322:
299:
196:
221:
573:
328:
227:
1964:
37:
63:
1612:
Preproendothelin is precursor of the peptide ET-1. Endothelial cells convert preproendothelin to proendothelin and subsequently to mature endothelin, which the cells release.
335:
234:
1947:
1291:
1272:
157:
2038:
2033:
2009:
1855:
1732:
1714:
2028:
321:
1588:, as well as by cells in the heart (affecting contractility) and kidney (affecting sodium handling). The protein encoded by this gene –
1514:
1507:
712:
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
298:
1701:
1680:
1625:
1697:
220:
195:
60:
1676:
334:
233:
2002:
327:
226:
1336:
145:
1636:. Use of these antagonists prevents pulmonary arterial constriction and thus inhibits pulmonary hypertension.
1317:
1633:
1995:
209:
132:
1465:
1457:
1406:
1644:
169:
1490:
1469:
1461:
1431:
1410:
1924:
1902:
1851:
1828:
1811:
1788:
1757:
Davenport AP, Hyndman KA, Dhaun N, Southan C, Kohan DE, Pollock JS, et al. (April 2016).
1652:
125:
53:
1979:
1892:
1884:
1820:
1778:
1770:
1640:
1578:
572:
414:
345:
289:
244:
389:
165:
1897:
1872:
1783:
1758:
1206:
1201:
1196:
1191:
1186:
1181:
1176:
1171:
1166:
1161:
1156:
1151:
1146:
1141:
1136:
1131:
1126:
1121:
1116:
1111:
1106:
1101:
1096:
1091:
1086:
1081:
1076:
1071:
1066:
1061:
1056:
1051:
1046:
1041:
1036:
1031:
1026:
1021:
1016:
1011:
1006:
1001:
996:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
791:
786:
781:
776:
771:
766:
761:
756:
751:
746:
741:
736:
731:
726:
721:
716:
711:
706:
701:
685:
680:
675:
670:
665:
660:
655:
639:
634:
629:
624:
619:
614:
2022:
1951:
1933:
601:
1975:
1621:
407:
186:
1809:
Jankowich M, Choudhary G (2020). "Endothelin-1 levels and cardiovascular events".
149:
173:
1737:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1719:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1593:
1585:
490:
1824:
1601:
1167:
positive regulation of cell growth involved in cardiac muscle cell development
306:
203:
153:
1236:
550:
428:
373:
360:
272:
259:
161:
17:
1906:
1832:
1792:
1207:
positive regulation of vascular associated smooth muscle cell proliferation
1774:
1554:
1549:
36:
1629:
1538:
1381:
1362:
1187:
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
862:
protein kinase C-activating G protein-coupled receptor signaling pathway
1938:
1928:
1873:"Endothelin-1 in the pathophysiology of obesity and insulin resistance"
1648:
1597:
1581:
1348:
1303:
992:
phospholipase D-activating G protein-coupled receptor signaling pathway
1888:
102:
98:
94:
90:
86:
82:
1522:
1258:
1963:
1871:
Jenkins HN, Rivera-Gonzalez O, Gibert Y, Speed JS (December 2020).
