316:
293:
190:
215:
2628:
322:
221:
31:
2643:
2671:
1416:
type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. Three transcript variants encoding three different isoforms have been found for this gene.
57:
2035:
Bui TD, Beier DR, Jonssen M, Smith K, Dorrington SM, Kaklamanis L, Kearney L, Regan R, Sussman DJ, Harris AL (1997). "cDNA cloning of a human dishevelled DVL-3 gene, mapping to 3q27, and expression in human breast and colon carcinomas".
2580:
1928:
Pizzuti A, Novelli G, Mari A, Ratti A, Colosimo A, Amati F, Penso D, Sangiuolo F, Calabrese G, Palka G, Silani V, Gennarelli M, Mingarelli R, Scarlato G, Scambler P, Dallapiccola B (1996).
2627:
2067:"Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin"
329:
228:
1562:
Pizzuti A, Amati F, Calabrese G, Mari A, Colosimo A, Silani V, Giardino L, Ratti A, Penso D, CalzĂ L, Palka G, Scarlato G, Novelli G, Dallapiccola B (Jan 1997).
1076:
151:
1057:
2483:"Identification of genomic organisation, sequence variants and analysis of the role of the human dishevelled 1 gene in late onset Alzheimer's disease"
1451:
2712:
2607:
1544:
1526:
2731:
1413:
2387:"beta-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins"
315:
1311:
1304:
292:
1606:
2642:
1513:
1492:
1509:
1769:
Inobe M, Katsube Ki, Miyagoe Y, Nabeshima Yi, Takeda S (Dec 1999). "Identification of EPS8 as a Dvl1-associated molecule".
214:
189:
54:
2110:"DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability"
1722:"DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability"
1488:
1409:
131:
1895:"The Drosophila segment polarity gene dishevelled encodes a novel protein required for response to the wingless signal"
1426:
2440:"Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1"
1930:"Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome"
328:
227:
2705:
1564:"cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene"
2153:"Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization"
2600:
321:
220:
1121:
139:
1860:"Runnin' with the Dvl: proteins that associate with Dsh/Dvl and their significance to Wnt signal transduction"
2352:"Axin-dependent phosphorylation of the adenomatous polyposis coli protein mediated by casein kinase 1epsilon"
1102:
2736:
1671:"SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability"
2698:
2593:
2529:
2398:
1817:
203:
118:
2196:"Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1"
1622:"Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1"
1404:
specification. DVL1 is a candidate gene for processes involved in cell transformations involved in
1287:
1258:
1232:
1228:
1203:
2469:
1988:
1397:
163:
2636:: STRUCTURAL BASIS OF THE RECOGNITION OF THE DISHEVELLED DEP DOMAIN IN THE WNT SIGNALING PATHWAY
1283:
1262:
1224:
1199:
1195:
1191:
2239:"Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription"
2576:
2557:
2504:
2461:
2426:
2373:
2338:
2295:
2260:
2225:
2182:
2139:
2096:
2053:
2023:
1980:
1963:
Steitz SA, Tsang M, Sussman DJ (1997). "Wnt-mediated relocalization of dishevelled proteins".
1951:
1916:
1881:
1835:
1786:
1751:
1702:
1651:
1585:
111:
47:
2682:
1620:
Li L, Yuan H, Weaver CD, Mao J, Farr GH, Sussman DJ, Jonkers J, Kimelman D, Wu D (Aug 1999).
2547:
2537:
2494:
2451:
2416:
2406:
2363:
2328:
2320:
2285:
2250:
2215:
2207:
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2129:
2121:
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2013:
1972:
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1825:
1778:
1741:
1733:
1692:
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1641:
1633:
1575:
408:
339:
283:
238:
2307:
Hino S, Kishida S, Michiue T, Fukui A, Sakamoto I, Takada S, Asashima M, Kikuchi A (2001).
1400:, acting as a transducer molecule for developmental processes, including segmentation and
383:
159:
2274:"Endogenous protein kinase CK2 participates in Wnt signaling in mammary epithelial cells"
2194:
Li L, Yuan H, Weaver CD, Mao J, Farr GH, Sussman DJ, Jonkers J, Kimelman D, Wu D (1999).
