Knowledge (XXG)

Ethiofencarb

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342: 249: 563: 568: 85: 22: 72: 701:-methyl group undergoes hydroxylation. Sulfur is rapidly oxidized to give ethiofencarb sulfoxide. As stated above, ethiofencarb is stable in acidic conditions, but hydrolyzes when in the presence of a base. It was found to rapidly hydrolyze at pH conditions of 9 and 12. When subjected to sunlight, the main products that resulted from photodegredation are 723:
In humans, ethiofencarb can cause muscle weakness, dizziness, flushness, excess salivation, nausea, vomiting, diarrhea, abdominal pain, blurred vision, slurred speech and twitching. If a very high dose of ethiofencarb is administered then seizures, comas or hypertension could result. In severe cases,
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and 3-methylbenzooxazine-2-4-dione. The main reaction to occur is the precession of ethiofencarb to its sulfide. When in plants, ethiofencarb is close to optimum lipophilicity as the plant breathes. The chemical is metabolized to a sulfoxide, to a sulfone and then hydrolyzed to a phenol sulfoxide and
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There have been a few human deaths reported. In one case, a 56-year-old gardener who had come in contact with too much of the insecticide, was found unconscious in his car after vomiting and was taken to a hospital. He developed a severe case of pulmonary edema within an hour of admission, and after
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Ethiofencarb has an atmospheric half-life of 16 hours. When exposed to soil, ethiofencarb is moderately mobile and remains within the ground. It has been found to have a half-life of 2 weeks under greenhouse conditions. When added to water, it typically does not associate with the sediment, and can
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Carbamates are effective insecticides because of their ability to inhibit acetylcholinesterase (AChE) in the nervous system. Carbamate pesticides are less dangerous to humans than organophosphorus pesticides because carbamylation of the enzyme is unstable, and the regeneration of AChE is faster
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Rats were administered a dosage of ethiofencarb, which was radio labeled, for 10 days and their urine was analyzed. It was found that 95% of the radioactivity was urinated out within 72 hours of administration. This chemical is rapidly oxidized in the bodies of mammals, hydrolyzing to phenolic
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remain unchanged in an acidic environment, while it is hydrolyzed in an alkaline one. When dissolved in water, ethiofencarb is readily photodegraded by sunlight. Ethiofencarb could be transported from place to place in the environment through various natural waste pathways.
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Carbamic acid, methyl-, 2-(ethylthiomethyl)phenyl ester , Croneton , Ethiofencarb , Ethiofencarb , ethiophencarbe , Ethiophencarp , HOX 1901 , Phenol, 2-?(ethylthio)methyl-, methylcarbamate , Phenol, 2-(ethylthio)methyl , Phenol, 2-(ethylthio)methyl-, methylcarbamate (9CI),
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which is useful in controlling aphids on hard and soft fruits and some vegetables. It is not as dangerous as organophosphorous pesticides, but is considered highly toxic to humans in the UK, moderately toxic under US EPA classification, and highly toxic to aquatic life.
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compared to a phosphorylated enzyme. Therefore the dose required to produce minimum symptoms of poisoning and a lethal dose is substantially larger for carbamate compounds than for organophosphorus compounds.
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as a 'highly hazardous' pesticide and the European Union's Nordic Council of Ministers refers to it as 'dangerous to the environment'. This chemical is no longer used or produced within the United States.
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three hours, he died and 26.4 mg/L ethiofencarb, along with 0/12 g/100 mL ethanol, 37.9 mg/L ethiofencarbsulfoxide and 0.9 mg/L ethiofencarbsulfone were found in his urine analysis.
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Carbamic acid, methyl-, 2-(ethylthiomethyl)phenyl ester , Croneton , Ethiofencarb , Ethiofencarb , ethiophencarbe , Ethiophencarp , HOX 1901 , Phenol, 2-(ethylthio)methyl
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Al-Samarraie, MS; Karinen, R; Rognum, T; Hasvold, I; Opdal Stokke, M; Christophersen, AS (2009). "Lethal poisoning with ethiofencarb and ethanol".
