Knowledge (XXG)

Hives

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these hives are not the same as those witnessed with most urticariae. Instead, the protrusion in the affected areas is typically more spread out. The hives may last from eight hours to three days. The source of the pressure on the skin can happen from tight fitted clothing, belts, clothing with tough straps, walking, leaning against an object, standing, sitting on a hard surface, etc. The areas of the body most commonly affected are the hands, feet, trunk, abdomen, buttocks, legs and face. Although this appears to be very similar to dermatographism, the cardinal difference is that the swelled skin areas do not become visible quickly and tend to last much longer. This form of the skin disease is, however, rare.
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of severe disease but should not be used for long term due to their long list of side effects. Step 2 consists of increasing the dose of the current antihistamine, adding other antihistamines, or adding a leukotriene receptor antagonist such as montelukast. Step 3 consists of adding or replacing the current treatment with hydroxyzine or doxepin. If the individual doesn't respond to steps 1–3 then they are considered to have refractory symptoms. At this point, anti-inflammatory medications (dapsone, sulfasalazine), immunosuppressants (cyclosporin, sirolimus) or other medications like
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prostaglandin and leukotriene activity. It is helpful in therapy-refractory cases and is contraindicated in people with G6PD deficiency. Sulfasalazine, a 5-ASA derivative, is thought to alter adenosine release and inhibit IgE mediated mast cell degranulation, Sulfasalazine is a good option for people with anemia who cannot take dapsone. Hydroxychloroquine is an antimalarial agent that suppresses T lymphocytes. It has a low cost however it takes longer than dapsone or sulfasalazine to work.
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against the skin of the forearm for 1 to 5 minutes. A distinct hive should develop if a person has cold urticaria. This is different from the normal redness that can be seen in people without cold urticaria. People with cold urticaria need to learn to protect themselves from a hasty drop in body temperature. Regular antihistamines are not generally efficacious. One particular antihistamine, cyproheptadine (Periactin), has been found to be useful. The tricyclic antidepressant
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two hours. This kind of hives does not seem to be stimulated by histamine discharge like the other physical hives. Most researchers believe this condition is actually skin sensitivity to additives in the water, such as chlorine. Water urticaria is diagnosed by dabbing tap water and distilled water to the skin and observing the gradual response. Aquagenic urticaria is treated with capsaicin (Zostrix) administered to the chafed skin. This is the same treatment used for
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the symptoms. This method must be used with caution and only with the appropriate resuscitative measures at hand. EU can be differentiated from cholinergic urticaria by the hot water immersion test. In this test, the person is immersed in water at 43 °C (109.4 °F). Someone with EU will not develop hives, while a person with cholinergic urticaria will develop the characteristic small hives, especially on the neck and chest.
501: 908: 65: 583:(also known as dermatographism or "skin writing") is marked by the appearance of weals or welts on the skin as a result of scratching or firm stroking of the skin. Seen in 4–5% of the population, it is one of the most common types of urticaria, in which the skin becomes raised and inflamed when stroked, scratched, rubbed, and sometimes even slapped. 305: 297: 289: 1000:
Vibratory angioedema is diagnosed by holding a vibrating device such as a laboratory vortex machine against the forearm for four minutes. Speedy swelling of the whole forearm extending into the upper arm is also noted later. The principal treatment is avoidance of vibratory stimulants. Antihistamines have also been proven helpful.
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Leukotrienes are released from mast cells along with histamine. The medications, montelukast and zafirlukast block leukotriene receptors and can be used as add on treatment or in isolation for people with CU. It is important to note that these medications may be more beneficial for people with NSAID
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is acknowledged to stabilise mast cells and prevent histamine release, and has been effective in treating this hives disorder. Avoiding exercise or foods that cause the mentioned symptoms is very important. In particular circumstances, tolerance can be brought on by regular exercise, but this must be
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The cold type of urticaria is caused by exposure of the skin to extreme cold, damp and windy conditions; it occurs in two forms. The rare form is hereditary and becomes evident as hives all over the body 9 to 18 hours after cold exposure. The common form of cold urticaria demonstrates itself with the
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Pacor ML, Di Lorenzo G, Corrocher R (2001). "Efficacy of leukotriene receptor antagonist in chronic urticaria. A double-blind, placebo-controlled comparison of treatment with montelukast and cetirizine in patients with chronic urticaria with intolerance to food additive and/or acetylsalicylic acid".
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In those with chronic urticaria, defined as either continuous or intermittent symptoms lasting longer than 6 weeks, 35% of people are symptom free 1 year after treatment, while 29% have a reduction in their symptoms. Those with a longer disease duration typically have a worse prognosis, with greater
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This very rare form of angioedema develops in response to contact with vibration. In vibratory angioedema, symptoms develop within two to five minutes after contact with a vibrating object and abate after about an hour. People with this disorder do not experience dermographism or pressure urticaria.
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urticaria is defined as the presence of hives which persist for greater than six weeks. Some of the more severe chronic cases have lasted more than 20 years. A survey indicated chronic urticaria lasted a year or more in more than 50% of those affected and 20 years or more in 20% of them. Provocative
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This type of hives can occur right away, precisely after a pressure stimulus or as a deferred response to sustained pressure being enforced to the skin. In the deferred form, the hives only appear after about six hours from the initial application of pressure to the skin. Under normal circumstances,
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Oral glucocorticoids are effective in controlling symptoms of chronic hives. However, they have an extensive list of adverse effects, such as adrenal suppression, weight gain, osteoporosis, hyperglycemia, etc. Therefore, their use should be limited to a couple of weeks. In addition, one study found
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Treatment guidelines for the management of chronic hives have been published. According to the 2014 American practice parameters, treatment involves a stepwise approach. Step 1 consists of second generation, H1 receptor blocking antihistamines. Systemic glucocorticoids can also be used for episodes
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is similar to hives, but in angioedema, the swelling occurs in a lower layer of the dermis than in hives, as well as in the subcutis. This swelling can occur around the mouth, eyes, in the throat, in the abdomen, or in other locations. Hives and angioedema sometimes occur together in response to an
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EU sometimes occurs only when someone exercises within 30 minutes of eating particular foods, such as wheat or shellfish. For these individuals, exercising alone or eating the injuring food without exercising produces no symptoms. EU can be diagnosed by having the person exercise and then observing
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This type of urticaria is also termed rare and occurs upon contact with water. The response is not temperature-dependent and the skin appears similar to the cholinergic form of the disease. The appearance of hives is within one to 15 minutes of contact with the water and can last from 10 minutes to
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Severe reactions can be seen with exposure to cold water; swimming in cold water is the most common cause of a severe reaction. This can cause a massive discharge of histamine, resulting in low blood pressure, fainting, shock and even loss of life. Cold urticaria is diagnosed by dabbing an ice cube
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with red, raised, itchy bumps. Hives may burn or sting. The patches of rash may appear on different body parts, with variable duration from minutes to days, and does not leave any long-lasting skin change. Fewer than 5% of cases last for more than six weeks (a condition known as chronic urticaria).
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which completely resolve within six weeks. Acute urticaria becomes evident a few minutes after the person has been exposed to an allergen. The outbreak may last several weeks, but usually the hives are gone in six weeks. Typically, the hives are a reaction to food, but in about half the cases, the
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The condition was first distinguished in 1980. People with exercise urticaria (EU) experience hives, itchiness, shortness of breath and low blood pressure five to 30 minutes after beginning exercise. These symptoms can progress to shock and even sudden death. Jogging is the most common exercise to
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It stands in contrast to the linear reddening that does not itch seen in healthy people who are scratched. In most cases, the cause is unknown, although it may be preceded by a viral infection, antibiotic therapy, or emotional upset. Dermatographism is diagnosed by applying pressure by stroking or
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About 20% of people are affected. Cases of short duration occur equally in males and females, lasting a few days and without leaving any long-lasting skin changes. Cases of long duration are more common in females. Cases of short duration are more common among children while cases of long duration
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About 20% of people are affected at some point in their lives. Cases of short duration occur equally in males and females while cases of long duration are more common in females. Cases of short duration are more common among children while cases of long duration are more common among those who are
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rapid onset of hives on the face, neck, or hands after exposure to cold. Cold urticaria is common and lasts for an average of five to six years. The population most affected is young adults, between 18 and 25 years old. Many people with the condition also have dermographism and cholinergic hives.
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Immunosuppressants used for CU include cyclosporine, tacrolimus, sirolimus, and mycophenolate. Calcineurin inhibitors, such as cyclosporine and tacrolimus, inhibit cell responsiveness to mast cell products and inhibit T cell activity. They are preferred by some experts to treat severe symptoms.
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Chronic hives can be difficult to treat and lead to significant disability. Unlike the acute form, 50–80% of people with chronic hives have no identifiable triggers. But 50% of people with chronic hives will experience remission within 1 year. Overall, treatment is geared towards symptomatic
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is a related condition (also from allergic and nonallergic causes), though fluid leakage is from much deeper blood vessels in the subcutaneous or submucosal layers. Individual hives that are painful, last more than 24 hours, or leave a bruise as they heal are more likely to be a more serious
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Other options for refractory symptoms of chronic hives include anti-inflammatory medications, omalizumab, and immunosuppressants. Potential anti-inflammatory agents include dapsone, sulfasalazine, and hydroxychloroquine. Dapsone is a sulfone antimicrobial agent and is thought to suppress
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Sirolimus and mycophenolate have less evidence for their use in the treatment of chronic hives but reports have shown them to be efficacious. Immunosuppressants are generally reserved as the last line of therapy for severe cases due to their potential for serious adverse effects.
