170:
195:
2463:
417:
410:
403:
201:
31:
1184:
protein family of adhesion junction plaque proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of some variants has not been defined. It has been known that some isoforms are expressed in neural and muscle
2170:
Nomura K, Sugawara T, Sato T, Sawamura D, Hashimoto I, Sugita Y, Uitto J (1995). "Expression of laminin, type IV procollagen and 230 kDa bullous pemphigoid antigen genes by keratinocytes and fibroblasts in culture: application of the polymerase chain reaction for detection of small amounts of
57:
2040:
Owaribe K, Kartenbeck J, Stumpp S, Magin TM, Krieg T, Diaz LA, Franke WW (December 1990). "The hemidesmosomal plaque. I. Characterization of a major constituent protein as a differentiation marker for certain forms of epithelia".
2105:
Mutasim DF, Morrison LH, Takahashi Y, Labib RS, Skouge J, Diaz LA, Anhalt GJ (February 1989). "Definition of bullous pemphigoid antibody binding to intracellular and extracellular antigen associated with hemidesmosomes".
1596:"The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expression"
1365:
Sawamura D, Nomura K, Sugita Y, Mattei MG, Chu ML, Knowlton R, Uitto J (December 1990). "Bullous pemphigoid antigen (BPAG1): cDNA cloning and mapping of the gene to the short arm of human chromosome 6".
1463:"The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome"
2462:
1418:
Koster J, Geerts D, Favre B, Borradori L, Sonnenberg A (January 2003). "Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly".
2011:
Sawamura D, Li KH, Nomura K, Sugita Y, Christiano AM, Uitto J (June 1991). "Bullous pemphigoid antigen: cDNA cloning, cellular expression, and evidence for polymorphism of the human gene".
2387:"Structural analysis of the predicted coiled-coil rod domain of the cytoplasmic bullous pemphigoid antigen (BPAG1). Empirical localization of the N-terminal globular domain-rod boundary"
1635:
Pool M, Boudreau Larivière C, Bernier G, Young KG, Kothary R (December 2005). "Genetic alterations at the Bpag1 locus in dt mice and their impact on transcript expression".
208:
2315:"The human 230-kD bullous pemphigoid antigen gene (BPAG1). Exon-intron organization and identification of regulatory tissue specific elements in the promoter region"
1943:"Comparison of molecularly cloned bullous pemphigoid antigen to desmoplakin I confirms that they define a new family of cell adhesion junction plaque proteins"
1978:"Human bullous pemphigoid antigen (BPAG1). Amino acid sequences deduced from cloned cDNAs predict biologically important peptide segments and protein domains"
1240:
mutant mouse lines have been described which share the common feature of having sensory neuron degeneration. In humans, loss of dystonin function can cause
1241:
131:
806:
1248:. In both human diseases, pathology is likely attributable to the loss of the dystonin-a2 protein isoform, which plays a role in neuronal autophagy.
2208:
Brown A, Lemieux N, Rossant J, Kothary R (July 1994). "Human homolog of a mouse sequence from the dystonia musculorum locus is on chromosome 6p12".
2442:
2284:
Elgart GW, Stanley JR (August 1993). "Cloning of the 5' mRNA for the 230-kD bullous pemphigoid antigen by rapid amplification of cDNA ends".
2496:
2491:
1298:
1559:
Bhanot K, Young KG, Kothary R (November 2011). "MAP1B and clathrin are novel interacting partners of the giant cyto-linker dystonin".
1099:
2356:
Brown A, Dalpé G, Mathieu M, Kothary R (October 1995). "Cloning and characterization of the neural isoforms of human dystonin".
2137:"A pool of bullous pemphigoid antigen(s) is intracellular and associated with the basal cell cytoskeleton-hemidesmosome complex"
1404:
1285:
194:
169:
1281:
1213:
119:
1245:
1209:
207:
2435:
2471:: Crystal Structure of a protease resistant fragment of the plakin domain of Bullous Pemphigoid Antigen1 (BPAG1)
200:
54:
849:
1200:. Consistent with the expression, mice defective for this gene show skin blistering and neurodegeneration.
