330:
307:
204:
229:
1857:
1827:
1887:
1842:
595:
581:
588:
1812:
1797:
29:
1872:
336:
235:
3187:
55:
1485:
Su T, Bao Z, Zhang QY, et al. (2000). "Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone".
1277:
Nelson DR, Zeldin DC, Hoffman SM, Maltais LJ, Wain HM, Nebert DW (May 2004). "Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants".
1572:
Wang H, Tan W, Hao B, et al. (2004). "Substantial reduction in risk of lung adenocarcinoma associated with genetic polymorphism in CYP2A13, the most active cytochrome P450 for the metabolic activation of tobacco-specific carcinogen NNK".
1652:
He XY, Shen J, Ding X, et al. (2005). "Identification of critical amino acid residues of human CYP2A13 for the metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific carcinogen".
1137:. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to
1507:
Zhang X, Su T, Zhang QY, et al. (2002). "Genetic polymorphisms of the human CYP2A13 gene: identification of single-nucleotide polymorphisms and functional characterization of an Arg257Cys variant".
1856:
657:
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
1826:
1886:
1419:
Hoffman SM, Fernandez-Salguero P, Gonzalez FJ, Mohrenweiser HW (1996). "Organization and evolution of the cytochrome P450 CYP2A-2B-2F subfamily gene cluster on human chromosome 19".
2565:
1841:
1594:
Cauffiez C, Lo-Guidice JM, Quaranta S, et al. (2004). "Genetic polymorphism of the human cytochrome CYP2A13 in a French population: implication in lung cancer susceptibility".
343:
242:
3030:
1361:
Fernandez-Salguero P, Gonzalez FJ (1995). "The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis".
1811:
2614:
1796:
2786:
843:
165:
824:
2768:
2764:
1927:
2453:
1236:
Fernandez-Salguero P, Hoffman SM, Cholerton S, Mohrenweiser H, Raunio H, Rautio A, Pelkonen O, Huang JD, Evans WE, Idle JR, et al. (Oct 1995).
3256:
3232:
3037:
2746:
2270:
1871:
3251:
1776:
1218:
1200:
3133:
2690:
2606:
1539:"Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population"
2931:
2630:
1334:
329:
1041:
1238:"A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles"
1048:
2670:
306:
3009:
1316:
2807:
2648:
2527:
2226:
1390:
Smith G, Stubbins MJ, Harries LW, Wolf CR (1999). "Molecular genetics of the human cytochrome P450 monooxygenase superfamily".
1187:
1166:
1141:. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
2993:
2800:
1340:
228:
203:
1183:
1456:
Koskela S, Hakkola J, Hukkanen J, et al. (1999). "Expression of CYP2A genes in human liver and extrahepatic tissues".
52:
2704:
2674:
2634:
2622:
1920:
1162:
2858:
2772:
2760:
145:
1690:
Fujieda M, Yamazaki H, Kiyotani K, et al. (2005). "Eighteen novel polymorphisms of the CYP2A13 gene in
Japanese".
342:
241:
2910:
2610:
2278:
1905:
335:
234:
3225:
2793:
2732:
2728:
2716:
2712:
2708:
3096:
2981:
2750:
1865:: Crystal Structure Of Human Microsomal P450 2A6 with the inhibitor (5-(Pyridin-3-yl)furan-2-yl)methanamine bound
1769:
3261:
3165:
2903:
2850:
2845:
2700:
2551:
1948:
1913:
888:
153:
1623:
Cheng XY, Chen GL, Zhang WX, et al. (2004). "Arg257Cys polymorphism of CYP2A13 in a
Chinese population".