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was approved by the FDA in 2014 for people with hives 12 years old and above with chronic hives. It is a monoclonal antibody directed against IgE. Significant improvement in pruritus and quality of life was observed in a phase III, multicenter, randomized control trial.
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over a long period of time is requested in hopes of getting new insight. No evidence shows regular allergy testing results in identification of a problem or relief for people with chronic hives. Regular allergy testing for people with chronic hives is not recommended.
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Hives can also be classified by the purported causative agent. Many different substances in the environment may cause hives, including medications, food and physical agents. In perhaps more than 50% of people with chronic hives of unknown cause, it is due to an
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scratching the skin. The hives should develop within a few minutes. Unless the skin is highly sensitive and reacts continually, treatment is not needed. Taking antihistamines can reduce the response in cases that are annoying to the person.
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Chung, Man Cheung; Symons, Christine; Gilliam, Jane; Kaminski, Edward R. (2010). "The relationship between posttraumatic stress disorder, psychiatric comorbidity, and personality traits among patients with chronic idiopathic urticaria".
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management. Individuals with chronic hives may need other medications in addition to antihistamines to control symptoms. People who experience hives with angioedema require emergency treatment as this is a life-threatening condition.
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antibodies to high-affinity cell surface receptors. Basophils and other inflammatory cells are also seen to release histamine and other mediators, and are thought to play an important role, especially in chronic urticarial diseases.
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Shaker, Marcus; Oppenheimer, John; Wallace, Dana; Lang, David M.; Rambasek, Todd; Dykewicz, Mark; Greenhawt, Matthew (July 2020). "Optimizing Value in the Evaluation of Chronic Spontaneous Urticaria: A Cost-Effectiveness Analysis".
715: 966:), cold temperatures, warm temperatures, or light in an attempt to provoke symptoms and aid in the diagnosis. The history of physical examination guide the diagnosis of chronic urticaria, with extensive lab testing not recommended. 3643: 875:. Ingestion of free histamine released by bacterial decay in fish flesh may result in a rapid-onset, allergic-type symptom complex which includes hives. However, the hives produced by scombroid is reported not to include wheals. 1123:
symptom severity. Chronic urticaria is often accompanied by an intense pruritus, and other symptoms associated with a reduced quality of life and a high burden of co-morbid psychiatric conditions such as anxiety and depression.
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which is provoked during sweating events such as exercise, bathing, staying in a heated environment, or emotional stress. The hives produced are typically smaller than classic hives and are generally shorter-lasting.
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AU Shahar E, Bergman R, Guttman-Yassky E, Pollack S (2006). "Treatment of severe chronic idiopathic urticaria with oral mycophenolate mofetil in patients not responding to antihistamines and/or corticosteroids".
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Kozel, Martina M.A.; Bossuyt, Patrick M.M.; Mekkes, Jan R.; Bos, Jan D. (2003). "Laboratory tests and identified diagnoses in patients with physical and chronic urticaria and angioedema: A systematic review".
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with red, raised, itchy bumps. They may also burn or sting. Hives can appear anywhere on the surface of the skin. Whether the trigger is allergic or not, a complex release of inflammatory mediators, including
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The skin reaction usually becomes evident soon after the scratching and disappears within 30 minutes. Dermatographism is the most common form of a subset of chronic hives, acknowledged as "physical hives".
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Hive-like rashes commonly accompany viral illnesses, such as the common cold. They usually appear three to five days after the cold has started, and may even appear a few days after the cold has resolved.
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has been found to be effective blocking agents of histamine. Finally, a medication named ketotifen, which keeps mast cells from discharging histamine, has also been employed with widespread success.
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trigger is unknown. Common foods may be the cause, as well as bee or wasp stings, or skin contact with certain fragrances. Acute viral infection is another common cause of acute urticaria (viral
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Tebbe, Beate; Geilen, Christoph C.; Schulzke, Jörg-Dieter; Bojarski, Christian; Radenhausen, Michael; Orfanos, Constantin E. (1996). "Helicobacter pylori infection and chronic urticaria".
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People who do not respond to the maximum dose of H1 antihistamines may benefit from increasing the dose further, then to switching to another non-sedating antihistamine, then to adding a
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AU Erbagci Z SO (2002). "The leukotriene receptor antagonist montelukast in the treatment of chronic idiopathic urticaria: a single-blind, placebo-controlled, crossover clinical study".
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Maurer, Marcus; Rosén, Karin; Hsieh, Hsin-Ju; Saini, Sarbjit; Grattan, Clive; Gimenéz-Arnau, Ana; Agarwal, Sunil; Doyle, Ramona; Canvin, Janice; Kaplan, Allen; Casale, Thomas (2013).
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of urticaria. Dermal edema and a sparse superficial predominantly perivascular and interstitial infiltrate of lymphocytes and eosinophils without signs of vasculitis (dashed arrow).
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Chung, Man Cheung; Symons, Christine; Gilliam, Jane; Kaminski, Edward R. (2010). "Stress, psychiatric co-morbidity and coping in patients with chronic idiopathic urticaria".
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Engin, B; Uguz, F; Yilmaz, E; Ozdemir, M; Mevlitoglu, I (2007). "The levels of depression, anxiety and quality of life in patients with chronic idiopathic urticaria".
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are more common among those who are middle aged. Fewer than 5% of cases last for more than six weeks. The condition frequently recurs. In half of cases of hives, the
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Tarbox, James A.; Gutta, Ravi C.; Radojicic, Cristine; Lang, David M. (2011). "Utility of routine laboratory testing in management of chronic urticaria/angioedema".
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may also be used. Keeping the environmental temperature cool is also useful. For cases that last more than six weeks long term antihistamine therapy is indicated.
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Chronic urticaria is usually seen in those older than 40 years, it is more common in women. The prevalence of chronic urticaria is 0.23% in the United States.
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since the 1940s. A large body of evidence demonstrates an association between this condition and both poor emotional well-being and reduced health-related
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located on skin mast cells. Chronic stimulation of this receptor leads to chronic hives. People with hives often have other autoimmune conditions, such as
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hives are the result of an autoimmune trigger. Roughly 50% of people with chronic urticaria spontaneously develop autoantibodies directed at the receptor
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Hirschmann, J. V.; Lawlor, F; English, JS; Louback, JB; Winkelmann, RK; Greaves, MW (1987). "Cholinergic Urticaria - A Clinical and Histologic Study".
4889: 5696: 5691: 5292: 891:. A link between stress and this condition has also been shown. Some cases have been thought to be due to stress, including an association between 5647: 5469: 4443: 3365:
Phan, NQ; Bernhard, JD; Luger, TA; Ständer, S (October 2010). "Antipruritic treatment with systemic μ-opioid receptor antagonists: a review".
566:. Urushiol is spread by contact but can be washed off with a strong grease- or oil-dissolving detergent and cool water and rubbing ointments. 472:, which is in many processed foods, to be the most common cause of immediate contact urticaria. Another food allergy that can cause hives is 2566: 2442: 4717: 2549: 1085:
that systemic glucocorticoids combined with antihistamines did not hasten the time to symptom control compared with antihistamines alone.
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Kozel MM, Mekkes JR, Bossuyt PM, Bos JD (2001). "Natural course of physical and chronic urticaria and angioedema in 220 patients".
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Mechanisms other than allergen-antibody interactions are known to cause histamine release from mast cells. Many drugs, for example
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This form of the disease occurs on areas of the skin exposed to the sun; the condition becomes evident within minutes of exposure.
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The skin lesions of urticarial disease are caused by an inflammatory reaction in the skin, causing leakage of capillaries in the
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Uguz, Faruk; Engin, Burhan; Yilmaz, Ertan (2008). "Axis I and Axis II diagnoses in patients with chronic idiopathic urticaria".
863:. The occurrence of drug-induced solar urticaria may be associated with porphyrias. This may be caused by IgG binding, not IgE. 690:
cause EU, but it is not induced by a hot shower, fever, or with fretfulness. This differentiates EU from cholinergic urticaria.
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Langan, EA; Nie, Z; Rhodes, LE (Sep 2010). "Melanotropic peptides: more than just 'Barbie drugs' and 'sun-tan jabs'?".
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Giang, Jenny; Seelen, Marc A. J.; van Doorn, Martijn B. A.; Rissmann, Robert; Prens, Errol P.; Damman, Jeffrey (2018).
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are sometimes used in addition to H1-antagonists to treat urticaria, but there is limited evidence for their efficacy.
5544: 5347: 5077: 5053: 4304: 3835: 3790: 2305: 1172:, meaning stinging hair or nettle, as the classical presentation follows the contact with a perennial flowering plant 1031:, are not recommended as a first line therapy as they block both brain and peripheral H1 receptors, causing sedation. 5575: 5253: 4998: 4859: 4657: 4377: 1178:. The history of urticaria dates back to 1000–2000 BC with its reference as a wind-type concealed rash in the book 1008:
The mainstay of therapy for both acute and chronic hives is education, avoiding triggers and using antihistamines.