1193:
1908:"Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones"
2428:
183:
106:
2072:"Bullous pemphigoid antigen localization suggests an intracellular association with hemidesmosomes"
1854:"Disruption in the autophagic process underlies the sensory neuropathy in dystonia musculorum mice"
1063:
1059:
1055:
1051:
1047:
1025:
1021:
982:
978:
974:
970:
966:
962:
936:
932:
928:
1318:"Isolation of complementary DNA for bullous pemphigoid antigen by use of patients' autoantibodies"
110:, BPA, BPAG1, CATX-15, CATX15, D6S1101, DMH, DT, EBSB2, HSAN6, MACF2, dystonin, BP230, BP240, EBS3
2233:
2196:
1660:
1443:
1257:
143:
1037:
1033:
1029:
958:
954:
944:
940:
2247:"Identification of a second protein product of the gene encoding a human epidermal autoantigen"
1852:
Ferrier A, De
Repentigny Y, Lynch-Godrei A, Gibeault S, Eid W, Kuo D, Zha X, Kothary R (2015).
2408:
2373:
2344:
2301:
2272:
2225:
2188:
2158:
2123:
2093:
2058:
2028:
1999:
1964:
1929:
1883:
1834:
1785:
1736:
1701:
1652:
1617:
1576:
1541:
1492:
1435:
1383:
1347:
99:
47:
2501:
2398:
2365:
2334:
2326:
2293:
2262:
2254:
2217:
2180:
2148:
2115:
2083:
2050:
2020:
1989:
1954:
1919:
1873:
1865:
1824:
1816:
1775:
1767:
1728:
1691:
1644:
1607:
1568:
1531:
1523:
1482:
1474:
1427:
1375:
1337:
1329:
287:
218:
1594:
Favre B, Fontao L, Koster J, Shafaatian R, Jaunin F, Saurat JH, et al. (August 2001).
416:
409:
402:
1225:
262:
139:
2267:
2246:
2054:
1878:
1853:
1829:
1804:
1780:
1755:
1536:
1511:
1510:
Liu JJ, Ding J, Kowal AS, Nardine T, Allen E, Delcroix JD, et al. (October 2003).
2339:
2314:
1994:
1977:
1959:
1942:
1342:
1317:
740:
735:
730:
725:
720:
715:
710:
705:
700:
695:
690:
685:
669:
664:
659:
654:
649:
644:
639:
634:
629:
624:
619:
614:
609:
604:
599:
594:
589:
584:
579:
574:
569:
564:
559:
554:
549:
544:
539:
534:
529:
524:
508:
503:
498:
493:
488:
483:
478:
473:
468:
463:
458:
2485:
1487:
1462:
1379:
1197:
1192:, and some isoforms are expressed in epithelial tissue, anchoring keratin-containing
445:
2200:
1664:
1447:
30:
1719:
Lalonde R, Strazielle C (September–December 2023). "The DST gene in neurobiology".
1189:
280:
160:
2237:
1869:
1805:"Isoform-specific loss of dystonin causes hereditary motor and sensory neuropathy"
1732:
2297:
2153:
2136:
2119:
2088:
2071:
2024:
1820:
1771:
147:
2135:
Mutasim DF, Takahashi Y, Labib RS, Anhalt GJ, Patel HP, Diaz LA (January 1985).
1303:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1648:
177:
127:
2403:
2386:
1924:
1907:
1906:
Nakajima D, Okazaki N, Yamakawa H, Kikuno R, Ohara O, Nagase T (June 2002).
770:
380:
301:
246:
233:
135:
2369:
1933:
1887:
1838:
1789:
1740:
1705:
1656:
1621:
1612:
1595:
1580:
1545:
1496:
1439:
2412:
2377:
2348:
2305:
2276:
2229:
2192:
2162:
2127:
2097:
2062:
2032:
2003:
1968:
1527:
1387:
1351:
1142:
1941:
Tanaka T, Parry DA, Klaus-Kovtun V, Steinert PM, Stanley JR (July 1991).
1512:"BPAG1n4 is essential for retrograde axonal transport in sensory neurons"
1478:
1316:
Stanley JR, Tanaka T, Mueller S, Klaus-Kovtun V, Roop D (December 1988).
1131:
892:
2221:
2184:
1167:
878:
835:
2330:
2258:
1572:
1431:
1333:
76:
1696:
1679:
1181:
1112:
792:
1756:"HSAN-VI: A spectrum disorder based on dystonin isoform expression"
2313:
Tamai K, Sawamura D, Do HC, Tamai Y, Li K, Uitto J (August 1993).
