328:
305:
202:
227:
2399:
579:
586:
2369:
334:
233:
2384:
31:
5645:
1265:. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the
1480:
Rotondo JC, Bosi S, Bassi C, Ferracin M, Lanza G, Gafà R, Magri E, Selvatici R, Torresani S, Marci R, Garutti P, Negrini M, Tognon M, Martini F (April 2015). "Gene expression changes in progression of cervical neoplasia revealed by microarray analysis of cervical neoplastic keratinocytes".
57:
2169:
Vogt T, Stolz W, Welsh J, Jung B, Kerbel RS, Kobayashi H, Landthaler M, McClelland M (Mar 1998). "Overexpression of Lerk-5/Eplg5 messenger RNA: a novel marker for increased tumorigenicity and metastatic potential in human malignant melanomas".
2226:
Nikolova Z, Djonov V, Zuercher G, Andres AC, Ziemiecki A (Sep 1998). "Cell-type specific and estrogen dependent expression of the receptor tyrosine kinase EphB4 and its ligand ephrin-B2 during mammary gland morphogenesis".
2439:
1261:(EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in
1427:
Bonaldo MF, Yu MT, Jelenc P, Brown S, Su L, Lawton L, Deaven L, Efstratiadis A, Warburton D, Soares MB (Sep 1994). "Selection of cDNAs using chromosome-specific genomic clones: application to human chromosome 13".
2398:
2013:"The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3"
2713:
2432:
2425:
2079:
Holland SJ, Gale NW, Mbamalu G, Yancopoulos GD, Henkemeyer M, Pawson T (Oct 1996). "Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands".
341:
240:
4628:
1293:
at different levels of malignancy. For this reason, EFNB2 is likely to be associated with tumorigenesis and may be a potential prognostic marker for uterine cervical
2706:
5588:
2044:
Gale NW, Holland SJ, Valenzuela DM, Flenniken A, Pan L, Ryan TE, Henkemeyer M, Strebhardt K, Hirai H, Wilkinson DG, Pawson T, Davis S, Yancopoulos GD (Jul 1996).
5244:
4392:
2485:
4009:
2699:
944:
925:
163:
4067:
4929:
4619:
5714:
4224:
2681:
5690:
3209:
2892:
5709:
5607:
5557:
5528:
5475:
3962:
3829:
2368:
2348:
1409:
1655:
Bonaparte MI, Dimitrov AS, Bossart KN, Crameri G, Mungall BA, Bishop KA, Choudhry V, Dimitrov DS, Wang LF, Eaton BT, Broder CC (July 2005).
1391:
5286:
5282:
5278:
5274:
2827:
2811:
2594:
3555:
3474:
3341:
3258:
2643:
2579:
2383:
1176:
327:
5270:
2490:
1573:
Lackmann M, Mann RJ, Kravets L, Smith FM, Bucci TA, Maxwell KF, Howlett GJ, Olsson JE, Vanden Bos T, Cerretti DP, Boyd AW (Jun 1997).
1294:
1290:
2193:"Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4"
2011:
Cerretti DP, Lyman SD, Kozlosky CJ, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW (Apr 1996).
4959:
4078:
3638:
3249:
1827:
304:
1183:
2907:
2851:
2842:
2046:"Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis"
1978:
Cerretti DP, Vanden Bos T, Nelson N, Kozlosky CJ, Reddy P, Maraskovsky E, Park LS, Lyman SD, Copeland NG, Gilbert DJ (Nov 1995).
1534:
Cerretti DP, Vanden Bos T, Nelson N, Kozlosky CJ, Reddy P, Maraskovsky E, Park LS, Lyman SD, Copeland NG, Gilbert DJ (Nov 1995).
1463:
5481:
2589:
1378:
1357:
5568:
5544:
4684:
4240:
4103:
2658:
2480:
226:
201:
1374:
54:
5534:
1353:
5578:
3974:
3856:
3846:
2407:: Structural and biophysical characterization of the EPHB4-EPHRINB2 protein protein interaction and receptor specificity
143:
1614:
Williams SE, Mann F, Erskine L, Sakurai T, Wei S, Rossi DJ, Gale NW, Holt CE, Mason CA, Henkemeyer M (September 2003).
4924:
2663:
1306:
4949:
340:
239:
5683:
5563:
3389:
4944:
2256:
Torres R, Firestein BL, Dong H, Staudinger J, Olson EN, Huganir RL, Bredt DS, Gale NW, Yancopoulos GD (Dec 1998).
333:
232:
5471:
2341:
3655:
3571:
3490:
3357:
3274:
2584:
2564:
2470:
989:
151:
3089:
5255:
3002:
2877:
2465:
970:
4934:
5539:
5155:
5059:
4919:
4679:
4098:
3084:
2722:
2569:
2417:
2136:"Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee"
5676:
5613:
3810:
3454:
3094:
2733:
2449:
215:
5553:
4939:
3871:
3820:
2334:
2258:"PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands"
2088:
1938:
1668:
1282:
4689:
2764:
130:
4694:
4108:
3805:
2997:
2475:
1575:"Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor"
1159:
1134:
1130:
1126:
1096:
1071:
1067:
1063:
3730:
5312:
5225:
5170:
5124:
5069:
4804:
4744:
4372:
3745:
3675:
3234:
2832:
2774:
2725:
2574:
2122:
1913:
1516:
175:
5307:
5185:
5084:
4870:
4759:
4559:
4519:
4267:
4186:
4048:
3989:
3951:
3896:
3891:
3881:
3755:
3750:
3720:
3695:
3690:
3680:
3566:
3485:
3424:
3352:
3331:
3316:
3269:
2922:
1155:
1122:
1092:
1059:
5407:
5265:
5200:
5180:
5099:
5079:
4794:
4774:
4754:
4397:
3725:
3449:
2982:
2779:
5230:
5220:
5175:
5129:
5119:
5074:
4999:
4898:
4865:
4845:
4809:
4799:
4749:
4709:
4181:
4161:
4128:
3911:
3760:
2314:
2279:
2244:
2214:
2179:
2157:
2114:
2067:
2032:
1999:
1966:
1905:
1888:
Wilkinson DG (Mar 2001). "Multiple roles of EPH receptors and ephrins in neural development".
1876:
1833:
1823:
1794:
1765:
1736:
1696:
1637:
1596:
1555:
1508:
1445:
578:
123:
47:
5660:
5190:
5089:
4984:
4888:
4840:
4833:
4819:
4764:
4734:
4214:
4204:
4156:
4138:
3901:
3740:
3685:
5417:
4549:
2628:
2304:
2269:
2236:
2204:
2147:
2104:
2096:
2057:
2024:
1991:
1956:
1946:
1897:
1866:
1858:
1815:
1786:
1757:
1728:
1719:
Flanagan JG, Vanderhaeghen P (1998). "The ephrins and Eph receptors in neural development".
1686:
1676:
1627:
1586:
1547:
1498:
1490:
1437:
420:
351:
295:
250:
3941:
585:
171:
5029:
395:
2092:
1942:
1927:"Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk"
1851:
Philosophical
Transactions of the Royal Society of London. Series B, Biological Sciences
1672:
5603:
5524:
5466:
5160:
5009:
5004:
4118:
4113:
2759:
2749:
2744:
1871:
1846:
1806:
Wilkinson DG (2000). "Eph receptors and ephrins: regulators of guidance and assembly".
1777:
Holder N, Klein R (May 1999). "Eph receptors and ephrins: effectors of morphogenesis".
1691:
1656:
1262:
30:
2274:
2257:
2209:
2192:
2152:
2135:
2062:
2045:
1925:
Bennett BD, Zeigler FC, Gu Q, Fendly B, Goddard AD, Gillett N, Matthews W (Mar 1995).
