539:
516:
2820:
413:
438:
2700:
2715:
2835:
804:
797:
790:
2685:
545:
444:
2730:
42:
2805:
2790:
2775:
2760:
2745:
5808:
1668:
are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as
68:
2145:"Identification of a talin-binding site in the integrin beta(3) subunit distinct from the NPLY regulatory motif of post-ligand binding functions. The talin n-terminal head domain interacts with the membrane-proximal region of the beta(3) cytoplasmic tail"
2422:
Smith FB, Connor JM, Lee AJ, Cooke A, Lowe GD, Rumley A, et al. (2004). "Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease".
2819:
2699:
3736:
2875:
2714:
2834:
2401:
Charakida M, Tousoulis D, Stefanadis C, Toutouzas P (January 2003). "The impact of platelet glycoprotein IIIa and Ia polymorphisms in cardiovascular thrombotic disease".
552:
451:
2607:
4912:
3726:
2684:
5304:
5791:
3706:
1367:
374:
1348:
4568:
2892:
2868:
5658:
5882:
4299:
1818:"Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa"
5853:
4287:
4065:
5872:
4351:
4346:
4292:
4072:
2853:
2664:
1798:
1780:
5173:
3805:
3731:
2861:
2729:
538:
5396:
4834:
4829:
4824:
4819:
3746:
1574:
4905:
2624:
1567:
5299:
515:
5221:
5216:
4799:
5350:
4035:
1914:
2828:: Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen
5178:
5014:
4603:
4097:
3783:
1767:
1746:
4954:
4242:
3778:
2271:
Bray PF (October 1994). "Inherited diseases of platelet glycoproteins: considerations for rapid molecular characterization".
437:
412:
2096:"Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit"
1763:
2630:
2059:
Fujimoto TT, Katsutani S, Shimomura T, Fujimura K (January 2002). "Novel alternatively spliced form of beta(3)-endonexin".
65:
5254:
4898:
4739:
4211:
4206:
4151:
3885:
3334:
1971:"Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling"
1742:
5206:
4433:
4156:
354:
3751:
2614:
1690:
2510:
Watson SP, Auger JM, McCarty OJ, Pearce AC (August 2005). "GPVI and integrin alphaIIb beta3 signaling in platelets".
551:
450:
5846:
4463:
2888:
1649:
544:
443:
5294:
3329:
2657:
2227:"Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain"
4513:
3408:
2601:
1412:
362:
5389:
4477:
1393:
5753:
5727:
5722:
5717:
5642:
5632:
5573:
5120:
5116:
3820:
3815:
3810:
3800:
3107:
3035:
5839:
5578:
5235:
4979:
4948:
3164:
3082:
1718:
426:
2708:: CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN AVB3 IN COMPLEX WITH AN ARG-GLY-ASP LIGAND
1816:
Sosnoski DM, Emanuel BS, Hawkins AL, van Tuinen P, Ledbetter DH, Nussbaum RL, et al. (June 1988).
5690:
5674:
5605:
5276:
4401:
4114:
2650:
2301:
2020:"Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3"
341:
5286:
5263:
5244:
5226:
4921:
4428:
4247:
2636:
2452:
Fullard JF (2004). "The role of the platelet glycoprotein IIb/IIIa in thrombosis and haemostasis".
2184:
Calderwood DA, Yan B, de Pereda JM, Alvarez BG, Fujioka Y, Liddington RC, et al. (June 2002).
2094:
Shattil SJ, O'Toole T, Eigenthaler M, Thon V, Williams M, Babior BM, et al. (November 1995).
5877:
5382:
4929:
3835:
3569:
2535:
2337:
Sajid M, Stouffer GA (February 2002). "The role of alpha(v)beta3 integrins in vascular healing".
2325:
1896:
386:
1969:
Eliceiri BP, Puente XS, Hood JD, Stupack DG, Schlaepfer DD, Huang XZ, et al. (April 2002).
1550:
1529:
1503:
1482:
5314:
5271:
2578:
2527:
2498:
2469:
2440:
2410:
2389:
2354:
2317:
2280:
2248:
2207:
2166:
2125:
2076:
2041:
2000:
1951:
1888:
1847:
803:
796:
789:
334:
58:
5823:
5679:
5610:
5540:
5535:
5489:
5327:
5322:
4608:
4341:
4262:
3825:
3018:
2944:
2568:
2560:
2519:
2490:
2481:
Cacciari B, Spalluto G (2005). "Non peptidic alphavbeta3 antagonists: recent developments".
2461:
2432:
2379:
2346:
2309:
2238:
2197:
2156:
2115:
2107:
2068:
2031:
1990:
1982:
1941:
1878:
1837:
1829:
631:
562:
506:
461:
382:
4994:
4973:
4959:
4668:
3204:
3199:
3122:
2618:
606:
2597:
2804:
2789:
2774:
2759:
2744:
2305:
5774:
5769:
5748:
5332:
4453:
3875:
3386:
3189:
2723:: CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHA VBETA3 BOUND TO MN2+
2573:
2548:
2384:
2367:
2313:
2143:
Patil S, Jedsadayanmata A, Wencel-Drake JD, Wang W, Knezevic I, Lam SC (October 1999).
2120:
2095:
1995:
1970:
41:
2072:
1930:"Endometrial alterations in endometriosis: a systematic review of putative biomarkers"
1842:
1817:
1282:
1277:
1272:
1267:
1262:
1257:
1252:
1247:
1242:
1237:
1232:
1227:
1222:
1217:
1212:
1207:
1202:
1197:
1192:
1187:
1182:
1177:
1172:
1167:
1162:
1157:
1152:
1147:
1142:
1137:
1132:
1127:
1122:
1117:
1112:
1107:
1102:
1097:
1092:
1087:
1082:
1066:
1061:
1056:
1051:
1046:
1041:
1036:
1031:
1026:
1021:
1016:
1011:
1006:
1001:
996:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
930:
925:
920:
915:
910:
905:
900:
895:
890:
885:
880:
875:
870:
865:
860:
855:
850:
845:
5866:
5819:
5145:
5069:
5024:
4423:
3880:
2971:
2523:
1900:
1678:
832:
2539:
2329:
1093:
positive regulation of vascular endothelial growth factor receptor signaling pathway
5342:
5188:
5153:
4779:
4087:
4077:
3608:
3574:
2843:: A novel adaptation of the integrin PSI domain revealed from its crystal structure
2436:
624:
403:
366:
390:
5196:
5131:
5102:
5084:
5059:
5049:
5004:
4938:
4789:
4438:
4216:
4191:
3890:
3512:
3438:
2912:
1915:"Entrez Gene: ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)"
1803:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1785:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1653:
345:, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT, integrin subunit beta 3, BDPLT24, GT2
1677:
Defectively expressed β3 integrin subunit has been correlated with presence of
707:
5112:
5074:
5034:
5029:
5019:
4719:
4443:
4124:
3865:
3741:
3374:
3369:
3364:
3219:
3003:
523:
420:
370:
2494:
2465:
2161:
2144:
2036:
2019:
5211:
5168:
5163:
5158:
5044:
5039:
4558:
4553:
4548:
4538:
4533:
4528:
4523:
1946:
1929:
1665:
1312:
767:
645:
590:
577:
489:
476:
378:
2611:
2582:
2531:
2502:
2473:
2444:
2414:
2393:
2358:
2350:
2321:
2243:
2226:
2211:
2202:
2185:
2170:
2080:
2004:
1955:
1892:
2284:
2252:
2129:
2111:
2045:
1986:
1851:
1614:
1609:
5405:
5107:
5097:
5092:
4864:
4764:
4578:
4563:
3766:
3761:
3669:
3359:
1598:
1457:
1438:
2693:: CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3
1867:"Platelet-based coagulation: different populations, different functions"
5359:
5201:
4814:
4809:
4804:
4704:
4518:
4508:
4335:
4314:
4309:
4277:
4082:
4002:
3997:
3992:
3987:
3982:
3900:
3593:
3433:
3428:
3423:
3418:
3413:
2884:
1698:
1634:
1424:
1379:
4890:
2186:"The phosphotyrosine binding-like domain of talin activates integrins"
1883:
1866:
1833:
311:
307:
303:
299:
295:
291:
287:
283:
279:
275:
271:
267:
263:
259:
255:
251:
247:
243:
239:
235:
231:
227:
223:
219:
215:
211:
207:
203:
199:
195:
191:
187:
183:
179:
175:
171:
167:
163:
159:
155:
151:
147:
143:
139:
135:
131:
127:
123:
119:
115:
111:
107:
103:
99:
95:
91:
87:
5583:
5469:
5464:
5126:
4983:
4754:
4714:
4699:
4683:
4678:
4658:
4653:
4588:
4396:
4366:
4330:
4321:
4134:
4102:
3966:
3961:
3931:
3910:
3870:
3830:
3696:
3674:
3633:
3557:
3552:
3547:
3542:
3537:
3532:
3401:
3396:
3391:
3339:
3324:
3194:
3184:
3147:
3142:
3060:
3055:
2564:
1582:
1334:
5807:
1273:
regulation of postsynaptic neurotransmitter receptor internalization
17:
1243:
negative regulation of macrophage derived foam cell differentiation
5737:
5732:
5695:
5663:
5637:
5550:
5545:
5530:
5499:
5494:
5484:
5479:
5474:
5459:
5454:
5449:
5444:
5439:
5434:
5429:
5424:
5419:
4968:
4963:
4879:
4854:
4774:
4769:
4759:
4749:
4734:
4729:
4724:
4709:
4663:
4648:
4613:
4598:
4593:
4583:
4503:
4498:
4493:
4472:
4468:
4458:
4371:
4272:
4267:
4226:
4176:
4171:
4166:
4161:
4146:
4139:
4119:
4107:
4050:
4045:
4040:
4030:
4025:
4018:
3956:
3946:
3941:
3936:
3926:
3905:
3895:
3860:
3855:
3850:
3845:
3840:
3795:
3790:
3756:
3721:
3716:
3711:
3701:
3689:
3684:
3664:
3659:
3654:
3649:
3603:
3495:
3490:
3309:
3293:
3286:
3281:
3276:
3271:
3266:
3261:
3236:
3214:
3209:
3102:
3028:
3023:
3013:
1681:, and has been suggested as a putative marker of this condition.
