Knowledge (XXG)

Choline chloride

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Choline chloride is mass-produced with world production estimated at 160 000 tons in 1999. Industrially, it is produced by the reaction of
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Matthias Frauenkron; Johann-Peter Melder; Günther Ruider; Roland Rossbacher; Hartmut Höke (2002). "Ethanolamines and Propanolamines".
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functional group. The anion of this salt, choline, occurs in nature in living beings. Choline chloride is a white, water-soluble
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title=Johnson Matthey Process Technology - Choline chloride licensed process
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Screening Information Data Set (SIDS) for High Production Volume Chemicals
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Except where otherwise noted, data are given for materials in their
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InChI=1S/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
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InChI=1/C5H14NO.ClH/c1-6(2,3)4-5-7;/h7H,4-5H2,1-3H3;1H/q+1;/p-1
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It is also used as a clay control additive in fluids used for
288: 518: 592: 223: 806:It is an important additive in feed especially for 437:302 °C (576 °F; 575 K) (decomposes) 853:. In foodstuffs, the compound is often present as 250: 1008:Kirk-Othmer encyclopedia of chemical technology 522: 107: 925:Ullmann's Encyclopedia of Industrial Chemistry 751:Choline chloride can also be made by treating 712:In the laboratory, choline can be prepared by 8: 303: 213: 191: 74:(2-Hydroxyethyl)trimethylammonium chloride 15: 918: 916: 270: 810:where it accelerates growth. It forms a 793: 789: 785: 781: 777: 773: 769: 765: 669: 665: 661: 657: 638: 634: 630: 626: 397: 393: 389: 385: 866: 359: 324: 299: 689:compound, meaning, it contains both a 204: 331:Key: SGMZJAMFUVOLNK-UHFFFAOYSA-M 171: 151: 7: 341:Key: SGMZJAMFUVOLNK-REWHXWOFAH 241: 62:-trimethylethan-1-aminium chloride 14: 743: 582: 31: 22: 739:, or from the pre-formed salt: 578:(at 25 °C , 100 kPa). 461:Occupational safety and health 1: 1068:Quaternary ammonium compounds 1006:Kirk RE, et al. (2000). 826:, and many other compounds. 704:used mainly in animal feed. 449:very soluble (>650 g/L) 1089: 1032:"What Chemicals Are Used" 572: 480: 458: 453: 370: 350: 315: 91: 68: 44: 39: 30: 21: 933:10.1002/14356007.a10_001 645:quaternary ammonium salt 927:. Weinheim: Wiley-VCH. 529: 231:(additional chemicals) 812:deep eutectic solvent 528: 831:hydraulic fracturing 718:dimethylethanolamine 511:(fire diamond) 46:Preferred IUPAC name 855:phosphatidylcholine 691:quaternary ammonium 444:Solubility in water 415: g·mol 18: 968:"Choline chloride" 851:choline bitartrate 605:Infobox references 530: 16: 847:choline hydroxide 841:Other commercial 733:hydrogen chloride 623:with the formula 613:Chemical