Knowledge (XXG)

Carl H. June

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for the Health Sciences. In 1999 June joined the University of Pennsylvania as a professor of molecular and cellular engineering at the University of Pennsylvania's school of medicine and investigator at the Abramson Family Cancer Research Institute, where he remains today. He is board-certified in
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in Geneva, Switzerland, studying immunology and malaria with Dr. Paul Henri-Lambert, and completed clinical training in internal medicine and medical oncology from 1979 to 1983 at the
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June has been a pioneer in the field of immunotherapy, most widely known for the development of T-cell therapy for cancer. In the 1980s, his lab supported research for the
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in humans, discovering the cells could engraft and persist in patients with HIV/AIDS for years. His work led to the development and commercialization of
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in Seattle from 1983 to 1986. After completing his training, he returned to Bethesda, where he founded the Immune Cell Biology Program at the
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and was head of the department of immunology from 1990 to 1995. He was also a professor of medicine and of cell and molecular biology at the
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June, Carl H; Ledbetter, Jeffrey A; Linsley, Peter S; Thompson, Craig B (January 1990). "Role of the CD28 receptor in T-cell activation".
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2019 - ACTS Distinguished Investigator: Translation from Proof-of-Concept to Applicability for Widespread Clinical Practice Award
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molecule as the major control switch for T cells. A few years later, tested the ability to culture genetically modified
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2015 - Award for Distinguished Research in the Biomedical Sciences, Association of American Medical Colleges
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1978 - Michael E. DeBakey Scholar award for the Outstanding Medical Student, Baylor College of Medicine
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1996 - Dexter Conrad Award, Office of Naval Research, Navy’s highest award for Scientific Achievement
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2015 - E. Donnall Thomas Award Lecture, American Society for Blood and Marrow Transplantation
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in Bethesda, Maryland. June conducted postdoctoral research in transplantation biology with
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2014 - Steinman Award for Human Immunology Research, American Association of Immunologists
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Professor in Immunotherapy in the Department of Pathology and Laboratory Medicine at the
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2001 - Burroughs Wellcome Fund Award: visiting professor in the basic medical sciences
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2015 - Watanabe Prize for Translational Research, Indiana University and Eli Lilly
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2021 - Outstanding Achievement Award, American Society of Gene & Cell Therapy
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2017 - Distinguished Scientist Award, Association of American Cancer Institutes
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2019 - The Edward Netter Leadership Award, Alliance for Cancer Gene Therapy
154:(born 1953) is an American immunologist and oncologist. He is currently the 700: 600: 825: 591: 470: 385: 279:
2002 - William Osler Award, University of Pennsylvania School of Medicine
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2012 - Ernest Beutler Lecture and Prize, American Society of Hematology
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2005 - Federal Laboratory Award for Excellence in Technology Transfer.
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2019 - Harrington Prize, American Society for Clinical Investigation
