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CENPF

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Testa JR, Zhou JY, Bell DW, Yen TJ (Mar 1995). "Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24→q25 and 1q32→q41, respectively, by fluorescence in situ hybridization".
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Waters, Aoife M.; Asfahani, Rowan; Carroll, Paula; Bicknell, Louise; Lescai, Francesco; Bright, Alison; Chanudet, Estelle; Brooks, Anthony; Christou-Savina, Sonja; Osman, Guled; Walsh, Patrick (March 2015).
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Filges, Isabel; Bruder, Elisabeth; Brandal, Kristin; Meier, Stephanie; Undlien, Dag Erik; Waage, Trine Rygvold; Hoesli, Irene; Schubach, Max; de Beer, Tjaart; Sheng, Ying; Hoeller, Sylvia (April 2016).
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Filges, Isabel; Bruder, Elisabeth; Brandal, Kristin; Meier, Stephanie; Undlien, Dag Erik; Waage, Trine Rygvold; Hoesli, Irene; Schubach, Max; de Beer, Tjaart; Sheng, Ying; Hoeller, Sylvia (April 2016).
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at right-angles to each other. Before division, CENPF localises at the end of one of the centrioles (the mother centriole) in order to orient microtubules correctly to
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Konstantinidou AE, Korkolopoulou P, Kavantzas N, et al. (2003). "Mitosin, a novel marker of cell proliferation and early recurrence in intracranial meningiomas".
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Erlanson M, Casiano CA, Tan EM, et al. (1999). "Immunohistochemical analysis of the proliferation associated nuclear antigen CENP-F in non-Hodgkin's lymphoma".
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Rattner JB, Rao A, Fritzler MJ, Valencia DW, Yen TJ (Mar 1994). "CENP-F is a .ca 400 kDa kinetochore protein that exhibits a cell-cycle dependent localization".
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Li Q, Ke Y, Kapp JA, et al. (1995). "A novel cell-cycle-dependent 350-kDa nuclear protein: C-terminal domain sufficient for nuclear localization".
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Laoukili J, Kooistra MR, Brás A, et al. (2005). "FoxM1 is required for execution of the mitotic programme and chromosome stability".
1194:) in order for the microtubules to pull them apart in the process of dividing the cell. It remains part of the kinetochore through early 2110:"Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules" 1053: 241: 1719: 1060: 2371: 1968:"Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1" 218: 1495: 1370: 1349: 1890:"Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression" 1783:"CENP-F is a protein of the nuclear matrix that assembles onto kinetochores at late G2 and is rapidly degraded after mitosis" 1366: 1725: 140: 115: 2493: 1855:"The C terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization" 1345: 1218:
lead to impaired cell division during early development. Mitosis has been found to take longer when the gene is mutated.
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disrupt this ability to form cilia; cilia have been found to be fewer in number and shorter when the gene is mutated.
254: 153: 247: 146: 2640: 1293: 2694: 2478: 2251:"Mitosin/CENP-F is a conserved kinetochore protein subjected to cytoplasmic dynein-mediated poleward transport" 1250: 902: 65: 2143:
Kobayashi M, Hanai R (2001). "M phase-specific association of human topoisomerase IIIbeta with chromosomes".
1933:"Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs" 2075:"The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene family" 1421: 883: 2207:
Holstein SA, Hohl RJ (2003). "Synergistic interaction of lovastatin and paclitaxel in human cancer cells".
