756:(LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
1902:
121:
146:
4078:
1887:
4021:
152:
1901:
1645:
Chang CC, Ciubotariu R, Manavalan JS, Yuan J, Colovai AI, Piazza F, et al. (March 2002). "Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4".
2857:
1996:
825:
ENSG00000275463, ENSG00000131042, ENSG00000276146, ENSG00000277751 GRCh38: Ensembl release 89: ENSG00000274513, ENSG00000275463, ENSG00000131042, ENSG00000276146, ENSG00000277751
1329:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
1025:
Lao K, Zhang R, Dai Y, Luan J, Guo N, Xu X, et al. (July 2021). "Identification of novel AĪ²-LilrB2 inhibitors as potential therapeutic agents for
Alzheimer's disease".
1815:
Papanikolaou NA, Vasilescu ER, Suciu-Foca N (July 2004). "Novel single nucleotide polymorphisms in the human immune inhibitory immunoglobulin-like T cell receptor type 4".
159:
1608:
Young NT, Canavez F, Uhrberg M, Shum BP, Parham P (2001). "Conserved organization of the ILT/LIR gene family within the polymorphic human leukocyte receptor complex".
1684:"Crystal structure of LIR-2 (ILT4) at 1.8 A: differences from LIR-1 (ILT2) in regions implicated in the binding of the Human Cytomegalovirus class I MHC homolog UL18"
910:"Cloning of novel immunoglobulin superfamily receptors expressed on human myeloid and lymphoid cells: structural evidence for new stimulatory and inhibitory pathways"
4119:
1910:: Crystal Structure of LIR-2 (ILT4) at 1.8 : differences from LIR-1 (ILT2) in regions implicated in the binding of the Cytomegalovirus class I MHC homolog UL18
2847:
1886:
2827:
1964:
82:
409:
4062:
3689:
2013:
1989:
3420:
1249:
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
3408:
3186:
753:
4138:
3472:
3467:
3413:
3193:
1974:
1866:
841:
4143:
2926:
2852:
1982:
1729:"Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G"
1505:
1488:
1143:
1126:
4148:
4112:
3955:
3950:
3945:
3940:
2867:
1937:
678:
3920:
960:
3156:
1583:
1566:
1360:"A common inhibitory receptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells"
4158:
3724:
3218:
2904:
828:
4105:
3363:
2899:
145:
120:
1949:
861:"A novel inhibitory receptor (ILT3) expressed on monocytes, macrophages, and dendritic cells involved in antigen processing"
4055:
3860:
3332:
3327:
3272:
3006:
2455:
1524:"Tetrameric complexes of human histocompatibility leukocyte antigen (HLA)-G bind to peripheral blood myelomonocytic cells"
824:
3554:
3277:
1070:"Human LilrB2 is a Ī²-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model"
70:
2872:
784:
158:
3584:
2009:
800:
151:
1280:"A new human gene complex encoding the killer cell inhibitory receptors and related monocyte/macrophage receptors"
4153:
2450:
1859:
1403:"Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules"
1168:"Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules"
4048:
3634:
2529:
1931:
961:"Entrez Gene: LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2"
3598:
464:
460:
456:
452:
448:
2941:
2936:
2931:
2921:
2228:
2156:
772:
2285:
2203:
134:
1446:"A family of human lymphoid and myeloid Ig-like receptors, some of which bind to MHC class I molecules"
1489:"The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes"
1127:"The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes"
3522:
3235:
1852:
1740:
1291:
1081:
759:
LILBR2 plays a critical role in the inhibition of axonal regeneration and functional recovery after
57:
3549:
3368:
1955:
1943:
1927:
632:
628:
624:
620:
616:
567:
563:
559:
555:
551:
2956:
2690:
1670:
1633:
1596:
1475:
1432:
1317:
1197:
1050:
939:
859:
Cella M, Dƶhring C, Samaridis J, Dessing M, Brockhaus M, Lanzavecchia A, et al. (May 1997).
94:
1567:"Functional characterization of HLA-F and binding of HLA-F tetramers to ILT2 and ILT4 receptors"
1220:
Suciu-Foca N, Cortesini R (July 2007). "Central role of ILT3 in the T suppressor cell cascade".
642:
577:
1401:
Colonna M, Samaridis J, Cella M, Angman L, Allen RL, O'Callaghan CA, et al. (April 1998).
1166:
Colonna M, Samaridis J, Cella M, Angman L, Allen RL, O'Callaghan CA, et al. (April 1998).
1068:
Kim T, Vidal GS, Djurisic M, William CM, Birnbaum ME, Garcia KC, et al. (September 2013).
1832:
1803:
1768:
1727:
Shiroishi M, Tsumoto K, Amano K, Shirakihara Y, Colonna M, Braud VM, et al. (July 2003).
1715:
1662:
1625:
1588:
1553:
1510:
1467:
1424:
1389:
1346:
1309:
1266:
1237:
1189:
1148:
1107:
1042:
1007:
931:
890:
768:
50:
4089:
4032:
1522:
Allan DS, Colonna M, Lanier LL, Churakova TD, Abrams JS, Ellis SA, et al. (April 1999).
1358:
Colonna M, Navarro F, BellĆ³n T, Llano M, GarcĆa P, Samaridis J, et al. (December 1997).
4085:
4077:
3729:
3462:
3383:
2946:
2139:
2065:
1824:
1793:
1758:
1748:
1705:
1695:
1654:
1617:
1578:
1565:
Lepin EJ, Bastin JM, Allan DS, Roncador G, Braud VM, Mason DY, et al. (December 2000).