1221:
1217:
1186:
755:
751:
1174:
123:
2424:
2420:
425:
270:
1185:
tissue, anchoring neural intermediate filaments to the
392:
1976:
Sawamura D, Li K, Chu ML, Uitto J (September 1991).
1077:
1020:
996:
927:
2070:Westgate GE, Weaver AC, Couchman JR (March 1985).
1277:
1275:
1273:
2043:Differentiation; Research in Biological Diversity
1803:Motley WW, Züchner S, Scherer SS (October 2020).
217:
2385:Tang HY, Chaffotte AF, Thacher SM (April 1996).
706:intermediate filament cytoskeleton organization
2436:
8:
1754:Lynch-Godrei A, Kothary R (February 2020).
1282:GRCh38: Ensembl release 89: ENSG00000151914
1242:hereditary sensory and autonomic neuropathy
2443:
2429:
2421:
1017:
924:
766:
441:
258:
155:
65:
2402:
2338:
2266:
2152:
2087:
1993:
1958:
1923:
1877:
1828:
1779:
1695:
1611:
1535:
1486:
1341:
2286:The Journal of Investigative Dermatology
2141:The Journal of Investigative Dermatology
2108:The Journal of Investigative Dermatology
2076:The Journal of Investigative Dermatology
2013:The Journal of Investigative Dermatology
1399:
1397:
1232:Loss of function in neurological disease
18:Neurologically significant human protein
2458:
1461:Hopkinson SB, Jones JC (January 2000).
1269:
20:
2319:The Journal of Clinical Investigation
1678:Young KG, Kothary R (December 2007).
1322:The Journal of Clinical Investigation
721:microtubule cytoskeleton organization
222:
181:
176:
7:
2245:Hopkinson SB, Jones JC (June 1994).
1164:bullous pemphigoid antigen 1 (BPAG1)
736:cytoplasmic microtubule organization
2391:The Journal of Biological Chemistry
2173:Archives of Dermatological Research
1982:The Journal of Biological Chemistry
1947:The Journal of Biological Chemistry
1600:The Journal of Biological Chemistry
711:integrin-mediated signaling pathway
2055:10.1111/j.1432-0436.1990.tb00475.x
1684:Cell Motility and the Cytoskeleton
1180:This gene encodes a member of the
1074:
993:
902:
883:
859:
840:
816:
797:
630:intermediate filament cytoskeleton
397:
358:
296:
275:
14:
1680:"Dystonin/Bpag1--a link to what?"
1170:that in humans is encoded by the
464:protein homodimerization activity
2461:
415:
408:
401:
344:inferior ganglion of vagus nerve
206:
199:
193:
168:
29:
545:endoplasmic reticulum membrane
530:integral component of membrane
426:More reference expression data
381:More reference expression data
1:
1995:10.1016/S0021-9258(18)55195-4
1960:10.1016/S0021-9258(18)98934-9
1870:10.1080/15548627.2015.1052207
1733:10.1080/01677063.2024.2319880
1467:Molecular Biology of the Cell
1166:, isoforms 1/2/3/4/5/8, is a
191:
2298:10.1111/1523-1747.ep12365083
2154:10.1111/1523-1747.ep12274684
2120:10.1111/1523-1747.ep12276753
2089:10.1111/1523-1747.ep12265229
2025:10.1111/1523-1747.ep12475433
1821:10.1212/NXG.0000000000000496
1772:10.1212/NXG.0000000000000389
1561:Journal of Proteome Research
1380:10.1016/0888-7543(90)90261-R
1214:collagen, type XVII, alpha 1
716:maintenance of cell polarity
509:cytoskeletal protein binding
504:structural molecule activity
469:microtubule plus-end binding
2497:EF-hand-containing proteins
2492:Genes on human chromosome 6
1516:The Journal of Cell Biology
1405:"Entrez Gene: DST dystonin"
1246:Charcot-Marie-Tooth disease
1208:Dystonin has been shown to
726:retrograde axonal transport
2518:
2253:. 300 ( Pt 3) (3): 851–7.
