31:
214:
for the Health
Sciences. In 1999 June joined the University of Pennsylvania as a professor of molecular and cellular engineering at the University of Pennsylvania's school of medicine and investigator at the Abramson Family Cancer Research Institute, where he remains today. He is board-certified in
855:
194:
in Geneva, Switzerland, studying immunology and malaria with Dr. Paul Henri-Lambert, and completed clinical training in internal medicine and medical oncology from 1979 to 1983 at the
880:
875:
885:
714:
223:
June has been a pioneer in the field of immunotherapy, most widely known for the development of T-cell therapy for cancer. In the 1980s, his lab supported research for the
649:
520:
845:
860:
339:
231:
in humans, discovering the cells could engraft and persist in patients with HIV/AIDS for years. His work led to the development and commercialization of
750:
206:
in
Seattle from 1983 to 1986. After completing his training, he returned to Bethesda, where he founded the Immune Cell Biology Program at the
314:
210:
and was head of the department of immunology from 1990 to 1995. He was also a professor of medicine and of cell and molecular biology at the
850:
548:
569:
June, Carl H; Ledbetter, Jeffrey A; Linsley, Peter S; Thompson, Craig B (January 1990). "Role of the CD28 receptor in T-cell activation".
450:
91:
503:"Carl H. June - Faculty - About Us - Perelman School of Medicine - Perelman School of Medicine at the University of Pennsylvania"
401:
2019 - ACTS Distinguished
Investigator: Translation from Proof-of-Concept to Applicability for Widespread Clinical Practice Award
136:
865:
715:"Carl H. June is Recipient of Inaugural Maria I. New International Prize for Biomedical Research | Mount Sinai - New York"
632:
255:
171:
30:
488:
274:
211:
207:
203:
195:
131:
524:
444:
227:
molecule as the major control switch for T cells. A few years later, tested the ability to culture genetically modified
392:
159:
187:
163:
121:
71:
191:
126:
357:
2015 - Award for
Distinguished Research in the Biomedical Sciences, Association of American Medical Colleges
840:
411:
305:
289:
742:
299:
251:
1978 - Michael E. DeBakey
Scholar award for the Outstanding Medical Student, Baylor College of Medicine
870:
549:"2015 Award for Distinguished Research in the Biomedical Sciences - AAMC Awards - Initiatives - AAMC"
264:
1996 - Dexter Conrad Award, Office of Naval
Research, Navyβs highest award for Scientific Achievement
773:"BREAKTHROUGH PRIZE ANNOUNCES 2024 LAUREATES IN LIFE SCIENCES, FUNDAMENTAL PHYSICS, AND MATHEMATICS"
167:
596:
245:
199:
614:
502:
360:
2015 - E. Donnall Thomas Award
Lecture, American Society for Blood and Marrow Transplantation
586:
578:
364:
232:
198:
in
Bethesda, Maryland. June conducted postdoctoral research in transplantation biology with
183:
63:
675:
426:
320:
2014 - Steinman Award for Human
Immunology Research, American Association of Immunologists
158:
Professor in
Immunotherapy in the Department of Pathology and Laboratory Medicine at the
662:"Alliance for Cancer Gene Therapy honors cancer pioneer Dr. Carl June at April 18 Gala"
270:
2001 - Burroughs Wellcome Fund Award: visiting professor in the basic medical sciences
834:
582:
155:
728:
661:
345:
2015 - Watanabe Prize for Translational Research, Indiana University and Eli Lilly
431:
2021 - Outstanding Achievement Award, American Society of Gene & Cell Therapy
333:
381:
2017 - Distinguished Scientist Award, Association of American Cancer Institutes
814:
802:
108:
633:"Carl June named one of TIME Magazine's Most Influential People - Penn Today"
407:
2019 - The Edward Netter Leadership Award, Alliance for Cancer Gene Therapy
154:(born 1953) is an American immunologist and oncologist. He is currently the
700:
600:
825:
591:
470:
385:
279:
2002 - William Osler Award, University of Pennsylvania School of Medicine
87:
772:
803:"A "living drug" that could change the way we treat cancer | Carl June"
295:
2012 - Ernest Beutler Lecture and Prize, American Society of Hematology
615:"Penn Researchers Earn Clinical Research Achievement Awards β PR News"
285:
2005 - Federal Laboratory Award for Excellence in Technology Transfer.
404:
2019 - Harrington Prize, American Society for Clinical Investigation
351:
2015 - Debrecen Award for Molecular Medicine, University of Debrecen
329:
2014 - Taubman Prize for Excellence in Translational Medical Science
701:"Keio Medical Science Prize - Keio University Medical Science Fund"
310:
2013 - Richard V Smalley Award, Society for Immunotherapy of Cancer
489:"The American Philosophical Society Welcomes New Members for 2020"
228:
688:
348:
2015 - Lifetime Achievement Award Lecture, Miami Winter Symposium
224:
437:
2022 - Maria I. New International Prize for Biomedical Research
168:
T cell therapies for the treatment of several forms of cancers.