1819:
1761:
859:
854:
849:
844:
839:
834:
829:
824:
819:
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809:
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724:
719:
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698:
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642:
637:
632:
627:
5703:
5656:
5297:
5210:
5139:
5109:
5044:
4954:
4908:
4784:
4714:
4659:
4648:
4133:
3841:
3524:
3429:
3321:
2457:
1995:
1961:
1926:
1917:
1551:
614:
2691:
1520:
5623:
5593:
5332:
5322:
5215:
5114:
4969:
4789:
4724:
4639:
4143:
3946:
3785:
3780:
3700:
3650:
3464:
3218:
3199:
3178:
3149:
2872:
2867:
2126:
1732:
1318:
413:
192:
155:
2293:"The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif"
1632:
1615:
179:
5583:
5549:
5447:
5437:
5432:
5422:
5372:
5195:
5094:
4855:
4769:
4699:
4594:
4357:
4322:
4272:
4235:
4171:
4053:
3984:
3936:
3926:
3921:
3916:
3800:
3795:
3790:
3168:
3079:
3069:
3037:
3032:
3027:
3022:
3012:
2972:
2937:
2668:
2653:
1414:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1396:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1329:
1325:
1931:
Proceedings of the
National Academy of Sciences of the United States of America
1661:
Proceedings of the
National Academy of Sciences of the United States of America
496:
5402:
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5362:
5352:
5342:
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5024:
5014:
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4814:
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4500:
4469:
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4407:
4352:
4327:
4307:
4292:
4282:
4176:
4093:
3886:
3866:
3765:
3710:
3705:
3529:
3434:
3419:
3214:
3173:
3145:
3114:
3074:
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2927:
2902:
2897:
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2800:
2794:
2784:
2648:
2633:
2606:
312:
209:
159:
1591:
1574:
5427:
5397:
5392:
5387:
5382:
5377:
5357:
5347:
5337:
5327:
5019:
4979:
4875:
4850:
4609:
4604:
4599:
4589:
4584:
4579:
4569:
4490:
4428:
4362:
4342:
4337:
4332:
4317:
4312:
4302:
4297:
4191:
4166:
3931:
3851:
3770:
3715:
3605:
3544:
3534:
3439:
3326:
3124:
3119:
3109:
3017:
3007:
2992:
2967:
2962:
2952:
2947:
2942:
2559:
2240:
1980:"Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases"
1790:
1681:
1657:"Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus"
1536:"Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases"
889:
556:
434:
379:
366:
278:
265:
167:
2309:
2292:
2028:
1951:
1909:
1880:
1862:
1837:
1798:
1700:
1641:
1512:
1441:
2318:
2283:
2248:
2218:
2183:
2161:
2118:
2071:
2036:
2003:
1970:
1769:
1740:
1600:
1559:
1449:
1223:
1218:
5598:
5317:
4974:
4574:
4564:
4544:
4479:
4448:
4417:
4381:
4287:
4277:
3624:
3104:
3047:
2957:
2917:
2601:
1616:"Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm"
1503:
1286:
1207:
1034:
1015:
5573:
4994:
4459:
3861:
2822:
1239:
1001:
956:
1494:
100:
96:
92:
88:
84:
80:
76:
5486:
5150:
5039:
4964:
4669:
4664:
4088:
4083:
4037:
4033:
4029:
4025:
4021:
4017:
4013:
3665:
3204:
2882:
2500:
2109:
2100:
1901:
1258:
1191:
911:
5644:
2012:
1979:
1535:
855:
regulation of postsynaptic neurotransmitter receptor internalization
850:
regulation of postsynaptic membrane neurotransmitter receptor levels
5518:
5514:
5510:
5506:
5502:
5498:
5494:
5490:
5205:
5104:
4779:
4719:
4533:
4256:
4252:
4248:
4244:
3735:
3599:
3518:
3514:
3413:
3409:
3405:
3401:
3310:
3306:
3157:
2638:
2543:
2538:
2533:
2528:
2523:
2518:
2513:
2508:
1314:
1310:
1270:
1266:
874:
870:
5652:
4989:
3595:
3591:
3587:
3583:
3579:
3575:
3510:
3506:
3502:
3498:
3494:
3397:
3393:
3385:
3381:
3377:
3373:
3369:
3365:
3361:
3302:
3298:
3294:
3290:
3286:
3282:
3278:
3230:
3226:
3222:
3188:
3153:
3134:
2621:
2616:
2611:
1246:
147:
2695:
2421:
2330:
594:
2326:
1847:"Roles of Eph receptors and ephrins in segmental patterning"
1281:
EFNB2 gene has been observed progressively downregulated in
1748:
Zhou R (Mar 1998). "The Eph family receptors and ligands".
800:
positive regulation of cardiac muscle cell differentiation
403:
5664:
5589:
Pituitary adenylate cyclase-activating peptide (PACAP)
2377:: CRYSTAL STRUCTURE OF THE MURINE EPHRIN-B2 ECTODOMAIN
1324:
EFNB2 has also been shown to serve as a receptor for
568:
835:
negative regulation of neuron projection development
820:
positive regulation of cell population proliferation
5456:
5243:
5138:
4907:
4647:
4638:
4618:
4532:
4509:
4478:
4447:
4416:
4380:
4371:
4223:
4066:
3999:
3961:
3828:
3819:
3637:
3614:
3554:
3473:
3340:
3257:
3248:
3187:
3133:
3046:
2850:
2841:
2810:
2732:
2552:
2499:
2456:
1148:
1115:
1085:
1052:
704:
integral component of postsynaptic density membrane
5535:Glucose-6-phosphate isomerase (GPI; PGI, PHI, AMF)
4393:Glial cell line-derived neurotrophic factor (GDNF)
4046:Cleavage products/derivatives with unknown target:
1370:
1368:
1366:
1349:
1347:
1345:
2392:: Crystal Structure of the EphB2-ephrinB2 complex
2291:Lin D, Gish GD, Songyang Z, Pawson T (Feb 1999).
765:cell migration involved in sprouting angiogenesis
730:negative regulation of keratinocyte proliferation
350:
249:
5569:Macrophage-stimulating protein (MSP; HLP, HGFLP)
2448:Intercellular signaling peptides and proteins /
3210:Heparin-binding EGF-like growth factor (HB-EGF)
2893:Heparin-binding EGF-like growth factor (HB-EGF)
18:Protein-coding gene in the species Homo sapiens
1475:
1473:
1375:GRCm38: Ensembl release 89: ENSMUSG00000001300
5684:
5621:Additional growth factor receptor modulators:
2707:
2433:
2342:
8:
3975:Insulin-like growth factor-2 (somatomedin A)
3857:Insulin-like growth factor-2 (somatomedin A)
3847:Insulin-like growth factor-1 (somatomedin C)
1845:Xu Q, Mellitzer G, Wilkinson DG (Jul 2000).
2486:Transforming growth factor beta superfamily
1354:GRCh38: Ensembl release 89: ENSG00000125266
5691:
5677:
4644:
4377:
3825:
3254:
2847:
2714:
2700:
2692:
2440:
2426:
2418:
2349:
2335:
2327:
2191:Wang HU, Chen ZF, Anderson DJ (May 1998).
885:
815:positive regulation of aorta morphogenesis
699:integral component of presynaptic membrane
610:
391:
290:
187:
65:
2308:
2273:
2208:
2151:
2108:
2061:
1960:
1950:
1870:
1690:
1680:
1631:
1590:
1502:
5579:Migration-stimulating factor (MSF; PRG4)
2908:Transforming growth factor alpha (TGFα)
2364:
1341:
5482:Connective tissue growth factor (CTGF)
134:, EPLG5, HTKL, Htk-L, LERK5, ephrin B2
20:
5545:Hepatoma-derived growth factor (HDGF)
2134:Ephnomenclaturecommittee (Aug 1997).
684:integral component of plasma membrane
355:
316:
311:
254:
213:
208:
7:
5641:
5639:
2595:Nephroblastoma overexpressed protein
543:vestibular membrane of cochlear duct
2644:Parathyroid hormone-related protein
2580:CCN intercellular signaling protein
2297:The Journal of Biological Chemistry
1579:The Journal of Biological Chemistry
860:positive regulation of neuron death
5663:. You can help Knowledge (XXG) by
2491:Vascular endothelial growth factor
1257:This gene encodes a member of the
1145:
1112:
1082:
1049:
1025:
1006:
980:
961:
935:
916:
770:multicellular organism development
745:anatomical structure morphogenesis
573:
491:
429:
408:
14:
1242:that in humans is encoded by the
840:peptidyl-tyrosine phosphorylation
825:ephrin receptor signaling pathway
810:venous blood vessel morphogenesis
689:Schaffer collateral - CA1 synapse
5643:
5564:Leukemia inhibitory factor (LIF)
2397:
2382:
2367:
1808:International Review of Cytology
1332:into the cell during infection.
