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Crystal C. Watkins Johansson

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prevention programs. In the laboratory and the clinic, Johansson has explored the severity and prevalence of the neuropsychiatric complications of HIV infection that remain regardless of antiretroviral therapy due to the harboring of virus in microglia and astrocytes in the brain. Based on the infection of glial cells in patients with HIV, Johansson has also conducted studies exploring the extent of neuroinflammation in patients with HIV using Positron Emission Tomography with the PET ligand TSPO. The positive signal associated with the TSPO ligand is thought to be correlated with increased glial cell activation. She found that there were white matter abnormalities in patients with HIV on combination antiretroviral therapies compared to controls and white matter abnormalities increased in patients that also had HIV associated dementia.
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dysfunction in patients with diabetes. She found that in mouse models of diabetes, there is a significant reduction in neuronal nitric oxide synthase mRNA and that insulin treatment restores the nNOS levels. Further, the delay in gastric emptying can be reversed with the phosphodiesterase inhibitor, sildenafil. Her PhD work led to a patent for a drug to treat neuropathic pain in patients with diabetes and the work was covered in the Wall Street Journal. Johansson completed her MD/PhD in 2003, becoming the first female Meyerhoff Scholar to obtain an MD/PhD. Johansson was also one of only three Black women at the time to graduate with a doctorate in molecular and cellular neuroscience from Johns Hopkins University School of Medicine.
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the clinical side, Johansson volunteers with the Adolescent Depression Awareness Program which educated high school students, teachers, and parents about adolescent depression. She has been featured on several news broadcasting networks such as WBALTV, The Maryland Daily Record, The Baltimore Sun, WYPR, Science Magazine, and ConscienHealth.
126:. During her MD/PhD she developed a novel treatment for gastrointestinal in patients with diabetes that led to a patent for a pharmacological compound in 2000. Johansson is a practicing neuropsychiatrist with a focus on geriatric psychiatry and she conducts brain imaging research as well as research on cancer in African American women. 322: 218:
research. She has found that African American women with breast cancer and undergoing chemotherapy treatment benefit from comprehensive psychological care programs in terms of coping capacity and distress associated with disease. She has also explored how chemotherapy affects daily life in African American women.
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Johansson has been committed to educating communities and patients about HIV/AIDs prevention as well as conducting research on the psychological and neurological complications of the various stages of infection. She worked with the Ministry of Health in Ghana to implement HIV/AID health education and
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Johansson continued her medical training at JHU, pursuing her residency training in psychiatry. She completed her Internship at Sinai Hospital at Johns Hopkins in 2004, and then went on to complete her residency training in Psychiatry and Behavioral Sciences in 2008. During her residency, she became
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Johansson is actively involved in advocacy, mentorship, and education. She co-founded a literacy program for youth and teaches adolescents about preventing teen pregnancy. She is also on the ABRCMS Steering Committee which hosts the largest professional conference for underrepresented students. On
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As a neuropsychiatrist, Johansson treats memory loss and provides geriatric psychiatry services. She also explores how psychiatric or psychological dysfunction relates to cancer and systemic disease progression and recovery, with a focus on African American women, who are understudied in clinical
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In 2011, Johansson became an assistant professor of psychiatry at Johns Hopkins University. In 2014, she became the Director of the Sheppard Pratt Memory Clinic in Neuropsychiatry and has since been promoted to associate professor at JHU. As a clinician and a professor, Johansson treats patients,
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Fellow, an Academic Medicine Fellow of the National Medical Fellowships and Bristol-Myers Squibb Inc. Her thesis was titled "Nitric Oxide and Carbon Monoxide: Novel Neurotransmitters in the Enteric Nervous System". For her graduate work, she explored the mechanisms underlying gastrointestinal
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Johansson P, Jones DE, Watkins CC, Haisfield-Wolfe ME, Gaston-Johansson F. Physicians' and nurses' experiences of the influence of race and ethnicity on the quality of healthcare provided to minority patients, and on their own professional careers. J Natl Black Nurses Assoc.
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which is a competitive program that funds the undergraduate degrees of underrepresented minorities at UMBC. She majored in biological sciences and was interested in diabetes research since her grandmother had diabetes. Johansson graduated in 1995 with a Bachelors of Science.