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dyspnea, bronchospasms and bronchorrhea with impending pulmonary edema have been known to occur.
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InChI=1/C11H15NO2S/c1-3-15-8-9-6-4-5-7-10(9)14-11(13)12-2/h4-7H,3,8H2,1-2H3,(H,12,13)/f/h12H
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Kalyani Paranjape; Vasant Gowariker; V N Krishnamurthy; Sugha Gowariker (22 December 2014).
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by adding information on neglected viewpoints, or discuss the issue on the
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Metabolic Pathways of Agrochemicals: Part 2: Insecticides and Fungicides
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Except where otherwise noted, data are given for materials in their
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In dichloromethane, isopropanol and toluene >200, hexane 5-10
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Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)
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2-Ethoxycarbonyl-1-methylvinyl cyclohexyl methylphosphonate
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Carbamate groups are hydrolyzed to produce phenols and the
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RSC Publishing. pp. 40–44. 14: 1088:Tooltip Choline acetyltransferase 2148:Fasciculins (green mamba toxins) 1639:Dicyclohexyl phosphorofluoridate 987:Journal of Analytical Toxicology 882:"ethiofencarb (Ref: BAY 108594)" 566: 561: 419: 413: 83: 70: 20: 2733:Acetylcholinesterase inhibitors 2079:Tetraethyl pyrophosphate (TEPP) 1804:Hexaethyl tetraphosphate (HETP) 911:PubChem Open Chemistry Database 650:(at 25 °C , 100 kPa). 1149:N,N-Dimethylaminoethylacrylate 525:Occupational safety and health 428: 422: 407: 77:Line structure of ethiofencarb 1: 2702:Receptor/signaling modulators 2474:Hemicholinium-3 (hemicholine) 2373:Tooltip Butyrylcholinesterase 736:Ethiofencarb is known to the 481:Decomposes upon distillation 2748:Peripherally selective drugs 1169:Tooltip Acetylcholinesterase 2463:Tooltip Choline transporter 2409:Profenamine (ethopropazine) 1649:Diisopropyl fluorophosphate 1114:4-(1-Naphthylvinyl)pyridine 1099:1-(-Benzoylethyl)pyridinium 2769: 2312:Dimethylcarbamoyl fluoride 1119:Acetylseco hemicholinium-3 857:The Pesticide Encyclopedia 2694: 934:Roberts, Terence (1999). 738:World Health Organization 644: 542: 522: 517: 394: 374: 352: 125: 112: 100: 95: 82: 69: 35:toward certain viewpoints 2182:Methanesulfonyl fluoride 609:Precautionary statements 106:2-phenyl methylcarbamate 1359:+glycopyrronium bromide 860:. CABI. pp. 187–. 