2952:
2825:
869:
2779:
2724:
2720:
2686:
2618:
2200:
3218:
3016:
2522:
217:
2974:
2871:
2742:
2641:
2282:
1762:
667:
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
132:
3126:
2832:
2660:
1346:
2474:
1835:: Microsomal P450 2A6 with the inhibitor N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound
2626:
1678:
1444:
177:
1005:
979:
958:
594:
580:
1895:: Structure of Human Lung Cytochrome P450 2A13 with indole bound in two alternate conformations
1850:: Microsomal P450 2A6 with the inhibitor N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound
1742:
1707:
1670:
1640:
1611:
1582:
1560:
1525:
1495:
1473:
1436:
1407:
1378:
1295:
1259:
1125:
are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of
587:
125:
45:
2104:
173:
1973:
1732:
1699:
1662:
1632:
1603:
1550:
1517:
1465:
1428:
1399:
1370:
1287:
1249:
422:
353:
297:
252:
3075:
1944:
397:
28:
3202:
2383:
1254:
1237:
1469:
758:
753:
748:
743:
727:
722:
717:
712:
707:
702:
686:
681:
676:
671:
666:
661:
656:
651:
646:
641:
636:
3245:
3198:
3158:
3062:
3023:
2945:
2938:
2924:
2884:
2865:
2839:
1374:
1291:
623:
1682:
1448:
2681:
2655:
2559:
2545:
2538:
2444:
2424:
2417:
2400:
2342:
2325:
2318:
2311:
2304:
2297:
2265:
2258:
415:
194:
157:
181:
2251:
2207:
1223:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1205:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1126:
1636:
1607:
498:
1936:
1555:
1538:
314:
211:
161:
1317:"Entrez Gene: CYP2A13 cytochrome P450, family 2, subfamily A, polypeptide 13"
3151:
2352:
1940:
1403:
788:
558:
436:
381:
368:
280:
267:
169:
1746:
1737:
1720:
1711:
1674:
1666:
1644:
1615:
1586:
1564:
1529:
1521:
1499:
1477:
1299:
1440:
1411:
1382:
1263:
1088:
1083:
3108:
3068:
3055:
3000:
2967:
2917:
2895:
2890:
2876:
1072:
933:
914:
2577:
2504:
2494:
2484:
2467:
2457:
2449:
2437:
2433:
2429:
2410:
2362:
2335:
2290:
2286:
2274:
2165:
2160:
2155:
2130:
2125:
2109:
2029:
2024:
1820:: Crystal Structure of Human Microsomal P450 2A6 with Methoxsalen Bound
1703:
1432:
1138:
1130:
1122:
1104:
900:
855:
136:, CPAD, CYP2A, CYPIIA13, cytochrome P450 family 2 subfamily A member 13
102:
98:
94:
90:
86:
82:
78:
74:
2244:
2240:
2230:
2216:
2212:
2180:
2175:
2170:
2150:
2145:
2140:
2135:
2099:
2094:
2089:
2069:
2064:
2059:
2054:
2049:
2044:
2039:
2034:
2019:
2014:
2009:
1999:
1994:
1978:
1968:
1963:
1118:
1056:
810:
3186:
1805:: Crystal Structure of Human Microsomal P450 2A6 with Coumarin Bound
2531:
2393:
2080:
1134:
1117:
This gene encodes a member of the cytochrome P450 superfamily of
773:
769:
3194:
2585:
1111:
149:
1909:
1758:
603:
1754:
1880:: Microsomal P450 2A6 with the inhibitor Adrithiol bound
405:
3206:
1719:
Smith BD, Sanders JL, Porubsky PR, et al. (2007).
570:
3143:
3118:
3047:
2817:
2595:
2514:
2372:
2189:
2118:
2078:
1987:
1956:
1019:
998:
972:
951:
1721:"Structure of the human lung cytochrome P450 2A13"
1179:
1177:
1175:
1158:
1156:
1154:
352:
251:
1537:Saito S, Iida A, Sekine A, et al. (2003).
16:Protein-coding gene in the species Homo sapiens
1184:GRCm38: Ensembl release 89: ENSMUSG00000005547
3226:
1921:
1770:
8:
1163:GRCh38: Ensembl release 89: ENSG00000197838
3233:
3219:
1928:
1914:
1906:
1777:
1763:
1755:
784:
619:
393:
292:
189:
63:
1736:
1554:
1253:
1311:
1309:
723:intracellular membrane-bounded organelle
1792:
1150:
18:
652:arachidonic acid epoxygenase activity
357:
318:
313:
256:
215:
210:
7:
3183:
3181:
1016:
995:
969:
948:
924:
905:
879:
860:
834:
815:
575:
493:
431:
410:
14:
1107:that in humans is encoded by the
3185:
1885:
1870:
1855:
1840:
1825:
1810:
1795:
1375:10.1097/00008571-199512001-00013
1292:10.1097/00008571-200401000-00001
593:
586:
579:
341:
334:
328:
305:
240:
233:
227:
202:
27:
677:coumarin 7-hydroxylase activity
3257:Human chromosome 19 gene stubs
759:organic acid metabolic process
708:endoplasmic reticulum membrane
604:More reference expression data
559:More reference expression data
451:olfactory zone of nasal mucosa
1:
1596:Biochem. Biophys. Res. Commun
1470:10.1016/S0006-2952(99)00015-5
326:
225:
3252:Genes on human chromosome 19
3205:. You can help Knowledge by
744:xenobiotic metabolic process
682:steroid hydroxylase activity
463:paraflocculus of cerebellum
3278:
3180:
1637:10.1016/j.cccn.2004.01.017
1608:10.1016/j.bbrc.2004.03.092
1345:gene details page in the
754:coumarin metabolic process
1790:
1692:Drug Metab. Pharmacokinet
1556:10.1007/s10038-003-0021-7
1369:(Special Issue): S123–8.