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Watkins CC, Boehning D, Kaplin AI, Rao M, Ferris CD, Snyder SH. Carbon monoxide mediates vasoactive intestinal polypeptide-associated nonadrenergic/noncholinergic neurotransmission. Proc Natl Acad Sci U S A. 2004;101(8):2631‐2635.
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ligand, TSPO, to visualize neuroinflammation in the human brain. She then completed a fellowship in Mood Disorders and Neuroimaging at Johns Hopkins in 2009. She then completed another Fellowship in Geriatric Psychiatry in 2011.
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Watkins CC, Sawa A, Pomper MG. Glia and immune cell signaling in bipolar disorder: insights from neuropharmacology and molecular imaging to clinical application. Transl Psychiatry. 2014;4(1):e350. Published 2014 Jan 21.
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Watkins CC, Kamara Kanu I, Hamilton JB, Kozachik SL, Gaston-Johansson F. Differences in Coping Among African American Women With Breast Cancer and Triple-Negative Breast Cancer. Oncol Nurs Forum. 2017;44(6):689‐702.
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Rahn KA, Watkins CC, Alt J, et al. Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis. Proc Natl Acad Sci U S A. 2012;109(49):20101‐20106.
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Pieper AA, Brat DJ, Krug DK, et al. Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proc Natl Acad Sci U S A. 1999;96(6):3059‐3064. doi:10.1073/pnas.96.6.3059
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Watkins CC, Sawa A, Jaffrey S, et al. Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy . J Clin Invest. 2000;106(3):373‐384. doi:10.1172/JCI8273
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Watkins CC, Pieper AA, Treisman GJ. Safety considerations in drug treatment of depression in HIV-positive patients: an updated review. Drug Saf. 2011;34(8):623‐639. doi:10.2165/11592070-000000000-00000
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Endres, Christopher J.; Pomper, Martin G.; James, Michelle; Uzuner, Ovsev; Hammoud, Dima A.; Watkins, Crystal C.; Reynolds, Aaron; Hilton, John; Dannals, Robert F.; Kassiou, Michael (August 2009).
317:, Watkins, Crystal C.; Snyder, Solomon H. & Ferris, Christopher D., "Methods for prevention and treatment of gastrointestinal disorders", published 2004-08-10, assigned to 1008:
Coughlin, Jennifer M.; Wang, Yuchuan; Ma, Shuangchao; Yue, Chen; Kim, Pearl K.; Adams, Ashley V.; Roosa, Heidi V.; Gage, Kenneth L.; Stathis, Marigo; Rais, Rana; Rojas, Camilo (June 2014).
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Gaton-Johansson, Fannie; Watkins, Crystal C.; Kanu, Iye Kamara; Whitehouse, Erin; Sarenmalm, Elisabeth Kenne; Brovall, Maria; Kozachik, Sharon L. (December 2015).
767: 138:. She wanted to become a doctor from a young age. She attended public school in Baltimore City and became the first Black president of the student government at 289:
Watkins CC, Andrews SR. Clinical studies of neuroinflammatory mechanisms in schizophrenia. Schizophr Res. 2016;176(1):14‐22. doi:10.1016/j.schres.2015.07.018
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Meyerhoff Scholar, Top 100 Women in Maryland, Physician of the Year by the Daily Record, UMBC Outstanding Alumnus in Natural & Mathematical Sciences
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Watkins CC, Treisman GJ. Neuropsychiatric complications of aging with HIV. J Neurovirol. 2012;18(4):277‐290. doi:10.1007/s13365-012-0108-z
146:. During high school, she completed an internship through the Nursing Program at Johns Hopkins to begin to explore the field of medicine. 1372: 1397: 1362: 162: 111: 1367: 1073: 1327: 1097:
Watkins, Crystal C.; Kamara Kanu, Iye; Hamilton, Jill B.; Kozachik, Sharon L.; Gaston-Johansson, Fannie (November 1, 2017).
465: 154: 119: 183: 1010:"Regional brain distribution of translocator protein using [(11)C]DPA-713 PET in individuals infected with HIV" 165:. During her PhD training, she worked in the Department of Molecular and Cellular Neuroscience under the mentorship of 1235: 790: 759: 441: 1284: 376: 566:
Watkins, C. C.; Sawa, A.; Jaffrey, S.; Blackshaw, S.; Barrow, R. K.; Snyder, S. H.; Ferris, C. D. (August 2000).
