Knowledge (XXG)

CD43

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Serrador JM, Nieto M, Alonso-Lebrero JL, del Pozo MA, Calvo J, Furthmayr H, Schwartz-Albiez R, Lozano F, González-Amaro R, Sánchez-Mateos P, Sánchez-Madrid F (June 1998). "CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts".
1164:, since the malignant cells in this condition are often CD43 positive, and may be difficult to stain with other antibodies. Because it stains granulocytes and their precursors, it is also an effective marker for 1152:, CD43 can be demonstrated in the paracortical T-cells of healthy lymph nodes and tonsils; it is also positive in a range of lymphoid and myeloid tumours. Although it is present in over 90% of T-cell 1984:
Serrador JM, Nieto M, Alonso-Lebrero JL, et al. (1998). "CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts".
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Seveau S, Keller H, Maxfield FR, et al. (2000). "Neutrophil polarity and locomotion are associated with surface redistribution of leukosialin (CD43), an antiadhesive membrane molecule".
3109: 1865:"Regulation mechanism of ERM (ezrin/radixin/moesin) protein/plasma membrane association: possible involvement of phosphatidylinositol turnover and Rho-dependent signaling pathway" 1746:
Park JK, Rosenstein YJ, Remold-O'Donnell E, et al. (1991). "Enhancement of T-cell activation by the CD43 molecule whose expression is defective in Wiskott-Aldrich syndrome".
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Srinivas RV, Su T, Trimble LA, et al. (1996). "Enhanced susceptibility to human immunodeficiency virus infection in CD4+ T lymphocytes genetically deficient in CD43".
257: 156: 4868: 3099: 3079: 1908:"Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2" 1511:"Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2" 794: 79: 775: 3941: 2265: 2241: 4285: 3672: 3660: 3438: 4887: 3724: 3719: 3665: 3445: 2226: 1454: 1265: 1247: 1136:, which appears to be important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation. 4892: 3178: 3104: 2234: 1951:"T cell activation through the CD43 molecule leads to Vav tyrosine phosphorylation and mitogen-activated protein kinase pathway activation" 4861: 4662: 4207: 4202: 4197: 4192: 3119: 243: 1017: 1010: 4702: 4172: 2208: 220: 1793:"Structure of the human sialophorin (CD43) gene. Identification of features atypical of genes encoding integral membrane proteins" 1361:"Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome" 4552: 3408: 1286: 1177: 4902: 3976: 3470: 3156: 1234: 1213: 2122:"CD43-mediated signals induce DNA binding activity of AP-1, NF-AT, and NFkappa B transcription factors in human T lymphocytes" 4854: 3615: 3151: 142: 117: 1613:
Rosenstein Y, Park JK, Hahn WC, et al. (1992). "CD43, a molecule defective in Wiskott-Aldrich syndrome, binds ICAM-1".
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Fukuda M, Carlsson SR (1987). "Leukosialin, a major sialoglycoprotein on human leukocytes as differentiation antigens".
59: 2157:"Cutting edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor sialoadhesin (Siglec-1)" 1713:"A short, novel promoter sequence confers the expression of human leukosialin, a major sialoglycoprotein on leukocytes" 1660:"Amino acid sequence of human plasma galactoglycoprotein: identity with the extracellular region of CD43 (sialophorin)" 4799: 4278: 3124: 4789: 3836: 2261: 1081: 256: 155: 4752: 4712: 2702: 1584:
Rogaev EI, Keryanov SA (1993). "Unusual variability of the complex dinucleotide repeat block at the SPN locus".
1302:"Characterization of cDNAs encoding human leukosialin and localization of the leukosialin gene to chromosome 16" 249: 148: 4692: 4667: 3886: 2781: 2201: 839: 67: 3850: 820: 4263: 4727: 4271: 3193: 3188: 3183: 3173: 2480: 2408: 1161: 2537: 2455: 131: 3774: 3487: 1755: 1671: 1622: 1372: 1359:
Shelley CS, Remold-O'Donnell E, Davis AE, Bruns GA, Rosen FS, Carroll MC, Whitehead AS (April 1989).
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Pallant A, Eskenazi A, Mattei MG, Fournier RE, Carlsson SR, Fukuda M, Frelinger JG (February 1989).
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Remold-O'Donnell E, Rosen FS (1990). "Sialophorin (CD43) and the Wiskott–Aldrich syndrome".
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Yonemura S, Hirao M, Doi Y, Takahashi N, Kondo T, Tsukita S, Tsukita S (February 1998).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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Sialophorin (leukosialin) is a major sialoglycoprotein on the surface of human
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antigen. However, it may be useful as part of a panel to demonstrate B-cell
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Santana MA, Pedraza-Alva G, Olivares-Zavaleta N, et al. (2000).
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Defects in the CD43 molecule are associated with the development of
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Leong, Anthony S-Y, Cooper, Kumarason, Leong, F Joel W-M (2003).
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Shelley CS, Remold-O'Donnell E, Rosen FS, Whitehead AS (1990).
3759: 2371: 2359: 2354: 2349: 2339: 2312: 2280: 1148:. It also appears in about 25% of intestinal MALTomas. Using 1949:
Pedraza-Alva G, MĂ©rida LB, Burakoff SJ, Rosenstein Y (1998).
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van den Berg TK, Nath D, Ziltener HJ, et al. (2001).
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Fratazzi C, Manjunath N, Arbeit RD, et al. (2000).
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Schmid K, Hediger MA, Brossmer R, et al. (1992).
