Knowledge (XXG)

Centromere protein E

Source πŸ“

304: 281: 178: 203: 2287: 555: 310: 209: 31: 2847: 57: 1372:
Testa JR, Zhou JY, Bell DW, Yen TJ (Mar 1995). "Chromosomal localization of the genes encoding the kinetochore proteins CENPE and CENPF to human chromosomes 4q24β†’q25 and 1q32β†’q41, respectively, by fluorescence in situ hybridization".
2003:
Garcia-Saez I, Blot D, Kahn R, Kozielski F (2005). "Crystallization and preliminary crystallographic analysis of the motor domain of human kinetochore-associated protein CENP-E using an automated crystallization procedure".
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Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation".
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Cooke CA, Schaar B, Yen TJ, Earnshaw WC (1998). "Localization of CENP-E in the fibrous corona and outer plate of mammalian kinetochores from prometaphase through anaphase".
317: 216: 2286: 2327: 923: 139: 904: 2916: 1354: 2892: 2816: 2457: 2266: 1336: 2911: 2821: 1796:"Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules" 1454:
Yen TJ, Li G, Schaar BT, Szilak I, Cleveland DW (1992). "CENP-E is a putative kinetochore motor that accumulates just before mitosis".
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Garcia-Saez I, Yen T, Wade RH, Kozielski F (2004). "Crystal structure of the motor domain of the human kinetochore protein CENP-E".
1710:"Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1" 280: 1411: 1323: 1302: 2035:"Gene silencing of CENP-E by small interfering RNA in HeLa cells leads to missegregation of chromosomes after a mitotic delay" 1319: 202: 177: 54: 2442: 1298: 2313: 1249:
result in autosomal recessive primary microcephaly type 13, which includes skeletal abnormalities and immunodeficiency.
119: 1753:"Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC" 1234:. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation. 316: 215: 1831:"Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype" 309: 208: 2885: 2589: 2259: 2643: 2427: 968: 127: 949: 2596: 2579: 2549: 2522: 1667:"Active MAP kinase in mitosis: localization at kinetochores and association with the motor protein CENP-E" 1501:"CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase" 2584: 2482: 2878: 2804: 2714: 2544: 2492: 2467: 2407: 2252: 2204: 2107:"Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation" 1842: 1463: 191: 1882:"Identification and characterization of the potential promoter regions of 1031 kinds of human genes" 106: 2472: 1089: 1038: 1925:"Human MPS1 kinase is required for mitotic arrest induced by the loss of CENP-E from kinetochores" 1991: 1868: 1653: 1616: 1487: 151: 1114: 1093: 1063: 1042: 2534: 2446: 2232: 2179: 2136: 2093: 2064: 2021: 1983: 1954: 1911: 1860: 1817: 1782: 1739: 1696: 1645: 1608: 1573: 1530: 1479: 1390: 99: 47: 2862: 1587:"CENP-E is a plus end-directed kinetochore motor required for metaphase chromosome alignment" 2724: 2623: 2222: 2212: 2169: 2161: 2126: 2118: 2085: 2054: 2046: 2013: 1975: 1944: 1936: 1901: 1893: 1850: 1807: 1772: 1764: 1729: 1721: 1686: 1678: 1637: 1598: 1563: 1555: 1520: 1512: 1471: 1382: 396: 327: 271: 226: 2779: 2774: 554: 147: 2616: 2437: 2385: 371: 1226:
of the cell cycle. Unlike other centromere-associated proteins, it is not present during
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Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, et al. (1991).
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Suzuki Y, Tsunoda T, Sese J, Taira H, Mizushima-Sugano J, Hata H, et al. (2001).
1855: 1830: 1603: 1586: 1568: 1543: 1525: 1500: 838: 833: 828: 823: 818: 813: 808: 803: 798: 793: 788: 783: 778: 773: 768: 763: 758: 753: 748: 732: 727: 722: 717: 712: 707: 702: 697: 692: 687: 682: 677: 672: 667: 662: 657: 652: 647: 642: 626: 621: 616: 611: 606: 601: 596: 2905: 2487: 2150:"Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling" 1544:"Mitotic HeLa cells contain a CENP-E-associated minus end-directed microtubule motor" 1219: 583: 1995: 1872: 1657: 1620: 131: 2858: 2462: 2336: 1491: 1231: 389: 168: 1665:
Zecevic M, Catling AD, Eblen ST, Renzi L, Hittle JC, Yen TJ, et al. (1998).
