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DPPA3

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This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression,
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Sato M, Kimura T, Kurokawa K, et al. (2002). "Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells".
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Bowles J, Teasdale RP, James K, Koopman P (2004). "Dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours".
835: 1208: 1037:"Human STELLAR, NANOG, and GDF3 genes are expressed in pluripotent cells and map to chromosome 12p13, a hotspot for teratocarcinoma" 715: 856: 822: 132: 107: 914:"Adult tissue-specific expression of a Dppa3-derived retrogene represents a postnatal transcript of pluripotent cell origin" 875:
Nakamura T, Arai Y, Umehara H, et al. (2007). "PGC7/Stella protects against DNA demethylation in early embryogenesis".
818: 57: 145: 138: 949:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" 549: 121: 44: 992:"Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice" 1183: 1146: 1103: 1066: 900: 81: 679: 634: 1175: 1138: 1095: 1058: 1023: 978: 935: 892: 37: 1167: 1128: 1087: 1048: 1013: 1003: 968: 960: 925: 884: 225: 156: 77: 200: 1171: 1018: 991: 973: 948: 440: 435: 430: 425: 420: 404: 399: 394: 389: 373: 1202: 790: 360: 1187: 1070: 1150: 1107: 904: 218: 98: 85: 1117:"Stella is a maternal effect gene required for normal early development in mice" 840:
National Center for Biotechnology Information, U.S. National Library of Medicine
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Clark AT, Rodriguez RT, Bodnar MS, et al. (2004).
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Gerhard DS, Wagner L, Feingold EA, et al. (2004).
48:, STELLA, developmental pluripotency associated 3, Pgc7 330: 426:
protection of DNA demethylation of female pronucleus
693: 672: 648: 627: 1115:Payer B, Saitou M, Barton SC, et al. (2004). 814: 812: 810: 155: 990:Bortvin A, Goodheart M, Liao M, Page DC (2004). 773:Developmental pluripotency-associated protein 3 8: 819:GRCh38: Ensembl release 89: ENSG00000187569 797:loci are located on chromosomes 14 and X. 466: 356: 196: 93: 1132: 1052: 1017: 1007: 972: 929: 851: 849: 431:negative regulation of DNA demethylation 806: 18: 160: 119: 114: 7: 912:Elliman SJ, Wu I, Kemp DM (2006). 690: 669: 645: 624: 602: 583: 559: 540: 516: 497: 421:multicellular organism development 335: 296: 234: 213: 14: 779:that in humans is encoded by the 436:regulation of genetic imprinting 144: 137: 131: 106: 319:More reference expression data 1: 1172:10.1016/S0925-4773(02)00002-3 129: 16:Protein-coding gene in humans 1209:Genes on human chromosome 12 1225: 1054:10.1634/stemcells.22-2-169 374:methylated histone binding 1134:10.1016/j.cub.2003.11.026 836:"Human PubMed Reference:" 762: 757: 753: 746: 727: 710: 697: 676: 665: 652: 631: 620: 609: 605: 590: 586: 577: 566: 562: 547: 543: 534: 523: 519: 504: 500: 491: 476: 469: 465: 449: 359: 355: 343: 338: 329: 316: 303: 299: 246: 237: 207: 199: 195: 178: 165: 128: 105: 96: 92: 55: 52: 42: 35: 30: 26: 21: 931:10.1074/jbc.C500415200 716:Chr 12: 7.71 – 7.72 Mb 441:chromatin organization 1080:Cytogenet. Genome Res 1009:10.1186/1471-213X-4-2 122:Chromosome 12 (human) 