359:
336:
49:
40:
710:
Mulugeta W, Wilkes J, Mulatu W, Majiwa PA, Masake R, Peregrine AS (April 1997). "Long-term occurrence of
Trypanosoma congolense resistant to diminazene, isometamidium and homidium in cattle at Ghibe, Ethiopia".
97:
422:
573:(low blood pressure). Diminazen can harm the liver, kidneys and brain, which is potentially life-threatening; camels are especially susceptible to these effects.
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showed universal resistance between July 1989 and
February 1993. This likely indicates a permanent loss of function in this area against the tested target,
483:
456:
151:
127:
769:
244:
315:
540:
774:
464:
InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20)
658:"Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali"
86:
79:
354:
591:
90:
304:
656:
Mungube EO, Vitouley HS, Allegye-Cudjoe E, Diall O, Boucoum Z, Diarra B, et al. (August 2012).
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for animals that is sold under a variety of brand names. It is effective against certain
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634:
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Peregrine AS, Mamman M (September 1993). "Pharmacology of diminazene: a review".
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The mechanism is not well understood; it probably inhibits
705:
703:
74:
4,4'-(1-Triazene-1,3-diyl)bis(benzenecarboximidamide)
569:Acute side effects include vomiting, diarrhea, and
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516:. The drug may also be effective against certain
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444:C1=CC(=CC=C1C(=N)N)N/N=N/C2=CC=C(C=C2)C(=N)N
30:
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27:Anti-parasite drug with a di-amidine
203:
66:Azidin, Berenil, Ganasag, Pirocide
25:
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47:
38:
469:Key:XNYZHCFCZNMTFY-UHFFFAOYSA-N
376:
1:
729:10.1016/s0001-706x(96)00645-6
635:10.1016/0001-706X(93)90092-P
557:, but also has affinity to
796:
366:Chemical and physical data
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147:
46:
37:
550:, diminazene aceturate.
159:4-benzenecarboximidamide
675:10.1186/1756-3305-5-155
662:Parasites & Vectors
490:) is an anti-infective
535:Chemically it is a di-
770:Antiprotozoal agents
585:Valley in southwest
18:Diminazene aceturate
135:Veterinary use only
34:
477:
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423:Interactive image
316:CompTox Dashboard
16:(Redirected from
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775:Veterinary drugs
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629:(3–4): 185–203.
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486:; also known as
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555:DNA replication
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592:T. congolense
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529:Streptococcus
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349:ECHA InfoCard
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713:Acta Tropica
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623:Acta Tropica
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597:Boran cattle
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565:Side effects
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305:ChEMBL124025
128:Legal status
122:Legal status
571:hypotension
507:Trypanosoma
406: g·mol
355:100.007.860
285:CHEBI:81724
143:Identifiers
98:ATCvet code
71:Other names
62:Trade names
759:Categories
603:References
583:Gibe River
577:Resistance
541:formulated
539:and it is
520:including
513:Cytauxzoon
492:medication
480:Diminazene
411:3D model (
399:Molar mass
265:JI8SAD85NO
254:Y5G36EEA5Z
225:ChemSpider
169:CAS Number
152:IUPAC name
32:Diminazene
780:Triazenes
545:aceturate
488:diminazen
260:aceturate
184:aceturate
80:Routes of
765:Amidines
745:23878484
721:Elsevier
694:22852796
587:Ethiopia
523:Brucella
518:bacteria
498:such as
496:protozoa
189:908-54-3
178:536-71-0
106:QP51DF01
737:9107367
719:(3–4).
685:3432589
668:: 155.
643:7902657
543:as its
537:amidine
501:Babesia
404:281.323
372:Formula
262::
200:PubChem
186::
114:)
108: (
743:
735:
692:
682:
641:
510:, and
437:SMILES
296:ChEMBL
741:S2CID
457:InChI
413:JSmol
276:ChEBI
733:PMID
690:PMID
639:PMID
581:The
548:salt
526:and
245:UNII
234:2264
214:2354
725:doi
680:PMC
670:doi
631:doi
559:RNA
484:INN
321:EPA
204:CID
111:WHO
761::
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717:64
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702:^
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91:SC
89:,
87:IM
747:.
727::
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672::
666:5
645:.
633::
482:(
415:)
392:7
389:N
383:H
377:C
323:)
319:(
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