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antigen processing and presentation of exogenous peptide antigen via MHC class II
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Uren AG, Wong L, Pakusch M, Fowler KJ, Burrows FJ, Vaux DL, et al. (2001).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
1426:"OMIM Entry - # 616051 - MICROCEPHALY 13, PRIMARY, AUTOSOMAL RECESSIVE; MCPH13" 472: 2701: 2691: 2686: 2671: 2611: 2601: 2502: 2477: 2451: 2402: 2392: 2340: 2089: 2017: 1227: 1211: 288: 185: 135: 2122: 1794:
Ashar HR, James L, Gray K, Carr D, Black S, Armstrong L, et al. (2000).
2653: 2397: 2375: 2356: 2305: 2217: 2050: 868: 532: 410: 355: 342: 254: 241: 143: 2295:: Crystal structure of the motor domain of human kinetochore protein CENP-E 2236: 2183: 2140: 2097: 2068: 2033:
Tanudji M, Shoemaker J, L'Italien L, Russell L, Chin G, Schebye XM (2005).
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retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
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Kurasawa Y, Earnshaw WC, Mochizuki Y, Dohmae N, Todokoro K (2005).
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and first appears at the centromere region of chromosomes during
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lateral attachment of mitotic spindle microtubules to kinetochore
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Nousiainen M, SilljΓ© HH, Sauer G, Nigg EA, KΓΆrner R (2006).
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Liu ST, Chan GK, Hittle JC, Fujii G, Lees E, Yen TJ (2003).
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Chan GK, Jablonski SA, Sudakin V, Hittle JC, Yen TJ (1999).
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Thrower DA, Jordan MA, Schaar BT, Yen TJ, Wilson L (1995).
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microtubule plus-end directed mitotic chromosome migration
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attachment of mitotic spindle microtubules to kinetochore
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Wood KW, Sakowicz R, Goldstein LS, Cleveland DW (1997).
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International System for Human Cytogenetic Nomenclature
2193:"Phosphoproteome analysis of the human mitotic spindle" 110:, CENP-E, KIF10, PPP1R61, MCPH13, Centromere protein E 544: 2797: 2700: 2662: 2632: 2560: 2416: 2347: 1107: 1082: 1056: 1031: 749:
regulation of mitotic metaphase/anaphase transition
1315: 1313: 1311: 1294: 1292: 1290: 1412:"Entrez Gene: CENPE centromere protein E, 312kDa" 326: 225: 819:mitotic chromosome movement towards spindle pole 1320:GRCm38: Ensembl release 89: ENSMUSG00000045328 759:positive regulation of protein kinase activity 16:Centromere- and microtubule-associated protein 2886: 2321: 2260: 8: 1299:GRCh38: Ensembl release 89: ENSG00000138778 2893: 2879: 2659: 2328: 2314: 2306: 2267: 2253: 2245: 864: 579: 367: 266: 163: 65: 2226: 2216: 2173: 2130: 2058: 1948: 1905: 1854: 1811: 1776: 1733: 1690: 1602: 1567: 1524: 1406: 1404: 693:condensed chromosome, centromeric region 2282: 1286: 20: 2817:List of organisms by chromosome count 2148:Mao Y, Desai A, Cleveland DW (2005). 