1543:
1535:
1500:
1457:
1414:
1379:
1371:
1338:
1299:
1258:
1229:
1179:
1138:
1097:
1089:
1034:
997:
987:
976:"Inhibition of PirB Activity by TAT-PEP Improves Mouse Motor Ability and Cognitive Behavior"
921:
880:
872:
238:
169:
90:
61:, ILT4, MIR10, LIR2, MIR-10, LIR-2, leukocyte immunoglobulin like receptor B2, ILT-4, CD85D
3789:
2325:
2320:
2243:
213:
1744:
1295:
1085:
3574:
2996:
2507:
2310:
1548:
1523:
1384:
1359:
1102:
1069:
1002:
975:
885:
860:
4020:
1780:
Nakajima H, Asai A, Okada A, Ping L, Hamajima F, Sata T, et al. (December 2003).
1763:
1728:
1710:
1683:
1487:
Fanger NA, Cosman D, Peterson L, Braddy SC, Maliszewski CR, Borges L (November 1998).
1342:
1304:
1279:
1125:
Fanger NA, Cosman D, Peterson L, Braddy SC, Maliszewski CR, Borges L (November 1998).
4132:
3544:
3001:
2092:
1968:
1436:
1262:
1201:
1054:
1682:
Willcox BE, Thomas LM, Chapman TL, Heikema AP, West AP, Bjorkman PJ (October 2002).
1674:
1600:
1479:
1321:
3900:
3208:
3198:
2729:
2695:
1637:
943:
764:
760:
231:
111:
1233:
1828:
1798:
1781:
1462:
1445:
98:
3910:
3559:
3337:
3312:
3011:
2633:
2559:
2033:
1419:
1402:
1184:
1167:
846:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1733:
Proceedings of the
National Academy of Sciences of the United States of America
4028:
3840:
3564:
3245:
2986:
2862:
2495:
2490:
2485:
2340:
2124:
1506:
10.1002/(SICI)1521-4141(199811)28:11<3423::AID-IMMU3423>3.0.CO;2-2
1144:
10.1002/(SICI)1521-4141(199811)28:11<3423::AID-IMMU3423>3.0.CO;2-2
1038:
128:
78:
992:
3679:
3674:
3669:
3659:
3654:
3649:
3644:
1753:
1375:
1093:
876:
373:
331:
252:
197:
184:
86:
1836:
1807:
1772:
1719:
1666:
1629:
1592:
1557:
1539:
1241:
1111:
1046:
1011:
926:
909:
1700:
1621:
1514:
1471:
1428:
1393:
1350:
1313:
1270:
1193:
1152:
935:
894:
721:
3985:
3885:
3699:
3684:
2887:
2882:
2790:
2480:
710:
515:
1584:
10.1002/1521-4141(200012)30:12<3552::AID-IMMU3552>3.0.CO;2-L
3935:
3930:
3925:
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3123:
3118:
3113:
3108:
3103:
3021:
2714:
2554:
2549:
2544:
2539:
2534:
2005:
739:
501:
438:
1278:
Wagtmann N, Rojo S, Eichler E, Mohrenweiser H, Long EO (August 1997).
3875:
3835:
3820:
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3799:
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3709:
3517:
3487:
3451:
3442:
3255:
3223:
3087:
3082:
3052:
3031:
2991:
2951:
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2795:
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2668:
2663:
2653:
2522:
2517:
2512:
2460:
2445:
2315:
2305:
2268:
2263:
2181:
2176:
691:
395:
17:
1895:: Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G
974:
Mi YJ, Chen H, Guo N, Sun MY, Zhao ZH, Gao XC, et al. (2017).
4000:
3975:
3895:
3890:
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3870:
3855:
3850:
3845:
3830:
3784:
3769:
3734:
3719:
3714:
3704:
3624:
3619:
3614:
3593:
3589:
3579:
3492:
3393:
3388:
3347:
3297:
3292:
3287:
3282:
3267:
3260:
3240:
3228:
3171:
3166:
3161:
3151:
3146:
3139:
3077:
3067:
3062:
3057:
3047:
3026:
3016:
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2976:
2971:
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2961:
2916:
2911:
2877:
2842:
2837:
2832:
2822:
2810:
2805:
2785:
2780:
2775:
2770:
2724:
2616:
2611:
2430:
2414:
2407:
2402:
2397:
2392:
2387:
2382:
2357:
2335:
2330:
2223:
2149:
2144:
2134:
1658:
788:
3995:
3990:
3980:
3970:
3965:
3960:
3915:
3905:
3865:
3794:
3764:
3759:
3754:
3749:
3744:
3739:
3694:
3664:
3569:
3537:
3532:
3512:
3502:
3497:
3482:
3477:
3378:
3373:
3342:
3322:
3317:
3307:
3302:
3181:
3134:
3094:
2749:
2744:
2739:
2734:
2719:
2710:
2705:
2700:
2685:
2643:
2638:
2628:
2623:
2606:
2601:
2596:
2591:
2586:
2581:
2576:
2571:
2566:
2502:
2475:
2470:
2465:
2440:
2435:
2372:
2367:
2362:
2352:
2347:
2300:
2295:
2290:
2280:
2275:
2258:
2253:
2248:
2238:
2233:
2218:
2213:
2208:
2198:
2193:
2188:
2171:
2166:
2161:
2112:
2080:
2075:
2070:
2053:
2048:
2043:
2038:
746:
74:
1978:
1848:
1444:
Borges L, Hsu ML, Fanger N, Kubin M, Cosman D (December 1997).
3507:
2119:
2107:
2102:
2097:
2087:
2060:
2028:
1844:
736:
Leukocyte immunoglobulin-like receptor subfamily B member 2
221:
4093:
4036:
763:. However, recent studies demonstrate that LILRB2 is a
343:
1782:"Transcriptional regulation of ILT family receptors"
3813:
3607:
3356:
3040:
2763:
2423:
2021:
656:
615:
591:
550:
820:
818:
816:
767:receptor and may contribute to synaptic loss and
168:
27:Protein-coding gene in the species Homo sapiens
4113:
4056:
1990:
1860:
8:
4120:
4106:
4063:
4049:
1997:
1983:
1975:
1965:United States National Library of Medicine
1867:
1853:
1845:
612:
547:
443:
369:
209:
106:
2014:list of human clusters of differentiation
1930:at the U.S. National Library of Medicine
1797:
1762:
1752:
1709:
1699:
1582:
1547:
1504:
1461:
1418:
1383:
1303:
1183:
1142:
1101:
1001:
991:
925:
884:
1963:This article incorporates text from the
955:
953:
1882:
812:
754:leukocyte immunoglobulin-like receptor
31:
908:Samaridis J, Colonna M (March 1997).