120:-tolyl methylcarbamate 2738:Carbamate insecticides 1109:3-Chloro-4-stillbazole 781:. PPDB. Archived from 703:2-hydroxybenzaldehyde 2670:Atracotoxins (e.g., 2297:Tetrahydrocannabinol 1644:Diisopropylphosphate 999:10.1093/jat/33.7.389 451:Colorless crystals 386:O=C(Oc1ccccc1CSCC)NC 102:Preferred IUPAC name 2753:Aromatic carbamates 2656:Tooltip Latrophilin 2358:Trimedoxime bromide 2287:Stercuronium iodide 2104:Tricresyl phosphate 1579:Chlorpyrifos-methyl 680:Mechanism of action 538:Toxic if swallowed 488:Solubility in water 461:1.231 g/cm (20 °C) 443: g·mol 66: 41:improve the article 2175:Onchidella binneyi 1517:Organophosphates: 706:a phenol sulfone. 689:Environmental fate 654:Infobox references 493:1.82 g/L at 20°C 64: 2720: 2719: 2690: 2689: 2538: 2523: 2522: 2450: 2435: 2434: 2074:Tetrachlorvinphos 1949:Pirimiphos-methyl 1899:Oxydemeton-methyl 1849:Methyl phenkapton 1075: 867:978-1-78064-014-3 662:Chemical compound 660: 659: 591:Hazard statements 321:CompTox Dashboard 167:Interactive image 62: 61: 2760: 2657: 2653: 2592: 2588: 2561: 2557: 2542: 2532: 2505: 2501: 2464: 2460: 2454: 2444: 2374: 2370: 2338:Asoxime chloride 1914:Parathion-methyl 1614:Demeton-S-methyl 1170: 1166: 1089: 1085: 1079: 1069: 1041: 1034: 1027: 1018: 1011: 1010: 982: 976: 975: 973: 972: 961: 952: 951: 931: 922: 921: 919: 917: 903: 897: 896: 894: 892: 878: 872: 871: 851: 845: 844: 842: 841: 830: 824: 815: 794: 793: 791: 790: 775: 766: 765: 758: 640: 636: 632: 628: 624: 620: 616: 602: 598: 570: 565: 442: 430: 424: 421: 415: 409: 402:Chemical formula 345: 344: 329: 327: 311: 291: 280: 259: 251: 240: 229: 209: 189: 169: 145: 87: 74: 67: 57: 54: 48: 24: 23: 16: 2768: 2767: 2763: 2762: 2761: 2759: 2758: 2757: 2723: 2722: 2721: 2716: 2686: 2655: 2636: 2596:Botulinum toxin 2590: 2565:Botulinum toxin 2559: 2531: 2519: 2503: 2493: 2479:Triethylcholine 2462: 2443: 2431: 2372: 2362: 2282:Rosmarinic acid 2049:Sulfotep (TEDP) 1719:Ethylsarin (GE) 1599:Cyclosarin (GF) 1569:Chlorfenvinphos 1559:Carbophenothion 1539:Azinphos-methyl 1168: 1158: 1124:Acryloylcholine 1087: 1068: 1060: 1045: 1015: 1014: 984: 983: 979: 970: 968: 963: 962: 955: 948: 933: 932: 925: 915: 913: 905: 904: 900: 890: 888: 880: 879: 875: 868: 853: 852: 848: 839: 837: 836:. 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1702: 1700: 1697: 1695: 1692: 1690: 1687: 1685: 1682: 1680: 1677: 1675: 1672: 1670: 1667: 1665: 1662: 1660: 1657: 1655: 1652: 1650: 1647: 1645: 1642: 1640: 1637: 1635: 1632: 1630: 1627: 1625: 1622: 1620: 1617: 1615: 1612: 1610: 1607: 1605: 1602: 1600: 1597: 1595: 1592: 1590: 1587: 1585: 1582: 1580: 1577: 1575: 1572: 1570: 1567: 1565: 1562: 1560: 1557: 1555: 1552: 1550: 1547: 1545: 1542: 1540: 1537: 1535: 1532: 1530: 1527: 1525: 1522: 1520: 1516: 1515:Irreversible: 1513: 1512: 1509: 1506: 1504: 1501: 1499: 1496: 1494: 1491: 1489: 1486: 1484: 1481: 1479: 