331: 292: 287: 230: 189: 184: 7: 2843: 2841: 1708:Chan GK, Schaar BT, Yen TJ (1998). 834:mitotic metaphase plate congression 2865:. You can help Knowledge (XXG) by 1560:10.1002/j.1460-2075.1995.tb07073.x 1517:10.1002/j.1460-2075.1991.tb08066.x 1104: 1079: 1053: 1028: 1004: 985: 959: 940: 914: 895: 764:multicellular organism development 549: 467: 405: 384: 14: 2845: 2285: 1237:CENPE is also called Kinesin-7. 553: 315: 308: 302: 279: 214: 207: 201: 176: 29: 2438:Macrochromosome/Microchromosome 1191:Centromere-associated protein E 668:chromosome, centromeric region 564:More reference expression data 533:More reference expression data 1: 2917:Human chromosome 4 gene stubs 1856:10.1016/S0960-9822(00)00769-7 1604:10.1016/S0092-8674(00)80419-5 300: 199: 2197:Proc. Natl. Acad. Sci. U.S.A 814:mitotic spindle organization 2912:Genes on human chromosome 4 1214:-associated protein E is a 799:metaphase plate congression 453:stromal cell of endometrium 2933: 2840: 2478:Dinoflagellate chromosomes 784:microtubule-based movement 617:microtubule motor activity 2822:List of sequenced genomes 2590:Chromosomal translocation 2463:A chromosome/B chromosome 2454:(or accessory chromosome) 2280: 2090:10.1016/j.jmb.2004.05.053 2018:10.1107/S0907444904009564 1355:"Mouse PubMed Reference:" 1337:"Human PubMed Reference:" 1177: 1172: 1168: 1161: 1145: 1139:Chr 3: 134.92 – 134.98 Mb 1126: 1111: 1086: 1075: 1060: 1035: 1024: 1011: 1007: 992: 988: 979: 966: 962: 947: 943: 934: 921: 917: 902: 898: 889: 874: 867: 863: 847: 789:sister chromatid cohesion 582: 578: 561: 552: 543: 530: 479: 470: 417: 408: 378: 370: 366: 349: 336: 299: 278: 269: 265: 248: 235: 198: 175: 166: 162: 117: 114: 104: 97: 92: 73: 68: 51: 46: 41: 37: 28: 23: 2644:Telomere-binding protein 2458:Supernumerary chromosome 2123:10.1038/sj.emboj.7600347 1222:that accumulates in the 1132:Chr 4: 103.11 – 103.2 Mb 698:microtubule cytoskeleton 2218:10.1073/pnas.0507066103 2051:10.1091/mbc.E03-07-0482 723:kinetochore microtubule 703:mitotic spindle midzone 2580:Structural alterations 1941:10.1091/mbc.02-05-0074 1813:10.1074/jbc.M003469200 1683:10.1083/jcb.142.6.1547 1387:10.1006/geno.1994.1558 829:chromosome segregation 2597:Numerical alterations 2585:Chromosomal inversion 2483:Homologous chromosome 2166:10.1083/jcb.200505040 1769:10.1083/jcb.146.5.941 1642:10.1007/s004120050266 1241:Clinical significance 511:mandibular prominence 2805:Extrachromosomal DNA 2493:Satellite chromosome 2468:Lampbrush chromosome 2408:Nuclear organization 1726:10.1083/jcb.143.1.49 779:kinetochore assembly 499:maxillary prominence 333:3 G3|3 62.55 cM 294:Chromosome 3 (mouse) 192:Chromosome 4 (human) 69:List of PDB id codes 42:Available structures 2498:Centromere position 2473:Polytene chromosome 2443:Circular chromosome 2209:2006PNAS..103.5391N 2006:Acta Crystallogr. D 1898:10.1101/gr.gr-1640r 1847:2000CBio...10.1319U 1468:1992Natur.359..536Y 627:kinetochore binding 622:microtubule binding 437:ganglionic eminence 2853:This article on a 1201:is encoded by the 969:ENSMUSG00000045328 809:mitotic cell cycle 742:Biological process 636:Cellular component 597:nucleotide binding 590:Molecular function 2874: 2873: 2835: 2834: 2793: 2792: 2530:Centromere number 2447:Linear chromosome 2303: 2302: 2012:(Pt 6): 1158–60. 