173:
132:
127:
7:
4074:
4072:
4017:
4015:
1528:The Journal of Experimental Medicine
1364:The Journal of Experimental Medicine
1027:Molecular and Cellular Neurosciences
865:The Journal of Experimental Medicine
4092:. You can help Knowledge (XXG) by
4035:. You can help Knowledge (XXG) by
653:
588:
525:
506:
482:
419:
400:
348:
309:
247:
226:
25:
742:that in humans is encoded by the
4076:
4019:
1900:
1885:
157:
150:
144:
119:
980:Frontiers in Aging Neuroscience
1571:European Journal of Immunology
1493:European Journal of Immunology
1131:European Journal of Immunology
914:European Journal of Immunology
332:More reference expression data
1:
1343:10.1016/S0378-1119(97)00411-3
1305:10.1016/S0960-9822(06)00263-6
1234:10.1016/j.cellimm.2007.01.013
752:This gene is a member of the
142:
4139:Genes on human chromosome 19
1829:10.1016/j.humimm.2004.04.003
1799:10.4049/jimmunol.171.12.6611
1463:10.4049/jimmunol.159.11.5192
1263:10.1016/0378-1119(94)90802-8
4144:Clusters of differentiation
2010:clusters of differentiation
1942:human gene location in the
1420:10.4049/jimmunol.160.7.3096
1185:10.4049/jimmunol.160.7.3096
4175:
4149:Immunoglobulin superfamily
4071:
4014:
1954:human gene details in the
801:Cluster of differentiation
1880:
1039:10.1016/j.mcn.2021.103630
842:"Human PubMed Reference:"
783:LILRB2 has been shown to
725:
720:
716:
709:
690:
673:
660:
639:
608:
595:
574:
543:
532:
528:
513:
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500:
489:
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472:
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407:
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394:
379:
372:
368:
356:
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342:
329:
316:
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259:
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220:
212:
208:
191:
178:
141:
118:
109:
105:
68:
65:
55:
48:
43:
39:
34:
1932:Medical Subject Headings
993:10.3389/fnagi.2017.00199
679:Chr 19: 54.27 ā 54.28 Mb
1754:10.1073/pnas.1431057100
1376:10.1084/jem.186.11.1809
1094:10.1126/science.1242077
877:10.1084/jem.185.10.1743
295:upper lobe of left lung
4159:Membrane protein stubs
4088:ārelated article is a
1688:BMC Structural Biology
1540:10.1084/jem.189.7.1149
927:10.1002/eji.1830270313
1928:LILRB2+protein,+human
1786:Journal of Immunology
1701:10.1186/1472-6807-2-6
1622:10.1007/s002510100332
1450:Journal of Immunology
1407:Journal of Immunology
1172:Journal of Immunology
135:Chromosome 19 (human)
769:cognitive impairment
1956:UCSC Genome Browser
1944:UCSC Genome Browser
1745:2003PNAS..100.8856S
1296:1997CBio....7..615W
1222:Cellular Immunology
1086:2013Sci...341.1399K
1080:(6152): 1399ā1404.
773:Alzheimer's disease
1967:, which is in the
99:LILRB2 - orthologs
4101:
4100:
4044:
4043:
4009:
4008:
1918:
1917:
1792:(12): 6611ā6620.
1739:(15): 8856ā8861.
1647:Nature Immunology
1577:(12): 3552ā3561.
1499:(11): 3423ā3434.
1456:(11): 5192ā5196.
1370:(11): 1809ā1818.
1137:(11): 3423ā3434.
871:(10): 1743ā1751.
733:
732:
729:
728:
705:
704:
669:
668:
650:
649:
604:
603:
585:
584:
539:
538:
522:
521:
496:
495:
479:
478:
433:
432:
416:
415:
364:
363:
360:
359:
338:
337:
325:
324:
306:
305:
287:bone marrow cells
204:
203:
16:(Redirected from
4166:
4154:Immunology stubs
4122:
4115:
4108:
4086:membrane protein
4080:
4073:
4065:
4058:
4051:
4023:
4016:
1999:
1992:
1985:
1976:
1904:
1889:
1869:
1862:
1855:
1846:
1840:
1817:Human Immunology
1811:
1801:
1776:
1766:
1756:
1723:
1713:
1703:
1678:
1641:
1604:
1586:
1561:
1551:
1534:(7): 1149ā1156.
1518:
1508:
1483:
1465:
1440:
1422:
1413:(7): 3096ā3100.
1397:
1387:
1354:
1337:(1ā2): 149ā156.
1325:
1307:
1274:
1257:(1ā2): 171ā174.
1245:
1206:
1205:
1187:
1178:(7): 3096ā3100.
