297:
274:
171:
196:
548:
303:
202:
2486:
50:
2226:
Tohda S, Murata-Ohsawa M, Sakano S, Nara N (2003). "Notch ligands, Delta-1 and Delta-4 suppress the self-renewal capacity and long-term growth of two myeloblastic leukemia cell lines".
2365:
2105:"The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway"
310:
209:
1369:
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during
1076:
1057:
132:
2465:
2310:"The Notch ligands, Jagged and Delta, are sequentially processed by alpha-secretase and presenilin/gamma-secretase and release signaling fragments"
1953:
Shimizu K, Chiba S, Saito T, Kumano K, Hirai H (2000). "Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors".
2555:
2531:
2358:
1466:
1448:
2550:
2027:"Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain"
296:
1503:"Manic fringe and lunatic fringe modify different sites of the Notch2 extracellular region, resulting in different signaling modulation"
1912:"Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2"
1593:"Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2"
1288:
1295:
273:
2183:"A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling"
1487:
2351:
1881:
Han W, Ye Q, Moore MA (2000). "A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells".
1752:
Gray GE, Mann RS, Mitsiadis E, Henrique D, Carcangiu ML, Banks A, Leiman J, Ward D, Ish-Horowitz D, Artavanis-Tsakonas S (1999).
1435:
1414:
1431:
195:
170:
47:
1410:
112:
1382:
309:
208:
1719:"Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation"
1676:"Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear"
2524:
302:
201:
1125:
120:
2386:
2378:
1106:
1102:
1591:
Shimizu K, Chiba S, Hosoya N, Kumano K, Saito T, Kurokawa M, Kanda Y, Hamada Y, Hirai H (September 2000).
2418:
2103:
Sakamoto K, Yamaguchi S, Ando R, Miyawaki A, Kabasawa Y, Takagi M, Li CL, Perbal B, Katsube K (2002).
2517:
2268:
184:
99:
2374:
1271:
1220:
1869:
1826:
1705:
1573:
144:
1910:
Shimizu K, Chiba S, Hosoya N, Kumano K, Saito T, Kurokawa M, Kanda Y, Hamada Y, Hirai H (2000).
1267:
1246:
1216:
1195:
547:
2331:
2296:
2243:
2214:
2169:
2140:"Delta-1 enhances marrow and thymus repopulating ability of human CD34+CD38β cord blood cells"
2126:
2091:
2056:
2013:
1984:"Differential Effects of Notch Ligands Delta-1 and Jagged-1 in Human Lymphoid Differentiation"
1970:
1941:
1898:
1894:
1861:
1818:
1783:
1740:
1697:
1662:
1622:
1565:
1524:
92:
40:
2501:
2343:
1982:
Jaleco AC, Neves H, Hooijberg E, Gameiro P, Clode N, Haury M, Henrique D, Parreira L (2001).
2321:
2286:
2276:
2235:
2204:
2194:
2159:
2151:
2116:
2081:
2046:
2038:
2003:
1995:
1962:
1931:
1923:
1890:
1851:
1808:
1773:
1765:
1730:
1687:
1654:
1612:
1604:
1555:
1514:
389:
320:
264:
219:
1544:"Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane"
364:
140:
2272:
2008:
1983:
1778:
1753:
2291:
2256:
2209:
2182:
2164:
2139:
2051:
2026:
1856:
1839:
1813:
1796:
1769:
1692:
1675:
1658:
1560:
1543:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
791:
786:
781:
776:
771:
766:
761:
756:
751:
746:
741:
736:
731:
726:
721:
716:
711:
706:
701:
696:
691:
686:
670:
665:
660:
655:
650:
645:
640:
635:
630:
625:
609:
604:
599:
594:
589:
2544:
2257:"The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and Ξ³-secretase"
1936:
1927:
1911:
1617:
1608:
1592:
1370:
576:
1873:
1830:
1577:
2497:
1709:
382:
161:
124:
148:
1797:"Expression of the mouse Delta1 gene during organogenesis and fetal development"
1645:
Watt FM (2002). "The stem cell compartment in human interfollicular epidermis".
