244:
221:
118:
143:
250:
149:
1249:
993:
This gene encodes a subunit of dynactin, a component of the cytoplasmic dynein motor machinery involved in minus-end-directed transport. The encoded protein is a component of the pointed-end subcomplex and is thought to bind membranous cargo. A pseudogene of this gene is located on the long arm of
257:
156:
704:
685:
79:
1323:
1294:
1313:
1071:
1053:
243:
927:
920:
220:
1040:
1019:
1318:
142:
117:
1036:
1118:"Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end"
1092:
1015:
59:
994:
chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
256:
155:
1287:
249:
148:
1157:
Parisi G, Fornasari MS, Echave J (March 2004). "Dynactins p25 and p27 are predicted to adopt the LbetaH fold".
749:
67:
730:
1280:
131:
1205:
46:
878:
874:
823:
819:
1194:"Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls"
1182:
1116:
Eckley DM, Gill SR, Melkonian KA, Bingham JB, Goodson HV, Heuser JE, et al. (October 1999).
91:
1192:
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, et al. (June 2007).
903:
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39:
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1307:
1260:
514:
1186:
71:
329:
108:
615:
antigen processing and presentation of exogenous peptide antigen via MHC class II
95:
1076:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1058:
National Center for
Biotechnology Information, U.S. National Library of Medicine
412:
228:
125:
75:
649:
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83:
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1178:
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967:
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1217:
962:
983:
761:
716:
935:
671:
1248:
634:
630:
1256:
987:
63:
600:
endoplasmic reticulum to Golgi vesicle-mediated transport
319:
1268:
484:
896:
867:
841:
812:
423:
dentate gyrus of hippocampal formation granule cell
1032:
1030:
1028:
1011:
1009:
1007:
266:
165:
16:Protein-coding gene in the species Homo sapiens
1037:GRCm38: Ensembl release 89: ENSMUSG00000030868
1288:
8:
1016:GRCh38: Ensembl release 89: ENSG00000166847
1295:
1281:
645:
510:
307:
206:
103:
1225:
1141:
1087:
1085:
1003:
986:that in humans is encoded by the DCTN5
20:
271:
232:
227:
170:
129:
124:
7:
1245:
1243:
1267:. You can help Knowledge (XXG) by
893:
864:
838:
809:
785:
766:
740:
721:
695:
676:
489:
407:
345:
324:
14:
1247:
620:coronary vasculature development
255:
248:
242:
219:
154:
147:
141:
116:
1093:"Entrez Gene: Dynactin 5 (p25)"
1324:Human chromosome 16 gene stubs
610:ventricular septum development
564:chromosome, centromeric region
473:More reference expression data
1:
1171:10.1016/S0014-5793(04)00165-6
240:
139:
1314:Genes on human chromosome 16
1122:The Journal of Cell Biology
369:stromal cell of endometrium
1340:
1242:
439:medial ganglionic eminence
397:mucosa of transverse colon
1072:"Mouse PubMed Reference:"
1054:"Human PubMed Reference:"
966:
961:
957:
950:
934:
928:Chr 7: 121.73 – 121.75 Mb
915:
900:
871:
860:
845:
816:
805:
792:
788:
773:
769:
760:
747:
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138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
921:Chr 16: 23.64 – 23.68 Mb
435:superior frontal gyrus
1319:Genes mutated in mice
1134:10.1083/jcb.147.2.307
132:Chromosome 16 (human)
373:smooth muscle tissue
234:Chromosome 7 (mouse)
50:, dynactin subunit 5
1218:10.1038/nature05911
1210:2007Natur.447..661B
393:epithelium of colon
385:ganglionic eminence
381:mucosa of esophagus
361:islet of Langerhans
1255:This article on a
750:ENSMUSG00000030868
593:Biological process
537:Cellular component
521:Molecular function
1276:
1275:
1204:(7145): 661–678.
977:
976:
973:
972:
946:
945:
911:
910:
890:
889:
856:
855:
835:
834:
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756:
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737:
736:
711:
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691:
640:
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605:aorta development
505:
504:
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500:
479:
478:
466:
465:
404:
403:
302:
301:
201:
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96:DCTN5 - orthologs
1331:
1297:
1290:
1283:
1251:
1244:
1239:
1229:
1190:
1155:
1145:
1103:
1102:
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1099:
1089:
1080:
1079:
1068:
1062:
1061:
1050:
1044:
1034:
1023:
1013:
980:Dynactin 5 (p25)
959:
958:
930:
923:
906:
894:
885:
865:
861:RefSeq (protein)
851:
839:
830:
810:
786:
767:
741:
722:
696:
677:
646:
559:nuclear membrane
511:
490:
475:
415:
413:Top expressed in
408:
353:
351:Top expressed in
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325:
308:
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259:
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1110:Further reading
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1005:
1000:
968:View/Edit Mouse
963:View/Edit Human
926:
919:
916:Location (UCSC)
902:
881:
877:
873:
847:
826:
822:
818:
731:ENSG00000166847
624:
588:
532:
528:protein binding
471:
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457:
453:
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447:pituitary gland
445:
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210:Gene location (
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107:Gene location (
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45:
38:
17:
12:
11:
5:
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1316:
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1300:
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1128:(2): 307–320.