965:10.1101/gr.2596504 414:Biological process 383:Cellular component 367:Molecular function 1092:10.1159/000074346 770: 769: 766: 765: 742: 741: 706: 705: 687: 686: 661: 660: 642: 641: 616: 615: 599: 598: 573: 572: 556: 555: 530: 529: 513: 512: 461: 460: 405:female pronucleus 351: 350: 347: 346: 325: 324: 312: 311: 293: 292: 191: 190: 86:DPPA3 - orthologs 1216: 1191: 1154: 1136: 1111: 1074: 1056: 1031: 1021: 1011: 986: 976: 943: 933: 908: 861: 860: 853: 844: 843: 832: 826: 816: 755: 754: 738: 723: 718: 701: 691: 682: 670: 666:RefSeq (protein) 656: 646: 637: 625: 603: 584: 560: 541: 517: 498: 467: 357: 336: 321: 297: 262:ventricular zone 242: 240:Top expressed in 235: 214: 197: 187: 174: 163: 148: 141: 135: 124: 110: 94: 88: 47: 40: 19: 1224: 1223: 1219: 1218: 1217: 1215: 1214: 1213: 1199: 1198: 1196: 1194: 1157: 1114: 1077: 1034: 989: 959:(10B): 2121–7. 946: 911: 889:10.1038/ncb1519 874: 870: 868:Further reading 865: 864: 855: 854: 847: 834: 833: 829: 817: 808: 803: 759:View/Edit Human 736: 721: 714: 711:Location (UCSC) 699: 678: 654: 633: 550:ENSG00000187569 445: 409: 390:male pronucleus 378: 317: 308: 289: 284: 280: 276: 272: 268: 264: 260: 256: 252: 238: 182: 169: 161: 151: 150: 149: 142: 120: 97:Gene location ( 56: 43: 36: 17: 12: 11: 5: 1222: 1220: 1212: 1211: 1201: 1200: 1193: 1192: 1155: 1127:(23): 2110–7. 1112: 1086:(3–4): 261–5. 1075: 1032: 987: 944: 909: 877:Nat. Cell Biol 871: 869: 866: 863: 862: 845: 827: 805: 804: 802: 799: 768: 767: 764: 763: 761: 751: 750: 744: 743: 740: 739: 734: 732: 725: 724: 719: 712: 708: 707: 704: 703: 695: 694: 688: 685: 684: 674: 673: 667: 663: 662: 659: 658: 650: 649: 643: 640: 639: 629: 628: 622: 618: 617: 614: 613: 607: 606: 600: 597: 596: 588: 587: 581: 575: 574: 571: 570: 564: 563: 557: 554: 553: 545: 544: 538: 532: 531: 528: 527: 521: 520: 514: 511: 510: 502: 501: 495: 489: 488: 483: 478: 474: 473: 463: 462: 459: 458: 447: 446: 444: 443: 438: 433: 428: 423: 417: 415: 411: 410: 408: 407: 402: 397: 392: 386: 384: 380: 379: 377: 376: 370: 368: 364: 363: 353: 352: 349: 348: 345: 344: 341: 340: 333: 327: 326: 323: 322: 314: 313: 310: 309: 307: 304: 301: 300: 294: 291: 290: 288: 287: 283: 279: 275: 271: 267: 263: 259: 255: 251: 247: 244: 243: 231: 230: 222: 211: 205: 204: 201:RNA expression 193: 192: 189: 188: 180: 176: 175: 167: 164: 159: 153: 152: 143: 136: 130: 126: 125: 118: 112: 111: 103: 102: 90: 89: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1221: 1210: 1207: 1206: 1204: 1197: 1189: 1185: 1181: 1177: 1173: 1169: 1165: 1161: 1156: 1152: 1148: 1144: 1140: 1135: 1130: 1126: 1122: 1118: 1113: 1109: 1105: 1101: 1097: 1093: 1089: 1085: 1081: 1076: 1072: 1068: 1064: 1060: 1055: 1050: 1047:(2): 169–79. 1046: 1042: 1038: 1033: 1029: 1025: 1020: 1015: 1010: 1005: 1001: 997: 996:BMC Dev. Biol 993: 988: 984: 980: 975: 970: 966: 962: 958: 954: 950: 945: 941: 937: 932: 927: 923: 919: 918:J. Biol. Chem 915: 910: 906: 902: 898: 894: 890: 886: 882: 878: 873: 872: 867: 858: 852: 850: 846: 841: 837: 831: 828: 824: 820: 815: 813: 811: 807: 800: 798: 796: 792: 791:cell division 787: 785: 782: 778: 774: 760: 756: 752: 749: 745: 735: 733: 730: 726: 720: 717: 713: 709: 702: 696: 692: 689: 683: 681: 675: 671: 668: 664: 657: 651: 647: 644: 638: 636: 630: 626: 623: 621:RefSeq (mRNA) 619: 612: 608: 