1471:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1453:
National Center for
Biotechnology Information, U.S. National Library of Medicine
465:
103:, DELTA1, DL1, Delta, Delta-like 1, delta like canonical Notch ligand 1, NEDBAS
2025:
Shimizu K, Chiba S, Saito T, Takahashi T, Kumano K, Hamada Y, Hirai H (2002).
281:
178:
128:
2181:
KarlstrΓΆm H, Beatus P, Dannaeus K, Chapman G, Lendahl U, Lundkvist J (2003).
2042:
932:
Notch signaling pathway involved in arterial endothelial cell fate commitment
2281:
2255:
Six E, Ndiaye D, Laabi Y, Brou C, Gupta-Rossi N, Israel A, Logeat F (2003).
2070:"Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe"
1411:
ENSG00000198719 GRCh38: Ensembl release 89: ENSG00000275555, ENSG00000198719
1021:
525:
403:
348:
335:
247:
234:
136:
2335:
2326:
2309:
2300:
2247:
2218:
2199:
2173:
2130:
2121:
2104:
2095:
2086:
2069:
2060:
2017:
1974:
1966:
1945:
1902:
1865:
1822:
1787:
1735:
1718:
1666:
1626:
1528:
1519:
1502:
2239:
1999:
1744:
1701:
1569:
1335:
1330:
1501:
Shimizu K, Chiba S, Saito T, Kumano K, Takahashi T, Hirai H (July 2001).
1319:
1170:
1151:
2460:
2455:
2450:
2068:
Panin VM, Shao L, Lei L, Moloney DJ, Irvine KD, Haltiwanger RS (2002).
1838:
Morrison A, Hodgetts C, Gossler A, HrabΓ© de
Angelis M, Lewis J (1999).
1351:
1137:
1088:
742:
negative regulation of inner ear auditory receptor cell differentiation
69:
2155:
1386:
1303:
1043:
2485:
1840:"Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear"
1795:
Beckers J, Clark A, WΓΌnsch K, HrabΓ© De
Angelis M, Gossler A (1999).
1542:
Blaumueller CM, Qi H, Zagouras P, Artavanis-Tsakonas S (July 1997).
802:
regulation of vascular endothelial growth factor signaling pathway
1674:
Lewis AK, Frantz GD, Carpenter DA, de
Sauvage FJ, Gao WQ (1999).
1006:
1002:
2493:
2434:
2429:
2408:
2403:
1358:
556:
116:
2347:
982:
negative regulation of cardiac muscle cell differentiation
977:
positive regulation of transcription by RNA polymerase II
1717:
Mitsiadis TA, Hirsinger E, Lendahl U, Goridis C (1999).
372:
2505:
942:
negative regulation of epithelial cell differentiation
872:
cerebellar
Purkinje cell layer structural organization
852:
negative regulation of epidermal cell differentiation
537:
1373:. It may play a role in cell-to-cell communication.
972:
negative regulation of cell population proliferation
952:
positive regulation of skeletal muscle tissue growth
897:
positive regulation of cell population proliferation
2443:
2417:
2385:
1260:
1239:
1209:
1188:
947:
negative regulation of myeloid cell differentiation
757:
negative regulation of glial cell apoptotic process
1427:
1425:
1423:
1406:
1404:
1402:
319:
218:
2138:Ohishi K, Varnum-Finney B, Bernstein ID (2002).
