244:
221:
118:
143:
3359:
250:
149:
3339:
1239:
1202:
Paulussen A, Lavrijsen K, Bohets H, Hendrickx J, Verhasselt P, Luyten W, Konings F, Armstrong M (July 2000). "Two linked mutations in transcriptional regulatory elements of the CYP3A5 gene constitute the major genetic determinant of polymorphic activity in humans".
1243:
1272:
1145:
Komori M, Nishio K, Ohi H, Kitada M, Kamataki T (February 1989). "Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450".
538:
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
1989:
1034:
gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene.
257:
156:
2454:
3400:
1258:
2038:
1276:
2210:
79:
734:
1030:
The CYP3A7 enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The
715:
2192:
2188:
1351:
2816:
1877:
2709:
2884:
2623:
2461:
2170:
1694:
1127:
1109:
3419:
2557:
2114:
2030:
2784:
2355:
2054:
1311:
243:
941:
934:
3393:
3058:
2757:
2094:
220:
2433:
2796:
2742:
2231:
2072:
1951:
1650:
1096:
1075:
2417:
2224:
3214:
1317:
1092:
142:
117:
3434:
2601:
2128:
2098:
2058:
2046:
1344:
3329:
1071:
3386:
2282:
2196:
2184:
59:
3025:
2874:
2334:
2034:
1702:
256:
155:
1329:
2616:
2217:
2156:
2152:
2140:
2136:
2132:
249:
148:
3199:
3315:
3302:
3289:
3276:
3263:
3250:
3237:
3020:
2981:
2971:
2957:
2953:
2943:
2931:
2911:
2894:
2862:
2826:
2726:
2653:
2520:
2405:
2174:
3209:
3424:
3163:
3106:
2644:
2589:
2327:
2274:
2269:
2124:
1975:
1372:
1337:
1304:
1046:
is associated with poor outcomes in some cancer patients, possibly because of the effect of the enzyme on some
779:
67:
2866:
50:, CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, cytochrome P450 family 3 subfamily A member 7, P450HLp2
3111:
2657:
2376:
2249:
760:
3005:
2921:
2670:
2203:
2148:
2144:
2110:
2042:
1624:
3132:
3051:
2801:
2774:
2609:
2440:
1946:
3204:
2916:
2879:
2640:
2398:
2295:
2166:
2065:
1706:
528:
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
131:
46:
3429:
3168:
2902:
2550:
2256:
2084:
1323:
1300:
1898:
3101:
2665:
2050:
91:
2811:
917:
896:
870:
849:
2699:
1220:
1162:
39:
3370:
1528:
3147:
3142:
3116:
3044:
1397:
1212:
1154:
1013:
336:
267:
211:
166:
87:
3194:
3178:
3091:
2789:
2499:
1368:
1158:
1020:
997:
311:
3366:
3343:
3232:
3173:
3015:
2995:
2990:
2632:
1807:
1249:"CYP3A7 cytochrome P450 family 3 subfamily A member 7 [ Homo sapiens (human) ]"
3358:
649:
644:
639:
634:
618:
613:
608:
603:
598:
582:
577:
572:
567:
562:
557:
552:
547:
542:
537:
532:
527:
3413:
3137:
3096:
2582:
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2369:
2362:
2348:
2308:
2289:
2263:
1216:
514:
3086:
2834:
2830:
2105:
2079:
1983:
1969:
1962:
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1848:
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1824:
1766:
1749:
1742:
1735:
1728:
1721:
1689:
1682:
1047:
329:
108:
71:
95:
3310:
3245:
3081:
1675:
1631:
1273:"CYP3A7*1C Allele Associated With Poor Outcomes in CLL, Breast, and Lung Cancer"
1132:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1114:
National Center for
Biotechnology Information, U.S. National Library of Medicine
3338:
412:
2966:
1360:
1024:
1001:
228:
125:
75:
1023:
members of the cytochrome P450 family in liver. They are responsible for the
3284:
3258:
2935:
2898:
2842:
2636:
2575:
1776:
1364:
679:
472:
350:
295:
282:
194:
181:
83:
1224:
1166:
981:
976:
2714:
2532:
2492:
2479:
2424:
2391:
2341:
2319:
2314:
2300:
1248:
965:
824:
805:
3010:
2001:
1928:
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1908:
1891:
1881:
1873:
1861:
1857:
1853:
1834:
1786:
1759:
1714:
1710:
1698:
1589:
1584:
1579:
1554:
1549:
1533:
1453:
1448:
1428:
791:
746:
3297:
3067:
2852:
2847:
2806:
1668:
1664:
1654:
1640:
1636:
1604:
1599:
1594:
1574:
1569:
1564:
1559:
1518:
1513:
1493:
1488:
1483:
1478:
1473:
1468:
1463:
1458:
1443:
1438:
1433:
1423:
1418:
1402:
1392:
1387:
1253:
1043:
1009:
1005:
949:
701:
1180:
3271:
2999:
2734:
2692:
2685:
2680:
2675:
1955:
1817:
1504:
664:
660:
2779:
2767:
2762:
2752:
2747:
2730:
2704:
2009:
63:
3040:
2605:
1333:
3036:
319:
3374:
3327:
484:
3223:
3187:
3156:
3125:
3074:
2980:
2952:
2930:
2893:
2861:
2825:
2725:
2652:
2567:
2542:
2471:
2241:
2019:
1938:
1796:
1613:
1542:
1502:
1411:
1380:
1019:The CYP3A group of enzymes are the most abundantly
910:
889:
863:
842:
1088:
1086:
1084:
1067:
1065:
1063:
1027:of more than 50% of all clinical pharmaceuticals.
266:
165:
1181:"Cytochrome P450, Subfamily IIIA, Polypeptide 7"
1008:. It carries out a similar role in fetuses that
16:Protein-coding gene in the species Homo sapiens
1093:GRCm38: Ensembl release 89: ENSMUSG00000029727
3394:
3052:
2617:
1345:
1259:National Center for Biotechnology Information
8:
1004:in size and shares 87% of its sequence with
1072:GRCh38: Ensembl release 89: ENSG00000160870
3401:
3387:
3059:
3045:
3037:
2624:
2610:
2602:
1352:
1338:
1330:
675:
510:
307:
206:
103:
1303:at the U.S. National Library of Medicine
609:intracellular membrane-bounded organelle
3334:
1059:
573:estrogen 16-alpha-hydroxylase activity
20:
1159:10.1093/oxfordjournals.jbchem.a122632
271:
232:
227:
170:
129:
124:
7:
3355:
3353:
2817:24-hydroxycholesterol 7α-hydroxylase
3373:. You can help Knowledge (XXG) by
907:
886:
860:
839:
815:
796:
770:
751:
725:
706:
489:
407:
345:
324:
14:
3357:
3337:
1242: This article incorporates
1237:
1217:10.1097/00008571-200007000-00005
255:
248:
242:
219:
154:
147:
141:
116:
2797:Cholesterol 7 alpha-hydroxylase
2743:Flavin-containing monooxygenase
583:estrogen 2-hydroxylase activity
996:is an enzyme belonging to the
599:endoplasmic reticulum membrane
473:More reference expression data
1:
1254:Reference Sequence collection
443:epithelium of small intestine
240:
139:
635:xenobiotic metabolic process
568:steroid hydroxylase activity
3420:Genes on human chromosome 7
3026:Deoxyhypusine monooxygenase
3451:
3352:
1322:gene details page in the
650:estrogen metabolic process
3215:Michaelis–Menten kinetics
3021:Ecdysone 20-monooxygenase
2972:Stearoyl-CoA desaturase-1
2944:Dopamine beta-hydroxylase
2912:Phenylalanine hydroxylase
1128:"Mouse PubMed Reference:"
1110:"Human PubMed Reference:"
980:
975:
971:
964:
948:
942:Chr 5: 137.89 – 137.92 Mb
929:
914:
893:
882:
867:
846:
835:
822:
818:
803:
799:
790:
777:
773:
758:
754:
745:
732:
728:
713:
709:
700:
685:
678:
674:
658:
645:steroid metabolic process
513:
509:
497:
492:
483:
470:
419:
410:
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
3107:Diffusion-limited enzyme
1305:Medical Subject Headings
935:Chr 7: 99.71 – 99.74 Mb
548:oxidoreductase activity
3006:Squalene monooxygenase
2922:Tryptophan hydroxylase
2671:HIF prolyl-hydroxylase
1244:public domain material
1012:serves in adults. The
578:monooxygenase activity
455:mucous cell of stomach
397:metanephric glomerulus
3200:Eadie–Hofstee diagram
3133:Allosteric regulation
2802:Methane monooxygenase
2775:Nitric oxide synthase
1301:CYP3A7 protein, human
619:endoplasmic reticulum
447:epithelium of stomach
3435:Oxidoreductase stubs
3210:Lineweaver–Burk plot
2917:Tyrosine hydroxylase
2641:steroid hydroxylases
1316:genome location and
273:5 G2|5 76.89 cM
234:Chromosome 5 (mouse)
132:Chromosome 7 (human)
2867:iron–sulfur protein
1324:UCSC Genome Browser
640:lipid hydroxylation
369:right lobe of liver
3169:Enzyme superfamily
3102:Enzyme promiscuity
2666:Prolyl hydroxylase
1000:family. It is 503
780:ENSMUSG00000029727
628:Biological process
604:organelle membrane
592:Cellular component
533:aromatase activity
521:Molecular function
435:left lobe of liver
361:buccal mucosa cell
96:CYP3A7 - orthologs
3382:
3381:
3325:
3324:
3034:
3033:
2700:Lysyl hydroxylase
2599:
2598:
991:
990:
987:
986:
960:
959:
925:
924:
904:
903:
878:
877:
857:
856:
831:
830:
812:
811:
786:
785:
767:
766:
741:
740:
722:
721:
670:
669:
563:metal ion binding
505:
504:
501:
500:
479:
478:
466:
465:
439:intestinal villus
404:
403:
302:
301:
201:
200:
3442:
3403:
3396:
3389:
3361:
3354:
3342:
3341:
3333:
3205:Hanes–Woolf plot
3148:Enzyme activator
3143:Enzyme inhibitor
3117:Enzyme catalysis
3061:
3054:
3047:
3038:
2626:
2619:
2612:
2603:
1371:(Most belong to
1354:
1347:
1340:
1331:
1288:
1287:
1285:
1284:
1275:. Archived from
1269:
1263:
1262:
1241:
1240:
1235:
1229:
1228:
1205:Pharmacogenetics
1199:
1193:
1192:
1190:
1188:
1177:
1171:
1170:
1142:
1136:
1135:
1124:
1118:
1117:
1106:
1100:
1090:
1079:
1069:
973:
972:
944:
937:
920:
908:
899:
887:
883:RefSeq (protein)
873:
861:
852:
840:
816:
797:
771:
752:
726:
707:
676:
543:iron ion binding
511:
490:
475:
415:
413:Top expressed in
408:
353:
351:Top expressed in
346:
325:
308:
298:
285:
274:
259:
252:
246:
235:
223:
207:
197:
184:
173:
158:
151:
145:
134:
120:
104:
98:
49:
42:
21:
3450:
3449:
3445:
3444:
3443:
3441:
3440:
3439:
3425:Cytochrome P450
3410:
3409:
3408:
3407:
3350:
3348:
3336:
3328:
3326:
3321:
3233:Oxidoreductases
3219:
3195:Enzyme kinetics
3183:
3179:List of enzymes
3152:
3121:
3092:Catalytic triad
3070:
3065:
3035:
3030:
2984:- miscellaneous
2976:
2948:
2926:
2889:
2857:
2821:
2812:14α-demethylase
2721:
2648:
2633:Oxidoreductases
2630:
2600:
2595:
2563:
2538:
2500:Halloween genes
2467:
2237:
2015:
1934:
1792:
1609:
1538:
1498:
1407:
1376:
1369:cytochrome P450
1358:
1297:
1292:
1291:
1282:
1280:
1271:
1270:
1266:
1247:
1238:
1236:
1232:
1201:
1200:
1196:
1186:
1184:
1179:
1178:
1174:
1144:
1143:
1139:
1126:
1125:
1121:
1108:
1107:
1103:
1091:
1082:
1070:
1061:
1056:
1040:
1038:Notable alleles
998:cytochrome P450
982:View/Edit Mouse
977:View/Edit Human
940:
933:
930:Location (UCSC)
916:
895:
869:
848:
761:ENSG00000160870
654:
623:
587:
471:
462:
457:
453:
449:
445:
441:
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
3448:
3446:
3438:
3437:
3432:
3427:
3422:
3412:
3411:
3406:
3405:
3398:
3391:
3383:
3380:
3379:
3367:oxidoreductase
3362:
3347:
3346:
3323:
3322:
3320:
3319:
3306:
3293:
3280:
3267:
3254:
3241:
3227:
3225:
3221:
3220:
3218:
3217:
3212:
3207:
3202:
3197:
3191:
3189:
3185:
3184:
3182:
3181:
3176:
3171:
3166:
3160:
3158:
3157:Classification
3154:
3153:
3151:
3150:
3145:
3140:
3135:
3129:
3127:
3123:
3122:
3120:
3119:
3114:
3109:
3104:
3099:
3094:
3089:
3084:
3078:
3076:
3072:
3071:
3066:
3064:
3063:
3056:
3049:
3041:
3032:
3031:
3029:
3028:
3023:
3018:
3013:
3008:
3003:
2996:Heme oxygenase
2993:
2991:Cyclooxygenase
2987:
2985:
2978:
2977:
2975:
2974:
2969:
2963:
2961:
2950:
2949:
2947:
2946:
2940:
2938:
2928:
2927:
2925:
2924:
2919:
2914:
2908:
2906:
2891:
2890:
2888:
2887:
2882:
2877:
2871:
2869:
2859:
2858:
2856:
2855:
2850:
2845:
2839:
2837:
2823:
2822:
2820:
2819:
2814:
2809:
2804:
2799:
2794:
2793:
2792:
2787:
2782:
2772:
2771:
2770:
2765:
2760:
2755:
2750:
2739:
2737:
2723:
2722:
2720:
2719:
2718:
2717:
2712:
2702:
2697:
2696:
2695:
2690:
2689:
2688:
2683:
2678:
2662:
2660:
2658:2-oxoglutarate
2650:
2649:
2631:
2629:
2628:
2621:
2614:
2606:
2597:
2596:
2594:
2593:
2586:
2579:
2571:
2569:
2565:
2564:
2562:
2561:
2554:
2546:
2544:
2540:
2539:
2537:
2536:
2529:
2497:
2496:
2495:
2483:
2475:
2473:
2469:
2468:
2466:
2465:
2458:
2451:
2444:
2437:
2430:
2429:
2428:
2421:
2409:
2402:
2395:
2388:
2387:
2386:
2383:
2373:
2366:
2359:
2352:
2345:
2338:
2331:
2324:
2323:
2322:
2317:
2305:
2304:
2303:
2298:
2286:
2279:
2278:
2277:
2272:
2260:
2253:
2245:
2243:
2239:
2238:
2236:
2235:
2228:
2221:
2214:
2207:
2200:
2178:
2160:
2118:
2102:
2088:
2076:
2069:
2062:
2023:
2021:
2017:
2016:
2014:
2013:
2006:
2005:
2004:
1994:
1993:
1992:
1980:
1979:
1978:
1966:
1959:
1942:
1940:
1936:
1935:
1933:
1932:
1922:
1912:
1902:
1895:
1885:
1865:
1845:
1838:
1828:
1821:
1811:
1800:
1798:
1794:
1793:
1791:
1790:
1780:
1770:
1763:
1753:
1746:
1739:
1732:
1725:
1718:
1686:
1679:
1672:
1658:
1644:
1628:
1617:
1615:
1611:
1610:
1608:
1607:
1602:
1597:
1592:
1587:
1582:
1577:
1572:
1567:
1562:
1557:
1552:
1546:
1544:
1540:
1539:
1537:
1536:
1531:
1526:
1521:
1516:
1510:
1508:
1500:
1499:
1497:
1496:
1491:
1486:
1481:
1476:
1471:
1466:
1461:
1456:
1451:
1446:
1441:
1436:
1431:
1426:
1421:
1415:
1413:
1409:
1408:
1406:
1405:
1400:
1395:
1390:
1384:
1382:
1378:
1377:
1359:
1357:
1356:
1349:
1342:
1334:
1328:
1327:
1308:
1296:
1295:External links
1293:
1290:
1289:
1264:
1230:
1194:
1172:
1137:
1119:
1101:
1080:
1058:
1057:
1055:
1052:
1042:The CYP3A7*1C
1039:
1036:
989:
988:
985:
984:
979:
969:
968:
962:
961:
958:
957:
955:
953:
946:
945:
938:
931:
927:
926:
923:
922:
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875:
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854:
844:
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837:
833:
832:
829:
828:
820:
819:
813:
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809:
801:
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768:
765:
764:
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755:
749:
743:
742:
739:
738:
730:
729:
723:
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719:
711:
710:
704:
698:
697:
692:
687:
683:
682:
672:
671:
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667:
656:
655:
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652:
647:
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637:
631:
629:
625:
624:
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621:
616:
611:
606:
601:
595:
593:
589:
588:
586:
585:
580:
575:
570:
565:
560:
558:oxygen binding
555:
550:
545:
540:
535:
530:
524:
522:
518:
517:
507:
506:
503:
502:
499:
498:
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477:
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468:
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440:
436:
432:
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
389:jejunal mucosa
386:
382:
378:
374:
370:
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
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146:
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128:
122:
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112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
3447:
3436:
3433:
3431:
3428:
3426:
3423:
3421:
3418:
3417:
3415:
3404:
3399:
3397:
3392:
3390:
3385:
3384:
3378:
3376:
3372:
3369:article is a
3368:
3363:
3360:
3356:
3351:
3345:
3340:
3335:
3331:
3317:
3313:
3312:
3307:
3304:
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3294:
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3287:
3286:
3281:
3278:
3274:
3273:
3268:
3265:
3261:
3260:
3255:
3252:
3248:
3247:
3242:
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3229:
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3222:
3216:
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3211:
3208:
3206:
3203:
3201:
3198:
3196:
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3192:
3190:
3186:
3180:
3177:
3175:
3174:Enzyme family
3172:
3170:
3167:
3165:
3162:
3161:
3159:
3155:
3149:
3146:
3144:
3141:
3139:
3138:Cooperativity
3136:
3134:
3131:
3130:
3128:
3124:
3118:
3115:
3113:
3110:
3108:
3105:
3103:
3100:
3098:
3097:Oxyanion hole
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3079:
3077:
3073:
3069:
3062:
3057:
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3019:
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3007:
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2968:
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2945:
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2937:
2933:
2929:
2923:
2920:
2918:
2915:
2913:
2910:
2909:
2907:
2904:
2903:BH4 dependent
2900:
2896:
2892:
2886:
2883:
2881:
2878:
2876:
2873:
2872:
2870:
2868:
2864:
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2810:
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2805:
2803:
2800:
2798:
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2716:
2713:
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2708:
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2701:
2698:
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2679:
2677:
2674:
2673:
2672:
2669:
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2661:
2659:
2655:
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2646:
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2634:
2627:
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2620:
2615:
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2608:
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2604:
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2329:
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2318:
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2299:
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2240:
2234:
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2222:
2220:
2219:
2215:
2213:
2212:
2208:
2206:
2205:
2201:
2198:
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2172:
2168:
2164:
2161:
2158:
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2138:
2134:
2130:
2126:
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2119:
2116:
2112:
2108:
2107:
2103:
2100:
2096:
2092:
2089:
2086:
2082:
2081:
2077:
2075:
2074:
2070:
2068:
2067:
2063:
2060:
2056:
2052:
2048:
2044:
2040:
2036:
2032:
2028:
2025:
2024:
2022:
2018:
2012:
2011:
2007:
2003:
2000:
1999:
1998:
1995:
1991:
1988:
1987:
1986:
1985:
1981:
1977:
1974:
1973:
1972:
1971:
1967:
1965:
1964:
1960:
1957:
1953:
1949:
1948:
1944:
1943:
1941:
1937:
1930:
1926:
1923:
1920:
1916:
1913:
1910:
1906:
1903:
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1900:
1896:
1893:
1889:
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1879:
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1871:
1870:
1866:
1863:
1859:
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1815:
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1809:
1805:
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1801:
1799:
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1764:
1761:
1757:
1754:
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1733:
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1730:
1726:
1724:
1723:
1719:
1716:
1712:
1708:
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1696:
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1612:
1606:
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1598:
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1571:
1568:
1566:
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1477:
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1472:
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1467:
1465:
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1457:
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1452:
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1432:
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1427:
1425:
1422:
1420:
1417:
1416:
1414:
1410:
1404:
1401:
1399:
1396:
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1391:
1389:
1386:
1385:
1383:
1379:
1374:
1370:
1366:
1362:
1355:
1350:
1348:
1343:
1341:
1336:
1335:
1332:
1325:
1321:
1320:
1315:
1314:
1309:
1306:
1302:
1299:
1298:
1294:
1279:on 2016-06-16
1278:
1274:
1268:
1265:
1260:
1256:
1255:
1250:
1245:
1234:
1231:
1226:
1222:
1218:
1214:
1211:(5): 415–24.