190:
in 1979. He spent his fourth year of medical school at the
369:
2016 - Distinguished Graduate Award, U.S. Naval Academy.
354:
2015 - AACR-CRI Lloyd J. Old Award in Cancer Immunology.
292:
for Distinguished Research in Basic and Tumor Immunology
282:
2005-09 - Bristol-Myers Squibb Freedom to Discover Award
856:
Fellows of the American Academy of Arts and Sciences
416:
2020 - Elected member American Philosophical Society
114:
104:
83:
56:
48:
40:
21:
422:2020 - Elected member National Academy of Sciences
267:1997 - Frank Brown Berry Prize in Federal Medicine
186:in 1975 and earned his medical degree in from the
475:Penn Medicine Center for Cellular Immunotherapies
323:2014 - Aubrey Evans Award / Ronald McDonald House
743:"Citation Laureates 2023_Physiology or Medicine"
440:2023 - Phacilitate Lifetime Achievement Award
419:2020 - Genome Valley Excellence Award, BioAsia
881:Fred Hutchinson Cancer Research Center people
876:Members of the American Philosophical Society
326:2014 - Karl Landsteiner Memorial Award, AABB.
8:
815:"Engineering T Cells for Cancer - Carl June"
334:Hamdan Award for Medical Research Excellence
166:. He is most well known for his research on
886:Members of the National Academy of Medicine
826:Carl June Lab at University of Pennsylvania
375:2016 - Clinical Research Achievement Award.
340:Paul Ehrlich and Ludwig Darmstaedter Prize
29:
18:
590:
753:from the original on September 19, 2023
462:
235:, the first FDA-approved cell therapy.
543:
541:
434:2022 - The Keio Medical Science Prize
388:: The Most Influential People of 2018
315:American Academy of Arts and Sciences
7:
395:in Medicine and Biomedical Research.
16:American immunologist and oncologist
451:Breakthrough Prize in Life Sciences
372:2016 - Novartis Prize in Immunology
273:2002 - Lifetime Achievement Award,
92:Breakthrough Prize in Life Sciences
846:United States Naval Academy alumni
14:
861:Baylor College of Medicine alumni
749:. Clarivate. September 19, 2023.
650:Albany Medical Center Prize 2018
215:internal medicine and oncology.
137:Naval Medical Research Institute
261:1996 - Legion of Merit, US Navy
256:American College of Physicians
172:American Philosophical Society
170:In 2020 he was elected to the
1:
275:Leukemia and Lymphoma Society
212:Uniformed Services University
208:Naval Medical Research Center
204:Fred Hutchinson Cancer Center
196:National Naval Medical Center
132:Fred Hutchinson Cancer Center
583:10.1016/0167-5699(90)90085-n
445:Clarivate Citation Laureates
378:2017 - Karnofsky Prize, ASCO
851:United States Navy officers
393:Albany Medical Center Prize
160:Perelman School of Medicine
44:1953 (age 70–71)
902:
523:. aacr.org. Archived from
188:Baylor College of Medicine
164:University of Pennsylvania
122:University of Pennsylvania
72:Baylor College of Medicine
729:"Advanced Therapy Awards"
192:World Health Organization
145:
127:World Health Organization
97:
28:
182:June graduated from the
202:and John Hansen at the
866:American immunologists
306:The Philadelphia Award
290:William B. Coley Award
300:Institute of Medicine
779:. September 14, 2023
689:Dan David Prize 2021
412:Lorraine Cross Award
398:2018 - Passano Prize
178:Education and career
809:. October 2, 2019.
777:BREAKTHROUGH PRIZE
747:Citation Laureates
619:www.uphs.upenn.edu
521:"Carl H. June, MD"
313:2014 - Elected to
298:2012 - Elected to
507:www.med.upenn.edu
246:Alpha Omega Alpha
239:Awards and honors
200:E. Donnall Thomas
149:
148:
99:Scientific career
893:
822:
810:
789:
788:
786:
784:
769:
763:
762:
760:
758:
739:
733:
732:
725:
719:
718:
711:
705:
704:
697:
691:
686:
680:
679:
672:
666:
665:
658:
652:
647:
641:
640:
639:. 24 April 2018.
629:
623:
622:
611:
605:
604:
594:
571:Immunology Today
566:
560:
559:
557:
556:
545:
536:
535:
533:
532:
517:
511:
510:
499:
493:
492:
485:
479:
478:
467:
365:John Scott Medal
248:Medical Society.
233:tisagenlecleucel
184:US Naval Academy
156:Richard W. Vague
76:
68:
64:US Naval Academy
33:
19:
901:
900:
896:
895:
894:
892:
891:
890:
831:
830:
821:. June 7, 2018.
