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Coccidioides immitis

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561:) have replaced it. Itraconazole (400 mg/day) appears to have efficacy equal to that of fluconazole in the treatment of nonmeningeal infection and have the same relapse rate after therapy is discontinued. However, itraconazole seems to perform better in skeletal lesions, whereas fluconazole performs better in pulmonary and soft tissue infection. Serum levels of itraconazole are commonly obtained at the onset of long-term therapy because its absorption is sometimes erratic and unpredictable. Complications can include hepatic dysfunction. For patients who are unresponsive to fluconazole, options are limited. Several case reports have studied the efficacy of three newer antifungal agents in the treatment of disease that is refractory to first-line therapy: 603:, with differing results. Caspofungin 50 mg/day following administration of amphotericin B in a patient with acute pulmonary coccidioidomycosis who had undergone transplantation showed promising results. In a patient with disseminated coccidioidomycosis, first-line therapy with amphotericin B and caspofungin alone failed to elicit a response, but the patient was then given caspofungin combined with fluconazole, with good results. A published report described a patient with disseminated and meningeal coccidioidomycosis in whom conventional therapy with fluconazole, voriconazole, and amphotericin B failed; caspofungin 50 mg/day after a loading dose of 70 mg intravenously was also unsuccessful. 279: 248: 66: 263: 44: 393:(valley fever). Its incubation period varies from 7 to 21 days. Coccidioidomycosis is not easily diagnosed on the basis of vital signs and symptoms, which are usually vague and nonspecific. Even a chest X-ray or CT scan cannot reliably distinguish it from other lung diseases, including lung cancer. Blood or urine tests are administered, which aim to discover 627:
The objectives of treatment are resolution of infection, decrease of antibody titers, return of function of involved organs, and prevention of relapse. The duration of therapy is dictated by the clinical course of the illness, but it should be at least 6 months in all patients and often a year or
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fungus can be cultured from a patient sample, but the culture can take weeks to grow and requires special precautions on a part of the laboratory staff while handling it (screw cap vials and sterile transfer hoods are recommended). It is reported as the tenth-most often acquired infection in the
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and an azole have been postulated, although no trials have been conducted. Caspofungin in combination with fluconazole has been cited as beneficial in a case report of a 31-year-old Asian patient with coccidioidal pneumonia. In a case report of a 23-year-old Black male with HIV and coccidioidal
335:, is most commonly seen in the desert regions of the southwestern United States, including certain areas of Arizona, California, New Mexico, Nevada, Texas, and Utah; and in Central and South America in Argentina, Brazil, Colombia, Guatemala, Honduras, Mexico, Nicaragua, Paraguay, and Venezuela. 628:
longer in others. Therapy is tailored based on a combination of resolution of symptoms, regression of radiographic abnormalities, and changes in CF IgG titers. Immunocompromised patients and patients with a history of meningeal involvement require lifelong treatment.
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The cost of antifungal therapy is high, from $ 5,000 to $ 20,000 per year. These costs increase for critical patients in need of intensive care. Arizona spent an average of $ 33,762 per patient with coccidioidomycosis between 1998 and 2001.
378:, sandy soils from semi-desert regions with hot summers, gentle winters, and annual rainfall between 10 and 50 centimetres (3.9 and 19.7 in). These fungi are usually found 10 to 30 centimetres (3.9 to 11.8 in) beneath the surface. 614:, introduced in 1957, remains the treatment of choice for severe infections. It is usually reserved for worsening disease or lesions located in vital organs such as the spine. It can be administered either in the classic 1161:, a presentation by Nancy L Wengenack, PhD, Director of the Mycology and Mycobacteriology Laboratories and Associate Professor of Laboratory Medicine and Pathology in the Division of Clinical Microbiology at Mayo Clinic 618:
formulation or as a lipid formulation. No studies have directly compared amphotericin B with azole therapy. Complications include renal toxicity, bone marrow toxicity, and local systemic effects (fever, rigors).
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is also being studied in salvage therapy for refractory cases. A case report indicated that voriconazole in combination with amphotericin B as salvage therapy for disseminated coccidioidomycosis was successful.
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revolutionized treatment for coccidioidomycosis, and these agents are usually the first line of therapy. However, none of these azoles are safe to use in pregnancy and lactation because they have shown
660:(42 CFR 73). However, on October 5, 2012 due to advances in medical research and development of a number of licensed treatments, both pathogens were removed from the HHS select agents listing. 549:(FDA) for treatment of coccidioidomycosis. Nevertheless, although it was initially used in the long-term treatment of nonmeningeal extrapulmonary disease, more-potent, less-toxic 573:(glucan synthesis inhibitor of the echinocandin structural class). However, these drugs have not been FDA approved, and clinical trials are lacking. Susceptibility testing of 503:
Immunosuppression (e.g., patients with HIV/AIDS, transplant recipients, patients receiving high-dose corticosteroids, those receiving antitumor necrosis factor medications)
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infections have an incubation period from one to four weeks and resolve without specific therapy; few clinical trials have assessed outcomes in less-severe disease.
