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impact on cervical remodelling and thus propensity for preterm birth. Since this remodelling results in shortening of the cervix, which is thought to result in preterm birth, Hendon sought to further understand the structural properties that underlie shortening and elucidate approaches to prevent preterm birth. By assessing the collagen fiber orientation through her material modelling framework, Hendon was able to determine the basis for cervical deformation using OCT and biomechanically explore the causes of preterm birth at the level of tissue microstructure.
208:(OCT) techniques to create volumetric images of human tissues and organs for use in treatment of cardiac arrhythmias. She developed an automated algorithm for fiber orientation in the plane parallel to the wall surface of cardiac tissue in order to properly characterize early structural changes in the myocardium due to disease and injury to guide treatment. Her work showed that OCT can help to visualize real time ablation (RFA) therapy to guide physicians treatment progression and thus improve the outcomes of RFA therapy.
31:
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novel biomedical technologies for guided imaging of biological tissues and improved diagnosis and treatment of cancer and cardiac arrhythmias. Her work integrates real-time processing algorithms to extract physiological information from
Optical Coherence Tomography (OCT) imaging data. Hendon is also a member of the National Society of Black Engineers (NSBE), The International Society for Optics and Photonics (SPIE and The Optical Society (OSA).
241:
structure-function relationship of heart tissue. She showed that she was able to image, with high resolution, elastic fibers, Purkinje fibers, and collagen fiber bundles, as well as observe tissue pathology. Since the composition of atrial tissue impacts disease pathology, diagnosis, and recovery, Hendon and her team developed an automated method to classify tissue composition of the atria using a
231:
as an assistant professor in the School of
Engineering and Applied Sciences in the Department of Electrical Engineering. In 2018, Hendon was promoted to Associate Professor with tenure. Hendon is the Principal Investigator of the Structure-Function Imaging Laboratory. Her lab focuses on developing
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Hendon then became interested in exploring the structure-function relationship of the cervix and how characterizing this relationship could provide insight into causes of preterm birth and possible prevention strategies. Hendon first found that collagen fiber dispersion and directionality had an
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model. The classification accuracy was over 80% showing its utility in classifying tissue composition and guiding diagnosis and treatment. With Hendon's technology, physicians that previously treated cardiac arrhythmias essentially blind to the tissue changes, can now observe tissue changes and
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Hendon helped to improve and guide ablation treatment of atrial fibrillation using a near-infrared spectroscopy (NIRS) guided catheter implantation. Her results showed improved results of radio-frequency ablation therapy. Hendon then used her knowledge and expertise in OCT to characterize the
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Singh-Moon RP, Marboe CC, Hendon CP. Near-infrared spectroscopy integrated catheter for characterization of myocardial tissues: preliminary demonstrations to radiofrequency ablation therapy for atrial fibrillation. Biomed Opt
Express. 2015;6(7):2494-2511. Published 12 June 2015.
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Hendon began adapting her OCT algorithms for use in the diagnosis and treatment of breast cancer. The imaging technique has been nicknamed “optical ultrasound” and, using ultra-high resolution OCT, she was able to improve the characterization and diagnosis of breast cancer.
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Wang, Hui & Hendon, Christine & Rollins, Andrew. (2007). Ultrahigh-resolution optical coherence tomography at 1.15 ÎĽm using photonic crystal fiber with no zero-dispersion wavelengths. Optics
Express - OPT EXPRESS. 15.
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Ha R, Friedlander LC, Hibshoosh H, et al. Optical
Coherence Tomography: A Novel Imaging Method for Post-lumpectomy Breast Margin Assessment-A Multi-reader Study. Acad Radiol. 2018;25(3):279-287. doi:10.1016/j.acra.2017.09.018
332:
Gan Y, Yao W, Myers KM, Vink JY, Wapner RJ, Hendon CP. Analyzing three-dimensional ultrastructure of human cervical tissue using optical coherence tomography. Biomed Opt
Express. 2015;6(4):1090-1108. Published 3 March 2015.
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Hendon (born
Christine Fleming), wanted to pursue a career as a teacher during her childhood. In high school, she enjoyed math and science, and participated in the Institute for Climate and Planets program hosted by the
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Yao X, Gan Y, Chang E, Hibshoosh H, Feldman S, Hendon C. Visualization and tissue classification of human breast cancer images using ultrahigh-resolution OCT. Lasers Surg Med. 2017;49(3):258-269. doi:10.1002/lsm.22654
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Ling Y, Yao X, Hendon CP. Highly phase-stable 200 kHz swept-source optical coherence tomography based on KTN electro-optic deflector. Biomed Opt
Express. 2017;8(8):3687-3699. Published 18 July 2017.
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Yu Gan, Xinwen Yao, Chang E, et al. Comparative study of texture features in OCT images at different scales for human breast tissue classification. Conf Proc IEEE Eng Med Biol Soc. 2016;2016:3926-3929.