1188: 1187: 1184: 1183: 1157: 1156: 1122: 1121: 1101: 1100: 1071: 1070: 1050: 1049: 1020: 1019: 1001: 1000: 975: 974: 956: 955: 930: 929: 911: 910: 859: 858: 663:outer kinetochore 574: 573: 570: 569: 539: 538: 526: 525: 464: 463: 457:bone marrow cells 362: 361: 261: 260: 156:CENPE - orthologs 88: 87: 84: 83: 52:Ortholog search: 2924: 2895: 2888: 2881: 2849: 2842: 2660: 2624:Polyploidization 2452:Extra chromosome 2367:Genetic material 2330: 2323: 2316: 2307: 2289: 2269: 2262: 2255: 2246: 2240: 2230: 2220: 2187: 2177: 2144: 2134: 2101: 2072: 2062: 2029: 1999: 1962: 1952: 1919: 1909: 1876: 1858: 1825: 1815: 1790: 1780: 1747: 1737: 1704: 1694: 1661: 1624: 1606: 1581: 1571: 1538: 1528: 1495: 1476:10.1038/359536a0 1440: 1439: 1437: 1436: 1422: 1416: 1415: 1408: 1399: 1398: 1369: 1363: 1362: 1351: 1345: 1344: 1333: 1327: 1317: 1306: 1296: 1170: 1169: 1141: 1134: 1117: 1105: 1096: 1080: 1076:RefSeq (protein) 1066: 1054: 1045: 1029: 1005: 986: 960: 941: 915: 896: 865: 580: 566: 557: 550: 535: 503:ventricular zone 491:genital tubercle 487:secondary oocyte 475: 473:Top expressed in 468: 433:secondary oocyte 425:ventricular zone 413: 411:Top expressed in 406: 385: 368: 358: 345: 334: 319: 312: 306: 295: 283: 267: 257: 244: 233: 218: 211: 205: 194: 180: 164: 158: 109: 102: 79: 66: 60: 39: 38: 33: 21: 2932: 2931: 2927: 2926: 2925: 2923: 2922: 2921: 2902: 2901: 2900: 2899: 2838: 2836: 2831: 2789: 2696: 2658: 2628: 2617:Paleopolyploidy 2562: 2556: 2412: 2386:Heterochromatin 2349: 2343: 2334: 2304: 2299: 2296: 2290: 2276: 2273: 2243: 2190: 2147: 2117:(16): 3237–48. 2104: 2075: 2039:Mol. Biol. Cell 2032: 2002: 1968:Nat. Biotechnol 1965: 1929:Mol. Biol. Cell 1922: 1879: 1841:(21): 1319–28. 1828: 1806:(39): 30451–7. 1793: 1750: 1707: 1664: 1627: 1584: 1541: 1498: 1462:(6395): 536–9. 1453: 1449: 1447:Further reading 1444: 1443: 1434: 1432: 1424: 1423: 1419: 1410: 1409: 1402: 1371: 1370: 1366: 1353: 1352: 1348: 1335: 1334: 1330: 1318: 1309: 1297: 1288: 1283: 1255: 1243: 1179:View/Edit Mouse 1174:View/Edit Human 1137: 1130: 1127:Location (UCSC) 1113: 1092: 1088: 1062: 1041: 1037: 950:ENSG00000138778 843: 737: 733:spindle midzone 648:kinesin complex 631: 612:protein binding 602:ATPase activity 562: 531: 522: 517: 513: 509: 505: 501: 497: 493: 489: 485: 471: 460: 455: 451: 447: 445:trabecular bone 443: 439: 435: 431: 427: 423: 409: 353: 340: 332: 322: 321: 320: 313: 293: 270:Gene location ( 252: 239: 231: 221: 220: 219: 212: 190: 167:Gene location ( 118: 105: 98: 75: 53: 17: 12: 11: 5: 2930: 2928: 2920: 2919: 2914: 2904: 2903: 2898: 2897: 2890: 2883: 2875: 2872: 2871: 2850: 2833: 2832: 2830: 2829: 2824: 2819: 2814: 2813: 2812: 2801: 2799: 2795: 2794: 2791: 2790: 2788: 2787: 2782: 2777: 2772: 2767: 2762: 2757: 2752: 2747: 2742: 2737: 2732: 2727: 2722: 2717: 2712: 2706: 2704: 2698: 2697: 2695: 2694: 2689: 2684: 2679: 2674: 2668: 2666: 2657: 2656: 2651: 2636: 2634: 2630: 2629: 2627: 2626: 2621: 2620: 2619: 2614: 2609: 2604: 2594: 2593: 2592: 2587: 2577: 2572: 2566: 2564: 2558: 2557: 2555: 2554: 2553: 2552: 2547: 2542: 2537: 2527: 2526: 2525: 2520: 2515: 2510: 2508:Submetacentric 2505: 2495: 2490: 2485: 2480: 2475: 2470: 2465: 2460: 2455: 2449: 2440: 2435: 2434:or heterosome) 2428:Sex chromosome 2420: 2418: 2414: 2413: 2411: 2410: 2405: 2400: 2395: 2390: 2389: 2388: 2383: 2373: 2364: 2359: 2353: 2351: 2345: 2344: 2335: 2333: 2332: 2325: 2318: 2310: 2301: 2300: 2298: 2297: 2291: 2284: 2281: 2278: 2277: 2274: 2272: 2271: 2264: 2257: 2249: 2242: 2241: 2203:(14): 5391–6. 