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skin challenge testing may be done in those with chronic urticaria, in which the skin is exposed to pressure (
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Hives including chronic spontaneous hives can be a complication and symptom of a parasitic infection, such as
5392: 5155: 5048: 4791: 4687: 4382: 4101: 4073: 3703: 1073: 844: 2875: 681:. Antihistamines are of questionable benefit in this instance since histamine is not the causative factor. 5523: 4662: 4574: 3890: 1737:; Matjevic, L. J.; Mitchel, F. B. (1997). "Physical urticaria: Classification and diagnostic guidelines". 1059: 787: 406: 246: 163: 2931:
Kim S, Baek S, Shin B, Yoon SY, Park SY, Lee T, Lee YS, Bae YJ, Kwon HS, Cho YS, Moon HB, Kim TB (2013).
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Champion, R. H.; Roberts, S. O. B.; Carpenter, R. G.; Roger, J. H. (1969). "Urticaria and Angio-Oedema".
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Diagnosis is typically based on the appearance. The cause of chronic hives can rarely be determined.
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Moore-Robinson, Miriam; Warin, Robert P. (1968). "Some Clikical Aspects of Cholhstergic Urticaria".
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Griffiths, Christopher; Barker, Jonathan; Bleiker, Tanya; Chalmers, Robert; Creamer, Daniel (2016).
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in 1879 brought urticaria and similar conditions under a comprehensive idea of allergic conditions.
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Prevention is by avoiding whatever it is that causes the condition. Treatment is typically with
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being preferred due to less risk of sedation and cognitive impairment. In refractory cases,
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Huang, Cheng-zhi; Jiang, Zhi-hui; Wang, Jian; Luo, Yue; Peng, Hua (29 November 2019).
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Kathryn L. McCance; Sue E. Huether; Valentina L. Brashers; Neal S. Rote, eds. (2014).
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Jafilan, L; James, C (December 2015). "Urticaria and Allergy-Mediated Conditions".
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Acute and chronic hives are visually indistinguishable on visual inspection alone.
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Multiple subtypes have been elucidated, each of which require distinct treatment.
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Kolkhir, P.; Balakirski, G.; Merk, HF.; Olisova, O.; Maurer, M. (December 2015).
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in the 4th century first described urticaria as "knidosis" after the Greek word
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contact is commonly mistaken for urticaria. This rash is caused by contact with
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and airway support. Taking antihistamines prior to exercise may be effective.
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Morgan M (2009). "Treatment of refractory chronic urticaria with sirolimus".
3114:"Omalizumab for the Treatment of Chronic Idiopathic or Spontaneous Urticaria" 2899: 2842: 2270: 2261: 206:, cold temperature, or vibration may also be a trigger. In half of cases the 4739: 4652: 4602: 4366: 3953: 3925: 3830: 3665: 3609: 3593: 3526: 3275:"Higher Levels of Depression and Anxiety in Patients with Chronic Urticaria" 3003: 2600: 1711: 1659:"Chronic spontaneous urticaria and internal parasites – a systematic review" 1197: 740: 736: 716:
List of human leukocyte antigen alleles associated with cutaneous conditions
702: 453: 445: 418: 394: 362: 330: 318: 313: 211: 207: 187: 128: 3456: 3434: 3386: 3343: 3308: 3251: 3215: 3180: 3139: 3090: 3047: 3011: 2976: 2917: 2860: 2801: 2752: 2698: 2649: 2608: 2523: 2408: 2369: 2288: 2221: 2186: 2146: 2131:"Stress, Insomnia, and Chronic Idiopathic Urticaria – a Case-Control Study" 2107: 2072: 2037: 1948: 1899: 1684: 1552: 1441: 1345: 3130: 3113: 2673:"The diagnosis and management of acute and chronic urticaria: 2014 update" 2479: 1858: 1815: 1758: 1719: 1643: 1433: 5064: 4961: 4702: 4677: 4299: 4279: 4215: 4169: 4111: 4048: 3990: 3810: 3759: 3688: 2400: 1698:
Jedele, Kerry B.; Michels, Virginia V. (1991). "Familial dermographism".
988: 950: 828: 783: 756: 678: 555: 414: 31: 3290: 922:
may be useful to determine the allergy. In some cases regular extensive
64: 5159: 4476: 4330: 4240: 4159: 4146: 4096: 4025: 3749: 3744: 3739: 2129:
Yang, Hsiao-Yu; Sun, Chee-Ching; Wu, Yin-Chang; Wang, Jung-Der (2005).
645: 422: 390: 382: 378: 195: 3509: 2640: 2623: 1964:
Pathophysiology: the biologic basis for disease in adults and children
1675: 1658: 1070:. Steroids are often associated with rebound hives once discontinued. 304: 296: 288: 5528: 4088: 4033: 3800: 3795: 3769: 3678: 3521: 1247: 945: 721: 697:
The immediate symptoms of this type are treated with antihistamines,
377:
Drugs that have caused allergic reactions evidenced as hives include
366: 215: 132: 3069:
Boehm I, et al. (Jul 1999). "Urticaria treated with dapsone".
2874:
Fedorowicz, Zbys; van Zuuren, Esther J; Hu, Nianfang (2012-03-14).
1873: 292:
Hives on the left chest wall. Notice that they are slightly raised.
194:
Hives frequently occur following an infection or as a result of an
5495: 5163: 3754: 906: 725: 461: 303: 295: 287: 270: 265:
middle aged. Hives have been described at least since the time of
751:
Histamine and other proinflammatory substances are released from
4335: 3854: 3673: 2766:
Sharma, M; Bennett, C; Cohen, SN; Carter, B (14 November 2014).
5116: 4706: 3625: 1923:"Pathogenesis of Cholinergic Urticaria in Relation to Sweating" 1020:
can be used. These options are explained in more detail below.
835:
molecule. Also, a diverse group of signaling substances called
2088:
Journal of the European Academy of Dermatology and Venereology
1878:
Journal of the European Academy of Dermatology and Venereology
760: 495: 465: 1872:
Nakamizo, S.; Egawa, G.; Miyachi, Y.; Kabashima, K. (2012).
1497: 1495: 2504:
The Journal of Allergy and Clinical Immunology: In Practice
2012:
Mitchell, John H; Curran, Charles A; Myers, Ruth N (1947).
1478:(9 ed.). John Wiley & Sons. p. Chapter 42.3. 1364:
Zuberbier, Torsten; Grattan, Clive; Maurer, Marcus (2010).
27:
Skin disease characterized by red, raised, and itchy bumps
1966:(Seventh ed.). Elsevier – Health Sciences Division. 361:
reaction. Risk factors include having conditions such as
1420:
Lang, David M. (1 September 2022). "Chronic Urticaria".
883:
Chronic idiopathic hives has been anecdotally linked to
831:, can induce direct histamine release not involving any 512: 2425:
James, William; Berger, Timothy; Elston, Dirk (2005).
755:
in the skin and tissues in response to the binding of
3413:
Poonawalla T, Kelly B (2009). "Urticaria: A review".
2768:"H1-antihistamines for chronic spontaneous urticaria" 2306:"Five Things Physicians and Patients Should Question" 2245:"Complement Activation in Inflammatory Skin Diseases" 1921:
Bito, Toshinori; Sawada, Yu; Tokura, Yoshiki (2012).
