Knowledge

DRG1

Source 📝

297: 274: 171: 196: 303: 202: 1699: 50: 310: 209: 787: 768: 132: 1484:
Bandyopadhyay S, Pai SK, Hirota S, et al. (2004). "Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression".
1768: 1744: 1763: 1140: 1122: 296: 987: 273: 1609:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
994: 1656:"The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer" 1234: 1109: 1088: 195: 170: 1105: 47: 1084: 1463:
Bandyopadhyay S, Pai SK, Gross SC, et al. (2003). "The Drg-1 gene suppresses tumor metastasis in prostate cancer".
1199:
Sazuka T, Tomooka Y, Ikawa Y, Noda M, Kumar S (Dec 1992). "DRG: a novel developmentally regulated GTP-binding protein".
112: 1282:
Mahajan MA, Park ST, Sun XH (1996). "Association of a novel GTP binding protein, DRG, with TAL oncogenic proteins".
309: 208: 1737: 302: 201: 1253:
Sazuka T, Kinoshita M, Tomooka Y, et al. (1992). "Expression of DRG during murine embryonic development".
832: 120: 1568:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" 813: 1730: 184: 1618: 1423: 1351: 99: 1642: 1509: 144: 1412:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 970: 949: 923: 902: 1677: 1634: 1597: 1554: 1501: 1472: 1451: 1398: 1369: 1326: 1291: 1270: 1216: 1181: 92: 40: 1381:
Li B, Trueb B (2000). "DRG represents a family of two closely related GTP-binding proteins".
1667: 1626: 1587: 1579: 1544: 1534: 1493: 1441: 1431: 1390: 1359: 1316: 1262: 1208: 1171: 1160:"A novel GTP-binding protein which is selectively repressed in SV40 transformed fibroblasts" 389: 320: 264: 219: 364: 140: 1622: 1427: 1355: 1714: 1592: 1567: 1549: 1522: 1446: 1411: 1394: 1321: 1304: 1176: 1159: 702: 697: 692: 687: 682: 666: 661: 656: 651: 646: 641: 625: 620: 615: 610: 605: 600: 595: 590: 585: 580: 1757: 1710: 1266: 1212: 567: 1513: 124: 1646: 382: 161: 1672: 1655: 148: 1145:
National Center for Biotechnology Information, U.S. National Library of Medicine
1127:
National Center for Biotechnology Information, U.S. National Library of Medicine
465: 281: 178: 128: 1539: 732: 525: 403: 348: 335: 247: 234: 136: 1681: 1638: 1601: 1558: 1505: 1497: 1476: 1455: 1436: 1402: 1373: 1330: 1295: 1274: 1220: 1185: 1034: 1029: 1018: 877: 858: 1630: 1583: 1050: 844: 799: 69: 1002: 754: 1698: 1364: 1339: 1235:"Entrez Gene: DRG1 developmentally regulated GTP binding protein 1" 1523:"A genome annotation-driven approach to cloning the human ORFeome" 717: 713: 1706: 1158:
Schenker T, Lach C, Kessler B, Calderara S, Trueb B (Nov 1994).
1057: 116: 1410:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
372: 103:, NEDD3, developmentally regulated GTP binding protein 1 1718: 1566:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1521:
Collins JE, Wright CL, Edwards CA, et al. (2005).
1654:
Bandyopadhyay S, Wang Y, Zhan R, et al. (2007).