2647: 2630: 2600: 2573: 1127: 2635: 2533: 2855: 2780: 2765: 2595: 2543: 2518: 2458: 1207: 129: 44: 2523: 1731: 1281: 991: 2309: 1697: 1615: 89: 1017: 970: 2585: 2497: 2344: 2301: 2272: 2237: 2216: 2195: 2160: 2131: 2096: 2061: 2040: 1997: 1954: 1919: 1876: 1841: 1812: 1769: 1689: 1681: 1607: 1599: 1554: 1536: 1474: 1438: 1199: 1191: 1183: 37: 2775: 2674: 2334: 2293: 2262: 2185: 2152: 2121: 2086: 2030: 2022: 1987: 1979: 1944: 1909: 1901: 1866: 1833: 1802: 1794: 1759: 1671: 1589: 1544: 1528: 1517:"The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes" 1466: 1430: 334: 265: 209: 164: 2830: 2825: 85: 2667: 2488: 2436: 1285: 1246: 1175: 309: 2174:"Farnesylation of Cenp-F is required for G2/M progression and degradation after mitosis" 2558: 2482: 1992: 1967: 1807: 1782: 1549: 1516: 1289: 1226: 1155: 2035: 2010: 1914: 1889: 772: 767: 762: 757: 752: 747: 742: 737: 732: 727: 722: 717: 712: 707: 702: 697: 692: 687: 682: 666: 661: 656: 651: 646: 641: 636: 631: 626: 621: 616: 611: 606: 601: 596: 591: 586: 581: 576: 571: 566: 550: 545: 540: 535: 530: 525: 2892: 2538: 1131: 512: 2313: 2011:"Structural requirements and dynamics of mitosin-kinetochore interaction in M phase" 69: 2513: 2387: 1701: 1619: 1238: 1222: 1187: 1139: 1135: 327: 106: 1532: 93: 2732: 2727: 2590: 2568: 2563: 2431: 1406:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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and are necessary for cells to have diverse, complex shapes and
1123: 61: 2360: 1496:"Entrez Gene: CENPF centromere protein F, 350/400ka (mitosin)" 48:, CENF, PRO1779, hcp-1, CILD31, STROMS, centromere protein F 1292:
against CENPF have been found in patients with cancer or
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Microtubules are protein structures that are part of the
1198:(the chromosome-dividing phase). In late anaphase, CENPF 1166:(the phase of rapid protein synthesis in preparation for 317: 2878:
International System for Human Cytogenetic Nomenclature
2073:
Goodwin RL, Pabón-Peña LM, Foster GC, Bader D (1999).
1245:. Most cilia are primary cilia, which are involved in 482: 2848: 2751: 2713: 2683: 2611: 2467: 2398: 1031: 1010: 984: 963: 763:
negative regulation of transcription, DNA-templated
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regulation of G2/M transition of mitotic cell cycle
1634:"OMIM Entry - # 243605 - STROMME SYNDROME; STROMS" 1362: 1360: 1358: 1341: 1339: 1337: 1888:Zhu X, Mancini MA, Chang KH, et al. (1995). 1781:Liao H, Winkfein RJ, Mack G, et al. (1995). 264: 163: 688:regulation of striated muscle tissue development 2108:Ashar HR, James L, Gray K, et al. (2000). 1367:GRCm38: Ensembl release 89: ENSMUSG00000026605 1206:(the cell-dividing phase) it localises to the 16:Centromere- and microtubule-associated protein 2372: 1170:). In late G2, the protein forms part of the 728:mitotic spindle assembly checkpoint signaling 8: 1931:Li S, Ku CY, Farmer AA, et al. (1998). 2321:Zhou X, Wang R, Fan L, et al. (2005). 1853:Zhu X, Chang KH, He D, et al. (1995). 1346:GRCh38: Ensembl release 89: ENSG00000117724 1134:. It also has a role in the orientation of 2710: 2379: 2365: 2357: 2249:Yang ZY, Guo J, Li N, et al. (2004). 