316:
293:
2005:
190:
215:
1975:
31:
322:
221:
1990:
2033:
57:
1227:
Jiang J, Yu L, Huang X, Chen X, Li D, Zhang Y, Tang L, Zhao S (Dec 2001). "Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients".
2004:
1785:
Pérez-González A, Rodriguez A, Huarte M, et al. (2007). "hCLE/CGI-99, a human protein that interacts with the influenza virus polymerase, is a mRNA transcription modulator".
1551:
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides".
1843:
Kang HC, Kim IJ, Kim K, et al. (2007). "km23, a transforming growth factor-beta signaling component, is infrequently mutated in human colorectal and gastric cancers".
329:
228:
1748:
Campbell IG, Phillips WA, Choong DY (2006). "Genetic and epigenetic analysis of the putative tumor suppressor km23 in primary ovarian, breast, and colorectal cancers".
1974:
1336:"Cloning and Functional Analysis of cDNAs with Open Reading Frames for 300 Previously Undefined Genes Expressed in CD34+ Hematopoietic Stem/Progenitor Cells"
1814:
Liu JF, Wang ZX, Wang XQ, et al. (2006). "Crystal structure of human dynein light chain Dnlc2A: structural insights into the interaction with IC74".
796:
777:
151:
1263:
Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005).
2102:
1872:
Wanschers B, van de
Vorstenbosch R, Fransen J, et al. (2008). "Rab6 family proteins interact with the dynein light chain protein DYNLRB1".
2078:
2097:
1954:
1209:
1191:
1588:
Saito Y, Doi K, Yamagishi N, et al. (2004). "Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems".
315:
1047:
1040:
1703:
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
292:
1315:
1178:
1157:
2013:: Solution NMR structure of protein dynein light chain 2A, cytoplasmic; Northeast structural genomics consortium TARGET HR2106
214:
189:
1174:
54:
1153:
131:
328:
227:
321:
220:
2071:
1989:
1947:
1129:
841:
139:
1662:"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)"
822:
2064:
203:
1940:
1712:
1468:
1390:
118:
1019:
998:
994:
990:
982:
952:
931:
913:
909:
905:
1773:
1736:
1576:
163:
1457:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
1023:
986:
956:
921:
917:
1909:
1889:
1860:
1831:
1802:
1765:
1728:
1691:
1648:
1605:
1568:
1539:
1496:
1443:
1408:
1365:
1294:
1245:
111:
47:
2048:
1422:"The roadblock light chain binds a novel region of the cytoplasmic Dynein intermediate chain"
159:
1881:
1852:
1823:
1794:
1757:
1720:
1681:
1673:
1638:
1630:
1597:
1560:
1529:
1521:
1486:
1476:
1433:
1398:
1355:
1347:
1284:
1276:
1237:
408:
339:
283:
238:
383:
30:
1856:
1716:
1472:
1394:
1289:
1264:
1686:
1661:
1643:
1618:
1534:
1509:
1491:
1456:
1360:
1335:
1241:
711:
706:
701:
696:
691:
675:
670:
665:
660:
655:
650:
645:
640:
635:
630:
614:
609:
604:
599:
2091:
2044:
1918:
586:
1777:
1580:
143:
1740:
1125:
401:
180:
1761:
167:
1214:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1196:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1827:
1601:
484:
1798:
300:
197:
147:
1983:: Solution structure of a mouse cytoplasmic Roadblock/LC7 dynein light chain
1121:
741:
544:
422:
367:
354:
266:
253:
155:
1893:
1864:
1835:
1806:
1769:
1732:
1695:
1652:
1609:
1572:
1543:
1500:
1481:
1447:
1438:
1421:
1412:
1369:
1298:
1249:
1280:
1087:
1082:
1071:
886:
867:
1724:
1525:
122:, BITH, BLP, DNCL2A, DNLC2A, ROBLD1, dynein light chain roadblock-type 1
1923:
1913:
1677:
1634:
1103:
853:
808:
1351:
88:
84:
80:
76:
1885:
1117:
1055:
763:
2032:
1403:
1378:
1564:
1379:"The DNA sequence and comparative analysis of human chromosome 20"
1132:, suggesting that this gene may be involved in tumor progression.