1163:
1157:
1156:
1146:
1122:
1116:
1115:
1105:
1065:
1059:
1058:
1022:
1016:
1015:
1005:
995:
971:
965:
964:
957:
948:
947:
929:
905:
899:
898:
888:
856:
850:
849:
838:
832:
822:
718:
717:
701:
686:
681:
664:
654:
645:
613:
609:RefSeq (protein)
599:
589:
580:
548:
526:
507:
483:
468:
444:
420:
401:
370:
349:
334:
310:
255:
253:Top expressed in
248:
227:
210:
200:
187:
176:
161:
154:
148:
137:
123:
107:
101:
60:
53:
32:
21:
4174:
4173:
4169:
4168:
4167:
4165:
4164:
4163:
4129:
4128:
4127:
4126:
4070:
4069:
4012:
4010:
4005:
3809:
3603:
3352:
3036:
2759:
2419:
2017:
2003:
1924:
1919:
1914:
1911:
1905:
1896:
1890:
1876:
1873:
1843:
1814:
1779:
1726:
1681:
1644:
1607:
1564:
1521:
1486:
1443:
1400:
1357:
1328:
1284:Current Biology
1277:
1248:
1219:
1215:
1213:Further reading
1210:
1209:
1165:
1164:
1160:
1124:
1123:
1119:
1067:
1066:
1062:
1024:
1023:
1019:
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906:
902:
858:
857:
853:
840:
839:
835:
823:
814:
809:
797:
781:
722:View/Edit Human
699:
684:
677:
674:Location (UCSC)
662:
641:
635:
631:
627:
623:
619:
597:
576:
570:
566:
562:
558:
554:
467:
465:ENSG00000277751
463:
461:ENSG00000276146
459:
457:ENSG00000131042
455:
453:ENSG00000275463
451:
449:ENSG00000274513
447:
330:
321:
302:
297:
293:
289:
285:
281:
277:
273:
269:
265:
251:
195:
182:
174:
164:
163:
162:
155:
133:
110:Gene location (
69:
56:
49:
28:
23:
22:
15:
12:
11:
5:
4172:
4170:
4162:
4161:
4156:
4151:
4146:
4141:
4131:
4130:
4125:
4124:
4117:
4110:
4102:
4099:
4098:
4081:
4068:
4067:
4060:
4053:
4045:
4042:
4041:
4024:
4007:
4006:
4004:
4003:
3998:
3993:
3988:
3983:
3978:
3973:
3968:
3963:
3958:
3953:
3948:
3943:
3938:
3933:
3928:
3923:
3918:
3913:
3908:
3903:
3898:
3893:
3888:
3883:
3878:
3873:
3868:
3863:
3858:
3853:
3848:
3843:
3838:
3833:
3828:
3823:
3817:
3815:
3811:
3810:
3808:
3807:
3802:
3797:
3792:
3787:
3782:
3777:
3772:
3767:
3762:
3757:
3752:
3747:
3742:
3737:
3732:
3727:
3722:
3717:
3712:
3707:
3702:
3697:
3692:
3687:
3682:
3677:
3672:
3667:
3662:
3657:
3652:
3647:
3642:
3637:
3632:
3627:
3622:
3617:
3611:
3609:
3605:
3604:
3602:
3601:
3596:
3587:
3582:
3577:
3572:
3567:
3562:
3557:
3552:
3547:
3542:
3541:
3540:
3535:
3525:
3520:
3515:
3510:
3505:
3500:
3495:
3490:
3485:
3480:
3475:
3470:
3465:
3460:
3454:
3445:
3440:
3439:
3438:
3433:
3423:
3418:
3417:
3416:
3411:
3401:
3396:
3391:
3386:
3381:
3376:
3371:
3366:
3360:
3358:
3354:
3353:
3351:
3350:
3345:
3340:
3335:
3330:
3325:
3320:
3315:
3310:
3305:
3300:
3295:
3290:
3285:
3280:
3275:
3270:
3265:
3264:
3263:
3258:
3248:
3243:
3238:
3233:
3232:
3231:
3226:
3221:
3211:
3206:
3201:
3196:
3191:
3190:
3189:
3184:
3174:
3169:
3164:
3159:
3154:
3149:
3144:
3143:
3142:
3137:
3127:
3121:
3116:
3111:
3106:
3097:
3092:
3091:
3090:
3085:
3080:
3070:
3065:
3060:
3055:
3050:
3044:
3042:
3038:
3037:
3035:
3034:
3029:
3024:
3019:
3014:
3009:
3004:
2999:
2994:
2989:
2984:
2979:
2974:
2969:
2964:
2959:
2954:
2949:
2944:
2939:
2934:
2929:
2924:
2919:
2914:
2909:
2908:
2907:
2902:
2892:
2891:
2890:
2885:
2875:
2870:
2865:
2860:
2855:
2850:
2845:
2840:
2835:
2830:
2825:
2820:
2815:
2814:
2813:
2808:
2798:
2793:
2788:
2783:
2778:
2773:
2767:
2765:
2761:
2760:
2758:
2757:
2752:
2747:
2742:
2737:
2732:
2727:
2722:
2717:
2708:
2703:
2698:
2693:
2688:
2683:
2682:
2681:
2676:
2671:
2666:
2661:
2656:
2646:
2641:
2636:
2631:
2626:
2621:
2620:
2619:
2614:
2604:
2599:
2594:
2589:
2584:
2579:
2574:
2569:
2564:
2563:
2562:
2557:
2552:
2547:
2542:
2537:
2527:
2526:
2525:
2520:
2515:
2505:
2500:
2499:
2498:
2493:
2488:
2478:
2473:
2468:
2463:
2458:
2453:
2448:
2443:
2438:
2433:
2427:
2425:
2421:
2420:
2418:
2417:
2412:
2411:
2410:
2405:
2400:
2395:
2390:
2385:
2375:
2370:
2365:
2360:
2355:
2350:
2345:
2344:
2343:
2338:
2333:
2328:
2318:
2313:
2308:
2303:
2298:
2293:
2288:
2283:
2278:
2273:
2272:
2271:
2266:
2256:
2251:
2246:
2241:
2236:
2231:
2226:
2221:
2216:
2211:
2206:
2201:
2196:
2191:
2186:
2185:
2184:
2179:
2169:
2164:
2159:
2154:
2153:
2152:
2147:
2142:
2137:
2127:
2122:
2117:
2116:
2115:
2105:
2100:
2095:
2090:
2085:
2084:
2083:
2078:
2073:
2063:
2058:
2057:
2056:
2051:
2046:
2041:
2036:
2025:
2023:
2019:
2018:
2004:
2002:
2001:
1994:
1987:
1979:
1960:
1959:
1947:
1935:
1923:
1922:External links
1920:
1916:
1915:
1913:
1912:
1906:
1899:
1897:
1891:
1884:
1881:
1878:
1877:
1874:
1872:
1871:
1864:
1857:
1849:
1842:
1841:
1823:(7): 700ā705.