2188: 2145: 2102: 2084:(5): 1107–16. 2073: 2045:(8): 3771–81. 2030: 2000: 1980:10.1038/nbt971 1963: 1935:(4): 1638–51. 1920: 1877: 1826: 1791: 1748: 1705: 1677:(6): 1547–58. 1662: 1625: 1582: 1539: 1511:(5): 1245–54. 1496: 1450: 1448: 1445: 1442: 1441: 1417: 1400: 1364: 1346: 1328: 1307: 1285: 1284: 1282: 1279: 1278: 1277: 1270: 1263: 1254: 1251: 1242: 1239: 1186: 1185: 1182: 1181: 1176: 1166: 1165: 1159: 1158: 1155: 1154: 1152: 1150: 1143: 1142: 1135: 1128: 1124: 1123: 1120: 1119: 1109: 1108: 1102: 1099: 1098: 1084: 1083: 1077: 1073: 1072: 1069: 1068: 1058: 1057: 1051: 1048: 1047: 1033: 1032: 1026: 1022: 1021: 1018: 1017: 1009: 1008: 1002: 999: 998: 990: 989: 983: 977: 976: 973: 972: 964: 963: 957: 954: 953: 945: 944: 938: 932: 931: 928: 927: 919: 918: 912: 909: 908: 900: 899: 893: 887: 886: 881: 876: 872: 871: 861: 860: 857: 856: 845: 844: 842: 841: 836: 831: 826: 821: 816: 811: 806: 801: 796: 791: 786: 781: 776: 771: 766: 761: 756: 751: 745: 743: 739: 738: 736: 735: 730: 725: 720: 715: 710: 705: 700: 695: 690: 685: 680: 675: 670: 665: 660: 655: 650: 645: 639: 637: 633: 632: 630: 629: 624: 619: 614: 609: 604: 599: 593: 591: 587: 586: 576: 575: 572: 571: 568: 567: 559: 558: 547: 541: 540: 537: 536: 528: 527: 524: 523: 521: 520: 516: 515:abdominal wall 512: 508: 507:primary oocyte 504: 500: 496: 495:tail of embryo 492: 488: 484: 480: 477: 476: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 426: 422: 418: 415: 414: 402: 401: 393: 382: 376: 375: 372:RNA expression 364: 363: 360: 359: 351: 347: 346: 338: 335: 330: 324: 323: 314: 307: 301: 297: 296: 291: 285: 284: 276: 275: 263: 262: 259: 258: 250: 246: 245: 237: 234: 229: 223: 222: 213: 206: 200: 196: 195: 188: 182: 181: 173: 172: 160: 159: 116: 112: 111: 103: 95: 94: 90: 89: 86: 85: 82: 81: 71: 70: 62: 61: 50: 44: 43: 35: 34: 26: 25: 15: 13: 10: 9: 6: 4: 3: 2: 2929: 2918: 2915: 2913: 2910: 2909: 2907: 2896: 2891: 2889: 2884: 2882: 2877: 2876: 2870: 2868: 2864: 2860: 2856: 2851: 2848: 2844: 2839: 2828: 2825: 2823: 2820: 2818: 2815: 2811: 2808: 2807: 2806: 2803: 2802: 2800: 2796: 2786: 2783: 2781: 2778: 2776: 2773: 2771: 2768: 2766: 2763: 2761: 2758: 2756: 2753: 2751: 2748: 2746: 2743: 2741: 2738: 2736: 2733: 2731: 2728: 2726: 2723: 2721: 2718: 2716: 2713: 2711: 2708: 2707: 2705: 2703: 2699: 2693: 2690: 2688: 2685: 2683: 2680: 2678: 2675: 2673: 2670: 2669: 2667: 2665: 2661: 2655: 2652: 2649: 2645: 2641: 2638: 2637: 2635: 2631: 2625: 2622: 2618: 2615: 2613: 2610: 2608: 2605: 2603: 2600: 2599: 2598: 2595: 2591: 2588: 2586: 2583: 2582: 2581: 2578: 2576: 2573: 2571: 2568: 2567: 2565: 2563:and evolution 2559: 2551: 2548: 2546: 2543: 2541: 2538: 2536: 2533: 2532: 2531: 2528: 2524: 2521: 2519: 2516: 2514: 2511: 2509: 2506: 2504: 2501: 2500: 2499: 2496: 2494: 2491: 2489: 2488:Isochromosome 