:that cleaves
1460:
1456:
1452:
1448:
1444:
1440:
1436:
1432:
1428:
1424:
1420:
1416:
1410:
1365:
1353:
1348:
1344:
1340:
1337:
1333:
1326:
1324:
1321:
1317:
1313:
1309:
1306:
1302:
1298:
1291:
1289:
1285:
1281:
1277:
1271:
1267:
1264:
1258:
1256:
1252:
1246:
1242:
1238:
1234:
1230:
1226:
1222:
1219:
1215:
1208:
1206:
1202:
1198:
1194:
1188:
1184:
1181:
1175:
1173:
1169:
1163:
1159:
1155:
1151:
1147:
1143:
1139:
1136:
1134:RefSeq (mRNA)
1132:
1125:
1124:
1119:
1115:
1112:
1106:
1105:
1101:
1096:
1092:
1089:
1087:
1083:
1076:
1075:
1070:
1066:
1063:
1057:
1056:
1051:
1047:
1044:
1042:
1038:
1031:
1030:
1025:
1021:
1018:
1012:
1011:
1006:
1002:
999:
997:
993:
990:
987:
985:
982:
978:
975:
971:
967:
960:
956:
951:
945:
942:
940:
937:
935:
932:
930:
927:
925:
922:
920:
917:
915:
912:
910:
907:
905:
902:
900:
897:
895:
892:
890:
887:
885:
882:
880:
877:
875:
872:
870:
867:
865:
862:
860:
857:
855:
852:
850:
847:
845:
842:
841:
839:
836:
835:
829:
826:
824:
823:membrane raft
821:
819:
816:
814:
811:
809:
806:
804:
801:
799:
796:
794:
791:
789:
786:
784:
781:
779:
776:
774:
771:
769:
766:
764:
761:
759:
756:
754:
751:
749:
746:
744:
741:
739:
736:
734:
731:
729:
726:
725:
723:
720:
719:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
688:
685:
683:
680:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
644:
642:
639:
638:
635:
634:Gene ontology
631:
627:
615:
610:
606:
599:
594:
591:
589:
585:
577:
572:
561:
557:
553:
549:
545:
542:Gonadal ridge
541:
537:
533:
529:
525:
524:
521:
517:
512:
509:
499:
495:
491:
487:
484:kidney tubule
483:
479:
475:
471:
467:
463:
462:
459:
455:
450:
447:
446:
443:
441:
437:
435:
434:
430:
429:
426:
424:
420:
416:
412:
408:
400:
395:
391:
387:
382:
372:
368:
361:
354:
348:
341:
333:
329:
325:
320:
316:
311:
307:
299:
294:
290:
286:
281:
271:
267:
260:
253:
247:
240:
236:
230:
226:
222:
217:
213:
208:
204:
200:
196:
192:
188:
184:
180:
176:
172:
168:
164:
156:
151:
144:
139:
134:
123:
121:
117:
113:
109:
105:
101:
97:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
30:
19:
7832:Translocases
7829:
7816:
7803:
7790:
7777:
7767:Transferases
7764:
7751:
7608:Binding site
7511:
7367:Collagenases
6880:
6866:
6860:Testosterone
6852:
6840:Dysgerminoma
6838:
6824:
6810:
6791:
6777:
6572:S100 protein
6371:
5936:
5391:
5311:
5289:
5267:
5114:
5077:
5040:
4993:
4963:
4936:
4758:
4664:
4512:
4241:
3993:
3988:
3825:
3810:
3795:
3780:
3765:
3705:
3704:
3692:
3619:
3615:
3605:
3570:
3566:
3556:
3531:
3527:
3521:
3494:
3490:
3480:
3448:(3): 273–8.
3445:
3441:
3431:
3396:
3392:
3342:
3338:
3328:
3304:(3): 371–9.
3301:
3297:
3287:
3263:(2): 100–6.
3260:
3256:
3246:
3216:(7): 713–7.