1219:"Mouse PubMed Reference:"
1201:"Human PubMed Reference:"
1087:
1082:
1078:
1071:
1055:
1036:
1023:
1002:
991:
976:
955:
944:
931:
927:
912:
908:
899:
886:
882:
867:
863:
854:
841:
837:
822:
818:
809:
794:
787:
783:
767:
622:
618:
601:
578:
569:
556:
505:
496:
483:bronchial epithelial cell
467:mucosa of paranasal sinus
459:quadriceps femoris muscle
443:
434:
404:
396:
392:
375:
362:
325:
304:
295:
291:
274:
261:
224:
201:
192:
188:
143:
140:
130:
123:
118:
71:
66:
49:
44:
39:
35:
26:
21:
749:epoxygenase P450 pathway
1510:J. Pharmacol. Exp. Ther
1404:10.1080/004982598238868
1049:Chr 7: 26.53 – 26.54 Mb
1042:Chr 19: 41.09 – 41.1 Mb
642:oxidoreductase activity
1738:10.1074/jbc.M702361200
1667:10.1124/dmd.104.001370
1522:10.1124/jpet.302.2.416
1121:. The cytochrome P450
687:monooxygenase activity
533:respiratory epithelium
479:epithelium of bronchus
713:endoplasmic reticulum
218:Chromosome 19 (human)
1339:genome location and
1101:Cytochrome P450 2A13
545:olfactory epithelium
521:hepatobiliary system
471:middle frontal gyrus
359:7 A3|7 15.54 cM
320:Chromosome 7 (mouse)
67:List of PDB id codes
40:Available structures
1347:UCSC Genome Browser
182:CYP2A13 - orthologs
3193:This article on a
1704:10.2133/dmpk.18.86
1655:Drug Metab. Dispos
1458:Biochem. Pharmacol
1433:10.1007/bf00173169
889:ENSMUSG00000005547
737:Biological process
703:organelle membrane
696:Cellular component
647:aromatase activity
630:Molecular function
3214:
3213:
3175:
3174:
1903:
1902:
1098:
1097:
1094:
1093:
1067:
1066:
1032:
1031:
1013:
1012:
987:
986:
966:
965:
940:
939:
921:
920:
895:
894:
876:
875:
850:
849:
831:
830:
779:
778:
672:metal ion binding
614:
613:
610:
609:
565:
564:
552:
551:
490:
489:
388:
387:
287:
286:
114:
113:
110:
109:
50:Ortholog search:
3269:
3235:
3228:
3221:
3189:
3182:
1947:(Most belong to
1930:
1923:
1916:
1907:
1889:
1874:
1859:
1844:
1829:
1814:
1799:
1779:
1772:
1765:
1756:
1750:
1740:
1731:(23): 17306–13.
1715:
1686:
1648:
1625:Clin. Chim. Acta
1619:
1590:
1568:
1558:
1533:
1503:
1481:
1452:
1415:
1386:
1363:Pharmacogenetics
1321:
1320:
1313:
1304:
1303:
1280:Pharmacogenetics
1274:
1268:
1267:
1257:
1233:
1227:
1226:
1215:
1209:
1208:
1197:
1191:
1181:
1170:
1160:
1080:
1079:
1051:
1044:
1027:
1017:
1008:
996:
992:RefSeq (protein)
982:
970:
961:
949:
925:
906:
880:
861:
835:
816:
785:
637:iron ion binding
620:
606:
597:
590:
583:
576:
561:
541:nasal epithelium
501:
499:Top expressed in
494:
455:Brodmann area 10
447:nasal epithelium
439:
437:Top expressed in
432:
411:
394:
384:
371:
360:
345:
338:
332:
321:
309:
293:
283:
270:
259:
244:
237:
231:
220:
206:
190:
184:
135:
128:
105:
64:
58:
37:
36:
31:
19:
3277:
3276:
3272:
3271:
3270:
3268:
3267:
3266:
3262:Cytochrome P450
3242:
3241:
3240:
3239:
3178:
3176:
3171:
3139:
3114:
3076:Halloween genes
3043:
2813:
2591:
2510:
2368:
2185:
2114:
2074:
1983:
1952:
1945:cytochrome P450
1934:
1904:
1899:
1896:
1890:
1881:
1875:
1866:
1860:
1851:
1845:
1836:
1830:
1821:
1815:
1806:
1800:
1786:
1783:
1753:
1718:
1689:
1661:(12): 1516–21.
