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Dennis S. Charney

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Feder, Adriana; Costi, Sara; Rutter, Sarah B.; Collins, Abigail B.; Govindarajulu, Usha; Jha, Manish K.; Horn, Sarah R.; Kautz, Marin; Corniquel, Morgan; Collins, Katherine A.; Bevilacqua, Laura (2021-02-01). "A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic
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research shows themes of randomized controlled trials and Esketamine. Traumatic stress is part of his psychology study and is frequently connected to suicide prevention, bridging the gap between various science disciplines and establishing new relationships. Other areas of study are bipolar disorder,
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Feder, Adriana; Parides, Michael K.; Murrough, James W.; Perez, Andrew M.; Morgan, Julia E.; Saxena, Shireen; Kirkwood, Katherine; Aan Het Rot, Marije; Lapidus, Kyle A. B.; Wan, Le-Ben; Iosifescu, Dan (2014). "Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a
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General psychiatry research includes work on anxiety, mood and psychopathology linked to work in injury prevention, thereby connecting myriad disciplines of study. Research into depression shows elements of internal medicine and management. Clinical psychology includes psychological intervention and
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insights into ketamine are a novel approach to the underlying operation of mechanism-of-action for rapid-acting antidepressant efficacy and mood disorders and is the first model of a rapid-acting antidepressant with efficacy for treatment-resistant symptoms of mood disorders. His intranasal ketamine
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Feder A, Costi S, Rutter SB, Collins AB, Govindarajulu U, Jha MK, Horn SR, Kautz M, Corniquel M, Collins KA, Bevilacqua L, Glasgow AM, Brallier J, Pietrzak RH, Murrough JW, Charney DS. A Randomized Controlled Trial of Repeated Ketamine Administration for Chronic Posttraumatic Stress Disorder.
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Krystal, John H.; Karper, Laurence P.; Seibyl, John P.; Freeman, Glenna K.; Delaney, Richard; Bremner, J. Douglas; Heninger, George R.; Bowers, Malcolm B. Jr; Charney, Dennis S. (1994-03-01). "Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans: Psychotomimetic,
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Goodman, Wayne K.; Price, Lawrence H.; Rasmussen, Steven A.; Mazure, Carolyn; Fleischmann, Roberta L.; Hill, Candy L.; Heninger, George R.; Charney, Dennis S. (1989-11-01). "The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability".
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Feder A, Parides MK, Murrough JW, Perez AM, Morgan JE, Saxena S, Kirkwood K, Aan Het Rot M, Lapidus KA, Wan LB, Iosifescu D, Charney DS. Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder: A Randomized Clinical Trial.
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Murrough JW, Iosifescu DV, Chang LC, Al Jurdi RK, Green CE, Perez AM, Iqbal S, Pillemer S, Foulkes A, Shah A, Charney DS, Mathew SJ. Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial.
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Iacoviello, Brian M.; Wu, Gang; Alvarez, Evan; Huryk, Kathryn; Collins, Katherine A.; Murrough, James W.; Iosifescu, Dan V.; Charney, Dennis S. (2014). "Cognitive-emotional training as an intervention for major depressive disorder".
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In 2007, he became the Dean of the School and Executive Vice President for Academic Affairs of what was then known as the Mount Sinai Medical Center. In 2013, he was named President of Academic Affairs for the
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Murrough, James W.; Iosifescu, Dan V.; Chang, Lee C.; Al Jurdi, Rayan K.; Green, Charles E.; Perez, Andrew M.; Iqbal, Syed; Pillemer, Sarah; Foulkes, Alexandra; Shah, Asim; Charney, Dennis S. (2013).
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Charney is the father of five children and grandfather of eight. On the morning of August 29, 2016, Charney was shot and wounded by Hengjun Chao, as Charney left Lange's Deli in Charney's hometown of
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Zarate CA Jr, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA, Charney DS, Manji HK. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.
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Feder, Adriana; Fred-Torres, Sharely; Southwick, Steven M.; Charney, Dennis S. (2019-09-15). "The Biology of Human Resilience: Opportunities for Enhancing Resilience Across the Life Span".
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Berman, R. M.; Cappiello, A.; Anand, A.; Oren, D. A.; Heninger, G. R.; Charney, D. S.; Krystal, J. H. (2000-02-15). "Antidepressant effects of ketamine in depressed patients".
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Charney, Alexander W.; Katz, Craig; Southwick, Steven M.; Charney, Dennis S. (2020-10-01). "A Call to Protect the Health Care Workers Fighting COVID-19 in the United States".