2486: 2484: 2481: 2479: 2476: 2474: 2471: 2469: 2466: 2464: 2461: 2459: 2456: 2453: 2450: 2448: 2444: 2441: 2439: 2436: 2433: 2429: 2425: 2422: 2421: 2419: 2415: 2409: 2406: 2404: 2401: 2399: 2396: 2394: 2391: 2387: 2384: 2382: 2379: 2378: 2377: 2374: 2372: 2368: 2365: 2363: 2360: 2358: 2355: 2354: 2352: 2346: 2342: 2338: 2331: 2326: 2324: 2319: 2317: 2312: 2311: 2308: 2294: 2288: 2283: 2279: 2270: 2265: 2263: 2258: 2256: 2251: 2250: 2247: 2238: 2234: 2229: 2224: 2219: 2214: 2210: 2206: 2202: 2198: 2194: 2189: 2185: 2181: 2176: 2171: 2167: 2163: 2160:(6): 873–80. 2159: 2155: 2151: 2146: 2142: 2138: 2133: 2128: 2124: 2120: 2116: 2112: 2108: 2103: 2099: 2095: 2091: 2087: 2083: 2079: 2074: 2070: 2066: 2061: 2056: 2052: 2048: 2044: 2040: 2036: 2031: 2027: 2023: 2019: 2015: 2011: 2007: 2001: 1997: 1993: 1989: 1985: 1981: 1977: 1974:(6): 707–16. 1973: 1969: 1964: 1960: 1956: 1951: 1946: 1942: 1938: 1934: 1930: 1926: 1921: 1917: 1913: 1908: 1903: 1899: 1895: 1892:(5): 677–84. 1891: 1887: 1883: 1878: 1874: 1870: 1866: 1862: 1857: 1852: 1848: 1844: 1840: 1836: 1832: 1827: 1823: 1819: 1814: 1809: 1805: 1801: 1800:J. Biol. Chem 1797: 1792: 1788: 1784: 1779: 1774: 1770: 1766: 1763:(5): 941–54. 1762: 1758: 1754: 1749: 1745: 1741: 1736: 1731: 1727: 1723: 1719: 1715: 1711: 1706: 1702: 1698: 1693: 1688: 1684: 1680: 1676: 1672: 1668: 1663: 1659: 1655: 1651: 1647: 1643: 1639: 1636:(7): 446–55. 1635: 1631: 1626: 1622: 1618: 1614: 1610: 1605: 1600: 1597:(3): 357–66. 1596: 1592: 1588: 1583: 1579: 1575: 1570: 1565: 1561: 1557: 1554:(5): 918–26. 1553: 1549: 1545: 1540: 1536: 1532: 1527: 1522: 1518: 1514: 1510: 1506: 1502: 1497: 1493: 1489: 1485: 1481: 1477: 1473: 1469: 1465: 1461: 1457: 1452: 1451: 1446: 1431: 1427: 1421: 1418: 1413: 1407: 1405: 1401: 1396: 1392: 1388: 1384: 1380: 1376: 1368: 1365: 1360: 1356: 1350: 1347: 1342: 1338: 1332: 1329: 1325: 1321: 1316: 1314: 1312: 1308: 1304: 1300: 1295: 1293: 1291: 1287: 1280: 1276: 1275: 1271: 1269: 1268: 1264: 1262: 1261: 1257: 1256: 1252: 1250: 1248: 1245:Mutations in 1240: 1238: 1235: 1233: 1229: 1225: 1221: 1220:motor protein 1217: 1213: 1209: 1207: 1204: 1200: 1196: 1192: 1180: 1175: 1171: 1167: 1164: 1160: 1153: 1151: 1148: 1144: 1140: 1136: 1133: 1129: 1125: 1118: 1116: 1110: 1106: 1103: 1097: 1095: 1091: 1085: 1081: 1078: 1074: 1067: 1065: 1059: 1055: 1052: 1046: 1044: 1040: 1034: 1030: 1027: 1025:RefSeq (mRNA) 1023: 1016: 1015: 1010: 1006: 1003: 997: 996: 991: 987: 984: 982: 978: 971: 970: 965: 961: 958: 952: 951: 946: 942: 939: 937: 933: 926: 925: 920: 916: 913: 907: 906: 901: 897: 894: 892: 888: 885: 882: 880: 877: 873: 870: 866: 862: 855: 851: 846: 840: 837: 835: 832: 830: 827: 825: 822: 820: 817: 815: 812: 810: 807: 805: 802: 800: 797: 795: 792: 790: 787: 785: 782: 780: 777: 775: 772: 770: 769:cell division 767: 765: 762: 760: 757: 755: 752: 750: 747: 746: 744: 741: 740: 734: 731: 729: 726: 724: 721: 719: 716: 714: 711: 709: 706: 704: 701: 699: 696: 694: 691: 689: 686: 684: 681: 679: 676: 674: 671: 669: 666: 664: 661: 659: 656: 654: 651: 649: 646: 644: 641: 640: 638: 635: 634: 628: 625: 623: 620: 618: 615: 613: 610: 608: 605: 603: 600: 598: 595: 594: 592: 589: 588: 585: 584:Gene ontology 581: 577: 