648:protein tyrosine kinase activity
584:
577:
339:
332:
326:
303:
238:
231:
225:
200:
29:
4732:Negative allosteric modulators:
2590:Connective tissue growth factor
1750:Pharmacology & Therapeutics
5715:Human chromosome 13 gene stubs
5050:Gossypetin (3,5,7,8,3',4'-HHF)
4241:Platelet-derived growth factor
2682:extracellular ligand disorders
2659:Tolloid-like metalloproteinase
2481:Platelet-derived growth factor
1733:10.1146/annurev.neuro.21.1.309
1464:"Entrez Gene: EFNB2 ephrin-B2"
1289:derived from uterine cervical
664:integral component of membrane
595:More reference expression data
557:More reference expression data
1:
5256:Placental growth factor (PGF)
2275:10.1016/S0896-6273(00)80663-7
2210:10.1016/S0092-8674(00)81436-1
2153:10.1016/S0092-8674(00)80500-0
2063:10.1016/S0896-6273(00)80276-7
1820:10.1016/S0074-7696(00)96005-4
1762:10.1016/S0163-7258(97)00112-5
1721:Annual Review of Neuroscience
324:
223:
5710:Genes on human chromosome 13
5540:Glia maturation factor (GMF)
4049:Glypromate (GPE, (1-3)IGF-1)
1996:10.1016/0161-5890(95)00108-5
1890:Nature Reviews. Neuroscience
1633:10.1016/j.neuron.2003.08.017
1552:10.1016/0161-5890(95)00108-5
1326:Hendra Virus and Nipah Virus
5731:
5638:
5472:Colony-stimulating factors
5464:Additional growth factors:
1177:Chr 13: 106.49 – 106.54 Mb
795:viral entry into host cell
790:animal organ morphogenesis
780:nephric duct morphogenesis
760:nervous system development
725:blood vessel morphogenesis
638:signaling receptor binding
4820:SNA-120 (pegylated K252a)
3992:(against IGF-1 and IGF-2)
3954:(against IGF-1 and IGF-2)
2677:
2362:
1410:"Mouse PubMed Reference:"
1392:"Human PubMed Reference:"
1222:
1217:
1213:
1206:
1190:
1171:
1152:
1119:
1108:
1089:
1056:
1045:
1032:
1028:
1013:
1009:
1000:
987:
983:
968:
964:
955:
942:
938:
923:
919:
910:
895:
888:
884:
868:
613:
609:
592:
576:
567:
554:
511:medullary collecting duct
503:
494:
441:
432:
402:
394:
390:
373:
360:
323:
302:
293:
289:
272:
259:
222:
199:
190:
186:
141:
138:
128:
121:
116:
73:
68:
51:
46:
41:
37:
28:
23:
3656:Hepatocyte growth factor
3215:Neuregulins (heregulins)
3146:Neuregulins (heregulins)
3090:Trastuzumab duocarmazine
2803:(against angiopoietin 2)
2797:(against angiopoietin 3)
2585:Cysteine-rich protein 61
2565:Agouti signaling protein
2471:Fibroblast growth factor
2172:Clinical Cancer Research
1592:10.1074/jbc.272.26.16521
1430:Human Molecular Genetics
1305:EFNB2 has been shown to
1287:neoplastic keratinocytes
755:lymph vessel development
735:regulation of chemotaxis
523:Rostral migratory stream
3003:Depatuxizumab mafodotin
2466:Epidermal growth factor
2241:10.1242/jcs.111.18.2741
2229:Journal of Cell Science
1791:10.1242/dev.126.10.2033
1682:10.1073/pnas.0504887102
643:ephrin receptor binding
628:virus receptor activity
453:mucosa of sigmoid colon
5626:(neurotrophin mixture)
5614:Wnt signaling proteins
5295:Allosteric modulators:
5015:Norwogonin (5,7,8-THF)
3235:5 (tomoregulin, TMEFF)
3085:Trastuzumab deruxtecan
2723:Growth factor receptor
2570:Agouti-related protein
2310:10.1074/jbc.274.6.3726
2029:10.1006/geno.1996.0192
1952:10.1073/pnas.92.6.1866
1863:10.1098/rstb.2000.0635
507:lumbar spinal ganglion
5554:T-cell growth factors
3811:Telisotuzumab vedotin
3095:Trastuzumab emtansine
2664:Tumor necrosis factor
1295:preneoplastic lesions
1291:preneoplastic lesions
1184:Chr 8: 8.67 – 8.71 Mb
694:glutamatergic synapse
357:8 A1.1|8 3.42 cM
216:Chromosome 13 (human)
4139:EVT-901 (SAR-127963)
3872:Mecasermin rinfabate
1984:Molecular Immunology
1540:Molecular Immunology
1442:10.1093/hmg/3.9.1663
1283:Human papillomavirus
750:T cell costimulation
720:cell differentiation
318:Chromosome 8 (mouse)
69:List of PDB id codes
42:Available structures
2476:Nerve growth factor
2093:1996Natur.383..722H
1943:1995PNAS...92.1866B
1673:2005PNAS..10210652B
845:presynapse assembly
740:cell-cell signaling
535:ganglionic eminence
449:ganglionic eminence
5651:This article on a
5305:Kinase inhibitors:
5168:Kinase inhibitors:
5067:Kinase inhibitors:
4742:Kinase inhibitors:
4557:Kinase inhibitors:
4517:Kinase inhibitors:
4498:Kinase inhibitors:
4467:Kinase inhibitors:
4436:Kinase inhibitors:
4405:Kinase inhibitors:
4265:Kinase inhibitors:
3879:Kinase inhibitors:
3673:Kinase inhibitors:
3462:Kinase inhibitors:
3455:Aprutumab ixadotin
3102:Kinase inhibitors:
2915:Kinase inhibitors:
2772:Kinase inhibitors:
2575:Angiogenic protein
1857:(1399): 993–1002.
990:ENSMUSG00000001300
713:Biological process
657:Cellular component
621:Molecular function
5672:
5671:
5633:
5632:
5239:
5238:
5000:N-Acetylserotonin
4899:ReN-1820 (TrkAd5)
4528:
4527:
4062:
4061:
4007:Binding proteins:
3666:Dihexa (PNB-0408)
3633:
3632:
3244:
3243:
3158:6 (neuroglycan C)
2878:EGF (urogastrone)
2856:
2689:
2688:
2415:
2414:
1495:10.1002/jcp.24808
1233:
1232:
1229:
1228:
1202:
1201:
1167:
1166:
1142:
1141:
1104:
1103:
1079:
1078:
1041:
1040:
1022:
1021:
996:
995:
977:
976:
951:
950:
932:
931:
880:
879:
605:
604:
601:
600:
563:
562:
550:
549:
488:
487:
469:periodontal fiber
386:
385:
285:
284:
180:EFNB2 - orthologs
112:
111:
108:
107:
52:Ortholog search:
5722:
5693:
5686:
5679:
5647:
5640:
5445:Decoy receptors:
5418:Alacizumab pegol
4896:Decoy receptors:
4645:
4550:Stem cell factor
4491:Persephin (PSPN)
4429:Neurturin (NRTN)
4378:
4215:LEVI-04 (p75-Fc)
4212:Decoy receptors:
3826:
3255:
2854:
2848:
2716:
2709:
2702:
2693:
2629:Hedgehog protein
2442:
2435:
2428:
2419:
2401:
2386:
2371:
2351:
2344:
2337:
2328:
2322:
2312:
2287:
2277:
2252:
2222:
2212:
2187:
2165:
2155:
2130:
2112:
2101:10.1038/383722a0
2075:
2065:
2040:
2007:
1990:(16): 1197–205.
1974:
1964:
1954:
1921:
1902:10.1038/35058515
1884:
1874:
1841:
1802:
1773:
1744:
1705:
1704:
1694:
1684:
1652:
1646:
1645:
1635:
1611:
1605:
1604:
1594:
1585:(26): 16521–30.
1570:
1564:
1563:
1546:(16): 1197–205.
1531:
1525:
1524:
1506:
1477:
1468:
1467:
1460:
1454:
1453:
1424:
1418:
1417:
1406:
1400:
1399:
1388:
1382:
1372:
1361:
1351:
1215:
1214:
1186:
1179:
1162:
1146:
1137:
1113:
1109:RefSeq (protein)
1099:
1083:
1074:
1050:
1026:
1007:
981:
962:
936:
917:
886:
611:
597:
588:
581:
574:
559:
499:
497:Top expressed in
492:
473:secondary oocyte
445:ventricular zone
437:
435:Top expressed in
430:
409:
392:
382:
369:
358:
343:
336:
330:
319:
307:
291:
281:
268:
257:
242:
235:
229:
218:
204:
188:
182:
133:
126:
103:
66:
60:
39:
38:
33:
21:
5730:
5729:
5725:
5724:
5723:
5721:
5720:
5719:
5700:
5699:
5698:
5697:
5636:
5634:
5629:
5574:Midkine (NEGF2)
5452:
5235:
5134:
4903:
4841:ABT-110 (PG110)
4634:
4614:
4524:
4505:
4474:
4443:
4412:
4367:
4219:
4157:ABT-110 (PG110)
4058:
3995:
3957:
3815:
3629:
3610:
3550:
3547:(against FGF23)
3469:
3336:
3240:
3183:
3129:
3042:
2853:
2837:
2806:
2728:
2720:
2690:
2685:
2673:
2548:
2495:
2452:
2446:
2416:
2411:
2408:
2402:
2393:
2387:
2378:
2372:
2358:
2355:
2325:
2290:
2255:
2235:(18): 2741–51.
2225:
2190:
2168:
2133:
2087:(6602): 722–5.
2078:
2043:
2010:
1977:
1924:
1887:
1844:
1830:
1805:
1785:(10): 2033–44.
1776:
1747:
1718:
1714:
1712:Further reading
1709:
1708:
1667:(30): 10652–7.