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Iacoviello BM, Wu G, Alvarez E, Huryk K, Collins KA, Murrough JW, Iosifescu DV, Charney DS. Cognitive-Emotional Training as an Intervention for Major Depressive Disorder.
171:, as well as the author of over 600 original papers and chapters. In 2022, he was listed #49 on Research.com's "Top Medicine Scientists in the United States," with an 572:. Chao's trial began on June 5, 2017, and eight days later Chao was convicted of attempted second-degree murder and two other charges in Westchester County Court in 576:. He was sentenced to 28 years in prison. These personal events contributed first-hand to his study of resilience and are discussed in this his book "Resilience". 2861: 435: 2019: 1984: 1924: 1841: 1973: 1576:, Charney, Dennis S. & Feder, Adriana, "Method for treating post-traumatic stress disorder", published 2019-11-19, assigned to 255:
Charney became the dean of research at Mount Sinai School of Medicine in 2004, later becoming the dean for academic and scientific affairs, then succeeding
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Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
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is effective for treating depression. Ketamine's use as a rapidly-acting anti-depressant is recognized as a breakthrough treatment in mental illness.
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2013 Charney DS, Nestler EJ, Buxbaum JD, Sklar Pamela (eds). Neurobiology of Mental Illness, New York, NY, Oxford University Press, Fourth Edition
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Feder A, Fred-Torres S, Southwick SM, Charney DS. The Biology of Human Resilience: Opportunities for Enhancing Resilience Across the Life Span.
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2011 Southwick SM, Litz BT, Charney DS, Friedman MJ Resilience and Mental Health: Challenges Across the Lifespan, Cambridge University Press
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Blake, Dudley David; Weathers, Frank W.; Nagy, Linda M.; Kaloupek, Danny G.; Gusman, Fred D.; Charney, Dennis S.; Keane, Terence M. (1995).
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Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS, Krystal JH: Antidepressant Effects of Ketamine in Depressed Patients.
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Charney DS: Psychobiological Mechanisms of resilience and vulnerability: Implications for the successful adaptation to extreme stress.
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Charney AW, Katz C, Southwick SM, Charney DS. A Call to Protect the Health Care Workers Fighting COVID-19 in the United States.
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2012 Charney DS, Southwick SM Resilience: The Science of Mastering Life's Greatest Challenges, Cambridge University Press
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He has been named among the top 3 most highly cited authors of psychiatric research in the decade ending in 2000 by the
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Charney, Dennis S; Babich, Karen S (2002). "Foundation for the NIMH strategic plan for mood disorders research".
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by American College of Neuropsychopharmacology and Joseph T. Coyle and Charles Nemeroff and Dennis Charney and
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Neurobiological and Clinical Consequences of Stress: From Normal Adaptation to Post-Traumatic Stress Disorder
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1999 The Gerald L. Klerman Lifetime Achievement Award from the Depression and Bipolar Support Alliance (DBSA)
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Insel, Thomas R.; Charney, Dennis S. (2003-06-18). "Research on Major DepressionStrategies and Priorities".
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Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB Jr, Charney DS.
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2017 Ketamine for Treatment-Resistant Depression – Named One of Top 10 on 2017 Health Care Innovations List
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Krystal, John H.; Abdallah, Chadi G.; Sanacora, Gerard; Charney, Dennis S.; Duman, Ronald S. (2019-03-06).
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by Gavin Andrews, Dennis S. Charney, Paul J. Sirovatka, Darrel A. Regier, American Psychiatric Publishing,
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published in 2018 that the development is the first new form of antidepressant since the 1950s.
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for resistant depression, Charney received the Donald Klein Lifetime Achievement Award from the
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https://www.science.org/content/article/global-health-institute-sued-age-and-sex-discrimination
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by Matthew J. Friedman, Dennis S. Charney, Ariel Y. Deutch, Lippincott Williams & Wilkins,
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of 218 with 173,960 citations across 887 publications. Charney is known for demonstrating that
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endocrinology and oncology. The endocrinology research is multidisciplinary, relying on the
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After losing suit against former boss at top med school, a scientist shoots him, police say
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According to published works, Charney's research is centered around various fields such as
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Video: Coping with Anxiety and Depression in Uncertain Times, National Library of Medicine
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In April 2019, a lawsuit was filed against Dr. Charney, several other defendants, and the
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2014 Distinguished Alumni Award from the Pennsylvania State University School of Medicine
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With Steven Southwick, MD, Professor of Psychiatry at Yale University, Charney authored
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2023 Donald Klein Lifetime Achievement Award, American Society for Psychopharmacology
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Charney, Dennis S; Nestler, Eric J; Sklar, Pamela; Buxbaum, Joseph D, eds. (2017).