1297:
1293:
5815:
5741:
5699:
5683:
5667:
5614:
5587:
5525:
5520:
5515:
4988:
4874:
4869:
4859:
4849:
4844:
4839:
4794:
4784:
4744:
4673:
4643:
4638:
4633:
4628:
4623:
4618:
4573:
4543:
4448:
4416:
4411:
4391:
4381:
4376:
4361:
4356:
4257:
4252:
4221:
4201:
4196:
4186:
4181:
4060:
4013:
3973:
3628:
3623:
3618:
3613:
3598:
3589:
3584:
3579:
3564:
3522:
3517:
3507:
3502:
3485:
3480:
3475:
3470:
3465:
3460:
3455:
3450:
3445:
3381:
3354:
3349:
3344:
3319:
3314:
3251:
3246:
3241:
3231:
3226:
3179:
3174:
3169:
3159:
3154:
3137:
3132:
3127:
3117:
3112:
3097:
3092:
3087:
3077:
3072:
3067:
3050:
3045:
3040:
2991:
2959:
2954:
2949:
2932:
2927:
2922:
2917:
1706:
1702:
1694:
1641:
358:
5378:
4894:
2857:
2646:
2549:"Structure and function of the platelet integrin alphaIIbbeta3"
812:
4386:
2998:
2986:
2981:
2976:
2966:
2939:
2907:
2642:
5174:
Protein Z-related protease inhibitor (ZPI) (inhibits FX, FXI)
1664:
The ITGB3 protein product is the integrin beta chain beta 3.
1173:
vascular endothelial growth factor receptor signaling pathway
5374:
2366:
Quinn MJ, Byzova TV, Qin J, Topol EJ, Plow EF (June 2003).
1928:
May KE, Villar J, Kirtley S, Kennedy SH, Becker CM (2011).
1183:
positive regulation of peptidyl-tyrosine phosphorylation
614:
5827:
2292:
Bennett JS (2001). "Platelet-fibrinogen interactions".
1865:
Heemskerk JW, Mattheij NJ, Cosemans JM (January 2013).
5179:
Tissue factor pathway inhibitor (TFPI) (inhibits FIII)
1113:
positive regulation of endothelial cell proliferation
846:
vascular endothelial growth factor receptor 2 binding
779:
2738:: Platelet integrin alfaIIb-beta3 cytoplasmic domain
1083:
negative regulation of lipoprotein metabolic process
5762:
5710:
5651:
5625:
5598:
5566:
5559:
5508:
5412:
5341:
5313:
5285:
5262:
5253:
5187:
5144:
5083:
5058:
5003:
4937:
4928:
4692:
4486:
4235:
3919:
3642:
3302:
2900:
1543:
1522:
1496:
1475:
5245:Thrombin-activatable fibrinolysis inhibitor (TAFI)
2372:Arteriosclerosis, Thrombosis, and Vascular Biology
1759:
1757:
1755:
1738:
1736:
1734:
5305:Activated protein C–protein C inhibitor (APC–PCI)
1158:positive regulation of endothelial cell migration
561:
460:
5154:Antithrombin (inhibits FII, FIX, FX, FXI, FXII)
876:platelet-derived growth factor receptor binding
2225:Naik UP, Patel PM, Parise LV (February 1997).
1764:GRCm38: Ensembl release 89: ENSMUSG00000020689
1098:positive regulation of protein phosphorylation
5847:
5390:
4906:
2869:
2658:
1088:apolipoprotein A-I-mediated signaling pathway
8:
2368:"Integrin alphaIIbbeta3 and its antagonism"
1743:GRCh38: Ensembl release 89: ENSG00000259207
1208:substrate adhesion-dependent cell spreading
5854:
5840:
5563:
5397:
5383:
5375:
5259:
4934:
4913:
4899:
4891:
2876:
2862:
2854:
2665:
2651:
2643:
2294:Annals of the New York Academy of Sciences
1308:
828:
602:
501:
398:
76:
5222:Plasminogen activator inhibitor-2 (PAI-2)
5217:Plasminogen activator inhibitor-1 (PAI-1)
2893:list of human clusters of differentiation
2600:at the U.S. National Library of Medicine
2572:
2383:
2242:
2201:
2160:
2119:
2035:
2018:Chung J, Gao AG, Frazier WA (June 1997).
1994:
1945:
1882:
1841:
1047:alphav-beta3 integrin-IGF-1-IGF1R complex
957:alphav-beta3 integrin-vitronectin complex
2680:
1730:
27:Mammalian protein found in Homo sapiens
5015:High-molecular-weight kininogen (HMWK)
1213:negative regulation of lipid transport
1128:angiogenesis involved in wound healing
1052:alphav-beta3 integrin-PKCalpha complex
31:
2553:The Journal of Clinical Investigation
2512:Journal of Thrombosis and Haemostasis
1871:Journal of Thrombosis and Haemostasis
1822:The Journal of Clinical Investigation
1248:activation of protein kinase activity
987:integral component of plasma membrane
566:
527:
522:
465:
424:
419:
7:
5804:
5802:
1203:negative regulation of lipid storage
916:insulin-like growth factor I binding
866:protein disulfide isomerase activity
734:endothelial cell of lymphatic vessel
5300:Thrombin–antithrombin complex (TAT)
2231:The Journal of Biological Chemistry
2190:The Journal of Biological Chemistry
2149:The Journal of Biological Chemistry
2024:The Journal of Biological Chemistry
1198:integrin-mediated signaling pathway
1057:alphav-beta3 integrin-HMGB1 complex
5826:. You can help Knowledge (XXG) by
5792:cell surface receptor deficiencies
5207:Tissue plasminogen activator (tPA)
5164:Protein S (cofactor for protein C)
2385:10.1161/01.ATV.0000066686.46338.F1
2314:10.1111/j.1749-6632.2001.tb03521.x
1540:
1519:
1493:
1472:
1448:
1429:
1403:
1384:
1358:
1339:
1278:regulation of protein localization
1258:cell adhesion mediated by integrin
784:
702:
640:
619:
25:
1669:cell-surface-mediated signaling.
1637:that in humans is encoded by the
1148:extracellular matrix organization
5806:
2833:
2818:
2803:
2788:
2773:
2758:
2743:
2728:
2713:
2698:
2683:
2524:10.1111/j.1538-7836.2005.01429.x
1193:cell-substrate junction assembly
911:fibroblast growth factor binding
802:
795:
788:
550:
543:
537:
514:
449:
442:
436:
411:
40:
5295:Prothrombin fragment 1+2 (F1+2)
4955:Platelet membrane glycoproteins
1188:mesodermal cell differentiation
1012:platelet alpha granule membrane
5883:Human chromosome 17 gene stubs
5159:Protein C (inhibits FV, FVIII)
2437:10.1016/j.thromres.2003.11.010
1283:regulation of serotonin uptake
1123:heterotypic cell-cell adhesion
947:integral component of membrane
896:cell adhesion molecule binding
813:More reference expression data
768:More reference expression data
1:
2454:Current Pharmaceutical Design
2073:10.1016/S0049-3848(01)00405-4
1228:regulation of bone resorption
1017:integrin alphav-beta3 complex
535:
434:
5873:Genes on human chromosome 17
5652:Leukocyte-adhesion receptor:
2547:Bennett JS (December 2005).