1530: 1528: 1370:. Springer Science & Business Media. p. 38. 3499: 229:, with the second generation antihistamines such as 5734:
Skin conditions resulting from errors in metabolism
5669: 5635: 5626: 5604: 5558: 5537: 5518: 5488: 5442: 5427: 5386: 5338: 5331: 5317: 5287: 5262: 5177: 5154: 5062: 5024: 4969: 4960: 4933: 4882: 4773: 4757: 4738: 4621: 4588: 4532: 4517: 4508: 4465: 4436: 4415: 4406: 4359: 4318: 4287: 4276: 4269: 4258: 4203: 4145: 4087: 4024: 3944: 3873: 3862: 3853: 3768: 3732: 3664: 3657: 3573: 3503: 2429:
Andrews' Diseases of the Skin: Clinical Dermatology
2317:
American Academy of Allergy, Asthma, and Immunology
169: 151: 138: 122: 111: 103: 93: 76: 54: 49: 2343: 2341: 3652:Diseases of the skin and appendages by morphology 2876:"Histamine H2-receptor antagonists for urticaria" 2014:"Some Psychosomatic Aspects of Allergic Diseases" 452:. The most common food allergies in children are 210:. Risk factors include having conditions such as 5614:Transfusion-associated graft-versus-host disease 2710: 2708: 2381: 2379: 2420: 2418: 895:and chronic idiopathic hives. In most cases of 3367:Journal of the American Academy of Dermatology 2389:Journal of the American Academy of Dermatology 1624:Journal of the American Academy of Dermatology 1152:have tentative evidence to support their use. 218:. Diagnosis is typically based on appearance. 5128: 4718: 4137:Pityriasis lichenoides et varioliformis acuta 3637: 444:The most common food allergies in adults are 8: 3791:Dermatofibroma (benign fibrous histiocytoma) 2300: 2298: 1475:Rook's Textbook of Dermatology, 4 Volume Set 1415: 1413: 1411: 2135:Journal of the Formosan Medical Association 1409: 1407: 1405: 1403: 1401: 1399: 1397: 1395: 1393: 1391: 1168:in 1769. It originates from the Latin word 5632: 5534: 5439: 5335: 5314: 5174: 5135: 5121: 5113: 5016:Acute generalized exanthematous pustulosis 4966: 4779: 4754: 4725: 4711: 4703: 4514: 4412: 4284: 4273: 4266: 3870: 3859: 3661: 3644: 3630: 3622: 3500: 2350:Annals of Allergy, Asthma & Immunology 1319: 1317: 1315: 1313: 1311: 1309: 1307: 1305: 1303: 1301: 1299: 1297: 1295: 1293: 1291: 1289: 63: 46: 4890:Acquired C1 esterase inhibitor deficiency 3461:. New York: Internet Dermatology Society. 3401:Clinical Allergy Diagnosis and Management 3298: 3170: 3129: 2966: 2956: 2907: 2850: 2832: 2791: 2742: 2732: 2688: 2639: 2278: 2260: 1938: 1889: 1674: 1467: 1465: 1463: 1461: 1459: 1359: 1357: 1355: 1287: 1285: 1283: 1281: 1279: 1277: 1275: 1273: 1271: 1269: 1242: 1240: 1238: 1236: 1234: 1164:was first used by the Scottish physician 1023:First generation antihistamines, such as 3415:American Journal of Clinical Dermatology 941:urticaria is defined as the presence of 732:is absorbed into the surrounding cells. 222:may be useful to determine the allergy. 5648:Allergic bronchopulmonary aspergillosis 3472:The History of Urticaria and Angioedema 2880:Cochrane Database of Systematic Reviews 2772:Cochrane Database of Systematic Reviews 1230: 1142:is being studied as a hives treatment. 4444:Disseminated intravascular coagulation 3458:The electronic textbook of Dermatology 2721:The World Allergy Organization Journal 1988:"Scombroid fish poisoning. DermNet NZ" 115:Following an infection, result, of an 5470:Post-streptococcal glomerulonephritis 4943:Episodic angioedema with eosinophilia 2326:from the original on November 3, 2012 739:and other mediators of inflammation ( 7: 3273:Tat, Tugba Songul (4 January 2019). 1851:10.1001/archderm.1987.01660280064024 1700:American Journal of Medical Genetics 1537:"Chronic urticaria and autoimmunity" 4920:Urticaria-like follicular mucinosis 2433:(10th ed.). Saunders. p.  1571:"Prescribing Information Dexedrine" 1254:from the original on 19 August 2016 879:Stress and chronic idiopathic hives 735:Hives are caused by the release of 564:urushiol-induced contact dermatitis 4226:Postinflammatory hyperpigmentation 3488:Urticaria photo library at Dermnet 3324:The British Journal of Dermatology 2563:"Hives (Urticaria and Angioedema)" 2472:10.1111/j.1365-2133.1969.tb16041.x 1808:10.1111/j.1365-2133.1968.tb11948.x 1751:10.1111/j.1398-9995.1997.tb02593.x 1733:Kontou-Fili, K.; Borici-Mazi, R.; 1535:Fraser K, Robertson L (Dec 2013). 1180:The Yellow Emperor's Inner Classic 778:Over half of all cases of chronic 312:Hives, or urticaria, is a form of 25: 5687:Autoimmune polyendocrine syndrome 4127:Transient acantholytic dermatosis 2053:Journal of Psychosomatic Research 269:. The term urticaria is from the 191:The condition frequently recurs. 5324:Hemolytic disease of the newborn 4827:Localized heat contact urticaria 4804:Secondary cold contact urticaria 4236:Idiopathic guttate hypomelanosis 3455:McGovern TW, Barkley TM (2000). 3336:10.1111/j.1365-2133.2010.09891.x 3244:10.1111/j.1365-4632.2006.02655.x 3083:10.1034/j.1398-9995.1999.00187.x 3040:10.1046/j.1365-2222.2001.01189.x 2153:from the original on 2017-09-08. 2100:10.1111/j.1468-3083.2007.02324.x 2065:10.1016/j.jpsychores.2007.08.006 2030:10.1097/00006842-194705000-00003 1891:10.1111/j.1468-3083.2011.04017.x 1559:from the original on 2016-01-31. 1521:from the original on 2016-08-21. 1384:from the original on 2016-08-21. 1089:Leukotriene-receptor antagonists 1033:Second-generation antihistamines 499: 492:Infection or environmental agent 5506:Subacute bacterial endocarditis 5368:Immune thrombocytopenic purpura 4246:Hypopigmented mycosis fungoides 3427:10.2165/0128071-200910010-00002 3118:New England Journal of Medicine 2821:BMC Pharmacology and Toxicology 2569:from the original on 2007-08-24 2179:10.1016/j.comppsych.2009.02.005 1994:from the original on 2012-02-04 1940:10.2332/allergolint.12-RAI-0485 1604:from the original on 2014-07-05 1422:New England Journal of Medicine 4799:Primary cold contact urticaria 4487:Lichen sclerosis et atrophicus 4195:Subcorneal pustular dermatosis 3821:Infantile digital fibromatosis 2892:10.1002/14651858.CD008596.pub2 2784:10.1002/14651858.CD006137.pub2 2460:British Journal of Dermatology 1796:British Journal of Dermatology 1: 5586:Postorgasmic illness syndrome 5073:Necrolytic migratory erythema 5034:Erythema annulare centrifugum 4925:Chronic spontaneous urticaria 4079:Epidermolysis bullosa simplex 3916:Langerhans cell histiocytosis 2715:Zuberbier, T (January 2012). 1990:. Dermnetnz.org. 2011-07-01. 1636:10.1016/S0190-9622(96)80086-7 1573:. GlaxoSmithKline. June 2006. 1196:for nettle. The discovery of 857:erythropoietic protoporphyria 5643:Hypersensitivity pneumonitis 4765:Urticarial allergic eruption 4555:Systemic lupus erythematosus 4310:Systemic lupus erythematosus 4001:Systemic lupus erythematosus 3208:10.1001/archdermatol.2009.13 2958:10.1371/journal.pone.0069345 2734:10.1097/WOX.0b013e3181f13432 2550:Dorland's Medical Dictionary 1584:Alexander A. Fisher (2008). 