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Stress-induced and Fear Circuitry Disorders: Refining the Research Agenda for Dsm-v
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Proceedings of the National Academy of Sciences of the United States of America
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The Yale-Brown Obsessive Compulsive Scale: I. Development, Use, and Reliability
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Blake DD, Weathers FW, Nagy LM, Kaloupek DG, Gusman FD, Charney DS, Keane TM.
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Biological Psychiatry: A Journal of Psychiatric Neuroscience and Therapeutics
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Researcher fired by Mount Sinai Medical Center sues for targeting, reputation
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1994–1995 Anna Monika Foundation Award for Research in Affective Disorders
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Video: Demons of Mind: Neuroscience and Other Weapons, Library of Congress
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1999 The American College of Psychiatrists Award for Depression Research
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2019 Colvin Prize for Outstanding Achievement in Mood Disorders Research
391:. In total, as of 2022, he holds nine issued patents and five pending. 172: 1951:"Med school dean recalls morning he was shot by researcher he'd fired" 784:, Dennis S. Charney, Lawrence Scahill, Andres Martin, Oxford Univ Pr, 2612:
Krystal, John H.; Charney, Dennis S.; Duman, Ronald S. (2020-04-02).
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Krystal JH, Charney DS, Duman RS. A New Rapid-Acting Antidepressant.
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2004 Research and Mood Disorders – American College of Psychiatrists
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2023 Rhoda & Bernard Sarnat International Prize in Mental Health
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Chao guilty of attempted murder in shooting of ex-boss in Chappaqua
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2014–2015 Distinguished Alumni Award, Pennsylvania State University
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2006 The Gold Medal Award from the Society of Biological Psychiatry
1288:"Ketamine: A Paradigm Shift for Depression Research and Treatment" 274:
and earlier was on the faculty in the department of psychiatry at
1160:"Resilience: The Science of Mastering Life's Greatest Challenges" 877:. J Trauma Stress. 1995 Jan;8(1):75-90. doi: 10.1007/BF02105408. 549:
1992 Daniel H. Efron Research Award from the American College of
2109:"Global health institute sued for age and sex discrimination," 2074:"Man Sentenced In Shooting Of Mount Sinai Medical School Dean," 2020:"Fired Professor Shot 2 Men Outside Chappaqua Deli, Police Say" 691:
Resilience: The Science of Mastering Life's Greatest Challenges
608:. He has been on the editorial board of 15 journals, including 215:
Resilience: The Science of Mastering Life's Greatest Challenges
2057:"Ex-researcher who shot dean found guilty of attempted murder" 456:
National Alliance for Research on Schizophrenia and Depression
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Fired Professor Shot 2 Men Outside Chappaqua Deli, Police Say
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2004 The American Psychiatric Association Award for Research
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The Physician's Guide to Depression & Bipolar Disorders
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Neuropsychopharmacology: The Fifth Generation of Progress
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Charney led the Mood and Anxiety Research Program at the
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The Physician's Guide to Depression and Bipolar Disorders
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was completed at the Connecticut Medical Health Center.
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Charney & Nestler's Neurobiology of Mental Illness,
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Dean's Office, Icahn School of Medicine at Mount Sinai
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Perceptual, Cognitive, and Neuroendocrine Responses".