892:
positive regulation of prostaglandin-endoperoxide synthase activity
1596:
processed to release endothelin 1. Endothelin 1 is one of three
1221:
1217:
887:
negative regulation of nitric-oxide synthase biosynthetic process
1971:
1162:
positive regulation of DNA-binding transcription factor activity
581:
802:
cellular response to transforming growth factor beta stimulus
1923:
Overview of all the structural information available in the
1042:
regulation of systemic arterial blood pressure by endothelin
1142:
negative regulation of smooth muscle cell apoptotic process
767:
positive regulation of chemokine-mediated signaling pathway
1062:
positive regulation of cytosolic calcium ion concentration
1157:
positive regulation of transcription by RNA polymerase II
917:
negative regulation of transcription by RNA polymerase II
1072:
positive regulation of nitric oxide biosynthetic process
397:
1983:
1007:
positive regulation of smooth muscle cell proliferation
1848:
Medical physiology: a cellular and molecular approach
562:
1127:
positive regulation of cell population proliferation
1483:
1450:
1424:
1399:
1693:
1691:
1689:
1672:
1670:
1668:
1639:As of 2020, the role of endothelin-1 in affecting
927:respiratory gaseous exchange by respiratory system
1102:positive regulation of endothelial cell migration
742:positive regulation of cardiac muscle hypertrophy
344:
243:
882:positive regulation of smooth muscle contraction
872:branching involved in blood vessel morphogenesis
1122:cellular response to mineralocorticoid stimulus
782:positive regulation of mitotic nuclear division
136:, ARCND3, ET1, HDLCQ7, QME, endothelin 1, PPET1
1804:
1802:
1698:GRCm38: Ensembl release 89: ENSMUSG00000021367
1202:positive regulation of NIK/NF-kappaB signaling
842:positive regulation of prostaglandin secretion
2003:
1192:regulation of glucose transmembrane transport
1107:cellular response to peptide hormone stimulus
807:positive regulation of renal sodium excretion
737:positive regulation of sarcomere organization
8:
1182:G protein-coupled receptor signaling pathway
1172:positive regulation of neutrophil chemotaxis
867:cellular response to glucocorticoid stimulus
1677:GRCh38: Ensembl release 89: ENSG00000078401
1152:response to transforming growth factor beta
2010:
1996:
1948:United States National Library of Medicine
1232:
1082:cellular response to tumor necrosis factor
902:positive regulation of JUN kinase activity
717:positive regulation of MAP kinase activity
597:
385:
284:
181:
71:
1896:
1782:
1177:regulation of signaling receptor activity
1946:This article incorporates text from the
1137:positive regulation of hormone secretion
1022:maternal process involved in parturition
877:negative regulation of hormone secretion
817:negative regulation of blood coagulation
722:regulation of sensory perception of pain
1664:
772:phosphatidylinositol 3-kinase signaling
747:cell surface receptor signaling pathway
1197:negative regulation of gene expression
26:
1752:
1750:
1748:
1746:
1132:inositol phosphate-mediated signaling
1052:positive regulation of cell migration
762:cellular response to interferon-gamma
349:
310:
305:
248:
207:
202:
7:
1960:
1958:
997:positive regulation of odontogenesis
521:endothelial cell of lymphatic vessel
897:positive regulation of urine volume
1982:. You can help Knowledge (XXG) by
1480:
1447:
1421:
1396:
1372:
1353:
1327:
1308:
1282:
1263:
982:prostaglandin biosynthetic process
957:cellular response to interleukin-1
567:
485:
423:
402:
25:
1812:Trends in Cardiovascular Medicine
1626:Endothelin-1 receptor antagonists
1027:intracellular signal transduction
932:positive regulation of heart rate
676:rough endoplasmic reticulum lumen
1962:
987:dorsal/ventral pattern formation
967:positive regulation of cell size
797:cellular response to calcium ion
757:artery smooth muscle contraction
571:
333:
326:
320:
297:
232:
225:
219:
194:
35:
1632:) are used in the treatment of
1112:cellular response to fatty acid
1846:Boulpaep EL, Boron WF (2009).
952:regulation of vasoconstriction
942:response to lipopolysaccharide
847:vein smooth muscle contraction
827:in utero embryonic development
582:More reference expression data
551:More reference expression data
1:
2039:Human chromosome 6 gene stubs
1620:Patients with salt-sensitive
1037:neural crest cell development
1012:protein kinase C deactivation
640:endothelin A receptor binding
630:endothelin B receptor binding
318:
217:
2034:Endothelin receptor agonists
937:regulation of blood pressure
787:cellular response to hypoxia
752:multicellular organism aging
2029:Genes on human chromosome 6
1097:superoxide anion generation
947:response to prostaglandin F
702:skeletal system development
451:subcutaneous adipose tissue
2055:
1957:
1624:have higher plasma ET-1.