1507:. CABI. 2011. p. 1430. 897:chronic idiopathic urticaria 859:) have been associated with 808:systemic lupus erythematosus 595:Pressure or delayed pressure 542:The rash that develops from 5709:Systemic autoimmune disease 5545:Allergic contact dermatitis 5465:Hypersensitivity vasculitis 5348:Autoimmune hemolytic anemia 5054:Annular erythema of infancy 3836:Lymphangioma circumscriptum 3399:Volcheck, Gerald W. (2009) 1587:Fisher's Contact Dermatitis 867:Dietary histamine poisoning 706:under medical supervision. 5760: 5215:common allergies include: 4999:Toxic epidermal necrolysis 4860:Delayed pressure urticaria 4658:Mucous membrane pemphigoid 3379:10.1016/j.jaad.2009.08.052 3172:10.1016/j.jaci.2008.10.050 2690:10.1016/j.jaci.2014.02.036 2516:10.1016/j.jaip.2019.11.004 2362:10.1016/j.anai.2011.06.008 1504:A Dictionary of Entomology 899:, no cause is identified. 771: 713: 669: 655: 632: 607: 573: 36: 29: 5098:Necrolytic acral erythema 4989:Erythema multiforme major 4984:Erythema multiforme minor 4840: 4817: 4782: 2834:10.1186/s40360-019-0363-1 2214:10.1080/08870440802530780 1927:Allergology International 1338:10.1016/j.pop.2015.08.002 849:hereditary coproporphyria 728:which persists until the 558:and results in a form of 71: 62: 5744:Urticaria and angioedema 5460:Henoch–Schönlein purpura 5275:Eosinophilic esophagitis 4994:Stevens–Johnson syndrome 4845:Dermatographic urticaria 4423:Thrombocytopenic purpura 4069:Dermatitis herpetiformis 4054:Acute contact dermatitis 4006:Pityriasis rubra pilaris 3931:Wiskott–Aldrich syndrome 3901:Lichen simplex chronicus 3781:Epidermal inclusion cyst 2262:10.3389/fimmu.2018.00639 2167:Comprehensive Psychiatry 1367:Urticaria and Angioedema 873:scombroid food poisoning 581:Dermatographic urticaria 576:Dermatographic urticaria 570:Dermatographic urticaria 346:dermatographic urticaria 99:Red, raised, itchy bumps 30:Not to be confused with 5739:Type I hypersensitivity 5576:Hashimoto's thyroiditis 5363:Guillain–Barré syndrome 5049:Erythema gyratum repens 4688:Squamous-cell carcinoma 4683:Systemic histoplasmosis 4074:Porphyria cutanea tarda 3704:Squamous-cell carcinoma 3279:Medical Science Monitor 3004:10.1067/mai.2002.126676 2601:10.1067/mjd.2001.116217 2249:Frontiers in Immunology 2202:Psychology & Health 1839:Archives of Dermatology 1712:10.1002/ajmg.1320390216 1074:H2-receptor antagonists 845:porphyria cutanea tarda 198:such as to medication, 5677:Autoimmune adrenalitis 4733:Urticaria and erythema 4663:Cicatricial pemphigoid 4580:Acne keloidalis nuchae 4575:Folliculitis decalvans 3159:J Allergy Clin Immunol 2992:J Allergy Clin Immunol 2677:J Allergy Clin Immunol 2018:Psychosomatic Medicine 1781:"Gale - Product Login" 1060:leukotriene antagonist 915: 788:autoimmune thyroiditis 724:, and resulting in an 309: 301: 293: 247:leukotriene inhibitors 164:leukotriene inhibitors 4948:Hereditary angioedema 4865:Cholinergic urticaria 4809:Reflex cold urticaria 4565:Loose anagen syndrome 4492:Necrobiosis lipoidica 4428:Actinic/solar purpura 4102:Insect bite reactions 3891:Seborrheic dermatitis 3714:Merkel-cell carcinoma 3694:Molluscum contagiosum 3131:10.1056/NEJMoa1215372 2671:Bernstein, J (2014). 1434:10.1056/NEJMra2120166 1214:Urticarial vasculitis 910: 893:post-traumatic stress 633:Further information: 615:Cholinergic urticaria 610:Cholinergic urticaria 604:Cholinergic or stress 342:urticarial vasculitis 331:cause remains unknown 307: 299: 291: 208:cause remains unknown 39:Hive (disambiguation) 5682:Autoimmune hepatitis 5661:Transplant rejection 5571:Giant cell arteritis 5501:Rheumatoid arthritis 5358:Goodpasture syndrome 5270:Autoimmune urticaria 5093:Generalized erythema 4900:Autoimmune urticaria 4895:Adrenergic urticaria 4850:Vibratory angioedema 4388:Annulare centrifugum 3911:Glucagonoma syndrome 3709:Basal-cell carcinoma 3684:Seborrheic keratosis 2683:(5): 1270–1277.e66. 2628:J Dtsch Dermatol Ges 2401:10.1067/mjd.2003.142 995:Vibratory angioedema 931:Acute versus chronic 800:rheumatoid arthritis 774:Autoimmune urticaria 482:species or possibly 204:Psychological stress 37:For other uses, see 5148:autoimmune diseases 5039:Erythema marginatum 4971:Erythema multiforme 4915:Schnitzler syndrome 4870:Aquagenic urticaria 4633:Aphthous stomatitis 4570:Lichen planopilaris 4545:Androgenic alopecia 4351:Fixed drug eruption 3926:Pemphigus foliaceus 3826:Granular cell tumor 3403:. London: Springer. 3291:10.12659/MSM.912362 2949:2013PLoSO...869345K 2510:(7): 2360–2369.e1. 853:variegate porphyria 672:Aquagenic urticaria 617:(CU) is one of the 485:Helicobacter pylori 468:. One study showed 429:. The antidiabetic 144:Based on symptoms, 87:Clinical immunology 5591:Reactive arthritis 5581:Multiple sclerosis 5475:Reactive arthritis 5373:Pemphigus vulgaris 5353:Bullous pemphigoid 5254:Penicillin allergy 5190:Allergic urticaria 4910:Galvanic urticaria 4905:Exercise urticaria 4855:Pressure urticaria 4775:Physical urticaria 4758:Allergic urticaria 4653:Pemphigus vulgaris 4482:Granuloma annulare 4346:Carcinoid syndrome 4231:Tuberous sclerosis 4190:Coccidioidomycosis 4064:Bullous pemphigoid 4059:Pemphigus vulgaris 3991:Secondary syphilis 3881:Contact dermatitis 3574:External resources 3493:2007-09-25 at the 3153:Kaplan AP (2009). 2622:Maurer, M (2013). 2589:J Am Acad Dermatol 1146:Opioid antagonists 974:Related conditions 916: 804:Sjögren's syndrome 730:interstitial fluid 619:physical urticaria 560:contact dermatitis 511:. You can help by 427:antidiabetic drugs 310: 302: 294: 284:Signs and symptoms 261:may also be used. 251:Immunosuppressants 18:Exercise urticaria 5721: 5720: 5717: 5716: 5622: 5621: 5514: 5513: 5423: 5422: 5419: 5418: 5411:Pernicious anemia 5406:Myasthenia gravis 5283: 5282: 5206:Atopic dermatitis 5195:Allergic rhinitis 5110: 5109: 5106: 5105: 5026:Figurate erythema 4956: 4955: 4878: 4877: 4700: 4699: 4696: 4695: 4540:Telogen effluvium 4504: 4503: 4500: 4499: 4461: 4460: 4457: 4456: 4402: 4401: 4254: 4253: 4122:Lichen spinulosus 4117:Keratosis pilaris 3996:Mycosis fungoides 3896:Stasis dermatitis 3886:Atopic dermatitis 3849: 3848: 3724:Trichoepithelioma 3699:Actinic keratosis 3619: 3618: 3470:Juhlin L. (2000) 3238:(10): 1224–1227. 3034:(10): 1607–1614. 2727:(Suppl 1): S1-5. 