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InChI=1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1
29:
38:
652:
Doramectin is available for horses as an oral, flavored, bioadhesive gel under the name
Doraquest L.A. Oral Gel. It can be used to control and treat internal parasites as roundworms, lungworms and some external parasites.
572:
It is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites). Doramectin is a derivative of
274:)-6-cyclohexyl-21',24'-dihydroxy-12'-{oxy}-4-methoxy-6-methyloxan-2-yl]oxy}-5,11',13',22'-tetramethyl-5,6-dihydro-3',7',19'-trioxaspiropentacosane]-10',14',16',22'-tetraen-2'-one
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Goudie AC, Evans NA, Gration KA, Bishop BF, Gibson SP, Holdom KS, et al. (July 1993). "Doramectin--a potent novel endectocide".
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576:. Similarly to other drugs of this family, it is produced by fermentation by selected strains of
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Doramectin is marketed in other countries as
Doramec L.A. for cattle, sheep, and swine.
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628:, among many other internal and external parasites. It is available as an
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537:(FDA) for the treatment of parasites such as gastrointestinal
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25-cyclohexyl-5-O-demethyl-25-de(l-methylpropyl)avermectin A1a
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393:
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followed by chemical modification. Its spectrum includes:
740:"FDA Approves First Generic Doramectin for Use in Cattle"
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69:25-cyclohexyl-25-de(l-methylpropyl)avermectin B1a,
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678:"Dectomax- doramectin injection, solution"
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565:. It is available as a combination with
711:"Dectomax Pour-On- doramectin solution"
662:
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18:
89:
7:
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14:
1278:Glutamate-gated chloride channel
561:in cattle. It is available as a
455:
36:
27:
500:Key:QLFZZSKTJWDQOS-YDBLARSUSA-N
461:
449:
1:
569:under the brand name Valcor.
808:10.1016/0304-4017(93)90218-c
746:Food and Drug Administration
535:Food and Drug Administration
525:, sold under the brand name
66:25-cyclohexylavermectin B1,
1604:
1316:+esafoxolaner/praziquantel
1132:+esafoxolaner/eprinomectin
983:+esafoxolaner/eprinomectin
439:Chemical and physical data
1533:
882:Antiplatyhelmintic agents
508:
483:
210:
35:
26:
774:animaldrugsatfda.fda.gov
579:Streptomyces avermitilis
91:International Drug Names
796:Veterinary Parasitology
609:Dictyocaulus viviparus
531:veterinary medication
1488:naphthalenesulfonate
1372:tetrahydropyrimidine
1209:Antinematodal agents
770:"Animal Drugs @ FDA"
1521:Tetrachloroethylene
684:. 13 September 2022
640:Society and culture
619:Boophilus microplus
533:approved by the US
529:among others, is a
23:
1560:Never to phase III
1438:Diethylcarbamazine
615:Dermatobia hominis
563:generic medication
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750:. 11 January 2023
520:
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389:CompTox Dashboard
198: for animals
193:
110:
16:Chemical compound
1595:
1588:Veterinary drugs
1383:pyrantel pamoate
1351:Milbemycin oxime
1221:
1215:macrofilaricides
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896:schistosomicides
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55:Dectomax, others
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1506:Hexylresorcinol
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943:phosphonic acid
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922:Triclabendazole
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891:Antitrematodals
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717:. 5 August 2022
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625:Psoroptes bovis
603:Oesophagostomum
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1474:benzylammonium
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1261:Ciclobendazole
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1235:benzimidazole
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1190:
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1114:Other/unknown
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1098:
1097:benzimidazole
1094:
1093:
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1089:
1084:
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1072:Anticestodals
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1056:Tartar emetic
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960:Other/unknown
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916:benzimidazole
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861:Anthelmintics
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469:
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429:
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422:ECHA InfoCard
418:
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405:DTXSID9048982
402:
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140:intramuscular
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45:Clinical data
43:
39:
34:
30:
25:
1486:
1472:
1458:
1444:
1427:
1370:
1333:
1312:Eprinomectin
1301:
1289:
1266:Flubendazole
1256:Fenbendazole
1251:Tiabendazole
1233:
1189:Dichlorophen
1183:chlorophenol
1181:
1167:
1153:
1139:
1128:Praziquantel
1120:
1095:
1042:
1025:thioxanthone
1023:
1009:
995:
979:Praziquantel
966:
941:
914:
869:endectocides
799:
795:
789:
777:. Retrieved
773:
764:
752:. Retrieved
743:
719:. Retrieved
714:
686:. Retrieved
681:
651:
648:
623:
613:
607:
606:species and
601:
583:
577:
571:
555:sucking lice
526:
522:
521:
510:
271:
267:
263:
259:
255:
251:
247:
243:
239:
235:
231:
227:
223:
181:Legal status
175:Legal status
136:Subcutaneous
99:License data
1546:from market
1460:quinolinium
1345:+fluralaner
1335:milbemycins
1291:avermectins
1246:Albendazole
1241:Mebendazole
1147:Niclosamide
1103:Albendazole
1077:taeniacides
989:Oxamniquine
949:Metrifonate
802:(1): 5–15.
645:Brand names
559:mange mites
479: g·mol
428:100.123.125
293:117704-25-3
206:Identifiers
151:ATCvet code
60:Other names
51:Trade names
1577:Categories
1501:Ascaridole
1452:Levamisole
1433:Piperazine
1428:piperazine
1341:Moxidectin
1327:Selamectin
1322:Ivermectin
1302:Doramectin
1212:(including
1175:Desaspidin
1161:Quinacrine
1036:Lucanthone
1031:Hycanthone
1017:Niridazole
779:25 January
754:25 January
721:25 January
688:25 January
657:References
636:solution.
589:Ostertagia
585:Haemonchus
574:avermectin
567:levamisole
539:roundworms
523:Doramectin
472:Molar mass
358:KGD7A54H5P
329:ChemSpider
284:CAS Number
215:IUPAC name
118:Doramectin
21:Doramectin
1556:Phase III
1544:Withdrawn
1480:Bephenium
1466:Pyrvinium
1409:felsantel
1400:Carbantel
1307:Emamectin
1297:Abamectin
1122:quinoline
1051:Stibophen
1046:compounds
1003:Bithionol
968:quinoline
632:and as a
630:injection
543:lungworms
129:Routes of
85:Drugs.com
1511:Santonin
1446:thiazole
1405:Febantel
1395:Morantel
1378:Pyrantel
1044:antimony
1011:thiazole
859: –
715:DailyMed
682:DailyMed
597:Cooperia
547:eyeworms
527:Dectomax
513:(verify)
159:QP54AA03
113:DailyMed
1494:Suramin
1390:Oxantel
1226:tubulin
1088:tubulin
907:tubulin
816:8236738
634:topical
477:899.128
445:Formula
338:8008478
318:9832750
304:PubChem
167:)
161: (
144:topical
115::
1539:WHO-EM
1224:Binds
1086:Binds
997:phenol
905:Binds
867:) and
814:
622:, and
600:, and
557:, and
378:D01129
194:
111:
1407:(aka
748:(FDA)
744:U.S.
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