2533:
2402:
1821:
2220:
2195:
2177:
2152:
2091:
2066:
1946:
1929:
1697:
1670:
1646:
1621:
1393:
2552:
2518:"Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex"
2517:
2456:
2439:
2134:
2109:
1830:
1805:
1746:
1721:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
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916:
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836:
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624:
619:
614:
609:
604:
599:
30:
2725:
2421:
2386:
2333:
2308:
1405:
586:
2473:
1992:
401:
180:
2385:
Chen W, Hu LA, Semenov MV, Yanagawa S, Kikuchi A, Lefkowitz RJ, Miller WE (2002).
2324:
143:
167:
1549:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1531:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1464:
1389:
932:
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
2211:
1806:"Identification of three novel Smad binding proteins involved in cell polarity"
1637:
484:
2499:
2482:
2309:"Inhibition of the Wnt signaling pathway by Idax, a novel Dvl-binding protein"
2082:
1401:
300:
197:
147:
2151:
Fagotto F, Jho Eh, Zeng L, Kurth T, Joos T, Kaufmann C, Costantini F (1999).
1021:
544:
422:
367:
354:
266:
253:
155:
2561:
2542:
2508:
2465:
2430:
2411:
2377:
2368:
2351:
2342:
2299:
2290:
2273:
2264:
2255:
2238:
2229:
2186:
2143:
2049:
2018:
2001:
1885:
1876:
1859:
1839:
1790:
1782:
1755:
1706:
1655:
2168:
2125:
2100:
2057:
2027:
1984:
1955:
1920:
1737:
1589:
1580:
1563:
1351:
1346:
1720:
Kishida S, Yamamoto H, Hino S, Ikeda S, Kishida M, Kikuchi A (Jun 1999).
1687:
1335:
1166:
1147:
1911:
1894:
2678:
1976:
1367:
1133:
1088:
2670:
2002:"Human dishevelled genes constitute a DHR-containing multigene family"
88:
84:
80:
76:
2108:
Kishida S, Yamamoto H, Hino S, Ikeda S, Kishida M, Kikuchi A (1999).
2065:
Ikeda S, Kishida S, Yamamoto H, Murai H, Koyama S, Kikuchi A (1998).
1319:
1043:
122:, DVL, DVL1L1, DVL1P1, DRS2, dishevelled segment polarity protein 1
1433:
1006:
1002:
1445:
1439:
1374:
135:
2589:
2585:
827:
planar cell polarity pathway involved in neural tube closure
1607:"Entrez Gene: DVL1 dishevelled, dsh homolog 1 (Drosophila)"
2516:
Gao ZH, Seeling JM, Hill V, Yochum A, Virshup DM (2002).
972:
positive regulation of protein localization to presynapse
1804:
Warner DR, Pisano MM, Roberts EA, Greene RM (Mar 2003).
962:
positive regulation of excitatory postsynaptic potential
917:
convergent extension involved in neural plate elongation
391:
2686:
947:
positive regulation of canonical Wnt signaling pathway
922:
negative regulation of canonical Wnt signaling pathway
907:
skeletal muscle acetylcholine-gated channel clustering
987:
positive regulation of neuron projection arborization
556:
882:
positive regulation of neuron projection development
1276:
1251:
1217:
1184:
852:
Wnt signaling pathway, planar cell polarity pathway
837:
positive regulation of transcription, DNA-templated
1505:
1503:
1501:
1484:
1482:
1480:
1364:Segment polarity protein dishevelled homolog DVL-1
338:
237:
1510:GRCm38: Ensembl release 89: ENSMUSG00000029071
937:convergent extension involved in organogenesis
787:negative regulation of protein kinase activity
772:positive regulation of protein phosphorylation
762:negative regulation of protein phosphorylation
2706:
2601:
8:
1893:Klingensmith J, Nusse R, Perrimon N (1994).
952:beta-catenin destruction complex disassembly
842:positive regulation of Wnt signaling pathway
1489:GRCh38: Ensembl release 89: ENSG00000107404
2713:
2699:
2608:
2594:
2586:
1669:Kim MJ, Chia IV, Costantini F (Nov 2008).
1017:
582:
441:Skeletal muscle tissue of rectus abdominis
379:
278:
175:
65:
2551:
2541:
2498:
2455:
2420:
2410:
2367:
2332:
2289:
2254:
2219:
2176:
2133:
2090:
2017:
1945:
1910:
1875:
1829:
1745:
1696:
1686:
1645:
1579:
1452:Mothers against decapentaplegic homolog 3
992:regulation of synaptic vesicle exocytosis
2651:: Solution Structure of mDvl1 PDZ domain
2350:Rubinfeld B, Tice DA, Polakis P (2001).