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has been approved by the European Commission as a salvage therapy for refractory coccidioidomycosis. Clinical trials are now ongoing for further evaluation.
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Johnson, Royce H.; Baqi, Shehla (2008). "Chapter 16: Coccidiomycosis". In Hospenthal, Duane R.; Rinaldi, Michael G. (eds.).
950: 1685: 2233: 546: 65: 2305: 760:"Operational Guidelines (version 1.0) for Geological Fieldwork in Areas Endemic for Coccidioidomycosis (Valley Fever)" 657: 615: 736: 247: 1411: 1353: 307: 2483: 2141: 2148: 1710: 1390: 875:
Garcia Garcia SC, Salas Alanis JC, Flores MG, Gonzalez Gonzalez SE, Vera Cabrera L, Ocampo Candiani J (2015).
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species in one report revealed uniform susceptibility to most antifungal agents, including these newer drugs.
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Chronic debilitation or underlying disease, including diabetes mellitus or preexisting cardiopulmonary disease
925:"Symptoms of Valley Fever | Coccidioidomycosis | Types of Fungal Diseases | Fungal | CDC" 2534: 2229: 2192: 2134: 2059: 2034: 2028: 1825: 1517: 1439: 2342: 2257: 2188: 1927: 1916: 1845: 1835: 1820: 1726: 1691: 1663: 1628: 1600: 1418: 331: 2000: 1748: 1404: 1179: 160: 924: 1778: 2418: 2387: 2174: 2164: 1978: 1875: 1870: 1734: 1657: 676: 2519: 2286: 2014: 2006: 1840: 1432: 363: 262: 1130: 286:
with 90-degree branching and thick-walled barrel-shaped arthroconidia alternating with empty cells
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meningitis, combination therapy of amphotericin B and posaconazole led to clinical improvement.
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creates a mass that can mimic a lung tumor, the correct diagnosis may require a tissue sample (
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Code of Federal Regulations (CFR), Title 42, Part 73 (Volume 77, Number 194) - Public Health
896: 888: 847: 837: 1105: 2120: 1475: 1368: 1363: 1304: 1267: 219: 826:"The Quest for a Vaccine Against Coccidioidomycosis: A Neglected Disease of the Americas" 2413: 2248: 2065: 1922: 1772: 1761: 1740: 1634: 1299: 1217: 1199: 1024: 901: 876: 852: 825: 611: 581: 107: 1164: 2513: 2320: 2281: 2214: 2127: 2050: 1955: 1939: 1888: 1754: 1721: 1716: 1497: 1331: 1309: 1287: 649: 497:
Primary infection during pregnancy, especially in the third trimester or immediately
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is regularly found in Texas, northern Mexico and in Central and South America. Both
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Infiltrates that involve more than half of one lung or portions of both lungs
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is largely found in California, but also Baja California and Arizona, while
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Risk factors for dissemination (for which treatment should be initiated):
2465: 2359: 2292: 1855: 1235: 977:"Fungal pneumonia: a silent epidemic - Coccidioidomycosis (valley fever)" 550: 296: 2431: 1671: 1558: 1552: 1547: 1212: 1207: 1195: 842: 397: 2444: 423:
laboratory conditions with two documented deaths. Until October 2012,
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Commonly used indicators to judge the severity of illness include:
1794: 1373: 1222: 953:. Centers for Disease Control and Prevention (CDC). Archived from 538: 526: 277: 261: 246: 1159:
Identification of Coccidioides immitis and Coccidioides posadasii
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Anticoccidioidal complement fixation IgG titers of 1:16 or higher
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Frederick S. Fisher; Mark W. Bultman; Demosthenes Pappagianis.
