301:
278:
175:
200:
559:
552:
307:
206:
1721:
1495:
Pavinato L, Delle Vedove A, Carli D, Ferrero M, Carestiato S, Howe JL, Agolini E, Coviello DA, van de Laar I, Au PY, Di
Gregorio E, Fabbiani A, Croci S, Mencarelli MA, Bruno LP, Renieri A, Veltra D, Sofocleous C, Faivre L, Mazel B, Safraou H, Denommé-Pichon AS, van Slegtenhorst MA, Giesbertz N, van
50:
1301:"Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs"
1391:"Vaccinia virus intermediate stage transcription is complemented by Ras-GTPase-activating protein SH3 domain-binding protein (G3BP) and cytoplasmic activation/proliferation-associated protein (p137) individually or as a heterodimer"
1550:
Gessler M, Klamt B, Tsaoussidou S, Ellis JA, Luzio JP (February 1996). "The gene encoding the GPI-anchored membrane protein p137GPI (M11S1) maps to human chromosome 11p13 and is highly conserved in the mouse".
1623:
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network".
314:
213:
1106:
In 2022, loss-of-function mutations of the CAPRIN1 gene were shown to result in an autosomal-dominant disorder. Patients having the newly-discovered disorder suffer from
1350:"Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins"
777:
758:
136:
1790:
1766:
1785:
1199:
1181:
300:
1024:
1017:
277:
1430:
1496:
Jaarsveld RH, Childers A, Rogers RC, Novelli A, De Rubeis S, Buxbaum JD, Scherer SW, Ferrero GB, Wirth B, Brusco A (July 2022).
1168:
1147:
199:
174:
1164:
47:
1143:
116:
313:
212:
1446:"RNG105/caprin1, an RNA granule protein for dendritic mRNA localization, is essential for long-term memory formation"
306:
205:
1759:
1219:"Identification and characterization of a novel protein (p137) which transcytoses bidirectionally in Caco-2 cells"
1582:"Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors"
1111:
822:
124:
803:
1752:
1498:"CAPRIN1 haploinsufficiency causes a neurodevelopmental disorder with language impairment, ADHD and ASD"
188:
1632:
103:
996:
992:
988:
984:
929:
925:
921:
917:
1656:
148:
1000:
963:
959:
933:
896:
892:
558:
551:
1699:
1648:
1611:
1568:
1527:
1477:
1412:
1371:
1330:
1281:
1240:
1107:
96:
40:
1736:
1444:
Nakayama K, Ohashi R, Shinoda Y, Yamazaki M, Abe M, Fujikawa A, et al. (November 2017).
1114:. Somatically, they have respiratory problems, limb/skeletal anomalies, developmental delay,
144:
1689:
1681:
1640:
1601:
1593:
1560:
1517:
1509:
1467:
1457:
1402:
1361:
1320:
1312:
1271:
1230:
1095:
393:
324:
268:
223:
1348:
Grill B, Wilson GM, Zhang KX, Wang B, Doyonnas R, Quadroni M, Schrader JW (February 2004).
368:
1636:
1522:
1497:
1694:
1669:
1472:
1445:
1325:
1300:
1606:
1581:
692:
687:
682:
677:
661:
656:
651:
646:
641:
636:
631:
626:
621:
605:
600:
1779:
1732:
1580:
de Vries H, Rüegsegger U, Hübner W, Friedlein A, Langen H, Keller W (November 2000).
587:
1299:
Solomon S, Xu Y, Wang B, David MD, Schubert P, Kennedy D, Schrader JW (March 2007).
128:
1660:
386:
165:
107:, GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI, cell cycle associated protein 1
152:
1670:"Large-scale mapping of human protein-protein interactions by mass spectrometry"
1366:
1349:
1276:
1259:
1204:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1186:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1597:
469:
285:
182:
132:
1235:
1218:
1513:
1115:
722:
529:
407:
352:
339:
251:
238:
140:
1703:
1652:
1615:
1564:
1531:
1481:
1416:
1407:
1390:
1375:
1334:
1285:
1572:
1244:
1064:
1059:
1668:
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007).