1812:
1777:
1724:
1679:
1653:(3): 237ā243.
1642:
1616:(4): 270ā278.
1610:Immunogenetics
1605:
1562:
1519:
1484:
1441:
1398:
1355:
1326:
1290:(8): 615ā618.
1275:
1246:
1216:
1214:
1211:
1208:
1207:
1158:
1117:
1060:
1017:
966:
949:
920:(3): 660ā665.
900:
851:
833:
811:
810:
808:
805:
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803:
796:
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780:
777:
731:
730:
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280:
276:
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268:
264:
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244:
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235:
224:
218:
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214:RNA expression
206:
205:
202:
201:
193:
189:
188:
180:
177:
172:
166:
165:
156:
149:
143:
139:
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67:
63:
62:
54:
46:
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40:
37:
36:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
4171:
4160:
4157:
4155:
4152:
4150:
4147:
4145:
4142:
4140:
4137:
4136:
4134:
4123:
4118:
4116:
4111:
4109:
4104:
4103:
4097:
4095:
4091:
4087:
4082:
4079:
4075:
4066:
4061:
4059:
4054:
4052:
4047:
4046:
4040:
4038:
4034:
4031:article is a
4030:
4025:
4022:
4018:
4013:
4002:
3999:
3997:
3994:
3992:
3989:
3987:
3984:
3982:
3979:
3977:
3974:
3972:
3969:
3967:
3964:
3962:
3959:
3957:
3954:
3952:
3949:
3947:
3944:
3942:
3939:
3937:
3934:
3932:
3929:
3927:
3924:
3922:
3919:
3917:
3914:
3912:
3909:
3907:
3904:
3902:
3899:
3897:
3894:
3892:
3889:
3887:
3884:
3882:
3879:
3877:
3874:
3872:
3869:
3867:
3864:
3862:
3859:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3834:
3832:
3829:
3827:
3824:
3822:
3819:
3818:
3816:
3812:
3806:
3803:
3801:
3798:
3796:
3793:
3791:
3788:
3786:
3783:
3781:
3778:
3776:
3773:
3771:
3768:
3766:
3763:
3761:
3758:
3756:
3753:
3751:
3748:
3746:
3743:
3741:
3738:
3736:
3733:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3711:
3708:
3706:
3703:
3701:
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3683:
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3648:
3646:
3643:
3641:
3638:
3636:
3633:
3631:
3628:
3626:
3623:
3621:
3618:
3616:
3613:
3612:
3610:
3606:
3600:
3597:
3595:
3591:
3588:
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3583:
3581:
3578:
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3573:
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3568:
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3531:
3530:
3529:
3526:
3524:
3521:
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3516:
3514:
3511:
3509:
3506:
3504:
3501:
3499:
3496:
3494:
3491:
3489:
3486:
3484:
3481:
3479:
3476:
3474:
3471:
3469:
3466:
3464:
3461:
3458:
3455:
3453:
3449:
3446:
3444:
3441:
3437:
3434:
3432:
3429:
3428:
3427:
3424:
3422:
3419:
3415:
3412:
3410:
3407:
3406:
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3402:
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3372:
3370:
3367:
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3359:
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3331:
3329:
3326:
3324:
3321:
3319:
3316:
3314:
3311:
3309:
3306:
3304:
3301:
3299:
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3289:
3286:
3284:
3281:
3279:
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3271:
3269:
3266:
3262:
3259:
3257:
3254:
3253:
3252:
3249:
3247:
3244:
3242:
3239:
3237:
3234:
3230:
3227:
3225:
3222:
3220:
3217:
3216:
3215:
3212:
3210:
3207:
3205:
3202:
3200:
3197:
3195:
3192:
3188:
3185:
3183:
3180:
3179:
3178:
3175:
3173:
3170:
3168:
3165:
3163:
3160:
3158:
3155:
3153:
3150:
3148:
3145:
3141:
3138:
3136:
3133:
3132:
3131:
3128:
3125:
3122:
3120:
3117:
3115:
3112:
3110:
3107:
3105:
3101:
3098:
3096:
3093:
3089:
3086:
3084:
3081:
3079:
3076:
3075:
3074:
3071:
3069:
3066:
3064:
3061:
3059:
3056:
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3049:
3046:
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3039:
3033:
3030:
3028:
3025:
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3020:
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3015:
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3008:
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3000:
2998:
2995:
2993:
2990:
2988:
2985:
2983:
2980:
2978:
2975:
2973:
2970:
2968:
2965:
2963:
2960:
2958:
2955:
2953:
2950:
2948:
2945:
2943:
2940:
2938:
2935:
2933:
2930:
2928:
2925:
2923:
2920:
2918:
2915:
2913:
2910:
2906:
2903:
2901:
2898:
2897:
2896:
2893:
2889:
2886:
2884:
2881:
2880:
2879:
2876:
2874:
2871:
2869:
2866:
2864:
2861:
2859:
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2841:
2839:
2836:
2834:
2831:
2829:
2826:
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2816:
2812:
2809:
2807:
2804:
2803:
2802:
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2792:
2789:
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2784:
2782:
2779:
2777:
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2772:
2769:
2768:
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2736:
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2731:
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2726:
2723:
2721:
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2709:
2707:
2704:
2702:
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2697:
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2692:
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2687:
2684:
2680:
2677:
2675:
2672:
2670:
2667:
2665:
2662:
2660:
2657:
2655:
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2647:
2645:
2642:
2640:
2637:
2635:
2632:
2630:
2627:
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2618:
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2613:
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2609:
2608:
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2603:
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2380:
2379:
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2369:
2366:
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2361:
2359:
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2339:
2337:
2334:
2332:
2329:
2327:
2324:
2323:
2322:
2319:
2317:
2314:
2312:
2309:
2307:
2304:
2302:
2299:
2297:
2294:
2292:
2289:
2287:
2284:
2282:
2279:
2277:
2274:
2270:
2267:
2265:
2262:
2261:
2260:
2257:
2255:
2252:
2250:
2247:
2245:
2242:
2240:
2237:
2235:
2232:
2230:
2227:
2225:
2222:
2220:
2217:
2215:
2212:
2210:
2207:
2205:
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2195:
2192:
2190:
2187:
2183:
2180:
2178:
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2173:
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2168:
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2163:
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2158:
2155:
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2148:
2146:
2143:
2141:
2138:
2136:
2133:
2132:
2131:
2128:
2126:
2123:
2121:
2118:
2114:
2111:
2110:
2109:
2106:
2104:
2101:
2099:
2096:
2094:
2091:
2089:
2086:
2082:
2079:
2077:
2074:
2072:
2069:
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2064:
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2055:
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2047:
2045:
2042:
2040:
2037:
2035:
2032:
2031:
2030:
2027:
2026:
2024:
2020:
2015:
2011:
2007:
2000:
1995:
1993:
1988:
1986:
1981:
1980:
1977:
1973:
1972:
1970:
1969:public domain
1966:
1957:
1953:
1952:
1948:
1945:
1941:
1940:
1936:
1933:
1929:
1926:
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1921:
1909:
1903:
1898:
1894:
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1879:
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1707:
1702:
1697:
1693:
1689:
1685:
1680:
1676:
1672:
1668:
1664:
1660:
1659:10.1038/ni760
1656:
1652:
1648:
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1639:
1635:
1631:
1627:
1623:
1619:
1615:
1611:
1606:
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1327:
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1297:
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1276:
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1268:
1264:
1260:
1256:
1252:
1247:
1243:
1239:
1235:
1231:
1227:
1223:
1218:
1217:
1212:
1203:
1199:
1195:
1191:
1186:
1181:
1177:
1173:
1169:
1162:
1159:
1154:
1150:
1145:
1140:
1136:
1132:
1128:
1121:
1118:
1113:
1109:
1104:
1099:
1095:
1091:
1087:
1083:
1079:
1075:
1071:
1064:
1061:
1056:
1052:
1048:
1044:
1040:
1036:
1032:
1028:
1021:
1018:
1013:
1009:
1004:
999:
994:
989:
985:
981:
977:
970:
967:
962:
956:
954:
950:
945:
941:
937:
933:
928:
923:
919:
915:
911:
904:
901:
896:
892:
887:
882:
878:
874:
870:
866:
862:
855:
852:
847:
843:
837:
834:
830:
826:
821:
819:
817:
813:
806:
802:
799:
798:
794:
792:
790:
786:
778:
776:
774:
770:
766:
762:
757:
755:
750:
748:
745:
741:
737:
723:
719:
715:
712:
708:
698:
696:
693:
689:
683:
680:
676:
672:
665:
659:
655:
652:
646:
644:
638:
634:
630:
626:
622:
618:
614:
611:
607:
600:
594:
590:
587:
581:
579:
573:
569:
565:
561:
557:
553:
549:
546:
544:RefSeq (mRNA)
542:
535:
531:
527:
524:
518:
517:
512:
508:
505:
503:
499:
492:
488:
484:
481:
475:
471:
466:
462:
458:
454:
450:
445:
442:
440:
436:
429:
425:
421:
418:
412:
411:
406:
402:
399:
397:
393:
390:
387:
385:
382:
378:
375:
371:
367:
355:
350:
347:
345:
341:
333:
328:
318:
315:
311:
308:
298:
294:
290:
286:
282:
278:
274:
270:
266:
262:
261:
258:
254:
249:
246:
245:
242:
240:
236:
234:
233:
229:
228:
225:
223:
219:
215:
211:
207:
199:
194:
190:
186:
181:
171:
167:
160:
153:
147:
140:
136:
130:
126:
122:
117:
113:
108:
104:
100:
96:
92:
88:
84:
80:
76:
72:
64:
59:
52:
47:
42:
38:
33:
30:
19:
4094:expanding it
4083:
4037:expanding it
4026:
4011:
3527:
3447:
3425:
3403:
3250:
3213:
3176:
3129:
3099:
3072:
2894:
2800:
2658:
2648:
2377:
2129:
1962:
1961:
1950:
1938:
1907:
1892:
1820:
1816:
1789:
1785:
1736:
1732:
1691:
1687:
1650:
1646:
1613:
1609:
1574:
1570:
1531:
1527:
1496:
1492:
1453:
1449:
1410:
1406:
1367:
1363:
1334:
1330:
1287:
1283:
1254:
1250:
1228:(1): 59ā67.
1225:
1221:
1175:
1171:
1161:
1134:
1130:
1120:
1077:
1073:
1063:
1030:
1026:
1020:
983:
979:
969:
917:
913:
903:
868:
864:
854:
845:
836:
782:
779:Interactions
761:brain injury
758:
751:
743:
735:
734:
661:
640:
633:NP_001265335
629:NP_001265334
625:NP_001265333
621:NP_001265332
617:NP_001074447
596:
575:
568:NM_001278406
564:NM_001278405
560:NM_001278404
556:NM_001278403
552:NM_001080978
533:
514:
490:
473:
427:
408:
388:
383:
237:
230:
66:External IDs
29:
1875:PDB gallery
283:bone marrow
267:granulocyte
196:54,281,184
183:54,273,812
44:Identifiers
4133:Categories
4029:immunology
2012:(see also
1033:: 103630.