565: 560: 556: 551: 548: 546: 542: 534: 529: 518: 514: 510: 506: 502: 498: 494: 490: 486: 482: 481: 478: 474: 469: 466: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 403: 400: 398: 394: 392: 391: 387: 386: 383: 381: 377: 373: 369: 365: 357: 352: 348: 344: 339: 329: 325: 318: 311: 305: 298: 290: 286: 282: 277: 273: 268: 264: 256: 251: 247: 243: 238: 228: 224: 217: 210: 204: 197: 193: 187: 183: 179: 174: 170: 165: 161: 157: 153: 149: 145: 141: 137: 133: 129: 125: 121: 113: 108: 101: 96: 91: 80: 78: 72: 67: 64: 63: 59: 56: 49: 45: 40: 36: 32: 27: 22: 19: 2867:expanding it 2859:chromosome 4 2852: 2837: 2729: 2529: 2497: 2337:Cytogenetics 2292: 2200: 2196: 2157: 2154:J. Cell Biol 2153: 2114: 2110: 2081: 2078:J. Mol. Biol 2077: 2042: 2038: 2009: 2005: 1971: 1967: 1932: 1928: 1889: 1885: 1838: 1834: 1803: 1799: 1760: 1757:J. Cell Biol 1756: 1720:(1): 49–63. 1717: 1714:J. Cell Biol 1713: 1674: 1671:J. Cell Biol 1670: 1633: 1629: 1594: 1590: 1551: 1547: 1508: 1504: 1459: 1455: 1433:. Retrieved 1430:www.omim.org 1429: 1420: 1381:(3): 691–3. 1378: 1374: 1367: 1358: 1349: 1340: 1331: 1272: 1265: 1258: 1246: 1244: 1236: 1232:prometaphase 1210: 1202: 1190: 1189: 1112: 1090:NP_001273663 1087: 1061: 1039:NM_001286734 1036: 1012: 993: 967: 948: 922: 903: 883: 878: 708:cytoskeleton 519:vas deferens 395: 388: 354:134,979,372 341:134,918,298 253:103,198,445 240:103,105,349 115:External IDs 74: 18: 2550:Polycentric 2540:Monocentric 2523:Holocentric 2518:Acrocentric 2513:Telocentric 2503:Metacentric 2381:Euchromatin 2341:chromosomes 2275:PDB gallery 728:nucleoplasm 688:kinetochore 683:microtubule 607:ATP binding 449:bone marrow 93:Identifiers 2906:Categories 2702:Centromere 2633:Structures 2612:Polyploidy 2602:Aneuploidy 2403:Nucleosome 2393:Chromosome 1886:Genome Res 1835:Curr. Biol 1630:Chromosoma 1435:2020-01-25 1326:, May 2017 1305:, May 2017 1281:References 1228:interphase 1212:Centromere 754:cell cycle 653:chromosome 399:(ortholog) 136:HomoloGene 2857:on human 2654:Protamine 2561:Processes 2545:Dicentric 2398:Chromatid 2376:Chromatin 2357:Karyotype 1115:NP_776123 1094:NP_001804 1064:NM_173762 1043:NM_001813 869:Orthologs 713:cytoplasm 144:GeneCards 2798:See also 2640:Telomere 2607:Euploidy 2535:Acentric 2432:allosome 2424:Autosome 2350:concepts 2237:16565220 2184:16144904 2141:15297875 2098:15236970 2069:15181147 2026:15159587 1996:27764390 1988:15146197 1959:12686615 1916:11337467 1873:18455745 1865:11084331 1822:10852915 1787:10477750 1658:18884489 1621:12216144 1375:Genomics 1322:– 1301:– 1253:See also 1224:G2 phase 1197:that in 1163:Wikidata 848:Sources: 673:membrane 429:testicle 2810:Plasmid 2664:Histone 2575:Meiosis 2570:Mitosis 2228:1459365 2205:Bibcode 2175:2171436 1843:Bibcode 1778:2169490 1744:9763420 1735:2132809 1701:9744883 1692:2141767 1650:9391217 1613:9363944 1578:7889940 1535:2022189 1492:4306312 1484:1406971 1464:Bibcode 1395:7851898 1324:Ensembl 1303:Ensembl 1216:kinesin 1195:protein 981:UniProt 936:Ensembl 875:Species 854:QuickGO 718:cytosol 678:midbody 658:nucleus 643:spindle 374:pattern 132:1098230 100:Aliases 2371:Genome 2362:Ploidy 2235:  2225:  2182:  2172:  2139:  2132:514520 2129:  2111:EMBO J 2096:  2067:  