3213:
3209:
3202:
3169:
3165:
3122:
3118:
3111:
3076:
3072:
3062:
3032:(1): 54–61.
3029:
3025:
3019:
2994:
2990:
2983:
2948:
2944:
2934:
2901:
2897:
2891:
2864:
2860:
2850:
2815:
2811:
2801:
2766:
2762:
2752:
2717:
2711:
2701:
2676:
2672:
2666:
2623:
2619:
2581:
2577:
2571:
2557:(4): 831–9.
2554:
2550:
2540:
2503:
2500:J Transl Med
2499:
2489:
2464:
2460:
2432:
2426:
2388:
2384:
2378:
2351:
2347:
2337:
2304:
2300:
2293:
2260:
2256:
2249:
2222:
2218:
2208:
2199:
2189:
2162:
2158:
2148:
2122:
2113:
2104:
2095:
1827:
1819:
1779:Sacubitrilat
1746:
1719:
1706:
1701:Plectranthus
1699:
1692:
1685:
1670:lung cancers
1648:
1613:
1587:somatostatin
1572:
1523:
1515:
1491:amyloid beta
1450:
1442:
1438:
1434:
1430:
1426:
1422:
1418:
1414:
1363:
1362:
1288:NP_001344264
1280:NP_001276392
1276:NP_001276391
1273:
1255:NP_001341573
1251:NP_001341572
1248:
1241:NP_001341571
1205:NM_001357335
1201:NM_001289463
1197:NM_001289462
1190:
1172:NM_001354644
1168:NM_001354643
1165:
1158:NM_001354642
1121:
1098:
1072:
1053:
1027:
1008:
988:
983:
909:human ageing
808:cell surface
728:brush border
562:vas deferens
492:human kidney
438:
431:
296:155,183,704
283:155,024,124
158:External IDs
85:
29:
7603:Active site
7537:Lysostaphin
7522:Thermolysin
7384:Gelatinases
7119:Cytokeratin
7057:Cathepsin D
6646:Factor VIII
6637:endothelium
6600:Lung cancer
6592:respiratory
6542:Astrocytoma
6524:Brain tumor
5982:plasma cell
5965:CD23/FcεRII
3748:PDB gallery
3567:Mod. Pathol
3393:Mod. Pathol
3073:Mod. Pathol
2991:Hum. Pathol
2945:Mod. Pathol
2763:Mod. Pathol
2641:10993/27659
2584:(1): 86–8.
1815:Candoxatril
1796:Omapatrilat
1734:substance P
1730:enkephalins
1703:cf barbatus
1680:related to
1636:substance P
1632:enkephalins
1479:neurotensin
1475:substance P
1471:enkephalins
1457:-dependent
889:proteolysis
488:sural nerve
397:63,293,451
384:63,148,958
136:Identifiers
7875:Categories
7806:Isomerases
7780:Hydrolases
7647:Regulation
7512:Neprilysin
7110:epithelium
6433:Calcitonin
6372:Neprilysin
5937:CD10/CALLA
5933:Pre-B cell
5909:by lineage
3876:(see also
3674:Neprilysin
2551:Cancer Res
2225:(1): 2–3.
2200:CD Markers
2090:, May 2017
2069:, May 2017
2046:References
1804:angioedema
1791:UK-414,495
1766:Sacubitril
1738:endothelin
1716:Inhibitors
1710:longiflora
1659:metastatic
1640:endothelin
1487:bradykinin
1364:Neprilysin
828:presynapse
468:glomerulus
442:(ortholog)
179:HomoloGene
7891:EC 3.4.24
7685:EC number
7194:Proteases
7106:Carcinoma
6659:Digestive
6613:Enolase 2
6462:Enolase 2
6408:Endocrine
6299:Stem cell
6090:CD56/NCAM
3622:(1): 39.
3345:(1): 38.
3238:205395744
2578:Pharmazie
1901:are CD10.