831:, May 2017
807:References
291:right lung
241:(ortholog)
79:HomoloGene
1437:255370078
1202:255370078
1055:235203153
765:Ī²-Amyloid
643:NP_005865
578:NM_005874
374:Orthologs
87:GeneCards
2006:Proteins
1837:15301858
1808:14662864
1773:12853576
1720:12390682
1675:35400503
1667:11875462
1630:11491530
1601:42462661
1593:11169396
1558:10190906
1480:36907307
1322:14484039
1242:17923119
1112:24052308
1047:34029694
1012:28676756
827:–
795:See also
785:interact
711:Wikidata
299:testicle
279:appendix
263:monocyte
175:19q13.42
3814:301ā350
3608:251ā300
3560:CD240CE
3357:201ā250
3041:151ā200
2764:101ā150
1741:Bibcode
1638:2819935
1549:2193000
1515:9842885
1472:9548455
1429:9531263
1394:9382880
1385:2199153
1351:9373149
1314:9259559
1292:Bibcode
1271:8125298
1194:9531263
1153:9842885
1103:3853120
1082:Bibcode
1074:Science
1003:5476690
986:: 199.
944:2212182
936:9079806
895:9151699
886:2196312
829:Ensembl
740:protein
502:UniProt
439:Ensembl
380:Species
216:pattern
51:Aliases
3821:CD300A
3780:CDw293
3565:CD240D
3426:CD213a
3404:CDw210
3369:CD202b
3343:CDw199
3338:CDw198
2992:CD140b
2424:51ā100
1951:LILRB2
1939:LILRB2
1934:(MeSH)
1835:
1806:
1771:
1764:166403
1761:
1718:
1711:130215
1708:
1673:
1665:
1636:
1628:
1599:
1591:
1556:
1546:
1513:
1478:
1470:
1435:
1427:
1392:
1382:
1349:
1320:
1312:
1269:
1240:
1200:
1192:
1151:
1110:
1100:
1053:
1045:
1010:
1000:
942:
934:
893:
883:
744:LILRB2
694:search
692:PubMed
516:A2IXV5
396:Entrez
344:BioGPS
275:spleen
91:LILRB2
83:136797
75:604815
58:LILRB2
35:LILRB2
4084:This
4027:This
4001:CD350
3996:CD349
3991:CD344
3986:CD340
3981:CD339
3976:CD338
3971:CD337
3966:CD336
3961:CD335
3956:CD334
3951:CD333
3946:CD332
3941:CD331
3936:CD329
3931:CD328
3926:CD327
3921:CD326
3916:CD325
3911:CD324
3906:CD322
3901:CD321
3896:CD320
3891:CD318
3886:CD317
3881:CD316
3876:CD315
3871:CD314
3866:CD312
3861:CD309
3856:CD307
3851:CD306
3846:CD305
3841:CD304
3836:CD303
3831:CD302
3826:CD301
3805:CD299
3800:CD298
3795:CD297
3790:CD295
3785:CD294
3775:CD292
3770:CD290
3765:CD289
3760:CD288
3755:CD286
3750:CD284
3745:CD283
3740:CD282
3735:CD281
3730:CD280
3725:CD279
3720:CD278
3715:CD276
3710:CD275
3705:CD274
3700:CD273
3695:CD272
3690:CD271
3685:CD269
3680:CD268
3675:CD267
3670:CD266
3665:CD265
3660:CD264
3655:CD263
3650:CD262
3645:CD261
3640:CD258
3635:CD257
3630:CD256
3625:CD254
3620:CD253
3615:CD252
3599:CD249
3594:CD248
3590:CD247
3585:CD246
3580:CD244
3575:CD243
3570:CD241
3555:CD239
3550:CD238
3545:CD236
3528:CD235
3523:CD234
3518:CD233
3513:CD230
3508:CD229
3503:CD228
3498:CD227
3493:CD226
3488:CD225
3483:CD224
3478:CD223
3473:CD222
3468:CD221
3463:CD220
3448:CD218
3443:CD217
3421:CD212
3399:CD209
3394:CD208
3389:CD207
3384:CD206
3379:CD205
3374:CD204
3364:CD201
3348:CD200
3333:CD197
3328:CD196
3323:CD195
3318:CD194
3313:CD193
3308:CD192
3303:CD191
3298:CD186
3293:CD185
3288:CD184
3283:CD183
3278:CD182
3273:CD181
3268:CD180
3251:CD179
3246:CD178
3241:CD177
3236:CD174
3214:CD172
3209:CD171
3204:CD170
3199:CD169
3194:CD168
3177:CD167
3172:CD166
3167:CD164
3162:CD163
3157:CD162
3152:CD161
3147:CD160
3130:CD159
3100:CD158
3095:CD157
3073:CD156
3068:CD155
3063:CD154
3058:CD153
3053:CD152
3048:CD151
3032:CD150
3027:CD148
3022:CD147
3017:CD146
3012:CD144
3007:CD143
3002:CD142
2997:CD141
2987:CD138
2982:CD137
2977:CD136
2972:CD135
2967:CD134
2962:CD133
2957:CD132
2952:CD131
2947:CD130
2942:CD129
2937:CD127
2932:CD126
2927:CD125
2922:CD124
2917:CD123
2912:CD122
2895:CD121
2878:CD120
2873:CD119
2868:CD118
2863:CD117
2858:CD116
2853:CD115
2848:CD114
2843:CD113
2838:CD112
2833:CD111
2828:CD110
2823:CD109
2818:CD108
2801:CD107
2796:CD106
2791:CD105
2786:CD104
2781:CD103
2776:CD102
2771:CD101
2755:CD100
1694:: 6.