1651:
1622:
1593:
1581:(22): 8057–61.
1571:
1536:
1506:
1484:
1464:(12): 1407–13.
1455:
1418:
1398:(12): 1129–65.
1389:
1360:
1356:
1354:Further reading
1330:
1325:
1324:
1315:
1314:
1307:
1276:
1275:
1271:
1235:
1234:
1230:
1217:
1216:
1212:
1199:
1198:
1194:
1182:
1173:
1161:
1152:
1147:
1089:View/Edit Mouse
1084:View/Edit Human
1047:
1040:
1037:Location (UCSC)
1025:
1004:
978:
957:
870:ENSG00000197838
763:
732:
691:
602:
592:
591:
585:
584:
557:
548:
543:
539:
535:
531:
527:
523:
519:
515:
511:
509:proximal tubule
497:
486:
481:
477:
473:
469:
465:
461:
457:
453:
449:
435:
379:
366:
358:
348:
347:
346:
339:
319:
296:Gene location (
278:
265:
257:
247:
246:
245:
238:
216:
193:Gene location (
144:
131:
124:
73:
51:
17:
12:
11:
5:
3275:
3273:
3265:
3264:
3259:
3254:
3244:
3243:
3238:
3237:
3230:
3223:
3215:
3212:
3211:
3190:
3173:
3172:
3170:
3169:
3162:
3155:
3147:
3145:
3141:
3140:
3138:
3137:
3130:
3122:
3120:
3116:
3115:
3113:
3112:
3105:
3073:
3072:
3071:
3059:
3051:
3049:
3045:
3044:
3042:
3041:
3034:
3027:
3020:
3013:
3006:
3005:
3004:
2997:
2985:
2978:
2971:
2964:
2963:
2962:
2959:
2949:
2942:
2935:
2928:
2921:
2914:
2907:
2900:
2899:
2898:
2893:
2881:
2880:
2879:
2874:
2862:
2855:
2854:
2853:
2848:
2836:
2829:
2821:
2819:
2815:
2814:
2812:
2811:
2804:
2797:
2790:
2783:
2776:
2754:
2736:
2694:
2678:
2664:
2652:
2645:
2638:
2599:
2597:
2593:
2592:
2590:
2589:
2582:
2581:
2580:
2570:
2569:
2568:
2556:
2555:
2554:
2542:
2535:
2518:
2516:
2512:
2511:
2509:
2508:
2498:
2488:
2478:
2471:
2461:
2441:
2421:
2414:
2404:
2397:
2387:
2376:
2374:
2370:
2369:
2367:
2366:
2356:
2346:
2339:
2329:
2322:
2315:
2308:
2301:
2294:
2262:
2255:
2248:
2234:
2220:
2204:
2193:
2191:
2187:
2186:
2184:
2183:
2178:
2173:
2168:
2163:
2158:
2153:
2148:
2143:
2138:
2133:
2128:
2122:
2120:
2116:
2115:
2113:
2112:
2107:
2102:
2097:
2092:
2086:
2084:
2076:
2075:
2073:
2072:
2067:
2062:
2057:
2052:
2047:
2042:
2037:
2032:
2027:
2022:
2017:
2012:
2007:
2002:
1997:
1991:
1989:
1985:
1984:
1982:
1981:
1976:
1971:
1966:
1960:
1958:
1954:
1953:
1935:
1933:
1932:
1925:
1918:
1910:
1901:
1900:
1898:
1897:
1891:
1884:
1882:
1876:
1869:
1867:
1861:
1854:
1852:
1846:
1839:
1837:
1831:
1824:
1822:
1816:
1809:
1807:
1801:
1794:
1791:
1788:
1787:
1784:
1782:
1781:
1774:
1767:
1759:
1752:
1751:
1716:
1687:
1649:
1631:(1–2): 213–6.