1316:
1048:
867:
848:
1644:
1462:
1685:
1119:
1080:
834:
789:
73:
69:
1032:
744:
1720:
1260:"Absence of caprin-1 results in defects in cellular proliferation"
707:
703:
1728:
1087:
120:
567:
376:
1740:
1431:"Entrez Gene: GPIAP1 GPI-anchored membrane protein 1"
541:
693:
positive regulation of dendritic spine morphogenesis
977:
952:
910:
885:
1160:
1158:
1156:
1139:
1137:
1135:
1110:, speech delay, intellectual disability, ADHD and
323:
222:
1258:Wang B, David MD, Schrader JW (October 2005).
1165:GRCm38: Ensembl release 89: ENSMUSG00000027184
1760:
688:positive regulation of dendrite morphogenesis
8:
1144:GRCh38: Ensembl release 89: ENSG00000135387
1767:
1753:
1094:RNG105) is essential for the formation of
718:
583:
364:
263:
160:
58:
1693:
1605:
1521:
1471:
1461:
1406:
1365:
1324:
1275:
1234:
1389:Katsafanas GC, Moss B (December 2004).
1131:
18:
1217:Ellis JA, Luzio JP (September 1995).
1091:
637:integral component of plasma membrane
328:
289:
284:
227:
186:
181:
7:
1717:
1715:
1395:The Journal of Biological Chemistry
1223:The Journal of Biological Chemistry
1739:. You can help Knowledge (XXG) by
974:
949:
907:
882:
858:
839:
813:
794:
768:
749:
683:negative regulation of translation
546:
464:
402:
381:
14:
1083:that in humans is encoded by the
1719:
1090:. It is suggested that Caprin1 (
557:
550:
312:
305:
299:
276:
211:
204:
198:
173:
1791:Human chromosome 11 gene stubs
1305:Molecular and Cellular Biology
568:More reference expression data
530:More reference expression data
1:
1502:Brain: A Journal of Neurology
1122:and ophthalmologic problems.
297:
196:
1786:Genes on human chromosome 11
1367:10.4049/jimmunol.172.4.2389
1277:10.4049/jimmunol.175.7.4274
450:stromal cell of endometrium
1807:
1714:
622:cytoplasmic stress granule
1674:Molecular Systems Biology
1200:"Mouse PubMed Reference:"
1182:"Human PubMed Reference:"
1063:
1058:
1054:
1047:
1031:
1025:Chr 2: 103.59 – 103.63 Mb
1012:
981:
956:
945:
914:
889:
878:
865:
861:
846:
842:
833:
820:
816:
801:
797:
788:
775:
771:
756:
752:
743:
728:
721:
717:
701:
586:
582:
565:
549:
540:
527:
516:medullary collecting duct
476:
467:
414:
405:
375:
367:
363:
346:
333:
296:
275:
266:
262:
245:
232:
195:
172:
163:
159:
114:
111:
101:
94:
89:
66:
61:
44:
39:
34:
30:
26:
21:
1598:10.1093/emboj/19.21.5895
1236:10.1074/jbc.270.35.20717
1112:autism spectrum disorder
1018:Chr 11: 34.05 – 34.1 Mb
508:internal carotid artery
504:external carotid artery
16:Protein found in humans
1565:10.1006/geno.1996.0099
1408:10.1074/jbc.M411033200
1514:10.1093/brain/awac278
1354:Journal of Immunology
1264:Journal of Immunology
1102:Clinical significance
512:mandibular prominence
189:Chromosome 11 (human)
1317:10.1128/MCB.02300-06
1116:feeding difficulties
678:cell differentiation
496:maxillary prominence
291:Chromosome 2 (mouse)
62:List of PDB id codes
35:Available structures
1645:10.1038/nature04209
1637:2005Natur.437.1173R
1463:10.7554/eLife.29677
1401:(50): 52210–52217.
1229:(35): 20717–20723.
1108:language impairment
442:epithelium of colon
430:islet of Langerhans
418:ganglionic eminence
153:CAPRIN1 - orthologs
1727:This article on a
1686:10.1038/msb4100134
823:ENSMUSG00000027184
671:Biological process
615:Cellular component
594:Molecular function
1748:
1747:
1074:
1073:
1070:
1069:
1043:
1042:
1008:
1007:
971:
970:
941:
940:
904:
903:
874:
873:
855:
854:
829:
828:
810:
809:
784:
783:
765:
764:
713:
712:
578:
577:
574:
573:
536:
535:
523:
522:
461:
460:
359:
358:
258:
257:
85:
84:
81:
80:
45:Ortholog search:
1798:
1769:
1762:
1755:
1723:
1716:
1707:
1697:
1664:
1631:(7062): 1173–8.