604: 601: 595: 594: 589: 585: 582: 580: 576: 569: 565: 561: 558: 552: 551: 546: 542: 539: 537: 533: 526: 522: 518: 515: 509: 508: 503: 499: 496: 494: 490: 487: 484: 482: 479: 475: 472: 468: 464: 457: 453: 448: 442: 439: 437: 434: 432: 429: 427: 424: 422: 419: 418: 416: 413: 412: 406: 403: 401: 398: 396: 393: 391: 388: 387: 385: 382: 381: 375: 372: 371: 369: 366: 365: 362: 361:Gene ontology 358: 354: 342: 337: 334: 332: 328: 320: 315: 305: 302: 298: 295: 285: 281: 277: 274:muscle tissue 273: 269: 265: 261: 257: 253: 249: 248: 245: 241: 236: 233: 232: 229: 227: 223: 221: 220: 216: 215: 212: 210: 206: 202: 198: 194: 186: 181: 177: 173: 168: 158: 154: 147: 140: 134: 127: 123: 117: 113: 109: 104: 100: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 1195: 1163: 1159: 1124: 1120: 1083: 1079: 1044: 1040: 999: 995: 956: 952: 921: 917: 883:(1): 64–71. 880: 876: 839: 830: 788: 780: 772: 771: 698: 677: 653: 632: 610: 591: 567: 548: 524: 505: 485: 480: 266:right testis 224: 217: 53:External IDs 1166:(1): 91–4. 924:(1): 16–9. 286:right ovary 278:left testis 31:Identifiers 1121:Curr. Biol 1041:Stem Cells 953:Genome Res 825:, May 2017 801:References 795:intronless 228:(ortholog) 183:7,717,559 170:7,711,433 66:HomoloGene 1160:Mech. Dev 680:NP_954980 635:NM_199286 471:Orthologs 395:cytoplasm 74:GeneCards 1203:Category 1188:12877378 1180:11900980 1143:14654002 1100:14684992 1071:38136098 1063:14990856 1028:15018652 983:15489334 940:16291741 897:17143267 821:– 748:Wikidata 450:Sources: 258:duodenum 254:testicle 162:12p13.31 1151:2010581 1108:7005986 905:1947132 823:Ensembl 777:protein 579:UniProt 536:Ensembl 477:Species 456:QuickGO 400:nucleus 203:pattern 38:Aliases 1186:  1178:  1149:  1141:  1106:  1098:  1069:  1061:  1026:  1019:362866 1016:  981:  974:528928 971:  938:  903:  895:  731:search 729:PubMed 593:Q6W0C5 507:359787 493:Entrez 331:BioGPS 70:138483 62:608408 1184:S2CID 1147:S2CID 1104:S2CID 1067:S2CID 1002:: 2. 901:S2CID 781:DPPA3 775:is a 486:Mouse 481:Human 452:Amigo 282:liver 270:blood 250:gonad 226:Mouse 219:Human 166:Start 99:Human 78:DPPA3 45:DPPA3 22:DPPA3 1176:PMID 1139:PMID 1096:PMID 1059:PMID 1024:PMID 979:PMID 936:PMID 893:PMID 784:gene 209:Bgee 157:Band 116:Chr. 58:OMIM 1168:doi 1164:113 1129:doi 1088:doi 1084:101 1049:doi 1014:PMC 1004:doi 969:PMC 961:doi 926:doi 922:281 885:doi 737:n/a 722:n/a 700:n/a 655:n/a 611:n/a 568:n/a 525:n/a 339:n/a 306:n/a 179:End 82:OMA 1205:: 1182:. 1174:. 1162:. 1145:. 1137:. 1125:13 1123:. 1119:. 1102:. 1094:. 1082:. 1065:. 1057:. 1045:22 1043:. 1039:. 1022:. 1012:. 998:. 994:. 977:. 967:. 957:14 955:. 951:. 934:. 920:. 916:. 899:. 891:. 879:. 848:^ 838:. 809:^ 786:. 454:/ 185:bp 172:bp 80:; 76:: 72:; 68:: 64:; 60:: 1190:. 1170:: 1153:. 1131:: 1110:. 1090:: 1073:. 1051:: 1030:. 1006:: 1000:4 985:. 963:: 942:. 928:: 907:. 887:: 881:9 859:. 842:. 101:) 84::

Index

Aliases
DPPA3
OMIM
608408
HomoloGene
138483
GeneCards
DPPA3
OMA
DPPA3 - orthologs
Human
Chromosome 12 (human)
Chr.
Chromosome 12 (human)
Chromosome 12 (human)
Genomic location for DPPA3
Genomic location for DPPA3
Band
bp
bp
RNA expression
Bgee
Human
Mouse
Top expressed in
More reference expression data
BioGPS
Gene ontology
methylated histone binding
male pronucleus

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