798: 508: 305: 204: 101: 2338: 2266: 2189: 2125: 2090: 2034: 1991: 1948: 1913: 1870: 1806: 1763: 1675: 1593: 1548: 449:fetal liver hematopoietic progenitor cell 1490: 1488: 1333: 1233:, which contains a pair of cylindrical 18: 2868:List of organisms by chromosome count 1570: 1568: 269: 230: 225: 168: 127: 122: 7: 1509: 1507: 1505: 1966:Chan GK, Schaar BT, Yen TJ (1998). 1210:. It is thought to be subsequently 1260:CENPF is thought to form either a 1249:to trigger migration, division or 1028: 1007: 981: 960: 938: 919: 893: 874: 848: 829: 743:multicellular organism development 487: 405: 343: 322: 14: 1241:thin cellular projections called 1119:that in humans is encoded by the 526:protein homodimerization activity 253: 246: 240: 217: 152: 145: 139: 114: 2489:Macrochromosome/Microchromosome 1202:to the spindle midzone, and in 632:perinuclear region of cytoplasm 1229:ability. They are made by the 723:ventricular system development 652:chromosome, centromeric region 471:More reference expression data 1: 2172:Hussein D, Taylor SS (2003). 2145:Biochem. Biophys. Res. Commun 1826:Biochem. Biophys. Res. Commun 1533:10.1136/jmedgenet-2014-102691 758:cell population proliferation 238: 137: 1746:Ma L, Zhao X, Zhu X (2006). 1276:Mutations in both copies of 531:transcription factor binding 2899:Genes on human chromosome 1 1521:Journal of Medical Genetics 698:metaphase plate congression 379:stromal cell of endometrium 2915: 2529:Dinoflagellate chromosomes 1730:gene details page in the 541:protein C-terminus binding 453:superior cervical ganglion 391:mucosa of transverse colon 2873:List of sequenced genomes 2641:Chromosomal translocation 2514:A chromosome/B chromosome 2505:(or accessory chromosome) 1765:10.1007/s11373-005-9057-3 1402:"Mouse PubMed Reference:" 1384:"Human PubMed Reference:" 1294:graft-versus-host disease 1099: 1094: 1090: 1083: 1067: 1061:Chr 1: 189.37 – 189.42 Mb 1048: 1035: 1014: 1003: 988: 967: 956: 945: 941: 926: 922: 913: 900: 896: 881: 877: 868: 855: 851: 836: 832: 823: 808: 801: 797: 781: 511: 507: 495: 490: 481: 468: 417: 408: 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 2695:Telomere-binding protein 2509:Supernumerary chromosome 2092:10.1074/jbc.274.26.18597 1872:10.1074/jbc.270.33.19545 1054:Chr 1: 214.6 – 214.66 Mb 733:regulation of cell cycle 718:muscle organ development 703:DNA biosynthetic process 612:ciliary transition fiber 2191:10.1242/jcs.115.17.3403 1950:10.1074/jbc.273.11.6183 1422:Cell Motil Cytoskeleton 2631:Structural alterations 2340:10.1074/jbc.M414310200 2157:10.1006/bbrc.2001.5580 2127:10.1074/jbc.M003469200 1838:10.1006/bbrc.1995.1959 1471:10.1006/geno.1994.1558 1128:chromosome segregation 713:chromosome segregation 551:dynein complex binding 2648:Numerical alterations 2636:Chromosomal inversion 2534:Homologous chromosome 2268:10.1038/sj.cr.7290172 2027:10.1128/MCB.19.2.1016 1906:10.1128/MCB.15.9.5017 1799:10.1083/jcb.130.3.507 1272:Clinical significance 1154:CENPF is part of the 457:mandibular prominence 2856:Extrachromosomal DNA 2544:Satellite chromosome 2519:Lampbrush chromosome 2459:Nuclear organization 1984:10.1083/jcb.143.1.49 1724:genome location and 1435:10.1002/cm.970260305 1208:intercellular bridge 1126:. It is involved in 1113:Centromere protein F 768:kinetochore assembly 693:cell differentiation 437:maxillary prominence 271:1 H6|1 95.03 cM 232:Chromosome 1 (mouse) 130:Chromosome 1 (human) 2549:Centromere position 2524:Polytene chromosome 2494:Circular chromosome 2230:Histol. Histopathol 1732:UCSC Genome Browser 363:ganglionic eminence 2184:(Pt 17): 3403–14. 