1619:
1609:
1592:(21): 5895–904.
1586:The EMBO Journal
1576:
1536:
1535:
1525:
1492:
1486:
1485:
1475:
1465:
1441:
1435:
1434:
1427:
1421:
1420:
1410:
1386:
1380:
1379:
1369:
1360:(4): 2389–2400.
1345:
1339:
1338:
1328:
1296:
1290:
1289:
1279:
1270:(7): 4274–4282.
1255:
1249:
1248:
1238:
1214:
1208:
1207:
1196:
1190:
1189:
1178:
1172:
1162:
1151:
1141:
1096:long-term memory
1093:
1056:
1055:
1027:
1020:
1003:
975:
966:
950:
946:RefSeq (protein)
936:
908:
899:
883:
859:
840:
814:
795:
769:
750:
719:
584:
570:
561:
554:
547:
532:
492:primitive streak
480:genital tubercle
472:
470:Top expressed in
465:
422:ventricular zone
410:
408:Top expressed in
403:
382:
365:
355:
342:
331:
316:
309:
303:
292:
280:
264:
254:
241:
230:
215:
208:
202:
191:
177:
161:
155:
106:
99:
76:
59:
53:
32:
31:
19:
1806:
1805:
1801:
1800:
1799:
1797:
1796:
1795:
1776:
1775:
1774:
1773:
1712:
1710:
1667:
1622:
1579:
1549:
1545:
1543:Further reading
1540:
1539:
1494:
1493:
1489:
1443:
1442:
1438:
1429:
1428:
1424:
1388:
1387:
1383:
1347:
1346:
1342:
1298:
1297:
1293:
1257:
1256:
1252:
1216:
1215:
1211:
1198:
1197:
1193:
1180:
1179:
1175:
1163:
1154:
1142:
1133:
1128:
1104:
1065:View/Edit Mouse
1060:View/Edit Human
1023:
1016:
1013:Location (UCSC)
999:
995:
991:
987:
983:
962:
958:
932:
928:
924:
920:
916:
895:
891:
804:ENSG00000135387
697:
666:
642:cell projection
610:
601:protein binding
566:
556:
555:
528:
519:
514:
510:
506:
502:
498:
494:
490:
486:
482:
468:
457:
452:
448:
444:
440:
436:
432:
428:
426:Achilles tendon
424:
420:
406:
350:
337:
329:
319:
318:
317:
310:
290:
267:Gene location (
249:
236:
228:
218:
217:
216:
209:
187:
164:Gene location (
115:
102:
95:
68:
46:
17:
12:
11:
5:
1804:
1802:
1794:
1793:
1788:
1778:
1777:
1772:
1771:
1764:
1757:
1749:
1746:
1745:
1724:
1709:
1708:
1665:
1620:
1577:
1546:
1544:
1541:
1538:
1537:
1508:(2): 534–548.
1487:
1436:
1422:
1381:
1340:
1311:(6): 2324–42.