1073:"Treatment and Outcomes for Coccidioidomycosis (Valley Fever)" 274:. This is the infective form of the fungus occurring in nature 569:(triazole compounds similar in structure to fluconazole) and 1102:
Code of Federal Regulations (CFR), Title 42 - Public Health
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Absence of dermal hypersensitivity to coccidioidal antigens
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organism's characteristic spherules within the tissue. The
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on Sabouraud's medium, showing white, cottony fungus growth
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U.S. Geological Survey Open-File Report 00-348 Version 1.0
877:"Coccidioidomycosis and the skin: a comprehensive review" 512:
Certain ethnicities, such as Filipino, Black, or Hispanic
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Intense night sweats that persist for more than 3 weeks
803:. Totowa, New Jersey: Humana Press. pp. 295–315. 2349: 2274: 2247: 2213: 2158: 2104: 2089: 2049: 1938: 1793: 1702: 1586: 1575: 1566: 1546: 1496: 1453: 1382: 1276: 1261: 1252: 1206: 1075:. Centers for Disease Control and Prevention (CDC) 1053:. Centers for Disease Control and Prevention (CDC) 1005:. Centers for Disease Control and Prevention (CDC) 982:. Centers for Disease Control and Prevention (CDC) 1104:. Office of the Federal Register. Archived from 1051:"Symptoms of Coccidioidomycosis (Valley Fever)" 580:In very severe cases, combination therapy with 1180: 8: 654:U.S. Department of Health and Human Services 486:Symptoms that persist for more than 2 months 433:U.S. Department of Health and Human Services 266:Microscopic appearance of an old culture of 238:(G.W.Stiles) Bogliolo & J.A.Neves (1952) 2337: 2101: 1583: 1572: 1563: 1273: 1258: 1249: 1187: 1173: 1165: 42: 31: 1412:Trichophyton interdigitale/mentagrophytes 900: 851: 841: 801:Diagnosis and Treatment of Human Mycoses 474:Prominent or persistent hilar adenopathy 462:Continuous fever for longer than 1 month 210:(G.W.Stiles) Verdun & Mandoul (1924) 1966:Allergic bronchopulmonary aspergillosis 1650:Progressive disseminated histoplasmosis 1003:"Infectious Diseases Related To Travel" 717:. Public Health Agency of Canada (PHAC) 668: 701: 699: 697: 683:. Species Fungorum. CAB International 545:is the only one approved by the U.S. 414:can then confirm the presence of the 7: 1881:Erosio interdigitalis blastomycetica 1621:Primary pulmonary coccidioidomycosis 1617:Primary cutaneous coccidioidomycosis 951:"Coccidioidomycosis (Valley Fever)" 1001:Loretta S. Chang; Tom M. Chiller. 599:Several case reports have studied 25: 465:Body-weight loss of more than 10% 1866:Congenital cutaneous candidiasis 1645:Primary pulmonary histoplasmosis 1640:Primary cutaneous histoplasmosis 1347:Proximal subungual onychomycosis 1137:. Office of the Federal Register 652:and toxins list compiled by the 494:Primary infection during infancy 64: 1971:Primary cutaneous aspergillosis 1612:Disseminated coccidioidomycosis 1337:White superficial onychomycosis 771:U.S. Department of the Interior 412:Gomori methenamine silver stain 314:, and a few other areas in the 1342:Distal subungual onychomycosis 1131:"HHS select agents and toxins" 1095:"HHS select agents and toxins" 1029:Tom Volk's Fungus of the Month 437:U.S. Department of Agriculture 230:(G.W.Stiles) A.Agostini (1932) 1: 1686:Paracoccidioides brasiliensis 893:10.1590/abd1806-4841.20153805 737:"Coccidioides group database" 