1677:10.1002/humu.22960 1595:10.1002/humu.22960 903:ENSMUSG00000026605 773:mitotic cell cycle 708:kidney development 676:Biological process 572:ciliary basal body 560:Cellular component 519:Molecular function 2886: 2885: 2844: 2843: 2581:Centromere number 2498:Linear chromosome 2085:(26): 18597–604. 1192:spindle apparatus 1184:sister chromatids 1110: 1109: 1106: 1105: 1079: 1078: 1044: 1043: 1025: 1024: 999: 998: 978: 977: 952: 951: 935: 934: 909: 908: 890: 889: 864: 863: 845: 844: 793: 792: 748:protein transport 627:outer kinetochore 536:chromatin binding 503: 502: 499: 498: 477: 476: 464: 463: 402: 401: 387:bone marrow cells 300: 299: 199: 198: 94:CENPF - orthologs 2906: 2711: 2675:Polyploidization 2503:Extra chromosome 2418:Genetic material 2381: 2374: 2367: 2358: 2352: 2342: 2317: 2280: 2270: 2245: 2224: 2209:Mol. Cancer Ther 2203: 2193: 2168: 2139: 2129: 2104: 2094: 2069: 2048: 2038: 2005: 1995: 1962: 1952: 1927: 1917: 1884: 1874: 1865:(33): 19545–50. 1849: 1820: 1810: 1777: 1767: 1706: 1705: 1679: 1654: 1648: 1647: 1645: 1644: 1630: 1624: 1623: 1597: 1572: 1563: 1562: 1552: 1511: 1500: 1499: 1492: 1483: 1482: 1453: 1447: 1446: 1416: 1410: 1409: 1398: 1392: 1391: 1380: 1374: 1364: 1353: 1343: 1282:Strømme syndrome 1178:that allows the 1174:, a disc-shaped 1092: 1091: 1063: 1056: 1039: 1029: 1020: 1008: 1004:RefSeq (protein) 994: 982: 973: 961: 939: 920: 894: 875: 849: 830: 799: 592:nuclear envelope 509: 488: 473: 445:secondary oocyte 441:ventricular zone 433:genital tubercle 413: 411:Top expressed in 406: 359:ventricular zone 351: 349:Top expressed in 344: 323: 306: 296: 283: 272: 257: 250: 244: 233: 221: 205: 195: 182: 171: 156: 149: 143: 132: 118: 102: 96: 47: 40: 19: 2914: 2913: 2909: 2908: 2907: 2905: 2904: 2903: 2889: 2888: 2887: 2882: 2840: 2747: 2709: 2679: 2668:Paleopolyploidy 2613: 2607: 2463: 2437:Heterochromatin 2400: 2394: 2385: 2355: 2333:(14): 13973–7. 2320: 2298:10.1038/ncb1217 2283: 2248: 2227: 2206: 2171: 2142: 2120:(39): 30451–7. 2107: 2072: 2051: 2015:Mol. Cell. Biol 2008: 1965: 1930: 1894:Mol. Cell. Biol 1887: 1852: 1823: 1780: 1745: 1741: 1739:Further reading 1715: 1710: 1709: 1656: 1655: 1651: 1642: 1640: 1632: 1631: 1627: 1574: 1573: 1566: 1513: 1512: 1503: 1494: 1493: 1486: 1455: 1454: 1450: 1418: 1417: 1413: 1400: 1399: 1395: 1382: 1381: 1377: 1365: 1356: 1344: 1335: 1330: 1302: 1286:jejunal atresia 1274: 1253:. Mutations in 1251:differentiation 1247:cell signalling 1214:. Mutations in 1176:protein complex 1152: 1101:View/Edit Mouse 1096:View/Edit Human 1059: 1052: 1049:Location (UCSC) 1037: 1016: 990: 969: 884:ENSG00000117724 777: 671: 555: 546:protein binding 469: 460: 455: 451: 447: 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 381: 377: 375:trabecular bone 373: 369: 365: 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 