484: 4650: 4628: 4600: 4543: 4516: 4484: 4475: 4430: 4322: 4313: 4065: 3859: 3608: 3292: 3015: 2675: 2273: 982: 957: 927: 902: 1287:"Entrez Gene: SPN sialophorin (leukosialin, CD43)" 1226: 1224: 1222: 1205: 1203: 1201: 266: 165: 1906:Yonemura S, Hirao M, Doi Y, et al. (1998). 625:negative regulation of type IV hypersensitivity 50:, CD43, GALGP, GPL115, LSN, sialophorin, LEU-22 1863:Hirao M, Sato N, Kondo T, et al. (1996). 1468: 1466: 1231:GRCm38: Ensembl release 89: ENSMUSG00000051457 620:positive regulation of protein phosphorylation 4862: 4279: 2242: 650:establishment or maintenance of cell polarity 8: 2013:Pace KE, Lee C, Stewart PL, Baum LG (1999). 1210:GRCh38: Ensembl release 89: ENSG00000197471 680:positive regulation of T cell proliferation 665:negative regulation of T cell proliferation 4869: 4855: 4481: 4319: 4286: 4272: 4264: 2249: 2235: 2227: 735: 510: 307: 206: 103: 2266:list of human clusters of differentiation 2200:at the U.S. National Library of Medicine 2172: 2137: 2102: 2030: 1966: 1931: 1888: 1816: 1728: 1693: 1683: 1534: 1394: 1384: 1335: 1325: 528:transmembrane signaling receptor activity 1281: 1279: 700:negative regulation of T cell activation 4592:Structural maintenance of chromosomes 3 1197: 695:regulation of defense response to virus 660:cell surface receptor signaling pathway 18:Mammalian protein found in Homo sapiens 20: 569:integral component of plasma membrane 271: 232: 227: 170: 129: 124: 7: 4823: 4821: 615:negative regulation of cell adhesion 4841:. You can help Knowledge (XXG) by 979: 954: 924: 899: 875: 856: 830: 811: 785: 766: 489: 407: 345: 324: 14: 4703:Cholesterylester transfer protein 4553:Chondroitin sulfate proteoglycans 1092:that in humans is encoded by the 4825: 640:negative thymic T cell selection 594:external side of plasma membrane 255: 248: 242: 219: 154: 147: 141: 116: 554:integral component of membrane 473:More reference expression data 1: 1730:10.1016/S0021-9258(18)93000-0 1447:Manual of Diagnostic Cytology 685:regulation of immune response 670:defense response to bacterium 240: 139: 4888:Genes on human chromosome 16 1664:Proc. Natl. Acad. Sci. U.S.A 1365:Proc. Natl. Acad. Sci. U.S.A 1306:Proc. Natl. Acad. Sci. U.S.A 4893:Clusters of differentiation 4800:Tumor necrosis factor alpha 2262:clusters of differentiation 2174:10.4049/jimmunol.166.6.3637 2032:10.4049/jimmunol.163.7.3801 1836:AIDS Res. Hum. Retroviruses 690:apoptotic signaling pathway 4919: 4820: 4790:Thyroxine-binding proteins 2219:gene details page in the 1082:cluster of differentiation 538:heat shock protein binding 4753:Serum amyloid P component 4713:Colony-stimulating factor 1998:10.1182/blood.V91.12.4632 1711:Kudo S, Fukuda M (1991). 1488:10.1182/blood.V91.12.4632 1266:"Mouse PubMed Reference:" 1248:"Human PubMed Reference:" 1056: 1051: 1047: 1040: 1024: 1018:Chr 7: 126.73 – 126.74 Mb 1005: 986: 961: 950: 931: 906: 895: 882: 878: 863: 859: 850: 837: 833: 818: 814: 805: 792: 788: 773: 769: 760: 745: 738: 734: 718: 655:cellular defense response 513: 509: 497: 492: 483: 470: 419: 410: 357: 348: 318: 310: 306: 289: 276: 239: 218: 209: 205: 188: 175: 138: 115: 106: 102: 57: 54: 44: 37: 32: 28: 23: 4693:B-cell activating factor 4668:Alpha 1-antichymotrypsin 2202:Medical Subject Headings 2062:10.1182/blood.V95.8.2462 1968:10.1074/jbc.273.23.14218 1848:10.1089/aid.1995.11.1015 1146:Wiskott–Aldrich syndrome 1011:Chr 16: 29.66 – 29.67 Mb 397:internal globus pallidus 373:tendon of biceps brachii 1176:CD43 has been shown to 4903:Membrane protein stubs 4837:–related article is a 4728:Membrane glycoproteins 2139:10.1074/jbc.M005231200 1386:10.1073/pnas.86.8.2819 1327:10.1073/pnas.86.4.1328 1162:lymphoblastic lymphoma 439:mesenteric lymph nodes 393:triceps brachii muscle 381:pancreatic ductal cell 2095:10.1084/jem.192.2.183 1924:10.1083/jcb.140.4.885 1685:10.1073/pnas.89.2.663 1527:10.1083/jcb.140.4.885 1140:Clinical significance 630:response to protozoan 589:extracellular exosome 533:Hsp70 protein binding 132:Chromosome 16 (human) 