1654:
1653:
1649:
1613:
1612:
1608:
1572:
1571:
1567:
1533:
1532:
1528:
1479:
1478:
1471:
1462:
1461:
1457:
1426:
1425:
1421:
1408:
1407:
1403:
1390:
1389:
1385:
1373:
1364:
1352:
1343:
1338:
1303:
1279:
1255:
1224:View/Edit Mouse
1219:View/Edit Human
1182:
1175:
1172:Location (UCSC)
1158:
1154:
1133:
1129:
1125:
1121:
1095:
1091:
1070:
1066:
1062:
1058:
971:ENSG00000125266
864:
708:
679:plasma membrane
652:
633:protein binding
593:
583:
582:
555:
546:
541:
537:
533:
529:
525:
521:
517:
515:renal corpuscle
513:
509:
495:
484:
479:
475:
471:
467:
465:parietal pleura
463:
459:
457:visceral pleura
455:
451:
447:
433:
377:
364:
356:
346:
345:
344:
337:
317:
294:Gene location (
276:
263:
255:
245:
244:
243:
236:
214:
191:Gene location (
142:
129:
122:
75:
53:
19:
12:
11:
5:
5728:
5726:
5718:
5717:
5712:
5702:
5701:
5696:
5695:
5688:
5681:
5673:
5670:
5669:
5648:
5631:
5630:
5628:
5627:
5617:
5616:
5611:
5604:Thrombopoietin
5601:
5596:
5591:
5586:
5581:
5576:
5571:
5566:
5561:
5547:
5542:
5537:
5532:
5525:Erythropoietin
5522:
5484:
5479:
5469:
5467:Adrenomedullin
5460:
5458:
5454:
5453:
5451:
5450:
5441:
5440:
5435:
5430:
5425:
5420:
5411:
5410:
5405:
5400:
5395:
5390:
5385:
5380:
5375:
5370:
5365:
5360:
5355:
5350:
5345:
5340:
5335:
5330:
5325:
5320:
5315:
5310:
5301:
5300:
5291:
5290:
5268:
5263:
5258:
5249:
5247:
5241:
5240:
5237:
5236:
5234:
5233:
5228:
5223:
5218:
5213:
5208:
5203:
5198:
5193:
5188:
5183:
5178:
5173:
5164:
5163:
5158:
5153:
5144:
5142:
5136:
5135:
5133:
5132:
5127:
5122:
5117:
5112:
5107:
5102:
5097:
5092:
5087:
5082:
5077:
5072:
5063:
5062:
5053:
5052:
5047:
5042:
5033:
5032:
5027:
5022:
5017:
5012:
5007:
5002:
4997:
4992:
4987:
4982:
4977:
4972:
4967:
4962:
4957:
4952:
4947:
4942:
4937:
4932:
4930:4'-DMA-7,8-DHF
4927:
4922:
4913:
4911:
4905:
4904:
4902:
4901:
4892:
4891:
4879:
4878:
4873:
4868:
4863:
4858:
4853:
4848:
4843:
4824:
4823:
4817:
4812:
4807:
4802:
4797:
4792:
4787:
4782:
4777:
4772:
4767:
4762:
4757:
4752:
4747:
4738:
4737:
4728:
4727:
4722:
4717:
4712:
4703:
4702:
4697:
4692:
4690:Gambogic amide
4687:
4682:
4677:
4672:
4667:
4662:
4653:
4651:
4642:
4636:
4635:
4633:
4632:
4624:
4622:
4616:
4615:
4613:
4612:
4607:
4602:
4597:
4592:
4587:
4582:
4577:
4572:
4567:
4562:
4553:
4552:
4547:
4538:
4536:
4530:
4529:
4526:
4525:
4523:
4522:
4513:
4511:
4507:
4506:
4504:
4503:
4494:
4493:
4484:
4482:
4476:
4475:
4473:
4472:
4463:
4462:
4460:Artemin (ARTN)
4453:
4451:
4445:
4444:
4442:
4441:
4432:
4431:
4422:
4420:
4414:
4413:
4411:
4410:
4401:
4400:
4395:
4386:
4384:
4375:
4369:
4368:
4366:
4365:
4360:
4355:
4346:
4345:
4340:
4335:
4330:
4325:
4320:
4315:
4310:
4305:
4300:
4295:
4290:
4285:
4280:
4275:
4270:
4261:
4260:
4238:
4229:
4227:
4221:
4220:
4218:
4217:
4208:
4207:
4195:
4194:
4189:
4184:
4179:
4174:
4169:
4164:
4159:
4147:
4146:
4141:
4136:
4131:
4122:
4121:
4116:
4111:
4106:
4101:
4096:
4091:
4086:
4081:
4072:
4070:
4064:
4063:
4060:
4059:
4057:
4056:
4051:
4042:
4041:
4003:
4001:
3997:
3996:
3994:
3993:
3987:
3978:
3977:
3967:
3965:
3959:
3958:
3956:
3955:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3905:
3904:
3899:
3894:
3889:
3884:
3875:
3874:
3869:
3864:
3859:
3854:
3849:
3844:
3834:
3832:
3823:
3817:
3816:
3814:
3813:
3808:
3803:
3798:
3793:
3788:
3783:
3774:
3773:
3768:
3763:
3758:
3753:
3748:
3743:
3738:
3733:
3728:
3723:
3718:
3713:
3708:
3703:
3698:
3693:
3688:
3683:
3678:
3669:
3668:
3659:
3658:
3653:
3643:
3641:
3635:
3634:
3631:
3630:
3628:
3627:
3618:
3616:
3612:
3611:
3609:
3608:
3603:
3569:
3560:
3558:
3552:
3551:
3549:
3548:
3538:
3537:
3532:
3527:
3522:
3488:
3479:
3477:
3471:
3470:
3468:
3467:
3458:
3457:
3452:
3443:
3442:
3437:
3432:
3427:
3422:
3417:
3355:
3346:
3344:
3338:
3337:
3335:
3334:
3329:
3324:
3319:
3314:
3272:
3263:
3261:
3252:
3246:
3245:
3242:
3241:
3239:
3238:
3212:
3207:
3202:
3193:
3191:
3185:
3184:
3182:
3181:
3176:
3171:
3162:
3161:
3139:
3137:
3131:
3130:
3128:
3127:
3122:
3117:
3112:
3107:
3098:
3097:
3092:
3087:
3082:
3077:
3072:
3063:
3062:
3052:
3050:
3044:
3043:
3041:
3040:
3035:
3030:
3025:
3020:
3015:
3010:
3005:
3000:
2995:
2986:
2985:
2980:
2975:
2970:
2965:
2960:
2955:
2950:
2945:
2940:
2935:
2930:
2925:
2920:
2911:
2910:
2905:
2900:
2895:
2890:
2885:
2880:
2875:
2870:
2860:
2858:
2845:
2839:
2838:
2836:
2835:
2830:
2825:
2816:
2814:
2808:
2807:
2805:
2804:
2798:
2788:
2787:
2782:
2777:
2768:
2767:
2765:Angiopoietin 3
2762:
2760:Angiopoietin 2
2753:
2752:
2750:Angiopoietin 4
2747:
2745:Angiopoietin 1
2738:
2736:
2730:
2729:
2721:
2719:
2718:
2711:
2704:
2696:
2687:
2686:
2678:
2675:
2674:
2672:
2671:
2666:
2661:
2656:
2651:
2646:
2641:
2636:
2631:
2626:
2625:
2624:
2619:
2614:
2604:
2599:
2598:
2597:
2592:
2587:
2577:
2572:
2567:
2562:
2556:
2554:
2550:
2549:
2547:
2546:
2541:
2536:
2531:
2526:
2521:
2516:
2511:
2505:
2503:
2497:
2496:
2494:
2493:
2488:
2483:
2478:
2473:
2468:
2462:
2460:
2458:Growth factors
2454:
2453:
2447:
2445:
2444:
2437:
2430:
2422:
2413:
2412:
2410:
2409:
2403:
2396:
2394:
2388:
2381:
2379:
2373:
2366:
2363:
2360:
2359:
2356:
2354:
2353:
2346:
2339:
2331:
2324:
2323:
2303:(6): 3726–33.
2288:
2268:(6): 1453–63.
2253:
2223:
2188:
2166:
2131:
2076:
2041:
2008:
1975:
1937:(6): 1866–70.
1922:
1885:
1842:
1828:
1803:
1774:
1745:
1715:
1713:
1710:
1707:
1706:
1647:
1606:
1565:
1526:
1489:(4): 802–812.
1483:J Cell Physiol
1469:
1455:
1436:(9): 1663–73.