791:"'Agents of change:' A year with the UMBC program shaping some of the nation's best and most diverse scientists" 442:"'Agents of change:' A year with the UMBC program shaping some of the nation's best and most diverse scientists" 892: 318: 170: 54: 568:"Insulin restores neuronal nitric oxide synthase expression and function that is lost in diabetic gastropathy" 1146:"The Effects of Symptoms on Quality of Life during Chemotherapy in African-American Women with Breast Cancer" 347: 1392: 143: 1099:"Differences in Coping Among African American Women With Breast Cancer and Triple-Negative Breast Cancer" 921:"2009 Outstanding Alumni of the Year Awards - College of Engineering and Information Technology - UMBC" 815: 314: 179: 139: 178:
the Chief Resident of Psychiatry and also completed her postdoctoral work under the mentorship of
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is an American neuroscientist and psychiatrist and associate professor of neuroscience at
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After completing her undergraduate degree, Johansson pursued her MD/PhD training at
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as well as the director of the Sheppard Pratt Memory Clinic in Neuropsychiatry in
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conducts clinical research, and educates the future generation of physicians.
1161: 1122: 1033: 971: 727: 593: 625: 508: 135: 115: 1179: 1130: 1114: 1051: 989: 745: 611: 962: 704:"Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans" 946:"Cognitive impairment in patients with AIDS - prevalence and severity" 466:"To Whom Much Is Given The Meyerhoff Alumni Advisory Board Newsletter" 64:
Role of nitric oxide synthase in diabetic gastrointestinal dysfunction
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2009 UMBC Outstanding Alumnus in Natural & Mathematical Sciences
153:(UMBC) for her undergraduate education. She was supported by the 679:"Dr. Crystal Watkins, MD, Psychiatry Specialist - Baltimore, MD" 509:"Outstanding Recent Graduate Award 2013 | Johns Hopkins Alumni" 1236:"BREAKING NEWS: The Daily Record Announces 2012 Top 100 Women" 650:"Environmental Factor: September 2008: The Meyerhoff Model" 1195:"Expression /Regulation of Neuronal Nos in Enteric NS and" 169:, whom she met as an undergraduate at UMBC. She became a 213:
Psychological coping strategies and disease progression
893:"Setting Aside Important Medical Care for Urgent Care" 1279: 1277: 816:"UMBC STEM Scholar Success Heads to the West Coast" 251:
2019 name Physician of the Year by the Daily Record
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(2015). 230:1999 Predoctoral National Research Service Award 1378:University of Maryland, Baltimore County alumni 248:2019 name Health Care Hero by the Daily Record 1150:Journal of National Black Nurses' Association 626:"History - Meyerhoff Scholars Program - UMBC" 8: 838:: CS1 maint: multiple names: authors list ( 309: 307: 245:2016 Levi Watkins Inaugural Keynote Lecturer 877:: CS1 maint: numeric names: authors list ( 378:Dr. Crystal Watkins-Johansson on psychiatry 233:2004 Outstanding Intern of the Year JHUSOM 163:Johns Hopkins University School of Medicine 112:Johns Hopkins University School of Medicine 96:Johns Hopkins University School of Medicine 236:2006 Visionary Leadership Award from UMBC 18: 1169: 1041: 979: 961: 735: 601: 583: 1285:"Crystal Watkins Johansson, M.D., Ph.D." 348:"Crystal Watkins Johansson, M.D., Ph.D." 151:University of Maryland, Baltimore County 124:University of Maryland, Baltimore County 51:University of Maryland, Baltimore County 1383:Johns Hopkins School of Medicine alumni 303: 118:. Johansson was the first Black female 1322: 1320: 1318: 1316: 1314: 1312: 1310: 1308: 1306: 1304: 1206: 1204: 1092: 1090: 950:HIV/AIDS: Research and Palliative Care 870: 831: 1003: 1001: 999: 915: 913: 853:MervisJul. 