1601:
1599:
2623:
2481:Russ C, Lovestone S, Powell JF (2002).
2272:Song DH, Sussman DJ, Seldin DC (2000).
1476:
817:negative regulation of protein binding
20:
2237:Strovel ET, Wu D, Sussman DJ (2000).
767:regulation of neurotransmitter levels
757:regulation of protein phosphorylation
343:
304:
299:
242:
201:
196:
7:
2667:
2665:
877:cytoplasmic microtubule organization
977:non-canonical Wnt signaling pathway
857:protein localization to microtubule
2685:. You can help Knowledge (XXG) by
1392:gene (dsh), encodes a cytoplasmic
1273:
1248:
1214:
1181:
1157:
1138:
1112:
1093:
1067:
1048:
862:neuromuscular junction development
847:multicellular organism development
812:transcription by RNA polymerase II
561:
479:
417:
396:
14:
1370:that in humans is encoded by the
777:intracellular signal transduction
736:Schaffer collateral - CA1 synapse
2669:
2641:
2626:
327:
320:
314:
291:
226:
219:
213:
188:
29:
1385:DVL1, the human homolog of the
897:canonical Wnt signaling pathway
892:protein localization to nucleus
2581:Atlas of Genetics and Oncology
2438:Habas R, Kato Y, He X (2002).
1965:In Vitro Cell. Dev. Biol. Anim
545:More reference expression data
469:right hemisphere of cerebellum
1:
2457:10.1016/S0092-8674(01)00614-6
2325:10.1128/MCB.21.1.330-342.2001
2038:Biochem. Biophys. Res. Commun
2000:Semënov MV, Snyder M (1997).
1831:10.1016/s0014-5793(03)00155-8
1771:Biochem. Biophys. Res. Commun
957:dendritic spine morphogenesis
312:
211:
16:Human protein and coding gene
2522:Proc. Natl. Acad. Sci. U.S.A
2391:Proc. Natl. Acad. Sci. U.S.A
2732:Genes on human chromosome 1
1414:Charcot–Marie–Tooth disease
2753:
2664:
927:neurotransmitter secretion
2621:
1545:"Mouse PubMed Reference:"
1527:"Human PubMed Reference:"
1350:
1345:
1341:
1334:
1318:
1312:Chr 4: 155.93 – 155.94 Mb
1299:
1280:
1255:
1244:
1221:
1188:
1177:
1164:
1160:
1145:
1141:
1132:
1119:
1115:
1100:
1096:
1087:
1074:
1070:
1055:
1051:
1042:
1027:
1020:
1016:
1000:
615:identical protein binding
585:
581:
569:
564:
555:
542:
495:medullary collecting duct
491:
482:
429:
420:
390:
382:
378:
361:
348:
311:
290:
281:
277:
260:
247:
210:
187:
178:
174:
129:
126:
116:
109:
104:
73:
68:
51:
46:
41:
37:
28:
23:
2212:10.1093/emboj/18.15.4233
1638:10.1093/emboj/18.15.4233
1410:Schwartz–Jampel syndrome
982:postsynapse organization
666:microtubule cytoskeleton
515:Rostral migratory stream
2083:10.1093/emboj/17.5.1371
1425:DVL1 has been shown to
872:neural tube development
711:clathrin-coated vesicle
656:lateral plasma membrane
523:vastus lateralis muscle
2681:-related article is a
2543:10.1073/pnas.032468199
2412:10.1073/pnas.211572798
2369:10.1074/jbc.M105148200
2291:10.1074/jbc.M909107199
2256:10.1074/jbc.275.4.2399
2050:10.1006/bbrc.1997.7500
2019:10.1006/geno.1997.4713
1877:10.1006/dbio.2002.0869
1783:10.1006/bbrc.1999.1782
792:dendrite morphogenesis
625:protein kinase binding
453:pancreatic ductal cell
2500:10.1038/sj/mp/4000941
2169:10.1083/jcb.145.4.741
2126:10.1128/mcb.19.6.4414
1738:10.1128/mcb.19.6.4414
1305:Chr 1: 1.34 – 1.35 Mb
867:cochlea morphogenesis
807:Wnt signaling pathway
802:protein stabilization
741:glutamatergic synapse
1688:10.1096/fj.08-113910
912:collateral sprouting
797:synapse organization
726:postsynaptic density
600:beta-catenin binding
437:gastrocnemius muscle
345:4 E2|4 87.61 cM
306:Chromosome 4 (mouse)
204:Chromosome 1 (human)
69:List of PDB id codes
42:Available structures
2534:2002PNAS...99.1182G
2403:2001PNAS...9814889C
1912:10.1101/gad.8.1.118
1858:Wharton KA (2003).