537: 963: 942: 916: 895: 1101: 1099: 1097: 1080: 1078: 1076: 1338:Dunham I, Shimizu N, Roe BA, et al. (1999). 698:positive regulation of microtubule polymerization 319: 218: 1047:Developmentally-regulated GTP-binding protein 1 16:Protein-coding gene in the species Homo sapiens 1305:"SCL binds the human homologue of DRG in vivo" 1106:GRCm38: Ensembl release 89: ENSMUSG00000020457 1738: 8: 1085:GRCh38: Ensembl release 89: ENSG00000185721 1745: 1731: 728: 563: 446:Skeletal muscle tissue of rectus abdominis 360: 259: 156: 58: 1671: 1591: 1548: 1538: 1445: 1435: 1363: 1340:"The DNA sequence of human chromosome 22" 1320: 1175: 1072: 703:regulation of mitotic spindle assembly 18: 324: 285: 280: 223: 182: 177: 7: 1695: 1693: 960: 939: 913: 892: 868: 849: 823: 804: 778: 759: 683:multicellular organism development 542: 460: 398: 377: 14: 1053:that in humans is encoded by the 1697: 308: 301: 295: 272: 207: 200: 194: 169: 1769:Human chromosome 22 gene stubs 526:More reference expression data 1: 1673:10.1158/0008-5472.CAN-06-0943 1395:10.1016/s0167-4781(00)00025-7 1322:10.1016/s0167-4889(98)00129-3 1255:Biochem. Biophys. Res. Commun 1177:10.1016/S0021-9258(18)47271-7 293: 192: 1764:Genes on human chromosome 22 1717:. You can help Knowledge by 1416:Proc. Natl. Acad. Sci. U.S.A 1267:10.1016/0006-291X(92)91568-B 1213:10.1016/0006-291X(92)91567-A 688:transcription, DNA-templated 591:transcription factor binding 1785: 1692: 1303:Zhao XF, Aplan PD (1999). 1201:Biochem Biophys Res Commun 476:medial ganglionic eminence 1141:"Mouse PubMed Reference:" 1123:"Human PubMed Reference:" 1033: 1028: 1024: 1017: 1001: 982: 967: 946: 935: 920: 899: 888: 875: 871: 856: 852: 843: 830: 826: 811: 807: 798: 785: 781: 766: 762: 753: 738: 731: 727: 711: 601:identical protein binding 566: 562: 550: 545: 536: 523: 472: 463: 450:quadriceps femoris muscle 410: 401: 371: 363: 359: 342: 329: 292: 271: 262: 258: 241: 228: 191: 168: 159: 155: 110: 107: 97: 90: 85: 66: 61: 44: 39: 34: 30: 26: 21: 1540:10.1186/gb-2004-5-10-r84 442:tibialis anterior muscle 988:Chr 22: 31.4 – 31.53 Mb 693:cytoplasmic translation 508:internal carotid artery 1498:10.1038/sj.onc.1207734 1437:10.1073/pnas.242603899 1383:Biochim. Biophys. Acta 1309:Biochim. Biophys. Acta 995:Chr 11: 3.14 – 3.22 Mb 426:triceps brachii muscle 621:potassium ion binding 287:Chromosome 11 (mouse) 185:Chromosome 22 (human) 62:List of PDB id codes 35:Available structures 1631:10.1038/nature04209 1623:2005Natur.437.1173R 1428:2002PNAS...9916899M 1356:1999Natur.402..489D 611:microtubule binding 1705:This article on a 1584:10.1101/gr.2596504 833:ENSMUSG00000020457 676:Biological process 635:Cellular component 616:hydrolase activity 581:nucleotide binding 574:Molecular function 1726: 1725: 1422:(26): 16899–903. 1044: 1043: 1040: 1039: 1013: 1012: 978: 977: 957: 956: 931: 930: 910: 909: 884: 883: 865: 864: 839: 838: 820: 819: 794: 793: 775: 774: 723: 722: 626:metal ion binding 558: 557: 554: 553: 532: 531: 519: 518: 457: 456: 355: 354: 254: 253: 81: 80: 77: 76: 45:Ortholog search: 1776: 1747: 1740: 1733: 1701: 1694: 1685: 1675: 1666:(24): 11983–90. 