2912: 2910: 2902: 2901: 2891: 2890: 2884: 2883: 2881: 2880: 2875: 2870: 2865: 2864: 2863: 2852: 2850: 2846: 2845: 2842: 2841: 2839: 2838: 2833: 2828: 2823: 2818: 2813: 2808: 2803: 2798: 2793: 2788: 2783: 2778: 2773: 2768: 2763: 2757: 2755: 2749: 2748: 2746: 2745: 2740: 2735: 2730: 2725: 2719: 2717: 2708: 2707: 2702: 2687: 2685: 2681: 2680: 2678: 2677: 2672: 2671: 2670: 2665: 2660: 2655: 2645: 2644: 2643: 2638: 2628: 2623: 2617: 2615: 2609: 2608: 2606: 2605: 2604: 2603: 2598: 2593: 2588: 2578: 2577: 2576: 2571: 2566: 2561: 2559:Submetacentric 2556: 2546: 2541: 2536: 2531: 2526: 2521: 2516: 2511: 2506: 2500: 2491: 2486: 2485:or heterosome) 2479:Sex chromosome 2471: 2469: 2465: 2464: 2462: 2461: 2456: 2451: 2446: 2441: 2440: 2439: 2434: 2424: 2415: 2410: 2404: 2402: 2396: 2395: 2386: 2384: 2383: 2376: 2369: 2361: 2354: 2353: 2318: 2286:Nat. Cell Biol 2281: 2246: 2225: 2204: 2169: 2140: 2105: 2070: 2049: 2021:(2): 1016–24. 2009:Zhu X (1999). 2006: 1963: 1943:(11): 6183–9. 1928: 1900:(9): 5017–29. 1885: 1850: 1821: 1778: 1752:J. Biomed. Sci 1742: 1740: 1737: 1736: 1735: 1714: 1713:External links 1711: 1708: 1707: 1670:(4): 359–363. 1664:Human Mutation 1649: 1625: 1588:(4): 359–363. 1582:Human Mutation 1564: 1527:(3): 147–156. 1501: 1484: 1448: 1411: 1393: 1375: 1354: 1332: 1331: 1329: 1326: 1325: 1324: 1317: 1310: 1301: 1298: 1290:Autoantibodies 1273: 1270: 1156:nuclear matrix 1151: 1148: 1108: 1107: 1104: 1103: 1098: 1088: 1087: 1081: 1080: 1077: 1076: 1074: 1072: 1065: 1064: 1057: 1050: 1046: 1045: 1042: 1041: 1033: 1032: 1026: 1023: 1022: 1012: 1011: 1005: 1001: 1000: 997: 996: 986: 985: 979: 976: 975: 965: 964: 958: 954: 953: 950: 949: 943: 942: 936: 933: 932: 924: 923: 917: 911: 910: 907: 906: 898: 897: 891: 888: 887: 879: 878: 872: 866: 865: 862: 861: 853: 852: 846: 843: 842: 834: 833: 827: 821: 820: 815: 810: 806: 805: 795: 794: 791: 790: 779: 778: 776: 775: 770: 765: 760: 755: 750: 745: 740: 735: 730: 725: 720: 715: 710: 705: 700: 695: 690: 685: 679: 677: 673: 672: 670: 669: 664: 659: 654: 649: 644: 639: 634: 629: 624: 619: 614: 609: 604: 599: 597:nuclear matrix 594: 589: 584: 579: 574: 569: 563: 561: 557: 556: 554: 553: 548: 543: 538: 533: 528: 522: 520: 516: 515: 505: 504: 501: 500: 497: 496: 493: 492: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 429:tail of embryo 426: 425:primary oocyte 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 388: 384: 380: 376: 372: 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 2911: 2900: 2897: 2896: 2894: 2879: 2876: 2874: 2871: 2869: 2866: 2862: 2859: 2858: 2857: 2854: 2853: 2851: 2847: 2837: 2834: 2832: 2829: 2827: 2824: 2822: 2819: 2817: 2814: 2812: 2809: 2807: 2804: 2802: 2799: 2797: 2794: 2792: 2789: 2787: 2784: 2782: 2779: 2777: 2774: 2772: 2769: 2767: 2764: 2762: 2759: 2758: 2756: 2754: 2750: 2744: 2741: 2739: 2736: 2734: 2731: 2729: 2726: 2724: 2721: 2720: 2718: 2716: 2712: 2706: 2703: 2700: 2696: 2692: 2689: 2688: 2686: 2682: 2676: 2673: 2669: 2666: 2664: 2661: 2659: 2656: 2654: 2651: 2650: 2649: 2646: 2642: 2639: 2637: 2634: 2633: 2632: 2629: 2627: 2624: 2622: 2619: 2618: 2616: 2614:and evolution 2610: 2602: 2599: 2597: 2594: 2592: 2589: 2587: 2584: 2583: 