297:
274:
171:
196:
303:
202:
1526:
50:
1472:
Glessner JT, Bradfield JP, Wang K, Takahashi N, Zhang H, Sleiman PM, Mentch FD, Kim CE, Hou C, Thomas KA, Garris ML, Deliard S, Frackelton EC, Otieno FG, Zhao J, Chiavacci RM, Li M, Buxbaum JD, Berkowitz RI, Hakonarson H, Grant SF (2010).
1036:
The protein encoded by this gene is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.
1215:
Niu JX, Zhang WJ, Ye LY, Wu LQ, Zhu GJ, Yang ZH, Grau GE, Lou JN (2007). "The role of adhesion molecules, alpha v beta 3, alpha v beta 5 and their ligands in the tumor cell and endothelial cell adhesion".
1186:
Aoka Y, Johnson FL, Penta K, Hirata Ki K, Hidai C, Schatzman R, Varner JA, Quertermous T (2002). "The embryonic angiogenic factor Del1 accelerates tumor growth by enhancing vascular formation".
1341:
Bozaoglu K, Curran JE, Stocker CJ, Zaibi MS, Segal D, Konstantopoulos N, Morrison S, Carless M, Dyer TD, Cole SA, Goring HH, Moses EK, Walder K, Cawthorne MA, Blangero J, Jowett JB (2010).
310:
209:
1583:
1157:
Rezaee M, Penta K, Quertermous T (2002). "Del1 mediates VSMC adhesion, migration, and proliferation through interaction with integrin alpha(v)beta(3)".
742:
723:
132:
1608:
1571:
1114:
1096:
1603:
296:
965:
958:
273:
1083:
1062:
1079:
195:
170:
47:
1058:
112:
309:
208:
302:
201:
1564:
1386:"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score"
787:
120:
768:
1298:
Johnson MP, Roten LT, Dyer TD, East CE, Forsmo S, Blangero J, Brennecke SP, Austgulen R, Moses EK (2009).
1255:"Downregulation of developmentally regulated endothelial cell locus-1 inhibits the growth of colon cancer"
1557:
184:
99:
937:
912:
882:
857:
1241:
144:
941:
916:
886:
861:
1504:
1460:
1415:
1372:
1329:
1286:
1233:
1203:
1174:
92:
40:
1541:
1494:
1486:
1450:
1440:
1405:
1397:
1362:
1354:
1319:
1311:
1276:
1266:
1225:
1195:
1166:
389:
320:
264:
219:
140:
364:
1300:"The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations"
1499:
1475:"A genome-wide study reveals copy number variants exclusive to childhood obesity cases"
1474:
1455:
1428:
1410:
1385:
1367:
1342:
1324:
1299:
1281:
1254:
657:
652:
647:
631:
626:
621:
616:
611:
595:
590:
585:
580:
1597:
1587:
567:
124:
1537:
1245:
382:
161:
1229:
148:
1427:
Sun JC, Liang XT, Pan K, Wang H, Zhao JJ, Li JJ, Ma HQ, Chen YB, Xia JC (2010).
1170:
1119:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1101:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1490:
1429:"High expression level of EDIL3 in HCC predicts poor prognosis of HCC patients"
465:
1401:
1315:
281:
178:
128:
1445:
1271:
687:
525:
403:
348:
335:
247:
234:
136:
1508:
1464:
1419:
1376:
1333:
1290:
1237:
1207:
1199:
1178:
1132:
1005:
1000:
1358:
989:
832:
813:
1021:
799:
754:
69:
973:
709:
1525:
672:
668:
1533:
1025:
116:
1343:"Chemerin, a novel adipokine in the regulation of angiogenesis"
372:
1545:
1253:
Zou X, Qiao H, Jiang X, Dong X, Jiang H, Sun X (2009).
1133:"Entrez Gene: EGF like repeats and discoidin domains 3"
1384:
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010).