697:negative regulation of interleukin-10 production
712:negative regulation of myoblast differentiation
1432:GRCm38: Ensembl release 89: ENSMUSG00000014773
967:positive regulation of Notch signaling pathway
2525:
2359:
1488:"Entrez Gene: DLL1 delta-like 1 (Drosophila)"
812:positive regulation of sprouting angiogenesis
732:negative regulation of neuron differentiation
8:
782:regulation of skeletal muscle tissue growth
762:negative regulation of cell differentiation
2532:
2518:
2366:
2352:
2344:
1017:
572:
360:
259:
156:
58:
2325:
2290:
2280:
2208:
2198:
2163:
2120:
2085:
2050:
2007:
1935:
1895:10.1182/blood.V95.5.1616.005k31_1616_1625
1855:
1812:
1777:
1734:
1691:
1616:
1559:
1518:
807:neuronal stem cell population maintenance
1482:
1480:
1398:
842:retina morphogenesis in camera-type eye
772:endothelial tip cell fate specification
882:positive regulation of gene expression
18:
1754:"Human Ligands of the Notch Receptor"
887:retina development in camera-type eye
646:integral component of plasma membrane
324:
285:
280:
223:
182:
177:
7:
2482:
2480:
862:determination of left/right symmetry
827:cerebellar molecular layer formation
787:marginal zone B cell differentiation
2504:. You can help Knowledge (XXG) by
1257:
1236:
1206:
1185:
1161:
1142:
1116:
1093:
1067:
1048:
937:type B pancreatic cell development
922:multicellular organism development
837:positive regulation of endocytosis
542:
460:
398:
377:
14:
1354:that in humans is encoded by the
877:compartment pattern specification
702:proximal/distal pattern formation
2484:
1928:10.1128/MCB.20.18.6913-6922.2000
1609:10.1128/mcb.20.18.6913-6922.2000
546:
308:
301:
295:
272:
207:
200:
194:
169:
1381:Delta-like 1 has been shown to
857:clathrin-dependent endocytosis
626:integral component of membrane
557:More reference expression data
526:More reference expression data
1:
2556:Human chromosome 6 gene stubs
2308:LaVoie MJ, Selkoe DJ (2003).
1955:Biochem. Biophys. Res. Commun
1857:10.1016/S0925-4773(99)00066-0
1814:10.1016/S0925-4773(99)00065-9
1770:10.1016/S0002-9440(10)65325-4
1693:10.1016/S0925-4773(98)00165-8
1659:10.1016/S0923-1811(02)00003-8
1561:10.1016/s0092-8674(00)80336-0
962:left/right axis specification
792:skeletal muscle tissue growth
293:
192:
2261:Proc. Natl. Acad. Sci. U.S.A
2187:Proc. Natl. Acad. Sci. U.S.A
817:regulation of blood pressure
2551:Genes on human chromosome 6
867:regulation of cell adhesion
847:proximal tubule development
727:regulation of cell division
722:regulation of somitogenesis
2572:
2479:
2444:Receptor on receiving cell
957:regulation of neurogenesis
892:skin epidermis development
508:medial ganglionic eminence
1467:"Mouse PubMed Reference:"
1449:"Human PubMed Reference:"
1334:
1329:
1325:
1318:
1302:
1289:Chr 6: 170.28 β 170.31 Mb
1283:
1264:
1243:
1232:
1213:
1192:
1181:
1168:
1164:
1149:
1145:
1136:
1123:
1119:
1100:
1096:
1087:
1074:
1070:
1055:
1051:
1042:
1027:
1020:
1016:
1000:
767:neuron fate specification
737:loop of Henle development
575:
571:
554:
545:
536:
523:
472:
463:
410:
401:
371:
363:
359:
342:
329:
292:
271:
262:
258:
241:
228:
191:
168:
159:
155:
110:
107:
97:
90:
85:
66:
61:
44:
39:
34:
30:
26:
21:
595:scaffold protein binding
2379:notch signaling pathway
2282:10.1073/pnas.1230693100
1296:Chr 17: 15.59 β 15.6 Mb
912:cell fate determination
907:spinal cord development
687:Notch signaling pathway
16:Protein found in humans
2327:10.1074/jbc.M302659200
2200:10.1073/pnas.252624099
2122:10.1074/jbc.M203727200
2087:10.1074/jbc.M204445200
2043:10.1093/emboj/21.3.294
1967:10.1006/bbrc.2000.3469
1736:10.1006/dbio.1998.9092
1520:10.1074/jbc.M103473200
661:apical plasma membrane
2240:10.3892/ijo.22.5.1073
2000:10.1084/jem.194.7.991
917:inner ear development
747:astrocyte development
450:minor salivary glands
326:17 A2|17 8.95 cM
287:Chromosome 17 (mouse)
1348:Delta-like protein 1
927:regulation of growth
752:somite specification
707:cell differentiation
651:extracellular region
185:Chromosome 6 (human)
62:List of PDB id codes
35:Available structures
2273:2003PNAS..100.7638S
902:nephron development
777:cell-cell signaling
671:cytoplasmic vesicle
600:Tat protein binding
590:calcium ion binding
504:ganglionic eminence
438:mucosa of esophagus
2492:This article on a
1126:ENSMUSG00000014773
992:energy homeostasis
832:cell communication
797:lateral inhibition
680:Biological process
619:Cellular component
583:Molecular function
2513:
2512:
2474:
2473:
2389:on signaling cell
2375:Signaling pathway
2115:(33): 29399β405.