1822:2003FEBSL.539..167W
1581:10.1093/hmg/5.7.953
967:presynapse assembly
942:prepulse inhibition
822:receptor clustering
731:cytoplasmic vesicle
1977:10.1007/BF02723007
1398:cell proliferation
1122:ENSMUSG00000029071
750:Biological process
691:neuronal cell body
634:Cellular component
593:Molecular function
461:thoracic diaphragm
449:right frontal lobe
2694:
2693:
2659:
2658:
1934:Am. J. Hum. Genet
1361:
1360:
1357:
1356:
1330:
1329:
1295:
1294:
1270:
1269:
1240:
1239:
1211:
1210:
1173:
1172:
1154:
1153:
1128:
1127:
1109:
1108:
1083:
1082:
1064:
1063:
1012:
1011:
701:neuron projection
577:
576:
573:
572:
551:
550:
538:
537:
476:
475:
374:
373:
273:
272:
100:
99:
96:
95:
52:Ortholog search:
2744:
2715:
2708:
2701:
2673:
2666:
2645:
2630:
2610:
2603:
2596:
2587:
2565:
2555:
2545:
2512:
2502:
2477:
2459:
2434:
2424:
2414:
2397:(26): 14889–94.
2381:
2371:
2362:(42): 39037–45.
2346:
2336:
2303:
2293:
2268:
2258:
2233:
2223:
2190:
2180:
2147:
2137:
2104:
2094:
2061:
2031:
2021:
1996:
1959:
1949:
1924:
1914:
1889:
1879:
1844:
1843:
1833:
1801:
1795:
1794:
1766:
1760:
1759:
1749:
1717:
1711:
1710:
1700:
1690:
1666:
1660:
1659:
1649:
1617:
1611:
1610:
1603:
1594:
1593:
1583:
1559:
1553:
1552:
1541:
1535:
1534:
1523:
1517:
1507:
1496:
1486:
1343:
1342:
1314:
1307:
1290:
1274:
1265:
1249:
1245:RefSeq (protein)
1235:
1215:
1206:
1182:
1158:
1139:
1113:
1094:
1068:
1049:
1018:
605:frizzled binding
583:
562:
547:
507:substantia nigra
487:
485:Top expressed in
480:
425:
423:Top expressed in
418:
397:
380:
370:
357:
346:
331:
324:
318:
307:
295:
279:
269:
256:
245:
230:
223:
217:
206:
192:
176:
170:
168:DVL1 - orthologs
121:
114:
91:
66:
60:
39:
38:
33:
21:
2752:
2751:
2747:
2746:
2745:
2743:
2742:
2741:
2722:
2721:
2720:
2719:
2662:
2660:
2655:
2652:
2646:
2637:
2631:
2617:
2614:
2573:
2568:
2515:
2487:Mol. Psychiatry
2480:
2437:
2384:
2349:
2313:Mol. Cell. Biol
2306:
2284:(31): 23790–7.
2271:
2249:(4): 2399–403.
2236:
2206:(15): 4233–40.
2193:
2150:
2114:Mol. Cell. Biol
2107:
2064:
2034:
1999:
1962:
1927:
1892:
1857:
1853:
1851:Further reading
1848:
1847:
1816:(1–3): 167–73.
1803:
1802:
1798:
1768:
1767:
1763:
1726:Mol. Cell. Biol
1719:
1718:
1714:
1681:(11): 3785–94.
1668:
1667:
1663:
1632:(15): 4233–40.