1153:smooth muscle cell migration
1103:regulation of cell migration
861:extracellular matrix binding
5711:Very late antigen receptor:
5035:Factor XII (Hageman factor)
4949:von Willebrand factor (vWF)
2889:clusters of differentiation
2483:Current Medicinal Chemistry
2100:The Journal of Cell Biology
1975:The Journal of Cell Biology
672:right lobe of thyroid gland
5899:
5801:
5355:-antiplasmin complex (PAP)
5070:Factor III (tissue factor)
2635:gene details page in the
2339:Thrombosis and Haemostasis
2273:Thrombosis and Haemostasis
1650:cluster of differentiation
742:superior surface of tongue
676:left lobe of thyroid gland
5787:
2678:
1934:Human Reproduction Update
1799:"Mouse PubMed Reference:"
1781:"Human PubMed Reference:"
1613:
1608:
1604:
1597:
1581:
1575:Chr 11: 104.5 – 104.56 Mb
1562:
1547:
1526:
1515:
1500:
1479:
1468:
1455:
1451:
1436:
1432:
1423:
1410:
1406:
1391:
1387:
1378:
1365:
1361:
1346:
1342:
1333:
1318:
1311:
1307:
1291:
886:identical protein binding
831:
827:
810:
787:
778:
765:
714:
705:
668:Descending thoracic aorta
652:
643:
613:
605:
601:
584:
571:
534:
513:
504:
500:
483:
470:
433:
410:
401:
397:
352:
349:
339:
332:
327:
84:
79:
62:
57:
52:
48:
39:
34:
5277:β-Thromboglobulin (β-TG)
2602:Medical Subject Headings
2495:10.2174/0929867053363522
2466:10.2174/1381612043384682
2162:10.1074/jbc.274.40.28575
2037:10.1074/jbc.272.23.14740
1568:Chr 17: 47.25 – 47.31 Mb
1268:apoptotic cell clearance
921:C-X3-C chemokine binding
680:tendon of biceps brachii
5272:Platelet factor 4 (PF4)
5169:Protein Z (inhibits FX)
5103:Prothrombin (factor II)
2610:Info with links in the
1689:CD61 has been shown to
1168:cell-substrate adhesion
856:virus receptor activity
5328:Fibrinopeptide B (FpB)
5323:Fibrinopeptide A (FpA)
4995:Glycoprotein VI (GPVI)
4960:Glycoprotein Ib (GPIb)
2612:Cell Migration Gateway
2351:10.1055/s-0037-1612971
2244:10.1074/jbc.272.8.4651
2203:10.1074/jbc.M111996200
1660:Structure and function
1138:platelet degranulation
1027:lamellipodium membrane
568:11 E1|11 67.84 cM
5763:Vitronectin receptor:
5626:Fibronectin receptor:
5579:Glycoprotein IIb/IIIa
5567:Cytoadhesin receptor:
5146:Anticoagulant factors
5113:Fibrinogen (factor I)
5108:Thrombin (factor IIa)
4980:Glycoprotein IIb/IIIa
4974:Glycoprotein IX (GP9)
4941:(platelet activation)
2403:Italian Heart Journal
2112:10.1083/jcb.131.3.807
1987:10.1083/jcb.200109079
1947:10.1093/humupd/dmr013
1719:Glycoprotein IIb/IIIa
1673:Role in endometriosis
1062:glutamatergic synapse
1022:extracellular exosome
692:right coronary artery
529:Chromosome 11 (mouse)
427:Chromosome 17 (human)
5754:Integrin alpha6beta1
5728:Integrin alpha3beta1
5723:Integrin alpha2beta1
5718:Integrin alpha1beta1
5691:Integrin alphaXbeta2
5675:Macrophage-1 antigen
5643:Integrin alpha5beta1
5638:Integrin alpha4beta1
5633:Integrin alpha2beta1
5606:Macrophage-1 antigen
5599:Fibrinogen receptor:
5574:Integrin alpha6beta4
5333:Fibrin monomers (FM)
5189:Fibrinolytic factors
5007:(contact activation)
2629:genome location and
1233:platelet aggregation
1218:cell-matrix adhesion
1037:microvillus membrane
80:List of PDB id codes
53:Available structures
5287:Thrombin generation
5264:Platelet activation
5255:Coagulation markers
4930:Coagulation factors
4922:Coagulation cascade
2637:UCSC Genome Browser
2425:Thrombosis Research
2306:2001NYASA.936..340B
2196:(24): 21749–21758.
2155:(40): 28575–28583.
2061:Thrombosis Research
2030:(23): 14740–14746.
1263:platelet activation
1253:leukocyte migration
1108:negative chemotaxis
1042:filopodium membrane
906:coreceptor activity
851:fibronectin binding
5814:This article on a
5127:Fibrin (factor Ia)
4939:Primary hemostasis
2617:2014-12-11 at the
1413:ENSMUSG00000020689
1076:Biological process
940:Cellular component
931:fibrinogen binding
901:neuregulin binding
839:Molecular function
5835:
5834:
5799:
5798:
5783:
5782:
5372:
5371:
5368:
5367:
5315:Fibrin generation
5140:
5139:
5060:Extrinsic pathway
5005:Intrinsic pathway
4888:
4887:
2851:
2850:
2559:(12): 3363–3369.
2460:(14): 1567–1576.
1884:10.1111/jth.12045
1834:10.1172/JCI113548
1624:
1623:
1620:
1619:
1593:
1592:
1558:
1557:
1537:
1536:
1511:
1510:
1490:
1489:
1464:
1463:
1445:
1444:
1419:
1418:
1400:
1399:
1374:
1373:
1355:
1354:
1303:
1302:
1143:blood coagulation
823:
822:
819:
818:
774:
773:
761:
760:
699:
698:
597:
596:
496:
495:
391:ITGB3 - orthologs
323:
322:
319:
318:
63:Ortholog search:
16:(Redirected from
5890:
5856:
5849:
5842:
5810:
5803:
5564:
5399:
5392:
5385:
5376:
5260:
4935:
4915:
4908:
4901:
4892:
2878:
2871:
2864:
2855:
2837:
2822:
2807:
2792:
2777:
2762:
2747:
2732:
2717:
2702:
2687:
2667:
2660:
2653:
2644:
2586:
2576:
2565:10.1172/JCI26989
2543:
2518:(8): 1752–1762.
2506:
2477:
2448:
2418:
2397:
2387:
2362:
2333:
2288:
2257:
2256:
2246:
2237:(8): 4651–4654.
2222:
2216:
2215:
2205:
2181:
2175:
2174:
2164:
2140:
2134:
2133:
2123:
2091:
2085:
2084:
2056:
2050:
2049:
2039:
2015:
2009:
2008:
1998:
1966:
1960:
1959:
1949:
1925:
1919:
1918:
1911:
1905:
1904:
1886:
1862:
1856:
1855:
1845:
1828:(6): 1993–1998.