1345:
1344:
1341:
1340:
1314:
1313:
1279:
1278:
1254:
1253:
1228:
1227:
1203:
1202:
1177:
1176:
1158:
1157:
1132:
1131:
1113:
1112:
1083:
1082:
1064:
1063:
1012:
1011:
636:adherens junction
567:
566:
563:
562:
532:
531:
519:
518:
476:paraxial mesoderm
457:
456:
355:
354:
254:
253:
81:
80:
77:
76:
45:Ortholog search:
2563:
2534:
2527:
2520:
2488:
2481:
2368:
2361:
2354:
2345:
2339:
2329:
2320:(36): 34427β37.
2304:
2294:
2284:
2251:
2222:
2212:
2202:
2193:(26): 17119β24.
2177:
2167:
2156:10.1172/JCI16167
2134:
2124:
2099:
2089:
2080:(33): 29945β52.
2064:
2054:
2021:
2011:
1978:
1949:
1939:
1906:
1877:
1859:
1834:
1816:
1791:
1781:
1748:
1738:
1713:
1695:
1670:
1647:J. Dermatol. Sci
1631:
1630:
1620:
1588:
1582:
1581:
1563:
1539:
1533:
1532:
1522:
1498:
1492:
1491:
1484:
1475:
1474:
1463:
1457:
1456:
1445:
1439:
1429:
1418:
1408:
1327:
1326:
1298:
1291:
1274:
1258:
1249:
1237:
1233:RefSeq (protein)
1223:
1207:
1198:
1186:
1162:
1143:
1117:
1094:
1068:
1049:
1018:
573:
559:
550:
543:
528:
488:primitive streak
484:ventricular zone
468:
466:Top expressed in
461:
418:ventricular zone
406:
404:Top expressed in
399:
378:
361:
351:
338:
327:
312:
305:
299:
288:
276:
260:
250:
237:
226:
211:
204:
198:
187:
173:
157:
151:
149:DLL1 - orthologs
102:
95:
72:
59:
53:
32:
31:
19:
2571:
2570:
2566:
2565:
2564:
2562:
2561:
2560:
2541:
2540:
2539:
2538:
2477:
2475:
2470:
2439:
2413:
2381:
2372:
2342:
2307:
2267:(13): 7638β43.
2254:
2225:
2180:
2144:J. Clin. Invest
2137:
2102:
2067:
2024:
1994:(7): 991β1002.
1981:
1952:
1922:(18): 6913β22.
1916:Mol. Cell. Biol
1909:
1880:
1850:(1β2): 169β72.
1837:
1794:
1751:
1716:
1686:(1β2): 159β63.
1673:
1644:
1640:
1638:Further reading
1635:
1634:
1603:(18): 6913β22.
1597:Mol. Cell. Biol
1590:
1589:
1585:
1541:
1540:
1536:
1513:(28): 25753β8.