1650: 1617:(7062): 1173–8. 1605: 1595: 1562: 1552: 1542: 1517: 1480: 1459: 1449: 1439: 1406: 1389:(1–3): 196–204. 1377: 1367: 1350:(6761): 489–95. 1334: 1324: 1299: 1278: 1239: 1238: 1231: 1225: 1224: 1196: 1190: 1189: 1179: 1170:(41): 25447–53. 1155: 1149: 1148: 1137: 1131: 1130: 1119: 1113: 1103: 1092: 1082: 1026: 1025: 997: 990: 973: 961: 952: 940: 936:RefSeq (protein) 926: 914: 905: 893: 869: 850: 824: 805: 779: 760: 729: 564: 543: 528: 512:ventricular zone 468: 466:Top expressed in 461: 406: 404:Top expressed in 399: 378: 361: 351: 338: 327: 312: 305: 299: 288: 276: 260: 250: 237: 226: 211: 204: 198: 187: 173: 157: 151: 149:DRG1 - orthologs 102: 95: 72: 59: 53: 32: 31: 19: 1784: 1783: 1779: 1778: 1777: 1775: 1774: 1773: 1754: 1753: 1752: 1751: 1690: 1688: 1653: 1608: 1578:(10B): 2121–7. 1565: 1520: 1492:(33): 5675–81. 1483: 1462: 1409: 1380: 1337: 1302: 1290:(11): 2343–50. 1281: 1252: 1248: 1246:Further reading 1243: 1242: 1233: 1232: 1228: 1198: 1197: 1193: 1157: 1156: 1152: 1139: 1138: 1134: 1121: 1120: 1116: 1104: 1095: 1083: 1074: 1069: 1063: 1035:View/Edit Mouse 1030:View/Edit Human 993: 986: 983:Location (UCSC) 969: 948: 922: 901: 814:ENSG00000185721 707: 671: 630: 606:GTPase activity 596:protein binding 524: 515: 510: 506: 502: 498: 494: 490: 486: 482: 478: 464: 453: 448: 444: 440: 436: 432: 428: 424: 420: 416: 402: 346: 333: 325: 315: 314: 313: 306: 286: 263:Gene location ( 245: 232: 224: 214: 213: 212: 205: 183: 160:Gene location ( 111: 98: 91: 68: 46: 17: 12: 11: 5: 1782: 1780: 1772: 1771: 1766: 1756: 1755: 1750: 1749: 1742: 1735: 1727: 1724: 1723: 1702: 1687: 1686: 1651: 1606: 1563: 1518: 1481: 1460: 1407: 1378: 1365:10.1038/990031 1335: 1300: 1279: 1249: 1247: 1244: 1241: 1240: 1226: 1191: 1150: 1132: 1114: 1093: 1071: 1070: 1068: 1065: 1042: 1041: 1038: 1037: 1032: 1022: 1021: 1015: 1014: 1011: 1010: 1008: 1006: 999: 998: 991: 984: 980: 979: 976: 975: 965: 964: 958: 955: 954: 944: 943: 937: 933: 932: 929: 928: 918: 917: 911: 908: 907: 897: 896: 890: 886: 885: 882: 881: 873: 872: 866: 863: 862: 854: 853: 847: 841: 840: 837: 836: 828: 827: 821: 818: 817: 809: 808: 802: 796: 795: 792: 791: 783: 782: 776: 773: 772: 764: 763: 757: 751: 750: 745: 740: 736: 735: 725: 724: 721: 720: 709: 708: 706: 705: 700: 695: 690: 685: 679: 677: 673: 672: 670: 669: 664: 659: 654: 649: 644: 638: 636: 632: 631: 629: 628: 623: 618: 613: 608: 603: 598: 593: 588: 583: 577: 575: 571: 570: 560: 559: 556: 555: 552: 551: 548: 547: 540: 534: 533: 530: 529: 521: 520: 517: 516: 514: 513: 509: 505: 501: 497: 493: 489: 485: 481: 477: 473: 470: 469: 458: 455: 454: 452: 451: 447: 443: 439: 438:deltoid muscle 435: 431: 427: 423: 422:male germ cell 419: 415: 411: 408: 407: 395: 394: 386: 375: 369: 368: 365:RNA expression 357: 356: 353: 352: 344: 340: 339: 331: 328: 323: 317: 316: 307: 300: 294: 290: 289: 284: 278: 277: 269: 268: 256: 255: 252: 251: 243: 239: 238: 230: 227: 222: 216: 215: 206: 199: 193: 189: 188: 181: 175: 174: 166: 165: 153: 