1813:
1807:
1806:
1795:
1789:
1788:
1777:
1771:
1761:
1750:
1740:
1606:
1605:
1577:
1570:
1553:
1541:
1532:
1520:
1516:RefSeq (protein)
1506:
1494:
1485:
1473:
1449:
1430:
1404:
1385:
1359:
1340:
1309:
1118:tube development
1007:integrin complex
977:receptor complex
926:integrin binding
871:protease binding
829:
815:
806:
799:
792:
785:
770:
710:
708:Top expressed in
703:
684:popliteal artery
648:
646:Top expressed in
641:
620:
603:
593:
580:
569:
554:
547:
541:
530:
518:
502:
492:
479:
468:
453:
446:
440:
429:
415:
399:
393:
344:
337:
314:
77:
71:
50:
49:
44:
32:
21:
5898:
5897:
5893:
5892:
5891:
5889:
5888:
5887:
5863:
5862:
5861:
5860:
5800:
5795:
5779:
5758:
5706:
5647:
5621:
5594:
5555:
5504:
5408:
5403:
5373:
5364:
5354:
5337:
5309:
5281:
5249:
5239:
5230:
5183:
5136:
5079:
5062:(tissue factor)
5061:
5054:
5006:
4999:
4940:
4924:
4919:
4889:
4884:
4688:
4482:
4231:
3915:
3638:
3298:
2896:
2882:
2852:
2847:
2844:
2838:
2829:
2823:
2814:
2808:
2799:
2793:
2784:
2778:
2769:
2763:
2754:
2748:
2739:
2733:
2724:
2718:
2709:
2703:
2694:
2688:
2674:
2671:
2619:Wayback Machine
2594:
2589:
2546:
2509:
2480:
2451:
2421:
2400:
2365:
2336:
2291:
2270:
2266:
2264:Further reading
2261:
2260:
2224:
2223:
2219:
2183:
2182:
2178:
2142:
2141:
2137:
2093:
2092:
2088:
2058:
2057:
2053:
2017:
2016:
2012:
1968:
1967:
1963:
1927:
1926:
1922:
1913:
1912:
1908:
1864:
1863:
1859:
1815:
1814:
1810:
1797:
1796:
1792:
1779:
1778:
1774:
1762:
1753:
1741:
1732:
1727:
1715:
1687:
1675:
1662:
1627:Integrin beta-3
1615:View/Edit Mouse
1610:View/Edit Human
1573:
1566:
1563:Location (UCSC)
1549:
1528:
1502:
1481:
1394:ENSG00000259207
1287:
1071:
992:ruffle membrane
982:plasma membrane
952:cell projection
935:
881:protein binding
811:
801:
800:
794:
793:
766:
757:
752:
748:
744:
740:
736:
732:
728:
724:
720:
718:ascending aorta
706:
695:
690:
688:tibial arteries
686:
682:
678:
674:
670:
666:
664:ascending aorta
662:
658:
644:
588:
575:
567:
557:
556:
555:
548:
528:
505:Gene location (
487:
474:
466:
456:
455:
454:
447:
425:
402:Gene location (
353:
340:
333:
86:
64:
28:
23:
22:
15:
12:
11:
5:
5896:
5894:
5886:
5885:
5880:
5875:
5865:
5864:
5859:
5858:
5851:
5844:
5836:
5833:
5832:
5811:
5797:
5796:
5788:
5785:
5784:
5781:
5780:
5778:
5777:
5775:Alpha-v beta-5
5772:
5770:Alpha-v beta-3
5766:
5764:
5760:
5759:
5757:
5756:
5751:
5749:Alpha-5 beta-1
5746:
5745:
5744:
5730:
5725:
5720:
5714:
5712:
5708:
5707:
5705:
5704:
5703:
5702:
5688:
5687:
5686:
5672:
5671:
5670:
5655:
5653:
5649:
5648:
5646:
5645:
5640:
5635:
5629:
5627:
5623:
5622:
5620:
5619:
5618:
5617:
5602:
5600:
5596:
5595:
5593:
5592:
5591:
5590:
5576:
5570:
5568:
5561:
5557:
5556:
5554:
5553:
5548:
5543:
5538:
5533:
5528:
5523:
5518:
5512:
5510:
5506:
5505:
5503:
5502:
5497:
5492:
5487:
5482:
5477:
5472:
5467:
5462:
5457:
5452:
5447:
5442:
5437:
5432:
5427:
5422:
5416:
5414:
5410:
5409:
5404:
5402:
5401:
5394:
5387:
5379:
5370:
5369:
5366:
5365:
5363:
5362:
5357:
5352:
5347:
5345:
5339:
5338:
5336:
5335:
5330:
5325:
5319:
5317:
5311:
5310:
5308:
5307:
5302:
5297:
5291:
5289:
5283:
5282:
5280:
5279:
5274:
5268:
5266:
5257:
5251:
5250:
5248:
5247:
5242:
5240:-Macroglobulin
5237:
5233:
5228:
5224:
5219:
5214:
5209:
5204:
5199:
5193:
5191:
5185:
5184:
5182:
5181:
5176:
5171:
5166:
5161:
5156:
5150:
5148:
5142:
5141:
5138:
5137:
5135:
5134:
5129:
5124:
5110:
5105:
5100:
5095:
5089:
5087:
5085:Common pathway
5081:
5080:
5078:
5077:
5072:
5066:
5064:
5056:
5055:
5053:
5052:
5047:
5042:
5037:
5032:
5027:
5022:
5017:
5011:
5009:
5001:
5000:
4998:
4997:
4992:
4986:
4977:
4971:
4966:
4951:
4945:
4943:
4932:
4926:
4925:
4920:
4918:
4917:
4910:
4903:
4895:
4886:
4885:
4883:
4882:
4877:
4872:
4867:
4862:
4857:
4852:
4847:
4842:
4837:
4832:
4827:
4822:
4817:
4812:
4807:
4802:
4797:
4792:
4787:
4782:
4777:
4772:
4767:
4762:
4757:
4752:
4747:
4742:
4737:
4732:
4727:
4722:
4717:
4712:
4707:
4702:
4696:
4694:
4690:
4689:
4687:
4686:
4681:
4676:
4671:
4666:
4661:
4656:
4651:
4646:
4641:
4636:
4631:
4626:
4621:
4616:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4576:
4571:
4566:
4561:
4556:
4551:
4546:
4541:
4536:
4531:
4526:
4521:
4516:
4511:
4506:
4501:
4496:
4490:
4488:
4484:
4483:
4481:
4480:
4475:
4466:
4461:
4456:
4451:
4446:
4441:
4436:
4431:
4426:
4421:
4420:
4419:
4414:
4404:
4399:
4394:
4389:
4384:
4379:
4374:
4369:
4364:
4359:
4354:
4349:
4344:
4339:
4333:
4324:
4319:
4318:
4317:
4312:
4302:
4297:
4296:
4295:
4290:
4280:
4275:
4270:
4265:
4260:
4255:
4250:
4245:
4239:
4237:
4233:
4232:
4230:
4229:
4224:
4219:
4214:
4209:
4204:
4199:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4159:
4154:
4149:
4144:
4143:
4142:
4137:
4127:
4122:
4117:
4112:
4111:
4110:
4105:
4100:
4090:
4085:
4080:
4075:
4070:
4069:
4068:
4063:
4053:
4048:
4043:
4038:
4033:
4028:
4023:
4022:
4021:
4016:
4006:
4000:
3995:
3990:
3985:
3976:
3971:
3970:
3969:
3964:
3959:
3949:
3944:
3939:
3934:
3929:
3923:
3921:
3917:
3916:
3914:
3913:
3908:
3903:
3898:
3893:
3888:
3883:
3878:
3873:
3868:
3863:
3858:
3853:
3848:
3843:
3838:
3833:
3828:
3823:
3818:
3813:
3808:
3803:
3798:
3793:
3788:
3787:
3786:
3781:
3771:
3770:
3769:
3764:
3754:
3749:
3744:
3739:
3734:
3729:
3724:
3719:
3714:
3709:
3704:
3699:
3694:
3693:
3692:
3687:
3677:
3672:
3667:
3662:
3657:
3652:
3646:
3644:
3640:
3639:
3637:
3636:
3631:
3626:
3621:
3616:
3611:
3606:
3601:
3596:
3587:
3582:
3577:
3572:
3567:
3562:
3561:
3560:
3555:
3550:
3545:
3540:
3535:
3525:
3520:
3515:
3510:
3505:
3500:
3499:
3498:
3493:
3483:
3478:
3473:
3468:
3463:
3458:
3453:
3448:
3443:
3442:
3441:
3436:
3431:
3426:
3421:
3416:
3406:
3405:
3404:
3399:
3394:
3384:
3379:
3378:
3377:
3372:
3367:
3357:
3352:
3347:
3342:
3337:
3332:
3327:
3322:
3317:
3312:
3306:
3304:
3300:
3299:
3297:
3296:
3291:
3290:
3289:
3284:
3279:
3274:
3269:
3264:
3254:
3249:
3244:
3239:
3234:
3229:
3224:
3223:
3222:
3217:
3212:
3207:
3197:
3192:
3187:
3182:
3177:
3172:
3167:
3162:
3157:
3152:
3151:
3150:
3145:
3135:
3130:
3125:
3120:
3115:
3110:
3105:
3100:
3095:
3090:
3085:
3080:
3075:
3070:
3065:
3064:
3063:
3058:
3048:
3043:
3038:
3033:
3032:
3031:
3026:
3021:
3016:
3006:
3001:
2996:
2995:
2994:
2984:
2979:
2974:
2969:
2964:
2963:
2962:
2957:
2952:
2942:
2937:
2936:
2935:
2930:
2925:
2920:
2915:
2904:
2902:
2898:
2897:
2883:
2881:
2880:
2873:
2866:
2858:
2849:
2848:
2846:
2845:
2839:
2832:
2830:
2824:
2817:
2815:
2809:
2802:
2800:
2794:
2787:
2785:
2779:
2772:
2770:
2764:
2757:
2755:
2749:
2742:
2740:
2734:
2727:
2725:
2719:
2712:
2710:
2704:
2697:
2695:
2689:
2682:
2679:
2676:
2675:
2672:
2670:
2669:
2662:
2655:
2647:
2641:
2640:
2621:
2605:
2593:
2592:External links
2590:
2588:
2587:
2544:
2507:
2478:
2449:
2431:(4): 209–216.
2419:
2398:
2378:(6): 945–952.
2363:
2345:(2): 187–193.
2334:
2300:(1): 340–354.