537:
930:
905:
875:
850:
1075:
1073:
1071:
1054:
1052:
1050:
319:
218:
103:, DEL1, EGF like repeats and discoidin domains 3
16:Protein-coding gene in the species Homo sapiens
1080:GRCm38: Ensembl release 89: ENSMUSG00000034488
658:positive regulation of cell-substrate adhesion
1565:
8:
1059:GRCh38: Ensembl release 89: ENSG00000164176
596:extracellular matrix structural constituent
1584:United States National Library of Medicine
1572:
1558:
683:
563:
360:
259:
156:
58:
1498:
1454:
1444:
1409:
1366:
1323:
1280:
1270:
1582:This article incorporates text from the
1018:EGF like repeats and discoidin domains 3
632:collagen-containing extracellular matrix
1046:
1024:that in humans is encoded by the EDIL3
18:
324:
285:
280:
223:
182:
177:
7:
1522:
1520:
1159:Am. J. Physiol. Heart Circ. Physiol
1544:. You can help Knowledge (XXG) by
927:
902:
872:
847:
823:
804:
778:
759:
733:
714:
648:multicellular organism development
542:
460:
398:
377:
14:
446:lateral nuclear group of thalamus
1524:
418:inferior ganglion of vagus nerve
308:
301:
295:
272:
207:
200:
194:
169:
526:More reference expression data
1:
1609:Human chromosome 5 gene stubs
293:
192:
1230:10.1097/CEJ.0b013e3280145c00
488:anterior horn of spinal cord
1604:Genes on human chromosome 5
1171:10.1152/ajpheart.00921.2001
438:superior vestibular nucleus
1625:
1519:
1491:10.1016/j.ajhg.2010.09.014
1347:J. Clin. Endocrinol. Metab
476:lateral geniculate nucleus
1402:10.2119/molmed.2009.00159
1316:10.1007/s00439-009-0714-x
1115:"Mouse PubMed Reference:"
1097:"Human PubMed Reference:"
1004:
999:
995:
988:
972:
953:
934:
909:
898:
879:
854:
843:
830:
826:
811:
807:
798:
785:
781:
766:
762:
753:
740:
736:
721:
717:
708:
693:
686:
682:
666:
566:
562:
550:
545:
536:
523:
480:medial geniculate nucleus
472:
463:
410:
401:
371:
363:
359:
342:
329:
292:
271:
262:
258:
241:
228:
191:
168:
159:
155:
110:
107:
97:
90:
85:
66:
61:
44:
39:
34:
30:
26:
21:
1446:10.3748/wjg.v16.i36.4611
966:Chr 13: 88.97 – 89.47 Mb
414:external globus pallidus
1272:10.1186/1423-0127-16-33
959:Chr 5: 83.94 – 84.38 Mb
512:suprachiasmatic nucleus
1433:World J. Gastroenterol
1200:10.1006/mvre.2002.2414
1188:Microvascular Research
504:ventral tegmental area
500:deep cerebellar nuclei
450:ventral tegmental area
622:extracellular exosome
612:extracellular vesicle
484:medial dorsal nucleus
287:Chromosome 13 (mouse)
1359:10.1210/jc.2010-0042
627:extracellular matrix
617:extracellular region
508:lateral hypothalamus
185:Chromosome 5 (human)
62:List of PDB id codes
35:Available structures
1218:Eur. J. Cancer Prev
581:calcium ion binding
426:subthalamic nucleus
1586:, which is in the
1532:This article on a
788:ENSMUSG00000034488
641:Biological process
605:Cellular component
574:Molecular function
1553:
1552:
1479:Am. J. Hum. Genet
1015:
1014:
1011:
1010:
984:
983:
949:
948:
924:
923:
894:
893:
869:
868:
839:
838:
820:
819:
794:
793:
775:
774:
749:
748:
730:
729:
678:
677:
591:metal ion binding
558:
557:
554:
553:
532:
531:
519:
518:
457:
456:
355:
354:
254:
253:
149:EDIL3 - orthologs
81:
80:
77:
76:
45:Ortholog search:
1616:
1574:
1567:
1560:
1528:
1521:
1512:
1502:
1468:
1458:
1448:
1423:
1413:
1380:
1370:
1337:
1327:
1294:
1284:
1274:
1249:
1211:
1182:
1143:
1142:
1140:
1139:
1129:
1123:
1122:
1111:
1105:
1104:
1093:
1087:
1077:
1066:
1056:
997:
996:
968:
961:
944:
928:
919:
903:
899:RefSeq (protein)
889:
873:
864:
848:
824:
805:
779:
760:
734:
715:
684:
586:integrin binding
564:
543:
528:
468:
466:Top expressed in
461:
406:
404:Top expressed in
399:
378:
361:
351:
338:
327:
312:
305:
299:
288:
276:
260:
250:
237:
226:
211:
204:
198:
187:
173:
157:
151:
102:
95:
72:
59:
53:
32:
31:
19:
1624:
1623:
1619:
1618:
1617:
1615:
1614:
1613:
1594:
1593:
1579:
1578:
1517:
1515:
1471:
1426:
1396:(7–8): 247–53.
1383:
1340:
1297:
1252:
1214:
1185:
1165:(5): H1924–32.