1147:calcium-mediated signaling
1067:epithelial fluid transport
977:sensory perception of pain
812:blood vessel morphogenesis
792:response to muscle stretch
620:signaling receptor binding
1825:10.1016/j.tcm.2019.01.007
1733:"Mouse PubMed Reference:"
1715:"Human PubMed Reference:"
1553:
1548:
1544:
1537:
1521:
1502:
1487:
1454:
1443:
1428:
1403:
1392:
1379:
1375:
1360:
1356:
1347:
1334:
1330:
1315:
1311:
1302:
1289:
1285:
1270:
1266:
1257:
1242:
1235:
1231:
1215:
1117:peptide hormone secretion
1092:response to dexamethasone
600:
596:
579:
570:
561:
548:
497:
488:
435:
426:
396:
388:
384:
367:
354:
317:
296:
287:
283:
266:
253:
216:
193:
184:
180:
143:
140:
130:
123:
118:
79:
74:
57:
52:
47:
43:
34:
29:
1515:Chr 13: 42.45 – 42.46 Mb
1057:response to testosterone
972:middle ear morphogenesis
1763:Pharmacological Reviews
912:membrane depolarization
537:external carotid artery
455:upper lobe of left lung
1937:(Endothelin-1) at the
1634:pulmonary hypertension
1508:Chr 6: 12.29 – 12.3 Mb
1047:nitric oxide transport
707:response to amino acid
351:13 A4|13 20.82 cM
1850:. Saunders/Elsevier.
1775:10.1124/pr.115.011833
1651:mechanisms was under
1616:Clinical significance
1584:produced by vascular
1577:(PPET1), is a potent
852:cartilage development
832:neutrophil chemotaxis
312:Chromosome 13 (mouse)
1087:response to activity
907:leukocyte activation
822:response to nicotine
732:body fluid secretion
671:extracellular region
529:vascular endothelium
505:vasculature of trunk
210:Chromosome 6 (human)
75:List of PDB id codes
48:Available structures
1077:cell-cell signaling
1032:response to hypoxia
1017:histamine secretion
857:rhythmic excitation
681:extracellular space
467:islet of Langerhans
1970:This article on a
1950:, which is in the
1645:insulin resistance
1575:preproendothelin-1
1337:ENSMUSG00000021367
777:response to leptin
695:Biological process
666:basal part of cell
661:Weibel-Palade body
649:Cellular component
608:Molecular function
443:buccal mucosa cell
439:lower lobe of lung
1991:
1990:
1889:10.1111/obr.13086
1857:978-1-4160-3115-4
1653:clinical research
1586:endothelial cells
1573:), also known as
1564:
1563:
1560:
1559:
1533:
1532:
1498:
1497:
1477:
1476:
1439:
1438:
1418:
1417:
1388:
1387:
1369:
1368:
1343:
1342:
1324:
1323:
1298:
1297:
1279:
1278:
1227:
1226:
922:response to ozone
837:heart development
686:transport vesicle
625:cytokine activity
592:
591:
588:
587:
557:
556:
544:
543:
482:
481:
380:
379:
279:
278:
114:
113:
110:
109:
58:Ortholog search:
16:(Redirected from
2046:
2012:
2005:
1998:
1966:
1959:
1911:
1910:
1900:
1868:
1862:
1861:
1843:
1837:
1836:
1806:
1797:
1796:
1786:
1754:
1741:
1740:
1729:
1723:
1722:
1711:
1705:
1695:
1684:
1674:
1641:lipid metabolism
1546:
1545:
1517:
1510:
1493:
1481:
1472:
1448:
1444:RefSeq (protein)
1434:
1422:
1413:
1397:
1373:
1354:
1328:
1309:
1283:
1264:
1233:
1002:regulation of pH
962:response to salt
727:vasoconstriction
615:hormone activity
598:
584:
575:
568:
553:
493:
491:Top expressed in
486:
431:
429:Top expressed in
424:
403:
386:
376:
363:
352:
337:
330:
324:
313:
301:
285:
275:
262:
251:
236:
229:
223:
212:
198:
182:
176:
174:EDN1 - orthologs
135:
128:
105:
72:
66:
45:
44:
39:
27:
21:
2054:
2053:
2049:
2048:
2047:
2045:
2044:
2043:
2019:
2018:
2017:
2016:
1920:
1915:
1914:
1877:Obesity Reviews
1870:
1869:
1865:
1858:
1845:
1844:
1840:
1808:
1807:
1800:
1756:
1755:
1744:
1731:
1730:
1726:
1713:
1712:
1708:
1696:
1687:
1675:
1666:
1661:
1618:
1610:
1594:proteolytically
1579:vasoconstrictor
1555:View/Edit Mouse
1550:View/Edit Human
1513:
1506:
1503:Location (UCSC)
1489:
1468:
1464:
1460:
1456:
1430:
1409:
1405:
1318:ENSG00000078401
1211:
690:
644:
635:protein binding
580:
549:
540:
535:
531:
527:
523:
519:
515:
513:right lung lobe
511:
507:
503:
489:
478:
473:
469:
465:
461:
457:
453:
449:
445:
441:
427:
371:
358:
350:
340:
339:
338:
331:
311:
288:Gene location (
270:
257:
249:
239:
238:
237:
230:
208:
185:Gene location (
144:
131:
124:
81:
59:
23:
22:
15:
12:
11:
5:
2052:
2050:
2042:
2041:
2036:
2031:
2021:
2020:
2015:
2014:
2007:
2000:
1992:
1989:
1988:
1967:
1943:
1942:
1919:
1918:External links
1916:
1913:
1912:
1883:(12): e13086.
1863:
1856:
1838:
1798:
1769:(2): 357–418.
1742:
1724:
1706:
1685:
1663:
1662:
1660:
1657:
1617:
1614:
1609:
1606:
1562:
1561:
1558:
1557:
1552:
1542:
1541:
1535:
1534:
1531:
1530:
1528:
1526:
1519:
1518:
1511:
1504:
1500:
1499:
1496:
1495:
1485:
1484:
1478:
1475:
1474:
1452:
1451:
1445:
1441:
1440:
1437:
1436:
1426:
1425:
1419:
1416:
1415:
1401:
1400:
1394:
1390:
1389:
1386:
1385:
1377:
1376:
1370:
1367:
1366:
1358:
1357:
1351:
1345:
1344:
1341:
1340:
1332:
1331:
1325:
1322:
1321:
1313:
1312:
1306:
1300:
1299:
1296:
1295:
1287:
1286:
1280:
1277:
1276:
1268:
1267:
1261:
1255:
1254:
1249:
1244:
1240:
1239:
1229:
1228:
1225:
1224:
1213:
1212:
1210:
1209:
1204:
1199:
1194:
1189:
1184:
1179:
1174:
1169:
1164:
1159:
1154:
1149:
1144:
1139:
1134:
1129:
1124:
1119:
1114:
1109:
1104:
1099:
1094:
1089:
1084:
1079:
1074:
1069:
1064:
1059:
1054:
1049:
1044:
1039:
1034:
1029:
1024:
1019:
1014:
1009:
1004:
999:
994:
989:
984:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
784:
779:
774:
769:
764:
759:
754:
749:
744:
739:
734:
729:
724:
719:
714:
709:
704:
698:
696:
692:
691:
689:
688:
683:
678:
673:
668:
663:
658:
652:
650:
646:
645:
643:
642:
637:
632:
627:
622:
617:
611:
609:
605:
604:
594:
593:
590:
589:
586:
585:
577:
576:
565:
559:
558:
555:
554:
546:
545:
542:
541:
539:
538:
534:
533:left lung lobe
530:
526:
522:
518:
514:
510:
506:
502:
498:
495:
494:
483:
480:
479:
477:
476:
472:
468:
464:
460:
456:
452:
448:
444:
440:
436:
433:
432:
420:
419:
411:
400:
394:
393:
390:RNA expression
382:
381:
378:
377:
369:
365:
364:
356:
353:
348:
342:
341:
332:
325:
319:
315:
314:
309:
303:
302:
294:
293:
281:
280:
277:
276:
268:
264:
263:
255:
252:
247:
241:
240:
231:
224:
218:
214:
213:
206:
200:
199:
191:
190:
178:
177:
142:
138:
137:
129:
121:
120:
116:
115:
112:
111:
108:
107:
77:
76:
68:
67:
56:
50:
49:
41:
40:
32:
31:
24:
14:
13:
10:
9:
6:
4:
3:
2:
2051:
2040:
2037:
2035:
2032:
2030:
2027:
2026:
2024:
2013:
2008:
2006:
2001:
1999:
1994:
1993:
1987:
1985:
1981:
1977:
1973:
1968:
1965:
1961:
1956:
1955:
1953:
1952:public domain
1949:
1940:
1936:
1935:
1930:
1926:
1922:
1921:
1917:
1908:
1904:
1899:
1894:
1890:
1886:
1882:
1878:
1874:
1867:
1864:
1859:
1853:
1849:
1842:
1839:
1834:
1830:
1826:
1822:
1818:
1814:
1813:
1805:
1803:
1799:
1794:
1790:
1785:
1780:
1776:
1772:
1768:
1764:
1760:
1753:
1751:
1749:
1747:
1743:
1738:
1734:
1728:
1725:
1720:
1716:
1710:
1707:
1703:
1699:
1694:
1692:
1690:
1686:
1682:
1678:
1673:
1671:
1669:
1665:
1658:
1656:
1654:
1650:
1646:
1642:
1637:
1635:
1631:
1627:
1623:
1615:
1613:
1607:
1605:
1603:
1599:
1595:
1591:
1587:
1583:
1580:
1576:
1572:
1568:
1556:
1551:
1547:
1543:
1540:
1536:
1529:
1527:
1524:
1520:
1516:
1512:
1509:
1505:
1501:
1494:
1492:
1486:
1482:
1479:
1473:
1471:
1467:
1463:
1459:
1453:
1449:
1446:
1442:
1435:
1433:
1427:
1423:
1420:
1414:
1412:
1408:
1402:
1398:
1395:
1393:RefSeq (mRNA)
1391:
1384:
1383:
1378:
1374:
1371:
1365:
1364:
1359:
1355:
1352:
1350:
1346:
1339:
1338:
1333:
1329:
1326:
1320:
1319:
1314:
1310:
1307:
1305:
1301:
1294:
1293:
1288:
1284:
1281:
1275:
1274:
1269:
1265:
1262:
1260:
1256:
1253:
1250:
1248:
1245:
1241:
1238:
1234:
1230:
1223:
1219:
1214:
1208:
1205:
1203:
1200:
1198:
1195:
1193:
1190:
1188:
1185:
1183:
1180:
1178:
1175:
1173:
1170:
1168:
1165:
1163:
1160:
1158:
1155:
1153:
1150:
1148:
1145:
1143:
1140:
1138:
1135:
1133:
1130:
1128:
1125:
1123:
1120:
1118:
1115:
1113:
1110:
1108:
1105:
1103:
1100:
1098:
1095:
1093:
1090:
1088:
1085:
1083:
1080:
1078:
1075:
1073:
1070:
1068:
1065:
1063:
1060:
1058:
1055:
1053:
1050:
1048:
1045:
1043:
1040:
1038:
1035:
1033:
1030:
1028:
1025:
1023:
1020:
1018:
1015:
1013:
1010:
1008:
1005:
1003:
1000:
998:
995:
993:
990:
988:
985:
983:
980:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
948:
945:
943:
940:
938:
935:
933:
930:
928:
925:
923:
920:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
820:
818:
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
788:
785:
783:
780:
778:
775:
773:
770:
768:
765:
763:
760:
758:
755:
753:
750:
748:
745:
743:
740:
738:
735:
733:
730:
728:
725:
723:
720:
718:
715:
713:
710:
708:
705:
703:
700:
699:
697:
694:
693:
687:
684:
682:
679:
677:
674:
672:
669:
667:
664:
662:
659:
657:
654:
653:
651:
648:
647:
641:
638:
636:
633:
631:
628:
626:
623:
621:
618:
616:
613:
612:
610:
607:
606:
603:
602:Gene ontology
599:
595:
583:
578:
574:
569:
566:
564:
560:
552:
547:
536:
532:
528:
524:
520:
516:
512:
509:Aortic arches
508:
504:
500:
499:
496:
492:
487:
484:
474:
470:
466:
462:
458:
454:
450:
446:
442:
438:
437:
434:
430:
425:
422:
421:
418:
416:
412:
410:
409:
405:
404:
401:
399:
395:
391:
387:
383:
375:
370:
366:
362:
357:
347:
343:
336:
329:
323:
316:
308:
304:
300:
295:
291:
286:
282:
274:
269:
265:
261:
256:
246:
242:
235:
228:
222:
215:
211:
205:
201:
197:
192:
188:
183:
179:
175:
171:
167:
163:
159:
155:
151:
147:
139:
134:
127:
122:
117:
106:
104:
100:
96:
92:
88:
84:
78:
73:
70:
69:
65:
62:
55:
51:
46:
42:
38:
33:
28:
19:
1984:expanding it
1976:chromosome 6
1969:
1945:
1944:
1932:
1880:
1876:
1866:
1847:
1841:
1816:
1810:
1766:
1762:
1759:"Endothelin"
1736:
1727:
1718:
1709:
1638:
1622:hypertension
1619:
1611:
1589:
1574:
1570:
1567:Endothelin 1
1566:
1565:
1488:
1466:NP_001161791
1458:NP_001161791
1455:
1429:
1407:NM_001168319
1404:
1380:
1361:
1335:
1316:
1290:
1271:
1251:
1246:
517:dorsal aorta
471:tibial nerve
413:
406:
141:External IDs
80:
18:Endothelin-1
463:human penis
459:skin of hip
372:42,461,466
359:42,454,952
271:12,297,194
258:12,290,361
119:Identifiers
2023:Categories
1819:(1): 1–8.
1704:, May 2017
1683:, May 2017
1659:References
1602:endothelin
525:left colon
447:right lung
417:(ortholog)
154:HomoloGene
1974:on human
1600:of human
1491:NP_034234
1470:NP_001946
1462:NP_001946
1432:NM_010104
1411:NM_001955
1237:Orthologs
656:cytoplasm
162:GeneCards
1907:32627269
1833:30765295
1793:26956245
1700:–
1679:–
1630:Bosentan
1598:isoforms
1539:Wikidata
1216:Sources:
1939:PDBe-KB
1929:UniProt
1898:7669671
1784:4815360
1702:Ensembl
1681:Ensembl
1649:obesity
1608:Sources
1582:peptide
1349:UniProt
1304:Ensembl
1243:Species
1222:QuickGO
501:pharynx
392:pattern
126:Aliases
1934:P05305
1905:
1895:
1854:
1831:
1791:
1781:
1525:search
1523:PubMed
1382:P22387
1363:P05305
1259:Entrez
563:BioGPS
475:rectum
250:6p24.1
1978:is a
1592:– is
1292:13614
1252:Mouse
1247:Human
1218:Amigo
415:Mouse
408:Human
355:Start
290:Mouse
254:Start
187:Human
150:95283
1980:stub
1972:gene
1927:for
1903:PMID
1852:ISBN
1829:PMID
1789:PMID
1643:and
1590:EDN1
1571:ET-1
1273:1906
398:Bgee
346:Band
307:Chr.
245:Band
204:Chr.
166:EDN1
158:1476
133:EDN1
103:5GLH
99:6DK5
95:1V6R
91:1T7H
87:1EDP
83:1EDN
64:RCSB
61:PDBe
30:EDN1
1925:PDB
1893:PMC
1885:doi
1821:doi
1779:PMC
1771:doi
1647:in
368:End
267:End
170:OMA
146:MGI
54:PDB
2025::
1931::
1901:.
1891:.
1881:21
1879:.
1875:.
1827:.
1817:30
1815:.
1801:^
1787:.
1777:.
1767:68
1765:.
1761:.
1745:^
1735:.
1717:.
1688:^
1667:^
1655:.
1604:.
1220:/
374:bp
361:bp
273:bp
260:bp
168:;
164::
160:;
156::
152:;
148::
101:,
97:,
93:,
89:,
85:,
2011:e
2004:t
1997:v
1986:.
1954:.
1941:.
1909:.
1887::
1860:.
1835:.
1823::
1795:.
1773::
1739:.
1721:.
1628:(
1569:(
292:)
189:)
172::
20:)
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