484:protein C-terminus binding
2456:
1649:10.1007/s00335-005-0073-4
1299:"Human PubMed Reference:"
1146:
1141:
1137:
1130:
1111:
1094:
1081:
1044:
1013:
1000:
951:
920:
909:
905:
890:
886:
877:
866:
862:
847:
843:
834:
823:
819:
804:
800:
791:
776:
769:
765:
749:
731:cytoskeleton organization
444:
440:
423:
400:
391:
378:
365:
361:
308:
299:
269:
261:
257:
240:
227:
190:
167:
158:
154:
117:
114:
104:
97:
92:
73:
68:
51:
46:
41:
37:
28:
23:
1721:Journal of Neurogenetics
560:microtubule cytoskeleton
336:external globus pallidus
328:inferior olivary nucleus
320:internal globus pallidus
2404:10.1074/jbc.271.16.9716
2251:The Biochemical Journal
1420:Journal of Cell Science
1100:Chr 6: 56.46 – 56.95 Mb
2370:10.1006/geno.1995.9936
1613:10.1074/jbc.M011005200
1194:intermediate filaments
686:hemidesmosome assembly
52:Human UniProt search:
1925:10.1093/dnares/9.3.99
1528:10.1083/jcb.200306075
640:intermediate filament
635:extracellular exosome
620:endoplasmic reticulum
600:basal plasma membrane
1479:10.1091/mbc.11.1.277
701:response to wounding
580:microtubule plus-end
184:Chromosome 6 (human)
69:List of PDB id codes
42:Available structures
1809:Neurology. Genetics
1760:Neurology. Genetics
1244:type VI and axonal
665:cytoplasmic vesicle
499:microtubule binding
459:calcium ion binding
340:subthalamic nucleus
2222:10.1007/BF00357004
2185:10.1007/BF00371801
1258:Bullous pemphigoid
679:Biological process
625:actin cytoskeleton
518:Cellular component
452:Molecular function
2479:
2478:
2331:10.1172/JCI116655
2259:10.1042/bj3000851
1573:10.1021/pr200564g
1432:10.1242/jcs.00241
1334:10.1172/JCI113803
1154:
1153:
1150:
1149:
1126:
1125:
1090:
1089:
1071:
1070:
1009:
1008:
990:
989:
916:
915:
899:
898:
873:
872:
856:
855:
830:
829:
813:
812:
761:
760:
615:cell leading edge
585:basement membrane
474:metal ion binding
436:
435:
432:
431:
387:
386:
374:
373:
355:
354:
253:
252:
88:
87:
84:
83:
2509:
2465:
2445:
2438:
2431:
2422:
2416:
2406:
2381:
2352:
2342:
2309:
2280:
2270:
2241:
2210:Mammalian Genome
2204:
2171:messenger RNA".
2166:
2156:
2131:
2101:
2091:
2066:
2036:
2007:
1997:
1988:(27): 17784–90.
1972:
1962:
1937:
1927:
1892:
1891:
1881:
1849:
1843:
1842:
1832:
1800:
1794:
1793:
1783:
1751:
1745:
1744:
1716:
1710:
1709:
1699:
1697:10.1002/cm.20235
1675:
1669:
1668:
1637:Mammalian Genome
1632:
1626:
1625:
1615:
1606:(35): 32427–36.
1591:
1585:
1584:
1556:
1550:
1549:
1539:
1507:
1501:
1500:
1490:
1458:
1452:
1451:
1426:(Pt 2): 387–99.
1415:
1409:
1408:
1401:
1392:
1391:
1362:
1356:
1355:
1345:
1313:
1307:
1306:
1295:
1289:
1279:
1162:, also known as
1139:
1138:
1122:
1107:
1102:
1085:
1075:
1066:
1018:
1014:RefSeq (protein)
1004:
994:
985:
925:
903:
884:
860:
841:
817:
798:
767:
540:nuclear envelope
479:integrin binding
442:
428:
419:
412:
405:
398:
383:
359:
304:
302:Top expressed in
297:
276:
259:
249:
236:
225:
210:
203:
197:
186:
172:
156:
150:
109:
102:
79:
66:
60:
39:
38:
33:
21:
2517:
2516:
2512:
2511:
2510:
2508:
2507:
2506:
2482:
2481:
2480:
2475:
2472:
2466:
2452:
2449:
2419:
2397:(16): 9716–22.
2384:
2355:
2312:
2283:
2244:
2207:
2169:
2134:
2104:
2069:
2039:
2010:
1975:
1953:(19): 12555–9.
1940:
1905:
1901:
1899:Further reading
1896:
1895:
1851:
1850:
1846:
1802:
1801:
1797:
1753:
1752:
1748:
1718:
1717:
1713:
1690:(12): 897–905.
1677:
1676:
1672:
1634:
1633:
1629:
1593:
1592:
1588:
1567:(11): 5118–27.