1419:
1401:
1383:
1362:
1340:
1339:
1337:
1334:
1302:
1299:
1278:
1275:
1263:erythropoiesis
1254:
1251:
1231:
1230:
1227:
1226:
1221:
1211:
1210:
1204:
1203:
1200:
1199:
1197:
1195:
1188:
1187:
1180:
1173:
1169:
1168:
1165:
1164:
1150:
1149:
1143:
1140:
1139:
1117:
1116:
1110:
1106:
1105:
1102:
1101:
1087:
1086:
1080:
1077:
1076:
1054:
1053:
1047:
1043:
1042:
1039:
1038:
1030:
1029:
1023:
1020:
1019:
1011:
1010:
1004:
998:
997:
994:
993:
985:
984:
978:
975:
974:
966:
965:
959:
953:
952:
949:
948:
940:
939:
933:
930:
929:
921:
920:
914:
908:
907:
902:
897:
893:
892:
882:
881:
878:
877:
866:
865:
863:
862:
857:
852:
847:
842:
837:
832:
827:
822:
817:
812:
807:
802:
797:
792:
787:
782:
777:
772:
767:
762:
757:
752:
747:
742:
737:
732:
727:
722:
716:
714:
710:
709:
707:
706:
701:
696:
691:
686:
681:
676:
674:focal adhesion
671:
666:
660:
658:
654:
653:
651:
650:
645:
640:
635:
630:
624:
622:
618:
617:
607:
606:
603:
602:
599:
598:
590:
589:
571:
565:
564:
561:
560:
552:
551:
548:
547:
545:
544:
540:
536:
532:
528:
524:
520:
516:
512:
508:
504:
501:
500:
489:
486:
485:
483:
482:
478:
474:
470:
466:
462:
461:amniotic fluid
458:
454:
450:
446:
442:
439:
438:
426:
425:
417:
406:
400:
399:
396:RNA expression
388:
387:
384:
383:
375:
371:
370:
362:
359:
354:
348:
347:
338:
331:
325:
321:
320:
315:
309:
308:
300:
299:
287:
286:
283:
282:
274:
270:
269:
261:
258:
253:
247:
246:
237:
230:
224:
220:
219:
212:
206:
205:
197:
196:
184:
183:
140:
136:
135:
127:
119:
118:
114:
113:
110:
109:
106:
105:
71:
70:
62:
61:
50:
44:
43:
35:
34:
26:
25:
17:
13:
10:
9:
6:
4:
3:
2:
5727:
5716:
5713:
5711:
5708:
5707:
5705:
5694:
5689:
5687:
5682:
5680:
5675:
5674:
5668:
5666:
5662:
5658:
5657:chromosome 13
5654:
5649:
5646:
5642:
5637:
5625:
5622:
5619:
5618:
5615:
5612:
5609:
5605:
5602:
5600:
5597:
5595:
5592:
5590:
5587:
5585:
5582:
5580:
5577:
5575:
5572:
5570:
5567:
5565:
5562:
5559:
5555:
5551:
5548:
5546:
5543:
5541:
5538:
5536:
5533:
5530:
5526:
5523:
5520:
5516:
5512:
5508:
5504:
5500:
5496:
5492:
5488:
5485:
5483:
5480:
5477:
5473:
5470:
5468:
5465:
5462:
5461:
5459:
5455:
5449:
5446:
5443:
5442:
5439:
5436:
5434:
5431:
5429:
5426:
5424:
5421:
5419:
5416:
5413:
5412:
5409:
5406:
5404:
5401:
5399:
5396:
5394:
5391:
5389:
5386:
5384:
5381:
5379:
5376:
5374:
5371:
5369:
5366:
5364:
5361:
5359:
5356:
5354:
5351:
5349:
5346:
5344:
5341:
5339:
5336:
5334:
5331:
5329:
5326:
5324:
5321:
5319:
5316:
5314:
5311:
5309:
5306:
5303:
5302:
5299:
5298:Cyclotraxin B
5296:
5293:
5292:
5288:
5284:
5280:
5276:
5272:
5269:
5267:
5264:
5262:
5259:
5257:
5254:
5251:
5250:
5248:
5246:
5242:
5232:
5229:
5227:
5224:
5222:
5219:
5217:
5214:
5212:
5211:Larotrectinib
5209:
5207:
5204:
5202:
5199:
5197:
5194:
5192:
5189:
5187:
5184:
5182:
5179:
5177:
5174:
5172:
5169:
5166:
5165:
5162:
5159:
5157:
5154:
5152:
5149:
5146:
5145:
5143:
5141:
5137:
5131:
5128:
5126:
5123:
5121:
5118:
5116:
5113:
5111:
5110:Larotrectinib
5108:
5106:
5103:
5101:
5098:
5096:
5093:
5091:
5088:
5086:
5083:
5081:
5078:
5076:
5073:
5071:
5068:
5065:
5064:
5061:
5058:
5055:
5054:
5051:
5048:
5046:
5045:Cyclotraxin B
5043:
5041:
5038:
5035:
5034:
5031:
5028:
5026:
5023:
5021:
5018:
5016:
5013:
5011:
5008:
5006:
5003:
5001:
4998:
4996:
4993:
4991:
4988:
4986:
4983:
4981:
4978:
4976:
4973:
4971:
4968:
4966:
4963:
4961:
4958:
4956:
4955:Amitriptyline
4953:
4951:
4948:
4946:
4943:
4941:
4938:
4936:
4933:
4931:
4928:
4926:
4923:
4921:
4918:
4915:
4914:
4912:
4910:
4906:
4900:
4897:
4894:
4893:
4890:
4887:
4884:
4881:
4880:
4877:
4874:
4872:
4869:
4867:
4864:
4862:
4859:
4857:
4854:
4852:
4849:
4847:
4844:
4842:
4839:
4835:
4832:
4831:Against TrkA:
4829:
4826:
4825:
4821:
4818:
4816:
4813:
4811:
4808:
4806:
4803:
4801:
4798:
4796:
4793:
4791:
4788:
4786:
4785:Larotrectinib
4783:
4781:
4778:
4776:
4773:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4740:
4739:
4736:
4733:
4730:
4729:
4726:
4723:
4721:
4718:
4716:
4715:Dexamethasone
4713:
4711:
4708:
4705:
4704:
4701:
4698:
4696:
4693:
4691:
4688:
4686:
4683:
4681:
4678:
4676:
4673:
4671:
4668:
4666:
4663:
4661:
4660:Amitriptyline
4658:
4655:
4654:
4652:
4650:
4646:
4643:
4641:
4637:
4630:
4626:
4625:
4623:
4621:
4617:
4611:
4608:
4606:
4603:
4601:
4598:
4596:
4593:
4591:
4588:
4586:
4583:
4581:
4578:
4576:
4573:
4571:
4568:
4566:
4563:
4561:
4558:
4555:
4554:
4551:
4548:
4546:
4543:
4540:
4539:
4537:
4535:
4531:
4521:
4518:
4515:
4514:
4512:
4508:
4502:
4499:
4496:
4495:
4492:
4489:
4486:
4485:
4483:
4481:
4477:
4471:
4468:
4465:
4464:
4461:
4458:
4455:
4454:
4452:
4450:
4446:
4440:
4437:
4434:
4433:
4430:
4427:
4424:
4423:
4421:
4419:
4415:
4409:
4406:
4403:
4402:
4399:
4396:
4394:
4391:
4388:
4387:
4385:
4383:
4379:
4376:
4374:
4370:
4364:
4361:
4359:
4356:
4354:
4351:
4348:
4347:
4344:
4341:
4339:
4336:
4334:
4331:
4329:
4326:
4324:
4321:
4319:
4316:
4314:
4311:
4309:
4306:
4304:
4301:
4299:
4296:
4294:
4291:
4289:
4286:
4284:
4281:
4279:
4276:
4274:
4271:
4269:
4266:
4263:
4262:
4258:
4254:
4250:
4246:
4242:
4239:
4237:
4234:
4231:
4230:
4228:
4226:
4222:
4216:
4213:
4210:
4209:
4206:
4203:
4200:
4197:
4196:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4160:
4158:
4155:
4152:
4149:
4148:
4145:
4142:
4140:
4137:
4135:
4134:Dexamethasone
4132:
4130:
4127:
4124:
4123:
4120:
4117:
4115:
4112:
4110:
4107:
4105:
4102:
4100:
4097:
4095:
4092:
4090:
4087:
4085:
4082:
4080:
4077:
4074:
4073:
4071:
4069:
4065:
4055:
4052:
4050:
4047:
4044:
4043:
4039:
4035:
4031:
4027:
4023:
4019:
4015:
4011:
4008:
4005:
4004:
4002:
3998:
3991:
3988:
3986:
3983:
3980:
3979:
3976:
3972:
3969:
3968:
3966:
3964:
3960:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3907:
3906:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3883:
3880:
3877:
3876:
3873:
3870:
3868:
3865:
3863:
3860:
3858:
3855:
3853:
3850:
3848:
3845:
3843:
3842:des(1-3)IGF-1
3839:
3836:
3835:
3833:
3831:
3827:
3824:
3822:
3818:
3812:
3809:
3807:
3806:Telisotuzumab
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3782:
3779:
3776:
3775:
3772:
3769:
3767:
3764:
3762:
3759:
3757:
3754:
3752:
3749:
3747:
3744:
3742:
3739:
3737:
3734:
3732:
3729:
3727:
3724:
3722:
3719:
3717:
3714:
3712:
3709:
3707:
3704:
3702:
3699:
3697:
3694:
3692:
3689:
3687:
3684:
3682:
3679:
3677:
3674:
3671:
3670:
3667:
3664:
3663:Potentiators:
3661:
3660:
3657:
3654:
3652:
3648:
3645:
3644:
3642:
3640:
3636:
3626:
3623:
3620:
3619:
3617:
3613:
3607:
3604:
3601:
3597:
3593:
3589:
3585:
3581:
3577:
3573:
3570:
3568:
3565:
3562:
3561:
3559:
3557:
3553:
3546:
3543:
3540:
3539:
3536:
3533:
3531:
3528:
3526:
3525:Selpercatinib
3523:
3520:
3516:
3512:
3508:
3504:
3500:
3496:
3492:
3489:
3487:
3484:
3481:
3480:
3478:
3476:
3472:
3466:
3463:
3460:
3459:
3456:
3453:
3451:
3448:
3445:
3444:
3441:
3438:
3436:
3433:
3431:
3430:Selpercatinib
3428:
3426:
3423:
3421:
3418:
3415:
3411:
3407:
3403:
3399:
3395:
3391:
3387:
3383:
3379:
3375:
3371:
3367:
3363:
3359:
3356:
3354:
3351:
3348:
3347:
3345:
3343:
3339:
3333:
3330:
3328:
3325:
3323:
3322:Selpercatinib
3320:
3318:
3315:
3312:
3308:
3304:
3300:
3296:
3292:
3288:
3284:
3280:
3276:
3273:
3271:
3268:
3265:
3264:
3262:
3260:
3256:
3253:
3251:
3247:
3236:
3232:
3228:
3224:
3220:
3216:
3213:
3211:
3208:
3206:
3203:
3201:
3198:
3195:
3194:
3192:
3190:
3186:
3180:
3177:
3175:
3172:
3170:
3167:
3164:
3163:
3159:
3155:
3151:
3147:
3144:
3141:
3140:
3138:
3136:
3132:
3126:
3123:
3121:
3118:
3116:
3113:
3111:
3108:
3106:
3103:
3100:
3099:
3096:
3093:
3091:
3088:
3086:
3083:
3081:
3078:
3076:
3073:
3071:
3068:
3065:
3064:
3061:
3057:
3054:
3053:
3051:
3049:
3045:
3039:
3036:
3034:
3031:
3029:
3026:
3024:
3021:
3019:
3016:
3014:
3011:
3009:
3006:
3004:
3001:
2999:
2998:Depatuxizumab
2996:
2994:
2991:
2988:
2987:
2984:
2981:
2979:
2976:
2974:
2971:
2969:
2966:
2964:
2961:
2959:
2956:
2954:
2951:
2949:
2946:
2944:
2941:
2939:
2936:
2934:
2931:
2929:
2926:
2924:
2921:
2919:
2916:
2913:
2912:
2909:
2906:
2904:
2901:
2899:
2896:
2894:
2891:
2889:
2886:
2884:
2881:
2879:
2876:
2874:
2871:
2869:
2865:
2862:
2861:
2859:
2857:
2849:
2846:
2844:
2840:
2834:
2831:
2829:
2826:
2824:
2821:
2818:
2817:
2815:
2813:
2809:
2802:
2799:
2796:
2793:
2790:
2789:
2786:
2783:
2781:
2778:
2776:
2773:
2770:
2769:
2766:
2763:
2761:
2758:
2755:
2754:
2751:
2748:
2746:
2743:
2740:
2739:
2737:
2735:
2731:
2727:
2724:
2717:
2712:
2710:
2705:
2703:
2698:
2697:
2694:
2684:
2683:
2676:
2670:
2667:
2665:
2662:
2660:
2657:
2655:
2652:
2650:
2647:
2645:
2642:
2640:
2637:
2635:
2632:
2630:
2627:
2623:
2620:
2618:
2615:
2613:
2610:
2609:
2608:
2605:
2603:
2600:
2596:
2593:
2591:
2588:
2586:
2583:
2582:
2581:
2578:
2576:
2573:
2571:
2568:
2566:
2563:
2561:
2558:
2557:
2555:
2551:
2545:
2542:
2540:
2537:
2535:
2532:
2530:
2527:
2525:
2522:
2520:
2517:
2515:
2512:
2510:
2507:
2506:
2504:
2502:
2498:
2492:
2489:
2487:
2484:
2482:
2479:
2477:
2474:
2472:
2469:
2467:
2464:
2463:
2461:
2459:
2455:
2451:
2443:
2438:
2436:
2431:
2429:
2424:
2423:
2420:
2406:
2400:
2395:
2391:
2385:
2380:
2376:
2370:
2365:
2361:
2352:
2347:
2345:
2340:
2338:
2333:
2332:
2329:
2320:
2316:
2311:
2306:
2302:
2298:
2294:
2289:
2285:
2281:
2276:
2271:
2267:
2263:
2259:
2254:
2250:
2246:
2242:
2238:
2234:
2230:
2224:
2220:
2216:
2211:
2206:
2203:(5): 741–53.
2202:
2198:
2194:
2189:
2185:
2181:
2177:
2173:
2167:
2163:
2159:
2154:
2149:
2145:
2141:
2137:
2132:
2128:
2124:
2120:
2116:
2111:
2106:
2102:
2098:
2094:
2090:
2086:
2082:
2077:
2073:
2069:
2064:
2059:
2055:
2051:
2047:
2042:
2038:
2034:
2030:
2026:
2023:(2): 277–82.
2022:
2018:
2014:
2009:
2005:
2001:
1997:
1993:
1989:
1985:
1981:
1976:
1972:
1968:
1963:
1958:
1953:
1948:
1944:
1940:
1936:
1932:
1928:
1923:
1919:
1915:
1911:
1907:
1903:
1899:
1896:(3): 155–64.
1895:
1891:
1886:
1882:
1878:
1873:
1868:
1864:
1860:
1856:
1852:
1848:
1843:
1839:
1835:
1831:
1829:9780123646002
1825:
1821:
1817:
1813:
1809:
1804:
1800:
1796:
1792:
1788:
1784:
1780:
1775:
1771:
1767:
1763:
1759:
1756:(3): 151–81.
1755:
1751:
1746:
1742:
1738:
1734:
1730:
1726:
1722:
1717:
1716:
1711:
1702:
1698:
1693:
1688:
1683:
1678:
1674:
1670:
1666:
1662:
1658:
1651:
1648:
1643:
1639:
1634:
1629:
1626:(6): 919–35.
1625:
1621:
1617:
1610:
1607:
1602:
1598:
1593:
1588:
1584:
1580:
1576:
1569:
1566:
1561:
1557:
1553:
1549:
1545:
1541:
1537:
1530:
1527:
1522:
1518:
1514:
1510:
1505:
1504:11392/2066612
1500:
1496:
1492:
1488:
1484:
1476:
1474:
1470:
1465:
1459:
1456:
1451:
1447:
1443:
1439:
1435:
1431:
1423:
1420:
1415:
1411:
1405:
1402:
1397:
1393:
1387:
1384:
1380:
1376:
1371:
1369:
1367:
1363:
1359:
1355:
1350:
1348:
1346:
1342:
1335:
1333:
1331:
1327:
1322:
1321:development.
1320:
1316:
1312:
1308:
1300:
1298:
1297:progression.
1296:
1292:
1288:
1284:
1276:
1274:
1272:
1268:
1264:
1260:
1252:
1250:
1248:
1245:
1241:
1237:
1225:
1220:
1216:
1212:
1209:
1205:
1198:
1196:
1193:
1189:
1185:
1181:
1178:
1174:
1170:
1163:
1161:
1157:
1151:
1147:
1144:
1138:
1136:
1132:
1128:
1124:
1118:
1114:
1111:
1107:
1100:
1098:
1094:
1088:
1084:
1081:
1075:
1073:
1069:
1065:
1061:
1055:
1051:
1048:
1046:RefSeq (mRNA)
1044:
1037:
1036:
1031:
1027:
1024:
1018:
1017:
1012:
1008:
1005:
1003:
999:
992:
991:
986:
982:
979:
973:
972:
967:
963:
960:
958:
954:
947:
946:
941:
937:
934:
928:
927:
922:
918:
915:
913:
909:
906:
903:
901:
898:
894:
891:
887:
883:
876:
872:
867:
861:
858:
856:
853:
851:
848:
846:
843:
841:
838:
836:
833:
831:
830:axon guidance
828:
826:
823:
821:
818:
816:
813:
811:
808:
806:
805:viral process
803:
801:
798:
796:
793:
791:
788:
786:
783:
781:
778:
776:
775:cell adhesion
773:
771:
768:
766:
763:
761:
758:
756:
753:
751:
748:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
717:
715:
712:
711:
705:
702:
700:
697:
695:
692:
690:
687:
685:
682:
680:
677:
675:
672:
670:
667:
665:
662:
661:
659:
656:
655:
649:
646:
644:
641:
639:
636:
634:
631:
629:
626:
625:
623:
620:
619:
616:
615:Gene ontology
612:
608:
596:
591:
587:
580:
575:
572:
570:
566:
558:
553:
542:
538:
534:
530:
526:
522:
519:hair follicle
518:
514:
510:
506:
505:
502:
498:
493:
490:
481:hair follicle
480:
476:
472:
468:
464:
460:
456:
452:
448:
444:
443:
440:
436:
431:
428:
427:
424:
422:
418:
416:
415:
411:
410:
407:
405:
401:
397:
393:
389:
381:
376:
372:
368:
363:
353:
349:
342:
335:
329:
322:
314:
310:
306:
301:
297:
292:
288:
280:
275:
271:
267:
262:
252:
248:
241:
234:
228:
221:
217:
211:
207:
203:
198:
194:
189:
185:
181:
177:
173:
169:
165:
161:
157:
153:
149:
145:
137:
132:
125:
120:
115:
104:
102:
98:
94:
90:
86:
82:
78:
72:
67:
64:
63:
59:
56:
49:
45:
40:
36:
32:
27:
22:
16:
5665:expanding it
5650:
5635:
5624:Cerebrolysin
5620:
5594:Pleiotrophin
5550:Interleukins
5463:
5444:
5414:
5333:Fruquintinib
5323:Cabozantinib
5304:
5294:
5252:
5216:Lestaurtinib
5167:
5147:
5115:Lestaurtinib
5066:
5056:
5037:Antagonists:
5036:
4970:Deoxygedunin
4925:3,7,8,2'-THF
4916:
4895:
4886:Against NGF:
4885:
4882:
4838:Against NGF:
4837:
4830:
4827:
4790:Lestaurtinib
4741:
4731:
4725:Testosterone
4707:Antagonists:
4706:
4656:
4556:
4541:
4516:
4497:
4487:
4466:
4456:
4435:
4425:
4404:
4389:
4349:
4264:
4232:
4211:
4202:Against NGF:
4201:
4198:
4154:Against NGF:
4153:
4150:
4144:Testosterone
4126:Antagonists:
4125:
4075:
4045:
4006:
3981:
3970:
3947:Teprotumumab
3908:
3878:
3837:
3786:Ficlatuzumab
3781:Emibetuzumab
3777:
3731:JNJ-38877605
3701:Cabozantinib
3672:
3662:
3651:Fosgonimeton
3646:
3621:
3563:
3541:
3482:
3465:Infigratinib
3461:
3446:
3349:
3266:
3200:Betacellulin
3196:
3179:Seribantumab
3165:
3142:
3101:
3066:
3060:Unknown/none
3059:
3055:
2989:
2914:
2873:Betacellulin
2868:Amphiregulin
2863:
2855:(ErbB1/HER1)
2819:
2791:
2771:
2757:Antagonists:
2756:
2741:
2734:Angiopoietin
2679:
2404:
2389:
2374:
2300:
2296:
2265:
2261:
2232:
2228:
2200:
2196:
2178:(3): 791–7.