623:Duration of therapy and costs 2234:Encephalitozoon intestinalis 1727:South American blastomycosis 1722:North American blastomycosis 1327:Tinea pedis (athlete's foot) 547:Food and Drug Administration 370:is more common east of it. 2306:Granuloma gluteale infantum 1332:Tinea unguium/onychomycosis 707:"Infectious Disease Index: 658:Code of Federal Regulations 656:(HHS), as evident from the 616:amphotericin B deoxycholate 389:can cause a disease called 362:is more common west of the 2551: 2530:Fungal pathogens of humans 1354:Tinea corporis gladiatorum 824:Kirkland, Theo N. (2016). 329:, along with its relative 308:southwestern United States 2142:Syncephalastrum racemosum 636:HHS select agents listing 358:are present in Arizona. 191: 184: 166: 159: 61:Scientific classification 59: 50: 41: 34: 2149:Apophysomyces variabilis 1711:Blastomyces dermatitidis 1426:Trichophyton schoenleini 1391:Epidermophyton floccosum 306:in certain parts of the 2525:Fungi described in 1896 2230:Enterocytozoon bieneusi 2193:Conidiobolus incongruus 2135:Lichtheimia corymbifera 2060:Cryptococcus neoformans 2029:Pseudallescheria boydii 1518:Malassezia folliculitis 1440:Trichophyton verrucosum 677:"GSD Species Synonymy: 509:High inoculum exposures 439:, and was considered a 400:. However, because the 2258:Rhinosporidium seeberi 2189:Conidiobolus coronatus 1928:Pneumocystis pneumonia 1917:Pneumocystis jirovecii 1846:Candidal onychomycosis 1836:Antibiotic candidiasis 1692:Paracoccidioidomycosis 1664:African histoplasmosis 1629:Histoplasma capsulatum 1601:Coccidioides posadasii 1419:Trichophyton tonsurans 1025:"Coccidioides immitis" 382:Clinical manifestation 287: 275: 259: 215:Blastomycoides immitis 55:growing in petri dish 2001:Phialophora verrucosa 1831:Chronic mucocutaneous 1749:Talaromyces marneffei 1405:Microsporum audouinii 427:had been listed as a 281: 270:, showing fragmented 265: 250: 2351:Coccidioides immitis 2175:Basidiobolus ranarum 2165:Entomophthoramycosis 1979:Exophiala jeanselmei 1876:Systemic candidiasis 1871:Perianal candidiasis 1735:Sporothrix schenckii 1658:Histoplasma duboisii 1597:Coccidioides immitis 709:Coccidioides immitis 679:Coccidioides immitis 648:was featured on the 525:The introduction of 302:that resides in the 292:Coccidioides immitis 284:Coccidioides immitis 268:Coccidioides immitis 256:Coccidioides immitis 170:Coccidioides immitis 53:Coccidioides immitis 36:Coccidioides immitis 2287:Fungal folliculitis 2015:Geotrichum candidum 2007:Chromoblastomycosis 1851:Candidal paronychia 1841:Candidal intertrigo 1433:Trichophyton rubrum 534:in animal studies. 364:Tehachapi Mountains 18:Coccidiodes immitis 2199:Conidiobolomycosis 2181:Basidiobolomycosis 1997:Fonsecaea compacta 1993:Fonsecaea pedrosoi 1861:Diaper candidiasis 1607:Coccidioidomycosis 1111:on 20 October 2013 1031:. Tom Volk's Fungi 843:10.3390/jof2040034 391:coccidioidomycosis 374:spp. are found in 316:Western Hemisphere 288: 282:Septate hyphae of 276: 260: 2507: 2506: 2492:Open Tree of Life 2343:Taxon identifiers 2334: 2333: 2326:Phaeohyphomycosis 2311:Hyalohyphomycosis 2243: 2242: 2209: 2208: 2045: 2044: 1789: 1788: 1542: 1541: 1507:Malassezia furfur 1492: 1491: 1462:Hortaea werneckii 1449: 1448: 1398:Microsporum canis 931:. 