compound 611: 610: 561:Safety data sheet 284:CompTox Dashboard 133:Interactive image 17:Choline chloride 1080: 1073:Primary alcohols 1052: 1051: 1049: 1047: 1038:. Archived from 1028: 1022: 1021: 1003: 997: 996: 994: 993: 987: 981:. Archived from 972: 964: 958: 953: 947: 946: 920: 911: 910: 908: 906: 895: 889: 888: 886: 880:. Archived from 879: 871: 797: 747: 694:functional group 684: 673: 647:, consisting of 642: 621:organic compound 617:Choline chloride 595: 589: 586: 585: 550: 543: 536: 521: 414: 401: 378:Chemical formula 308: 307: 292: 290: 274: 254: 243: 225: 217: 206: 195: 175: 155: 135: 111: 35: 26: 19: 1088: 1087: 1083: 1082: 1081: 1079: 1078: 1077: 1058: 1057: 1056: 1055: 1045: 1043: 1030: 1029: 1025: 1018: 1005: 1004: 1000: 991: 989: 985: 970: 966: 965: 961: 954: 950: 943: 922: 921: 914: 904: 902: 897: 896: 892: 884: 877: 873: 872: 868: 863: 839: 820:ethylene glycol 804: 795: 791: 787: 783: 779: 775: 771: 767: 763: 757:2-chloroethanol 722:methyl chloride 710: 682: 671: 667: 663: 659: 655: 640: 636: 632: 628: 624: 614: 607: 602: 601: 600:  ?) 591: 587: 583: 579: 555: 554: 553: 552: 545: 538: 531: 527: 519: 496: 471: 446: 412: 399: 395: 391: 387: 383: 380: 366: 363: 358: 357: 346: 343: 342: 339: 333: 332: 329: 323: 322: 311: 293: 286: 277: 257: 244: 198: 178: 158: 138: 125: 114: 101: 87: 86: 64: 63: 12: 11: 5: 1086: 1084: 1076: 1075: 1070: 1060: 1059: 1054: 1053: 1042:on 2 July 2020 1023: 1016: 998: 959: 948: 941: 912: 890: 887:on 2017-07-12. 865: 864: 862: 859: 838: 835: 803: 800: 799: 798: 753:trimethylamine 749: 748: 737:trimethylamine 729:ethylene oxide 709: 706: 612: 609: 608: 603: 581: 580: 576:standard state 573: 570: 569: 564: 557: 556: 546: 539: 532: 517: 516: 515: 514: 512: 503: 502: 497: 492: 489: 488: 478: 477: 472: 469: 466: 465: 456: 455: 451: 450: 447: 442: 439: 438: 435: 429: 428: 421: 417: 416: 410: 404: 403: 381: 376: 373: 372: 368: 367: 365: 364: 361: 353: 352: 351: 348: 347: 345: 344: 340: 337: 336: 334: 330: 327: 326: 318: 317: 316: 313: 312: 310: 309: 296: 294: 282: 279: 278: 276: 275: 267: 265: 259: 258: 256: 255: 247: 245: 237: 234: 233: 227: 219: 218: 208: 200: 199: 197: 196: 188: 186: 180: 179: 177: 176: 168: 166: 160: 159: 157: 156: 148: 146: 140: 139: 137: 136: 128: 126: 119: 116: 115: 113: 112: 104: 102: 97: 94: 93: 89: 88: 85: 84: 81: 78: 75: 71: 70: 66: 65: 49: 48: 42: 41: 37: 36: 28: 27: 13: 10: 9: 6: 4: 3: 2: 1085: 1074: 1071: 1069: 1066: 1065: 1063: 1041: 1037: 1033: 1027: 1024: 1019: 1017:9780471484943 1013: 1009: 1002: 999: 988:on 2017-07-12 984: 980: 976: 969: 963: 960: 957: 952: 949: 944: 938: 934: 930: 926: 919: 917: 913: 900: 894: 891: 883: 876: 870: 867: 860: 858: 856: 852: 848: 844: 837:Related salts 836: 834: 832: 827: 825: 821: 817: 813: 809: 801: 780:OH → [(CH 762: 761: 760: 758: 754: 746: 742: 741: 740: 738: 734: 730: 725: 723: 719: 715: 707: 705: 703: 699: 695: 692: 688: 680: 677: 653: 650: 646: 622: 618: 606: 599: 594: 577: 571: 568: 567:External MSDS 565: 562: 559: 558: 551: 544: 537: 513: 510: 509: 505: 504: 