726:
722:
2040:
1124:
protein that is capable of binding intermediate chain proteins.
1110:
135:
1936:
1932:
1908:
Overview of all the structural information available in the
1619:"A Protein Interaction Framework for Human mRNA Degradation"
1316:"Entrez Gene: DYNLRB1 dynein, light chain, roadblock-type 1"
1455:
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1377:
Deloukas P, Matthews LH, Ashurst J, et al. (2002).
391:
2052:
1660:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
1420:
Susalka SJ, Nikulina K, Salata MW, et al. (2002).
1508:
Huang YS, Carson JH, Barbarese E, Richter JD (2003).
556:
1012:
975:
945:
904:
519:
dentate gyrus of hippocampal formation granule cell
1510:"Facilitation of dendritic mRNA transport by CPEB"
1170:
1168:
1166:
1149:
1147:
1145:
702:intraciliary transport involved in cilium assembly
338:
237:
18:Protein-coding gene in the species Homo sapiens
1175:GRCm38: Ensembl release 89: ENSMUSG00000047459
2072:
1948:
1922:(Dynein light chain roadblock-type 1) at the
8:
1334:Zhang QH, Ye M, Wu XY, et al. (2001).
1154:GRCh38: Ensembl release 89: ENSG00000125971
2079:
2065:
1955:
1941:
1933:
901:
737:
582:
379:
278:
175:
65:
1685:
1642:
1533:
1490:
1480:
1437:
1402:
1359:
1288:
1310:
1308:
1970:
1141:
1116:This gene is a member of the roadblock
1128:of this gene has been associated with
20:
343:
304:
299:
242:
201:
196:
7:
2029:
2027:
1857:10.1016/j.cancergencyto.2007.02.004
1100:Dynein light chain roadblock-type 1
2051:. You can help Knowledge (XXG) by
1009:
972:
942:
877:
858:
832:
813:
787:
768:
561:
479:
417:
396:
14:
1265:"Cytoplasmic dynein nomenclature"
1120:light chain family and encodes a
1106:that in humans is encoded by the
615:dynein intermediate chain binding
2031:
2003:
1988:
1973:
327:
320:
314:
291:
226:
219:
213:
188:
29:
1617:Lehner B, Sanderson CM (2004).
2103:Human chromosome 20 gene stubs
545:More reference expression data
445:right hemisphere of cerebellum
1:
1816:Biochem. Biophys. Res. Commun
1762:10.1158/1078-0432.CCR-06-0800
1590:Biochem. Biophys. Res. Commun
1242:10.1016/S0378-1119(01)00787-9
312:
211:
2098:Genes on human chromosome 20
1998:: Solution structure of km23
1461:Proc. Natl. Acad. Sci. U.S.A
610:cytoskeletal motor activity
2119:
2026:
1828:10.1016/j.bbrc.2006.08.161
1602:10.1016/j.bbrc.2003.12.108
712:response to light stimulus
697:microtubule-based movement
666:cytoplasmic dynein complex
605:microtubule motor activity
1968:
1799:10.1016/j.jmb.2006.07.085
1210:"Mouse PubMed Reference:"
1192:"Human PubMed Reference:"
1130:hepatocellular carcinomas
1086:
1081:
1077:
1070:
1054:
1048:Chr 2: 155.08 – 155.09 Mb
1035:
1016:
979:
968:
949:
928:
897:
884:
880:
865:
861:
852:
839:
835:
820:
816:
807:
794:
790:
775:
771:
762:
747:
740:
736:
720:
585:
581:
569:
564:
555:
542:
491:
482:
441:anterior cingulate cortex
429:
420:
390:
382:
378:
361:
348:
311:
290:
281:
277:
260:
247:
210:
187:
178:
174:
129:
126:
116:
109:
104:
73:
68:
51:
46:
41:
37:
28:
23:
1874:Cell Motil. Cytoskeleton
1041:Chr 20: 34.52 – 34.54 Mb
1845:Cancer Genet. Cytogenet
1482:10.1073/pnas.242603899
1439:10.1074/jbc.M205510200
507:neural layer of retina
1281:10.1083/jcb.200508078
204:Chromosome 20 (human)
461:left coronary artery
306:Chromosome 2 (mouse)
69:List of PDB id codes
42:Available structures
1725:10.1038/nature04209
1717:2005Natur.437.1173R
1526:10.1101/gad.1053003
1473:2002PNAS...9916899M
1395:2001Natur.414..865D
531:ganglionic eminence
457:islet of Langerhans
168:DYNLRB1 - orthologs
2039:This article on a
1678:10.1101/gr.2596504
1635:10.1101/gr.2122004
842:ENSMUSG00000047459
685:Biological process
624:Cellular component
593:Molecular function
499:supraoptic nucleus
437:right frontal lobe
2060:
2059:
2021:
2020:
1467:(26): 16899–903.
1352:10.1101/gr.140200
1097:
1096:
1093:
1092:
1066:
1065:
1031:
1030:
1006:
1005:
964:
963:
939:
938:
893:
892:
874:
873:
848:
847:
829:
828:
803:
802:
784:
783:
732:
731:
577:
576:
573:
572:
551:
550:
538:
537:
476:
475:
374:
373:
273:
272:
100:
99:
96:
95:
52:Ortholog search:
2110:
2081:
2074:
2067:
2035:
2028:
2007:
1992:
1977:
1957:
1950:
1943:
1934:
1897:
1886:10.1002/cm.20254
1868:
1839:
1810:
1781:
1750:Clin. Cancer Res
1744:
1711:(7062): 1173–8.
1699:
1689:
1656:
1646:
1613:
1584:
1547:
1537:
1504:
1494:
1484:
1451:
1441:
1432:(36): 32939–46.
1416:
1406:
1389:(6866): 865–71.
1373:
1363:
1320:
1319:
1312:
1303:
1302:
1292:
1260:
1254:
1253:
1224:
1218:
1217:
1206:
1200:
1199:
1188:
1182:
1172:
1161:
1151:
1079:
1078:
1050:
1043:
1026:
1010:
1001:
973:
969:RefSeq (protein)
959:
943:
934:
902:
878:
859:
833:
814:
788:
769:
738:
676:outer dynein arm
583:
562:
547:
511:seminal vesicula
495:genital tubercle
487:
485:Top expressed in
480:
465:popliteal artery
425:
423:Top expressed in
418:
397:
380:
370:
357:
346:
331:
324:
318:
307:
295:
279:
269:
256:
245:
230:
223:
217:
206:
192:
176:
170:
121:
114:
91:
66:
60:
39:
38:
33:
21:
2118:
2117:
2113:
2112:
2111:
2109:
2108:
2107:
2088:
2087:
2086:
2085:
2024:
2022:
2017:
2014:
2008:
1999:
1993:
1984:
1978:
1964:
1961:
1930:
1905:
1900:
1871:
1842:
1813:
1784:
1747:
1702:
1672:(10B): 2121–7.
1659:
1616:
1587:
1553:Nat. Biotechnol
1550:
1507:
1454:
1419:
1404:10.1038/414865a
1376:
1346:(10): 1546–60.
1333:
1329:
1327:Further reading
1324:
1323:
1314:
1313:
1306:
1262:
1261:
1257:
1236:(1–2): 103–13.