2175:
2171:
2146:(3): 403–4.
2143:
2139:
2084:
2080:
2053:
2049:
2020:
2016:
1987:
1983:
1934:
1930:
1893:
1889:
1854:
1850:
1811:
1807:
1782:
1778:
1753:
1749:
1724:
1720:
1664:
1660:
1650:
1623:
1619:
1609:
1582:
1578:
1568:
1543:
1539:
1529:
1486:
1482:
1458:
1433:
1429:
1422:
1413:
1404:
1395:
1386:
1328:, mediating
1323:
1319:optic chiasm
1304:
1301:Interactions
1280:
1256:
1243:
1235:
1234:
1160:NP_001355228
1153:
1135:NP_001358987
1131:NP_001358986
1127:NP_001358985
1120:
1097:NM_001368299
1090:
1072:NM_001372058
1068:NM_001372057
1064:NM_001372056
1057:
1033:
1014:
988:
969:
943:
924:
904:
899:
785:angiogenesis
539:vas deferens
419:
412:
277:106,535,662
264:106,489,745
139:External IDs
74:
15:
5584:Oncomodulin
5448:Aflibercept
5438:Ranibizumab
5433:Ramucirumab
5423:Bevacizumab
5415:Antibodies:
5373:Regorafenib
5313:Altiratinib
5226:ONO-5390556
5196:Entrectinib
5171:Altiratinib
5125:ONO-5390556
5095:Entrectinib
5070:Altiratinib
4856:Frunevetmab
4828:Antibodies:
4805:ONO-5390556
4770:Entrectinib
4745:Altiratinib
4700:Tavilermide
4595:Quizartinib
4534:SCF (c-Kit)
4358:Ramucirumab
4350:Antibodies:
4323:Quizartinib
4273:Avapritinib
4236:Becaplermin
4172:Frunevetmab
4151:Antibodies:
4054:Trofinetide
3985:Dusigitumab
3982:Antibodies:
3937:Robatumumab
3927:Figitumumab
3922:Dalotuzumab
3917:Cixutumumab
3909:Antibodies:
3801:Rilotumumab
3796:Onartuzumab
3791:Flanvotumab
3778:Antibodies:
3746:PF-04217903
3676:Altiratinib
3639:HGF (c-Met)
3542:Antibodies:
3447:Antibodies:
3169:Duligotumab
3166:Antibodies:
3080:Trastuzumab
3070:Ertumaxomab
3067:Antibodies:
3038:Zalutumumab
3033:Panitumumab
3028:Nimotuzumab
3023:Necitumumab
3013:Imgatuzumab
2990:Antibodies:
2973:Osimertinib
2938:Dacomitinib
2833:Dapiclermin
2792:Antibodies:
2775:Altiratinib
2669:Wnt protein
2654:Somatomedin
2357:PDB gallery
2056:(1): 9–19.
1814:: 177–244.
1779:Development
1273:receptors.
117:Identifiers
5704:Categories
5403:Vandetanib
5368:Rebastinib
5363:Pegaptanib
5353:Nintedanib
5343:Lenvatinib
5308:Agerafenib
5261:Ripretinib
5186:CH-7057288
5085:CH-7057288
4950:7,8,3'-THF
4945:7,8,2'-THF
4871:Ranevetmab
4861:Fulranumab
4815:Rebastinib
4760:CH-7057288
4675:Cenegermin
4560:Agerafenib
4520:Agerafenib
4501:Vandetanib
4470:Vandetanib
4439:Vandetanib
4408:Vandetanib
4353:Olaratumab
4328:Ripretinib
4308:Nintedanib
4293:Lenvatinib
4283:Crenolanib
4268:Agerafenib
4187:Ranevetmab
4177:Fulranumab
4094:Cenegermin
4068:LNGF (p75)
3990:Xentuzumab
3952:Xentuzumab
3897:NVP-AEW541
3892:NVP-ADW742
3887:Linsitinib
3882:BMS-754807
3867:Mecasermin
3766:Tivantinib
3756:PHA-665752
3751:PF-2341066
3721:Golvatinib
3711:Crizotinib
3706:Capmatinib
3696:BMS-777607
3691:Amuvatinib
3567:Ersofermin
3530:Sprifermin
3486:Ersofermin
3435:Sprifermin
3425:Repifermin
3420:Palifermin
3353:Ersofermin
3332:Velafermin
3317:Repifermin
3270:Ersofermin
3189:ErbB4/HER4
3174:Patritumab
3135:ErbB3/HER3
3115:Mubritinib
3075:Pertuzumab
3048:ErbB2/HER2
2978:Vandetanib
2933:Canertinib
2928:Brigatinib
2923:Agerafenib
2903:Nepidermin
2898:Murodermin
2888:Epiregulin
2843:EGF (ErbB)
2801:Nesvacumab
2795:Evinacumab
2785:Rebastinib
2726:modulators
2649:Semaphorin
2634:Interferon
2607:Endothelin
1727:: 309–45.
1381:, May 2017
1360:, May 2017
1336:References
1285:-positive
527:right lung
423:(ortholog)
378:8,711,242
365:8,667,434
160:HomoloGene
5655:on human
5428:Icrucumab
5408:WHI-P 154
5398:Tivozanib
5393:Toceranib
5388:Sunitinib
5383:Sorafenib
5378:Semaxanib
5358:Pazopanib
5348:Motesanib
5338:Lapatinib
5328:Cediranib
5266:Telbermin
5253:Agonists:
5201:GZ-389988
5181:CE-245677
5148:Agonists:
5100:GZ-389988
5080:CE-245677
4980:Diosmetin
4917:Agonists:
4883:Aptamers:
4876:Tanezumab
4851:Fasinumab
4795:Milciclib
4775:GZ-389988
4755:CE-245677
4657:Agonists:
4610:Toceranib
4605:Sunitinib
4600:Sorafenib
4590:Pazopanib
4585:Nilotinib
4580:Masitinib
4570:Dasatinib
4542:Agonists:
4488:Agonists:
4457:Agonists:
4426:Agonists:
4398:Liatermin
4390:Agonists:
4373:RET (GFL)
4363:Tovetumab
4343:Toceranib
4338:Sorafenib
4333:Sunitinib
4318:Radotinib
4313:Pazopanib
4303:Motesanib
4298:Masitinib
4233:Agonists:
4199:Aptamers:
4192:Tanezumab
4167:Fasinumab
4076:Agonists:
3932:Ganitumab
3852:IGF-1 LR3
3771:Volitinib
3726:INCB28060
3716:Foretinib
3622:Agonists:
3606:Trafermin
3564:Agonists:
3545:Burosumab
3535:Trafermin
3483:Agonists:
3450:Aprutumab
3440:Trafermin
3402:10 (KGF2)
3350:Agonists:
3327:Trafermin
3307:10 (KGF2)
3267:Agonists:
3197:Agonists:
3143:Agonists:
3125:Tucatinib
3120:Neratinib
3110:Lapatinib
3018:Matuzumab
3008:Futuximab
2993:Cetuximab
2983:WHI-P 154
2968:Neratinib
2963:Lapatinib
2953:Grandinin
2948:Gefitinib
2943:Erlotinib
2820:Agonists:
2780:CE-245677
2742:Agonists:
2680:see also
2560:Adipokine
2110:1807/9444
1918:205014301
1236:Ephrin-B2
1156:NP_034241
1123:NP_004084
1093:NM_010111
1060:NM_004093
890:Orthologs
531:left lung
168:GeneCards
5610:instead)
5599:Renalase
5560:instead)
5531:instead)
5478:instead)
5318:Axitinib
5287:D (FIGF)
5231:PLX-7486
5221:ONO-4474
5176:AZD-6918
5130:PLX-7486
5120:ONO-4474
5075:AZD-6918
5057:Ligands:
4975:Deprenyl
4935:7,3'-DHF
4866:MEDI-578
4846:ASP-6294
4810:PLX-7486
4800:ONO-4474
4750:AZD-6918
4710:ALE-0540
4631:instead.