501: 498: 495: 491: 490: 486: 484: 479: 476: 473: 468: 467: 463: 462: 457: 452: 448: 445: 441: 440: 436: 434: 433:Melting point 431: 430: 426: 422: 419: 418: 411: 409: 406: 405: 382: 379: 375: 374: 369: 360: 356: 349: 335: 325: 321: 314: 306: 302: 301:DTXSID4020325 298: 297: 295: 285: 281: 280: 273: 269: 268: 266: 264: 261: 260: 253: 249: 248: 246: 240: 236: 235: 232: 228: 226: 221: 220: 216: 212: 209: 207: 205:ECHA InfoCard 202: 201: 194: 190: 189: 187: 185: 182: 181: 174: 170: 169: 167: 165: 162: 161: 154: 150: 149: 147: 145: 142: 141: 134: 130: 129: 127: 123: 118: 117: 110: 106: 105: 103: 100: 96: 95: 90: 82: 79: 76: 73: 72: 67: 61: 57: 53: 47: 43: 38: 34: 29: 25: 20: 1046:19 September 1044:. Retrieved 1040:the original 1035: 1026: 1007: 1001: 990:. Retrieved 983:the original 974: 962: 951: 924: 903:. Retrieved 893: 882:the original 869: 840: 828: 805: 802:Applications 750: 726: 711: 687:bifunctional 616: 615: 507: 499: 482: 470:Main hazards 459: 173:ChEMBL282468 153:CHEBI:133341 92:Identifiers 69:Other names 59: 55: 51: 979:IPCS INCHEM 905:11 November 714:methylation 685:). It is a 494:Signal word 464:(OHS/OSH): 425:hygroscopic 420:Appearance 371:Properties 362:.OCC(C)(C)C 229:E1001(iii) 211:100.000.596 77:Hepacholine 1062:Categories 992:2009-11-10 942:3527306730 861:References 845:salts are 643:. It is a 408:Molar mass 272:45I14D8O27 184:ChemSpider 120:3D model ( 99:CAS Number 50:2-Hydroxy- 1036:FracFocus 899:"Choline" 708:Synthesis 485:labelling 475:Corrosive 427:crystals 80:Biocolina 824:glycerol 808:chickens 772:N + ClCH 698:hydroxyl 676:chloride 656:[(CH 625:[(CH 508:NFPA 704 454:Hazards 384:[(CH 224:E number 83:Lipotril 843:choline 652:cations 649:choline 598:what is 596: ( 402: 239:PubChem 109:67-48-1 1014:  939:  735:, and 696:and a 679:anions 674:) and 619:is an 593:verify 590:  563:(SDS) 500:Danger 423:White 413:139.62 355:SMILES 252:522265 164:ChEMBL 40:Names 986:(PDF) 971:(PDF) 885:(PDF) 878:(PDF) 814:with 796:OH]Cl 755:with 720:with 641:OH]Cl 400:OH]Cl 320:InChI 144:ChEBI 122:JSmol 1048:2014 1012:ISBN 937:ISBN 907:2019 849:and 816:urea 702:salt 263:UNII 193:5974 929:doi 788:NCH 764:(CH 716:of 672:OH] 664:NCH 633:NCH 483:GHS 392:NCH 289:EPA 242:CID 1064:: 1034:. 977:. 973:. 935:. 915:^ 857:. 833:. 822:, 818:, 792:CH 776:CH 759:. 731:, 724:. 683:Cl 668:CH 637:CH 487:: 396:CH 1050:. 1020:. 995:. 945:. 931:: 909:. 794:2 790:2 786:3 784:) 782:3 778:2 774:2 770:3 768:) 766:3 681:( 670:2 666:2 662:3 660:) 658:3 654:( 639:2 635:2 631:3 629:) 627:3 588:N 549:0 542:0 535:2 398:2 394:2 390:3 388:) 386:3 291:) 287:( 124:) 60:N 58:, 56:N 54:, 52:N

Index

Choline chloride

Preferred IUPAC name
CAS Number
67-48-1
JSmol
Interactive image
ChEBI
CHEBI:133341
ChEMBL
ChEMBL282468
ChemSpider
5974
ECHA InfoCard
100.000.596
Edit this at Wikidata
E number
(additional chemicals)
PubChem
522265
UNII
45I14D8O27
CompTox Dashboard
DTXSID4020325
Edit this at Wikidata
InChI
SMILES
Chemical formula
Molar mass
hygroscopic

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