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In the United States, efmoroctocog alfa (Eloctate) is indicated for adults and children with
Hemophilia A for (1) on-demand treatment and control of bleeding episodes, (2) perioperative management, and (3) routine prophylaxis to prevent or reduce the frequency of bleeding episodes.
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In the
European Union, efmoroctocog alfa (Elocta) is indicated for treatment and prophylaxis of bleeding in people with haemophilia A.
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787:
397:, Fc fusion protein (rFVIIIFc). It is produced by recombinant DNA technology in a human embryonic kidney (HEK) cell line.
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It was approved for medical use in the United States in June 2014, and for use in the
European Union in November 2015.
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539:"Elocta 1000 IU powder and solvent for solution for injection - Summary of Product Characteristics (SmPC)"
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among others, is a medication for the treatment and prophylaxis of bleeding in people with
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463:"Prescription medicines: registration of new chemical entities in Australia, 2014"
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578:"Eloctate (antihemophilic factor- recombinant, fc fusion protein kit"
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This article incorporates text from this source, which is in the
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393:. Efmoroctocog alfa is a recombinant human coagulation
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47:
Antihemophilic Factor (Recombinant), FcFusion
Protein
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651:"Efmoroctocog Alfa: A Review in Haemophilia A"
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1108:Tetragalacturonic acid hydroxymethylester
674:
281:
1319:Blood and blood forming organ drug stubs
699:"June 6, 2014 Approval Letter- Eloctate"
427:
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523:: CS1 maint: archived copy as title (
516:
467:Therapeutic Goods Administration (TGA)
437:Therapeutic Goods Administration (TGA)
20:
747:from the original on 29 November 2020
7:
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1234:
588:from the original on 29 October 2020
549:from the original on 28 October 2020
308:
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1262:. You can help Knowledge (XXG) by
630:from the original on 5 August 2020
505:from the original on 11 April 2023
473:from the original on 10 April 2023
443:from the original on 19 April 2023
14:
983:(II, VII, IX, X, protein C and S)
433:"AusPAR: Efmoroctocog alfa (rhu)"
1238:
1218:
757:
743:. 22 July 2017. STN: BL 125487.
342:
336:
1026:thrombopoietin receptor agonist
981:Prothrombin complex concentrate
1309:Drugs not assigned an ATC code
1118:Hemostatic Powder Spray TC-325
354:
348:
330:
1:
709:. 6 June 2014. Archived from
649:Frampton JE (November 2021).
739:Food and Drug Administration
705:Food and Drug Administration
385:, sold under the brand name
1335:
1233:
913:Valoctocogene roxaparvovec
667:10.1007/s40265-021-01615-w
320:Chemical and physical data
1074:Absorbable gelatin sponge
622:European Medicines Agency
1250:article relating to the
923:Fidanacogene elaparvovec
1157:Aminomethylbenzoic acid
889:Damoctocog alfa pegol
1314:Recombinant proteins
1256:blood forming organs
626:. 10 December 2015.
199:(Prescription only)
25:
16:Pharmaceutical drug
1103:Oxidized cellulose
893:Efanesoctocog alfa
1271:
1270:
1206:
1205:
1176:Alfa1 antitrypsin
1147:Aminocaproic acid
1132:Antifibrinolytics
1126:
1125:
1062:
1061:
897:Efmoroctocog alfa
847:Phytomenadione (K
661:(17): 2035–2046.
584:. 4 August 2020.
383:Efmoroctocog alfa
380:
379:
219:
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186: Unscheduled
185:
114:
81:
64:
23:Efmoroctocog alfa
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1079:Calcium alginate
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817:Antihemorrhagics
804:Antihemorrhagics
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469:. 21 June 2022.