13 January 2021 810:978-1-59745-325-7 739:. Broad Institute 483:Inability to work 441:biosafety level 3 245: 244: 239: 231: 227:Geotrichum immite 223: 211: 203: 27:Species of fungus 16:(Redirected from 2542: 2500: 2499: 2487: 2486: 2474: 2473: 2461: 2460: 2448: 2447: 2435: 2434: 2422: 2421: 2409: 2408: 2396: 2395: 2383: 2382: 2370: 2369: 2368: 2338: 2264:Rhinosporidiosis 2220:Microsporidiosis 2160:Entomophthorales 2102: 2079:Trichosporonosis 1805:Candida albicans 1779:Adiaspiromycosis 1584: 1573: 1564: 1513:Tinea versicolor 1274: 1259: 1250: 1196:Fungal infection 1189: 1182: 1175: 1166: 1147: 1146: 1144: 1142: 1127: 1121: 1120: 1118: 1116: 1110: 1099: 1091: 1085: 1084: 1082: 1080: 1069: 1063: 1062: 1060: 1058: 1047: 1041: 1040: 1038: 1036: 1021: 1015: 1014: 1012: 1010: 998: 992: 991: 989: 987: 981: 973: 967: 966: 964: 962: 947: 941: 940: 938: 936: 921: 915: 914: 904: 881:An Bras Dermatol 872: 866: 865: 855: 845: 830:Journal of Fungi 821: 815: 814: 796: 790: 789: 787: 785: 779: 773:. Archived from 764: 755: 749: 748: 746: 744: 733: 727: 726: 724: 722: 703: 692: 691: 689: 688: 673: 339:Precise location 237: 235:Aleurisma immite 229: 217: 209: 207:Mycoderma immite 197: 195:Zymonema immitis 172: 69: 68: 46: 32: 21: 2550: 2549: 2545: 2544: 2543: 2541: 2540: 2539: 2510: 2509: 2508: 2503: 2495: 2490: 2482: 2477: 2469: 2464: 2456: 2451: 2443: 2438: 2430: 2425: 2417: 2412: 2404: 2399: 2391: 2386: 2378: 2373: 2364: 2363: 2358: 2345: 2335: 2330: 2270: 2239: 2217: 2205: 2162: 2154: 2121:Rhizopus oryzae 2108: 2093: 2085: 2041: 1934: 1785: 1698: 1579: 1556: 1551: 1538: 1488: 1476:Piedraia hortae 1445: 1378: 1369:Tinea incognito 1364:Tinea imbricata 1268:Dermatophytosis 1265: 1239: 1230: 1221: 1215: 1211: 1202: 1193: 1155: 1150: 1140: 1138: 1129: 1128: 1124: 1114: 1112: 1108: 1097: 1093: 1092: 1088: 1078: 1076: 1071: 1070: 1066: 1056: 1054: 1049: 1048: 1044: 1034: 1032: 1023: 1022: 1018: 1008: 1006: 1000: 999: 995: 985: 983: 979: 975: 974: 970: 960: 958: 949: 948: 944: 934: 932: 923: 922: 918: 874: 873: 869: 823: 822: 818: 811: 798: 797: 793: 783: 781: 780:on 4 March 2013 777: 762: 757: 756: 752: 742: 740: 735: 734: 730: 720: 718: 705: 704: 695: 686: 684: 675: 674: 670: 666: 638: 625: 609: 523: 449: 384: 341: 324: 180: 174: 168: 155: 152:C. immitis 63: 28: 23: 22: 15: 12: 11: 5: 2548: 2546: 2538: 2537: 2535:Fungus species 2532: 2527: 2522: 2512: 2511: 2505: 2504: 2502: 2501: 2488: 2475: 2462: 2449: 2436: 2423: 2410: 2397: 2384: 2371: 2355: 2353: 2347: 2346: 2341: 2332: 2331: 2329: 2328: 2323: 2318: 2313: 2308: 2303: 2302: 2301: 2289: 2284: 2278: 2276: 2272: 2271: 2269: 2268: 2267: 2266: 2253: 2251: 2249:Mesomycetozoea 2245: 2244: 2241: 2240: 2238: 2237: 2225: 2223: 2211: 2210: 2207: 2206: 2204: 2203: 2202: 2201: 2185: 2184: 2183: 2170: 2168: 2156: 2155: 2153: 2152: 2145: 2138: 2131: 2124: 2116: 2114: 2099: 2087: 2086: 2084: 2083: 2082: 2081: 2076: 2068: 2066:Cryptococcosis 2055: 2053: 2047: 2046: 2043: 2042: 2040: 2039: 2038: 2037: 2035:Allescheriasis 2025: 2024: 2023: 2011: 2010: 2009: 1989: 1988: 1987: 1975: 1974: 1973: 1968: 1963: 1958: 1945: 1943: 1936: 1935: 1933: 1932: 1931: 1930: 1925: 1923:Pneumocystosis 1913: 1906: 1899: 1892: 1885: 1884: 1883: 1878: 1873: 1868: 1863: 1858: 1853: 1848: 1843: 1838: 1833: 1828: 1823: 1818: 1813: 1800: 1798: 1791: 1790: 1787: 1786: 1784: 1783: 1782: 1781: 1773:Emmonsia parva 1769: 1764: 1762:Scedosporiosis 1759: 1758: 1757: 1745: 1744: 1743: 1741:Sporotrichosis 1731: 1730: 1729: 1724: 1719: 1706: 1704: 1700: 1699: 1697: 1696: 1695: 1694: 1682: 1681: 1680: 1668: 1667: 1666: 1654: 1653: 1652: 1647: 1642: 1637: 1635:Histoplasmosis 1625: 1624: 1623: 1614: 1609: 1592: 1590: 1581: 1570: 1561: 1544: 1543: 1540: 1539: 1537: 1536: 1535: 1534: 1522: 1521: 