1156:
1152:
1150:Further reading
1147:
1146:
1137:
1135:
1131:
1130:
1126:
1113:
1112:
1108:
1095:
1094:
1090:
1078:
1069:
1057:
1048:
1043:
1034:
1006:View/Edit Mouse
1001:View/Edit Human
964:
957:
954:Location (UCSC)
940:
936:
915:
911:
885:
881:
860:
856:
769:ENSG00000164176
662:
636:
600:
524:
515:
510:
506:
502:
498:
494:
492:globus pallidus
490:
486:
482:
478:
464:
453:
448:
444:
440:
436:
432:
428:
424:
422:pars reticulata
420:
416:
402:
346:
333:
325:
315:
314:
313:
306:
286:
263:Gene location (
245:
232:
224:
214:
213:
212:
205:
183:
160:Gene location (
111:
98:
91:
68:
46:
17:
12:
11:
5:
1622:
1620:
1612:
1611:
1606:
1596:
1595:
1577:
1576:
1569:
1562:
1554:
1551:
1550:
1529:
1514:
1513:
1469:
1439:(36): 4611–5.
1424:
1381:
1353:(5): 2476–85.
1338:
1295:
1259:J. Biomed. Sci
1250:
1212:
1183:
1153:
1151:
1148:
1145:
1144:
1124:
1106:
1088:
1067:
1045:
1044:
1042:
1039:
1033:
1030:
1013:
1012:
1009:
1008:
1003:
993:
992:
986:
985:
982:
981:
979:
977:
970:
969:
962:
955:
951:
950:
947:
946:
932:
931:
925:
922:
921:
907:
906:
900:
896:
895:
892:
891:
877:
876:
870:
867:
866:
852:
851:
845:
841:
840:
837:
836:
828:
827:
821:
818:
817:
809:
808:
802:
796:
795:
792:
791:
783:
782:
776:
773:
772:
764:
763:
757:
751:
750:
747:
746:
738:
737:
731:
728:
727:
719:
718:
712:
706:
705:
700:
695:
691:
690:
680:
679:
676:
675:
664:
663:
661:
660:
655:
650:
644:
642:
638:
637:
635:
634:
629:
624:
619:
614:
608:
606:
602:
601:
599:
598:
593:
588:
583:
577:
575:
571:
570:
560:
559:
556:
555:
552:
551:
548:
547:
540:
534:
533:
530:
529:
521:
520:
517:
516:
514:
513:
509:
505:
501:
497:
493:
489:
485:
481:
477:
473:
470:
469:
458:
455:
454:
452:
451:
447:
443:
439:
435:
431:
427:
423:
419:
415:
411:
408:
407:
395:
394:
386:
375:
369:
368:
365:RNA expression
357:
356:
353:
352:
344:
340:
339:
331:
328:
323:
317:
316:
307:
300:
294:
290:
289:
284:
278:
277:
269:
268:
256:
255:
252:
251:
243:
239:
238:
230:
227:
222:
216:
215:
206:
199:
193:
189:
188:
181:
175:
174:
166:
165:
153:
152:
109:
105:
104:
96:
88:
87:
83:
82:
79:
78:
75:
74:
64:
63:
55:
54:
43:
37:
36:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1621:
1610:
1607:
1605:
1602:
1601:
1599:
1592:
1591:
1589:
1588:public domain
1585:
1575:
1570:
1568:
1563:
1561:
1556:
1555:
1549:
1547:
1543:
1539:
1535:
1530:
1527:
1523:
1518:
1510:
1506:
1501:
1496:
1492:
1488:
1484:
1480:
1476:
1470:
1466:
1462:
1457:
1452:
1447:
1442:
1438:
1434:
1430:
1425:
1421:
1417:
1412:
1407:
1403:
1399:
1395:
1391:
1387:
1382:
1378:
1374:
1369:
1364:
1360:
1356:
1352:
1348:
1344:
1339:
1335:
1331:
1326:
1321:
1317:
1313:
1310:(5): 655–66.
1309:
1305:
1301:
1296:
1292:
1288:
1283:
1278:
1273:
1268:
1264:
1260:
1256:
1251:
1247:
1243:
1239:
1235:
1231:
1227:
1224:(6): 517–27.
1223:
1219:
1213:
1209:
1205:
1201:
1197:
1194:(1): 148–61.
