255:
25:
83:
429:
Snoeck R, Andrei G, Bodaghi B, Lagneaux L, Daelemans D, de Clercq E, et al. (September 2002). "2-Chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide (CMV423), a new lead compound for the treatment of human cytomegalovirus infections".
342:
503:
328:
362:
132:
108:
214:
234:
530:
525:
370:
InChI=1S/C14H14ClN3O/c15-12-11(14(16)19)10-5-1-2-7-18(10)13(12)9-4-3-6-17-8-9/h3-4,6,8H,1-2,5,7H2,(H2,16,19)
535:
486:
Aoki FY (2015). "45 - Antivirals against Herpes
Viruses". In Bennett JE, Blaser MJ, Dolin R (eds.).
250:
401:
149:
35:
499:
447:
491:
439:
409:
271:
203:
158:
223:
397:
254:
495:
405:
443:
519:
468:
183:
488:
Mandell, Douglas, and
Bennett's Principles and Practice of Infectious Diseases
304:
194:
54:
393:
44:
451:
24:
169:
74:
140:
2-Chloro-3-(pyridin-3-yl)-5,6,7,8-tetrahydroindolizine-1-carboxamide
390:
2-chloro-3-pyridin-3-yl-5,6,7,8-tetrahydroindolizine-1-carboxamide
327:
318:
82:
18:
239:
412:
was discontinued by 2018 before entering clinical trials.
49:
39:
316:
303:
270:
265:
233:
213:
193:
168:
148:
123:
107:
102:
94:
89:
404:(HHV-6) infection. The drug was investigated by
396:drug that has been studied for the treatment of
182:
157:
463:
461:
8:
73:
253:
202:
222:
421:
367:
347:
249:
137:
72:
7:
350:c1cc(cnc1)c2c(c(c3n2CCCC3)C(=O)N)Cl
173:
496:10.1016/B978-1-4557-4801-3.00045-X
490:(8th ed.). pp. 546–562.
14:
475:. Springer Nature Switzerland AG.
291:
288:
282:
81:
23:
375:Key:KNGXENHWYNLKBU-UHFFFAOYSA-N
297:
276:
1:
444:10.1016/s0166-3542(02)00074-8
552:
266:Chemical and physical data
358:
338:
128:
80:
38:, as no other articles
392:) is an experimental
400:(CMV) infection and
402:human herpesvirus 6
98:CMV-423; RPR-111423
77:
432:Antiviral Research
57:for suggestions.
47:to this page from
505:978-1-4557-4801-3
383:
382:
329:Interactive image
235:CompTox Dashboard
71:
70:
16:Chemical compound
543:
510:
509:
483:
477:
476:
465:
456:
455:
426:
331:
311:
299:
293:
290:
284:
278:
258:
257:
243:
241:
226:
206:
186:
176:
175:
161:
85:
78:
76:
66:
63:
52:
50:related articles
27:
19:
551:
550:
546:
545:
544:
542:
541:
540:
531:Abandoned drugs
526:Antiviral drugs
516:
515:
514:
513:
506:
485:
484:
480:
467:
466:
459:
428:
427:
423:
418:
398:cytomegalovirus
379:
376:
371:
366:
365:
354:
351:
346:
345:
334:
309:
296:
287:
281:
261:
237:
229:
209:
189:
172:
164:
144:
141:
136:
135:
119:
116:Investigational
67:
61:
58:
48:
45:introduce links
28:
17:
12:
11:
5:
549:
547:
539:
538:
533:
528:
518:
517:
512:
511:
504:
478:
457:
438:(3): 413–424.
420:
419:
417:
414:
406:Sanofi-Aventis
381:
380:
378:
377:
374:
372:
369:
361:
360:
359:
356:
355:
353:
352:
349:
341:
340:
339:
336:
335:
333:
332:
324:
322:
314:
313:
307:
301:
300:
294:
285:
279:
274:
268:
267:
263:
262:
260:
259:
251:DTXSID40333187
246:
244:
231:
230:
228:
227:
219:
217:
211:
210:
208:
207:
199:
197:
191:
190:
188:
187:
179:
177:
166:
165:
163:
162:
154:
152:
146:
145:
143:
142:
139:
131:
130:
129:
126:
125:
121:
120:
118:
117:
113:
111:
105:
104:
100:
99:
96:
92:
91:
87:
86:
69:
68:
55:Find link tool
31:
29:
22:
15:
13:
10:
9:
6:
4:
3:
2:
548:
537:
534:
532:
529:
527:
524:
523:
521:
507:
501:
497:
493:
489:
482:
479:
474:
470:
464:
462:
458:
453:
449:
445:
441:
437:
433:
425:
422:
415:
413:
411:
407:
403:
399:
395:
391:
387:
373:
368:
364:
357:
348:
344:
337:
330:
326:
325:
323:
320:
315:
308:
306:
302:
275:
273:
269:
264:
256:
252:
248:
247:
245:
236:
232:
225:
221:
220:
218:
216:
212:
205:
201:
200:
198:
196:
192:
185:
181:
180:
178:
171:
167:
160:
156:
155:
153:
151:
147:
138:
134:
127:
122:
115:
114:
112:
110:
106:
101:
97:
93:
90:Clinical data
88:
84:
79:
65:
56:
51:
46:
42:
41:
37:
32:This article
30:
26:
21:
20:
536:Chloroarenes
487:
481:
472:
435:
431:
424:
389:
385:
384:
109:Legal status
103:Legal status
59:
33:
473:AdisInsight
410:development
312: g·mol
159:186829-19-6
124:Identifiers
95:Other names
520:Categories
416:References
408:, but its
317:3D model (
305:Molar mass
224:PDX37M872C
195:ChemSpider
150:CAS Number
133:IUPAC name
53:; try the
40:link to it
469:"CMV 423"
394:antiviral
62:July 2016
43:. Please
452:12206879
272:Formula
170:PubChem
502:
450:
386:CMV423
343:SMILES
310:275.74
204:428515
184:489128
75:CMV423
36:orphan
34:is an
363:InChI
319:JSmol
500:ISBN
448:PMID
215:UNII
492:doi
440:doi
240:EPA
174:CID
522::
498:.
471:.
460:^
446:.
436:55
434:.
289:Cl
286:14
280:14
508:.
494::
454:.
442::
388:(
321:)
298:O
295:3
292:N
283:H
277:C
242:)
238:(
64:)
60:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.