2213:genome location and 1881:10.1083/jcb.135.1.37 1150:immunohistochemistry 635:T cell costimulation 273:7 F3|7 69.35 cM 234:Chromosome 7 (mouse) 4733:Myelin protein zero 4658:Activin and inhibin 4458:Phytohaemagglutinin 2221:UCSC Genome Browser 1760:1991Natur.350..706P 1676:1992PNAS...89..663S 1627:1991Natur.354..233R 1598:10.1093/hmg/1.8.657 1377:1989PNAS...86.2819S 1318:1989PNAS...86.1328P 710:signal transduction 705:leukocyte migration 599:extracellular space 459:submandibular gland 4683:Asialoglycoprotein 840:ENSMUSG00000051457 608:Biological process 547:Cellular component 521:Molecular function 451:tibiofemoral joint 361:buccal mucosa cell 4850: 4849: 4818: 4817: 4758:Sialoglycoprotein 4646: 4645: 4587:Platelet factor 4 4471: 4470: 4261: 4260: 1809:10.1042/bj2700569 1456:978-1-84110-100-2 1067: 1066: 1063: 1062: 1036: 1035: 1001: 1000: 976: 975: 946: 945: 921: 920: 891: 890: 872: 871: 846: 845: 827: 826: 801: 800: 782: 781: 730: 729: 574:basement membrane 505: 504: 501: 500: 479: 478: 466: 465: 404: 403: 385:bone marrow cells 302: 301: 201: 200: 4910: 4871: 4864: 4857: 4835:membrane protein 4829: 4822: 4673:Apolipoprotein H 4482: 4443:Intrinsic factor 4320: 4288: 4281: 4274: 4265: 2251: 2244: 2237: 2228: 2186: 2176: 2151: 2141: 2116: 2106: 2073: 2044: 2034: 2009: 1980: 1970: 1961:(23): 14218–24. 1945: 1935: 1902: 1892: 1859: 1830: 1820: 1787: 1768:10.1038/350706a0 1742: 1732: 1707: 1697: 1687: 1654: 1635:10.1038/354233a0 1609: 1580: 1549: 1548: 1538: 1506: 1500: 1499: 1470: 1461: 1460: 1442: 1436: 1435: 1415: 1409: 1408: 1398: 1388: 1356: 1350: 1349: 1339: 1329: 1297: 1291: 1290: 1283: 1274: 1273: 1262: 1256: 1255: 1244: 1238: 1228: 1217: 1207: 1049: 1048: 1020: 1013: 996: 980: 971: 955: 951:RefSeq (protein) 941: 925: 916: 900: 876: 857: 831: 812: 786: 767: 736: 511: 490: 475: 415: 413:Top expressed in 408: 353: 351:Top expressed in 346: 325: 308: 298: 285: 274: 259: 252: 246: 235: 223: 207: 197: 184: 173: 158: 151: 145: 134: 120: 104: 98: 49: 42: 21: 4918: 4917: 4913: 4912: 4911: 4909: 4908: 4907: 4878: 4877: 4876: 4875: 4819: 4814: 4642: 4624: 4596: 4539: 4512: 4467: 4426: 4309: 4292: 4262: 4257: 4061: 3855: 3604: 3288: 3011: 2671: 2269: 2255: 2194: 2189: 2154: 2132:(40): 31460–8. 2119: 2076: 2047: 2012: 1992:(12): 4632–44. 1983: 1948: 1905: 1862: 1833: 1790: 1754:(6320): 706–9. 1745: 1710: 1657: 1621:(6350): 233–5. 1612: 1586:Hum. Mol. Genet 1583: 1562: 1558: 1556:Further reading 1553: 1552: 1508: 1507: 1503: 1482:(12): 4632–44. 1472: 1471: 1464: 1457: 1444: 1443: 1439: 1420:Immunodefic Rev 1417: 1416: 1412: 1358: 1357: 1353: 1299: 1298: 1294: 1285: 1284: 1277: 1264: 1263: 1259: 1246: 1245: 1241: 1229: 1220: 1208: 1199: 1194: 1174: 1142: 1118: 1058:View/Edit Mouse 1053:View/Edit Human 1016: 1009: 1006:Location (UCSC) 992: 988: 967: 963: 937: 933: 912: 908: 821:ENSG00000197471 714: 675:immune response 603: 564:plasma membrane 542: 471: 462: 457: 453: 449: 445: 441: 437: 433: 429: 425: 411: 400: 395: 391: 387: 383: 379: 375: 371: 367: 363: 349: 293: 280: 272: 262: 261: 260: 253: 233: 210:Gene location ( 192: 179: 171: 161: 160: 159: 152: 130: 107:Gene location ( 96:SPN - orthologs 58: 45: 38: 19: 12: 11: 5: 4916: 4914: 4906: 4905: 4900: 4895: 4890: 4880: 4879: 4874: 4873: 4866: 4859: 4851: 4848: 4847: 4830: 4816: 4815: 4813: 4812: 4807: 4802: 4797: 4792: 4787: 4782: 4780:Thrombopoietin 4777: 4776: 4775: 4770: 4765: 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2483: 2478: 2473: 2468: 2463: 2458: 2453: 2448: 2443: 2438: 2437: 2436: 2431: 2421: 2416: 2411: 2406: 2405: 2404: 2399: 2394: 2389: 2379: 2374: 2369: 2368: 2367: 2357: 2352: 2347: 2342: 2337: 2336: 2335: 2330: 2325: 2315: 2310: 2309: 2308: 2303: 2298: 2293: 2288: 2277: 2275: 2271: 2270: 2256: 2254: 2253: 2246: 2239: 2231: 2225: 2224: 2205: 2193: 2192:External links 2190: 2188: 2187: 2167:(6): 3637–40. 2152: 2117: 2074: 2056:(8): 2462–70. 2045: 2025:(7): 3801–11. 2010: 1981: 1946: 1903: 1860: 1842:(9): 1015–21. 1831: 1788: 1743: 1723:(13): 8483–9. 