1500:
1499:
1495:
1486:
1485:
1478:
1465:
1464:
1460:
1447:
1446:
1442:
1430:
1421:
1409:
1400:
1395:
1379:
1367:
1336:View/Edit Mouse
1331:View/Edit Human
1294:
1287:
1284:Location (UCSC)
1270:
1266:
1245:
1219:
1215:
1194:
1107:ENSG00000198719
1105:
1103:ENSG00000275555
996:
675:
641:plasma membrane
614:
610:protein binding
555:
524:
515:
510:
506:
502:
498:
494:
490:
486:
482:
478:
464:
453:
448:
444:
440:
436:
432:
428:
424:
422:skin of abdomen
420:
416:
402:
346:
333:
325:
315:
314:
313:
306:
286:
263:Gene location (
245:
232:
224:
214:
213:
212:
205:
183:
160:Gene location (
111:
98:
91:
68:
46:
17:
12:
11:
5:
2569:
2567:
2559:
2558:
2553:
2543:
2542:
2537:
2536:
2529:
2522:
2514:
2511:
2510:
2489:
2472:
2471:
2469:
2468:
2463:
2458:
2453:
2447:
2445:
2441:
2440:
2438:
2437:
2432:
2427:
2423:
2421:
2415:
2414:
2412:
2411:
2406:
2401:
2396:
2392:
2390:
2383:
2382:
2373:
2371:
2370:
2363:
2356:
2348:
2341:
2340:
2305:
2252:
2223:
2178:
2150:(8): 1165β74.
2135:
2100:
2065:
2037:(3): 294β302.
2022:
1979:
1950:
1907:
1889:(5): 1616β25.
1878:
1835:
1807:(1β2): 165β8.
1792:
1749:
1714:
1671:
1641:
1639:
1636:
1633:
1632:
1583:
1534:
1493:
1476:
1458:
1440:
1419:
1397:
1396:
1394:
1391:
1378:
1375:
1366:
1363:
1343:
1342:
1339:
1338:
1333:
1323:
1322:
1316:
1315:
1312:
1311:
1309:
1307:
1300:
1299:
1292:
1285:
1281:
1280:
1277:
1276:
1262:
1261:
1255:
1252:
1251:
1241:
1240:
1234:
1230:
1229:
1226:
1225:
1211:
1210:
1204:
1201:
1200:
1190:
1189:
1183:
1179:
1178:
1175:
1174:
1166:
1165:
1159:
1156:
1155:
1147:
1146:
1140:
1134:
1133:
1130:
1129:
1121:
1120:
1114:
1111:
1110:
1098:
1097:
1091:
1085:
1084:
1081:
1080:
1072:
1071:
1065:
1062:
1061:
1053:
1052:
1046:
1040:
1039:
1034:
1029:
1025:
1024:
1014:
1013:
1010:
1009:
998:
997:
995:
994:
989:
984:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
683:
681:
677:
676:
674:
673:
668:
663:
658:
653:
648:
643:
638:
633:
628:
622:
620:
616:
615:
613:
612:
607:
602:
597:
592:
586:
584:
580:
579:
569:
568:
565:
564:
561:
560:
552:
551:
540:
534:
533:
530:
529:
521:
520:
517:
516:
514:
513:
509:
505:
501:
500:corneal stroma
497:
493:
489:
485:
481:
480:tail of embryo
477:
473:
470:
469:
458:
455:
454:
452:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
411:
408:
407:
395:
394:
386:
375:
369:
368:
365:RNA expression
357:
356:
353:
352:
344:
340:
339:
331:
328:
323:
317:
316:
307:
300:
294:
290:
289:
284:
278:
277:
269:
268:
256:
255:
252:
251:
243:
239:
238:
230:
227:
222:
216:
215:
206:
199:
193:
189:
188:
181:
175:
174:
166:
165:
153:
152:
109:
105:
104:
96:
88:
87:
83:
82:
79:
78:
75:
74:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
2568:
2557:
2554:
2552:
2549:
2548:
2546:
2535:
2530:
2528:
2523:
2521:
2516:
2515:
2509:
2507:
2503:
2499:
2495:
2490:
2487:
2483:
2478:
2467:
2464:
2462:
2459:
2457:
2454:
2452:
2449:
2448:
2446:
2442:
2436:
2433:
2431:
2428:
2425:
2424:
2422:
2420:
2416:
2410:
2407:
2405:
2402:
2400:
2397:
2394:
2393:
2391:
2388:
2384:
2380:
2376:
2369:
2364:
2362:
2357:
2355:
2350:
2349:
2346:
2337:
2333:
2328:
2323:
2319:
2315:
2314:J. Biol. Chem
2311:
2306:
2302:
2298:
2293:
2288:
2283:
2278:
2274:
2270:
2266:
2262:
2258:
2253:
2249:
2245:
2241:
2237:
2234:(5): 1073β9.