2641:10.1111/ddg.12194 2444:978-0-7216-2921-6 1676:10.1111/all.12818 1541:Skin Therapy Lett 1080:Systemic steroids 823:Nonallergic hives 529: 528: 474:alpha-gal allergy 387:dextroamphetamine 340:condition called 196:allergic reaction 177: 176: 140:Diagnostic method 117:allergic reaction 44:Medical condition 16:(Redirected from 5751: 5704:Sjögren syndrome 5633: 5535: 5440: 5336: 5315: 5175: 5144:Hypersensitivity 5137: 5130: 5123: 5114: 5078:Erythema toxicum 5044:Erythema migrans 5010:Erythema nodosum 4967: 4780: 4755: 4727: 4720: 4713: 4704: 4638:Oral candidiasis 4515: 4413: 4341:Erythema nodosum 4285: 4274: 4267: 4211:Tinea versicolor 4049:Bullous impetigo 3986:Pityriasis rosea 3921:Lichen sclerosus 3906:Darier's disease 3871: 3860: 3816:Kaposi's sarcoma 3662: 3646: 3639: 3632: 3623: 3599:search/Urticaria 3501: 3475: 3468: 3462: 3453: 3447: 3446: 3410: 3404: 3397: 3391: 3390: 3362: 3356: 3355: 3319: 3313: 3312: 3302: 3270: 3264: 3263: 3226: 3220: 3219: 3191: 3185: 3184: 3174: 3150: 3144: 3143: 3133: 3109: 3103: 3102: 3066: 3060: 3059: 3028:Clin Exp Allergy 3022: 3016: 3015: 2987: 2981: 2980: 2970: 2960: 2928: 2922: 2921: 2911: 2871: 2865: 2864: 2854: 2836: 2812: 2806: 2805: 2795: 2778:(11): CD006137. 2763: 2757: 2756: 2746: 2736: 2712: 2703: 2702: 2692: 2668: 2662: 2661: 2643: 2619: 2613: 2612: 2584: 2578: 2577: 2575: 2574: 2559: 2553: 2542: 2536: 2535: 2498: 2492: 2491: 2455: 2449: 2448: 2432: 2422: 2413: 2412: 2383: 2374: 2373: 2345: 2336: 2335: 2333: 2331: 2325: 2310: 2302: 2293: 2292: 2282: 2264: 2240: 2234: 2233: 2197: 2191: 2190: 2161: 2155: 2154: 2126: 2120: 2119: 2083: 2077: 2076: 2048: 2042: 2041: 2009: 2003: 2002: 2000: 1999: 1984: 1978: 1977: 1959: 1953: 1952: 1942: 1918: 1912: 1911: 1893: 1869: 1863: 1862: 1834: 1828: 1827: 1791: 1785: 1784: 1777: 1771: 1770: 1730: 1724: 1723: 1695: 1689: 1688: 1678: 1654: 1648: 1647: 1619: 1613: 1612: 1610: 1609: 1581: 1575: 1574: 1567: 1561: 1560: 1532: 1523: 1522: 1499: 1490: 1489: 1469: 1454: 1453: 1417: 1386: 1385: 1361: 1350: 1349: 1321: 1264: 1263: 1261: 1259: 1244: 964:dermatographisim 960: 959: 940: 939: 768:Autoimmune hives 537:strongyloidiasis 524: 521: 503: 496: 308:Drawing of hives 182:, also known as 72:Hives on the arm 67: 47: 21: 5759: 5758: 5754: 5753: 5752: 5750: 5749: 5748: 5724: 5723: 5722: 5713: 5665: 5628: 5618: 5600: 5596:Type 1 diabetes 5566:Coeliac disease 5554: 5526: 5510: 5484: 5450:Arthus reaction 5431: 5415: 5401:Graves' disease 5382: 5378:Rheumatic fever 5327: 5295: 5279: 5258: 5185:Allergic asthma 5166: 5150: 5141: 5111: 5102: 5088:Palmar erythema 5058: 5020: 4974: 4952: 4929: 4883:Other urticaria 4874: 4836: 4832:Solar urticaria 4813: 4769: 4742: 4734: 4731: 4701: 4692: 4624: 4617: 4584: 4550:Alopecia areata 4528: 4510: 4496: 4453: 4432: 4408: 4398: 4355: 4314: 4300:Viral exanthems 4278: 4262: 4260: 4250: 4221:Pityriasis alba 4199: 4141: 4083: 4020: 3940: 3936:Zinc deficiency 3866: 3864: 3845: 3773: 3764: 3728: 3719:Nevus sebaceous 3653: 3650: 3620: 3615: 3614: 3569: 3568: 3512: 3495:Wayback Machine 3484: 3479: 3478: 3469: 3465: 3454: 3450: 3412: 3411: 3407: 3398: 3394: 3364: 3363: 3359: 3321: 3320: 3316: 3272: 3271: 3267: 3228: 3227: 3223: 3193: 3192: 3188: 3152: 3151: 3147: 3111: 3110: 3106: 3068: 3067: 3063: 3024: 3023: 3019: 2989: 2988: 2984: 2930: 2929: 2925: 2886:(3): CD008596. 2873: 2872: 2868: 2814: 2813: 2809: 2765: 2764: 2760: 2714: 2713: 2706: 2670: 2669: 2665: 2634:(10): 971–978. 2621: 2620: 2616: 2586: 2585: 2581: 2572: 2570: 2561: 2560: 2556: 2543: 2539: 2500: 2499: 2495: 2457: 2456: 2452: 2445: 2424: 2423: 2416: 2385: 2384: 2377: 2347: 2346: 2339: 2329: 2327: 2323: 2313:Choosing Wisely 2308: 2304: 2303: 2296: 2242: 2241: 2237: 2199: 2198: 2194: 2163: 2162: 2158: 2128: 2127: 2123: 2085: 2084: 2080: 2050: 2049: 2045: 2011: 2010: 2006: 1997: 1995: 1986: 1985: 1981: 1974: 1961: 1960: 1956: 1920: 1919: 1915: 1871: 1870: 1866: 1836: 1835: 1831: 1793: 1792: 1788: 1779: 1778: 1774: 1732: 1731: 1727: 1697: 1696: 1692: 1656: 1655: 1651: 1621: 1620: 1616: 1607: 1605: 1598: 1583: 1582: 1578: 1569: 1568: 1564: 1534: 1533: 1526: 1515: 1501: 1500: 1493: 1486: 1471: 1470: 1457: 1419: 1418: 1389: 1378: 1363: 1362: 1353: 1323: 1322: 1267: 1257: 1255: 1246: 1245: 1232: 1227: 1210: 1185:Huangdi Neijing 1158: 1137: 1129: 1120: 1100: 1091: 1082: 1053:anticholinergic 1025:diphenhydramine 1006: 997: 981: 976: 957: 956: 937: 936: 933: 924:allergy testing 905: 889:quality of life 881: 871:This is termed 869: 861:solar urticaria 825: 816: 796:type 1 diabetes 776: 770: 749: 718: 712: 710:Pathophysiology 687: 674: 668: 660: 658:Solar urticaria 654: 652:Solar urticaria 637: 631: 612: 606: 597: 578: 572: 525: 519: 516: 509:needs expansion 494: 442: 411:anticonvulsants 375: 354: 321:from cutaneous 286: 243:corticosteroids 186:, is a kind of 160:corticosteroids 45: 42: 35: 28: 23: 22: 15: 12: 11: 5: 5757: 5755: 5747: 5746: 5741: 5736: 5726: 5725: 5719: 5718: 5715: 5714: 5712: 5711: 5706: 5701: 5700: 5699: 5694: 5684: 5679: 5673: 5671: 5667: 5666: 5664: 5663: 5658: 5652: 5651: 5650: 5639: 5637: 5630: 5624: 5623: 5620: 5619: 5617: 5616: 5610: 5608: 5602: 5601: 5599: 5598: 5593: 5588: 5583: 5578: 5573: 5568: 5562: 5560: 5556: 5555: 5553: 5552: 5547: 5541: 5539: 5532: 5516: 5515: 5512: 5511: 5509: 5508: 5503: 5498: 5492: 5490: 5486: 5485: 5483: 5482: 5480:Serum sickness 5477: 5472: 5467: 5462: 5457: 5452: 5446: 5444: 5437: 5434:Immune complex 5425: 5424: 5421: 5420: 5417: 5416: 5414: 5413: 5408: 5403: 5397: 5395: 5384: 5383: 5381: 5380: 5375: 5370: 5365: 5360: 5355: 5350: 5344: 5342: 5333: 5329: 5328: 5326: 5321: 5319: 5312: 5311: 5310: 5309: 5308: 5303: 5285: 5284: 5281: 5280: 5278: 5277: 5272: 5266: 5264: 5260: 5259: 5257: 5256: 5251: 5250: 5249: 5244: 5239: 5234: 5229: 5224: 5219: 5208: 5203: 5198: 5192: 5187: 5181: 5179: 5172: 5152: 5151: 5142: 5140: 5139: 5132: 5125: 5117: 5108: 5107: 5104: 5103: 5101: 5100: 5095: 5090: 5085: 5080: 5075: 5069: 5067: 5060: 5059: 5057: 5056: 5051: 5046: 5041: 5036: 5030: 5028: 5022: 5021: 5019: 5018: 5013: 5001: 4996: 4991: 4986: 4980: 4978: 4964: 4958: 4957: 4954: 4953: 4951: 4950: 4945: 4939: 4937: 4931: 4930: 4928: 4927: 4922: 4917: 4912: 4907: 4902: 4897: 4892: 4886: 4884: 4880: 4879: 4876: 4875: 4873: 4872: 4867: 4862: 4857: 4852: 4847: 4841: 4838: 4837: 4835: 4834: 4829: 4824: 4822:Heat urticaria 4818: 4815: 4814: 4812: 4811: 4806: 4801: 4796: 4795: 4794: 4787:Cold urticaria 4783: 4777: 4771: 4770: 4768: 4767: 4761: 4759: 4752: 4736: 4735: 4732: 4730: 4729: 4722: 4715: 4707: 4698: 4697: 4694: 4693: 4691: 4690: 4685: 4680: 4675: 4673:Coxsackievirus 4670: 4665: 4660: 4655: 4650: 4645: 4640: 4635: 4629: 4627: 4619: 4618: 4616: 4615: 4610: 4605: 4600: 4594: 4592: 4586: 4585: 4583: 4582: 4577: 4572: 4567: 4562: 4557: 4552: 4547: 4542: 4536: 4534: 4530: 4529: 4527: 4526: 4523: 4521: 4512: 4506: 4505: 4502: 4501: 4498: 4497: 4495: 4494: 4489: 4484: 4479: 4469: 4467: 4463: 4462: 4459: 4458: 4455: 4454: 4452: 4451: 4446: 4440: 4438: 4434: 4433: 4431: 4430: 4425: 4419: 4417: 4410: 4404: 4403: 4400: 4399: 4397: 4396: 4390: 4385: 4383:Gyratum repens 