1476: 1474: 1471: 1469: 1466: 1464: 1461: 1459: 1456: 1454: 1451: 1449: 1446: 1444: 1441: 1439: 1436: 1434: 1431: 1429: 1426: 1424: 1421: 1419: 1416: 1414: 1411: 1409: 1406: 1404: 1401: 1399: 1396: 1394: 1390: 1387: 1385: 1382: 1380: 1379:Quilostigmine 1377: 1375: 1372: 1370: 1369:Physostigmine 1367: 1365: 1362: 1360: 1357: 1354: 1352: 1349: 1347: 1344: 1342: 1339:; Stigmines: 1338: 1335: 1333: 1330: 1328: 1325: 1323: 1320: 1318: 1315: 1313: 1310: 1308: 1305: 1303: 1300: 1298: 1295: 1293: 1290: 1288: 1285: 1283: 1280: 1278: 1275: 1273: 1270: 1268: 1265: 1263: 1260: 1258: 1255: 1253: 1250: 1248: 1245: 1243: 1240: 1238: 1237:Chloropropham 1235: 1233: 1230: 1228: 1225: 1223: 1220: 1218: 1215: 1213: 1210: 1208: 1205: 1203: 1200: 1198: 1195: 1193: 1190: 1188: 1184: 1181: 1179: 1175: 1174: 1172: 1167: 1161: 1155: 1152: 1150: 1147: 1145: 1142: 1140: 1137: 1135: 1132: 1130: 1127: 1125: 1122: 1120: 1117: 1115: 1112: 1110: 1107: 1105: 1102: 1100: 1097: 1094: 1093: 1091: 1086: 1080: 1077: 1073: 1067: 1063: 1059: 1056: 1052: 1049: 1048:Acetylcholine 1042: 1037: 1035: 1030: 1028: 1023: 1022: 1019: 1008: 1004: 1000: 996: 993:(7): 389–92. 992: 988: 981: 978: 966: 960: 958: 954: 949: 947:0-85404-499-X 943: 939: 938: 930: 928: 924: 912: 908: 902: 899: 887: 883: 877: 874: 869: 863: 859: 858: 850: 847: 835: 829: 826: 823: 819: 814: 812: 810: 808: 806: 804: 802: 800: 796: 785:on 2008-05-11 784: 780: 774: 772: 768: 764: 757: 755: 751: 744: 742: 739: 731: 729: 725: 718: 716: 715:metabolites. 709: 707: 704: 700: 695: 688: 686: 679: 677: 674: 671: 667: 655: 649: 643: 613: 610: 606: 605: 595: 592: 588: 587: 584: 581: 578: 574: 573: 569: 564: 560: 557: 553: 552: 548: 546: 541: 537: 532: 531: 527: 526: 521: 516: 512: 510: 507: 506: 502: 500: 497: 496: 492: 489: 485: 484: 480: 478: 477:Boiling point 475: 474: 470: 468: 467:Melting point 465: 464: 460: 458: 455: 454: 450: 447: 446: 439: 437: 434: 433: 406: 403: 399: 398: 393: 384: 380: 373: 362: 358: 351: 343: 339: 338:DTXSID3037545 335: 334: 332: 322: 318: 317: 310: 306: 305: 303: 301: 298: 297: 290: 286: 285: 283: 277: 273: 272: 265: 264: 262: 260: 255: 254: 250: 246: 243: 241: 239:ECHA InfoCard 236: 235: 228: 224: 223: 221: 219: 216: 215: 208: 204: 203: 201: 199: 196: 195: 188: 184: 183: 181: 179: 176: 175: 168: 164: 163: 161: 157: 152: 151: 144: 140: 139: 137: 134: 130: 129: 124: 119: 111: 103: 99: 94: 86: 81: 73: 68: 65:Ethiofencarb 56: 53:November 2017 46: 42: 36: 34: 29:This article 27: 18: 17: 2667: 2661:α-Latrotoxin 2649: 2619: 2584: 2553: 2511: 2485: 2470: 2414:Rivastigmine 2380: 2334:Reactivators 2307:Ungiminorine 2262:Kobophenol A 2227:Coronaridine 2217:Bulbocapnine 2212:Arisugacin A 2188: 2173: 2059:Tebupirimfos 1939:Phosphamidon 1844:Methidathion 1749:Fenitrothion 1574:Chlorpyrifos 