1210:
1206:
1198:
1195:
1182:
1176:
1173:
1168:
1164:
1160:
1156:
1152:
1148:
1141:
1138:
1133:
1129:
1123:
1120:
1115:
1111:
1105:
1102:
1098:
1094:
1089:
1087:
1085:
1081:
1077:
1073:
1068:
1066:
1064:
1060:
1053:
1051:
1049:
1045:
1037:
1035:
1033:
1028:
1026:
1022:
1017:
1015:
1014:gene location
1011:
1007:
1003:
999:
995:
983:
978:
974:
970:
967:
963:
956:
954:
951:
947:
943:
939:
936:
932:
928:
921:
919:
913:
909:
906:
900:
898:
892:
888:
885:
881:
874:
872:
866:
862:
859:
853:
851:
845:
841:
838:
836:RefSeq (mRNA)
834:
827:
826:
821:
817:
814:
808:
807:
802:
798:
795:
793:
789:
782:
781:
776:
772:
769:
763:
762:
757:
753:
750:
748:
744:
737:
736:
731:
727:
724:
718:
717:
712:
708:
705:
703:
699:
696:
693:
691:
688:
684:
681:
677:
673:
666:
662:
657:
651:
648:
646:
643:
641:
638:
636:
633:
632:
630:
627:
626:
620:
617:
615:
612:
610:
607:
605:
602:
600:
597:
596:
594:
591:
590:
584:
581:
579:
576:
574:
571:
569:
566:
564:
561:
559:
556:
554:
551:
549:
546:
544:
541:
539:
536:
534:
531:
529:
526:
525:
523:
520:
519:
516:
515:Gene ontology
512:
508:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
381:kidney tubule
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
3375:expanding it
3364:
3349:
3311:Translocases
3308:
3295:
3282:
3269:
3256:
3246:Transferases
3243:
3230:
3087:Binding site
2835:flavoprotein
2639:, including
2637:dioxygenases
2588:
2581:
2574:
2556:
2549:
2531:
2525:
2519:
2515:
2511:
2507:
2503:
2485:
2478:
2460:
2453:
2446:
2439:
2432:
2423:
2416:
2411:
2404:
2397:
2390:
2375:
2368:
2361:
2354:
2347:
2340:
2333:
2326:
2307:
2288:
2281:
2262:
2255:
2248:
2230:
2223:
2216:
2209:
2202:
2180:
2162:
2120:
2104:
2090:
2078:
2071:
2064:
2026:
2008:
1996:
1982:
1968:
1961:
1945:
1924:
1914:
1904:
1897:
1887:
1867:
1847:
1840:
1830:
1823:
1813:
1803:
1782:
1772:
1765:
1755:
1748:
1741:
1734:
1727:
1720:
1688:
1681:
1674:
1660:
1646:
1630:
1620:
1523:
1318:
1312:
1281:. Retrieved
1277:the original
1267:
1252:
1233:
1208:
1204:
1197:
1185:. Retrieved
1175:
1153:(2): 161–3.
1150:
1146:
1140:
1131:
1122:
1113:
1104:
1048:chemotherapy
1041:
1031:
1029:
1018:
993:
992:
915:
894:
868:
847:
823:
804:
778:
759:
733:
714:
694:
689:
553:heme binding
335:
328:
294:137,919,881
281:137,891,194
55:External IDs
18:
3082:Active site
1361:Cytochromes
1016:is 7q22.1.