1708: 1655: 1610: 1581: 1559: 1557: 1554: 1551: 1550: 1501: 1462: 1455: 1437: 1410: 1371:(8): 2819–23. 1351: 1312:(4): 1328–32. 1292: 1275: 1257: 1239: 1218: 1196: 1195: 1193: 1190: 1173: 1170: 1141: 1138: 1117: 1114: 1072:also known as 1065: 1064: 1061: 1060: 1055: 1045: 1044: 1038: 1037: 1034: 1033: 1031: 1029: 1022: 1021: 1014: 1007: 1003: 1002: 999: 998: 984: 983: 977: 974: 973: 959: 958: 952: 948: 947: 944: 943: 929: 928: 922: 919: 918: 904: 903: 897: 893: 892: 889: 888: 880: 879: 873: 870: 869: 861: 860: 854: 848: 847: 844: 843: 835: 834: 828: 825: 824: 816: 815: 809: 803: 802: 799: 798: 790: 789: 783: 780: 779: 771: 770: 764: 758: 757: 752: 747: 743: 742: 732: 731: 728: 727: 716: 715: 713: 712: 707: 702: 697: 692: 687: 682: 677: 672: 667: 662: 657: 652: 647: 642: 637: 632: 627: 622: 617: 611: 609: 605: 604: 602: 601: 596: 591: 586: 581: 576: 571: 566: 561: 556: 550: 548: 544: 543: 541: 540: 535: 530: 524: 522: 518: 517: 507: 506: 503: 502: 499: 498: 495: 494: 487: 481: 480: 477: 476: 468: 467: 464: 463: 461: 460: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 417: 416: 405: 402: 401: 399: 398: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 355: 354: 342: 341: 333: 322: 316: 315: 312:RNA expression 304: 303: 300: 299: 291: 287: 286: 278: 275: 270: 264: 263: 254: 247: 241: 237: 236: 231: 225: 224: 216: 215: 203: 202: 199: 198: 190: 186: 185: 177: 174: 169: 163: 162: 153: 146: 140: 136: 135: 128: 122: 121: 113: 112: 100: 99: 56: 52: 51: 43: 35: 34: 30: 29: 26: 25: 17: 13: 10: 9: 6: 4: 3: 2: 4915: 4904: 4901: 4899: 4896: 4894: 4891: 4889: 4886: 4885: 4883: 4872: 4867: 4865: 4860: 4858: 4853: 4852: 4846: 4844: 4840: 4836: 4831: 4828: 4824: 4811: 4808: 4806: 4803: 4801: 4798: 4796: 4793: 4791: 4788: 4786: 4785:Thyroglobulin 4783: 4781: 4778: 4774: 4773:Glycophorin C 4771: 4769: 4766: 4764: 4761: 4760: 4759: 4756: 4754: 4751: 4749: 4746: 4744: 4741: 4739: 4736: 4734: 4731: 4729: 4726: 4724: 4721: 4719: 4716: 4714: 4711: 4709: 4706: 4704: 4701: 4699: 4696: 4694: 4691: 4689: 4686: 4684: 4681: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4659: 4656: 4655: 4653: 4649: 4639: 4636: 4635: 4633: 4631: 4627: 4621: 4618: 4616: 4613: 4611: 4608: 4607: 4605: 4603: 4599: 4593: 4590: 4588: 4585: 4583: 4580: 4578: 4575: 4573: 4570: 4568: 4565: 4563: 4560: 4558: 4554: 4551: 4550: 4548: 4546: 4542: 4536: 4533: 4531: 4528: 4527: 4525: 4523: 4519: 4515: 4509: 4506: 4504: 4501: 4499: 4496: 4495: 4493: 4491: 4487: 4483: 4480: 4478: 4477:Proteoglycans 4474: 4464: 4461: 4459: 4456: 4454: 4453:Peptidoglycan 4451: 4449: 4446: 4444: 4441: 4439: 4436: 4435: 4433: 4429: 4423: 4420: 4418: 4415: 4413: 4410: 4408: 4405: 4403: 4400: 4398: 4395: 4393: 4390: 4388: 4385: 4383: 4380: 4378: 4375: 4373: 4370: 4368: 4365: 4363: 4360: 4358: 4355: 4353: 4350: 4348: 4345: 4343: 4340: 4338: 4335: 4333: 4330: 4329: 4327: 4325: 4321: 4318: 4316: 4312: 4308: 4307:glycopeptides 4304: 4303:glycoproteins 4300: 4296: 4289: 4284: 4282: 4277: 4275: 4270: 4269: 4266: 4254: 4251: 4249: 4246: 4244: 4241: 4239: 4236: 4234: 4231: 4229: 4226: 4224: 4221: 4219: 4216: 4214: 4211: 4209: 4206: 4204: 4201: 4199: 4196: 4194: 4191: 4189: 4186: 4184: 4181: 4179: 4176: 4174: 4171: 4169: 4166: 4164: 4161: 4159: 4156: 4154: 4151: 4149: 4146: 4144: 4141: 4139: 4136: 4134: 4131: 4129: 4126: 4124: 4121: 4119: 4116: 4114: 4111: 4109: 4106: 4104: 4101: 4099: 4096: 4094: 4091: 4089: 4086: 4084: 4081: 4079: 4076: 4074: 4071: 4070: 4068: 4064: 4058: 4055: 4053: 4050: 4048: 4045: 4043: 4040: 4038: 4035: 4033: 4030: 4028: 4025: 4023: 4020: 4018: 4015: 4013: 4010: 4008: 4005: 4003: 4000: 3998: 3995: 3993: 3990: 3988: 3985: 3983: 3980: 3978: 3975: 3973: 3970: 3968: 3965: 3963: 3960: 3958: 3955: 3953: 3950: 3948: 3945: 3943: 3940: 3938: 3935: 3933: 3930: 3928: 3925: 3923: 3920: 3918: 3915: 3913: 3910: 3908: 3905: 3903: 3900: 3898: 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3865: 3864: 3862: 3858: 3852: 3849: 3847: 3843: 3840: 3838: 3835: 3833: 3830: 3828: 3825: 3823: 3820: 3818: 