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39:Elocta, Eloctate
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1152:Tranexamic acid
1122:
1058:
992:
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909:Turoctocog alfa
905:Susoctocog alfa
901:Moroctocog alfa
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713:on 23 July 2017
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145:Antihemorrhagic
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1052:Rafutrombopag
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1047:Lusutrombopag
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1005:Carbazochrome
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978:combinations:
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764:public domain
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617:"Elocta EPAR"
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29:Clinical data
27:
19:
1264:expanding it
1245:
1230:
1181:C1-inhibitor
1163:
1139:
1037:Avatrombopag
1024:
1020:Fostamatinib
977:
971:Catridecacog
962:I/Fibrinogen
948:
942:Eptacog alfa
934:
927:Nonacog alfa
896:
879:
856:Menadione (K
749:. Retrieved
736:
727:
715:. Retrieved
711:the original
702:
693:
658:
654:
644:
632:. Retrieved
620:
590:. Retrieved
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551:. Retrieved
542:
533:
507:. Retrieved
487:
475:. Retrieved
466:
457:
445:. Retrieved
436:
411:
407:
404:Medical uses
399:
391:hemophilia A
386:
382:
381:
243:1270012-79-7
173:Legal status
167:Legal status
53:License data
18:
1196:Ulinastatin
1141:amino acids
1098:Fibrin glue
1089:Epinephrine
1042:Eltrombopag
1032:Romiplostim
957:II/Thrombin
870:Coagulation
822:coagulation
751:3 September
717:3 September
634:3 September
592:3 September
553:3 September
395:factor VIII
376: g·mol
228:Identifiers
133:Intravenous
44:Other names
35:Trade names
1303:Categories
1093:adrenalone
1015:Etamsylate
1010:Concizumab
1000:Batroxobin
935:extrinsic:
880:intrinsic:
733:"Eloctate"
416:References
365:Molar mass
283:7PCM518YLR
234:CAS Number
140:Drug class
1192:unsorted
1171:Aprotinin
839:Vitamin K
126:Routes of
100:Pregnancy
1225:Medicine
1186:Camostat
1113:Thrombin
1084:Collagen
993:systemic
831:Systemic
745:Archived
685:34743314
628:Archived
586:Archived
582:DailyMed
547:Archived
519:cite web
509:11 April
500:Archived
477:10 April
471:Archived
447:28 April
441:Archived
254:DrugBank
152:ATC code
102:category
89:Eloctate
84:DailyMed
1165:serpins
949:common:
872:factors
676:8636404
326:Formula
263:DB11607
115: C
86::
69::
1211:Portal
683:
673:
387:Elocta
310:D10539
303:D10830
210:℞-only
208:
195:
82:
72:by INN
65:
1258:is a
1252:blood
1246:This
1067:Local
991:Other
741:(FDA)
737:U.S.
707:(FDA)
703:U.S.
655:Drugs
624:(EMA)
543:(emc)
503:(PDF)
496:(PDF)
340:14863
1260:stub
1254:and
1248:drug
967:XIII
885:VIII
753:2020
719:2020
681:PMID
636:2020
594:2020
555:2020
525:link
511:2023
479:2023
449:2023
352:2855
346:2591
334:9736
294:KEGG
274:UNII
159:None
938:VII
808:B02
671:PMC
663:doi
374:.96
372:390
370:216
197:POM
67:EMA
1305::
925:,
921:/(
919:IX
911:,
907:,
903:,
899:,
895:,
891:,
887:/(
735:.
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669:.
659:81
657:.
653:.
619:.
602:^
580:.
563:^
545:.
541:.
521:}}
517:{{
498:.
465:.
435:.
424:^
358:78
216:EU
204:US
191:UK
182:AU
111:AU
79:US
62:EU
1291:e
1284:t
1277:v
1266:.
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1091:/
969:/
952:X
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915:)
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858:3
851:)
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820:(
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806:(
796:e
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782:v
766:.
755:.
721:.
687:.
665::
638:.
596:.
557:.
527:)
513:.
481:.
451:.
355:S
349:O
343:N
337:H
331:C
218::
206::
193::
184::
113::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.