4380: 4375: 4369: 4363: 4361: 4357: 4356: 4354: 4353: 4348: 4343: 4338: 4333: 4328: 4322: 4320: 4316: 4315: 4313: 4312: 4307: 4305:Toxic erythema 4302: 4297: 4295:Drug eruptions 4291: 4289: 4282: 4271: 4264: 4256: 4255: 4252: 4251: 4249: 4248: 4243: 4238: 4233: 4228: 4223: 4218: 4213: 4207: 4205: 4201: 4200: 4198: 4197: 4192: 4187: 4182: 4177: 4172: 4167: 4162: 4157: 4151: 4149: 4143: 4142: 4140: 4139: 4134: 4132:Lichen nitidus 4129: 4124: 4119: 4114: 4109: 4104: 4099: 4093: 4091: 4085: 4084: 4082: 4081: 4076: 4071: 4066: 4061: 4056: 4051: 4046: 4041: 4036: 4034:Herpes simplex 4030: 4028: 4022: 4021: 4019: 4018: 4013: 4008: 4003: 3998: 3993: 3988: 3983: 3977: 3972: 3967: 3962: 3956: 3950: 3948: 3942: 3941: 3939: 3938: 3933: 3928: 3923: 3918: 3913: 3908: 3903: 3898: 3893: 3888: 3883: 3877: 3875: 3868: 3857: 3851: 3850: 3847: 3846: 3844: 3843: 3838: 3833: 3828: 3823: 3818: 3813: 3808: 3803: 3798: 3793: 3788: 3783: 3777: 3775: 3766: 3765: 3763: 3762: 3757: 3752: 3747: 3742: 3736: 3734: 3730: 3729: 3727: 3726: 3721: 3716: 3711: 3706: 3701: 3696: 3691: 3686: 3681: 3676: 3670: 3668: 3659: 3655: 3654: 3651: 3649: 3648: 3641: 3634: 3626: 3617: 3616: 3613: 3612: 3601: 3590: 3578: 3577: 3575: 3571: 3570: 3567: 3566: 3555: 3544: 3529: 3513: 3508: 3507: 3505: 3504:Classification 3498: 3497: 3483: 3482:External links 3480: 3477: 3476: 3463: 3448: 3405: 3392: 3357: 3314: 3265: 3232:Int J Dermatol 3221: 3186: 3165:(3): 713–717. 3145: 3124:(10): 924–35. 3104: 3061: 3017: 2998:(3): 484–488. 2982: 2923: 2866: 2807: 2758: 2704: 2663: 2614: 2595:(3): 387–391. 2579: 2565:. 2006-03-01. 2554: 2537: 2493: 2450: 2443: 2414: 2375: 2337: 2294: 2235: 2192: 2156: 2121: 2078: 2043: 2004: 1979: 1972: 1954: 1913: 1864: 1829: 1786: 1772: 1725: 1690: 1669:(3): 308–322. 1649: 1614: 1596: 1576: 1562: 1524: 1513: 1491: 1484: 1455: 1428:(9): 824–831. 1387: 1376: 1351: 1265: 1229: 1228: 1226: 1223: 1222: 1221: 1216: 1209: 1206: 1166:William Cullen 1157: 1154: 1136: 1133: 1128: 1125: 1119: 1116: 1099: 1096: 1090: 1087: 1081: 1078: 1005: 1002: 996: 993: 980: 977: 975: 972: 968: 967: 954: 932: 929: 904: 901: 880: 877: 868: 865: 833:immunoglobulin 824: 821: 815: 812: 792:celiac disease 772:Main article: 769: 766: 748: 747:Allergic hives 745: 711: 708: 686: 683: 670:Main article: 667: 664: 656:Main article: 653: 650: 635:Cold urticaria 630: 627: 608:Main article: 605: 602: 596: 593: 574:Main article: 571: 568: 539:among others. 533:blastocystosis 527: 526: 506: 504: 493: 490: 470:Balsam of Peru 441: 438: 405:, trichazole, 381:, sulphate of 374: 371: 353: 350: 285: 282: 227:antihistamines 175: 174: 171: 167: 166: 156:Antihistamines 153: 149: 148: 142: 136: 135: 126: 120: 119: 113: 109: 108: 105: 101: 100: 97: 91: 90: 80: 74: 73: 69: 68: 60: 59: 56: 52: 51: 43: 26: 24: 14: 13: 10: 9: 6: 4: 3: 2: 5756: 5745: 5742: 5740: 5737: 5735: 5732: 5731: 5729: 5710: 5707: 5705: 5702: 5698: 5695: 5693: 5690: 5689: 5688: 5685: 5683: 5680: 5678: 5675: 5674: 5672: 5668: 5662: 5659: 5656: 5655:Latex allergy 5653: 5649: 5646: 5645: 5644: 5641: 5640: 5638: 5634: 5631: 5625: 5615: 5612: 5611: 5609: 5607: 5603: 5597: 5594: 5592: 5589: 5587: 5584: 5582: 5579: 5577: 5574: 5572: 5569: 5567: 5564: 5563: 5561: 5557: 5551: 5548: 5546: 5543: 5542: 5540: 5536: 5533: 5530: 5525: 5524:cell-mediated 5521: 5517: 5507: 5504: 5502: 5499: 5497: 5494: 5493: 5491: 5487: 5481: 5478: 5476: 5473: 5471: 5468: 5466: 5463: 5461: 5458: 5456: 5455:Farmer's lung 5453: 5451: 5448: 5447: 5445: 5441: 5438: 5435: 5430: 5426: 5412: 5409: 5407: 5404: 5402: 5399: 5398: 5396: 5394: 5390: 5385: 5379: 5376: 5374: 5371: 5369: 5366: 5364: 5361: 5359: 5356: 5354: 5351: 5349: 5346: 5345: 5343: 5341: 5337: 5334: 5330: 5325: 5322: 5320: 5316: 5313: 5307: 5304: 5302: 5299: 5298: 5297: 5296: 5294: 5290: 5286: 5276: 5273: 5271: 5268: 5267: 5265: 5261: 5255: 5252: 5248: 5245: 5243: 5240: 5238: 5235: 5233: 5230: 5228: 5225: 5223: 5220: 5218: 5214: 5213: 5212: 5209: 5207: 5204: 5202: 5199: 5196: 5193: 5191: 5188: 5186: 5183: 5182: 5180: 5176: 5173: 5170: 5165: 5161: 5157: 5153: 5149: 5145: 5138: 5133: 5131: 5126: 5124: 5119: 5118: 5115: 5099: 5096: 5094: 5091: 5089: 5086: 5084: 5081: 5079: 5076: 5074: 5071: 5070: 5068: 5066: 5061: 5055: 5052: 5050: 5047: 5045: 5042: 5040: 5037: 5035: 5032: 5031: 5029: 5027: 5023: 5017: 5014: 5011: 5007: 5006: 5002: 5000: 4997: 4995: 4992: 4990: 4987: 4985: 4982: 4981: 4979: 4977: 4976:drug eruption 4972: 4968: 4965: 4963: 4959: 4949: 4946: 4944: 4941: 4940: 4938: 4936: 4932: 4926: 4923: 4921: 4918: 4916: 4913: 4911: 4908: 4906: 4903: 4901: 4898: 4896: 4893: 4891: 4888: 4887: 4885: 4881: 4871: 4868: 4866: 4863: 4861: 4858: 4856: 4853: 4851: 4848: 4846: 4843: 4842: 4839: 4833: 4830: 4828: 4825: 4823: 4820: 4819: 4816: 4810: 4807: 4805: 4802: 4800: 4797: 4793: 4790: 4789: 4788: 4785: 4784: 4781: 4778: 4776: 4772: 4766: 4763: 4762: 4760: 4756: 4753: 4750: 4746: 4741: 4737: 4728: 4723: 4721: 4716: 4714: 4709: 4708: 4705: 4689: 4686: 4684: 4681: 4679: 4676: 4674: 4671: 4669: 4666: 4664: 4661: 4659: 4656: 4654: 4651: 4649: 4646: 4644: 4643:Lichen planus 4641: 4639: 4636: 4634: 4631: 4630: 4628: 4626: 4620: 4614: 4611: 4609: 4606: 4604: 4601: 4599: 4598:Onychomycosis 4596: 4595: 4593: 4591: 4587: 4581: 4578: 4576: 4573: 4571: 4568: 4566: 4563: 4561: 4560:Tinea capitis 4558: 4556: 4553: 4551: 4548: 4546: 4543: 4541: 4538: 4537: 4535: 4531: 4525: 4524: 4522: 4520: 4516: 4513: 4509:Miscellaneous 4507: 4493: 4490: 4488: 4485: 4483: 4480: 4478: 4474: 4471: 4470: 4468: 4464: 4450: 4447: 4445: 4442: 4441: 4439: 4435: 4429: 4426: 4424: 4421: 4420: 4418: 4414: 4411: 4407:Nonblanchable 4405: 4394: 4391: 4389: 4386: 4384: 4381: 4379: 4376: 4374: 4370: 4368: 4365: 4364: 4362: 4358: 4352: 4349: 4347: 4344: 4342: 4339: 4337: 4334: 4332: 4329: 4327: 4324: 4323: 4321: 4317: 4311: 4308: 4306: 4303: 4301: 4298: 4296: 4293: 4292: 4290: 4286: 4283: 4281: 4275: 4272: 4268: 4265: 4257: 4247: 4244: 4242: 4239: 4237: 4234: 4232: 4229: 4227: 4224: 4222: 4219: 4217: 4214: 4212: 4209: 4208: 4206: 4204:Hypopigmented 4202: 4196: 4193: 4191: 4188: 4186: 4183: 4181: 4178: 4176: 4173: 4171: 4168: 4166: 4163: 4161: 4158: 4156: 4155:Acne vulgaris 4153: 4152: 4150: 4148: 4144: 4138: 4135: 4133: 4130: 4128: 4125: 4123: 4120: 4118: 4115: 4113: 4110: 4108: 4107:Lichen planus 4105: 4103: 4100: 4098: 4095: 4094: 4092: 4090: 4086: 4080: 4077: 4075: 4072: 4070: 4067: 4065: 4062: 4060: 4057: 4055: 4052: 4050: 4047: 4045: 4042: 4040: 4039:Herpes zoster 4037: 4035: 4032: 4031: 4029: 4027: 4023: 4017: 4014: 4012: 4011:Parapsoriasis 4009: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3984: 3981: 3978: 3976: 3973: 3971: 3968: 3966: 3963: 3961: 3957: 3955: 3952: 3951: 3949: 3947: 