1226:
1225:
1221:
1208:
1207:
1203:
1190:
1189:
1185:
1173:
1164:
1152:
1143:
1138:
1088:View/Edit Mouse
1083:View/Edit Human
1046:
1039:
1036:Location (UCSC)
1022:
1018:
997:
993:
989:
985:
981:
955:
951:
930:
924:
920:
916:
912:
908:
823:ENSG00000125971
716:
692:visual behavior
680:
619:
600:protein binding
543:
534:
529:
525:
523:ascending aorta
521:
517:
513:
509:
505:
501:
497:
483:
472:
469:tibial arteries
467:
463:
459:
455:
451:
447:
443:
439:
435:
433:Brodmann area 9
421:
365:
352:
344:
334:
333:
332:
325:
305:
282:Gene location (
264:
251:
243:
233:
232:
231:
224:
202:
179:Gene location (
130:
117:
110:
75:
53:
19:
12:
11:
5:
2116:
2114:
2106:
2105:
2100:
2090:
2089:
2084:
2083:
2076:
2069:
2061:
2058:
2057:
2036:
2019:
2018:
2016:
2015:
2009:
2002:
2000:
1994:
1987:
1985:
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1972:
1969:
1966:
1965:
1962:
1960:
1959:
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1945:
1937:
1928:
1927:
1904:
1903:External links
1901:
1899:
1898:
1869:
1840:
1811:
1793:(5): 887–900.
1782:
1756:(12): 3713–5.
1745:
1700:
1657:
1629:(7): 1315–23.
1614:
1596:(2): 396–402.
1585:
1565:10.1038/nbt810
1548:
1505:
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671:dynein complex
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503:tail of embryo
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384:RNA expression
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2:
2115:
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2075:
2070:
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2063:
2062:
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2050:
2046:
2045:chromosome 20
2042:
2037:
2034:
2030:
2025:
2012:
2006:
2001:
1997:
1991:
1986:
1982:
1976:
1971:
1967:
1958:
1953:
1951:
1946:
1944:
1939:
1938:
1935:
1931:
1925:
1921:
1920:
1915:
1911:
1907:
1906:
1902:
1895:
1891:
1887:
1883:
1880:(3): 183–96.
1879:
1875:
1870:
1866:
1862:
1858:
1854:
1850:
1846:
1841:
1837:
1833:
1829:
1825:
1822:(3): 1125–9.
1821:
1817:
1812:
1808:
1804:
1800:
1796:
1792:
1788:
1783:
1779:
1775:
1771:
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1570:
1566:
1562:
1558:
1554:
1549:
1545:
1541:
1536:
1531:
1527:
1523:
1520:(5): 638–53.
1519:
1515:
1511:
1506:
1502:
1498:
1493:
1488:
1483:
1478:
1474:
1470:
1466:
1462:
1458:
1453:
1449:
1445:
1440:
1435:
1431:
1427:
1426:J. Biol. Chem
1423:
1418:
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1410:
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1371:
1367:
1362:
1357:
1353:
1349:
1345:
1341:
1337:
1332:
1331:
1326:
1317:
1311:
1309:
1305:
1300:
1296:
1291:
1286:
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1278:
1274:
1270:
1266:
1259:
1256:
1251:
1247:
1243:
1239:
1235:
1231:
1223:
1220:
1215:
1211:
1205:
1202:
1197:
1193:
1187:
1184:
1180:
1176:
1171:
1169:
1167:
1163:
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1155:
1150:
1148:
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1142:
1135:
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1131:
1127:
1123:
1119:
1114:
1112:
1109:
1105:
1101:
1089:
1084:
1080:
1076:
1073:
1069:
1062:
1060:
1057:
1053:
1049:
1045:
1042:
1038:
1034:
1027:
1025:
1021:
1015:
1011:
1008:
1002:
1000:
996:
992:
988:
984:
978:
974:
971:
967:
960:
958:
954:
948:
944:
941:
935:
933:
927:
923:
919:
915:
911:
907:
903:
900:
898:RefSeq (mRNA)
896:
889:
888:
883:
879:
876:
870:
869:
864:
860:
857:
855:
851:
844:
843:
838:
834:
831:
825:
824:
819:
815:
812:
810:
806:
799:
798:
793:
789:
786:
780:
779:
774:
770:
767:
765:
761:
758:
755:
753:
750:
746:
743:
739:
735:
728:
724:
719:
713:
710:
708:
705:
703:
700:
698:
695:
693:
690:
689:
687:
684:
683:
677:
674:
672:
669:
667:
664:
662:
659:
657:
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
628:
626:
623:
622:
616:
613:
611:
608:
606:
603:
601:
598:
597:
595:
592:
591:
588:
587:Gene ontology
584:
580:
568:
563:
560:
558:
554:
546:
541:
530:
526:
522:
518:
514:
510:
506:
502:
498:
494:
493:
490:
486:
481:
478:
468:
464:
460:
456:
452:
448:
444:
440:
436:
432:
431:
428:
424:
419:
416:
415:
412:
410:
406:
404:
403:
399:
398:
395:
393:
389:
385:
381:
377:
369:
364:
360:
356:
351:
341:
337:
330:
323:
317:
310:
302:
298:
294:
289:
285:
280:
276:
268:
263:
259:
255:
250:
240:
236:
229:
222:
216:
209:
205:
199:
195:
191:
186:
182:
177:
173:
169:
165:
161:
157:
153:
149:
145:
141:
137:
133:
125:
120:
113:
108:
103:
92:
90:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
16:
2053:expanding it
2038:
2023:
2010:
1995:
1980:
1929:
1917:
1877:
1873:
1851:(2): 173–4.
1848:
1844:
1819:
1815:
1790:
1787:J. Mol. Biol
1786:
1753:
1749:
1708:
1704:
1669:
1665:
1626:
1622:
1593:
1589:
1559:(5): 566–9.
1556:
1552:
1517:
1513:
1464:
1460:
1429:
1425:
1386:
1382:
1343:
1339:
1275:(3): 411–3.
1272:
1268:
1258:
1233:
1229:
1222:
1213:
1204:
1195:
1186:
1126:Upregulation
1115:
1107:
1099:
1098:
1020:NP_001278037
1017:
999:NP_001369296
995:NP_001369295
991:NP_001369294
983:NP_001306086
980:
953:NM_001291108
950:
932:NM_001319157
929:
914:NM_001281729
910:NM_001281728
906:NM_001281727
885:
866:
840:
821:
795:
776:
756:
751:
641:cytoskeleton
527:aortic valve
449:tibial nerve
407:
400:
366:155,092,197
353:155,078,453
127:External IDs
74:
15:
1963:PDB gallery
1269:J Cell Biol
1122:cytoplasmic
656:microtubule
636:ciliary tip
345:2|2 H1
265:34,540,958
252:34,516,409
105:Identifiers
2092:Categories
1666:Genome Res
1623:Genome Res
1340:Genome Res
1181:, May 2017
1160:, May 2017
1136:References
631:centrosome
453:C1 segment
411:(ortholog)
148:HomoloGene
2043:on human
1514:Genes Dev
1024:NP_080223
987:NP_054902
957:NM_025947
922:NM_177953
918:NM_014183
742:Orthologs
707:transport
651:cytoplasm