2582: 2579: 2575: 2572: 2570: 2567: 2565: 2562: 2560: 2557: 2555: 2552: 2551: 2550: 2547: 2545: 2542: 2540: 2539:Isochromosome 2537: 2535: 2532: 2530: 2527: 2525: 2522: 2520: 2517: 2515: 2512: 2510: 2507: 2504: 2501: 2499: 2495: 2492: 2490: 2487: 2484: 2480: 2476: 2473: 2472: 2470: 2466: 2460: 2457: 2455: 2452: 2450: 2447: 2445: 2442: 2438: 2435: 2433: 2430: 2429: 2428: 2425: 2423: 2419: 2416: 2414: 2411: 2409: 2406: 2405: 2403: 2397: 2393: 2389: 2382: 2377: 2375: 2370: 2368: 2363: 2362: 2359: 2350: 2346: 2341: 2336: 2332: 2328: 2327:J. Biol. Chem 2324: 2319: 2315: 2311: 2307: 2303: 2299: 2295: 2292:(2): 126–36. 2291: 2287: 2282: 2278: 2274: 2269: 2264: 2261:(4): 275–83. 2260: 2256: 2252: 2247: 2243: 2239: 2235: 2231: 2226: 2222: 2218: 2214: 2210: 2205: 2201: 2197: 2192: 2187: 2183: 2179: 2175: 2170: 2166: 2162: 2158: 2154: 2150: 2146: 2141: 2137: 2133: 2128: 2123: 2119: 2115: 2114:J. Biol. Chem 2111: 2106: 2102: 2098: 2093: 2088: 2084: 2080: 2079:J. Biol. Chem 2076: 2071: 2067: 2063: 2059: 2055: 2050: 2046: 2042: 2037: 2032: 2028: 2024: 2020: 2016: 2012: 2007: 2003: 1999: 1994: 1989: 1985: 1981: 1977: 1973: 1969: 1964: 1960: 1956: 1951: 1946: 1942: 1938: 1937:J. Biol. Chem 1934: 1929: 1925: 1921: 1916: 1911: 1907: 1903: 1899: 1895: 1891: 1886: 1882: 1878: 1873: 1868: 1864: 1860: 1859:J. Biol. Chem 1856: 1851: 1847: 1843: 1839: 1835: 1831: 1827: 1822: 1818: 1814: 1809: 1804: 1800: 1796: 1793:(3): 507–18. 1792: 1788: 1784: 1779: 1775: 1771: 1766: 1761: 1758:(2): 205–13. 1757: 1753: 1749: 1744: 1743: 1738: 1733: 1729: 1728: 1723: 1722: 1717: 1716: 1712: 1703: 1699: 1695: 1691: 1687: 1683: 1678: 1673: 1669: 1665: 1661: 1653: 1650: 1639: 1635: 1629: 1626: 1621: 1617: 1613: 1609: 1605: 1601: 1596: 1591: 1587: 1583: 1579: 1571: 1569: 1565: 1560: 1556: 1551: 1546: 1542: 1538: 1534: 1530: 1526: 1522: 1518: 1510: 1508: 1506: 1502: 1497: 1491: 1489: 1485: 1480: 1476: 1472: 1468: 1464: 1460: 1452: 1449: 1444: 1440: 1436: 1432: 1429:(3): 214–26. 1428: 1424: 1423: 1415: 1412: 1407: 1403: 1397: 1394: 1389: 1385: 1379: 1376: 1372: 1368: 1363: 1361: 1359: 1355: 1351: 1347: 1342: 1340: 1338: 1334: 1327: 1323: 1322: 1318: 1316: 1315: 1311: 1309: 1308: 1304: 1303: 1299: 1297: 1295: 1291: 1287: 1283: 1279: 1271: 1269: 1267: 1263: 1258: 1256: 1252: 1248: 1244: 1240: 1236: 1232: 1228: 1224: 1219: 1217: 1213: 1209: 1205: 1201: 1197: 1193: 1190:(forming the 1189: 1186:to attach to 1185: 1181: 1177: 1173: 1169: 1165: 1161: 1157: 1149: 1147: 1145: 1141: 1137: 1133: 1132:cell division 1129: 1125: 1122: 1118: 1114: 1102: 1097: 1093: 1089: 1086: 1082: 1075: 1073: 1070: 1066: 1062: 1058: 1055: 1051: 1047: 1040: 1034: 1030: 1027: 1021: 1019: 1013: 1009: 1006: 1002: 995: 993: 987: 983: 980: 974: 972: 966: 962: 959: 957:RefSeq (mRNA) 955: 948: 944: 940: 937: 931: 930: 925: 921: 918: 916: 912: 905: 904: 899: 895: 892: 886: 885: 880: 876: 873: 871: 867: 860: 859: 854: 850: 847: 841: 840: 835: 831: 828: 826: 822: 819: 816: 814: 811: 807: 804: 800: 796: 789: 785: 780: 774: 771: 769: 766: 764: 761: 759: 756: 754: 751: 749: 746: 744: 741: 739: 738:cell division 736: 734: 731: 729: 726: 724: 721: 719: 716: 714: 711: 709: 706: 704: 701: 699: 696: 694: 691: 689: 686: 