2233:
2229:
2228:Int. J. Oncol
2224:
2220:
2216:
2211:
2206:
2201:
2196:
2192:
2188:
2184:
2179:
2175:
2171:
2166:
2161:
2157:
2153:
2149:
2145:
2141:
2136:
2132:
2128:
2123:
2118:
2114:
2110:
2109:J. Biol. Chem
2106:
2101:
2097:
2093:
2088:
2083:
2079:
2075:
2074:J. Biol. Chem
2071:
2066:
2062:
2058:
2053:
2048:
2044:
2040:
2036:
2032:
2028:
2023:
2019:
2015:
2010:
2005:
2001:
1997:
1993:
1989:
1985:
1980:
1976:
1972:
1968:
1964:
1960:
1956:
1951:
1947:
1943:
1938:
1933:
1929:
1925:
1921:
1917:
1913:
1908:
1904:
1900:
1896:
1892:
1888:
1884:
1879:
1875:
1871:
1867:
1863:
1858:
1853:
1849:
1845:
1841:
1836:
1832:
1828:
1824:
1820:
1815:
1810:
1806:
1802:
1798:
1793:
1789:
1785:
1780:
1775:
1771:
1767:
1764:(3): 785β94.
1763:
1759:
1758:Am. J. Pathol
1755:
1750:
1746:
1742:
1737:
1732:
1729:(2): 420β31.
1728:
1724:
1720:
1715:
1711:
1707:
1703:
1699:
1694:
1689:
1685:
1681:
1677:
1672:
1668:
1664:
1660:
1656:
1653:(3): 173β80.
1652:
1648:
1643:
1642:
1637:
1628:
1624:
1619:
1614:
1610:
1606:
1602:
1598:
1594:
1587:
1584:
1579:
1575:
1571:
1567:
1562:
1557:
1554:(2): 281β91.
1553:
1549:
1545:
1538:
1535:
1530:
1526:
1521:
1516:
1512:
1508:
1507:J. Biol. Chem
1504:
1497:
1494:
1489:
1483:
1481:
1477:
1472:
1468:
1462:
1459:
1454:
1450:
1444:
1441:
1437:
1433:
1428:
1426:
1424:
1420:
1416:
1412:
1407:
1405:
1403:
1399:
1392:
1390:
1388:
1384:
1376:
1374:
1372:
1371:hematopoiesis
1364:
1362:
1360:
1357:
1353:
1349:
1337:
1332:
1328:
1324:
1321:
1317:
1310:
1308:
1305:
1301:
1297:
1293:
1290:
1286:
1282:
1275:
1273:
1269:
1263:
1259:
1256:
1250:
1248:
1242:
1238:
1235:
1231:
1224:
1222:
1218:
1212:
1208:
1205:
1199:
1197:
1191:
1187:
1184:
1182:RefSeq (mRNA)
1180:
1173:
1172:
1167:
1163:
1160:
1154:
1153:
1148:
1144:
1141:
1139:
1135:
1128:
1127:
1122:
1118:
1115:
1109:
1108:
1104:
1099:
1095:
1092:
1090:
1086:
1079:
1078:
1073:
1069:
1066:
1060:
1059:
1054:
1050:
1047:
1045:
1041:
1038:
1035:
1033:
1030:
1026:
1023:
1019:
1015:
1008:
1004:
999:
993:
990:
988:
985:
983:
980:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
948:
945:
943:
940:
938:
935:
933:
930:
928:
925:
923:
920:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
822:heart looping
820:
818:
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
788:
785:
783:
780:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
753:
750:
748:
745:
743:
740:
738:
735:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
698:
695:
693:
692:somitogenesis
690:
688:
685:
684:
682:
679:
678:
672:
669:
667:
666:membrane raft
664:
662:
659:
657:
656:cell junction