1671:S2CID
1634:S2CID
1597:S2CID
1476:S2CID
1433:S2CID
1318:S2CID
1198:S2CID
1051:S2CID
940:S2CID
789:PTPN6
787:with
738:is a
410:10288
389:Mouse
384:Human
271:blood
239:Mouse
232:Human
179:Start
112:Human
18:CD85d
4090:stub
4033:stub
2750:CD99
2745:CD98
2740:CD97
2735:CD96
2730:CD95
2725:CD94
2720:CD93
2715:CD92
2711:CD91
2706:CD90
2701:CD89
2696:CD88
2691:CD87
2686:CD86
2649:CD85
2644:CD84
2639:CD83
2634:CD82
2629:CD81
2624:CD80
2607:CD79
2602:CD78
2597:CD74
2592:CD73
2587:CD72
2582:CD71
2577:CD70
2572:CD69
2567:CD68
2530:CD66
2508:CD64
2503:CD63
2481:CD62
2476:CD61
2471:CD59
2466:CD58
2461:CD57
2456:CD56
2451:CD55
2446:CD54
2441:CD53
2436:CD52
2431:CD51
2415:CD50
2378:CD49
2373:CD48
2368:CD47
2363:CD46
2358:CD45
2353:CD44
2348:CD43
2321:CD42
2316:CD41
2311:CD40
2306:CD39
2301:CD38
2296:CD37
2291:CD36
2286:CD35
2281:CD34
2276:CD33
2259:CD32
2254:CD31
2249:CD30
2244:CD29
2239:CD28
2234:CD27
2229:CD26
2224:CD25
2219:CD24
2214:CD23
2209:CD22
2204:CD21
2199:CD20
2194:CD19
2189:CD18
2172:CD16
2167:CD15
2162:CD14
2157:CD13
2130:CD11
2125:CD10
2022:1ā50
1908:2gw5
1893:2dyp
1833:PMID
1804:PMID
1769:PMID
1716:PMID
1663:PMID
1626:PMID
1589:PMID
1554:PMID
1511:PMID
1468:PMID
1425:PMID
1390:PMID
1347:PMID
1331:Gene
1310:PMID
1267:PMID
1251:Gene
1238:PMID
1190:PMID
1149:PMID
1108:PMID
1043:PMID
1008:PMID
932:PMID
891:PMID
747:gene
222:Bgee
170:Band
129:Chr.
71:OMIM
2120:CD9
2108:CD8
2103:CD7
2098:CD6
2093:CD5
2088:CD4
2066:CD3
2061:CD2
2034:a-c
2029:CD1
1825:doi
1794:doi
1790:171
1759:PMC
1749:doi
1737:100
1706:PMC
1696:doi
1655:doi
1618:doi
1579:doi
1544:PMC
1536:doi
1532:189
1501:doi
1458:doi
1454:159
1415:doi
1411:160
1380:PMC
1372:doi
1368:186
1339:doi
1335:200
1300:doi
1259:doi
1255:138
1230:doi
1226:248
1180:doi
1176:160
1139:doi
1098:PMC
1090:doi
1078:341
1035:doi
1031:114
998:PMC
988:doi
922:doi
881:PMC
873:doi
869:185
771:in
700:n/a
685:n/a
663:n/a
598:n/a
534:n/a
491:n/a
474:n/a
428:n/a
352:n/a
319:n/a
192:End
95:OMA
4135::
3592:-
2713:-
2054:1E
2049:1D
2044:1B
2039:1A
2008::
1831:.
1821:65
1819:.
1802:.
1788:.
1784:.
1767:.
1757:.
1747:.
1735:.
1731:.
1714:.
1704:.
1690:.
1686:.
1669:.
1661:.
1649:.
1632:.
1624:.
1614:53
1612:.
1595:.
1587:.
1575:30
1573:.
1569:.
1552:.
1542:.
1530:.
1526:.
1509:.
1497:28
1495:.
1491:.
1474:.
1466:.
1452:.
1448:.
1431:.
1423:.
1409:.
1405:.
1388:.
1378:.
1366:.
1362:.
1345:.
1333:.
1316:.
1308:.
1298:.
1286:.
1282:.
1265:.
1253:.
1236:.
1224:.
1196:.
1188:.
1174:.
1170:.
1147:.
1135:28
1133:.
1129:.
1106:.
1096:.
1088:.
1076:.
1072:.
1049:.
1041:.
1029:.
1006:.
996:.
982:.
978:.
952:^
938:.
930:.
918:27
916:.
912:.
889:.
879:.
867:.
863:.
844:.
815:^
791:.
775:.
749:.
198:bp
185:bp
93:;
89::
85:;
81::
77:;
73::
4121:e
4114:t
4107:v
4096:.
4064:e
4057:t
4050:v
4039:.
3538:b
3533:a
3459:)
3457:b
3452:a
3450:(
3436:2
3431:1
3414:b
3409:a
3261:b
3256:a
3229:g
3224:b
3219:a
3187:b
3182:a
3140:c
3135:a
3126:)
3124:k
3119:i
3114:e
3109:d
3104:a
3102:(
3088:c
3083:b
3078:a
2905:b
2900:a
2888:b
2883:a
2811:b
2806:a
2679:k
2674:j
2669:h
2664:e
2659:d
2654:a
2617:b
2612:a
2560:f
2555:e
2550:d
2545:c
2540:b
2535:a
2523:C
2518:B
2513:A
2496:P
2491:L
2486:E
2408:f
2403:e
2398:d
2393:c
2388:b
2383:a
2341:d
2336:c
2331:b
2326:a
2269:B
2264:A
2182:B
2177:A
2150:d
2145:c
2140:b
2135:a
2113:a
2081:Īµ
2076:Ī“
2071:Ī³
2016:)
1998:e
1991:t
1984:v
1971:.
1958:.
1946:.
1868:e
1861:t
1854:v
1839:.
1827::
1810:.
1796::
1775:.
1751::
1743::
1722:.
1698::
1692:2
1677:.
1657::
1651:3
1640:.
1620::
1603:.
1581::
1560:.
1538::
1517:.
1503::
1482:.
1460::
1439:.
1417::
1396:.
1374::
1353:.
1341::
1324:.
1302::
1294::
1288:7
1273:.
1261::
1244:.
1232::
1204:.
1182::
1155:.
1141::
1114:.
1092::
1084::
1057:.
1037::
1014:.
990::
984:9
963:.
946:.
924::
897:.
875::
848:.
114:)
97::
20:)
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