152: 109: 105: 104: 96: 88: 87: 83: 82: 79: 78: 75: 74: 64: 63: 55: 54: 43: 37: 36: 28: 27: 24: 23: 15: 13: 10: 9: 6: 4: 3: 2: 1781: 1770: 1767: 1765: 1762: 1761: 1759: 1748: 1743: 1741: 1736: 1734: 1729: 1728: 1722: 1720: 1716: 1712: 1711:chromosome 22 1708: 1703: 1700: 1696: 1691: 1683: 1679: 1674: 1669: 1665: 1661: 1657: 1652: 1648: 1644: 1640: 1636: 1632: 1628: 1624: 1620: 1616: 1612: 1607: 1603: 1599: 1594: 1589: 1585: 1581: 1577: 1573: 1569: 1564: 1560: 1556: 1551: 1546: 1541: 1536: 1532: 1528: 1524: 1519: 1515: 1511: 1507: 1503: 1499: 1495: 1491: 1487: 1482: 1478: 1474: 1471:(8): 1731–6. 1470: 1466: 1461: 1457: 1453: 1448: 1443: 1438: 1433: 1429: 1425: 1421: 1417: 1413: 1408: 1404: 1400: 1396: 1392: 1388: 1384: 1379: 1375: 1371: 1366: 1361: 1357: 1353: 1349: 1345: 1341: 1336: 1332: 1328: 1323: 1318: 1315:(1): 109–14. 1314: 1310: 1306: 1301: 1297: 1293: 1289: 1285: 1280: 1276: 1272: 1268: 1264: 1260: 1256: 1251: 1250: 1245: 1236: 1230: 1227: 1222: 1218: 1214: 1210: 1207:(1): 363–70. 1206: 1202: 1195: 1192: 1187: 1183: 1178: 1173: 1169: 1165: 1161: 1154: 1151: 1146: 1142: 1136: 1133: 1128: 1124: 1118: 1115: 1111: 1107: 1102: 1100: 1098: 1094: 1090: 1086: 1081: 1079: 1077: 1073: 1066: 1064: 1061: 1059: 1056: 1052: 1048: 1036: 1031: 1027: 1023: 1020: 1016: 1009: 1007: 1004: 1000: 996: 992: 989: 985: 981: 974: 972: 966: 962: 959: 953: 951: 945: 941: 938: 934: 927: 925: 919: 915: 912: 906: 904: 898: 894: 891: 889:RefSeq (mRNA) 887: 880: 879: 874: 870: 867: 861: 860: 855: 851: 848: 846: 842: 835: 834: 829: 825: 822: 816: 815: 810: 806: 803: 801: 797: 790: 789: 784: 780: 777: 771: 770: 765: 761: 758: 756: 752: 749: 746: 744: 741: 737: 734: 730: 726: 719: 715: 710: 704: 701: 699: 696: 694: 691: 689: 686: 684: 681: 680: 678: 675: 674: 668: 665: 663: 660: 658: 655: 653: 650: 648: 645: 643: 640: 639: 637: 634: 633: 627: 624: 622: 619: 617: 614: 612: 609: 607: 604: 602: 599: 597: 594: 592: 589: 587: 584: 582: 579: 578: 576: 573: 572: 569: 568:Gene ontology 565: 561: 549: 544: 541: 539: 535: 527: 522: 511: 507: 503: 499: 495: 491: 487: 483: 479: 475: 474: 471: 467: 462: 459: 449: 445: 441: 437: 433: 429: 425: 421: 417: 413: 412: 409: 405: 400: 397: 396: 393: 391: 387: 385: 384: 380: 379: 376: 374: 370: 366: 362: 358: 350: 345: 341: 337: 332: 326:11|11 A1 322: 318: 311: 304: 298: 291: 283: 279: 275: 270: 266: 261: 257: 249: 244: 240: 236: 231: 221: 217: 210: 203: 197: 190: 186: 180: 176: 172: 167: 163: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 114: 106: 101: 94: 89: 84: 73: 71: 65: 60: 57: 56: 52: 49: 42: 38: 33: 29: 25: 20: 1719:expanding it 1704: 1689: 1663: 1659: 1614: 1610: 1575: 1571: 1530: 1526: 1489: 1485: 1468: 1464: 1419: 1415: 1386: 1382: 1347: 1343: 1312: 1308: 1287: 1283: 1261:(1): 371–7. 1258: 1254: 1229: 1204: 1200: 1194: 1167: 1163: 1153: 1144: 1135: 1126: 1117: 1062: 1054: 1046: 1045: 968: 947: 921: 900: 876: 857: 831: 812: 786: 767: 747: 742: 662:nuclear body 480:spermatocyte 418:right testis 388: 381: 108:External IDs 67: 1533:(10): R84. 