1514: 1389:Terestigmine 1384:Rivastigmine 1346:Eptastigmine 1297:Phenmedipham 1267:Formparanate 1252:Ethiofencarb 1251: 1185:Carbamates: 1182: 1176: 1095: 990: 986: 980: 969:. Retrieved 936: 914:. Retrieved 910: 901: 889:. Retrieved 885: 876: 856: 849: 838:. Retrieved 828: 787:. Retrieved 783:the original 762: 735: 726: 722: 713: 698: 696: 692: 683: 666:Ethiofencarb 665: 664: 582: 544: 534:Main hazards 523: 207:ChEMBL493480 126:Identifiers 117: 116:α-Ethylthio- 113:Other names 50: 30: 2512:Inhibitors: 2489:Coluracetam 2471:Inhibitors: 2441:Transporter 2381:Inhibitors: 2353:Pralidoxime 2247:Cyclanoline 2197:α-Viniferin 2094:Trichlorfon 1859:Metrifonate 1774:Fosthiazate 1759:Fluorotabun 1634:Dicrotophos 1589:Crotylsarin 1433:Huperzine A 1428:Galantamine 1423:Edrophonium 1356:Neostigmine 1351:Ganstigmine 1317:Propamocarb 1262:Formetanate 1247:Ethienocarb 1227:Carbosulfan 1217:Carbetamide 1212:Carbendazim 1183:Reversible: 1096:Inhibitors: 916:26 November 891:26 November 673:insecticide 577:Signal word 528:(OHS/OSH): 448:Appearance 395:Properties 245:100.045.423 187:CHEBI:38483 2743:Thioethers 2727:Categories 2676:versutoxin 2672:robustoxin 2546:Inhibitors 2535:modulators 2486:Enhancers: 2447:modulators 2404:Ladostigil 2394:Conodurine 2389:Affinisine 2302:Ungeremine 2277:Phosacetim 2237:Corynoline 2232:Corydaline 2222:Conodurine 2207:Affinisine 2143:Demecarium 2141:; Others: 2054:Tabun (GA) 2044:Soman (GD) 2034:Sarin (GB) 1954:Profenofos 1814:Isoxathion 1799:Guanitoxin 1769:Formothion 1744:Fenamiphos 1674:Disulfoton 1669:Dioxathion 1659:Dimethoate 1629:Dichlorvos 1463:Ladostigil 1453:Ipidacrine 1398:Ambenonium 1393:Acotiamide 1391:; Others: 1364:Phenserine 1341:Distigmine 1332:Thiodicarb 1307:Pirimicarb 1272:Methiocarb 1257:Fenobucarb 1232:Chlorbufam 1222:Carbofuran 1197:Bendiocarb 1178:Inhibitors 1072:modulators 1058:modulators 1051:metabolism 971:2012-11-11 840:2012-11-11 789:2012-11-11 745:References 732:Regulation 710:Metabolism 556:Pictograms 499:Solubility 436:Molar mass 309:FY0YB813XV 218:ChemSpider 154:3D model ( 143:29973-13-5 133:CAS Number 33:unbalanced 2658:agonists: 2642:Enhancers 2515:Vesamicol 2399:Cymserine 2348:Obidoxime 2343:Methoxime 2257:Harmaline 2252:Cymserine 2242:Crimidine 2189:Unsorted: 2084:Triazofos 2024:Ro 3-0433 2019:Ro 3-0422 2014:Ro 3-0419 2009:Ro 3-0417 2004:Ro 3-0412 1999:Ro 3-0411 1994:Ro 3-0397 1989:Ro 3-0352 1984:Ro 3-0351 1979:Ro 3-0347 1974:Ro 3-0346 1969:Ro 3-0340 1959:Prothoate 1929:Phosfolan 1924:Phosalone 1909:Parathion 1894:Omethoate 1864:Mevinphos 1829:Malathion 1819:Leptophos 1724:Endothion 1604:Demephion 1594:Cyanophos 1584:Coumaphos 1554:Cadusafos 1549:Bensulide 1544:BAY-29952 1508:Zanapezil 1468:Minaprine 1448:Huprine Y 1443:Huprine X 1438:Huprine W 1408:Donepezil 