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204:, it acts as a wetting, stabilizing agent and a choline enrichment carrier, helps in emulsifications and encapsulation, and is a good dispersing agent. It can be used in manufacture of intravenous fat infusions and for therapeutic use. Examples of intravenous applications are
241:-derived lecithin is not usually a concern for those allergic to eggs since commercially available food grade egg lecithin is devoid of allergy causing egg proteins. Egg lecithin is not a concern for those on low-
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An example of a phosphatidylcholine, a type of phospholipid in egg lecithin. Red - choline and phosphate group; Black - glycerol; Green - unsaturated fatty acid; Blue - saturated fatty acid
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a major component of egg lecithin, occurs in all cellular organisms, being one of the important components of the phospholipid portion of the
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181:. It can be totally integrated into the cell membrane in humans, so does not need to be metabolized and is well tolerated by humans and non
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Parsaee, S; Sarbolouki, MN; Parnianpour, M (2002). "In-vitro release of diclofenac diethylammonium from lipid-based formulations".
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In the cosmetics industry, it is used to produce stable O/W emulsions for cosmetic compositions or pharmaceutical excipients
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Egg-derived phospholipids as an ingredient in term and preterm infant formula, Food and Drug
Administration, USA
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diets, because the lecithin found in eggs markedly inhibits the absorption of the cholesterol contained in eggs.
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due to restrictions on residual solvents by the pharmaceutical regulations. It is an emulsifier, especially for
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use since it does not need to be metabolized. In aqueous solution, its phospholipids can form either
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Gobley (1846) "Recherches chimiques sur le jaune d'œuf" (Chemical researches on egg yolk),
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145:(USP/NF) as used by pharmaceutical companies, is a highly purified mixture of
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structures, depending on hydration and temperature. This results in a type of
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Egg lecithin was first isolated in 1846 by the French chemist and pharmacist
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ICH Topic Q3C (R4) Impurities: Guideline for
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Why Eggs Don't
Contribute Much Cholesterol To Diet.
94:Egg lecithin is usually extracted chemically using
325:United States Patent No. 4481185, Grollier, et.al.
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51:. Gobley originally isolated lecithin from
141:Commercial egg lecithin, specified in the
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265:, series 3, vol. 9, pages 81-91; on
143:United States National Formulatory
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263:Journal de Pharmacie et de Chemie
219:Egg lecithin is approved by the
234:Compatibility with special diets
230:" and listed in the compendium.
185:when ingested; some synthetic
134:that is usually classified as
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304:10.1016/s0378-5173(02)00238-7
189:can only be excreted via the
39:, that is derived from eggs.
228:generally recognized as safe
224:Food and Drug Administration
165:Properties and applications
78:. Other components include
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403:Zwitterionic surfactants
373:Phosphatidylcholine info
363:Introduction to Lecithin
80:phosphatidylethanolamine
202:pharmaceutical industry
367:University of Erlangen
196:Applications include:
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177:properties, and is a
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212:, NSAID drugs, etc.
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59:) is 'egg yolk' in
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149:, devoid of
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25:Egg lecithin
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292:Int J Pharm
243:cholesterol
187:emulsifiers
155:cholesterol
136:amphipathic
387:Categories
249:References
210:anesthesia
179:surfactant
132:surfactant
116:parenteral
90:Production
175:lubricant
120:liposomes
43:Discovery
33:compounds
312:12086734
206:propofol
159:proteins
128:lamellar
124:micelles
106:but not
57:lekithos
53:egg yolk
29:lecithin
267:page 84
200:In the
191:kidneys
108:benzene
100:acetone
96:ethanol
67:Biology
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112:hexane
183:toxic
157:, or
126:, or
308:PMID
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