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3795: 3791: 3788: 3786: 3783: 3782: 3781: 3778: 3776: 3773: 3771: 3768: 3766: 3763: 3761: 3758: 3756: 3753: 3751: 3748: 3746: 3743: 3741: 3738: 3736: 3733: 3731: 3728: 3726: 3723: 3721: 3718: 3716: 3713: 3710: 3707: 3705: 3701: 3698: 3696: 3693: 3689: 3686: 3684: 3681: 3680: 3679: 3676: 3674: 3671: 3667: 3664: 3662: 3659: 3658: 3657: 3654: 3652: 3649: 3647: 3644: 3642: 3639: 3637: 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3212: 3210: 3207: 3205: 3202: 3200: 3197: 3195: 3192: 3190: 3187: 3185: 3182: 3180: 3177: 3175: 3172: 3170: 3167: 3165: 3162: 3158: 3155: 3153: 3150: 3149: 3148: 3145: 3141: 3138: 3136: 3133: 3132: 3131: 3128: 3126: 3123: 3121: 3118: 3116: 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3091: 3088: 3086: 3083: 3081: 3078: 3076: 3073: 3071: 3068: 3064: 3061: 3059: 3056: 3055: 3054: 3051: 3049: 3046: 3044: 3041: 3039: 3036: 3034: 3031: 3029: 3026: 3024: 3021: 3020: 3018: 3014: 3008: 3005: 3003: 3000: 2998: 2995: 2993: 2990: 2988: 2985: 2983: 2980: 2978: 2975: 2973: 2970: 2968: 2964: 2961: 2959: 2956: 2954: 2951: 2949: 2946: 2944: 2941: 2939: 2936: 2932: 2929: 2927: 2924: 2922: 2919: 2917: 2914: 2912: 2909: 2907: 2904: 2903: 2902: 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2882: 2879: 2877: 2874: 2870: 2867: 2865: 2862: 2861: 2860: 2857: 2855: 2852: 2850: 2847: 2845: 2842: 2840: 2837: 2835: 2832: 2830: 2827: 2825: 2822: 2820: 2817: 2813: 2810: 2808: 2805: 2803: 2800: 2798: 2795: 2793: 2790: 2788: 2785: 2784: 2783: 2780: 2776: 2773: 2771: 2768: 2766: 2763: 2762: 2761: 2758: 2756: 2753: 2749: 2746: 2744: 2741: 2739: 2736: 2735: 2734: 2731: 2729: 2726: 2724: 2721: 2719: 2716: 2714: 2711: 2709: 2706: 2704: 2701: 2699: 2696: 2694: 2691: 2689: 2686: 2684: 2681: 2680: 2678: 2674: 2668: 2665: 2661: 2658: 2656: 2653: 2651: 2648: 2646: 2643: 2641: 2638: 2636: 2633: 2632: 2631: 2628: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2606: 2603: 2601: 2598: 2594: 2591: 2589: 2586: 2584: 2581: 2579: 2576: 2575: 2574: 2571: 2569: 2566: 2564: 2561: 2559: 2556: 2554: 2551: 2549: 2546: 2544: 2541: 2539: 2536: 2534: 2531: 2529: 2526: 2522: 2519: 2517: 2514: 2513: 2512: 2509: 2507: 2504: 2502: 2499: 2497: 2494: 2492: 2489: 2487: 2484: 2482: 2479: 2477: 2474: 2472: 2469: 2467: 2464: 2462: 2459: 2457: 2454: 2452: 2449: 2447: 2444: 2442: 2439: 2435: 2432: 2430: 2427: 2426: 2425: 2422: 2420: 2417: 2415: 2412: 2410: 2407: 2403: 2400: 2398: 2395: 2393: 2390: 2388: 2385: 2384: 2383: 2380: 2378: 2375: 2373: 2370: 2366: 2363: 2362: 2361: 2358: 2356: 2353: 2351: 2348: 2346: 2343: 2341: 2338: 2334: 2331: 2329: 2326: 2324: 2321: 2320: 2319: 2316: 2314: 2311: 2307: 2304: 2302: 2299: 2297: 2294: 2292: 2289: 2287: 2284: 2283: 2282: 2279: 2278: 2276: 2272: 2267: 2263: 2259: 2252: 2247: 2245: 2240: 2238: 2233: 2232: 2229: 2222: 2218: 2217: 2212: 2211: 2206: 2203: 2199: 2196: 2195: 2191: 2184: 2180: 2175: 2170: 2166: 2162: 2158: 2153: 2149: 2145: 2140: 2135: 2131: 2127: 2126:J. Biol. Chem 2123: 2118: 2114: 2110: 2105: 2100: 2096: 2092: 2089:(2): 183–92. 2088: 2084: 2080: 2075: 2071: 2067: 2063: 2059: 2055: 2051: 2046: 2042: 2038: 2033: 2028: 2024: 2020: 2016: 2011: 2007: 2003: 1999: 1995: 1991: 1987: 1982: 1978: 1974: 1969: 1964: 1960: 1956: 1955:J. Biol. Chem 1952: 1947: 1943: 1939: 1934: 1929: 1925: 1921: 1918:(4): 885–95. 1917: 1913: 1909: 1904: 1900: 1896: 1891: 1886: 1882: 1878: 1874: 1870: 1866: 1861: 1857: 1853: 1849: 1845: 1841: 1837: 1832: 1828: 1824: 1819: 1814: 1810: 1806: 1803:(3): 569–76. 1802: 1798: 1794: 1789: 1785: 1781: 1777: 1773: 1769: 1765: 1761: 1757: 1753: 1749: 1744: 1740: 1736: 1731: 1726: 1722: 1718: 1717:J. Biol. Chem 1714: 1709: 1705: 1701: 1696: 1691: 1686: 1681: 1677: 1673: 1669: 1665: 1661: 1656: 1652: 1648: 1644: 1640: 1636: 1632: 1628: 1624: 1620: 1616: 1611: 1607: 1603: 1599: 1595: 1591: 1587: 1582: 1578: 1574: 1571:(6): 335–43. 1570: 1566: 1561: 1560: 1555: 1546: 1542: 1537: 1532: 1528: 1524: 1521:(4): 885–95. 