156:GeneCards
1894:18044744
1865:17556076
1836:16970917
1807:16950395
1778:24551435
1770:16778097
1733:16189514
1696:15489334
1653:15231747
1610:14733918
1581:23783563
1573:12665801
1544:12629046
1501:12477932
1448:12077152
1413:11780052
1370:11042152
1299:16260502
1250:11750132
1177:–
1156:–
1072:Wikidata
721:Sources:
646:membrane
515:yolk sac
244:20q11.22
1924:PDBe-KB
1914:UniProt
1741:4427026
1713:Bibcode
1469:Bibcode
1391:Bibcode
1290:2171247
1179:Ensembl
1158:Ensembl
1108:DYNLRB1
1104:protein
854:UniProt
809:Ensembl
748:Species
727:QuickGO
386:pattern
160:DYNLRB1
144:1914318
119:DYNLRB1
112:Aliases
24:DYNLRB1
1919:Q9NP97
1892:
1863:
1834:
1805:
1776:
1768:
1739:
1731:
1705:Nature
1694:
1687:528928
1684:
1651:
1644:442147
1641:
1608:
1579:
1571:
1542:
1535:196011
1532:
1499:
1492:139241
1489:
1446:
1411:
1383:Nature
1368:
1361:310934
1358:
1297:
1287:
1248:
1118:dynein
1058:search
1056:PubMed
887:P62627
868:Q9NP97
764:Entrez
661:cilium
557:BioGPS
136:607167
2047:is a
1774:S2CID
1737:S2CID
1577:S2CID
1102:is a
797:67068
778:83658
757:Mouse
752:Human
723:Amigo
409:Mouse
402:Human
349:Start
284:Mouse
248:Start
181:Human
152:69161
2049:stub
2041:gene
2011:2b95
1996:1z09
1981:1y4o
1912:for
1890:PMID
1861:PMID
1832:PMID
1803:PMID
1766:PMID
1729:PMID
1692:PMID
1649:PMID
1606:PMID
1569:PMID
1540:PMID
1497:PMID
1444:PMID
1409:PMID
1366:PMID
1295:PMID
1246:PMID
1230:Gene
1111:gene
392:Bgee
340:Band
301:Chr.
239:Band
198:Chr.
132:OMIM
89:2HZ5
85:2E8J
81:2B95
77:1Z09
58:RCSB
55:PDBe
1910:PDB
1882:doi
1853:doi
1849:175
1824:doi
1820:349
1795:doi
1791:362
1758:doi
1721:doi
1709:437
1682:PMC
1674:doi
1639:PMC
1631:doi
1598:doi
1594:314
1561:doi
1530:PMC
1522:doi
1487:PMC
1477:doi
1434:doi
1430:277
1399:doi
1387:414
1356:PMC
1348:doi
1285:PMC
1277:doi
1273:171
1238:doi
1234:281
565:n/a
362:End
261:End
164:OMA
140:MGI
48:PDB
2094::
1916::
1888:.
1878:65
1876:.
1859:.
1847:.
1830:.
1818:.
1801:.
1789:.
1772:.
1764:.
1754:12
1752:.
1735:.
1727:.
1719:.
1707:.
1690:.
1680:.
1670:14
1668:.
1664:.
1647:.
1637:.
1627:14
1625:.
1621:.
1604:.
1592:.
1575:.
1567:.
1557:21
1555:.
1538:.
1528:.
1518:17
1516:.
1512:.
1495:.
1485:.
1475:.
1465:99
1463:.
1459:.
1442:.
1428:.
1424:.
1407:.
1397:.
1385:.
1381:.
1364:.
1354:.
1344:10
1342:.
1338:.
1307:^
1293:.
1283:.
1271:.
1267:.
1244:.
1232:.
1212:.
1194:.
1165:^
1144:^
1113:.
725:/
368:bp
355:bp
267:bp
254:bp
162:;
158::
154:;
150::
146:;
142::
138:;
134::
87:,
83:,
79:,
2080:e
2073:t
2066:v
2055:.
1956:e
1949:t
1942:v
1926:.
1896:.
1884::
1867:.
1855::
1838:.
1826::
1809:.
1797::
1780:.
1760::
1743:.
1723::
1715::
1698:.
1676::
1655:.
1633::
1612:.
1600::
1583:.
1563::
1546:.
1524::
1503:.
1479::
1471::
1450:.
1436::
1415:.
1401::
1393::
1372:.
1350::
1318:.
1301:.
1279::
1252:.
1240::
1216:.
1198:.
286:)
183:)
166::
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