1558:
1557:
1553:
1509:
1508:
1504:
1460:
1459:
1455:
1417:
1416:
1412:
1403:
1402:
1395:
1364:
1363:
1359:
1315:
1314:
1310:
1297:
1296:
1292:
1280:
1271:
1266:
1254:
1234:
1206:
1143:View/Edit Human
1120:
1105:
1098:
1095:Location (UCSC)
1083:
1062:
1058:
1054:
1050:
1046:
1040:
1036:
1032:
1028:
1024:
1002:
981:
977:
973:
969:
965:
961:
957:
953:
947:
943:
939:
935:
931:
850:ENSG00000151914
745:
674:
570:plasma membrane
535:cell projection
513:
489:protein binding
424:
414:
413:
407:
406:
379:
370:
351:
346:
342:
338:
334:
330:
326:
324:pars reticulata
322:
318:
316:Achilles tendon
314:
312:corpus callosum
300:
244:
231:
223:
213:
212:
211:
204:
182:
159:Gene location (
148:DST - orthologs
118:
105:
98:
75:
53:
19:
12:
11:
5:
2515:
2513:
2505:
2504:
2499:
2494:
2484:
2483:
2477:
2476:
2474:
2473:
2467:
2460:
2457:
2454:
2453:
2450:
2448:
2447:
2440:
2433:
2425:
2418:
2417:
2382:
2353:
2310:
2281:
2242:
2205:
2167:
2132:
2102:
2067:
2037:
2008:
1973:
1938:
1902:
1900:
1897:
1894:
1893:
1864:(7): 1025–36.
1844:
1795:
1746:
1711:
1670:
1643:(12): 909–17.
1627:
1586:
1551:
1502:
1453:
1410:
1393:
1357:
1328:(6): 1864–70.
1308:
1290:
1268:
1267:
1265:
1262:
1261:
1260:
1253:
1250:
1233:
1230:
1205:
1202:
1198:hemidesmosomes
1152:
1151:
1148:
1147:
1145:
1135:
1134:
1128:
1127:
1124:
1123:
1118:
1116:
1109:
1108:
1103:
1096:
1092:
1091:
1088:
1087:
1079:
1078:
1072:
1069:
1068:
1042:
1041:
1015:
1011:
1010:
1007:
1006:
998:
997:
991:
988:
987:
949:
948:
922:
918:
917:
914:
913:
907:
906:
900:
897:
896:
888:
887:
881:
875:
874:
871:
870:
864:
863:
857:
854:
853:
845:
844:
838:
832:
831:
828:
827:
821:
820:
814:
811:
810:
802:
801:
795:
789:
788:
783:
778:
774:
773:
763:
762:
759:
758:
747:
746:
744:
743:
738:
733:
728:
723:
718:
713:
708:
703:
698:
693:
688:
682:
680:
676:
675:
673:
672:
670:axon cytoplasm
667:
662:
657:
652:
647:
642:
637:
632:
627:
622:
617:
612:
607:
602:
597:
592:
587:
582:
577:
572:
567:
562:
557:
555:focal adhesion
552:
547:
542:
537:
532:
527:
521:
519:
515:
514:
512:
511:
506:
501:
496:
491:
486:
481:
476:
471:
466:
461:
455:
453:
449:
448:
438:
437:
434:
433:
430:
429:
421:
420:
395:
389:
388:
385:
384:
376:
375:
372:
371:
369:
366:
363:
362:
356:
353:
352:
350:
349:
348:body of uterus
345:
341:
337:
333:
329:
325:
321:
317:
313:
309:
306:
305:
293:
292:
284:
273:
267:
266:
263:RNA expression
255:
254:
251:
250:
242:
238:
237:
229:
226:
221:
215:
214:
205:
198:
192:
188:
187:
180:
174:
173:
165:
164:
152:
151:
116:
112:
111:
103:
95:
94:
90:
89:
86:
85:
82:
81:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
2514:
2503:
2500:
2498:
2495:
2493:
2490:
2489:
2487:
2470:
2464:
2459:
2455:
2446:
2441:
2439:
2434:
2432:
2427:
2426:
2423:
2414:
2410:
2405:
2400:
2396:
2392:
2388:
2383:
2379:
2375:
2371:
2367:
2364:(3): 777–80.
2363:
2359:
2354:
2350:
2346:
2341:
2336:
2332:
2328:
2325:(2): 814–22.
