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Dithizone is used to assess the purity of human pancreatic islet preparations used for transplantation into patients with type 1 diabetes. Dithizone binds zinc ions present in the islet's beta cells, and therefore stains the islets red. Exocrine tissue also present in the preparations does not bind
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Bendl BJ (1969) Thallium poisoning: report of a case successfully treated with dithizone. Arch
Dermatol 100:443–446 URL=
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Ricordi, C; Gray, DW; Hering, BJ; Kaufman, DB; Warnock, GL; Kneteman, NM; Lake, SP; London, NJ; et al. (1990).
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InChI=1S/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+
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InChI=1/C13H12N4S/c18-13(16-14-11-7-3-1-4-8-11)17-15-12-9-5-2-6-10-12/h1-10,14H,(H,16,18)/b17-15+
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https://jamanetwork.com/journals/jamadermatology/article-abstract/531202
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Except where otherwise noted, data are given for materials in their
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Diphenylthiocarbazone, 1,5-Diphenylthiocarbazone
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is a sulfur-containing organic compound. It is a good
522:"Islet isolation assessment in man and large animals"
405:, and forms complexes with many toxic metals such as
492:John H. Billman and Elizabeth S. Cleland (1955).
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436:dithizone, and is therefore not stained.
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420:Dithizone may be prepared by reacting
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247:Key: UOFGSWVZMUXXIY-BMRADRMJSA-N
49:(1E)-3-anilino-1-phenylimino-thiourea
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257:Key: UOFGSWVZMUXXIY-BMRADRMJBA
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360:(at 25 °C , 100 kPa).
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278:S=C(/N=N/c1ccccc1)NNc2ccccc2
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508:, vol. 3, p. 360
529:Acta Diabetologica Latina
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462:Dithizone in Ethanol 96%
568:Thiocarbonyl compounds
430:potassium hydroxide
332: g·mol
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541:10.1007/BF02581331
387:Infobox references
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506:Collected Volumes
499:Organic Syntheses
395:Chemical compound
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343:Safety data sheet
200:CompTox Dashboard
104:Interactive image
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63:Identifiers
55:Other names
494:"Dithizone"
287:Properties
142:100.000.413
468:References
325:Molar mass
188:NJZ2CJ4D6P
115:ChemSpider
91:3D model (
70:CAS Number
46:IUPAC name
17:Dithizone
450:Dithizone
399:Dithizone
562:Category
411:thallium
337:Hazards
549:2075782
415:mercury
380:what is
378: (
155:PubChem
80:60-10-6
547:
403:ligand
375:verify
372:
345:(SDS)
330:256.33
271:SMILES
168:657262
124:571406
40:Names
525:(PDF)
424:with
236:InChI
93:JSmol
545:PMID
413:and
407:lead
179:UNII
537:doi
205:EPA
158:CID
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533:27
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409:,
309:12
303:13
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370:Y
318:S
315:4
312:N
306:H
300:C
207:)
203:(
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