1291:
1250:
1209:
1191:
1173:
1152:
1130:
1129:
1127:
1124:
1103:
1100:
1072:
1071:
1068:
1067:
1062:
1052:
1051:
1045:
1044:
1041:
1040:
1038:
1036:
1029:
1028:
1021:
1014:
1010:
1009:
1006:
1005:
979:
978:
972:
969:
968:
954:
953:
947:
943:
942:
939:
938:
912:
911:
905:
902:
901:
887:
886:
880:
876:
875:
872:
871:
863:
862:
856:
853:
852:
844:
843:
837:
831:
830:
827:
826:
818:
817:
811:
808:
807:
799:
798:
792:
786:
785:
782:
781:
773:
772:
766:
763:
762:
754:
753:
747:
741:
740:
735:
730:
726:
725:
715:
714:
711:
710:
699:
698:
696:
695:
690:
685:
680:
674:
672:
668:
667:
665:
664:
659:
654:
649:
644:
639:
634:
629:
624:
618:
616:
612:
611:
609:
608:
603:
597:
595:
591:
590:
580:
579:
576:
575:
572:
571:
563:
562:
544:
538:
537:
534:
533:
525:
524:
521:
520:
518:
517:
513:
509:
505:
501:
500:abdominal wall
497:
493:
489:
485:
484:tail of embryo
481:
477:
474:
473:
462:
459:
458:
456:
455:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
412:
411:
399:
398:
390:
379:
373:
372:
369:RNA expression
361:
360:
357:
356:
348:
344:
343:
335:
332:
327:
321:
320:
311:
304:
298:
294:
293:
288:
282:
281:
273:
272:
260:
259:
256:
255:
247:
243:
242:
234:
231:
226:
220:
219:
210:
203:
197:
193:
192:
185:
179:
178:
170:
169:
157:
156:
113:
109:
108:
100:
92:
91:
87:
86:
83:
82:
79:
78:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1803:
1792:
1789:
1787:
1784:
1783:
1781:
1770:
1765:
1763:
1758:
1756:
1751:
1750:
1744:
1742:
1738:
1734:
1733:chromosome 11
1730:
1725:
1722:
1718:
1713:
1705:
1701:
1696:
1691:
1687:
1683:
1679:
1675:
1671:
1666:
1662:
1658:
1654:
1650:
1646:
1642:
1638:
1634:
1630:
1626:
1621:
1617:
1613:
1608:
1603:
1599:
1595:
1591:
1587:
1583:
1578:
1574:
1570:
1566:
1562:
1559:(1): 169–70.
1558:
1554:
1548:
1547:
1542:
1533:
1529:
1524:
1519:
1515:
1511:
1507:
1503:
1499:
1491:
1488:
1483:
1479:
1474:
1469:
1464:
1459:
1455:
1451:
1447:
1440:
1437:
1432:
1426:
1423:
1418:
1414:
1409:
1404:
1400:
1396:
1392:
1385:
1382:
1377:
1373:
1368:
1363:
1359:
1355:
1351:
1344:
1341:
1336:
1332:
1327:
1322:
1318:
1314:
1310:
1306:
1302:
1295:
1292:
1287:
1283:
1278:
1273:
1269:
1265:
1261:
1254:
1251:
1246:
1242:
1237:
1232:
1228:
1224:
1220:
1213:
1210:
1205:
1201:
1195:
1192:
1187:
1183:
1177:
1174:
1170:
1166:
1161:
1159:
1157:
1153:
1149:
1145:
1140:
1138:
1136:
1132:
1125:
1123:
1121:
1117:
1113:
1109:
1101:
1099:
1097:
1089:
1086:
1082:
1078:
1066:
1061:
1057:
1053:
1050:
1046:
1039:
1037:
1034:
1030:
1026:
1022:
1019:
1015:
1011:
1004:
1002:
998:
994:
990:
986:
980:
976:
973:
967:
965:
961:
955:
951:
948:
944:
937:
935:
931:
927:
923:
919:
913:
909:
906:
900:
898:
894:
888:
884:
881:
879:RefSeq (mRNA)
877:
870:
869:
864:
860:
857:
851:
850:
845:
841:
838:
836:
832:
825:
824:
819:
815:
812:
806:
805:
800:
796:
793:
791:
787:
780:
779:
774:
770:
767:
761:
760:
755:
751:
748:
746:
742:
739:
736:
734:
731:
727:
724:
720:
716:
709:
705:
700:
694:
691:
689:
686:
684:
681:
679:
676:
675:
673:
670:
669:
663:
660:
658:
655:
653:
650:
648:
645:
643:
640:
638:
635:
633:
630:
628:
625:
623:
620:
619:
617:
614:
613:
607:
604:
602:
599:
598:
596:
593:
592:
589:
588:Gene ontology
585:
581:
569:
564:
560:
553:
548:
545:
543:
539:
531:
526:
515:
511:
507:
503:
499:
495:
491:
487:
483:
479:
478:
475:
471:
466:
463:
453:
449:
445:
441:
437:
433:
429:
425:
421:
417:
416:
413:
409:
404:
401:
400:
397:
395:
391:
389:
388:
384:
383:
380:
378:
374:
370:
366:
362:
354:
349:
345:
341:
336:
326:
322:
315:
308:
302:
295:
287:
283:
279:
274:
270:
265:
261:
253:
248:
244:
240:
235:
225:
221:
214:
207:
201:
194:
190:
184:
180:
176:
171:
167:
162:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
110:
105:
98:
93:
88:
77:
75:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
1741:expanding it
1726:
1711:
1677:
1673:
1628:
1624:
1589:
1585:
1556:
1552:
1505:
1501:
1490:
1453:
1449:
1439:
1425:
1398:
1394:
1384:
1357:
1353:
1343:
1308:
1304:
1294:
1267:
1263:
1253:
1226:
1222:
1212:
1203:
1194:
1185:
1176:
1105:
1084:
1076:
1075:
997:NP_001104762
993:NP_001104761
989:NP_001104760
985:NP_001104759
982:
957:
930:NM_001111292
926:NM_001111291
922:NM_001111290
918:NM_001111289
915:
890:
866:
847:
821:
802:
776:
757:
737:
732:
446:right testis
392:
385:
351:103,627,994
338:103,593,286
112:External IDs
67:
606:RNA binding
438:left testis
434:endometrium
330:2|2 E2
250:34,102,610
237:34,051,731
90:Identifiers
1780:Categories
1171:, May 2017
1150:, May 2017
1126:References
396:(ortholog)
133:HomoloGene
1731:on human
1680:(1): 89.
1001:NP_058019
964:NP_976240
960:NP_005889
934:NM_016739
897:NM_203364
893:NM_005898
723:Orthologs
652:cytoplasm
141:GeneCards
1704:17353931
1653:16189514
1616:11060040
1553:Genomics
1532:35979925
1523:10169411
1482:29157358
1417:15471883
1376:14764709
1335:17210633
1286:16177067
1167:–
1146:–
1120:seizures
1077:Caprin-1
1049:Wikidata
702:Sources:
647:membrane
627:dendrite
1695:1847948
1661:4427026
1633:Bibcode
1573:8786113
1473:5697933
1326:1820512
1245:7657653
1169:Ensembl
1148:Ensembl
1085:CAPRIN1
1081:protein
835:UniProt
790:Ensembl
729:Species
708:QuickGO
662:synapse
657:cytosol
371:pattern
145:CAPRIN1
129:1858234
104:CAPRIN1
97:Aliases
22:CAPRIN1
1702:
1692:
1659:
1651:
1625:Nature
1614:
1607:305781
1604:
1571:
1530:
1520:
1480:
1470:
1415:
1374:
1333:
1323:
1284:
1243:
1092:a.k.a.
1035:search
1033:PubMed
868:Q60865
849:Q14444
745:Entrez
632:P-body
542:BioGPS
488:ureter
121:601178
1735:is a
1657:S2CID
1450:eLife
1079:is a
778:53872
738:Mouse
733:Human
704:Amigo
454:gonad
394:Mouse
387:Human
334:Start
269:Mouse
233:Start
229:11p13
166:Human
1737:stub
1729:gene
1700:PMID
1649:PMID
1612:PMID
1569:PMID
1528:PMID
1478:PMID
1413:PMID
1372:PMID
1331:PMID
1282:PMID
1241:PMID
1088:gene
759:4076
377:Bgee
325:Band
286:Chr.
224:Band
183:Chr.
137:4310
117:OMIM
74:4WBP
70:4WBE
51:RCSB
48:PDBe
1690:PMC
1682:doi
1641:doi
1629:437
1602:PMC
1594:doi
1561:doi
1518:PMC
1510:doi
1506:146
1468:PMC
1458:doi
1403:doi
1399:279
1362:doi
1358:172
1321:PMC
1313:doi
1272:doi
1268:175
1231:doi
1227:270
347:End
246:End
149:OMA
125:MGI
41:PDB
1782::
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1155:^
1134:^
1118:,
1098:.
706:/
353:bp
340:bp
252:bp
239:bp
147:;
143::
139:;
135::
131:;
127::
123:;
119::
72:,
1768:e
1761:t
1754:v
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