2324:
2320:
2316:
2311:
2307:
2303:
2299:
2295:
2291:
2287:
2282:
2278:
2274:
2269:
2264:
2260:
2256:
2252:
2248:
2243:
2239:
2235:
2231:
2227:
2223:
2219:
2215:
2211:
2206:
2202:
2198:
2194:
2190:
2186:
2182:
2179:(7): 408–13.
2178:
2174:
2168:
2164:
2160:
2155:
2150:
2146:
2142:
2138:
2133:
2129:
2125:
2121:
2117:
2114:(2): 225–30.
2113:
2109:
2103:
2099:
2095:
2090:
2085:
2082:(3): 218–24.
2081:
2077:
2073:
2068:
2064:
2060:
2056:
2052:
2049:(3): 207–20.
2048:
2044:
2038:
2034:
2030:
2026:
2022:
2019:(6): 908–15.
2018:
2014:
2009:
2005:
2001:
1996:
1991:
1987:
1983:
1979:
1974:
1970:
1966:
1961:
1956:
1952:
1948:
1944:
1939:
1935:
1931:
1926:
1921:
1918:(3): 99–106.
1917:
1913:
1909:
1904:
1903:
1898:
1889:
1885:
1880:
1875:
1871:
1867:
1863:
1859:
1855:
1848:
1845:
1840:
1836:
1831:
1826:
1822:
1818:
1814:
1810:
1806:
1799:
1796:
1791:
1787:
1782:
1777:
1773:
1769:
1765:
1761:
1757:
1750:
1747:
1742:
1738:
1734:
1730:
1726:
1722:
1715:
1712:
1707:
1703:
1698:
1693:
1689:
1685:
1681:
1674:
1671:
1666:
1662:
1658:
1654:
1650:
1646:
1642:
1638:
1631:
1628:
1623:
1619:
1614:
1609:
1605:
1601:
1597:
1590:
1587:
1582:
1578:
1574:
1570:
1566:
1562:
1555:
1552:
1547:
1543:
1538:
1533:
1529:
1525:
1521:
1517:
1513:
1506:
1503:
1498:
1494:
1489:
1484:
1480:
1476:
1473:(1): 277–86.
1472:
1468:
1464:
1457:
1454:
1449:
1445:
1441:
1437:
1433:
1429:
1425:
1421:
1414:
1411:
1406:
1400:
1398:
1394:
1389:
1385:
1381:
1377:
1373:
1369:
1361:
1358:
1353:
1349:
1344:
1339:
1335:
1331:
1327:
1323:
1319:
1312:
1309:
1304:
1300:
1294:
1291:
1287:
1283:
1278:
1276:
1274:
1270:
1263:
1259:
1256:
1255:
1251:
1249:
1247:
1243:
1239:
1231:
1229:
1227:
1223:
1219:
1215:
1211:
1203:
1201:
1199:
1195:
1191:
1188:
1183:
1178:
1176:
1173:
1169:
1165:
1161:
1158:
1144:
1140:
1136:
1133:
1129:
1119:
1117:
1114:
1110:
1104:
1101:
1097:
1093:
1086:
1080:
1076:
1073:
1067:
1065:
1061:
1057:
1053:
1049:
1043:
1039:
1035:
1031:
1027:
1023:
1019:
1016:
1012:
1005:
999:
995:
992:
986:
984:
980:
976:
972:
968:
964:
960:
956:
950:
946:
942:
938:
934:
930:
926:
923:
921:RefSeq (mRNA)
919:
912:
908:
904:
901:
895:
894:
889:
885:
882:
880:
876:
869:
865:
861:
858:
852:
851:
846:
842:
839:
837:
833:
826:
822:
818:
815:
809:
808:
803:
799:
796:
794:
790:
787:
784:
782:
779:
775:
772:
768:
764:
757:
753:
748:
742:
741:wound healing
739:
737:
734:
732:
729:
727:
724:
722:
719:
717:
714:
712:
709:
707:
704:
702:
699:
697:
696:cell adhesion
694:
692:
691:cell motility
689:
687:
684:
683:
681:
678:
677:
671:
668:
666:
663:
661:
658:
656:
653:
651:
648:
646:
643:
641:
638:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
601:
598:
596:
595:cell junction
593:
591:
588:
586:
583:
581:
578:
576:
575:hemidesmosome
573:
571:
568:
566:
563:
561:
558:
556:
553:
551:
548:
546:
543:
541:
538:
536:
533:
531:
528:
526:
523:
522:
520:
517:
516:
510:
507:
505:
502:
500:
497:
495:
494:actin binding
492:
490:
487:
485:
482:
480:
477:
475:
472:
470:
467:
465:
462:
460:
457:
456:
454:
451:
450:
447:
446:Gene ontology
443:
439:
427:
422:
418:
411:
404:
399:
396:
394:
390:
382:
377:
367:
364:
360:
357:
347:
343:
339:
335:
332:Pars compacta
331:
327:
323:
319:
315:
311:
310:
307:
303:
298:
295:
294:
291:
289:
285:
283:
282:
278:
277:
274:
272:
268:
264:
260:
256:
248:
243:
239:
235:
230:
220:
216:
209:
202:
196:
189:
185:
179:
175:
171:
166:
162:
157:
153:
149:
145:
141:
137:
133:
129:
125:
121:
113:
108:
101:
96:
91:
80:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
16:
2468:
2394:
2390:
2361:
2357:
2322:
2318:
2292:(2): 244–6.