1520: 1515: 1502: 1500: 1494: 1493: 1490: 1489: 1487: 1486: 1485: 1484: 1472: 1471: 1470: 1457: 1455: 1451: 1450: 1447: 1446: 1444: 1443: 1436: 1429: 1422: 1415: 1408: 1401: 1394: 1386: 1384: 1380: 1379: 1377: 1376: 1371: 1366: 1361: 1356: 1351: 1350: 1349: 1344: 1339: 1329: 1324: 1319: 1314: 1313: 1312: 1310:Dermatophytids 1307: 1300:Tinea corporis 1297: 1296: 1295: 1280: 1278: 1271: 1256: 1247: 1218:dermatomycosis 1204: 1203: 1200:mesomycetozoea 1194: 1192: 1191: 1184: 1177: 1169: 1163: 1162: 1154: 1153:External links 1151: 1149: 1148: 1122: 1086: 1064: 1042: 1016: 993: 968: 957:on 9 July 2013 942: 916: 867: 864:. Art. No. 34. 816: 809: 791: 750: 728: 693: 667: 665: 662: 637: 634: 624: 621: 612:Amphotericin B 608: 605: 582:amphotericin B 532:teratogenicity 522: 519: 518: 517: 516: 515: 513: 510: 507: 504: 501: 495: 489: 488: 487: 484: 481: 478: 475: 472: 469: 466: 463: 457: 448: 445: 383: 380: 340: 337: 323: 320: 272:chlamydospores 243: 242: 241: 240: 232: 224: 212: 204: 189: 188: 182: 181: 175: 164: 163: 157: 156: 149: 147: 143: 142: 135: 131: 130: 125: 121: 120: 115: 111: 110: 108:Eurotiomycetes 105: 101: 100: 95: 91: 90: 85: 81: 80: 75: 71: 70: 57: 56: 48: 47: 39: 38: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 2547: 2536: 2533: 2531: 2528: 2526: 2523: 2521: 2518: 2517: 2515: 2498: 2493: 2489: 2485: 2480: 2476: 2472: 2467: 2463: 2459: 2454: 2450: 2446: 2441: 2437: 2433: 2428: 2424: 2420: 2415: 2411: 2407: 2402: 2398: 2394: 2389: 2385: 2381: 2376: 2372: 2367: 2361: 2357: 2356: 2354: 2352: 2348: 2344: 2339: 2327: 2324: 2322: 2321:Keratomycosis 2319: 2317: 2314: 2312: 2309: 2307: 2304: 2300: 2297: 2296: 2295: 2294: 2290: 2288: 2285: 2283: 2282:Alternariosis 2280: 2279: 2277: 2273: 2265: 2262: 2261: 2260: 2259: 2255: 2254: 2252: 2250: 2246: 2236: 2235: 2231: 2227: 2226: 2224: 2221: 2216: 2215:Microsporidia 2212: 2200: 2197: 2196: 2195: 2194: 2190: 2186: 2182: 2179: 2178: 2177: 2176: 2172: 2171: 2169: 2166: 2161: 2157: 2151: 2150: 2146: 2144: 2143: 2139: 2137: 2136: 2132: 2130: 2129: 2128:Mucor indicus 2125: 2123: 2122: 2118: 2117: 2115: 2112: 2107: 2103: 2100: 2097: 2092: 2088: 2080: 2077: 2074: 2073: 2069: 2067: 2064: 2063: 2062: 2061: 2057: 2056: 2054: 2052: 2051:Basidiomycota 2048: 2036: 2033: 2032: 2031: 2030: 2026: 2022: 2019: 2018: 2017: 2016: 2012: 2008: 2005: 2004: 2003: 2002: 1998: 1994: 1990: 1986: 1983: 1982: 1981: 1980: 1976: 1972: 1969: 1967: 1964: 1962: 1959: 1957: 1956:Aspergillosis 1954: 1953: 1952: 1951: 1947: 1946: 1944: 1941: 1937: 1929: 1926: 1924: 1921: 1920: 1919: 1918: 1914: 1912: 1911: 1910:C. tropicalis 1907: 1905: 1904: 1903:C. lusitaniae 1900: 1898: 1897: 1893: 1891: 1890: 1886: 1882: 1879: 1877: 1874: 1872: 1869: 1867: 1864: 1862: 1859: 1857: 1854: 1852: 1849: 1847: 1844: 1842: 1839: 1837: 1834: 1832: 1829: 1827: 1824: 1822: 1819: 1817: 1814: 1812: 1809: 1808: 1807: 1806: 1802: 1801: 1799: 1796: 1792: 1780: 1777: 1776: 1775: 1774: 1770: 1768: 1765: 1763: 1760: 1756: 1755:Talaromycosis 1753: 1752: 1751: 1750: 1746: 1742: 1739: 1738: 1737: 1736: 1732: 1728: 1725: 1723: 1720: 1718: 1717:Blastomycosis 1715: 1714: 1713: 1712: 1708: 1707: 1705: 1701: 1693: 1690: 1689: 1688: 1687: 1683: 1679: 1676: 1675: 1674: 1673: 1672:Lacazia loboi 1669: 1665: 1662: 1661: 1660: 1659: 1655: 1651: 1648: 1646: 1643: 1641: 1638: 1636: 1633: 1632: 1631: 1630: 1626: 1622: 1618: 1615: 1613: 1610: 1608: 1605: 1604: 1603: 1602: 1598: 1594: 1593: 1591: 1589: 1585: 1582: 1578: 1574: 1571: 1569: 1565: 1562: 1560: 