1810:Ecadotril
1760:enalapril
1722:analgesic
1694:Kniphofia
1687:Ceropegia
1674:autocrine
1666:melanomas
1662:carcinoma
1655:biomarker
1624:analgesic
1591:oxidative
1445:)) is an
1284:NP_032630
1237:NP_009220
1233:NP_009219
1229:NP_009218
1225:NP_000893
1193:NM_008604
1154:NM_007289
1150:NM_007288
1146:NM_007287
1142:NM_000902
974:Orthologs
743:cytoplasm
187:GeneCards
7709:Kinetics
7633:Cofactor
7596:Activity
7547:ZMPSTE24
7349:ADAMTS13
7344:ADAMTS12
7339:ADAMTS10
7096:Vimentin
7062:CA 27-29
6760:urinary/
6564:Melanoma
6364:Lymphoma
5960:CD21/CR2
5948:mature:
5916:Lymphoid
3870:Proteins
3648:22497861
3597:16510470
3589:15578072
3548:19961253
3513:15867200
3472:42287024
3464:11532038
3423:30632093
3415:12218209
3371:19917108
3320:16191505
3279:23825889
3230:19570076
3186:11023097
3139:22417859
3103:21020212
3095:13679451
3054:25639416
3046:14707864
3011:16084948
2975:22353148
2967:21499231
2926:23189608
2918:15517363
2883:11488064
2842:20309427
2785:15920553
2744:22431545
2693:85007768
2650:25176015
2598:18271311
2532:17207277
2506:(1): 2.
2481:14747736
2405:14511676
2370:16112736
2329:22431826
2321:10655101
2301:Nat. Med
2285:46527377
2277:16998901
2241:20051779
2159:Immunity
2086:–
2065:–
2034:See also
2027:is CD10)
1943:melanoma
1689:rupicola
1682:bombesin
1678:homologs
1483:oxytocin
1467:glucagon
1463:peptides
1336:Wikidata
953:Sources:
783:dendrite
748:membrane
558:calvaria
538:prostate
480:duodenum
7865:Biology
7819:Ligases
7589:Enzymes
7334:ADAMTS9
7329:ADAMTS8
7324:ADAMTS5
7319:ADAMTS4
7314:ADAMTS3
7309:ADAMTS2
7304:ADAMTS1
7088:Sarcoma
7042:CA 15-3
6978:TMPRSS2
6874:Inhibin
6211:CFU-Meg
6145:Myeloid
6077:NK cell
5678:301–350
5472:251–300
5424:CD240CE
5221:201–250
4905:151–200
4628:101–150
3699:PDBe-KB
3689:UniProt
3669:M13.001
3639:3364142
3362:2780995
3270:3700055
3194:3211829
3147:1348915
2833:2798934
2793:7563005
2735:4975158
2563:8631021
2523:1770905
2181:7584137
2088:Ensembl
2067:Ensembl
1770:prodrug
1708:Pavetta
1696:sumarae
1495:folding
1086:UniProt
1041:Ensembl
980:Species
959:QuickGO
773:synapse
417:pattern
143:Aliases
7851:Portal
7793:Lyases
7471:MMP23B
7466:MMP23A
7299:ADAM33
7294:ADAM28
7289:ADAM23
7284:ADAM22
7279:ADAM18
7274:ADAM15
7269:ADAM12
7264:ADAM11
7242:ADAM19
7237:ADAM17
7232:ADAM10
7205:3.4.24
7148:Desmin
6963:SPINK1
6910:AFP-L3
6785:CA-125
6762:breast
6745:AFP-L3
6713:CA 242
6703:CA19-9
6675:CA19-9
6154:CFU-GM
6008:T cell
5925:B cell
5685:CD300A
5644:CDw293
5429:CD240D
5290:CD213a
5268:CDw210
5233:CD202b
5207:CDw199
5202:CDw198
4856:CD140b
4288:51–100
3694:P08473
3680:(MeSH)
3665:MEROPS
3646:
3636:
3595:
3587:
3546:
3511:
3470:
3462:
3421:
3413:
3369:
3359:
3318:
3277:
3267:
3236:
3228:
3192:
3184:
3145:
3137:
3101:
3093:
3052:
3044:
3009:
2973:
2965:
2924:
2916:
2881:
2840:
2830:
2791:
2783:
2742:
2732:
2691:
2656:
2648:
2596:
2561:
2530:
2520:
2479:
2403:
2368:
2327:
2319:
2283:
2275:
2239:
2196:"CD10"
2179:
1991:(MMMT)
1785:RB-101
1740:, and
1651:cancer
1642:, and
1616:kidney
1608:kidney
1561:, and
1485:, and
1447:enzyme
1437:) and
1322:search
1320:PubMed
1123:Q61391
1104:Q3KQS6
1100:P08473
996:Entrez
588:BioGPS
275:3q25.2
167:120520
7745:Types
7505:Other
7496:MMP28
7491:MMP27
7486:MMP26
7481:MMP25
7476:MMP24
7461:MMP21
7456:MMP20
7451:MMP19
7446:MMP17
7441:MMP16
7436:MMP15
7431:MMP14
7426:MMP13
7421:MMP12
7416:MMP11
7411:MMP10
7259:ADAM8
7254:ADAM7
7249:ADAM2
7227:ADAM9
7067:hPG80
7024:NMP22
7001:NANOG
6983:hPG80
6968:GOLM1
6920:hPG80
6882:hPG80
6723:hPG80
6685:hPG80
6623:hPG80
6395:CD79a
6356:Blood
6247:CFU-E
6167:CD11c
5991:CD138
5970:CD127
5942:CD79A
5865:CD350
5860:CD349
5855:CD344
5850:CD340
5845:CD339
5840:CD338
5835:CD337
5830:CD336
5825:CD335
5820:CD334
5815:CD333
5810:CD332
5805:CD331
5800:CD329
5795:CD328
5790:CD327
5785:CD326
5780:CD325
5775:CD324
5770:CD322
5765:CD321
5760:CD320
5755:CD318
5750:CD317
5745:CD316
5740:CD315
5735:CD314
5730:CD312
5725:CD309
5720:CD307
5715:CD306
5710:CD305
5705:CD304
5700:CD303
5695:CD302
5690:CD301
5669:CD299
5664:CD298
5659:CD297
5654:CD295
5649:CD294
5639:CD292
5634:CD290
5629:CD289
5624:CD288
5619:CD286
5614:CD284
5609:CD283
5604:CD282
5599:CD281
5594:CD280
5589:CD279
5584:CD278
5579:CD276
5574:CD275
5569:CD274
5564:CD273
5559:CD272
5554:CD271
5549:CD269
5544:CD268
5539:CD267
5534:CD266
5529:CD265
5524:CD264
5519:CD263
5514:CD262
5509:CD261
5504:CD258
5499:CD257
5494:CD256
5489:CD254
5484:CD253
5479:CD252
5463:CD249
5458:CD248
5454:CD247
5449:CD246
5444:CD244
5439:CD243
5434:CD241
5419:CD239
5414:CD238
5409:CD236
5392:CD235
5387:CD234
5382:CD233
5377:CD230
5372:CD229
5367:CD228
5362:CD227
5357:CD226
5352:CD225
5347:CD224
5342:CD223
5337:CD222
5332:CD221
5327:CD220
5312:CD218
5307:CD217
5285:CD212
5263:CD209
5258:CD208
5253:CD207
5248:CD206
5243:CD205
5238:CD204
5228:CD201
5212:CD200
5197:CD197
5192:CD196
5187:CD195
5182:CD194
5177:CD193
5172:CD192
5167:CD191
5162:CD186
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5147:CD183
5142:CD182
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5132:CD180
5115:CD179
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5100:CD174
5078:CD172
5073:CD171
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5063:CD169
5058:CD168
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5036:CD166
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