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
623:
621:
618:
617:
611:
608:
606:
605:Notch binding
603:
601:
598:
596:
593:
591:
588:
587:
585:
582:
581:
578:
577:Gene ontology
574:
570:
558:
553:
549:
544:
541:
539:
535:
527:
522:
511:
507:
503:
499:
496:tongue muscle
495:
491:
487:
483:
479:
475:
474:
471:
467:
462:
459:
449:
446:right auricle
445:
441:
437:
434:apex of heart
433:
429:
425:
421:
417:
413:
412:
409:
405:
400:
397:
396:
393:
391:
387:
385:
384:
380:
379:
376:
374:
370:
366:
362:
358:
350:
345:
341:
337:
332:
322:
318:
311:
304:
298:
291:
283:
279:
275:
270:
266:
261:
257:
249:
244:
240:
236:
231:
221:
217:
210:
203:
197:
190:
186:
180:
176:
172:
167:
163:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
114:
106:
101:
94:
89:
84:
73:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
2506:expanding it
2498:chromosome 6
2491:
2476:
2398:
2317:
2313:
2264:
2260:
2231:
2227:
2190:
2186:
2147:
2143:
2112:
2108:
2077:
2073:
2034:
2030:
1991:
1987:
1961:(1): 385β9.
1958:
1954:
1919:
1915:
1886:
1882:
1847:
1843:
1804:
1800:
1761:
1757:
1726:
1722:
1683:
1679:
1650:
1646:
1600:
1596:
1586:
1551:
1547:
1537:
1510:
1506:
1496:
1470:
1461:
1452:
1443:
1380:
1377:Interactions
1368:
1355:
1347:
1346:
1272:NP_001365971
1265:
1244:
1221:NM_001379042
1214:
1193:
1169:
1150:
1124:
1101:
1075:
1056:
1036:
1031:
717:organ growth
492:ciliary body
388:
381:
246:170,306,565
233:170,282,206
108:External IDs
67:
1988:J. Exp. Med
987:hemopoiesis
426:skin of leg
347:15,597,134
334:15,587,616
86:Identifiers
2545:Categories
1438:, May 2017
1417:, May 2017
1393:References
512:right lung
392:(ortholog)
129:HomoloGene
2496:on human
1844:Mech. Dev
1801:Mech. Dev
1723:Dev. Biol
1680:Mech. Dev
1268:NP_031891
1247:NP_005609
1217:NM_007865
1196:NM_005618
1022:Orthologs
137:GeneCards
2387:Receptor
2336:12826675
2301:12794186
2248:12684674
2219:12482954
2174:12393852
2131:12050162
2096:12036964
2061:11823422
2018:11581320
1975:11006133
1946:10958687
1903:10688816
1874:17955906
1866:10473135
1831:15047523
1823:10473134
1788:10079256
1667:11912004
1627:10958687
1578:16544864
1529:11346656
1434:–
1413:–
1383:interact
1365:Function
1320:Wikidata
1001:Sources:
631:membrane
430:prostate
2466:Notch 4
2461:Notch 3
2456:Notch 2
2451:Notch 1
2269:Bibcode
2009:2193482
1779:1866435
1745:9882480
1710:9675950
1702:9858718
1570:9244302
1436:Ensembl
1415:Ensembl
1352:protein
1138:UniProt
1089:Ensembl
1028:Species
1007:QuickGO
367:pattern
93:Aliases
2426:Jagged
2419:Ligand
2334:
2299:
2292:164639
2289:
2246:
2217:
2210:139279
2207:
2172:
2165:150801
2162:
2129:
2094:
2059:
2052:125840
2049:
2031:EMBO J
2016:
2006:
1973:
1944:
1934:
1901:
1872:
1864:
1829:
1821:
1786:
1776:
1743:
1708:
1700:
1665:
1625:
1615:
1576:
1568:
1527:
1387:NOTCH2
1306:search
1304:PubMed
1171:Q61483
1152:O00548
1044:Entrez
538:BioGPS
442:vagina
414:spleen
125:104659
117:606582
2500:is a
2395:Delta
1937:88767
1883:Blood
1870:S2CID
1827:S2CID
1706:S2CID
1618:88767
1574:S2CID
1385:with
1350:is a
1077:13388
1058:28514
1037:Mouse
1032:Human
1003:Amigo
390:Mouse
383:Human
330:Start
265:Mouse
229:Start
162:Human
2502:stub
2494:gene
2435:JAG2
2430:JAG1
2409:DLL4
2404:DLL3
2399:DLL1
2332:PMID
2297:PMID
2244:PMID
2215:PMID
2170:PMID
2127:PMID
2092:PMID
2057:PMID
2014:PMID
1971:PMID
1942:PMID
1899:PMID
1862:PMID
1819:PMID
1784:PMID
1741:PMID
1698:PMID
1663:PMID
1623:PMID
1566:PMID
1548:Cell
1525:PMID
1359:gene
1356:DLL1
373:Bgee
321:Band
282:Chr.
225:6q27
220:Band
179:Chr.
141:DLL1
133:4104
113:OMIM
100:DLL1
70:4XBM
51:RCSB
48:PDBe
22:DLL1
2322:doi
2318:278
2287:PMC
2277:doi
2265:100
2236:doi
2205:PMC
2195:doi
2160:PMC
2152:doi
2148:110
2117:doi
2113:277
2082:doi
2078:277
2047:PMC
2039:doi
2004:PMC
1996:doi
1992:194
1963:doi
1959:276
1932:PMC
1924:doi
1891:doi
1852:doi
1809:doi
1774:PMC
1766:doi
1762:154
1731:doi
1727:204
1688:doi
1655:doi
1613:PMC
1605:doi
1556:doi
1515:doi
1511:276
343:End
242:End
145:OMA
121:MGI
41:PDB
2547::
2377::
2330:.
2316:.
2312:.
2295:.
2285:.
2275:.
2263:.
2259:.
2242:.
2232:22
2230:.
2213:.
2203:.
2191:99
2189:.
2185:.
2168:.
2158:.
2146:.
2142:.
2125:.
2111:.
2107:.
2090:.
2076:.
2072:.
2055:.
2045:.
2035:21
2033:.
2029:.
2012:.
2002:.
1990:.
1986:.
1969:.
1957:.
1940:.
1930:.
1920:20
1918:.
1914:.
1897:.
1887:95
1885:.
1868:.
1860:.
1848:84
1846:.
1842:.
1825:.
1817:.
1805:84
1803:.
1799:.
1782:.
1772:.
1760:.
1756:.
1739:.
1725:.
1721:.
1704:.
1696:.
1684:78
1682:.
1678:.
1661:.
1651:28
1649:.
1621:.
1611:.
1601:20
1599:.
1595:.
1572:.
1564:.
1552:90
1550:.
1546:.
1523:.
1509:.
1505:.
1479:^
1469:.
1451:.
1422:^
1401:^
1389:.
1361:.
1005:/
349:bp
336:bp
248:bp
235:bp
143:;
139::
135:;
131::
127:;
123::
119:;
115::
2533:e
2526:t
2519:v
2508:.
2367:e
2360:t
2353:v
2338:.
2324::
2303:.
2279::
2271::
2250:.
2238::
2221:.
2197::
2176:.
2154::
2133:.
2119::
2098:.
2084::
2063:.
2041::
2020:.
1998::
1977:.
1965::
1948:.
1926::
1905:.
1893::
1876:.
1854::
1833:.
1811::
1790:.
1768::
1747:.
1733::
1712:.
1690::
1669:.
1657::
1629:.
1607::
1580:.
1558::
1531:.
1517::
1490:.
1473:.
1455:.
267:)
164:)
147::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
