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mostly made up of young, white males, in order to limit confounding factors. The original aim of the study was to determine precursors of heart disease by subjecting each participant to a series of physical exams and an 11-page questionnaire about eating and lifestyle habits, family history, and psychosocial characteristics. The results of her research found that of the males studied, those who developed coronary artery disease also had high cholesterol but not vice versa. She also found that graduates who suffered anxiety or depression as students were more likely to be fatigued and achieve lower academic standings. Thomas believed that physical diseases had genetic, environmental, psychological, and physiological components to them. This became the first longitudinal study used to determine predictors of heart disease, cancer, and suicide in youth. Prior to her retirement, Thomas published over 130 Precursors Study manuscripts in peer-reviewed journals. Future predictor studies such as the
Framingham Heart Study, the Harvard Physicians Health Study, and the national Nurses Study have used her Precursors model as a guide.
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heirlooms to donors in exchange for donations, although no one ever accepted. Prior to ending the study, she received the 1957 James D. Bruce
Memorial Award for her work in preventive medicine. In June 1970, Thomas was promoted to the rank of Full Professor, the third female to do so. She maintained this role until her retirement in 1986 at the age of 82.
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Bedell returned to Johns
Hopkins School of Medicine as a faculty member following her Harvard fellowship in 1935. She also became a married woman to Dr. Henry M. Thomas, Jr, taking his last name. By 1936, while working with mice, she discovered that sulfanilamide could interrupt and prevent rheumatic
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Bedell joined the faculty at Johns
Hopkins University in 1930 as a house officer in their department of medicine. The following year, she was promoted to assistant professor of medicine at Johns Hopkins School of Medicine where she led studies in electrocardiography. As a result of her research, she
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Longcope eventually encouraged Thomas to start an adult cardiac, where she conducted a longitudinal study of predictors of heart disease, cancer, and suicide called "the
Precursors Study." Between the years of 1948 and 1964, Thomas conducted studies on 1,337 Johns Hopkins students and graduates,
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Although the study became influential, Thomas had a difficult time maintaining its funds. She would often take less salary money or end the cohort enrollment early. Due to lack of funds, 1964 was the last cohort Thomas studied. She became desperate enough for funds that she would offer family
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84:(November 29, 1904– December 14, 1997) was an American cardiologist. She is considered a pioneer in the study of hypertension and preventive medicine. In 1970, Thomas became the
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was elected a Fellow of medicine with the
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Thomas died on
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heart disease and other infections. While working under mentor and department chair
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273:"Dr. Caroline Thomas, 93, tracked health of Hopkins medical graduating classes"
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Ogilvie, Marilyn Bailey; Harvey, Joy
Dorothy (2000).
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271:Nawrozki, Joe (December 15, 1997).
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82:Caroline Cunningham Bedell Thomas
16:American cardiologist (1904–1997)
507:Johns Hopkins University faculty
497:Scientists from Ithaca, New York
86:Johns Hopkins School of Medicine
512:Johns Hopkins University alumni
391:. The Evening Sun. June 4, 1970
247:. Changing the Face of Medicine
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88:third female full professor.
356:"On The Shoulders of Giants"
241:"Dr. Caroline Bedell Thomas"
399:– via Newspapers.com.
362:. Fall 2018. Archived from
203:portraitcollection.jhmi.edu
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389:"Hopkins Names Dr. Thomas"
131:Warfield Theobald Longcope
415:"The Study of a Lifetime"
413:Weiss, Elaine F. (2001).
304:Whelton, Paul K. (1997).
223:Ogilvie & Harvey 2000
171:"Thomas, Caroline Bedell"
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527:American women academics
315:10.1161/01.HYP.31.6.1204
199:"Caroline Bedell Thomas"
114:Herbert Spencer Jennings
110:Johns Hopkins University
92:Early life and education
517:American cardiologists
454:. pp. 1279–1280.
331:Cite journal requires
245:cfmedicine.nlm.nih.gov
112:under the guidance of
23:Caroline Bedell Thomas
452:Taylor & Francis
522:Women cardiologists
360:hopkinsmedicine.org
175:snaccooperative.org
278:The Baltimore Sun
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75:Cardiologist
492:1997 deaths
487:1904 births
481:Categories
152:References
72:Occupation
63:1997-12-15
48:1904-11-29
424:June 12,
395:June 12,
370:June 12,
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251:June 12,
104:with an
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120:Career
469:2020
456:ISBN
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337:help
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56:Died
41:Born
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