3943: 3937: 3934: 3932: 3929: 3927: 3924: 3922: 3919: 3917: 3914: 3912: 3909: 3907: 3904: 3902: 3899: 3897: 3894: 3892: 3889: 3887: 3884: 3882: 3879: 3878: 3876: 3872: 3869: 3861: 3858: 3856: 3852: 3842: 3839: 3837: 3834: 3832: 3829: 3827: 3824: 3822: 3819: 3817: 3814: 3812: 3809: 3807: 3804: 3802: 3799: 3797: 3794: 3792: 3789: 3787: 3784: 3782: 3779: 3778: 3776: 3771: 3767: 3761: 3758: 3756: 3753: 3751: 3748: 3746: 3743: 3741: 3738: 3737: 3735: 3731: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3705: 3702: 3700: 3697: 3695: 3692: 3690: 3687: 3685: 3682: 3680: 3677: 3675: 3672: 3671: 3669: 3667: 3663: 3660: 3656: 3647: 3642: 3640: 3635: 3633: 3628: 3627: 3624: 3611: 3607: 3606: 3602: 3600: 3596: 3595: 3591: 3589: 3585: 3584: 3580: 3579: 3576: 3572: 3565: 3561: 3560: 3556: 3554: 3550: 3549: 3545: 3543: 3539: 3538: 3534: 3530: 3528: 3524: 3523: 3519: 3515: 3514: 3511: 3506: 3502: 3496: 3492: 3489: 3486: 3485: 3481: 3473: 3467: 3464: 3460: 3459: 3452: 3449: 3444: 3440: 3436: 3432: 3428: 3424: 3420: 3416: 3409: 3406: 3402: 3396: 3393: 3388: 3384: 3380: 3376: 3372: 3368: 3361: 3358: 3353: 3349: 3345: 3341: 3337: 3333: 3329: 3325: 3318: 3315: 3310: 3306: 3301: 3296: 3292: 3288: 3284: 3280: 3276: 3269: 3266: 3261: 3257: 3253: 3249: 3245: 3241: 3237: 3233: 3225: 3222: 3217: 3213: 3209: 3205: 3201: 3197: 3196:Arch Dermatol 3190: 3187: 3182: 3178: 3173: 3168: 3164: 3160: 3156: 3149: 3146: 3141: 3137: 3132: 3127: 3123: 3119: 3115: 3108: 3105: 3100: 3096: 3092: 3088: 3084: 3080: 3076: 3072: 3065: 3062: 3057: 3053: 3049: 3045: 3041: 3037: 3033: 3029: 3021: 3018: 3013: 3009: 3005: 3001: 2997: 2993: 2986: 2983: 2978: 2974: 2969: 2964: 2959: 2954: 2950: 2946: 2943:(7): e69345. 2942: 2938: 2934: 2927: 2924: 2919: 2915: 2910: 2905: 2901: 2897: 2893: 2889: 2885: 2881: 2877: 2870: 2867: 2862: 2858: 2853: 2848: 2844: 2840: 2835: 2830: 2826: 2822: 2818: 2811: 2808: 2803: 2799: 2794: 2789: 2785: 2781: 2777: 2773: 2769: 2762: 2759: 2754: 2750: 2745: 2740: 2735: 2730: 2726: 2722: 2718: 2711: 2709: 2705: 2700: 2696: 2691: 2686: 2682: 2678: 2674: 2667: 2664: 2659: 2655: 2651: 2647: 2642: 2637: 2633: 2629: 2625: 2618: 2615: 2610: 2606: 2602: 2598: 2594: 2590: 2583: 2580: 2568: 2564: 2558: 2555: 2552: 2551: 2546: 2541: 2538: 2533: 2529: 2525: 2521: 2517: 2513: 2509: 2505: 2497: 2494: 2489: 2485: 2481: 2477: 2473: 2469: 2466:(8): 588–97. 2465: 2461: 2454: 2451: 2446: 2440: 2436: 2431: 2430: 2421: 2419: 2415: 2410: 2406: 2402: 2398: 2395:(3): 409–16. 2394: 2390: 2382: 2380: 2376: 2371: 2367: 2363: 2359: 2356:(3): 239–43. 2355: 2351: 2344: 2342: 2338: 2322: 2318: 2314: 2307: 2301: 2299: 2295: 2290: 2286: 2281: 2276: 2272: 2268: 2263: 2258: 2254: 2250: 2246: 2239: 2236: 2231: 2227: 2223: 2219: 2215: 2211: 2208:(4): 477–90. 2207: 2203: 2196: 2193: 2188: 2184: 2180: 2176: 2172: 2168: 2160: 2157: 2152: 2148: 2144: 2141:(4): 254–63. 2140: 2136: 2132: 2125: 2122: 2117: 2113: 2109: 2105: 2101: 2097: 2093: 2089: 2082: 2079: 2074: 2070: 2066: 2062: 2058: 2054: 2047: 2044: 2039: 2035: 2031: 2027: 2024:(3): 184–91. 2023: 2019: 2015: 2008: 2005: 1993: 1989: 1983: 1980: 1975: 1973:9780323088541 1969: 1965: 1958: 1955: 1950: 1946: 1941: 1936: 1933:(4): 539–44. 1932: 1928: 1924: 1917: 1914: 1909: 1905: 1901: 1897: 1892: 1887: 1883: 1879: 1875: 1868: 1865: 1860: 1856: 1852: 1848: 1844: 1840: 1833: 1830: 1825: 1821: 1817: 1813: 1809: 1805: 1802:(12): 794–9. 1801: 1797: 1790: 1787: 1782: 1776: 1773: 1768: 1764: 1760: 1756: 1752: 1748: 1745:(5): 504–13. 1744: 1740: 1736: 1729: 1726: 1721: 1717: 1713: 1709: 1705: 1701: 1694: 1691: 1686: 1682: 1677: 1672: 1668: 1664: 1660: 1653: 1650: 1645: 1641: 1637: 1633: 1629: 1625: 1618: 1615: 1603: 1599: 1597:9781550093780 1593: 1589: 1588: 1580: 1577: 1572: 1566: 1563: 1558: 1554: 1550: 1546: 1542: 1538: 1531: 1529: 1525: 1520: 1516: 1514:9781845935429 1510: 1506: 1505: 1498: 1496: 1492: 1487: 1485:9781118441176 1481: 1477: 1476: 1468: 1466: 1464: 1462: 1460: 1456: 1451: 1447: 1443: 1439: 1435: 1431: 1427: 1423: 1416: 1414: 1412: 1410: 1408: 1406: 1404: 1402: 1400: 1398: 1396: 1394: 1392: 1388: 1383: 1379: 1377:9783540790488 1373: 1369: 1368: 1360: 1358: 1356: 1352: 1347: 1343: 1339: 1335: 1332:(4): 473–83. 1331: 1327: 1320: 1318: 1316: 1314: 1312: 1310: 1308: 1306: 1304: 1302: 1300: 1298: 1296: 1294: 1292: 1290: 1288: 1286: 1284: 1282: 1280: 1278: 1276: 1274: 1272: 1270: 1266: 1253: 1249: 1243: 1241: 1239: 1237: 1235: 1231: 1224: 1220: 1217: 1215: 1212: 1211: 1207: 1205: 1203: 1199: 1195: 1191: 1187: 1186: 1181: 1177: 1176: 1175:Urtica dioica 1171: 1167: 1163: 1155: 1153: 1151: 1147: 1143: 1141: 1140:Afamelanotide 1134: 1132: 1126: 1124: 1117: 1115: 1111: 1108: 1104: 1097: 1095: 1088: 1086: 1079: 1077: 1075: 1071: 1069: 1065: 1061: 1056: 1054: 1050: 1049:desloratadine 1046: 1042: 1038: 1034: 1030: 1026: 1021: 1019: 1013: 1009: 1003: 1001: 994: 992: 990: 985: 978: 973: 971: 965: 955: 952: 947: 944: 935: 934: 930: 928: 925: 921: 920:Patch testing 913: 909: 902: 900: 898: 894: 890: 886: 878: 876: 874: 866: 864: 862: 858: 854: 850: 846: 842: 838: 837:neuropeptides 834: 830: 822: 820: 813: 811: 809: 805: 801: 797: 793: 789: 785: 781: 775: 767: 765: 762: 758: 754: 746: 744: 742: 738: 733: 731: 727: 723: 717: 709: 707: 704: 700: 695: 691: 684: 682: 680: 673: 666:Water-induced 665: 663: 659: 651: 649: 647: 641: 636: 628: 626: 623: 620: 616: 611: 603: 601: 594: 592: 588: 584: 582: 577: 569: 567: 565: 561: 557: 553: 549: 545: 540: 538: 534: 523: 514: 510: 507:This section 505: 502: 498: 497: 491: 489: 487: 486: 481: 480: 479:Streptococcus 475: 471: 467: 463: 459: 455: 451: 447: 439: 437: 435: 432: 431:sulphonylurea 428: 424: 420: 416: 412: 408: 404: 400: 396: 392: 388: 384: 380: 372: 370: 368: 364: 360: 351: 349: 347: 343: 338: 334: 332: 326: 324: 320: 315: 306: 298: 290: 283: 281: 279: 275: 272: 268: 262: 260: 256: 252: 248: 244: 240: 236: 232: 228: 223: 221: 220:Patch testing 217: 213: 209: 205: 201: 197: 192: 189: 185: 181: 172: 168: 165: 161: 157: 154: 150: 147: 146:patch testing 143: 141: 137: 134: 130: 127: 125: 121: 118: 114: 110: 106: 102: 98: 96: 92: 89:, Allergology 88: 84: 81: 79: 75: 70: 66: 61: 57: 53: 48: 40: 33: 19: 5550:Mantoux test 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Index

Exercise urticaria
HIV/AIDS
Hive (disambiguation)

Specialty
Dermatology
Clinical immunology
Symptoms
allergic reaction
Risk factors
Hay fever
asthma
Diagnostic method
patch testing
Antihistamines
corticosteroids
leukotriene inhibitors
skin rash
allergic reaction
insect bites
Psychological stress
cause remains unknown
hay fever
asthma
Patch testing
antihistamines
fexofenadine
loratadine
cetirizine
corticosteroids

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