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Gan Y, Yao W, Myers KM, Hendon CP. An automated 3D registration method for optical coherence tomography volumes. Conf Proc IEEE Eng Med Biol Soc. 2014;2014:3873-3876. doi:10.1109/EMBC.2014.6944469
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in the
Biomedical Optics Wellman Center for Photomedicine. During this time, Hendon optimized the depth resolved spectral analysis of OCT. She completed her postdoctoral fellowship in 2012.
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Yao X, Gan Y, Marboe CC, Hendon CP. Myocardial imaging using ultrahigh-resolution spectral domain optical coherence tomography. J Biomed Opt. 2016;21(6):61006. doi:10.1117/1.JBO.21.6.061006
80:
2017 Presidential Early Career Awards for
Scientists and Engineers (PECASE), 2013 MIT Technology Review’s 35 Innovators Under 35, 2012 Forbes 30 under 30 in Science and Healthcare
662:"Near-infrared Spectroscopy Integrated Catheter for Characterization of Myocardial Tissues: Preliminary Demonstrations to Radiofrequency Ablation Therapy for Atrial Fibrillation"
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193:. She majored in Electrical Engineering and Computer Science and became immediately involved in undergraduate research. Hendon graduated with her Bachelors of Science in 2004.
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and near infrared spectroscopy systems, that enable physicians to perform guided interventional procedures and allow for structure-function dissection of
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in Biomedical Engineering. She completed her M.S. in 2007, and her Ph.D. in 2010. During her PhD, Hendon worked under the mentorship of
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is an electrical engineer and computer scientist and an associate professor in the Department of Electrical Engineering at
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Fleming, Christine P.; Eckert, Jocelyn; Halpern, Elkan F.; Gardecki, Joseph A.; Tearney, Guillermo J. (2013-08-01).
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Following her Ph.D., Hendon moved back to Massachusetts and pursued her Postdoctoral research fellowship at
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2015 Rodriguez Family Junior Faculty Development Award at the School of Engineering and Applied Science
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150:. She has been recognized for her development of optical imaging catheters for cardiac wall imaging by
861:"Visualization and Tissue Classification of Human Breast Cancer Images Using Ultrahigh-Resolution OCT"
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138:. Her advances in imaging technologies have led to improved diagnostic abilities and treatments for
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Km, Myers; Cp, Hendon; Y, Gan; W, Yao; K, Yoshida; M, Fernandez; J, Vink; Rj, Wapner (2015-06-25).
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910:"Collagen Fiber Orientation and Dispersion in the Upper Cervix of Non-Pregnant and Pregnant Women"
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126:. Hendon is a pioneer in medical imaging. She develops biomedical optics technologies, using
1100:"Professor Christine Hendon Receives 2015 Rodriguez Family Junior Faculty Development Award"
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714:"Myocardial Imaging Using Ultrahigh-Resolution Spectral Domain Optical Coherence Tomography"
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366:"Q&A: Christine Hendon wins National Science Foundation award for imaging innovations"
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774:"Automated Classification of Optical Coherence Tomography Images of Human Atrial Tissue"
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491:"Abstract 3224: Optical Coherence Tomography Imaging of Radiofrequency Ablation Lesions"
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Recipients of the Presidential Early Career Award for Scientists and Engineers
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2012 Wellman-Bullock Postdoctoral Fellowship - Massachusetts General Hospital
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X, Yao; Y, Gan; E, Chang; H, Hibshoosh; S, Feldman; C, Hendon (March 2017).
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972:"A Continuous Fiber Distribution Material Model for Human Cervical Tissue"
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W, Yao; Y, Gan; Km, Myers; Jy, Vink; Rj, Wapner; Cp, Hendon (2016-11-29).
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449:"Research and Recent Publications | Department of Biomedical Engineering"
72:
Optical coherence imaging for interventional heart arrhythmia procedures
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Characterization of Cardiac Tissue Using Optical Coherence Tomography
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improvements in realtime to enhance treatment accuracy and recovery.
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425:"Medical imaging innovator Christine Hendon wins Presidential honor"
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Hendon then pursued her Master's of Science and her PhD training at
628:"Christine P. Hendon ASSOCIATE PROFESSOR OF ELECTRICAL ENGINEERING"
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Y, Gan; D, Tsay; Sb, Amir; Cc, Marboe; Cp, Hendon (October 2016).
1045:"President Obama Honors Federally-Funded Early-Career Scientists"
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Fleming Christine P; Quan Kara J; Rollins Andrew M (2007-10-16).
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Presidential Early Career Awards for Scientists and Engineers
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In 2000, Hendon pursued her undergraduate education at the
182:. This program inspired her to pursue a career in science.
1124:"Professor Christine Hendon Wins NIH New Innovator Award"
660:
Rp, Singh-Moon; Cc, Marboe; Cp, Hendon (2015-06-12).