813:
801:
798:
793:
792:
782:
780:
771:
770:
766:
756:
754:
741:
740:
736:
727:
726:
722:
713:
712:
708:
699:
698:
694:
687:
683:
676:"Dr. Carl June"
674:
673:
669:
660:
659:
655:
648:
644:
631:
630:
626:
613:
612:
608:
568:
567:
563:
554:
552:
547:
546:
539:
530:
528:
519:
518:
514:
501:
500:
496:
487:
486:
482:
469:
468:
464:
459:
427:Dan David Prize
254:1991 - Fellow,
241:
221:
180:
141:
90:
79:
74:
66:
57:Alma mater
36:
24:
17:
12:
11:
5:
899:
897:
889:
888:
883:
878:
873:
868:
863:
858:
853:
848:
843:
833:
832:
829:
828:
823:
811:
797:
796:External links
794:
791:
790:
764:
734:
720:
706:
692:
681:
667:
653:
642:
624:
606:
577:(6): 211β216.
561:
537:
512:
494:
480:
461:
460:
458:
455:
454:
453:
447:
441:
438:
435:
432:
429:
423:
420:
417:
414:
408:
405:
402:
399:
396:
389:
382:
379:
376:
373:
370:
367:
361:
358:
355:
352:
349:
346:
343:
336:
330:
327:
324:
321:
318:
311:
308:
302:
296:
293:
286:
283:
280:
277:
271:
268:
265:
262:
259:
252:
249:
240:
237:
220:
217:
179:
176:
147:
146:
143:
142:
140:
139:
134:
129:
124:
118:
116:
112:
111:
106:
102:
101:
95:
94:
85:
81:
80:
78:
77:
69:
60:
58:
54:
53:
50:
46:
45:
42:
38:
37:
34:
26:
25:
22:
15:
13:
10:
9:
6:
4:
3:
2:
898:
887:
884:
882:
879:
877:
874:
872:
869:
867:
864:
862:
859:
857:
854:
852:
849:
847:
844:
842:
841:Living people
839:
838:
836:
827:
824:
820:
816:
812:
808:
804:
800:
799:
795:
783:September 14,
778:
774:
768:
765:
757:September 19,
752:
748:
744:
738:
735:
730:
724:
721:
716:
710:
707:
702:
696:
693:
690:
685:
682:
677:
671:
668:
663:
657:
654:
651:
646:
643:
638:
634:
628:
625:
620:
616:
610:
607:
602:
598:
593:
592:2027.42/28838
588:
584:
580:
576:
572:
565:
562:
550:
544:
542:
538:
527:on 2019-10-31
526:
522:
516:
513:
508:
504:
498:
495:
490:
484:
481:
476:
472:
466:
463:
456:
452:
448:
446:
442:
439:
436:
433:
430:
428:
424:
421:
418:
415:
413:
409:
406:
403:
400:
397:
394:
390:
387:
383:
380:
377:
374:
371:
368:
366:
362:
359:
356:
353:
350:
347:
344:
341:
337:
335:
331:
328:
325:
322:
319:
316:
312:
309:
307:
303:
301:
297:
294:
291:
287:
284:
281:
278:
276:
272:
269:
266:
263:
260:
257:
253:
250:
247:
243:
242:
238:
236:
234:
230:
226:
218:
216:
213:
209:
205:
201:
197:
193:
189:
185:
177:
175:
173:
169:
165:
161:
157:
153:
144:
138:
135:
133:
130:
128:
125:
123:
120:
119:
117:
113:
110:
107:
103:
100:
96:
93:
89:
86:
82:
73:
70:
65:
62:
61:
59:
55:
51:
47:
43:
39:
32:
27:
20:
818:
806:
781:. Retrieved
776:
767:
755:. Retrieved
746:
737:
723:
709:
695:
684:
670:
656:
645:
636:
627:
618:
609:
574:
570:
564:
553:. Retrieved
529:. Retrieved
525:the original
515:
506:
497:
483:
474:
465:
222:
181:
152:Carl H. June
151:
150:
115:Institutions
98:
67:(B.S., 1975)
35:June in 2015
23:Carl H. June
871:1953 births
75:M.D., 1979)
49:Nationality
835:Categories
555:2016-12-05
551:. aamc.org
531:2016-12-05
471:"June Lab"
457:References
109:Immunology
637:PennToday
751:Archived
386:Time 100
219:Research
88:Time 100
52:American
819:YouTube
807:YouTube
601:2162180
449:2024 -
443:2023 -
425:2021 -
410:2020 -
391:2018 -
384:2018 -
363:2016 -
338:2015 -
332:2014 -
304:2013 -
288:2012 -
244:1978 -
162:of the
599:
229:CAR-Ts
105:Fields
84:Awards
785:2023
759:2023
597:PMID
225:CD28
41:Born
587:hdl
579:doi
837::
817:.
805:.
775:.
745:.
635:.
617:.
595:.
585:.
575:11
573:.
540:^
505:.
473:.
174:.
787:.
761:.
731:.
717:.
703:.
678:.
664:.
621:.
603:.
589::
581::
558:.
534:.
509:.
491:.
477:.
342:.
317:.
258:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.