1193:
1189:
1184:
1180:
1176:
1172:
1168:
1164:
1160:
1155:
1154:
1149:
1134:
1128:
1125:
1120:
1116:
1110:
1107:
1102:
1098:
1092:
1089:
1085:
1081:
1076:
1074:
1072:
1068:
1064:
1060:
1055:
1053:
1051:
1047:
1040:
1038:
1031:
1029:
1027:
1023:
1019:
1007:
1002:
998:
994:
991:
987:
980:
978:
975:
971:
967:
963:
960:
956:
952:
945:
943:
939:
933:
929:
926:
920:
918:
914:
908:
904:
901:
897:
890:
888:
884:
878:
874:
871:
865:
863:
859:
853:
849:
846:
844:RefSeq (mRNA)
842:
835:
834:
829:
825:
822:
816:
815:
810:
806:
803:
801:
797:
790:
789:
784:
780:
777:
771:
770:
765:
761:
758:
756:
752:
745:
744:
739:
735:
732:
726:
725:
720:
716:
713:
711:
707:
704:
701:
699:
696:
692:
689:
685:
681:
674:
670:
665:
659:
656:
654:
653:cell adhesion
651:
649:
646:
645:
643:
640:
639:
633:
630:
628:
625:
623:
620:
618:
615:
613:
610:
609:
607:
604:
603:
597:
594:
592:
589:
587:
584:
582:
579:
578:
576:
573:
572:
569:
568:Gene ontology
565:
561:
549:
544:
541:
539:
535:
527:
522:
511:
507:
503:
499:
495:
491:
487:
483:
479:
475:
474:
471:
467:
462:
459:
449:
445:
441:
437:
434:Pars compacta
433:
429:
425:
421:
417:
413:
412:
409:
405:
400:
397:
396:
393:
391:
387:
385:
384:
380:
379:
376:
374:
370:
366:
362:
358:
350:
345:
341:
337:
332:
326:13|13 C3
322:
318:
311:
304:
298:
291:
283:
279:
275:
270:
266:
261:
257:
249:
244:
240:
236:
231:
221:
217:
210:
203:
197:
190:
186:
180:
176:
172:
167:
163:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
114:
106:
101:
94:
89:
84:
73:
71:
65:
60:
57:
56:
52:
49:
42:
38:
33:
29:
25:
20:
1581:
1580:
1546:expanding it
1538:chromosome 5
1531:
1516:
1485:(5): 661–6.
1482:
1478:
1436:
1432:
1393:
1389:
1350:
1346:
1307:
1303:
1262:
1258:
1221:
1217:
1191:
1187:
1162:
1158:
1136:. Retrieved
1127:
1118:
1109:
1100:
1091:
1035:
1017:
1016:
938:NP_001033076
935:
913:NP_001265571
910:
883:NM_001037987
880:
858:NM_001278642
855:
831:
812:
786:
767:
741:
722:
702:
697:
388:
381:
108:External IDs
67:
347:89,471,342
334:88,969,591
246:84,384,880
233:83,940,554
86:Identifiers
1598:Categories
1304:Hum. Genet
1138:2017-07-24
1086:, May 2017
1065:, May 2017
1041:References
392:(ortholog)
129:HomoloGene
1536:on human
1265:(1): 33.
942:NP_034233
917:NP_005702
887:NM_010103
862:NM_005711
688:Orthologs
137:GeneCards
1509:20950786
1465:20857535
1420:20379614
1390:Mol. Med
1377:20237162
1334:19578876
1291:19292890
1238:18090124
1208:12074641
1179:11959660
1082:–
1061:–
1032:Function
990:Wikidata
667:Sources:
496:calvaria
1500:2978976
1456:2945496
1411:2896464
1368:2869547
1325:2783187
1282:2666667
1246:1825380
1084:Ensembl
1063:Ensembl
1022:protein
800:UniProt
755:Ensembl
694:Species
673:QuickGO
367:pattern
125:1329025
93:Aliases
1507:
1497:
1463:
1453:
1418:
1408:
1375:
1365:
1332:
1322:
1289:
1279:
1244:
1236:
1206:
1177:
976:search
974:PubMed
833:O35474
814:O43854
710:Entrez
538:BioGPS
225:5q14.3
117:606018
1540:is a
1242:S2CID
1020:is a
743:13612
724:10085
703:Mouse
698:Human
669:Amigo
430:tibia
390:Mouse
383:Human
330:Start
265:Mouse
229:Start
162:Human
141:EDIL3
133:21166
100:EDIL3
22:EDIL3
1542:stub
1534:gene
1505:PMID
1461:PMID
1416:PMID
1373:PMID
1330:PMID
1287:PMID
1234:PMID
1204:PMID
1175:PMID
1026:gene
442:pons
373:Bgee
321:Band
282:Chr.
220:Band
179:Chr.
113:OMIM
70:4D90
51:RCSB
48:PDBe
1495:PMC
1487:doi
1451:PMC
1441:doi
1406:PMC
1398:doi
1363:PMC
1355:doi
1320:PMC
1312:doi
1308:126
1277:PMC
1267:doi
1226:doi
1196:doi
1167:doi
1163:282
546:n/a
343:End
242:End
145:OMA
121:MGI
41:PDB
1600::
1503:.
1493:.
1483:87
1481:.
1477:.
1459:.
1449:.
1437:16
1435:.
1431:.
1414:.
1404:.
1394:16
1392:.
1388:.
1371:.
1361:.
1351:95
1349:.
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1220:.
1202:.
1192:64
1190:.
1173:.
1161:.
1117:.
1099:.
1070:^
1049:^
1028:.
671:/
349:bp
336:bp
248:bp
235:bp
143:;
139::
135:;
131::
127:;
123::
119:;
115::
1590:.
1573:e
1566:t
1559:v
1548:.
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1103:.
267:)
164:)
147::
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