1520: 1516: 1512: 1505: 1502: 1497: 1493: 1489: 1485: 1481: 1477: 1469: 1467: 1463: 1458: 1452: 1448: 1441: 1438: 1433: 1429: 1426:(2): 151–74. 1425: 1421: 1414: 1411: 1406: 1402: 1397: 1392: 1387: 1382: 1378: 1374: 1370: 1366: 1362: 1355: 1352: 1347: 1343: 1338: 1333: 1328: 1323: 1319: 1315: 1311: 1307: 1303: 1296: 1293: 1288: 1282: 1280: 1276: 1271: 1267: 1261: 1258: 1253: 1249: 1243: 1240: 1236: 1232: 1227: 1225: 1223: 1219: 1215: 1211: 1206: 1204: 1202: 1198: 1191: 1189: 1187: 1183: 1179: 1171: 1169: 1167: 1163: 1159: 1155: 1151: 1147: 1139: 1137: 1135: 1134:B lymphocytes 1131: 1127: 1123: 1122:T lymphocytes 1115: 1113: 1111: 1107: 1103: 1099: 1095: 1091: 1088:cell surface 1087: 1086:transmembrane 1083: 1079: 1075: 1071: 1059: 1054: 1050: 1046: 1043: 1039: 1032: 1030: 1027: 1023: 1019: 1015: 1012: 1008: 1004: 997: 995: 991: 985: 981: 978: 972: 970: 966: 960: 956: 953: 949: 942: 940: 936: 930: 926: 923: 917: 915: 911: 905: 901: 898: 896:RefSeq (mRNA) 894: 887: 886: 881: 877: 874: 868: 867: 862: 858: 855: 853: 849: 842: 841: 836: 832: 829: 823: 822: 817: 813: 810: 808: 804: 797: 796: 791: 787: 784: 778: 777: 772: 768: 765: 763: 759: 756: 753: 751: 748: 744: 741: 737: 733: 726: 722: 717: 711: 708: 706: 703: 701: 698: 696: 693: 691: 688: 686: 683: 681: 678: 676: 673: 671: 668: 666: 663: 661: 658: 656: 653: 651: 648: 646: 643: 641: 638: 636: 633: 631: 628: 626: 623: 621: 618: 616: 613: 612: 610: 607: 606: 600: 597: 595: 592: 590: 587: 585: 582: 580: 577: 575: 572: 570: 567: 565: 562: 560: 557: 555: 552: 551: 549: 546: 545: 539: 536: 534: 531: 529: 526: 525: 523: 520: 519: 516: 515:Gene ontology 512: 508: 496: 491: 488: 486: 482: 474: 469: 458: 455:body of femur 454: 450: 446: 442: 438: 434: 430: 426: 422: 421: 418: 414: 409: 406: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 359: 356: 352: 347: 344: 343: 340: 338: 334: 332: 331: 327: 326: 323: 321: 317: 313: 309: 305: 297: 292: 288: 284: 279: 269: 265: 258: 251: 245: 238: 230: 226: 222: 217: 213: 208: 204: 196: 191: 187: 183: 178: 168: 164: 157: 150: 144: 137: 133: 127: 123: 119: 114: 110: 105: 101: 97: 93: 89: 85: 81: 77: 73: 69: 65: 61: 53: 48: 41: 36: 31: 27: 22: 16: 4843:expanding it 4832: 4762: 4698:4-1BB ligand 4610:Fibromodulin 4331: 4315:Mucoproteins 3779: 3699: 3677: 3655: 3502: 3465: 3428: 3381: 3351: 3324: 3146: 3052: 2900: 2629: 2599: 2381: 2215: 2209: 2198:CD43+antigen 2164: 2160: 2129: 2125: 2086: 2082: 2053: 2049: 2022: 2018: 1989: 1985: 1958: 1954: 1915: 1912:J. Cell Biol 1911: 1875:(1): 37–51. 1872: 1869:J. Cell Biol 1868: 1839: 1835: 1800: 1796: 1751: 1747: 1720: 1716: 1670:(2): 663–7. 1667: 1663: 1618: 1614: 1589: 1585: 1568: 1564: 1518: 1515:J. Cell Biol 1514: 1504: 1479: 1475: 1446: 1440: 1423: 1419: 1413: 1368: 1364: 1354: 1309: 1305: 1295: 1269: 1260: 1251: 1242: 1175: 1172:Interactions 1143: 1130:granulocytes 1119: 1105: 1101: 1097: 1093: 1077: 1073: 1069: 1068: 990:NP_001032899 987: 965:NP_001025459 962: 935:NM_001037810 932: 910:NM_001030288 907: 883: 864: 838: 819: 793: 774: 754: 749: 579:cell surface 335: 328: 294:126,736,995 281:126,731,404 55:External IDs 15: 4810:Vitronectin 4805:Uteroglobin 4795:Transcortin 4768:Glycophorin 4738:Osteonectin 4723:Lactoferrin 4448:Orosomucoid 4438:Haptoglobin 2083:J. Exp. Med 1132:, and some 1074:sialophorin 1070:Leukosialin 427:granulocyte 365:granulocyte 193:29,670,876 180:29,662,979 33:Identifiers 4882:Categories 4638:Syndecan 1 2264:(see also 2161:J. Immunol 2019:J. Immunol 1797:Biochem. J 1592:(8): 657. 1237:, May 2017 1216:, May 2017 1192:References 645:chemotaxis 435:lymph node 339:(ortholog) 76:HomoloGene 4748:Protein S 4743:Protein C 4718:Hemopexin 4708:Clusterin 4620:Keratocan 1565:Med. Biol 1168:tumours. 