2289:
2279:(4): 492–502.
2267:
2265:
2262:
2259:
2258:
2217:
2176:
2135:
2106:(3): 807–816.
2086:
2051:
2010:
1981:(1): 149–160.
1961:
1940:(5): 637–653.
1920:
1906:
1857:
1808:
1790:
1772:
1751:
1729:
1728:
1726:
1723:
1722:
1721:
1714:
1711:
1686:
1683:
1674:
1671:
1661:
1658:
1622:
1621:
1618:
1617:
1612:
1602:
1601:
1595:
1594:
1591:
1590:
1588:
1586:
1579:
1578:
1571:
1564:
1560:
1559:
1556:
1555:
1545:
1544:
1538:
1535:
1534:
1524:
1523:
1517:
1513:
1512:
1509:
1508:
1498:
1497:
1491:
1488:
1487:
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1476:
1470:
1466:
1465:
1462:
1461:
1453:
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1446:
1443:
1442:
1434:
1433:
1427:
1421:
1420:
1417:
1416:
1408:
1407:
1401:
1398:
1397:
1389:
1388:
1382:
1376:
1375:
1372:
1371:
1363:
1362:
1356:
1353:
1352:
1344:
1343:
1337:
1331:
1330:
1325:
1320:
1316:
1315:
1305:
1304:
1301:
1300:
1289:
1288:
1286:
1285:
1280:
1275:
1270:
1265:
1260:
1255:
1250:
1245:
1240:
1238:cell migration
1235:
1230:
1225:
1220:
1215:
1210:
1205:
1200:
1195:
1190:
1185:
1180:
1175:
1170:
1165:
1160:
1155:
1150:
1145:
1140:
1135:
1130:
1125:
1120:
1115:
1110:
1105:
1100:
1095:
1090:
1085:
1079:
1077:
1073:
1072:
1070:
1069:
1064:
1059:
1054:
1049:
1044:
1039:
1034:
1029:
1024:
1019:
1014:
1009:
1004:
999:
994:
989:
984:
979:
974:
969:
967:focal adhesion
964:
959:
954:
949:
943:
941:
937:
936:
934:
933:
928:
923:
918:
913:
908:
903:
898:
893:
891:enzyme binding
888:
883:
878:
873:
868:
863:
858:
853:
848:
842:
840:
836:
835:
825:
824:
821:
820:
817:
816:
808:
807:
782:
776:
775:
772:
771:
763:
762:
759:
758:
756:
755:
751:
747:
743:
739:
735:
731:
727:
723:
719:
715:
712:
711:
700:
697:
696:
694:
693:
689:
685:
681:
677:
673:
669:
665:
661:
660:thoracic aorta
657:
653:
650:
649:
637:
636:
628:
617:
611:
610:
607:RNA expression
599:
598:
595:
594:
586:
582:
581:
573:
570:
565:
559:
558:
549:
542:
536:
532:
531:
526:
520:
519:
511:
510:
498:
497:
494:
493:
485:
481:
480:
472:
469:
464:
458:
457:
448:
441:
435:
431:
430:
423:
417:
416:
408:
407:
395:
394:
351:
347:
346:
338:
330:
329:
325:
324:
321:
320:
317:
316:
82:
81:
73:
72:
61:
55:
54:
46:
45:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
5895:
5884:
5881:
5879:
5876:
5874:
5871:
5870:
5868:
5857:
5852:
5850:
5845:
5843:
5838:
5837:
5831:
5829:
5825:
5821:
5820:chromosome 17
5817:
5812:
5809:
5805:
5794:
5793:
5786:
5776:
5773:
5771:
5768:
5767:
5765:
5761:
5755:
5752:
5750:
5747:
5743:
5739:
5736:
5735:
5734:
5731:
5729:
5726:
5724:
5721:
5719:
5716:
5715:
5713:
5709:
5701:
5697:
5694:
5693:
5692:
5689:
5685:
5681:
5678:
5677:
5676:
5673:
5669:
5665:
5662:
5661:
5660:
5657:
5656:
5654:
5650:
5644:
5641:
5639:
5636:
5634:
5631:
5630:
5628:
5624:
5616:
5612:
5609:
5608:
5607:
5604:
5603:
5601:
5597:
5589:
5585:
5582:
5581:
5580:
5577:
5575:
5572:
5571:
5569:
5565:
5562:
5558:
5552:
5549:
5547:
5544:
5542:
5539:
5537:
5534:
5532:
5529:
5527:
5524:
5522:
5519:
5517:
5514:
5513:
5511:
5507:
5501:
5498:
5496:
5493:
5491:
5488:
5486:
5483:
5481:
5478:
5476:
5473:
5471:
5468:
5466:
5463:
5461:
5458:
5456:
5453:
5451:
5448:
5446:
5443:
5441:
5438:
5436:
5433:
5431:
5428:
5426:
5423:
5421:
5418:
5417:
5415:
5411:
5407:
5400:
5395:
5393:
5388:
5386:
5381:
5380:
5377:
5361:
5358:
5356:
5349:
5348:
5346:
5344:
5340:
5334:
5331:
5329:
5326:
5324:
5321:
5320:
5318:
5316:
5312:
5306:
5303:
5301:
5298:
5296:
5293:
5292:
5290:
5288:
5284:
5278:
5275:
5273:
5270:
5269:
5267:
5265:
5261:
5258:
5256:
5252:
5246:
5243:
5241:
5234:
5232:
5225:
5223:
5220:
5218:
5215:
5213:
5210:
5208:
5205:
5203:
5200:
5198:
5195:
5194:
5192:
5190:
5186:
5180:
5177:
5175:
5172:
5170:
5167:
5165:
5162:
5160:
5157:
5155:
5152:
5151:
5149:
5147:
5143:
5133:
5130:
5128:
5125:
5122:
5118:
5114:
5111:
5109:
5106:
5104:
5101:
5099:
5096:
5094:
5091:
5090:
5088:
5086:
5082:
5076:
5073:
5071:
5068:
5067:
5065:
5063:
5057:
5051:
5048:
5046:
5043:
5041:
5038:
5036:
5033:
5031:
5028:
5026:
5025:Prekallikrein
5023:
5021:
5018:
5016:
5013:
5012:
5010:
5008:
5002:
4996:
4993:
4990:
4987:
4985:
4981:
4978:
4975:
4972:
4970:
4967:
4965:
4961:
4958:
4956:
4952:
4950:
4947:
4946:
4944:
4942:
4936:
4933:
4931:
4927:
4923:
4916:
4911:
4909:
4904:
4902:
4897:
4896:
4893:
4881:
4878:
4876:
4873:
4871:
4868:
4866:
4863:
4861:
4858:
4856:
4853:
4851:
4848:
4846:
4843:
4841:
4838:
4836:
4833:
4831:
4828:
4826:
4823:
4821:
4818:
4816:
4813:
4811:
4808:
4806:
4803:
4801:
4798:
4796:
4793:
4791:
4788:
4786:
4783:
4781:
4778:
4776:
4773:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4736:
4733:
4731:
4728:
4726:
4723:
4721:
4718:
4716:
4713:
4711:
4708:
4706:
4703:
4701:
4698:
4697:
4695:
4691:
4685:
4682:
4680:
4677:
4675:
4672:
4670:
4667:
4665:
4662:
4660:
4657:
4655:
4652:
4650:
4647:
4645:
4642:
4640:
4637:
4635:
4632:
4630:
4627:
4625:
4622:
4620:
4617:
4615:
4612:
4610:
4607:
4605:
4602:
4600:
4597:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4577:
4575:
4572:
4570:
4567:
4565:
4562:
4560:
4557:
4555:
4552:
4550:
4547:
4545:
4542:
4540:
4537:
4535:
4532:
4530:
4527:
4525:
4522:
4520:
4517:
4515:
4512:
4510:
4507:
4505:
4502:
4500:
4497:
4495:
4492:
4491:
4489:
4485:
4479:
4476:
4474:
4470:
4467:
4465:
4462:
4460:
4457:
4455:
4452:
4450:
4447:
4445:
4442:
4440:
4437:
4435:
4432:
4430:
4427:
4425:
4422:
4418:
4415:
4413:
4410:
4409:
4408:
4405:
4403:
4400:
4398:
4395:
4393:
4390:
4388:
4385:
4383:
4380:
4378:
4375:
4373:
4370:
4368:
4365:
4363:
4360:
4358:
4355:
4353:
4350:
4348:
4345:
4343:
4340:
4337:
4334:
4332:
4328:
4325:
4323:
4320:
4316:
4313:
4311:
4308:
4307:
4306:
4303:
4301:
4298:
4294:
4291:
4289:
4286:
4285:
4284:
4281:
4279:
4276:
4274:
4271:
4269:
4266:
4264:
4261:
4259:
4256:
4254:
4251:
4249:
4246:
4244:
4241:
4240:
4238:
4234:
4228:
4225:
4223:
4220:
4218:
4215:
4213:
4210:
4208:
4205:
4203:
4200:
4198:
4195:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4160:
4158:
4155:
4153:
4150:
4148:
4145:
4141:
4138:
4136:
4133:
4132:
4131:
4128:
4126:
4123:
4121:
4118:
4116:
4113:
4109:
4106:
4104:
4101:
4099:
4096:
4095:
4094:
4091:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4067:
4064:
4062:
4059:
4058:
4057:
4054:
4052:
4049:
4047:
4044:
4042:
4039:
4037:
4034:
4032:
4029:
4027:
4024:
4020:
4017:
4015:
4012:
4011:
4010:
4007:
4004:
4001:
3999:
3996:
3994:
3991:
3989:
3986:
3984:
3980:
3977:
3975:
3972:
3968:
3965:
3963:
3960:
3958:
3955:
3954:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3924:
3922:
3918:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3892:
3889:
3887:
3884:
3882:
3879:
3877:
3874:
3872:
3869:
3867:
3864:
3862:
3859:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3817:
3814:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3785:
3782:
3780:
3777:
3776:
3775:
3772:
3768:
3765:
3763:
3760:
3759:
3758:
3755:
3753:
3750:
3748:
3745:
3743:
3740:
3738:
3735:
3733:
3730:
3728:
3725:
3723:
3720:
3718:
3715:
3713:
3710:
3708:
3705:
3703:
3700:
3698:
3695:
3691:
3688:
3686:
3683:
3682:
3681:
3678:
3676:
3673:
3671:
3668:
3666:
3663:
3661:
3658:
3656:
3653:
3651:
3648:
3647:
3645:
3641:
3635:
3632:
3630:
3627:
3625:
3622:
3620:
3617:
3615:
3612:
3610:
3607:
3605:
3602:
3600:
3597:
3595:
3591:
3588:
3586:
3583:
3581:
3578:
3576:
3573:
3571:
3568:
3566:
3563:
3559:
3556:
3554:
3551:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3530:
3529:
3526:
3524:
3521:
3519:
3516:
3514:
3511:
3509:
3506:
3504:
3501:
3497:
3494:
3492:
3489:
3488:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3454:
3452:
3449:
3447:
3444:
3440:
3437:
3435:
3432:
3430:
3427:
3425:
3422:
3420:
3417:
3415:
3412:
3411:
3410:
3407:
3403:
3400:
3398:
3395:
3393:
3390:
3389:
3388:
3385:
3383:
3380:
3376:
3373:
3371:
3368:
3366:
3363:
3362:
3361:
3358:
3356:
3353:
3351:
3348:
3346:
3343:
3341:
3338:
3336:
3333:
3331:
3328:
3326:
3323:
3321:
3318:
3316:
3313:
3311:
3308:
3307:
3305:
3301:
3295:
3292:
3288:
3285:
3283:
3280:
3278:
3275:
3273:
3270:
3268:
3265:
3263:
3260:
3259:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3221:
3218:
3216:
3213:
3211:
3208:
3206:
3203:
3202:
3201:
3198:
3196:
3193:
3191:
3188:
3186:
3183:
3181:
3178:
3176:
3173:
3171:
3168:
3166:
3163:
3161:
3158:
3156:
3153:
3149:
3146:
3144:
3141:
3140:
3139:
3136:
3134:
3131:
3129:
3126:
3124:
3121:
3119:
3116:
3114:
3111:
3109:
3106:
3104:
3101:
3099:
3096:
3094:
3091:
3089:
3086:
3084:
3081:
3079:
3076:
3074:
3071:
3069:
3066:
3062:
3059:
3057:
3054:
3053:
3052:
3049:
3047:
3044:
3042:
3039:
3037:
3034:
3030:
3027:
3025:
3022:
3020:
3017:
3015:
3012:
3011:
3010:
3007:
3005:
3002:
3000:
2997:
2993:
2990:
2989:
2988:
2985:
2983:
2980:
2978:
2975:
2973:
2970:
2968:
2965:
2961:
2958:
2956:
2953:
2951:
2948:
2947:
2946:
2943:
2941:
2938:
2934:
2931:
2929:
2926:
2924:
2921:
2919:
2916:
2914:
2911:
2910:
2909:
2906:
2905:
2903:
2899:
2894:
2890:
2886:
2879:
2874:
2872:
2867:
2865:
2860:
2859:
2856:
2842:
2836:
2831:
2827:
2821:
2816:
2812:
2806:
2801:
2797:
2791:
2786:
2782:
2776:
2771:
2767:
2761:
2756:
2752:
2746:
2741:
2737:
2731:
2726:
2722:
2716:
2711:
2707:
2701:
2696:
2692:
2686:
2681:
2677:
2668:
2663:
2661:
2656:
2654:
2649:
2648:
2645:
2638:
2634:
2633:
2628:
2627:
2622:
2620:
2616:
2613:
2609:
2606:
2603:
2599:
2598:CD61+Antigens
2596:
2595:
2591:
2584:
2580:
2575:
2570:
2566:
2562:
2558:
2554:
2550:
2545:
2541:
2537:
2533:
2529:
2525:
2521:
2517:
2513:
2508:
2504:
2500:
2496:
2492:
2488:
2484:
2479:
2475:
2471:
2467:
2463:
2459:
2455:
2450:
2446:
2442:
2438:
2434:
2430:
2426:
2420:
2416:
2412:
2408:
2404:
2399:
2395:
2391:
2386:
2381:
2377:
2373:
2369:
2364:
2360:
2356:
2352:
2348:
2344:
2340:
2335:
2331:
2327:
2323:
2319:
2315:
2311:
2307:
2303:
2299:
2295:
2290:
2286:
2282:
2278:
2274:
2269:
2268:
2263:
2254:
2250:
2245:
2240:
2236:
2232:
2228:
2221:
2218:
2213:
2209:
2204:
2199:
2195:
2191:
2187:
2180:
2177:
2172:
2168:
2163:
2158:
2154:
2150:
2146:
2139:
2136:
2131:
2127:
2122:
2117:
2113:
2109:
2105:
2101:
2097:
2090:
2087:
2082:
2078:
2074:
2070:
2066:
2062:
2055:
2052:
2047:
2043:
2038:
2033:
2029:
2025:
2021:
2014:
2011:
2006:
2002:
1997:
1992:
1988:
1984:
1980:
1976:
1972:
1965:
1962:
1957:
1953:
1948:
1943:
1939:
1935:
1931:
1924:
1921:
1916:
1910:
1907:
1902:
1898:
1894:
1890:
1885:
1880:
1876:
1872:
1868:
1861:
1858:
1853:
1849:
1844:
1839:
1835:
1831:
1827:
1823:
1819:
1812:
1809:
1804:
1800:
1794:
1791:
1786:
1782:
1776:
1773:
1769:
1765:
1760:
1758:
1756:
1752:
1748:
1744:
1739:
1737:
1735:
1731:
1724:
1720:
1717:
1716:
1712:
1710:
1708:
1704:
1700:
1696:
1692:
1684:
1682:
1680:
1679:endometriosis
1672:
1670:
1667:
1659:
1657:
1655:
1651:
1647:
1643:
1640:
1636:
1632:
1628:
1616:
1611:
1607:
1603:
1600:
1596:
1589:
1587:
1584:
1580:
1576:
1572:
1569:
1565:
1561:
1554:
1552:
1546:
1542:
1539:
1533:
1531:
1525:
1521:
1518:
1514:
1507:
1505:
1499:
1495:
1492:
1486:
1484:
1478:
1474:
1471:
1469:RefSeq (mRNA)
1467:
1460:
1459:
1454:
1450:
1447:
1441:
1440:
1435:
1431:
1428:
1426:
1422:
1415:
1414:
1409:
1405:
1402:
1396:
1395:
1390:
1386:
1383:
1381:
1377:
1370:
1369:
1364:
1360:
1357:
1351:
1350:
1345:
1341:
1338:
1336:
1332:
1329:
1326:
1324:
1321:
1317:
1314:
1310:
1306:
1299:
1295:
1290:
1284:
1281:
1279:
1276:
1274:
1271:
1269:
1266:
1264:
1261:
1259:
1256:
1254:
1251:
1249:
1246:
1244:
1241:
1239:
1236:
1234:
1231:
1229:
1226:
1224:
1223:viral process
1221:
1219:
1216:
1214:
1211:
1209:
1206:
1204:
1201:
1199:
1196:
1194:
1191:
1189:
1186:
1184:
1181:
1179:
1178:cell adhesion
1176:
1174:
1171:
1169:
1166:
1164:
1161:
1159:
1156:
1154:
1151:
1149:
1146:
1144:
1141:
1139:
1136:
1134:
1133:wound healing
1131:
1129:
1126:
1124:
1121:
1119:
1116:
1114:
1111:
1109:
1106:
1104:
1101:
1099:
1096:
1094:
1091:
1089:
1086:
1084:
1081:
1080:
1078:
1075:
1074:
1068:
1065:
1063:
1060:
1058:
1055:
1053:
1050:
1048:
1045:
1043:
1040:
1038:
1035:
1033:
1030:
1028:
1025:
1023:
1020:
1018:
1015:
1013:
1010:
1008:
1005:
1003:
1002:cell junction
1000:
998:
995:
993:
990:
988:
985:
983:
980:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
948:
945:
944:
942:
939:
938:
932:
929:
927:
924:
922:
919:
917:
914:
912:
909:
907:
904:
902:
899:
897:
894:
892:
889:
887:
884:
882:
879:
877:
874:
872:
869:
867:
864:
862:
859:
857:
854:
852:
849:
847:
844:
843:
841:
838:
837:
834:
833:Gene ontology
830:
826:
814:
809:
805:
798:
791:
786:
783:
781:
777:
769:
764:
753:
750:body of femur
749:
745:
741:
737:
733:
729:
725:
721:
717:
716:
713:
709:
704:
701:
691:
687:
683:
679:
675:
671:
667:
663:
659:
655:
654:
651:
647:
642:
639:
638:
635:
633:
629:
627:
626:
622:
621:
618:
616:
612:
608:
604:
600:
592:
587:
583:
579:
574:
564:
560:
553:
546:
540:
533:
525:
521:
517:
512:
508:
503:
499:
491:
486:
482:
478:
473:
463:
459:
452:
445:
439:
432:
428:
422:
418:
414:
409:
405:
400:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
348:
343:
336:
331:
326:
315:
313:
309:
305:
301:
297:
293:
289:
285:
281:
277:
273:
269:
265:
261:
257:
253:
249:
245:
241:
237:
233:
229:
225:
221:
217:
213:
209:
205:
201:
197:
193:
189:
185:
181:
177:
173:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
129:
125:
121:
117:
113:
109:
105:
101:
97:
93:
89:
83:
78:
75:
74:
70:
67:
60:
56:
51:
47:
43:
38:
33:
30:
19:
5828:expanding it
5813:
5789:
5360:D-Dimer (DD)
5343:Fibrinolysis
5231:-Antiplasmin
4953:
4406:
4326:
4304:
4282:
4129:
4092:
4055:
4008:
3978:
3951:
3773:
3679:
3527:
3256:
3008:
2840:
2825:
2810:
2795:
2780:
2765:
2750:
2735:
2720:
2705:
2690:
2631:
2625:
2556:
2552:
2515:
2511:
2489:(1): 51–70.
2486:
2482:
2457:
2453:
2428:
2424:
2409:(1): 17–22.
2406:
2402:
2375:
2371:
2342:
2338:
2297:
2293:
2276:
2272:
2234:
2230:
2220:
2193:
2189:
2179:
2152:
2148:
2138:
2103:
2099:
2089:
2067:(1): 63–70.
2064:
2060:
2054:
2027:
2023:
2013:
1978:
1974:
1964:
1937:
1933:
1923:
1909:
1874:
1870:
1860:
1825:
1821:
1811:
1802:
1793:
1784:
1775:
1688:
1685:Interactions
1676:
1663:
1654:thrombocytes
1645:
1638:
1630:
1626:
1625:
1548:
1527:
1501:
1480:
1456:
1437:
1411:
1392:
1366:
1347:
1327:
1322:
997:cell surface
722:aortic valve
630:
623:
589:104,561,302
576:104,498,826
350:External IDs
85:
29:
5197:Plasminogen
5132:Factor XIII
5050:Factor VIII
2673:PDB gallery
1877:(1): 2–16.
1163:cell growth
738:granulocyte
488:47,313,743
475:47,253,827
328:Identifiers
5867:Categories
5075:Factor VII
5030:Kallikrein
5020:Bradykinin
2891:(see also
1770:, May 2017
1749:, May 2017
1725:References
972:melanosome
634:(ortholog)
371:HomoloGene
5878:Integrins
5818:on human
5790:see also
5406:Integrins
5351:Plasmin-α
5212:Urokinase
5045:Factor IX
5040:Factor XI
1901:206157070
1666:Integrins
1652:found on
1551:NP_058060
1530:NP_000203
1504:NM_016780
1483:NM_000212
1313:Orthologs
379:GeneCards
5098:Factor V
5093:Factor X
2885:Proteins
2615:Archived
2583:16322781
2540:42666713
2532:16102042
2503:15638730
2474:15134555
2445:14987913
2415:12690916
2394:12637342
2359:11858476
2330:25431334
2322:11460491
2212:11932255
2171:10497223
2081:11864709
2005:11927607
1956:21672902
1893:23106920
1766:–
1745:–
1713:See also
1691:interact
1629:(β3) or
1599:Wikidata
1292:Sources:
962:membrane
656:monocyte
467:17q21.32
5202:Plasmin
4693:301–350
4487:251–300
4439:CD240CE
4236:201–250
3920:151–200
3643:101–150
2574:1297263
2302:Bibcode
2285:7878622
2253:9030514
2130:7593198
2121:2120613
2046:9169439
1996:2173263
1852:2454952
1768:Ensembl
1747:Ensembl
1699:ITGB3BP
1635:protein
1425:UniProt
1380:Ensembl
1319:Species
1298:QuickGO
1067:synapse
1032:nucleus
726:decidua
609:pattern
335:Aliases
5584:ITGA2B
5560:Dimers
4989:GPIIIa
4700:CD300A
4659:CDw293
4444:CD240D
4305:CD213a
4283:CDw210
4248:CD202b
4222:CDw199
4217:CDw198
3871:CD140b
3303:51–100
2623:Human
2604:(MeSH)
2581:
2571:
2538:
2530:
2501:
2472:
2443:
2413:
2392:
2357:
2328:
2320:
2283:
2251:
2210:
2169:
2128:
2118:
2079:
2044:
2003:
1993:
1954:
1899:
1891:
1850:
1843:442653
1840:
1585:search
1583:PubMed
1458:O54890
1439:P05106
1335:Entrez
780:BioGPS
754:zygote
359:173470
5822:is a
5738:CD49d
5733:VLA-4
5696:CD11c
5680:CD11b
5664:CD11a
5659:LFA-1
5611:CD11b
5588:ITGB3
5413:Alpha
4984:GPIIb
4969:GP1BB
4964:GP1BA
4880:CD350
4875:CD349
4870:CD344
4865:CD340
4860:CD339
4855:CD338
4850:CD337
4845:CD336
4840:CD335
4835:CD334
4830:CD333
4825:CD332
4820:CD331
4815:CD329
4810:CD328
4805:CD327
4800:CD326
4795:CD325
4790:CD324
4785:CD322
4780:CD321
4775:CD320
4770:CD318
4765:CD317
4760:CD316
4755:CD315
4750:CD314
4745:CD312
4740:CD309
4735:CD307
4730:CD306
4725:CD305
4720:CD304
4715:CD303
4710:CD302
4705:CD301
4684:CD299
4679:CD298
4674:CD297
4669:CD295
4664:CD294
4654:CD292
4649:CD290
4644:CD289
4639:CD288
4634:CD286
4629:CD284
4624:CD283
4619:CD282
4614:CD281
4609:CD280
4604:CD279
4599:CD278
4594:CD276
4589:CD275
4584:CD274
4579:CD273
4574:CD272
4569:CD271
4564:CD269
4559:CD268
4554:CD267
4549:CD266
4544:CD265
4539:CD264
4534:CD263
4529:CD262
4524:CD261
4519:CD258
4514:CD257
4509:CD256
4504:CD254
4499:CD253
4494:CD252
4478:CD249
4473:CD248
4469:CD247
4464:CD246
4459:CD244