1002:amino acids
459:gallbladder
385:gallbladder
193:99,735,196
180:99,705,036
33:Identifiers
3430:EC 1.14.14
3414:Categories
3285:Isomerases
3259:Hydrolases
3126:Regulation
2967:Tyrosinase
2934:: reduced
2897:: reduced
2865:: reduced
2829:: reduced
2568:CYP701-999
2543:CYP501-699
2472:CYP301-499
2242:CYP101-281
1365:oxygenases
1283:2016-03-27
1147:J. Biochem
1099:, May 2017
1078:, May 2017
1054:References
1025:metabolism
451:left colon
339:(ortholog)
76:HomoloGene
3164:EC number
2936:ascorbate
2899:pteridine
2576:CYP704B22
1187:March 14,
1021:expressed
918:NP_031845
897:NP_000756
871:NM_007819
850:NM_000765
680:Orthologs
84:GeneCards
3188:Kinetics
3112:Cofactor
3075:Activity
2590:CYP720A1
2558:CYP504B1
2533:CYP318A1
2526:CYP315A1
2521:CYP314A1
2516:CYP307A2
2512:CYP307A1
2508:CYP306A1
2504:CYP302A1
2480:CYP303A1
2455:CYP199A2
2434:CYP176A1
2392:CYP154C3
2356:CYP125A1
2342:CYP119A1
2335:CYP113A1
2283:CYP106A2
2257:CYP102A1
2250:CYP101A1
2020:CYP71-99
1939:CYP51-69
1797:CYP21-49
1225:10898111
1095:–
1074:–
1050:agents.
966:Wikidata
659:Sources:
614:membrane
423:duodenum
393:duodenum
373:testicle
3344:Biology
3298:Ligases
3068:Enzymes
2982:1.14.99
2960:: other
2954:1.14.18
2932:1.14.17
2895:1.14.16
2863:1.14.15
2827:1.14.14
2727:1.14.13
2654:1.14.11
2462:CYP255A
2441:CYP183A
2406:CYP161C
2399:CYP158A
2232:CYP99A3
2225:CYP97C1
2218:CYP93E1
2211:CYP90C1
2204:CYP88D6
2073:CYP73A1
2066:CYP72A1
1614:CYP5-20
1167:2722762
1097:Ensembl
1076:Ensembl
792:UniProt
747:Ensembl
686:Species
665:QuickGO
427:jejunum
314:pattern
40:Aliases
3330:Portal
3272:Lyases
2831:flavin
2710:ALKBH1
2583:CYP710
2551:CYP503
2487:CYP305
2448:CYP197
2412:CYP170
2377:CYP152
2370:CYP147
2363:CYP139
2349:CYP123
2328:CYP111
2309:CYP109
2290:CYP107
2264:CYP105
1503:CYP3 (
1319:CYP3A7
1313:CYP3A7
1310:Human
1307:(MeSH)
1223:
1183:. OMIM
1165:
1044:allele
1032:CYP3A7
1010:CYP3A4
1006:CYP3A4
994:CYP3A7
952:search
950:PubMed
825:Q64464
806:P24462
702:Entrez
485:BioGPS
172:7q22.1
88:CYP3A7
80:133564
64:605340
47:CYP3A7
24:CYP3A7
3365:This
3224:Types
3000:HMOX1
2735:NADPH
2693:P4HTM
2686:EGLN3
2681:EGLN2
2676:EGLN1
2647:1.14)
2181:CYP81
2163:CYP80
2121:CYP79
2106:CYP76
2091:CYP75
2080:CYP74
2027:CYP71
2010:CYP61
1997:CYP56
1984:CYP55
1970:CYP53
1963:CYP52
1947:CYP51
1925:CYP46
1915:CYP39
1905:CYP35
1899:CYP29
1888:CYP28
1869:CYP27
1849:CYP26
1842:CYP25
1831:CYP24
1825:CYP23
1814:CYP22
1804:CYP21
1783:CYP20
1773:CYP19
1767:CYP18
1756:CYP17
1750:CYP16
1743:CYP15
1736:CYP14
1729:CYP13
1722:CYP12
1690:CYP11
1683:CYP10
1505:CYP3A
1375:1.14)
1246:from
735:13113
695:Mouse
690:Human
661:Amigo
431:ileum
377:gonad
365:liver
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
72:88610
3371:stub
3316:list
3309:EC7