1154:lymphomas 1126:monocytes 1084:43) is a 994:NP_033285 969:NP_003114 939:NM_009259 914:NM_003123 740:Orthologs 389:vena cava 84:GeneCards 4567:Brevican 4562:Neurocan 4557:Aggrecan 4535:Perlecan 4530:Testican 4508:Versican 4503:Biglycan 4463:Ovomucin 2258:Proteins 2183:11238599 2148:10908570 2113:10899905 2070:10753822 2041:10490978 1233:– 1212:– 1178:interact 1116:Function 1042:Wikidata 719:Sources: 559:membrane 369:monocyte 4615:Lumican 4498:Decorin 4295:Protein 4066:301–350 3860:251–300 3812:CD240CE 3609:201–250 3293:151–200 3016:101–150 2104:2193255 2006:9616160 1977:9603925 1942:9472040 1933:2141743 1899:8858161 1890:2121020 1856:8554898 1827:2241892 1818:1131770 1784:4335838 1776:2023632 1756:Bibcode 1739:1827122 1704:1731338 1672:Bibcode 1651:4256329 1643:1683685 1623:Bibcode 1606:1301183 1577:2950285 1545:9472040 1536:2141743 1496:9616160 1432:2223062 1405:2784859 1373:Bibcode 1346:2521952 1314:Bibcode 1235:Ensembl 1214:Ensembl 1166:myeloid 1090:protein 852:UniProt 807:Ensembl 746:Species 725:QuickGO 447:decidua 314:pattern 172:16p11.2 40:Aliases 4898:Mucins 4688:Avidin 4367:MUC5AC 4073:CD300A 4032:CDw293 3817:CD240D 3678:CD213a 3656:CDw210 3621:CD202b 3595:CDw199 3590:CDw198 3244:CD140b 2676:51–100 2207:Human 2204:(MeSH) 2181:  2146:  2111:  2101:  2068:  2039:  2004:  1975:  1940:  1930:  1897:  1887:  1854:  1825:  1815:  1782:  1774:  1748:Nature 1737:  1702:  1692:  1649:  1641:  1615:Nature 1604:  1575:  1543:  1533:  1494:  1453:  1430:  1403:  1396:287010 1393:  1344:  1337:286683 1334:  1186:Moesin 1028:search 1026:PubMed 885:P15702 866:P16150 762:Entrez 584:uropod 485:BioGPS 443:spleen 431:thymus 64:182160 4833:This 4651:Other 4582:CSPG5 4577:CSPG4 4431:Other 4422:MUC20 4417:MUC19 4412:MUC17 4407:MUC16 4402:MUC15 4397:MUC13 4392:MUC12 4372:MUC5B 4357:MUC3B 4352:MUC3A 4337:CD164 4324:Mucin 4253:CD350 4248:CD349 4243:CD344 4238:CD340 4233:CD339 4228:CD338 4223:CD337 4218:CD336 4213:CD335 4208:CD334 4203:CD333 4198:CD332 4193:CD331 4188:CD329 4183:CD328 4178:CD327 4173:CD326 4168:CD325 4163:CD324 4158:CD322 4153:CD321 4148:CD320 4143:CD318 4138:CD317 4133:CD316 4128:CD315 4123:CD314 4118:CD312 4113:CD309 4108:CD307 4103:CD306 4098:CD305 4093:CD304 4088:CD303 4083:CD302 4078:CD301 4057:CD299 4052:CD298 4047:CD297 4042:CD295 4037:CD294 4027:CD292 4022:CD290 4017:CD289 4012:CD288 4007:CD286 4002:CD284 3997:CD283 3992:CD282 3987:CD281 3982:CD280 3977:CD279 3972:CD278 3967:CD276 3962:CD275 3957:CD274 3952:CD273 3947:CD272 3942:CD271 3937:CD269 3932:CD268 3927:CD267 3922:CD266 3917:CD265 3912:CD264 3907:CD263 3902:CD262 3897:CD261 3892:CD258 3887:CD257 3882:CD256 3877:CD254 3872:CD253 3867:CD252 3851:CD249 3846:CD248 3842:CD247 3837:CD246 3832:CD244 3827:CD243 3822:CD241 3807:CD239 3802:CD238 3797:CD236 3780:CD235 3775:CD234 3770:CD233 3765:CD230 3760:CD229 3755:CD228 3750:CD227 3745:CD226 3740:CD225 3735:CD224 3730:CD223 3725:CD222 3720:CD221 3715:CD220 3700:CD218 3695:CD217 3673:CD212 3651:CD209 3646:CD208 3641:CD207 3636:CD206 3631:CD205 3626:CD204 3616:CD201 3600:CD200 3585:CD197 3580:CD196 3575:CD195 3570:CD194 3565:CD193 3560:CD192 3555:CD191 3550:CD186 3545:CD185 3540:CD184 3535:CD183 3530:CD182 3525:CD181 3520:CD180 3503:CD179 3498:CD178 3493:CD177 3488:CD174 3466:CD172 3461:CD171 3456:CD170 3451:CD169 3446:CD168 3429:CD167 3424:CD166 3419:CD164 3414:CD163 3409:CD162 3404:CD161 3399:CD160 3382:CD159 3352:CD158 3347:CD157 3325:CD156 3320:CD155 3315:CD154 3310:CD153 3305:CD152 3300:CD151 3284:CD150 3279:CD148 3274:CD147 3269:CD146 3264:CD144 3259:CD143 3254:CD142 3249:CD141 3239:CD138 3234:CD137 3229:CD136 3224:CD135 3219:CD134 3214:CD133 3209:CD132 3204:CD131 3199:CD130 3194:CD129 3189:CD127 3184:CD126 3179:CD125 3174:CD124 3169:CD123 3164:CD122 3147:CD121 3130:CD120 3125:CD119 3120:CD118 3115:CD117 3110:CD116 3105:CD115 3100:CD114 3095:CD113 3090:CD112 3085:CD111 3080:CD110 3075:CD109 3070:CD108 3053:CD107 3048:CD106 3043:CD105 3038:CD104 3033:CD103 3028:CD102 3023:CD101 3007:CD100 2050:Blood 1986:Blood 1780:S2CID 1695:48299 1647:S2CID 1476:Blood 1180:with 795:20737 755:Mouse 750:Human 721:Amigo 423:blood 377:sperm 337:Mouse 330:Human 277:Start 212:Mouse 176:Start 109:Human 80:36108 72:98384 4839:stub 4763:CD43 4678:CD70 4663:ADAM 4572:CD44 4387:MUC8 4382:MUC7 4377:MUC6 4362:MUC4 4347:MUC2 4342:MUC1 4332:CD43 4305:and 3002:CD99 2997:CD98 2992:CD97 