4454:CD243
4449:CD241
4434:CD239
4429:CD238
4424:CD236
4407:CD235
4402:CD234
4397:CD233
4392:CD230
4387:CD229
4382:CD228
4377:CD227
4372:CD226
4367:CD225
4362:CD224
4357:CD223
4352:CD222
4347:CD221
4342:CD220
4327:CD218
4322:CD217
4300:CD212
4278:CD209
4273:CD208
4268:CD207
4263:CD206
4258:CD205
4253:CD204
4243:CD201
4227:CD200
4212:CD197
4207:CD196
4202:CD195
4197:CD194
4192:CD193
4187:CD192
4182:CD191
4177:CD186
4172:CD185
4167:CD184
4162:CD183
4157:CD182
4152:CD181
4147:CD180
4130:CD179
4125:CD178
4120:CD177
4115:CD174
4093:CD172
4088:CD171
4083:CD170
4078:CD169
4073:CD168
4056:CD167
4051:CD166
4046:CD164
4041:CD163
4036:CD162
4031:CD161
4026:CD160
4009:CD159
3979:CD158
3974:CD157
3952:CD156
3947:CD155
3942:CD154
3937:CD153
3932:CD152
3927:CD151
3911:CD150
3906:CD148
3901:CD147
3896:CD146
3891:CD144
3886:CD143
3881:CD142
3876:CD141
3866:CD138
3861:CD137
3856:CD136
3851:CD135
3846:CD134
3841:CD133
3836:CD132
3831:CD131
3826:CD130
3821:CD129
3816:CD127
3811:CD126
3806:CD125
3801:CD124
3796:CD123
3791:CD122
3774:CD121
3757:CD120
3752:CD119
3747:CD118
3742:CD117
3737:CD116
3732:CD115
3727:CD114
3722:CD113
3717:CD112
3712:CD111
3707:CD110
3702:CD109
3697:CD108
3680:CD107
3675:CD106
3670:CD105
3665:CD104
3660:CD103
3655:CD102
3650:CD101
3634:CD100
2632:ITGB3
2626:ITGB3
2608:ITGB3
2536:S2CID
2326:S2CID
1897:S2CID
1693:with
1648:is a
1639:ITGB3
1633:is a
1368:16416
1328:Mouse
1323:Human
1294:Amigo
746:femur
730:blood
632:Mouse
625:Human
572:Start
507:Mouse
471:Start
404:Human
383:ITGB3
375:55444
367:96612
342:ITGB3
35:ITGB3
5824:stub
5816:gene
5742:CD29
5700:CD18
5684:CD18
5668:CD18
5615:CD18
5509:Beta
3629:CD99
3624:CD98
3619:CD97
3614:CD96
3609:CD95
3604:CD94
3599:CD93
3594:CD92
3590:CD91
3585:CD90
3580:CD89
3575:CD88
3570:CD87
3565:CD86
3528:CD85
3523:CD84
3518:CD83
3513:CD82
3508:CD81
3503:CD80
3486:CD79
3481:CD78
3476:CD74
3471:CD73
3466:CD72
3461:CD71
3456:CD70
3451:CD69
3446:CD68
3409:CD66
3387:CD64
3382:CD63
3360:CD62
3355:CD61
3350:CD59
3345:CD58
3340:CD57
3335:CD56
3330:CD55
3325:CD54
3320:CD53
3315:CD52
3310:CD51
3294:CD50
3257:CD49
3252:CD48
3247:CD47
3242:CD46
3237:CD45
3232:CD44
3227:CD43
3200:CD42
3195:CD41
3190:CD40
3185:CD39
3180:CD38
3175:CD37
3170:CD36
3165:CD35
3160:CD34
3155:CD33
3138:CD32
3133:CD31
3128:CD30
3123:CD29
3118:CD28
3113:CD27
3108:CD26
3103:CD25
3098:CD24
3093:CD23
3088:CD22
3083:CD21
3078:CD20
3073:CD19
3068:CD18
3051:CD16
3046:CD15
3041:CD14
3036:CD13
3009:CD11
3004:CD10
2901:1–50
2841:1u8c
2826:1tye
2811:1ty7
2796:1ty6
2781:1ty5
2766:1ty3
2751:1txv
2736:1m8o
2721:1m1x
2706:1l5g
2691:1jv2
2579:PMID
2528:PMID
2499:PMID
2470:PMID
2441:PMID
2411:PMID
2390:PMID
2355:PMID
2318:PMID
2281:PMID
2249:PMID
2208:PMID
2167:PMID
2126:PMID
2077:PMID
2042:PMID
2001:PMID
1952:PMID
1889:PMID
1848:PMID
1707:CIB1
1705:and
1703:TLN1
1695:PTK2
1646:CD61
1642:gene
1631:CD61
1349:3690
615:Bgee
563:Band
524:Chr.
462:Band
421:Chr.
355:OMIM
312:4Z7N
308:4Z7O
304:4Z7Q
300:5HDB
296:4MMZ
292:4MMY
288:4MMX
284:4G1M
280:4G1E
276:4CAK
272:3ZE2
268:3ZE1
264:3ZE0
260:3ZDZ
256:3ZDY
252:3ZDX
248:3T3P
244:3T3M
240:3NIG
236:3NIF
232:3NID
228:3IJE
224:3FCU
220:3FCS
216:2VDR
212:2VDQ
208:2VDP
204:2VDN
200:2VDM
196:2VDL
192:2VDK
188:2VC2
184:2RN0
180:2RMZ
176:2Q6W
172:2MTP
168:2LJF
164:2LJE
160:2LJD
156:2L91
152:2L1C
148:2KV9
144:2KNC
140:2K9J
136:1U8C
132:1TYE
128:1S4X
124:1MK9
120:1MK7
116:1MIZ
112:1M8O
108:1M1X
104:1L5G
100:1KUZ
96:1KUP
92:1JV2
88:4O02
69:RCSB
66:PDBe
18:CD61
5470:A11
5465:A10
5121:FGG
5117:FGA
2999:CD9
2987:CD8
2982:CD7
2977:CD6
2972:CD5
2967:CD4
2945:CD3
2940:CD2
2913:a-c
2908:CD1
2569:PMC
2561:doi
2557:115
2520:doi
2491:doi
2462:doi
2433:doi
2429:112
2380:doi
2347:doi
2310:doi
2298:936
2239:doi
2235:272
2198:doi
2194:277
2157:doi
2153:274
2116:PMC
2108:doi
2104:131
2069:doi
2065:105
2032:doi
2028:272
1991:PMC
1983:doi
1979:157
1942:doi
1879:doi
1838:PMC
1830:doi
1644:.
585:End
484:End
387:OMA
363:MGI
59:PDB
5869::
5551:B8
5546:B7
5541:B6
5536:B5
5531:B4
5526:B3
5521:B2
5516:B1
5500:AX
5495:AV
5490:AM
5485:AL
5480:AE
5475:AD
5460:A9
5455:A8
5450:A7
5445:A6
5440:A5
5435:A4
5430:A3
5425:A2
5420:A1
5119:,
4471:-
3592:-
2933:1E
2928:1D
2923:1B
2918:1A
2887::
2813::
2798::
2783::
2768::
2753::
2577:.
2567:.
2555:.
2551:.
2534:.
2526:.
2514:.
2497:.
2487:12
2485:.
2468:.
2458:10
2456:.
2439:.
2427:.
2405:.
2388:.
2376:23
2374:.
2370:.
2353:.
2343:87
2341:.
2324:.
2316:.
2308:.
2296:.
2277:72
2275:.
2247:.
2233:.
2229:.
2206:.
2192:.
2188:.
2165:.
2151:.
2147:.
2124:.
2114:.
2102:.
2098:.
2075:.
2063:.
2040:.
2026:.
2022:.
1999:.
1989:.
1977:.
1973:.
1950:.
1938:17
1936:.
1932:.
1895:.
1887:.
1875:11
1873:.
1869:.
1846:.
1836:.
1826:81
1824:.
1820:.
1801:.
1783:.
1754:^
1733:^
1709:.
1701:,
1697:,
1656:.
1296:/
591:bp
578:bp
490:bp
477:bp
385:;
381::
377:;
373::
369:;
365::
361:;
357::
310:,
306:,
302:,
298:,
294:,
290:,
286:,
282:,
278:,
274:,
270:,
266:,
262:,
258:,
254:,
250:,
246:,
242:,
238:,
234:,
230:,
226:,
222:,
218:,
214:,
210:,
206:,
202:,
198:,
194:,
190:,
186:,
182:,
178:,
174:,
170:,
166:,
162:,
158:,
154:,
150:,
146:,
142:,
138:,
134:,
130:,
126:,
122:,
118:,
114:,
110:,
106:,
102:,
98:,
94:,
90:,
5855:e
5848:t
5841:v
5830:.
5740:+
5698:+
5682:+
5666:+
5613:+
5586:+
5398:e
5391:t
5384:v
5353:2
5238:2
5236:α
5229:2
5227:α
5123:)
5115:(
4991:)
4982:(
4976:)
4962:(
4957::
4914:e
4907:t
4900:v
4417:b
4412:a
4338:)
4336:b
4331:a
4329:(
4315:2
4310:1
4293:b
4288:a
4140:b
4135:a
4108:g
4103:b
4098:a
4066:b
4061:a
4019:c
4014:a
4005:)
4003:k
3998:i
3993:e
3988:d
3983:a
3981:(
3967:c
3962:b
3957:a
3784:b
3779:a
3767:b
3762:a
3690:b
3685:a
3558:k
3553:j
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