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Charney & Nestler's Neurobiology of Mental Illness
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The development of a Clinician-Administered PTSD Scale
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Charney & Nestler's Neurobiology of Mental Illness
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Former chair, Board of Scientific Counselors for the
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in 1977 and completed his residency in Psychiatry at
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American Heart Association of New York Facebook Page
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Pediatric Psychoparmacology: Principles and Practice
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2004 CINP-Lilly Neuroscience Clinical Research Award
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2017 American Heart Association Heart of Gold Award
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Former scientific director, NIMH Strategic Plan for
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The Science of Mastering Life's Greatest Challenges
124: 109: 98: 83: 75: 67: 59: 45: 37: 21: 513:2014 The World's Most Influential Scientific Minds 227:, which went into its fifth edition in 2018. 2780:Icahn School of Medicine at Mount Sinai homepage 1456:Homayoun, Houman; Moghaddam, Bita (2008-11-18). 803:, Hardcover, Lippincott Williams & Wilkins, 751:by Dennis S. Charney, Lydia Lewis, McGraw-Hill, 129:https://icahn.mssm.edu/profiles/dennis-s-charney 2857:Icahn School of Medicine at Mount Sinai faculty 693:, Cambridge University Press, Second Edition, 434:Former chair, scientific advisory board of the 400:Principal investigator, VA National Center for 330:in 2019 and now produced under the brand name 1925:"American College of Neuropsychopharmacology" 1842:"American College of Neuropsychopharmacology" 8: 655:2023 Charney DS, Southwick DM, DePierro JM, 504:2017 - Fellow, National Academy of Inventors 408:Yale Mental Health Clinical Research Center. 2852:Members of the National Academy of Medicine 1731:"Past Outstanding Achievement Prizewinners" 1631:American College of Neuropsychopharmacology 858:Goodman WK, Price LH, Rasmussen SA, et al. 663:Cambridge University Press; Third Edition, 531:2000 Election, National Academy of Medicine 516:2009 ACNP Julius Axelrod Mentorship Award 210:and as of 2024 still holds these roles. 18: 2629: 2441: 2018:Bromwich, Jonah Engel (August 29, 2016). 1499: 1481: 1369:"In an Old Drug, New Hope for Depression" 1319: 454:Member, Scientific Advisory Board of the 240:Charney graduated from medical school at 1949:Bandler, Jonathan Bandler and Jonathan. 1735:Brain & Behavior Research Foundation 679:Oxford University Press; Fifth Edition, 460:Brain & Behavior Research Foundation 436:Anxiety Disorders Association of America 375:reuptake inhibitors in the treatment of 87:Election to National Academy of Medicine 1578:Icahn School of Medicine at Mount Sinai 1266:American Society for Clinical Pathology 994: 854:Charney's most cited publications are: 507:2015 The World's Most Influential Minds 443:Depression and Bipolar Support Alliance 308:American Society for Clinical Pathology 261:Icahn School of Medicine at Mount Sinai 196:Icahn School of Medicine at Mount Sinai 115:Icahn School of Medicine at Mount Sinai 2127:"Wisconsin Symposium on Human Biology" 1766:American Heart Association of New York 588:for sex and age discrimination at the 467:National Alliance for the Mentally Ill 2862:Penn State College of Medicine alumni 1877:The American College of Psychiatrists 1253: 1251: 537:1999 The Edward J. Sacher Award from 7: 2273:10.1001/archpsyc.1994.03950030035004 2190:10.1001/archpsyc.1989.01810110048007 1154: 1152: 1074: 1072: 1070: 1020: 1018: 1016: 606:Institute for Scientific Information 448:Past president, American College of 2614:"A New Rapid-Acting Antidepressant" 1436:"A New Rapid-Acting Antidepressant" 822:, Dennis S. Charney, Oxford Press, 764:Molecular Biology for the Clinician 590:Arnhold Institute for Global Health 430:National Institute of Mental Health 272:National Institute of Mental Health 169:Molecular Biology for the Clinician 2723:The American Journal of Psychiatry 2671:The American Journal of Psychiatry 2414:The American Journal of Psychiatry 2359:The American Journal of Psychiatry 1549:"Patent Abstract at Fresh Patents" 1196:10.1093/med/9780190681425.001.0001 1132:"Dean's Office - ISMMS Leadership" 14: 1524:"Patent Abstract at Patent Storm" 1231:"Trauma, Culture & the Brain" 63:Ketamine treatment for depression 2037:Guarino, Ben (August 31, 2016). 