4575:Imatinib
4565:Axitinib
4545:Ancestim
4510:Unsorted
4288:Imatinib
4278:Axitinib
4182:MEDI-578
4162:ASP-6294
4129:ALE-0540
3971:Agonists
3912:AVE-1642
3838:Agonists
3761:SU-11274
3647:Agonists
3625:FGF15/19
3615:Unsorted
3580:2 (bFGF)
3499:2 (bFGF)
3366:2 (bFGF)
3283:2 (bFGF)
3105:Afatinib
3056:Agonists
2958:Icotinib
2918:Afatinib
2864:Agonists
2602:Cytokine
2017:Genomics
1910:11256076
1881:11128993
1838:10730216
1799:10207129
1701:15998730
1642:12971893
1521:24986454
1513:25205602
1377:–
1356:–
1307:interact
1253:Function
1208:Wikidata
869:Sources:
669:membrane
5487:Ephrins
5191:DS-6051
5090:DS-6051
4995:LM22A-4
4985:DMAQ-B1
4940:7,8-DHF
4920:3,7-DHF
4889:RBM-004
4834:GBR-900
4765:DS-6051
4735:VM-902A
4205:RBM-004
3902:OSl-906
3862:Insulin
3741:MK-2461
3686:AMG-458
2823:Axokine
2450:ligands
2319:9920925
2284:9883737
2249:9718367
2219:9630219
2184:9533549
2162:9267020
2127:4349898
2119:8878483
2089:Bibcode
2072:8755474
2037:8660976
2004:8559144
1971:7534404
1939:Bibcode
1872:1692797
1770:9576626
1741:9530499
1692:1169237
1669:Bibcode
1601:9195962
1560:8559144
1450:7833926
1379:Ensembl
1358:Ensembl
1240:protein
1002:UniProt
957:Ensembl
896:Species
875:QuickGO
398:pattern
256:13q33.3
124:Aliases
5457:Others
5151:BNN-20
5040:ANA-12
4965:BNN-20
4685:DHEA-S
4670:BNN-27
4665:BNN-20
4104:DHEA-S
4089:BNN-27
4084:BNN-20
4000:Others
3205:Epigen
2883:Epigen
2501:Ephrin
2317:
2282:
2262:Neuron
2247:
2217:
2182:
2160:
2125:
2117:
2081:Nature
2070:
2050:Neuron
2035:
2002:
1969:
1959:
1916:
1908:
1879:
1869:
1836:
1826:
1797:
1768:
1739:
1699:
1689:
1640:
1620:Neuron
1599:
1558:
1519:
1511:
1448:
1277:Cancer
1259:ephrin
1194:search
1192:PubMed
1035:P52800
1016:P52799
912:Entrez
569:BioGPS
477:nipple
156:105097
148:600527
5659:is a
5606:(see
5556:(see
5527:(see
5474:(see
5206:K252a
5105:K252a
4780:K252a
4720:FX007
4480:GFRα4
4449:GFRα3
4418:GFRα2
4382:GFRα1
4010:IGFBP
3963:IGF-2
3942:R1507
3830:IGF-1
3736:K252a
3556:FGFR4
3475:FGFR3
3342:FGFR2
3259:FGFR1
2639:Kinin
2553:Other
2544:EFNB3
2539:EFNB2
2534:EFNB1
2529:EFNA5
2524:EFNA4
2519:EFNA3
2514:EFNA2
2509:EFNA1
2123:S2CID
1962:42383
1914:S2CID
1517:S2CID
1330:entry
1315:EPHB1
1311:EPHA3
1309:with
1271:EPHA3
1267:EPHB4
1244:EFNB2
1238:is a
945:13642
905:Mouse
900:Human
871:Amigo
421:Mouse
414:Human
361:Start
296:Mouse
260:Start
193:Human
172:EFNB2
131:EFNB2
24:EFNB2
5661:stub
5653:gene
5608:here
5558:here
5529:here
5476:here
5271:VEGF
5245:VEGF
5161:NT-3
5156:DHEA
5140:TrkC
5060:DHEA
5030:TDP6
5010:NT-4
5005:NT-3
4990:HIOC
4960:BDNF
4909:TrkB
4680:DHEA
4649:TrkA
4629:here
4627:See
4620:TGFβ
4225:PDGF
4119:NT-4
4114:NT-3
4099:DHEA
4079:BDNF
2828:CNTF
2812:CNTF
2622:EDN3
2617:EDN2
2612:EDN1
2405:2hle
2390:1kgy
2375:1iko
2315:PMID
2280:PMID
2245:PMID
2215:PMID
2197:Cell
2180:PMID
2158:PMID
2140:Cell
2115:PMID
2068:PMID
2033:PMID
2000:PMID
1967:PMID
1906:PMID
1877:PMID
1834:PMID
1824:ISBN
1795:PMID
1766:PMID
1737:PMID
1697:PMID
1638:PMID
1597:PMID
1556:PMID
1509:PMID
1446:PMID
1313:and
1269:and
1247:gene
926:1948
404:Bgee
352:Band
313:Chr.
251:Band
210:Chr.
164:3019
144:OMIM
101:4UF7
97:3GXU
93:2WO2
89:2VSM
85:2VSK
81:2I85
77:2HLE
58:RCSB
55:PDBe
5025:R13
4695:NGF
4640:Trk
4109:NGF
3821:IGF
3681:AM7
3572:FGF
3491:FGF
3392:),
3390:KGF
3358:FGF
3275:FGF
3250:FGF
2852:EGF
2305:doi
2301:274
2270:doi
2237:doi
2233:111
2205:doi
2148:doi
2105:hdl
2097:doi
2085:383
2058:doi
2025:doi
1992:doi
1957:PMC
1947:doi
1898:doi
1867:PMC
1859:doi
1855:355
1816:doi
1812:196
1787:doi
1783:126
1758:doi
1729:doi
1687:PMC
1677:doi
1665:102
1628:doi
1587:doi
1583:272
1548:doi
1499:hdl
1491:doi
1487:230
1438:doi
1317:in
374:End
273:End
176:OMA
152:MGI
48:PDB
5706::
5519:B3
5517:,
5515:B2
5513:,
5511:B1
5509:,
5507:A5
5505:,
5503:A4
5501:,
5499:A3
5497:,
5495:A2
5493:,
5491:A1
5285:,
5281:,
5277:,
5020:R7
4836:;
4255:,
4251:,
4247:,
4036:,
4032:,
4028:,
4024:,
4020:,
4016:,
3973::
3840::
3649::
3600:19
3598:,
3594:,
3590:,
3586:,
3582:,
3578:,
3519:23
3517:,
3515:18
3513:,
3509:,
3505:,
3501:,
3497:,
3414:22
3412:,
3410:18
3408:,
3406:17
3404:,
3400:,
3396:,
3384:,
3380:,
3376:,
3372:,
3368:,
3364:,
3311:20
3309:,
3305:,
3301:,
3297:,
3293:,
3289:,
3285:,
3281:,
3233:,
3229:,
3225:,
3221:,
3156:,
3152:,
3058::
2866::
2313:.
2299:.
2295:.
2278:.
2266:21
2264:.
2260:.
2243:.
2231:.
2213:.
2201:93
2199:.
2195:.
2174:.
2156:.
2144:90
2142:.
2138:.
2121:.
2113:.
2103:.
2095:.
2083:.
2066:.
2054:17
2052:.
2048:.
2031:.
2021:33
2019:.
2015:.
1998:.
1988:32
1986:.
1982:.
1965:.
1955:.
1945:.
1935:92
1933:.
1929:.
1912:.
1904:.
1892:.
1875:.
1865:.
1853:.
1849:.
1832:.
1822:.
1810:.
1793:.
1781:.
1764:.
1754:77
1752:.
1735:.
1725:21
1723:.
1695:.
1685:.
1675:.
1663:.
1659:.
1636:.
1624:39
1622:.
1618:.
1595:.
1581:.
1577:.
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