1620:
1591:
1569:
1534:
1504:
1494:(18): 5074–9.
1482:
1453:
1427:(6): 894–900.
1416:
1387:
1357:
1355:
1352:
1351:
1350:
1329:
1328:External links
1326:
1323:
1322:
1305:
1269:
1242:Am J Hum Genet
1228:
1210:
1192:
1171:
1149:
1148:
1146:
1143:
1096:
1095:
1092:
1091:
1086:
1076:
1075:
1069:
1068:
1065:
1064:
1062:
1060:
1053:
1052:
1045:
1038:
1034:
1033:
1030:
1029:
1021:
1020:
1014:
1011:
1010:
1000:
999:
993:
989:
988:
985:
984:
974:
973:
967:
964:
963:
953:
952:
946:
942:
941:
938:
937:
929:
928:
922:
919:
918:
910:
909:
903:
897:
896:
893:
892:
884:
883:
877:
874:
873:
865:
864:
858:
852:
851:
848:
847:
839:
838:
832:
829:
828:
820:
819:
813:
807:
806:
801:
796:
792:
791:
781:
780:
777:
776:
765:
764:
762:
761:
756:
751:
746:
740:
738:
734:
733:
731:
730:
725:
720:
715:
710:
705:
699:
697:
693:
692:
690:
689:
684:
679:
674:
669:
664:
659:
654:
649:
644:
639:
633:
631:
627:
626:
616:
615:
612:
611:
608:
607:
599:
598:
573:
567:
566:
563:
562:
554:
553:
550:
549:
547:
546:
542:
538:
534:
530:
526:
522:
518:
514:
510:
506:
503:
502:
491:
488:
487:
485:
484:
480:
476:
472:
468:
464:
460:
456:
452:
448:
444:
441:
440:
428:
427:
419:
408:
402:
401:
398:RNA expression
390:
389:
386:
385:
377:
373:
372:
364:
361:
356:
350:
349:
340:
333:
327:
323:
322:
317:
311:
310:
302:
301:
289:
288:
285:
284:
276:
272:
271:
263:
260:
255:
249:
248:
239:
232:
226:
222:
221:
214:
208:
207:
199:
198:
186:
185:
142:
138:
137:
129:
121:
120:
116:
115:
112:
111:
108:
107:
69:
68:
60:
59:
48:
42:
41:
33:
32:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
3274:
3263:
3260:
3258:
3255:
3253:
3250:
3249:
3247:
3236:
3231:
3229:
3224:
3222:
3217:
3216:
3210:
3208:
3204:
3200:
3199:chromosome 19
3196:
3191:
3188:
3184:
3179:
3168:
3167:
3163:
3161:
3160:
3156:
3154:
3153:
3149:
3148:
3146:
3142:
3136:
3135:
3131:
3129:
3128:
3124:
3123:
3121:
3117:
3111:
3110:
3106:
3103:
3099:
3098:
3093:
3089:
3085:
3081:
3077:
3074:
3070:
3067:
3066:
3065:
3064:
3060:
3058:
3057:
3053:
3052:
3050:
3046:
3040:
3039:
3035:
3033:
3032:
3028:
3026:
3025:
3021:
3019:
3018:
3014:
3012:
3011:
3007:
3003:
3002:
2998:
2996:
2995:
2991:
2990:
2989:
2986:
2984:
2983:
2979:
2977:
2976:
2972:
2970:
2969:
2965:
2960:
2957:
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2955:
2954:
2950:
2948:
2947:
2943:
2941:
2940:
2936:
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2929:
2927:
2926:
2922:
2920:
2919:
2915:
2913:
2912:
2908:
2906:
2905:
2901:
2897:
2894:
2892:
2889:
2888:
2887:
2886:
2882:
2878:
2875:
2873:
2870:
2869:
2868:
2867:
2863:
2861:
2860:
2856:
2852:
2849:
2847:
2844:
2843:
2842:
2841:
2837:
2835:
2834:
2830:
2828:
2827:
2823:
2822:
2820:
2816:
2810:
2809:
2805:
2803:
2802:
2798:
2796:
2795:
2791:
2789:
2788:
2784:
2782:
2781:
2777:
2774:
2770:
2766:
2762:
2758:
2755:
2752:
2748:
2744:
2740:
2737:
2734:
2730:
2726:
2722:
2718:
2714:
2710:
2706:
2702:
2698:
2695:
2692:
2688:
2684:
2683:
2679:
2676:
2672:
2668:
2665:
2662:
2658:
2657:
2653:
2651:
2650:
2646:
2644:
2643:
2639:
2636:
2632:
2628:
2624:
2620:
2616:
2612:
2608:
2604:
2601:
2600:
2598:
2594:
2588:
2587:
2583:
2579:
2576:
2575:
2574:
2571:
2567:
2564:
2563:
2562:
2561:
2557:
2553:
2550:
2549:
2548:
2547:
2543:
2541:
2540:
2536:
2533:
2529:
2525:
2524:
2520:
2519:
2517:
2513:
2506:
2502:
2499:
2496:
2492:
2489:
2486:
2482:
2479:
2477:
2476:
2472:
2469:
2465:
2462:
2459:
2455:
2451:
2447:
2446:
2442:
2439:
2435:
2431:
2427:
2426:
2422:
2420:
2419:
2415:
2412:
2408:
2405:
2403:
2402:
2398:
2395:
2391:
2388:
2385:
2381:
2378:
2377:
2375:
2371:
2364:
2360:
2357:
2354:
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2347:
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2344:
2340:
2337:
2333:
2330:
2328:
2327:
2323:
2321:
2320:
2316:
2314:
2313:
2309:
2307:
2306:
2302:
2300:
2299:
2295:
2292:
2288:
2284:
2280:
2276:
2272:
2268:
2267:
2263:
2261:
2260:
2256:
2254:
2253:
2249:
2246:
2242:
2238:
2235:
2232:
2228:
2224:
2221:
2218:
2214:
2210:
2209:
2205:
2202:
2198:
2195:
2194:
2192:
2188:
2182:
2179:
2177:
2174:
2172:
2169:
2167:
2164:
2162:
2159:
2157:
2154:
2152:
2149:
2147:
2144:
2142:
2139:
2137:
2134:
2132:
2129:
2127:
2124:
2123:
2121:
2117:
2111:
2108:
2106:
2103:
2101:
2098:
2096:
2093:
2091:
2088:
2087:
2085:
2082:
2077:
2071:
2068:
2066:
2063:
2061:
2058:
2056:
2053:
2051:
2048:
2046:
2043:
2041:
2038:
2036:
2033:
2031:
2028:
2026:
2023:
2021:
2018:
2016:
2013:
2011:
2008:
2006:
2003:
2001:
1998:
1996:
1993:
1992:
1990:
1986:
1980:
1977:
1975:
1972:
1970:
1967:
1965:
1962:
1961:
1959:
1955:
1950:
1946:
1942:
1938:
1931:
1926:
1924:
1919:
1917:
1912:
1911:
1908:
1894:
1888:
1883:
1879:
1873:
1868:
1864:
1858:
1853:
1849:
1843:
1838:
1834:
1828:
1823:
1819:
1813:
1808:
1804:
1798:
1793:
1789:
1780:
1775:
1773:
1768:
1766:
1761:
1760:
1757:
1748:
1744:
1739:
1734:
1730:
1726:
1725:J. Biol. Chem
1722:
1717:
1713:
1709:
1705:
1701:
1697:
1693:
1688:
1684:
1680:
1676:
1672:
1668:
1664:
1660:
1656:
1650:
1646:
1642:
1638:
1634:
1630:
1626:
1621:
1617:
1613:
1609:
1605:
1601:
1597:
1592:
1588:
1584:
1580:
1576:
1570:
1566:
1562:
1557:
1552:
1549:(5): 249–70.
1548:
1544:
1543:J. Hum. Genet
1540:
1535:
1531:
1527:
1523:
1519:
1516:(2): 416–23.
1515:
1511:
1505:
1501:
1497:
1493:
1489:
1483:
1479:
1475:
1471:
1467:
1463:
1459:
1454:
1450:
1446:
1442:
1438:
1434:
1430:
1426:
1422:
1417:
1413:
1409:
1405:
1401:
1397:
1393:
1388:
1384:
1380:
1376:
1372:
1368:
1364:
1359:
1358:
1353:
1348:
1344:
1343:
1338:
1337:
1332:
1331:
1327:
1318:
1312:
1310:
1306:
1301:
1297:
1293:
1289:
1285:
1281:
1273:
1270:
1265:
1261:
1256:
1251:
1248:(3): 651–60.