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2015 - Debrecen Award for Molecular Medicine, University of Debrecen
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2014 - Taubman Prize for Excellence in Translational Medical Science
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2013 - Richard V Smalley Award, Society for Immunotherapy of Cancer
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2015 - Lifetime Achievement Award Lecture, Miami Winter Symposium
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2022 - Maria I. New International Prize for Biomedical Research
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T cell therapies for the treatment of several forms of cancers.
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in 1979. He spent his fourth year of medical school at the
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2016 - Distinguished Graduate Award, U.S. Naval Academy.
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2015 - AACR-CRI Lloyd J. Old Award in Cancer Immunology.
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for Distinguished Research in Basic and Tumor Immunology
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2005-09 - Bristol-Myers Squibb Freedom to Discover Award
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Fellows of the American Academy of Arts and Sciences
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2020 - Elected member American Philosophical Society
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He is most well known for his research on 886:Members of the National Academy of Medicine 826:Carl June Lab at University of Pennsylvania 375:2016 - Clinical Research Achievement Award. 340:Paul Ehrlich and Ludwig Darmstaedter Prize 29: 18: 590: 753:from the original on September 19, 2023 462: 235:, the first FDA-approved cell therapy. 543: 541: 434:2022 - The Keio Medical Science Prize 388:: The Most Influential People of 2018 315:American Academy of Arts and Sciences 7: 395:in Medicine and Biomedical Research. 16:American immunologist and oncologist 451:Breakthrough Prize in Life Sciences 372:2016 - Novartis Prize in Immunology 273:2002 - Lifetime Achievement Award, 92:Breakthrough Prize in Life Sciences 846:United States Naval Academy alumni 14: 861:Baylor College of Medicine alumni 749:. Clarivate. September 19, 2023. 650:Albany Medical Center Prize 2018 215:internal medicine and oncology. 137:Naval Medical Research Institute 261:1996 - Legion of Merit, US Navy 256:American College of Physicians 172:American Philosophical Society 170:In 2020 he was elected to the 1: 275:Leukemia and Lymphoma Society 212:Uniformed Services University 208:Naval Medical Research Center 204:Fred Hutchinson Cancer Center 196:National Naval Medical Center 132:Fred Hutchinson Cancer Center 583:10.1016/0167-5699(90)90085-n 445:Clarivate Citation Laureates 378:2017 - Karnofsky Prize, ASCO 851:United States Navy officers 393:Albany Medical Center Prize 160:Perelman School of Medicine 44:1953 (age 70–71) 902: 523:. aacr.org. Archived from 188:Baylor College of Medicine 164:University of Pennsylvania 122:University of Pennsylvania 72:Baylor College of Medicine 729:"Advanced Therapy Awards" 192:World Health Organization 145: 127:World Health Organization 97: 28: 182:June graduated from the 202:and John Hansen at the 866:American immunologists 306:The Philadelphia Award 290:William B. Coley Award 300:Institute of Medicine 779:. September 14, 2023 689:Dan David Prize 2021 412:Lorraine Cross Award 398:2018 - Passano Prize 178:Education and career 809:. October 2, 2019. 777:BREAKTHROUGH PRIZE 747:Citation Laureates 619:www.uphs.upenn.edu 521:"Carl H. June, MD" 313:2014 - Elected to 298:2012 - Elected to 507:www.med.upenn.edu 246:Alpha Omega Alpha 239:Awards and honors 200:E. Donnall Thomas 149: 148: 99:Scientific career 893: 822: 810: 789: 788: 786: 784: 769: 763: 762: 760: 758: 739: 733: 732: 725: 719: 718: 711: 705: 704: 697: 691: 686: 680: 679: 672: 666: 665: 658: 652: 647: 641: 640: 639:. 24 April 2018. 629: 623: 622: 611: 605: 604: 594: 571:Immunology Today 566: 560: 559: 557: 556: 545: 536: 535: 533: 532: 517: 511: 510: 499: 493: 492: 485: 479: 478: 467: 365:John Scott Medal 248:Medical Society. 