2289:
2285:
2250:
2216:(7): 434–7.
2213:
2209:
2176:
2172:
2147:(1): 47–53.
2144:
2140:
2111:
2107:
2079:
2075:
2046:
2042:
2016:
2012:
1985:
1981:
1950:
1946:
1915:
1912:DNA Research
1911:
1861:
1857:
1847:
1812:
1808:
1798:
1763:
1759:
1749:
1727:(4): 131–8.
1724:
1720:
1714:
1687:
1683:
1673:
1640:
1636:
1630:
1603:
1599:
1589:
1564:
1560:
1554:
1522:(2): 223–9.
1519:
1515:
1505:
1470:
1466:
1456:
1423:
1419:
1413:
1374:(4): 722–6.
1371:
1367:
1360:
1325:
1321:
1311:
1302:
1293:
1237:
1235:
1207:
1204:Interactions
1190:cytoskeleton
1179:
1171:
1163:
1159:
1156:
1155:
1082:
1064:NP_001361665
1060:NP_001361663
1056:NP_001361659
1052:NP_001361658
1048:NP_001361651
1045:
1026:NP_001138242
1022:NP_001138241
1001:
983:NM_001386100
979:NM_001374736
975:NM_001374734
971:NM_001374730
967:NM_001374729
963:NM_001374722
952:
937:NM_001144771
933:NM_001144770
929:NM_001144769
910:
891:
867:
848:
824:
805:
785:
780:
645:cytoskeleton
286:
279:
115:External IDs
74:
15:
2451:PDB gallery
1815:(5): e496.
1766:(1): e389.
650:microtubule
605:cell cortex
245:56,954,830
232:56,457,987
93:Identifiers
2486:Categories
1288:, May 2017
1264:References
610:Z discdkac
290:(ortholog)
128:HomoloGene
1858:Autophagy
1038:NP_899236
1034:NP_056363
1030:NP_001714
959:NM_183380
955:NM_020388
945:NM_015548
941:NM_001723
771:Orthologs
525:cytoplasm
136:GeneCards
2358:Genomics
2201:33902783
1934:12168954
1888:26043942
1839:32802955
1790:32042917
1741:38465459
1706:17849487
1665:20415295
1657:16341670
1622:11375975
1581:21936565
1546:14581450
1497:10637308
1448:16745491
1440:12482924
1368:Genomics
1284:–
1252:See also
1236:Several
1210:interact
1157:Dystonin
1132:Wikidata
750:Sources:
550:membrane
2502:Plakins
2413:8621649
2378:8575775
2349:8349819
2306:8345227
2277:8010969
2268:1138243
2230:7919656
2193:7818282
2163:3880796
2128:2645368
2098:2579167
2063:2090522
2033:2045679
2004:1717441
1969:1712022
1879:4590603
1830:7413632
1781:6975176
1537:2173519
1388:2276744
1352:2461961
1286:Ensembl
1168:protein
879:UniProt
836:Ensembl
777:Species
756:QuickGO
660:cytosol
655:nucleus
265:pattern
100:Aliases
2411:
2376:
2347:
2340:294919
2337:
2304:
2275:
2265:
2238:324880
2236:
2228:
2199:
2191:
2161:
2126:
2096:
2061:
2031:
2002:
1967:
1932:
1886:
1876:
1837:
1827:
1788:
1778:
1739:
1704:
1663:
1655:
1620:
1579:
1544:
1534:
1495:
1485:
1446:
1438:
1386:
1350:
1343:442765
1340:
1182:plakin
1115:search
1113:PubMed
893:Q03001
793:Entrez
565:H zone
393:BioGPS
224:6p12.1
132:134369
124:113810
2234:S2CID
2197:S2CID
1661:S2CID
1488:14774
1444:S2CID
1226:erbin
1222:MAP1B
1218:DCTN1
1212:with
1187:actin
1160:(DST)
786:Mouse
781:Human
752:Amigo
288:Mouse
281:Human
228:Start
161:Human
2469:2iak
2409:PMID
2374:PMID
2345:PMID
2302:PMID
2273:PMID
2226:PMID
2189:PMID
2159:PMID
2124:PMID
2094:PMID
2059:PMID
2029:PMID
2000:PMID
1965:PMID
1930:PMID
1884:PMID
1835:PMID
1786:PMID
1737:PMID
1702:PMID
1653:PMID
1618:PMID
1577:PMID
1542:PMID
1493:PMID
1436:PMID
1384:PMID
1348:PMID
1224:and
1175:gene
590:axon
271:Bgee
219:Band
178:Chr.