2060:491836 2057:  2024:  1994:  1986:  1957:  1950:153128 1947:  1914:  1907:311086 1904:  1871:  1863:  1820:  1785:  1775:  1742:  1732:  1699:  1689:  1656:  1648:  1619:  1611:  1576:  1569:398164 1566:  1548:EMBO J 1533:  1526:452779 1523:  1505:EMBO J 1490:  1482:  1456:Nature 1393:  1218:-like 1199:humans 1149:search 1147:PubMed 1014:Q6RT24 995:Q02224 924:229841 891:Entrez 545:BioGPS 483:zygote 421:oocyte 124:117143 2861:is a 2648:TINF2 2417:Types 2348:Basic 1992:S2CID 1869:S2CID 1654:S2CID 1617:S2CID 1488:S2CID 1274:CENPT 1267:CENPJ 1260:CENPF 1247:CENPE 1203:CENPE 1193:is a 884:Mouse 879:Human 850:Amigo 441:gonad 397:Mouse 390:Human 337:Start 272:Mouse 236:Start 169:Human 148:CENPE 140:20429 107:CENPE 24:CENPE 2863:stub 2855:gene 2430:(or 2293:1t5c 2233:PMID 2180:PMID 2137:PMID 2094:PMID 2065:PMID 2022:PMID 1984:PMID 1955:PMID 1912:PMID 1861:PMID 1818:PMID 1783:PMID 1740:PMID 1697:PMID 1646:PMID 1609:PMID 1591:Cell 1574:PMID 1531:PMID 1480:PMID 1391:PMID 1206:gene 905:1062 380:Bgee 328:Band 289:Chr. 232:4q24 227:Band 186:Chr. 120:OMIM 77:1T5C 58:RCSB 55:PDBe 2682:H2B 2677:H2A 2223:PMC 2213:doi 2201:103 2170:PMC 2162:doi 2158:170 2127:PMC 2119:doi 2086:doi 2082:340 2055:PMC 2047:doi 2014:doi 1976:doi 1945:PMC 1937:doi 1902:PMC 1894:doi 1851:doi 1808:doi 1804:275 1773:PMC 1765:doi 1761:146 1730:PMC 1722:doi 1718:143 1687:PMC 1679:doi 1675:142 1638:doi 1634:106 1599:doi 1564:PMC 1556:doi 1521:PMC 1513:doi 1472:doi 1460:359 1383:doi 350:End 249:End 152:OMA 128:MGI 48:PDB 2908:: 2725:C2 2720:C1 2692:H4 2687:H3 2672:H1 2642:: 2339:: 2231:. 2221:. 2211:. 2199:. 2195:. 2178:. 2168:. 2156:. 2152:. 2135:. 2125:. 2115:23 2113:. 2109:. 2092:. 2080:. 2063:. 2053:. 2043:15 2041:. 2037:. 2020:. 2010:60 2008:. 1990:. 1982:. 1972:22 1970:. 1953:. 1943:. 1933:14 1931:. 1927:. 1910:. 1900:. 1890:11 1888:. 1884:. 1867:. 1859:. 1849:. 1839:10 1837:. 1833:. 1816:. 1802:. 1798:. 1781:. 1771:. 1759:. 1755:. 1738:. 1728:. 1716:. 1712:. 1695:. 1685:. 1673:. 1669:. 1652:. 1644:. 1632:. 1615:. 1607:. 1595:91 1593:. 1589:. 1572:. 1562:. 1552:14 1550:. 1546:. 1529:. 1519:. 1509:10 1507:. 1503:. 1486:. 1478:. 1470:. 1458:. 1428:. 1403:^ 1389:. 1379:23 1377:. 1357:. 1339:. 1310:^ 1289:^ 1208:. 852:/ 356:bp 343:bp 255:bp 242:bp 150:; 146:: 142:; 138:: 134:; 130:: 126:; 122:: 2894:e 2887:t 2880:v 2869:. 2785:T 2780:Q 2775:P 2770:O 2765:N 2760:M 2755:K 2750:J 2745:I 2740:H 2735:F 2730:E 2715:B 2710:A 2650:) 2646:( 2445:/ 2426:/ 2369:/ 2329:e 2322:t 2315:v 2268:e 2261:t 2254:v 2239:. 2215:: 2207:: 2186:. 2164:: 2143:. 2121:: 2100:. 2088:: 2071:. 2049:: 2028:. 2016:: 1998:. 1978:: 1961:. 1939:: 1918:. 1896:: 1875:. 1853:: 1845:: 1824:. 1810:: 1789:. 1767:: 1746:. 1724:: 1703:. 1681:: 1660:. 1640:: 1623:. 1601:: 1580:. 1558:: 1537:. 1515:: 1494:. 1474:: 1466:: 1438:. 1414:. 1397:. 1385:: 1361:. 1343:. 274:) 171:) 154::

Index


PDB
PDBe
RCSB
1T5C
Aliases
CENPE
OMIM
117143
MGI
1098230
HomoloGene
20429
GeneCards
CENPE
OMA
CENPE - orthologs
Human
Chromosome 4 (human)
Chr.
Chromosome 4 (human)
Chromosome 4 (human)
Genomic location for CENPE
Genomic location for CENPE
Band
bp
bp
Mouse
Chromosome 3 (mouse)
Chr.

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