1619:
1618:
1614:
1605:
1604:
1597:
1561:
1560:
1556:
1543:
1542:
1538:
1525:
1524:
1520:
1508:
1499:
1487:
1478:
1473:
1461:
1423:
1396:that regulates
1383:
1352:View/Edit Mouse
1347:View/Edit Human
1310:
1303:
1300:Location (UCSC)
1286:
1282:
1261:
1257:
1231:
1227:
1223:
1202:
1198:
1194:
1190:
1103:ENSG00000107404
996:
902:social behavior
745:
721:dendritic spine
676:plasma membrane
651:Wnt signalosome
629:
610:protein binding
543:
534:
529:
527:ascending aorta
525:
521:
517:
513:
509:
505:
503:renal corpuscle
501:
497:
483:
472:
467:
463:
459:
455:
451:
447:
443:
439:
435:
433:muscle of thigh
421:
365:
352:
344:
334:
333:
332:
325:
305:
282:Gene location (
264:
251:
243:
233:
232:
231:
224:
202:
179:Gene location (
130:
117:
110:
75:
53:
17:
12:
11:
5:
2750:
2748:
2740:
2739:
2734:
2724:
2723:
2718:
2717:
2710:
2703:
2695:
2692:
2691:
2674:
2657:
2656:
2654:
2653:
2647:
2640:
2638:
2632:
2625:
2622:
2619:
2618:
2615:
2613:
2612:
2605:
2598:
2590:
2584:
2583:
2572:
2571:External links
2569:
2567:
2566:
2513:
2478:
2435:
2382:
2347:
2304:
2269:
2234:
2191:
2148:
2120:(6): 4414–22.
2105:
2077:(5): 1371–84.
2062:
2032:
1997:
1960:
1925:
1890:
1854:
1852:
1849:
1846:
1845:
1796:
1761:
1732:(6): 4414–22.
1712:
1661:
1612:
1595:
1554:
1536:
1518:
1497:
1475:
1474:
1472:
1469:
1468:
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1460:
1457:
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1455:
1449:
1443:
1437:
1422:
1419:
1394:phosphoprotein
1382:
1379:
1359:
1358:
1355:
1354:
1349:
1339:
1338:
1332:
1331:
1328:
1327:
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1301:
1297:
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1252:
1246:
1242:
1241:
1238:
1237:
1219:
1218:
1212:
1209:
1208:
1186:
1185:
1179:
1175:
1174:
1171:
1170:
1162:
1161:
1155:
1152:
1151:
1143:
1142:
1136:
1130:
1129:
1126:
1125:
1117:
1116:
1110:
1107:
1106:
1098:
1097:
1091:
1085:
1084:
1081:
1080:
1072:
1071:
1065:
1062:
1061:
1053:
1052:
1046:
1040:
1039:
1034:
1029:
1025:
1024:
1014:
1013:
1010:
1009:
998:
997:
995:
994:
989:
984:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
887:axon extension
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
753:
751:
747:
746:
744:
743:
738:
733:
728:
723:
718:
713:
708:
703:
698:
693:
688:
683:
678:
673:
668:
663:
658:
653:
648:
643:
637:
635:
631:
630:
628:
627:
622:
620:enzyme binding
617:
612:
607:
602:
596:
594:
590:
589:
579:
578:
575:
574:
571:
570:
567:
566:
559:
553:
552:
549:
548:
540:
539:
536:
535:
533:
532:
528:
524:
520:
516:
512:
508:
504:
500:
496:
492:
489:
488:
477:
474:
473:
471:
470:
466:
462:
458:
457:body of tongue
454:
450:
446:
442:
438:
434:
430:
427:
426:
414:
413:
405:
394:
388:
387:
384:RNA expression
376:
375:
372:
371:
363:
359:
358:
350:
347:
342:
336:
335:
326:
319:
313:
309:
308:
303:
297:
296:
288:
287:
275:
274:
271:
270:
262:
258:
257:
249:
246:
241:
235:
234:
225:
218:
212:
208:
207:
200:
194:
193:
185:
184:
172:
171:
128:
124:
123:
115:
107:
106:
102:
101:
98:
97:
94:
93:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
15:
13:
10:
9:
6:
4:
3:
2:
2749:
2738:
2737:Protein stubs
2735:
2733:
2730:
2729:
2727:
2716:
2711:
2709:
2704:
2702:
2697:
2696:
2690:
2688:
2684:
2680:
2675:
2672:
2668:
2663:
2650:
2644:
2639:
2635:
2629:
2624:
2620:
2611:
2606:
2604:
2599:
2597:
2592:
2591:
2588:
2582:
2578:
2575:
2574:
2570:
2563:
2559:
2554:
2549:
2544:
2539:
2535:
2531:
2528:(3): 1182–7.
2527:
2523:
2519:
2514:
2510:
2506:
2501:
2496:
2492:
2488:
2484:
2479:
2475:
2471:
2467:
2463:
2458:
2453:
2450:(7): 843–54.