233:tisagenlecleucel 184:US Naval Academy 156:Richard W. Vague 76: 68: 64:US Naval Academy 33: 19: 901: 900: 896: 895: 894: 892: 891: 890: 831: 830: 821:. June 7, 2018. 813: 801: 798: 793: 792: 782: 780: 771: 770: 766: 756: 754: 741: 740: 736: 727: 726: 722: 713: 712: 708: 699: 698: 694: 687: 683: 676:"Dr. Carl June" 674: 673: 669: 660: 659: 655: 648: 644: 631: 630: 626: 613: 612: 608: 568: 567: 563: 554: 552: 547: 546: 539: 530: 528: 519: 518: 514: 501: 500: 496: 487: 486: 482: 469: 468: 464: 459: 427:Dan David Prize 254:1991 - Fellow, 241: 221: 180: 141: 90: 79: 74: 66: 57:Alma mater 36: 24: 17: 12: 11: 5: 899: 897: 889: 888: 883: 878: 873: 868: 863: 858: 853: 848: 843: 833: 832: 829: 828: 823: 811: 797: 796:External links 794: 791: 790: 764: 734: 720: 706: 692: 681: 667: 653: 642: 624: 606: 577:(6): 211–216. 561: 537: 512: 494: 480: 461: 460: 458: 455: 454: 453: 447: 441: 438: 435: 432: 429: 423: 420: 417: 414: 408: 405: 402: 399: 396: 389: 382: 379: 376: 373: 370: 367: 361: 358: 355: 352: 349: 346: 343: 336: 330: 327: 324: 321: 318: 311: 308: 302: 296: 293: 286: 283: 280: 277: 271: 268: 265: 262: 259: 252: 249: 240: 237: 220: 217: 179: 176: 147: 146: 143: 142: 140: 139: 134: 129: 124: 118: 116: 112: 111: 106: 102: 101: 95: 94: 85: 81: 80: 78: 77: 69: 60: 58: 54: 53: 50: 46: 45: 42: 38: 37: 34: 26: 25: 22: 15: 13: 10: 9: 6: 4: 3: 2: 898: 887: 884: 882: 879: 877: 874: 872: 869: 867: 864: 862: 859: 857: 854: 852: 849: 847: 844: 842: 841:Living people 839: 838: 836: 827: 824: 820: 816: 812: 808: 804: 800: 799: 795: 783:September 14, 778: 774: 768: 765: 757:September 19, 752: 748: 744: 738: 735: 730: 724: 721: 716: 710: 707: 702: 696: 693: 690: 685: 682: 677: 671: 668: 663: 657: 654: 651: 646: 643: 638: 634: 628: 625: 620: 616: 610: 607: 602: 598: 593: 592:2027.42/28838 588: 584: 580: 576: 572: 565: 562: 550: 544: 542: 538: 527:on 2019-10-31 526: 522: 516: 513: 508: 504: 498: 495: 490: 484: 481: 476: 472: 466: 463: 456: 452: 448: 446: 442: 439: 436: 433: 430: 428: 424: 421: 418: 415: 413: 409: 406: 403: 400: 397: 394: 390: 387: 383: 380: 377: 374: 371: 368: 366: 362: 359: 356: 353: 350: 347: 344: 341: 337: 335: 331: 328: 325: 322: 319: 316: 312: 309: 307: 303: 301: 297: 294: 291: 287: 284: 281: 278: 276: 272: 269: 266: 263: 260: 257: 253: 250: 247: 243: 242: 238: 236: 234: 230: 226: 218: 216: 213: 209: 205: 201: 197: 193: 189: 185: 177: 175: 173: 169: 165: 161: 157: 153: 144: 138: 135: 133: 130: 128: 125: 123: 120: 119: 117: 113: 110: 107: 103: 100: 96: 93: 89: 86: 82: 73: 70: 65: 62: 61: 59: 55: 51: 47: 43: 39: 32: 27: 20: 818: 806: 781:. Retrieved 776: 767: 755:. Retrieved 746: 737: 723: 709: 695: 684: 670: 656: 645: 636: 627: 618: 609: 574: 570: 564: 553:. Retrieved 529:. Retrieved 525:the original 515: 506: 497: 483: 474: 465: 222: 181: 152:Carl H. June 151: 150: 115:Institutions 98: 67:(B.S., 1975) 35:June in 2015 23:Carl H. June 871:1953 births 75:M.D., 1979) 49:Nationality 835:Categories 555:2016-12-05 551:. aamc.org 531:2016-12-05 471:"June Lab" 457:References 109:Immunology 637:PennToday 751:Archived 386:Time 100 219:Research 88:Time 100 52:American 819:YouTube 807:YouTube 601:2162180 449:2024 - 443:2023 - 425:2021 - 410:2020 - 391:2018 - 384:2018 - 363:2016 - 338:2015 - 332:2014 - 304:2013 - 288:2012 - 244:1978 - 162:of the 599:  229:CAR-Ts 105:Fields 84:Awards 785:2023 759:2023 597:PMID 225:CD28 41:Born 587:hdl 579:doi 837:: 817:. 805:. 775:. 745:. 635:. 617:. 595:. 585:. 575:11 573:. 540:^ 505:. 473:. 174:. 787:. 761:. 731:. 717:. 703:. 678:. 664:. 621:. 603:. 589:: 581:: 558:. 534:. 509:. 491:. 477:. 342:. 317:. 258:.

Index


US Naval Academy
Baylor College of Medicine
Time 100
Breakthrough Prize in Life Sciences
Immunology
University of Pennsylvania
World Health Organization
Fred Hutchinson Cancer Center
Naval Medical Research Institute
Richard W. Vague
Perelman School of Medicine
University of Pennsylvania
T cell therapies for the treatment of several forms of cancers.
American Philosophical Society
US Naval Academy
Baylor College of Medicine
World Health Organization
National Naval Medical Center
E. Donnall Thomas
Fred Hutchinson Cancer Center
Naval Medical Research Center
Uniformed Services University
CD28
CAR-Ts
tisagenlecleucel
Alpha Omega Alpha
American College of Physicians
Leukemia and Lymphoma Society
William B. Coley Award

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