1527:Genome Biol 1164:J Biol Chem 586:GTP binding 414:left testis 246:31,530,634 233:31,399,604 86:Identifiers 1758:Categories 1660:Cancer Res 1572:Genome Res 1465:Cancer Res 1112:, May 2017 1091:, May 2017 1067:References 484:blastocyst 392:(ortholog) 347:3,216,415 334:3,137,360 129:HomoloGene 1709:on human 971:NP_031905 950:NP_004138 924:NM_007879 903:NM_004147 733:Orthologs 642:cytoplasm 488:spermatid 137:GeneCards 1682:17178897 1639:16189514 1602:15489334 1559:15461802 1514:24392094 1506:15184886 1486:Oncogene 1477:12702552 1456:12477932 1403:10760581 1374:10591208 1284:Oncogene 1108:– 1087:– 1019:Wikidata 712:Sources: 652:membrane 647:polysome 504:epiblast 1647:4427026 1619:Bibcode 1424:Bibcode 1352:Bibcode 1331:9824680 1296:8649774 1275:1280421 1221:1449490 1186:7929244 1110:Ensembl 1089:Ensembl 1051:protein 845:UniProt 800:Ensembl 739:Species 718:QuickGO 667:nucleus 657:cytosol 367:pattern 225:22q12.2 125:1343297 93:Aliases 1680:  1645:  1637:  1611:Nature 1600:  1593:528928 1590:  1557:  1550:545604 1547:  1512:  1504:  1475:  1454:  1447:139241 1444:  1401:  1372:  1344:Nature 1329:  1294:  1273:  1219:  1184:  1005:search 1003:PubMed 878:P32233 859:Q9Y295 755:Entrez 538:BioGPS 500:embryo 496:morula 492:morula 430:glutes 117:603952 1713:is a 1643:S2CID 1510:S2CID 1049:is a 788:13494 748:Mouse 743:Human 714:Amigo 434:sperm 390:Mouse 383:Human 330:Start 265:Mouse 229:Start 162:Human 1715:stub 1707:gene 1678:PMID 1635:PMID 1598:PMID 1555:PMID 1502:PMID 1473:PMID 1452:PMID 1399:PMID 1387:1491 1370:PMID 1327:PMID 1313:1448 1292:PMID 1271:PMID 1217:PMID 1182:PMID 1058:gene 1055:DRG1 769:4733 373:Bgee 321:Band 282:Chr. 220:Band 179:Chr. 141:DRG1 133:3060 113:OMIM 100:DRG1 70:2EKI 51:RCSB 48:PDBe 22:DRG1 1668:doi 1627:doi 1615:437 1588:PMC 1580:doi 1545:PMC 1535:doi 1494:doi 1442:PMC 1432:doi 1391:doi 1360:doi 1348:402 1317:doi 1263:doi 1259:189 1209:doi 1205:189 1172:doi 1168:269 546:n/a 343:End 242:End 145:OMA 121:MGI 41:PDB 1760:: 1676:. 1664:66 1662:. 1658:. 1641:. 1633:. 1625:. 1613:. 1596:. 1586:. 1576:14 1574:. 1570:. 1553:. 1543:. 1529:. 1525:. 1508:. 1500:. 1490:23 1488:. 1469:63 1467:. 1450:. 1440:. 1430:. 1420:99 1418:. 1414:. 1397:. 1385:. 1368:. 1358:. 1346:. 1342:. 1325:. 1311:. 1307:. 1288:12 1286:. 1269:. 1257:. 1215:. 1203:. 1180:. 1166:. 1162:. 1143:. 1125:. 1096:^ 1075:^ 1060:. 716:/ 349:bp 336:bp 248:bp 235:bp 143:; 139:: 135:; 131:: 127:; 123:: 119:; 115:: 1746:e 1739:t 1732:v 1721:. 1684:. 1670:: 1649:. 1629:: 1621:: 1604:. 1582:: 1561:. 1537:: 1531:5 1516:. 1496:: 1479:. 1458:. 1434:: 1426:: 1405:. 1393:: 1376:. 1362:: 1354:: 1333:. 1319:: 1298:. 1277:. 1265:: 1237:. 1223:. 1211:: 1188:. 1174:: 1147:. 1129:. 267:) 164:) 147::

Index

PDB
PDBe
RCSB
2EKI
Aliases
DRG1
OMIM
603952
MGI
1343297
HomoloGene
3060
GeneCards
DRG1
OMA
DRG1 - orthologs
Human
Chromosome 22 (human)
Chr.
Chromosome 22 (human)
Chromosome 22 (human)
Genomic location for DRG1
Genomic location for DRG1
Band
bp
bp
Mouse
Chromosome 11 (mouse)
Chr.
Chromosome 11 (mouse)

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.