2449:
2445:
2441:
2436:
2432:
2428:
2423:
2418:
2413:
2408:
2404:
2400:
2396:
2392:
2388:
2383:
2379:
2375:
2370:
2365:
2361:
2357:
2356:J. Biol. Chem
2353:
2348:
2344:
2340:
2335:
2330:
2326:
2322:
2319:(1): 330–42.
2318:
2314:
2310:
2305:
2301:
2297:
2292:
2287:
2283:
2279:
2278:J. Biol. Chem
2275:
2270:
2266:
2262:
2257:
2252:
2248:
2244:
2243:J. Biol. Chem
2240:
2235:
2231:
2227:
2222:
2217:
2213:
2209:
2205:
2201:
2197:
2192:
2188:
2184:
2179:
2174:
2170:
2166:
2163:(4): 741–56.
2162:
2158:
2154:
2149:
2145:
2141:
2136:
2131:
2127:
2123:
2119:
2115:
2111:
2106:
2102:
2098:
2093:
2088:
2084:
2080:
2076:
2072:
2068:
2063:
2059:
2055:
2051:
2047:
2043:
2039:
2033:
2029:
2025:
2020:
2015:
2012:(2): 302–10.
2011:
2007:
2003:
1998:
1994:
1990:
1986:
1982:
1978:
1974:
1970:
1966:
1961:
1957:
1953:
1948:
1943:
1939:
1935:
1931:
1926:
1922:
1918:
1913:
1908:
1905:(1): 118–30.
1904:
1900:
1896:
1891:
1887:
1883:
1878:
1873:
1869:
1865:
1861:
1856:
1855:
1850:
1841:
1837:
1832:
1827:
1823:
1819:
1815:
1811:
1807:
1800:
1797:
1792:
1788:
1784:
1780:
1777:(1): 216–21.
1776:
1772:
1765:
1762:
1757:
1753:
1748:
1743:
1739:
1735:
1731:
1727:
1723:
1716:
1713:
1708:
1704:
1699:
1694:
1689:
1684:
1680:
1676:
1672:
1665:
1662:
1657:
1653:
1648:
1643:
1639:
1635:
1631:
1627:
1623:
1616:
1613:
1608:
1602:
1600:
1596:
1591:
1587:
1582:
1577:
1573:
1569:
1568:Hum Mol Genet
1565:
1558:
1555:
1550:
1546:
1540:
1537:
1532:
1528:
1522:
1519:
1515:
1511:
1506:
1504:
1502:
1498:
1494:
1490:
1485:
1483:
1481:
1477:
1470:
1466:
1463:
1462:
1458:
1453:
1450:
1447:
1444:
1441:
1438:
1435:
1432:
1431:
1430:
1428:
1420:
1418:
1415:
1411:
1407:
1406:neuroblastoma
1403:
1399:
1395:
1391:
1388:
1380:
1378:
1376:
1373:
1369:
1365:
1353:
1348:
1344:
1340:
1337:
1333:
1326:
1324:
1321:
1317:
1313:
1309:
1306:
1302:
1298:
1291:
1289:
1285:
1279:
1275:
1272:
1266:
1264:
1260:
1254:
1250:
1247:
1243:
1236:
1234:
1230:
1226:
1220:
1216:
1213:
1207:
1205:
1201:
1197:
1193:
1187:
1183:
1180:
1178:RefSeq (mRNA)
1176:
1169:
1168:
1163:
1159:
1156:
1150:
1149:
1144:
1140:
1137:
1135:
1131:
1124:
1123:
1118:
1114:
1111:
1105:
1104:
1099:
1095:
1092:
1090:
1086:
1079:
1078:
1073:
1069:
1066:
1060:
1059:
1054:
1050:
1047:
1045:
1041:
1038:
1035:
1033:
1030:
1026:
1023:
1019:
1015:
1008:
1004:
999:
993:
990:
988:
985:
983:
980:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
948:
945:
943:
940:
938:
935:
933:
930:
928:
925:
923:
920:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
832:axon guidance
830:
828:
825:
823:
820:
818:
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
788:
785:
783:
780:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
754:
752:
749:
748:
742:
739:
737:
734:
732:
729:
727:
724:
722:
719:
717:
714:
712:
709:
707:
704:
702:
699:
697:
694:
692:
689:
687:
684:
682:
679:
677:
674:
672:
669:
667:
664:
662:
659:
657:
654:
652:
649:
647:
644:
642:
639:
638:
636:
633:
632:
626:
623:
621:
618:
616:
613:
611:
608:
606:
603:
601:
598:
597:
595:
592:
591:
588:
587:Gene ontology
584:
580:
568:
563:
560:
558:
554:
546:
541:
530:
526:
522:
518:
514:
511:barrel cortex
510:
506:
502:
498:
494:
493:
490:
486:
481:
478:
468:
464:
460:
456:
452:
448:
445:apex of heart
444:
440:
436:
432:
431:
428:
424:
419:
416:
415:
412:
410:
406:
404:
403:
399:
398:
395:
393:
389:
385:
381:
377:
369:
364:
360:
356:
351:
341:
337:
330:
323:
317:
310:
302:
298:
294:
289:
285:
280:
276:
268:
263:
259:
255:
250:
240:
236:
229:
222:
216:
209:
205:
199:
195:
191:
186:
182:
177:
173:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
125:
120:
113:
108:
103:
92:
90:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
19:
2687:expanding it
2676:
2661:
2648:
2633:
2525:
2521:
2493:(1): 104–9.