24, Jeffrey (2019-07-24). 673: 671: 669: 572:The Journal of Clinical Investigation 204:HIV/AIDs medical service and research 7: 561: 559: 557: 532: 530: 528: 503: 501: 499: 497: 435: 433: 431: 398: 396: 394: 371: 369: 367: 342: 340: 338: 336: 334: 332: 242:2012 named Top 100 Women in Maryland 14: 134:Johansson was born and raised in 1388:Johns Hopkins University faculty 1216:News and Stories for UMBC Alumni 789:Rentz, Catherine (18 May 2018). 440:Rentz, Catherine (18 May 2018). 149:In 1991, Johansson attended the 814:Harvie, Sheilah Kast, Maureen. 770:from the original on 2020-06-13 482:from the original on 2020-06-13 416:from the original on 2020-06-13 1358:American women neuroscientists 1: 1328:"Watkins CC - Search Results" 760:"ABRCMS Stands in Solidarity" 155:Meyerhoff Scholarship Program 122:to obtain an MD/PhD from the 184:Positron Emission Tomography 108:Crystal C. Watkins Johansson 23:Crystal C. Watkins Johansson 1403:21st-century American women 708:Journal of Nuclear Medicine 282:doi:10.1073/pnas.1209934109 268:doi:10.1073/pnas.0308695100 227:1992-1995 Meyerhoff Scholar 1419: 1066:"Crystal Watkins, MD, PhD" 293:doi:10.1188/17.ONF.689-702 1373:Scientists from Baltimore 1026:10.1007/s13365-014-0239-5 720:10.2967/jnumed.109.062265 404:"Health Care Heroes 2019" 101: 76: 1398:American women academics 1363:American neuroscientists 1014:Journal of Neurovirology 319:Johns Hopkins University 171:Society for Neuroscience 130:Early life and education 55:Johns Hopkins University 1262:www.hopkinsmedicine.org 286:doi:10.1038/tp.2013.119 16:American neuroscientist 1368:American psychiatrists 1115:10.1188/17.ONF.689-702 1103:Oncology Nursing Forum 351:Maryland Daily Record 654:factor.niehs.nih.gov 542:neuroscience.jhu.edu 256:Select publications 191:Career and research 140:Dulaney High School 136:Baltimore, Maryland 116:Baltimore, Maryland 33:Baltimore, Maryland 1193:Watkins, Crystal. 963:10.2147/HIV.S39665 630:meyerhoff.umbc.edu 538:"Alumni Directory" 513:www.alumni.jhu.edu 473:meyerhoff.umbc.edu 1256:McQuay, Jessica. 1212:"Crystal Watkins" 272:2011;22(1):43‐56. 222:Awards and honors 167:Solomon H. Snyder 120:Meyerhoff Scholar 105: 104: 78:Scientific career 1410: 1342: 1341: 1339: 1338: 1324: 1299: 1298: 1296: 1295: 1281: 1272: 1271: 1269: 1268: 1253: 1247: 1246: 1244: 1243: 1232: 1226: 1225: 1223: 1222: 1208: 1199: 1198: 1190: 1184: 1183: 1173: 1141: 1135: 1134: 1094: 1085: 1084: 1082: 1081: 1072:. Archived from 1062: 1056: 1055: 1045: 1005: 994: 993: 983: 965: 941: 935: 934: 932: 931: 917: 908: 907: 905: 904: 889: 883: 882: 876: 868: 866: 865: 850: 844: 843: 837: 829: 827: 826: 811: 805: 804: 802: 801: 795:baltimoresun.com 786: 780: 779: 777: 775: 766:. 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Index

University of Maryland, Baltimore County
Johns Hopkins University
Johns Hopkins University School of Medicine
Johns Hopkins University School of Medicine
Baltimore, Maryland
Meyerhoff Scholar
University of Maryland, Baltimore County
Baltimore, Maryland
Dulaney High School
Cockeysville
University of Maryland, Baltimore County
Meyerhoff Scholarship Program
Johns Hopkins University School of Medicine
Solomon H. Snyder
Society for Neuroscience
Martin G. Pomper
Positron Emission Tomography


US 6774128
Johns Hopkins University






"Crystal Watkins Johansson, M.D., Ph.D."

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