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451:tail of embryo
448:
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436:
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312:RNA expression
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100:
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56:
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43:
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25:
15:
13:
10:
9:
6:
4:
3:
2:
1336:
1325:
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1311:
1309:
1298:
1293:
1291:
1286:
1284:
1279:
1278:
1272:
1270:
1266:
1262:
1261:chromosome 16
1258:
1253:
1250:
1246:
1240:
1237:
1233:
1228:
1223:
1219:
1215:
1211:
1207:
1203:
1199:
1195:
1188:
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1153:
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1123:
1119:
1109:
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1077:
1073:
1067:
1064:
1059:
1055:
1049:
1046:
1042:
1038:
1033:
1031:
1029:
1025:
1021:
1017:
1012:
1010:
1008:
1004:
997:
995:
991:
989:
985:
981:
969:
964:
960:
956:
953:
949:
942:
940:
937:
933:
929:
925:
922:
918:
914:
907:
905:
899:
895:
892:
886:
884:
880:
876:
870:
866:
863:
859:
852:
850:
844:
840:
837:
831:
829:
825:
821:
815:
811:
808:
806:RefSeq (mRNA)
804:
797:
796:
791:
787:
784:
778:
777:
772:
768:
765:
763:
759:
752:
751:
746:
742:
739:
733:
732:
727:
723:
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718:
714:
707:
706:
701:
697:
694:
688:
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682:
678:
675:
673:
669:
666:
663:
661:
658:
654:
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632:
627:
621:
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550:
547:
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541:
539:
536:
535:
529:
526:
525:
523:
520:
519:
516:
515:Gene ontology
512:
508:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
442:
438:
434:
430:
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414:
409:
406:
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388:
384:
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376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
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338:
334:
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331:
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326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
1269:expanding it
1254:
1201:
1197:
1165:(1–3): 1–4.
1162:
1159:FEBS Letters
1158:
1125:
1121:
1114:
1096:. Retrieved
1075:
1066:
1057:
1048:
992:
979:
978:
901:
879:NP_001186672
875:NP_001185940
872:
846:
824:NM_001199743
820:NM_001199011
817:
793:
774:
748:
729:
703:
684:
664:
659:
569:cytoskeleton
455:cumulus cell
427:right kidney
335:
328:
294:121,748,267
281:121,732,264
55:External IDs
18:
579:nucleoplasm
574:kinetochore
431:granulocyte
273:7|7 F2
193:23,677,472
180:23,641,466
33:Identifiers
1308:Categories
1098:2011-09-20
1043:, May 2017
1022:, May 2017
998:References
584:chromosome
554:centrosome
389:lymph node
339:(ortholog)
76:HomoloGene
1259:on human
904:NP_067621
883:NP_115875
849:NM_021608
828:NM_032486
650:Orthologs
544:cytoplasm
84:GeneCards
1236:17554300
1187:84381211
1179:15043994
1152:10525537
1039:–
1018:–
952:Wikidata
629:Sources:
443:yolk sac
377:monocyte
1227:2719288
1206:Bibcode
1143:2174220
1041:Ensembl
1020:Ensembl
984:protein
762:UniProt
717:Ensembl
656:Species
635:QuickGO
549:cytosol
314:pattern
172:16p12.2
72:1891689
40:Aliases
1234:
1224:
1198:Nature
1185:
1177:
1150:
1140:
938:search
936:PubMed
795:Q9QZB9
776:Q9BTE1
672:Entrez
485:BioGPS
365:rectum
64:612962
1263:is a
1183:S2CID
982:is a
705:59288
686:84516
665:Mouse
660:Human
631:Amigo
459:blood
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
88:DCTN5
80:10998
47:DCTN5
24:DCTN5
1265:stub
1257:gene
1232:PMID
1175:PMID
1148:PMID
988:gene
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
1222:PMC
1214:doi
1202:447
1167:doi
1163:562
1138:PMC
1130:doi
1126:147
493:n/a
290:End
189:End
92:OMA
68:MGI
1310::
1230:.
1220:.
1212:.
1200:.
1196:.
1181:.
1173:.
1161:.
1146:.
1136:.
1124:.
1120:.
1084:^
1074:.
1056:.
1027:^
1006:^
990:.
633:/
296:bp
283:bp
195:bp
182:bp
90:;
86::
82:;
78::
74:;
70::
66:;
62::
1296:e
1289:t
1282:v
1271:.
1238:.
1216::
1208::
1189:.
1169::
1154:.
1132::
1101:.
1078:.
1060:.
214:)
111:)
94::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