2490:
2486:
2447:
2443:
2394:
2390:
2359:
2355:
2316:
2312:
2281:
2277:
2246:
2242:
2203:
2199:
2160:
2157:J. Cell Biol
2156:
2117:
2113:
2074:
2070:
2044:(2): 510–6.
2041:
2037:
2009:
2005:
1971:(7): 441–5.
1968:
1964:
1940:(4): 722–9.
1937:
1933:
1902:
1898:
1867:
1863:
1813:
1809:
1799:
1774:
1770:
1764:
1729:
1725:
1715:
1678:
1674:
1664:
1629:
1625:
1615:
1574:(7): 953–8.
1571:
1567:
1557:
1548:
1539:
1530:
1521:
1424:
1421:Interactions
1386:
1384:
1371:
1363:
1362:
1288:NP_001343310
1281:
1259:NP_001317240
1256:
1233:NM_001356381
1229:NM_001302342
1222:
1204:NM_001330311
1189:
1165:
1146:
1120:
1101:
1075:
1056:
1036:
1031:
782:axonogenesis
519:motor neuron
407:
400:
366:155,943,760
353:155,931,859
127:External IDs
74:
18:
2616:PDB gallery
1870:(1): 1–17.
1465:Dishevelled
1390:dishevelled
706:microtubule
671:growth cone
499:Paneth cell
105:Identifiers
2726:Categories
1516:, May 2017
1495:, May 2017
1471:References
1402:neuroblast
1387:Drosophila
716:presynapse
411:(ortholog)
265:1,349,418
252:1,335,276
148:HomoloGene
1899:Genes Dev
1864:Dev. Biol
1810:FEBS Lett
1284:NP_034221
1263:NP_004412
1225:NM_010091
1200:NM_182779
1196:NM_181870
1192:NM_004421
1022:Orthologs
641:cytoplasm
156:GeneCards
2562:11818547
2509:11803455
2474:16894557
2466:11779461
2431:11742073
2378:11487578
2343:11113207
2300:10806215
2265:10644691
2230:10428961
2187:10330403
2144:10330181
2006:Genomics
1993:20740333
1886:12490194
1840:12650946
1791:10581192
1756:10330181
1707:18632848
1656:10428961
1512:–
1491:–
1459:See also
1427:interact
1381:Function
1336:Wikidata
1001:Sources:
696:dendrite
661:membrane
465:amygdala
2679:protein
2579:on the
2530:Bibcode
2399:Bibcode
2221:1171499
2178:2133179
2101:9482734
2092:1170485
2058:9344861
2028:9192851
1985:8856345
1956:8644734
1947:1914677
1921:8288125
1818:Bibcode
1698:2574027
1675:FASEB J
1647:1171499
1590:8817329
1514:Ensembl
1493:Ensembl
1368:protein
1134:UniProt
1089:Ensembl
1028:Species
1007:QuickGO
681:synapse
646:cytosol
386:pattern
244:1p36.33
112:Aliases
2560:
2553:122164
2550:
2507:
2472:
2464:
2429:
2419:
2376:
2341:
2331:
2298:
2263:
2228:
2218:
2200:EMBO J
2185:
2175:
2142:
2135:104400
2132:
2099:
2089:
2071:EMBO J
2056:
2026:
1991:
1983:
1954:
1944:
1919:
1884:
1838:
1789:
1754:
1747:104400
1744:
1705:
1695:
1654:
1644:
1626:EMBO J
1588:
1448:, and
1429:with:
1408:. The
1322:search
1320:PubMed
1167:P51141
1148:O14640
1044:Entrez
557:BioGPS
136:601365
2677:This
2470:S2CID
2422:64954
2334:88806
1989:S2CID
1434:AXIN1
1366:is a
1077:13542
1037:Mouse
1032:Human
1003:Amigo
531:fossa
409:Mouse
402:Human
349:Start
284:Mouse
248:Start
181:Human
152:20926
144:94941
2683:stub
2649:1mc7
2634:1fsh
2577:DVL1
2558:PMID
2505:PMID
2462:PMID
2444:Cell
2427:PMID
2374:PMID
2339:PMID
2296:PMID
2261:PMID
2226:PMID
2183:PMID
2140:PMID
2097:PMID
2054:PMID
2024:PMID
1981:PMID
1952:PMID
1917:PMID
1882:PMID
1836:PMID
1787:PMID
1752:PMID
1703:PMID
1652:PMID
1586:PMID
1446:EPS8
1440:DVL3
1412:and
1375:gene
1372:DVL1
1058:1855
686:axon
392:Bgee
340:Band
301:Chr.