1559:opportunistic 1554: 1549: 1545: 1533: 1530: 1529: 1528: 1527: 1523: 1519: 1516: 1514: 1511: 1510: 1509: 1508: 1504: 1503: 1501: 1499: 1498:Basidiomycota 1495: 1483: 1480: 1479: 1478: 1477: 1473: 1469: 1466: 1465: 1464: 1463: 1459: 1458: 1456: 1452: 1442: 1441: 1437: 1435: 1434: 1430: 1428: 1427: 1423: 1421: 1420: 1416: 1414: 1413: 1409: 1407: 1406: 1402: 1400: 1399: 1395: 1393: 1392: 1388: 1387: 1385: 1381: 1375: 1372: 1370: 1367: 1365: 1362: 1360: 1357: 1355: 1352: 1348: 1345: 1343: 1340: 1338: 1335: 1334: 1333: 1330: 1328: 1325: 1323: 1320: 1318: 1315: 1311: 1308: 1306: 1303: 1302: 1301: 1298: 1294: 1291: 1290: 1289: 1288:tinea capitis 1285: 1282: 1281: 1279: 1275: 1272: 1269: 1264: 1260: 1257: 1255: 1251: 1248: 1246: 1242: 1237: 1233: 1228: 1224: 1219: 1214: 1209: 1205: 1201: 1197: 1190: 1185: 1183: 1178: 1176: 1171: 1170: 1167: 1160: 1157: 1156: 1152: 1136: 1132: 1126: 1123: 1107: 1103: 1096: 1090: 1087: 1074: 1068: 1065: 1052: 1046: 1043: 1030: 1026: 1020: 1017: 1004: 997: 994: 978: 972: 969: 956: 952: 946: 943: 930: 926: 920: 917: 912: 908: 903: 898: 894: 890: 886: 882: 878: 871: 868: 863: 859: 854: 849: 844: 839: 835: 831: 827: 820: 817: 812: 806: 802: 795: 792: 776: 772: 768: 761: 754: 751: 738: 732: 729: 716: 712: 710: 702: 700: 698: 694: 682: 680: 672: 669: 663: 661: 659: 655: 651: 650:select agents 647: 643: 635: 633: 629: 622: 620: 617: 613: 606: 604: 602: 597: 594: 590: 586: 583: 578: 576: 575:Coccidioides 572: 568: 564: 560: 556: 552: 548: 544: 540: 535: 533: 528: 520: 514: 511: 508: 505: 502: 500: 496: 493: 492: 490: 485: 482: 479: 476: 473: 470: 467: 464: 461: 460: 458: 455: 451: 450: 446: 444: 442: 438: 434: 430: 426: 421: 417: 413: 409: 405: 404: 399: 396: 392: 388: 381: 379: 377: 373: 369: 365: 361: 357: 353: 349: 345: 338: 336: 334: 333: 328: 321: 319: 317: 313: 309: 305: 301: 298: 294: 293: 285: 280: 273: 269: 264: 257: 253: 249: 236: 233: 228: 225: 221: 218:(G.W.Stiles) 216: 213: 208: 205: 201: 198:(G.W.Stiles) 196: 193: 192: 190: 187: 183: 178: 173: 171: 165: 162: 161:Binomial name 158: 154: 153: 148: 145: 144: 141: 140: 136: 133: 132: 129: 126: 123: 122: 119: 116: 113: 112: 109: 106: 103: 102: 99: 96: 93: 92: 89: 86: 83: 82: 79: 76: 73: 72: 67: 62: 58: 54: 49: 45: 40: 37: 33: 30: 19: 2350: 2291: 2256: 2228: 2187: 2173: 2147: 2140: 2133: 2126: 2119: 2111:Mucormycosis 2072:Trichosporon 2070: 2058: 2027: 2021:Geotrichosis 2013: 1991: 1977: 1961:Aspergilloma 1948: 1915: 1908: 1901: 1894: 1887: 1826:Vulvovaginal 1803: 1771: 1747: 1733: 1709: 1684: 1670: 1656: 1627: 1596: 1595: 1580:(yeast+mold) 1548:Subcutaneous 1532:White piedra 1526:Trichosporon 1524: 1505: 1482:Black piedra 1474: 1460: 1438: 1431: 1424: 1417: 1410: 1403: 1396: 1389: 1359:Tinea faciei 1322:Tinea manuum 1317:Tinea cruris 1284:Tinea barbae 1263:Dermatophyte 1139:. Retrieved 1134: 1125: 1113:. Retrieved 1106:the original 1101: 1089: 1077:. Retrieved 1067: 1055:. Retrieved 1045: 1033:. Retrieved 1028: 1019: 1007:. Retrieved 996: 984:. Retrieved 971: 959:. Retrieved 955:the original 945: 933:. Retrieved 928: 919: 887:(5): 610–9. 