3303:list
3296:EC6
3290:list
3283:EC5
3277:list
3270:EC4
3264:list
3257:EC3
3251:list
3244:EC2
3238:list
3231:EC1
3016:21A2
3011:17A1
2885:11A1
2880:11B2
2875:11B1
2843:19A1
2790:NOS3
2785:NOS2
2780:NOS1
2768:FMO5
2763:FMO4
2758:FMO3
2753:FMO2
2748:FMO1
2731:NADH
2705:AlkB
1676:CYP9
1661:CYP8
1647:CYP7
1632:CYP6
1621:CYP5
1543:CYP4
1412:CYP2
1381:CYP1
1221:PMID
1189:2013
1163:PMID
716:1551
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
2853:2E1
2848:2D6
2833:or
2807:3A4
2733:or
2715:FTO
2059:BA1
2055:AV1
2051:AJ4
1590:F22
1585:F12
1580:F11
1555:A22
1550:A11
1534:A43
1529:A37
1454:C19
1449:C18
1429:A13
1213:doi
1155:doi
1151:105
493:n/a
290:End
189:End
92:OMA
68:MGI
3416::
2958:19
2729::
2656::
2645:EC
2635::
2524:,
2518:,
2514:,
2510:,
2506:,
2502:(
2493:M2
2425:B1
2418:A1
2385:B1
2382:A1
2320:E1
2315:B1
2301:G1
2296:A1
2275:D7
2270:A1
2197:E9
2195:,
2193:E7
2191:,
2189:E3
2187:,
2185:E1
2175:G2
2173:,
2171:B1
2169:,
2167:A1
2157:D4
2155:,
2153:D3
2151:,
2149:D2
2147:,
2145:D1
2143:,
2141:B3
2139:,
2137:B2
2135:,
2133:B1
2131:,
2129:A2
2127:,
2125:A1
2115:M7
2113:,
2111:B6
2099:B1
2097:,
2095:A1
2085:D1
2057:,
2053:,
2049:,
2047:Z6
2045:,
2043:C4
2041:,
2039:C3
2037:,
2035:C2
2033:,
2031:C1
2002:A1
1990:A1
1976:A1
1956:F1
1954:,
1952:A1
1929:A1
1919:A1
1909:B1
1892:A1
1882:C1
1880:,
1878:B1
1876:,
1874:A1
1862:C1
1860:,
1858:B1
1856:,
1854:A1
1835:A1
1818:A1
1808:A2
1787:A1
1777:A1
1760:A1
1715:C1
1713:,
1711:B3
1709:,
1707:B2
1705:,
1703:B1
1701:,
1699:A2
1697:,
1695:A1
1669:B1
1667:,
1665:A1
1655:B1
1653:,
1651:A1
1641:M2
1639:,
1637:G1
1625:A1
1605:Z1
1600:X1
1595:V2
1575:F8
1570:F3
1565:F2
1560:B1
1524:A7
1519:A5
1514:A4
1494:W1
1489:U1
1484:S1
1479:R1
1474:J2
1469:F1
1464:E1
1459:D6
1444:C9
1439:C8
1434:B6
1424:A7
1419:A6
1403:B1
1398:A5
1393:A2
1388:A1
1373:EC
1367::
1363:,
1257:.
1251:.
1219:.
1209:10
1207:.
1161:.
1149:.
1130:.
1112:.
1083:^
1062:^
663:/
296:bp
283:bp
195:bp
182:bp
90:;
86::
82:;
78::
74:;
70::
66:;
62::
3402:e
3395:t
3388:v
3377:.
3332::
3318:)
3314:(
3305:)
3301:(
3292:)
3288:(
3279:)
3275:(
3266:)
3262:(
3253:)
3249:(
3240:)
3236:(
3060:e
3053:t
3046:v
3002:)
2998:(
2956:-
2905:)
2901:(
2643:(
2625:e
2618:t
2611:v
2528:)
2199:)
2183:(
2177:)
2165:(
2159:)
2123:(
2117:)
2109:(
2101:)
2093:(
2087:)
2083:(
2061:)
2029:(
1958:)
1950:(
1931:)
1927:(
1921:)
1917:(
1911:)
1907:(
1894:)
1890:(
1884:)
1872:(
1864:)
1852:(
1837:)
1833:(
1820:)
1816:(
1810:)
1806:(
1789:)
1785:(
1779:)
1775:(
1762:)
1758:(
1717:)
1693:(
1671:)
1663:(
1657:)
1649:(
1643:)
1635:(
1627:)
1623:(
1507:)
1353:e
1346:t
1339:v
1326:.
1286:.
1261:.
1227:.
1215::
1191:.
1169:.
1157::
1134:.
1116:.
214:)
111:)
94::
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