1247:
1243:
1239:
1232:
1229:
1224:
1220:
1214:
1211:
1206:
1202:
1196:
1193:
1189:
1185:
1180:
1178:
1176:
1172:
1168:
1164:
1159:
1157:
1155:
1151:
1144:
1142:
1140:
1136:
1132:
1128:
1124:
1120:
1115:
1113:
1110:
1106:
1102:
1090:
1085:
1081:
1077:
1074:
1070:
1063:
1061:
1058:
1054:
1050:
1046:
1043:
1039:
1035:
1028:
1022:
1018:
1015:
1009:
1007:
1001:
997:
994:
990:
983:
981:
975:
971:
968:
962:
960:
954:
950:
947:
945:RefSeq (mRNA)
943:
936:
935:
930:
926:
923:
917:
916:
911:
907:
904:
902:
898:
891:
890:
885:
881:
878:
872:
871:
866:
862:
859:
857:
853:
846:
845:
840:
836:
833:
827:
826:
821:
817:
814:
812:
808:
805:
802:
800:
797:
793:
790:
786:
782:
775:
771:
766:
760:
757:
755:
752:
750:
747:
745:
742:
741:
739:
736:
735:
729:
726:
724:
721:
719:
716:
714:
711:
709:
706:
704:
701:
700:
698:
695:
694:
688:
685:
683:
680:
678:
675:
673:
670:
668:
665:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
634:
632:
629:
628:
625:
624:Gene ontology
621:
617:
605:
600:
596:
589:
582:
577:
574:
572:
568:
560:
555:
544:
540:
536:
532:
528:
524:
520:
516:
512:
508:
507:
504:
500:
495:
492:
482:
478:
474:
470:
466:
462:
458:
454:
450:
446:
445:
442:
438:
433:
430:
429:
426:
424:
420:
418:
417:
413:
412:
409:
407:
403:
399:
395:
391:
383:
378:
374:
370:
365:
355:
351:
344:
337:
331:
324:
316:
312:
308:
303:
299:
294:
290:
282:
277:
273:
269:
264:
254:
250:
243:
236:
230:
223:
219:
213:
209:
205:
200:
196:
191:
187:
183:
179:
175:
171:
167:
163:
159:
155:
151:
147:
139:
134:
127:
122:
117:
106:
104:
100:
96:
92:
88:
84:
80:
76:
70:
65:
62:
61:
57:
54:
47:
43:
38:
34:
30:
25:
20:
3207:expanding it
3192:
3177:
3164:
3157:
3150:
3132:
3125:
3107:
3101:
3095:
3091:
3087:
3083:
3079:
3061:
3054:
3036:
3029:
3022:
3015:
3008:
2999:
2992:
2987:
2980:
2973:
2966:
2951:
2944:
2937:
2930:
2923:
2916:
2909:
2902:
2883:
2864:
2857:
2838:
2831:
2824:
2806:
2799:
2792:
2785:
2778:
2756:
2738:
2696:
2680:
2666:
2654:
2647:
2640:
2602:
2584:
2572:
2558:
2544:
2537:
2521:
2500:
2490:
2480:
2473:
2463:
2443:
2423:
2416:
2406:
2399:
2389:
2379:
2358:
2348:
2341:
2331:
2324:
2317:
2310:
2303:
2296:
2264:
2257:
2250:
2236:
2222:
2206:
2196:
2004:
1892:
1877:
1862:
1847:
1832:
1817:
1802:
1728:
1724:
1698:(1): 86–90.
1695:
1691:
1658:
1654:
1628:
1624:
1602:(2): 662–9.
1599:
1595:
1578:
1574:
1546:
1542:
1513:
1509:
1491:
1487:
1461:
1457:
1424:
1421:J. Mol. Evol
1420:
1395:
1391:
1366:
1362:
1341:
1335:
1283:
1279:
1272:
1245:
1241:
1231:
1222:
1213:
1204:
1195:
1116:
1108:
1100:
1099:
1024:
1003:
977:
956:
932:
913:
887:
868:
842:
823:
803:
798:
662:heme binding
517:right kidney
513:human kidney
475:frontal pole
421:
414:
141:External IDs
72:
1937:Cytochromes
1785:PDB gallery
1392:Xenobiotica
1286:(1): 1–18.