2987:CD96 2982:CD95 2977:CD94 2972:CD93 2967:CD92 2963:CD91 2958:CD90 2953:CD89 2948:CD88 2943:CD87 2938:CD86 2901:CD85 2896:CD84 2891:CD83 2886:CD82 2881:CD81 2876:CD80 2859:CD79 2854:CD78 2849:CD74 2844:CD73 2839:CD72 2834:CD71 2829:CD70 2824:CD69 2819:CD68 2782:CD66 2760:CD64 2755:CD63 2733:CD62 2728:CD61 2723:CD59 2718:CD58 2713:CD57 2708:CD56 2703:CD55 2698:CD54 2693:CD53 2688:CD52 2683:CD51 2667:CD50 2630:CD49 2625:CD48 2620:CD47 2615:CD46 2610:CD45 2605:CD44 2600:CD43 2573:CD42 2568:CD41 2563:CD40 2558:CD39 2553:CD38 2548:CD37 2543:CD36 2538:CD35 2533:CD34 2528:CD33 2511:CD32 2506:CD31 2501:CD30 2496:CD29 2491:CD28 2486:CD27 2481:CD26 2476:CD25 2471:CD24 2466:CD23 2461:CD22 2456:CD21 2451:CD20 2446:CD19 2441:CD18 2424:CD16 2419:CD15 2414:CD14 2409:CD13 2382:CD11 2377:CD10 2274:1–50 2179:PMID 2144:PMID 2109:PMID 2066:PMID 2037:PMID 2002:PMID 1973:PMID 1938:PMID 1895:PMID 1852:PMID 1823:PMID 1772:PMID 1735:PMID 1700:PMID 1639:PMID 1602:PMID 1573:PMID 1541:PMID 1492:PMID 1451:ISBN 1428:PMID 1401:PMID 1342:PMID 1184:and 1110:gene 1104:hori 1100:ialo 1078:CD43 776:6693 320:Bgee 268:Band 229:Chr. 167:Band 126:Chr. 60:OMIM 2372:CD9 2360:CD8 2355:CD7 2350:CD6 2345:CD5 2340:CD4 2318:CD3 2313:CD2 2286:a-c 2281:CD1 2216:SPN 2210:SPN 2169:doi 2165:166 2134:doi 2130:275 2099:PMC 2091:doi 2087:192 2058:doi 2027:doi 2023:163 1994:doi 1963:doi 1959:273 1928:PMC 1920:doi 1916:140 1885:PMC 1877:doi 1873:135 1844:doi 1813:PMC 1805:doi 1801:270 1764:doi 1752:350 1725:doi 1721:266 1690:PMC 1680:doi 1631:doi 1619:354 1594:doi 1531:PMC 1523:doi 1519:140 1484:doi 1391:PMC 1381:doi 1332:PMC 1322:doi 1182:EZR 1158:CD3 1094:SPN 1076:or 493:n/a 290:End 189:End 92:OMA 88:SPN 68:MGI 47:SPN 24:SPN 4884:: 4630:HS 4602:KS 4555:: 4545:CS 4522:CS 4518:HS 4490:DS 4486:CS 4301:: 4297:, 3844:- 2965:- 2306:1E 2301:1D 2296:1B 2291:1A 2260:: 2177:. 2163:. 2159:. 2142:. 2128:. 2124:. 2107:. 2097:. 2085:. 2081:. 2064:. 2054:95 2052:. 2035:. 2021:. 2017:. 2000:. 1990:91 1988:. 1971:. 1957:. 1953:. 1936:. 1926:. 1914:. 1910:. 1893:. 1883:. 1871:. 1867:. 1850:. 1840:11 1838:. 1821:. 1811:. 1799:. 1795:. 1778:. 1770:. 1762:. 1750:. 1733:. 1719:. 1715:. 1698:. 1688:. 1678:. 1668:89 1666:. 1662:. 1645:. 1637:. 1629:. 1617:. 1600:. 1588:. 1569:64 1567:. 1539:. 1529:. 1517:. 1513:. 1490:. 1480:91 1478:. 1465:^ 1422:. 1399:. 1389:. 1379:. 1369:86 1367:. 1363:. 1340:. 1330:. 1320:. 1310:86 1308:. 1304:. 1278:^ 1268:. 1250:. 1221:^ 1200:^ 1188:. 1128:, 1124:, 1112:. 1108:) 723:/ 296:bp 283:bp 195:bp 182:bp 90:; 86:: 82:; 78:: 74:; 70:: 66:; 62:: 4870:e 4863:t 4856:v 4845:. 4520:/ 4488:/ 4287:e 4280:t 4273:v 3790:b 3785:a 3711:) 3709:b 3704:a 3702:( 3688:2 3683:1 3666:b 3661:a 3513:b 3508:a 3481:g 3476:b 3471:a 3439:b 3434:a 3392:c 3387:a 3378:) 3376:k 3371:i 3366:e 3361:d 3356:a 3354:( 3340:c 3335:b 3330:a 3157:b 3152:a 3140:b 3135:a 3063:b 3058:a 2931:k 2926:j 2921:h 2916:e 2911:d 2906:a 2869:b 2864:a 2812:f 2807:e 2802:d 2797:c 2792:b 2787:a 2775:C 2770:B 2765:A 2748:P 2743:L 2738:E 2660:f 2655:e 2650:d 2645:c 2640:b 2635:a 2593:d 2588:c 2583:b 2578:a 2521:B 2516:A 2434:B 2429:A 2402:d 2397:c 2392:b 2387:a 2365:a 2333:ε 2328:δ 2323:Îł 2268:) 2250:e 2243:t 2236:v 2223:. 2185:. 2171:: 2150:. 2136:: 2115:. 2093:: 2072:. 2060:: 2043:. 2029:: 2008:. 1996:: 1979:. 1965:: 1944:. 1922:: 1901:. 1879:: 1858:. 1846:: 1829:. 1807:: 1786:. 1766:: 1758:: 1741:. 1727:: 1706:. 1682:: 1674:: 1653:. 1633:: 1625:: 1608:. 1596:: 1590:1 1579:. 1547:. 1525:: 1498:. 1486:: 1459:. 1434:. 1424:2 1407:. 1383:: 1375:: 1348:. 1324:: 1316:: 1289:. 1272:. 1254:. 1106:n 1102:p 1098:s 1096:( 1080:( 214:) 111:) 94::

Index

Aliases
SPN
OMIM
182160
MGI
98384
HomoloGene
36108
GeneCards
SPN
OMA
SPN - orthologs
Human
Chromosome 16 (human)
Chr.
Chromosome 16 (human)
Chromosome 16 (human)
Genomic location for SPN
Genomic location for SPN
Band
bp
bp
Mouse
Chromosome 7 (mouse)
Chr.
Chromosome 7 (mouse)
Genomic location for SPN
Genomic location for SPN
Band
bp

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