684: 681: 680: 678: 675: 674: 668: 665: 663: 660: 658: 655: 653: 650: 648: 645: 643: 640: 638: 635: 633: 630: 628: 625: 623: 620: 618: 615: 613: 610: 608: 605: 603: 600: 598: 595: 593: 590: 588: 585: 583: 580: 578: 575: 573: 570: 568: 565: 564: 562: 559: 558: 552: 549: 547: 544: 542: 539: 537: 534: 532: 529: 527: 524: 523: 521: 518: 517: 514: 513:Gene ontology 510: 506: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 2785: 2580: 2548: 2388:Cytogenetics 2330: 2326: 2289: 2285: 2258: 2254: 2236:(1): 67–74. 2233: 2229: 2215:(2): 141–9. 2212: 2208: 2181: 2177: 2151:(1): 282–7. 2148: 2144: 2117: 2113: 2082: 2078: 2060:(1): 69–74. 2057: 2053: 2018: 2014: 1978:(1): 49–63. 1975: 1972:J. Cell Biol 1971: 1940: 1936: 1897: 1893: 1862: 1858: 1832:(1): 220–8. 1829: 1825: 1790: 1787:J. Cell Biol 1786: 1755: 1751: 1726: 1720: 1667: 1663: 1652: 1641:. Retrieved 1638:www.omim.org 1637: 1628: 1585: 1581: 1524: 1520: 1465:(3): 691–3. 1462: 1458: 1451: 1426: 1420: 1414: 1405: 1396: 1387: 1378: 1319: 1312: 1305: 1277: 1275: 1259: 1254: 1223:cytoskeleton 1220: 1215: 1188:microtubules 1153: 1136:microtubules 1120: 1112: 1111: 1036: 1015: 992:NM_001081363 989: 968: 946: 927: 901: 882: 856: 837: 817: 812: 657:cytoskeleton 587:spindle pole 333: 326: 292:189,420,283 279:189,372,803 191:214,664,571 178:214,603,195 53:External IDs 2601:Polycentric 2591:Monocentric 2574:Holocentric 2569:Acrocentric 2564:Telocentric 2554:Metacentric 2432:Euchromatin 2392:chromosomes 2178:J. Cell Sci 2054:Mod. Pathol 1266:heterodimer 1172:kinetochore 1158:during the 667:kinetochore 607:nucleoplasm 395:left testis 383:bone marrow 31:Identifiers 2753:Centromere 2684:Structures 2663:Polyploidy 2653:Aneuploidy 2454:Nucleosome 2444:Chromosome 1643:2018-09-27 1373:, May 2017 1352:, May 2017 1328:References 1235:centrioles 1231:centrosome 1180:centromere 1164:cell cycle 753:cell cycle 637:pronucleus 617:chromosome 582:centrosome 337:(ortholog) 74:HomoloGene 2705:Protamine 2612:Processes 2596:Dicentric 2449:Chromatid 2427:Chromatin 2408:Karyotype 1686:1098-1004 1604:1098-1004 1541:1468-6244 1262:homodimer 1227:migratory 1204:telophase 1200:localises 1142:cellular 1018:NP_057427 971:NM_016343 803:Orthologs 647:chromatin 567:cytoplasm 82:GeneCards 2893:Category 2849:See also 2691:Telomere 2658:Euploidy 2586:Acentric 2483:allosome 2475:Autosome 2401:concepts 2349:15677469 2314:11732068 2306:15654331 2277:12974617 2255:Cell Res 2242:12507285 2221:12467231 2200:12154071 2165:11549288 2136:10852915 2101:10373470 1774:16456711 1694:26820108 1612:26820108 1559:25564561 1459:Genomics 1369:– 1348:– 1300:See also 1212:degraded 1196:anaphase 1160:G2 phase 1150:Function 1085:Wikidata 782:Sources: 371:testicle 2861:Plasmid 2715:Histone 2626:Meiosis 2621:Mitosis 2066:9950165 2045:9891037 2002:9763420 1993:2132809 1959:9497340 1924:7651420 1881:7642639 1846:7612011 1817:7542657 1808:2120529 1702:1495539 1620:1495539 1550:4345935 1479:7851898 1443:7904902 1371:Ensembl 1350:Ensembl 1182:of two 1168:mitosis 1162:of the 1130:during 1117:protein 915:UniProt 870:Ensembl 809:Species 788:QuickGO 662:nucleus 642:axoneme 622:midbody 602:spindle 577:cytosol 312:pattern 70:1313302 38:Aliases 2422:Genome 