1127:cholesterol
380:26,542,973
367:26,534,730
279:41,096,195
266:41,088,451
119:Identifiers
3246:Categories
3144:CYP701-999
3119:CYP501-699
3048:CYP301-499
2818:CYP101-281
1941:oxygenases
1575:Cancer Res
1488:Cancer Res
1190:, May 2017
1169:, May 2017
1145:References
1133:and other
425:(ortholog)
162:HomoloGene
3197:on human
3152:CYP704B22
1006:NP_000757
980:NM_007812
959:NM_000766
789:Orthologs
728:cytoplasm
529:esophagus
170:GeneCards
3166:CYP720A1
3134:CYP504B1
3109:CYP318A1
3102:CYP315A1
3097:CYP314A1
3092:CYP307A2
3088:CYP307A1
3084:CYP306A1
3080:CYP302A1
3056:CYP303A1
3031:CYP199A2
3010:CYP176A1
2968:CYP154C3
2932:CYP125A1
2918:CYP119A1
2911:CYP113A1
2859:CYP106A2
2833:CYP102A1
2826:CYP101A1
2596:CYP71-99
2515:CYP51-69
2373:CYP21-49
1747:17428784
1712:15618722
1683:26225467
1675:15333516
1645:15115698
1616:15063809
1587:14633739
1565:12721789
1530:12130698
1500:11016631
1478:10353262
1449:12153961
1300:15128046
1186:–
1165:–
1131:steroids
1123:proteins
1073:Wikidata
768:Sources:
718:membrane
3038:CYP255A
3017:CYP183A
2982:CYP161C
2975:CYP158A
2808:CYP99A3
2801:CYP97C1
2794:CYP93E1
2787:CYP90C1
2780:CYP88D6
2649:CYP73A1
2642:CYP72A1
2190:CYP5-20
1441:8587134
1412:9890157
1383:7581481
1342:CYP2A13
1336:CYP2A13
1264:7668294
1255:1801261
1188:Ensembl
1167:Ensembl
1139:tobacco
1119:enzymes
1109:CYP2A13
1105:protein
901:UniProt
856:Ensembl
795:Species
774:QuickGO
400:pattern
258:19q13.2
174:CYP2A13
133:CYP2A13
126:Aliases
22:CYP2A13
3159:CYP710
3127:CYP503
3063:CYP305
3024:CYP197
2988:CYP170
2953:CYP152
2946:CYP147
2939:CYP139
2925:CYP123
2904:CYP111
2885:CYP109
2866:CYP107
2840:CYP105
2079:CYP3 (
1745:
1710:
1681:
1673:
1643:
1614:
1585:
1563:
1528:
1498:
1476:
1447:
1439:
1410:
1381:
1333:Human
1298:
1262:
1252:
1135:lipids
1059:search
1057:PubMed
934:P20852
915:Q16696
811:Entrez
571:BioGPS
537:thymus
150:608055
3201:is a
2757:CYP81
2739:CYP80
2697:CYP79
2682:CYP76
2667:CYP75
2656:CYP74
2603:CYP71
2586:CYP61
2573:CYP56
2560:CYP55
2546:CYP53
2539:CYP52
2523:CYP51
2501:CYP46
2491:CYP39
2481:CYP35
2475:CYP29
2464:CYP28
2445:CYP27
2425:CYP26
2418:CYP25
2407:CYP24
2401:CYP23
2390:CYP22
2380:CYP21
2359:CYP20
2349:CYP19
2343:CYP18
2332:CYP17
2326:CYP16
2319:CYP15
2312:CYP14
2305:CYP13
2298:CYP12
2266:CYP11
2259:CYP10
2081:CYP3A
1951:1.14)
1679:S2CID
1445:S2CID
1103:is a
844:13087
804:Mouse
799:Human
770:Amigo
525:liver
423:Mouse
416:Human
363:Start
298:Mouse
262:Start
195:Human
166:85917
158:88597
3203:stub
3195:gene
2252:CYP9
2237:CYP8
2223:CYP7
2208:CYP6
2197:CYP5
2119:CYP4
1988:CYP2
1957:CYP1
1893:2p85
1878:2fdy
1863:2fdw
1848:2fdv
1833:2fdu
1818:1z11
1803:1z10
1743:PMID
1708:PMID
1671:PMID
1641:PMID
1612:PMID
1583:PMID
1561:PMID
1526:PMID
1496:PMID
1474:PMID
1437:PMID
1408:PMID
1379:PMID
1296:PMID
1260:PMID
1112:gene
825:1553
406:Bgee
354:Band
315:Chr.
253:Band
212:Chr.
146:OMIM
103:4EJI
99:4EJH
95:4EJG
91:3T3S
87:2PG7
83:2PG6
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