120:OMIM
77:3GJO
58:RCSB
55:PDBe
2399:doi
2395:271
2366:doi
2335:PMC
2327:doi
2294:doi
2290:101
2263:PMC
2255:doi
2218:doi
2181:doi
2177:286
2149:doi
2116:doi
2084:doi
2051:doi
2021:doi
1990:doi
1986:266
1955:doi
1951:266
1920:doi
1874:PMC
1866:doi
1825:PMC
1817:doi
1776:PMC
1768:doi
1729:doi
1692:doi
1645:doi
1608:doi
1604:276
1569:doi
1532:PMC
1524:doi
1520:163
1483:PMC
1475:doi
1428:doi
1424:116
1376:doi
1338:PMC
1330:doi
1238:Dst
1196:to
1172:DST
1121:n/a
1106:n/a
1084:n/a
1003:n/a
911:n/a
868:n/a
825:n/a
807:667
368:n/a
241:End
144:OMA
140:DST
107:DST
48:PDB
24:DST
2488::
2407:.
2393:.
2389:.
2372:.
2362:29
2360:.
2343:.
2333:.
2323:92
2321:.
2317:.
2300:.
2288:.
2271:.
2261:.
2249:.
2232:.
2224:.
2212:.
2195:.
2187:.
2175:.
2157:.
2145:84
2143:.
2139:.
2122:.
2112:92
2110:.
2092:.
2080:84
2078:.
2074:.
2057:.
2047:45
2045:.
2027:.
2017:96
2015:.
1998:.
1984:.
1980:.
1963:.
1949:.
1945:.
1928:.
1914:.
1910:.
1882:.
1872:.
1862:11
1860:.
1856:.
1833:.
1823:.
1811:.
1807:.
1784:.
1774:.
1762:.
1758:.
1735:.
1725:37
1723:.
1700:.
1688:64
1686:.
1682:.
1659:.
1651:.
1641:16
1639:.
1616:.
1602:.
1598:.
1575:.
1565:10
1563:.
1540:.
1530:.
1518:.
1514:.
1491:.
1481:.
1471:11
1469:.
1465:.
1442:.
1434:.
1422:.
1396:^
1382:.
1370:.
1346:.
1336:.
1326:82
1324:.
1320:.
1301:.
1272:^
1228:.
1220:,
1216:,
1177:.
754:/
247:bp
234:bp
142:;
138::
134:;
130::
126:;
122::
2444:e
2437:t
2430:v
2415:.
2401::
2380:.
2368::
2351:.
2329::
2308:.
2296::
2279:.
2257::
2240:.
2220::
2214:5
2203:.
2183::
2165:.
2151::
2130:.
2118::
2100:.
2086::
2065:.
2053::
2035:.
2023::
2006:.
1992::
1971:.
1957::
1936:.
1922::
1916:9
1890:.
1868::
1841:.
1819::
1813:6
1792:.
1770::
1764:6
1743:.
1731::
1708:.
1694::
1667:.
1647::
1624:.
1610::
1583:.
1571::
1548:.
1526::
1499:.
1477::
1450:.
1430::
1407:.
1390:.
1378::
1372:8
1354:.
1332::
1305:.
163:)
146::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