2413:Ploidy 2347:  2312:  2304:  2275:  2240:  2219:  2198:  2163:  2134:  2099:  2064:  2043:  2036:116032 2033:  2000:  1990:  1957:  1922:  1915:230749 1912:  1879:  1844:  1815:  1805:  1772:  1718:Human 1700:  1692:  1684:  1618:  1610:  1602:  1557:  1547:  1539:  1477:  1441:  1280:cause 1071:search 1069:PubMed 929:P49454 858:108000 825:Entrez 483:BioGPS 421:zygote 62:600236 2699:TINF2 2468:Types 2399:Basic 2310:S2CID 1727:CENPF 1721:CENPF 1698:S2CID 1616:S2CID 1321:CENPT 1314:CENPJ 1307:CENPE 1278:CENPF 1255:CENPF 1243:cilia 1216:CENPF 1144:cilia 1121:CENPF 1115:is a 818:Mouse 813:Human 784:Amigo 367:gonad 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 86:CENPF 78:22969 45:CENPF 22:CENPF 2481:(or 2345:PMID 2302:PMID 2273:PMID 2238:PMID 2217:PMID 2196:PMID 2161:PMID 2132:PMID 2097:PMID 2062:PMID 2041:PMID 1998:PMID 1955:PMID 1920:PMID 1877:PMID 1842:PMID 1813:PMID 1770:PMID 1690:PMID 1682:ISSN 1608:PMID 1600:ISSN 1555:PMID 1537:ISSN 1475:PMID 1439:PMID 1239:form 1140:form 1124:gene 839:1063 318:Bgee 266:Band 227:Chr. 170:1q41 165:Band 124:Chr. 58:OMIM 2733:H2B 2728:H2A 2335:doi 2331:280 2294:doi 2263:doi 2186:doi 2182:115 2153:doi 2149:287 2122:doi 2118:275 2087:doi 2083:274 2031:PMC 2023:doi 1988:PMC 1980:doi 1976:143 1945:doi 1941:273 1910:PMC 1902:doi 1867:doi 1863:270 1834:doi 1830:212 1803:PMC 1795:doi 1791:130 1760:doi 1672:doi 1590:doi 1545:PMC 1529:doi 1467:doi 1431:doi 1264:or 1138:to 1038:n/a 947:n/a 491:n/a 288:End 187:End 90:OMA 66:MGI 2895:: 2776:C2 2771:C1 2743:H4 2738:H3 2723:H1 2693:: 2390:: 2343:. 2329:. 2325:. 2308:. 2300:. 2288:. 2271:. 2259:13 2257:. 2253:. 2234:18 2232:. 2211:. 2194:. 2180:. 2176:. 2159:. 2147:. 2130:. 2116:. 2112:. 2095:. 2081:. 2077:. 2058:12 2056:. 2039:. 2029:. 2019:19 2017:. 2013:. 1996:. 1986:. 1974:. 1970:. 1953:. 1939:. 1935:. 1918:. 1908:. 1898:15 1896:. 1892:. 1875:. 1861:. 1857:. 1840:. 1828:. 1811:. 1801:. 1789:. 1785:. 1768:. 1756:13 1754:. 1750:. 1696:. 1688:. 1680:. 1668:37 1666:. 1662:. 1636:. 1614:. 1606:. 1598:. 1586:37 1584:. 1580:. 1567:^ 1553:. 1543:. 1535:. 1525:52 1523:. 1519:. 1504:^ 1487:^ 1473:. 1463:23 1461:. 1437:. 1427:26 1425:. 1404:. 1386:. 1357:^ 1336:^ 1296:. 1288:. 1268:. 1146:. 786:/ 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 2836:T 2831:Q 2826:P 2821:O 2816:N 2811:M 2806:K 2801:J 2796:I 2791:H 2786:F 2781:E 2766:B 2761:A 2701:) 2697:( 2496:/ 2477:/ 2420:/ 2380:e 2373:t 2366:v 2351:. 2337:: 2316:. 2296:: 2290:7 2279:. 2265:: 2244:. 2223:. 2213:1 2202:. 2188:: 2167:. 2155:: 2138:. 2124:: 2103:. 2089:: 2068:. 2047:. 2025:: 2004:. 1982:: 1961:. 1947:: 1926:. 1904:: 1883:. 1869:: 1848:. 1836:: 1819:. 1797:: 1776:. 1762:: 1734:. 1704:. 1674:: 1646:. 1622:. 1592:: 1561:. 1531:: 1498:. 1481:. 1469:: 1445:. 1433:: 1408:. 1390:. 212:) 109:) 92::

Index

Aliases
CENPF
OMIM
600236
MGI
1313302
HomoloGene
22969
GeneCards
CENPF
OMA
CENPF - orthologs
Human
Chromosome 1 (human)
Chr.
Chromosome 1 (human)
Chromosome 1 (human)
Genomic location for CENPF
Genomic location for CENPF
Band
bp
bp
Mouse
Chromosome 1 (mouse)
Chr.
Chromosome 1 (mouse)
Genomic location for CENPF
Genomic location for CENPF
Band
bp

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