884: 880: 870: 833: 829: 819: 800: 794: 782:. Retrieved 775:the original 766: 753: 741:. Retrieved 731: 719:. Retrieved 714: 708: 685:. Retrieved 681:G.W. Stiles" 678: 671: 645: 642:C. posadasii 641: 639: 630: 626: 610: 607:Amphotericin 598: 593:Voriconazole 589:Posaconazole 587: 579: 574: 567:voriconazole 563:posaconazole 559:itraconazole 543:ketoconazole 536: 524: 498: 454:Coccidioides 453: 431:by both the 429:select agent 424: 419: 416:Coccidioides 415: 403:Coccidioides 401: 395:Coccidioides 394: 386: 385: 372:Coccidioides 371: 368:C. posadasii 367: 359: 356:C. posadasii 355: 351: 348:C. posadasii 347: 343: 342: 332:C. posadasii 330: 326: 325: 322:Epidemiology 291: 290: 289: 283: 267: 255: 234: 226: 214: 206: 194: 169: 167: 151: 150: 139:Coccidioides 138: 52: 51:colonies of 35: 29: 2440:iNaturalist 2096:Zygomycosis 1950:Aspergillus 1896:C. glabrata 1811:Candidiasis 1767:Emmonsiosis 1678:Lobomycosis 1468:Tinea nigra 1383:By organism 1277:By location 1208:Superficial 935:20 December 715:MDSC Online 640:Along with 601:caspofungin 571:caspofungin 555:fluconazole 499:post partum 310:, northern 254:culture of 128:Onygenaceae 2520:Onygenales 2514:Categories 2316:Otomycosis 2299:Fusariosis 2091:Zygomycota 1985:Eumycetoma 1821:Esophageal 1588:Onygenales 1568:Ascomycota 1254:Ascomycota 687:2016-02-06 664:References 646:C. immitis 443:pathogen. 425:C. immitis 420:C. immitis 387:C. immitis 360:C. immitis 352:C. immitis 344:C. immitis 327:C. immitis 297:pathogenic 177:G.W.Stiles 118:Onygenales 98:Ascomycota 94:Division: 2275:Ungrouped 2106:Mucorales 1577:Dimorphic 1241:endothrix 1213:cutaneous 551:triazoles 447:Treatment 146:Species: 84:Kingdom: 78:Eukaryota 2466:MycoBank 2458:11329401 2414:Fungorum 2366:Q5139154 2360:Wikidata 2293:Fusarium 1889:C. auris 1856:Candidid 1553:systemic 1305:Ringworm 1236:exothrix 911:26560205 862:29376949 435:and the 398:antigens 376:alkaline 366:, while 220:Castell. 186:Synonyms 124:Family: 74:Domain: 2432:4911585 1141:11 July 1115:11 July 1079:11 July 1057:11 July 1035:11 July 1009:12 July 986:11 July 961:11 July 929:Cdc.gov 902:4631225 853:5715932 784:12 July 743:11 July 721:16 July 537:Of the 134:Genus: 114:Order: 104:Class: 2497:838981 2471:416228 2445:350381 2419:416228 2406:CCDIIM 2393:244854 1293:Kerion 1232:Piedra 909:  899:  860:  850:  807:  539:azoles 527:azoles 521:Azoles 408:biopsy 312:Mexico 300:fungus 252:Sputum 222:(1928) 202:(1918) 179:(1896) 2453:IRMNG 2380:5ZGBZ 1942:-like 1797:-like 1795:Yeast 1703:Other 1454:Other 1374:Favus 1223:Tinea 1109:(PDF) 1098:(PDF) 980:(PDF) 836:(4). 778:(PDF) 763:(PDF) 452:Most 410:). A 295:is a 200:Mello 88:Fungi 2484:5501 2479:NCBI 2427:GBIF 2401:EPPO 1940:Mold 1816:Oral 1557:and 1245:hair 1243:) = 1227:skin 1198:and 1143:2013 1117:2013 1081:2013 1059:2013 1037:2013 1011:2013 988:2013 963:2013 937:2021 907:PMID 858:PMID 805:ISBN 786:2013 745:2013 723:2013 565:and 557:and 354:and 304:soil 2388:EoL 2375:CoL 2075:spp 1210:and 897:PMC 889:doi 848:PMC 838:doi 2516:: 2494:: 2481:: 2468:: 2455:: 2442:: 2429:: 2416:: 2403:: 2390:: 2377:: 2362:: 1619:. 1225:= 1220:): 1133:. 1100:. 1027:. 927:. 905:. 895:. 885:90 883:. 879:. 856:. 846:. 832:. 828:. 769:. 765:. 713:. 696:^ 644:, 541:, 318:. 2232:/ 2222:) 2218:( 2191:/ 2167:) 2163:( 2113:) 2109:( 2098:) 2094:( 1999:/ 1995:/ 1599:/ 1555:, 1550:, 1286:/ 1270:) 1266:( 1238:/ 1234:( 1229:; 1216:( 1188:e 1181:t 1174:v 1145:. 1119:. 1083:. 1061:. 1039:. 1013:. 990:. 965:. 939:. 913:. 891:: 840:: 834:2 813:. 788:. 747:. 725:. 711:" 690:. 553:( 20:)

Index

Coccidiodes immitis

Scientific classification
Edit this classification
Eukaryota
Fungi
Ascomycota
Eurotiomycetes
Onygenales
Onygenaceae
Coccidioides
Binomial name
G.W.Stiles
Synonyms
Mello
Castell.

Sputum

chlamydospores

pathogenic
fungus
soil
southwestern United States
Mexico
Western Hemisphere
C. posadasii
Tehachapi Mountains
alkaline

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