1337:Thiofanox 1312:Promecarb 1302:Pinmicarb 1282:Metolcarb 1242:Dimetilan 1202:Bufencarb 1192:Aminocarb 1144:CM-54,903 1055:transport 818:CID 34766 670:carbamate 627:P301+P312 547:labelling 513:0.94 mPa 266:249-981-9 258:EC Number 45:talk page 2698:See also 2682:Crotoxin 2384:Affinine 2317:BW284C51 2272:Lycorine 2202:Affinine 2192:α-Pinene 2170:Onchidal 2089:Tribufos 2069:Terbufos 2039:Schradan 1904:Paraoxon 1824:Malaoxon 1754:Fenthion 1739:Ethoprop 1624:Diazinon 1619:Dialifor 1524:Acephate 1458:Itopride 1403:Caffeine 1327:Propoxur 1277:Methomyl 1207:Carbaryl 1187:Aldicarb 1007:19796510 518:Hazards 2668:Others: 2620:Others: 2556:SNAP-25 2529:Release 2419:Tacrine 2327:3152 CT 2292:Taspine 2064:Temefos 1964:R-16661 1934:Phosmet 1919:Phorate 1869:Mipafox 1834:Mazidox 1764:Fonofos 1709:EA-4352 1704:EA-3148 1699:EA-2613 1694:EA-2192 1689:EA-2098 1684:EA-2054 1679:EA-2012 1654:Dimefox 1609:Demeton 1503:Tacrine 1498:TL-1238 1418:EA-4056 1413:EA-3990 1322:Propham 1287:Miotine 822:PubChem 583:Warning 457:Density 276:PubChem 39:Please 31:may be 2029:Ronnel 1944:Phoxim 1734:Ethion 1529:Armine 1493:TL-599 1488:T-1194 1483:T-1152 1478:T-1123 1292:Oxamyl 1066:Enzyme 1005:  944:  864:  719:Safety 441:225.31 379:SMILES 198:ChEMBL 96:Names 2500:VAChT 2322:TMTFA 1884:Naled 1789:GT-45 1779:GD-42 1129:AF64A 820:from 668:is a 357:InChI 289:34766 227:31991 178:ChEBI 156:JSmol 2652:LPHN 2587:VAMP 2369:BChE 1879:MSPI 1165:AChE 1139:BETA 1134:B115 1084:ChAT 1053:and 1003:PMID 942:ISBN 918:2017 893:2017 862:ISBN 639:P501 635:P391 631:P330 623:P273 619:P270 615:P264 601:H410 597:H302 300:UNII 2459:CHT 1729:EPN 995:doi 545:GHS 326:EPA 279:CID 2729:: 2674:, 2629:, 2610:, 2606:, 2602:, 2575:, 2571:, 2336:: 2162:, 2158:, 2154:, 2139:VX 2134:VR 2129:VS 2124:VP 2119:VM 2114:VG 2109:VE 1794:GV 1784:GH 1001:. 991:33 989:. 956:^ 926:^ 909:. 884:. 798:^ 770:^ 753:^ 637:, 633:, 629:, 625:, 621:, 617:, 599:, 549:: 417:15 411:11 2678:) 2633:) 2625:( 2614:) 2612:G 2608:F 2604:D 2600:B 2598:( 2579:) 2577:E 2573:C 2569:A 2567:( 2537:) 2533:( 2449:) 2445:( 2178:) 2172:( 2166:) 2164:4 2160:3 2156:2 2152:1 2150:( 1180:: 1074:) 1070:( 1040:e 1033:t 1026:v 1009:. 997:: 974:. 950:. 920:. 895:. 870:. 843:. 792:. 699:N 429:S 426:2 423:O 420:N 414:H 408:C 328:) 324:( 158:) 118:o 55:) 51:( 47:. 37:.

Index

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Preferred IUPAC name
CAS Number
29973-13-5
JSmol
Interactive image
ChEBI
CHEBI:38483
ChEMBL
ChEMBL493480
ChemSpider
31991
ECHA InfoCard
100.045.423
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EC Number
PubChem
34766
UNII
FY0YB813XV
CompTox Dashboard
DTXSID3037545
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InChI
SMILES
Chemical formula

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