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International Society for Optics and Photonics (SPIE)
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X, Yao; Y, Gan; Cc, Marboe; Cp, Hendon (June 2016).
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2013 MIT Technology Review's 35 Innovators Under 35
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American electrical engineer and computer scientist
1070:"Professor Christine Hendon Wins NSF CAREER Award"
1020:"Prof. Christine Hendon Named a 2021 SPIE Fellow"
519:: CS1 maint: DOI inactive as of September 2024 (
298:2012 Forbes 30 under 30 in Science and Healthcare
1196:"Christine P. Hendon - Google Scholar Citations"
1153:Herper, Matthew; Le, Vanna; Sharf, Samantha.
286:2015 National Science Foundation Career Award
8:
158:’s 35 Innovators Under 35, and by President
478:(Thesis). Case Western Reserve University.
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1155:"30 Under 30 - Science & Healthcare"
539:Rutgers University School of Engineering
236:OCT guided atrial fibrillation treatment
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1261:21st-century American women scientists
1241:Case Western Reserve University alumni
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95:Electrical and biomedical engineering
55:Massachusetts Institute of Technology
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507:10.1161/circ.116.suppl_16.II_725-b
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227:In 2012, Hendon was recruited to
1276:21st-century American scientists
1236:MIT School of Engineering alumni
535:"Biomedical Engineering Seminar"
164:Presidential Early Career Awards
1134:from the original on 2018-06-22
1080:from the original on 2018-06-21
638:from the original on 2018-06-22
198:Case Western Reserve University
59:Case Western Reserve University
988:10.1016/j.jbiomech.2015.02.060
865:Lasers in Surgery and Medicine
472:Fleming, Christine P. (2010).
273:2021 Elected as Fellow of the
217:Massachusetts General Hospital
1:
1291:Harvard Medical School people
1256:American electrical engineers
1251:American biomedical engineers
1246:Harvard Medical School alumni
322:doi:10.1109/EMBC.2016.7591586
259:OCT imaging and preterm birth
1271:American computer scientists
935:10.1371/journal.pone.0166709
778:Journal of Biomedical Optics
718:Journal of Biomedical Optics
292:2014 NIH New Innovator Award
206:Optical Coherence Tomography
128:optical coherence tomography
1226:Columbia University faculty
1307:
798:10.1117/1.JBO.21.10.101407
738:10.1117/1.JBO.21.6.061006
666:Biomedical Optics Express
565:Biomedical Optics Express
370:www.radiologybusiness.com
109:
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1281:American women academics
632:engineering.columbia.edu
333:doi:10.1364/BOE.6.001090
329:doi:10.1364/BOE.6.002494
315:doi:10.1364/BOE.8.003687
243:relevance vector machine
191:Cambridge, Massachusetts
170:Early life and education
976:Journal of Biomechanics
509:(inactive 2024-09-19).
213:Harvard Medical School
63:Harvard Medical School
837:MIT Technology Review
401:"Christine P. Hendon"
340:10.1364/OE.15.003085.
250:OCT for breast cancer
156:MIT Technology Review
1024:Columbia Engineering
678:10.1364/BOE.6.002494
577:10.1364/BOE.4.001269
501:(suppl_16): II_725.
453:engineering.case.edu
1130:. October 6, 2014.
1104:www.ee.columbia.edu
926:2016PLoSO..1166709Y
833:"Christine Fleming"
790:2016JBO....21j1407G
730:2016JBO....21f1006Y
405:www.ee.columbia.edu
306:Select publications
229:Columbia University
223:Career and research
140:cardiac arrhythmias
120:Columbia University
116:Christine P. Hendon
104:Columbia University
23:Christine P. Hendon
1200:scholar.google.com
1076:. March 10, 2015.
877:10.1002/lsm.22654
268:Awards and honors
202:Andrew M. Rollins
154:30 under 30, the
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1203:. Retrieved
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100:Institutions
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495:Circulation
429:EurekAlert!
142:as well as
41:Nationality
1220:Categories
1205:2020-06-07
1164:2020-06-07
1109:2020-06-07
1055:2020-06-07
1030:2021-02-16
842:2020-06-07
545:2020-06-07
458:2020-06-07
434:2020-06-07
410:2020-06-07
375:2020-06-07
345:References
585:2156-7085
166:in 2017.
162:with the
1132:Archived
1078:Archived
1006:25817474
954:27898677
914:PLOS ONE
895:28264146
816:26926869
756:27001162
696:26203376
636:Archived
603:24009991
283:(PECASE)
45:American
1138:June 6,
1084:June 6,
997:6167934
945:5127549
922:Bibcode
886:5368015
807:5995000
786:Bibcode
747:4814547
726:Bibcode
687:4505704
642:June 6,
594:3756567
1159:Forbes
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