1866:Society of Biological Psychiatry 445:(DBSA) Scientific Advisory Board 29: 1889:"DBSA Gerald L. Klerman Awards" 689:2018 Charney DS, Southwick SM, 263:in 2007. He was elected to the 2867:Yale School of Medicine alumni 2735:10.1176/appi.ajp.2020.20050596 2683:10.1176/appi.ajp.2020.20040535 2575:10.1016/j.biopsych.2019.07.012 2480:10.1001/jamapsychiatry.2014.62 2426:10.1176/appi.ajp.2013.13030392 2261:Archives of General Psychiatry 2178:Archives of General Psychiatry 816:Neurobiology of Mental Illness 623:Journal of Affective Disorders 402:Post-traumatic Stress Disorder 326:treatment was approved by the 314:Ketamine treatment development 161:Neurobiology of Mental Illness 1: 2775:Mount Sinai Hospital homepage 2316:10.1016/s0006-3223(99)00230-9 1819:Penn State Alumni Association 1656:10.1016/S0006-3223(02)01543-3 1080:"Distinguished Alumni Awards" 1002:National Institutes of Health 675:2018 Charney DS, Nestler EJ, 635:Journal of Psychopharmacology 629:Acta Psychiatrica Scandinavia 2842:Bipolar disorder researchers 2827:American medical researchers 2466:randomized clinical trial". 1711:National Academy of Medicine 1304:10.1016/j.neuron.2019.02.005 617:Journal of Anxiety Disorders 413:Food and Drug Administration 194:and systems therapeutics at 2353:Charney, Dennis S. (2004). 2225:Journal of Traumatic Stress 1190:. Oxford University Press. 941:2013 Oct 1;170(10):1134-42. 644:Psychopharmacology Bulletin 16:American medical researcher 2888: 2822:American medical academics 2631:10.1016/j.cell.2020.02.033 2371:10.1176/appi.ajp.161.2.195 963:2019 Sep 15;86(6):443-453. 458:(NARSAD, now known as the 395:Affiliations and positions 2837:American textbook writers 1789:"Thomson Reuters Science" 985:2021 Feb 1;178(2).   956:. 2014 Aug;31(8):699-706. 586:Mount Sinai Health System 321:published that Charney's 300:major depressive disorder 208:Mount Sinai Health System 120: 91: 28: 1406:10.1001/jama.289.23.3167 1136:Icahn School of Medicine 904:Other notable articles: 640:Human Psychopharmacology 594:Icahn School of Medicine 367:Charney owns patents in 147:, with expertise in the 1830:Thomson Reuters Science 1600:EspaceNet Patent Search 1483:10.1073/pnas.0806669105 551:Neuropsychopharmacology 450:Neuropsychopharmacology 418:Drug Advisory Committee 246:Yale School of Medicine 141:biological psychiatrist 54:Yale School of Medicine 2832:American psychiatrists 2512:Depression and Anxiety 2237:10.1002/jts.2490080106 1913:Anna Monika Foundation 600:Books and publications 159:. He is the author of 2563:Biological Psychiatry 2304:Biological Psychiatry 1644:Biological Psychiatry 1087:Penn State University 949:2014 Jun;71(6):681-8. 910:Biological Psychiatry 611:Biological Psychiatry 423:Biological Psychiatry 421:Editorial committee, 265:Institute of Medicine 250:Biological Psychiatry 182:He is a professor of 103:Biological psychiatry 970:2020 Apr 2;181(1):7. 919:, 2004; 161:195-216. 236:Education and career 2043:The Washington Post 1596:"Biographical Data" 1474:2008PNAS..10518041H 1468:(46): 18041–18046. 1373:Scientific American 1050:"Dennis S. Charney" 924:Arch Gen Psychiatry 912:, 2000; 47:351-354. 900:. (4108 citations) 539:Columbia University 416:Psychopharmacologic 335:Scientific American 296:clinical psychology 276:Yale Medical School 219:Eric J. Nestler, MD 2805:2008-10-12 at the 2721:Stress Disorder". 2024:The New York Times 1755:Healthcare IT News 1112:patents.google.com 1007:2009-01-09 at the 885:. (6352 citations) 383:administration of 248:. A fellowship in 221:, he is author of 105:, research, author 2420:(10): 1134–1142. 2184:(11): 1006–1011. 1400:(23): 3167–3168. 1205:978-0-19-069885-0 772:978-1-58562-113-2 699:978-1-108-44166-7 685:978-0-19-068142-5 669:978-1-009-29974-9 481:Awards and honors 476:Research in 2002. 190:and professor of 157:anxiety disorders 151:and treatment of 137:Dennis S. Charney 134: 133: 93:Scientific career 23:Dennis S. Charney 2879: 2763: 2762: 2717: 2711: 2710: 2666: 2660: 2659: 2633: 2609: 2603: 2602: 2558: 2552: 2551: 2524:10.1002/da.22266 2506: 2500: 2499: 2462: 2456: 2455: 2445: 2405: 2399: 2398: 2350: 2344: 2343: 2299: 2293: 2292: 2255: 2249: 2248: 2216: 2210: 2209: 2172: 2166: 2165: 2163: 2162: 2148: 2142: 2141: 2139: 2138: 2129:. Archived from 2123: 2117: 2107: 2101: 2100: 2098: 2097: 2083: 2077: 2071: 2065: 2064: 2063:. 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Index


Penn State
Yale School of Medicine
Biological psychiatry
Icahn School of Medicine at Mount Sinai
https://icahn.mssm.edu/profiles/dennis-s-charney
biological psychiatrist
researcher
neurobiology
mood
anxiety disorders
h-index
ketamine
psychiatry
neuroscience
pharmacology
Icahn School of Medicine at Mount Sinai
New York City
Mount Sinai Health System
Eric J. Nestler, MD
Penn State
Yale School of Medicine
Biological Psychiatry
Kenneth L. Davis
Icahn School of Medicine at Mount Sinai
Institute of Medicine
National Institute of Mental Health
Yale Medical School
psychiatry
anesthesia

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