239:Band
198:Chr.
160:DVL1
132:OMIM
119:DVL1
89:3PZ8
85:2KAW
81:1MC7
77:1FSH
58:RCSB
55:PDBe
24:DVL1
2548:PMC
2538:doi
2495:doi
2452:doi
2448:107
2417:PMC
2407:doi
2364:doi
2360:276
2329:PMC
2321:doi
2286:doi
2282:275
2251:doi
2247:275
2216:PMC
2208:doi
2173:PMC
2165:doi
2161:145
2130:PMC
2122:doi
2087:PMC
2079:doi
2046:doi
2042:239
2014:doi
1973:doi
1942:PMC
1907:doi
1872:doi
1868:253
1826:doi
1814:539
1779:doi
1775:266
1742:PMC
1734:doi
1693:PMC
1683:doi
1642:PMC
1634:doi
1576:doi
565:n/a
362:End
261:End
164:OMA
140:MGI
48:PDB
2728::
2556:.
2546:.
2536:.
2526:99
2524:.
2520:.
2503:.
2489:.
2485:.
2468:.
2460:.
2446:.
2442:.
2425:.
2415:.
2405:.
2395:98
2393:.
2389:.
2372:.
2358:.
2354:.
2337:.
2327:.
2317:21
2315:.
2311:.
2294:.
2280:.
2276:.
2259:.
2245:.
2241:.
2224:.
2214:.
2204:18
2202:.
2198:.
2181:.
2171:.
2159:.
2155:.
2138:.
2128:.
2118:19
2116:.
2112:.
2095:.
2085:.
2075:17
2073:.
2069:.
2052:.
2040:.
2022:.
2010:42
2008:.
2004:.
1987:.
1979:.
1969:32
1967:.
1950:.
1938:58
1936:.
1932:.
1915:.
1901:.
1897:.
1880:.
1866:.
1862:.
1834:.
1824:.
1812:.
1808:.
1785:.
1773:.
1750:.
1740:.
1730:19
1728:.
1724:.
1701:.
1691:.
1679:22
1677:.
1673:.
1650:.
1640:.
1630:18
1628:.
1624:.
1598:^
1584:.
1570:.
1566:.
1547:.
1529:.
1500:^
1479:^
1377:.
1005:/
368:bp
355:bp
267:bp
254:bp
162:;
158::
154:;
150::
146:;
142::
138:;
134::
87:,
83:,
79:,
2714:e
2707:t
2700:v
2689:.
2609:e
2602:t
2595:v
2564:.
2540::
2532::
2511:.
2497::
2491:7
2476:.
2454::
2433:.
2409::
2401::
2380:.
2366::
2345:.
2323::
2302:.
2288::
2267:.
2253::
2232:.
2210::
2189:.
2167::
2146:.
2124::
2103:.
2081::
2060:.
2048::
2030:.
2016::
1995:.
1975::
1958:.
1923:.
1909::
1903:8
1888:.
1874::
1842:.
1828::
1820::
1793:.
1781::
1758:.
1736::
1709:.
1685::
1658:.
1636::
1609:.
1592:.
1578::
1572:5
1551:.
1533:.
1454:.
1442:,
1436:,
286:)
183:)
166::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
