183:
208:
1317:
reaching their targets which usually reside within the cell. Similarly, the glycosylation has been shown to bind to growth factors. This allows cancer cells which produce a large amount of MUC1 to concentrate growth factors near their receptors, increasing receptor activity and the growth of cancer cells. MUC1 also prevents the interaction of immune cells with receptors on the cancer cell surface through steric hindrance. This inhibits an anti-tumor immune response.
430:
423:
416:
3654:
214:
40:
1316:
The ability of chemotherapeutic drugs to access the cancer cells is inhibited by the heavy glycosylation in the extracellular domain of MUC1. The glycosylation creates a highly hydrophilic region which prevents hydrophobic chemotherapeutic drugs from passing through. This prevents the drugs from
2402:
Tolcher AW, Ochoa L, Hammond LA, Patnaik A, Edwards T, Takimoto C, Smith L, de Bono J, Schwartz G, Mays T, Jonak ZL, Johnson R, DeWitte M, Martino H, Audette C, Maes K, Chari RV, Lambert JM, Rowinsky EK (January 2003). "Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg
66:
1393:. A SXXXXXSSL motif was identified in MUC1 that is conserved with other beta-catenin binding partners. This interaction was shown to be dependent on cell adhesion. Studies have demonstrated that MUC1 is phosphorylated on a YEKV motif. Phosphorylation of this site has been demonstrated by
1438:
of the same protein antigen product of the MUC1 gene seen in breast cancer. CA 27.29 has enhanced sensitivity and specificity compared to CA 15-3 and is elevated in 30% of patients with low-stage disease and 60 to 70% of patients with advanced-stage breast cancer.
1878:
to search out and destroy cells that display a specific molecule (or marker) of MUC1. MUC1 is found on nearly all epithelial cells, but it is over expressed in cancer cells, and its associated glycans are shorter than those of non-tumor-associated MUC1.
1417:. These proteins are associated with a mesenchymal phenotype, characterized by increased motility and invasiveness. In cancer cells, increased expression of MUC1 promotes cancer cell invasion through beta-catenin, resulting in the initiation of
1229:
into two pieces, the cytoplasmic tail including the transmembrane domain and the extracellular domain. These domains tightly associate in a non-covalent fashion. This tight, non-covalent association is not broken by treatment with
1333:
gene promoter. This results in activation of p21 which results in cell cycle arrest. Association of MUC1 with p53 in cancer results in inhibition of p53-mediated apoptosis and promotion of p53-mediated cell cycle arrest.
1900:
1409:. MUC1 blocks the phosphorylation-dependent degradation of beta-catenin by GSK3B. The result is that increased expression of MUC1 in cancer increases stabilized beta-catenin. This promotes the expression of
1717:
1264:
is a novel glycoform of MUC1. In the cell nucleus, the protein MUC1 regulates the activity of transcription factor complexes that have a documented role in tumor-induced changes of host immunity.
1211:
by a transmembrane domain. Beyond the transmembrane domain is a SEA domain that contains a cleavage site for release of the large extracellular domain. The release of mucins is performed by
1177:
of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by
4555:
1219:) domain, with the number of repeats varying from 20 to 120 in different individuals. These repeats are rich in serine, threonine and proline residues which permits heavy o-glycosylation.
1185:
in the extracellular domain, preventing the pathogen from reaching the cell surface. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
123:, ADMCKD, ADMCKD1, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, mucin 1, cell surface associated, ADTKD2, Ca15-3, Mucin-1
2525:
Li Y, Yu WH, Ren J, Chen W, Huang L, Kharbanda S, Loda M, Kufe D (August 2003). "Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein".
3694:
1870:. The technology could in theory be applied to 90 percent of all known cancers, including prostate and breast cancer, solid and non-solid tumors. This method would activate the
1222:
Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.
1377:. The cytoplasmic tail is then inserted into the mitochondrial outer membrane. Localization of MUC1 to the mitochondria prevents the activation of apoptotic mechanisms.
221:
63:
4545:
1361:. Additionally, MUC1 was shown to increase expression of Bcl-xL. Overexpression of MUC1 in cancer. The presence of free Bcl-2 and Bcl-xL prevents the release of
3282:
Peterson JA, Scallan CD, Ceriani RL, Hamosh M (2002). "Structural and
Functional Aspects of Three Major Glycoproteins of the Human Milk Fat Globule Membrane".
2557:"Transgenic MUC1 interacts with epidermal growth factor receptor and correlates with mitogen-activated protein kinase activation in the mouse mammary gland"
1204:. MUC1 has a core protein mass of 120-225 kDa which increases to 250-500 kDa with glycosylation. It extends 200-500 nm beyond the surface of the cell.
6269:
4525:
144:
689:
5387:
3711:
3687:
3653:
5731:
5118:
3557:
Zhan XX, Zhao B, Diao C, Cao Y, Cheng RC (2015). "Expression of MUC1 and CD176 (Thomsen-Friedenreich antigen) in papillary thyroid carcinomas".
2599:
Pandey P, Kharbanda S, Kufe D (September 1995). "Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein".
5106:
4884:
1576:
5170:
5165:
5111:
4891:
3672:
3633:
3520:
Fessler SP, Wotkowicz MT, Mahanta S, Bamdad C (2009). "MUC1* is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells".
3299:
3176:
2440:"Aberrant control of NF-ΞΊB in cancer permits transcriptional and phenotypic plasticity, to curtail dependence on host tissue: molecular mode"
3085:
Roy LD, Sahraei M, Subramani DB, Besmer D, Nath S, Tinder TL, Bajaj E, Shanmugam K, Lee YY, Hwang SI, Gendler SJ, Mukherjee P (March 2011).
1945:
6294:
6289:
4624:
4550:
3680:
1882:
Because MUC1 is overexpressed (and differently glycosylated) in many cancers it has been investigated as a drug target, e.g. for the MUC1
6108:
5653:
5648:
5643:
5638:
4565:
1562:
2487:
Li Y, Kufe D (February 2001). "The Human DF3/MUC1 carcinoma-associated antigen signals nuclear localization of the catenin p120(ctn)".
1238:
triggers dissociation of the subunits. The cytoplasmic tail of MUC1 is 72 amino acids long and contains several phosphorylation sites.
1082:
1469:
In micropapillary carcinoma of the breast and bladder, MUC1 stains the stroma-facing surface of cell clusters of micropapillary units.
6148:
5618:
2056:
Moncada DM, Kammanadiminiti SJ, Chadee K (July 2003). "Mucin and Toll-like receptors in host defense against intestinal parasites".
1572:
1418:
1329:. This interaction is increased by genotoxic stress. MUC1 and p53 were found to be associated with the p53 response element of the
2833:"The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin"
1963:
Gendler SJ, Lancaster CA, Taylor-Papadimitriou J, Duhig T, Peat N, Burchell J, Pemberton L, Lalani EN, Wilson D (September 1990).
5998:
4854:
3192:
Gaidzik N, Westerlind U, Kunz H (May 2013). "The development of synthetic antitumour vaccines from mucin glycopeptide antigens".
2278:
Julian J, Carson DD (May 2002). "Formation of MUC1 metabolic complex is conserved in tumor-derived and normal epithelial cells".
2223:
1645:
2874:"The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin"
1365:
from mitochondria, thereby preventing apoptosis. MUC1 cytoplasmic tail is shuttled to the mitochondria through interaction with
5422:
4916:
4602:
1932:
1346:
5061:
4597:
1604:
1473:
2669:"The MUC1 oncoprotein activates the anti-apoptotic phosphoinositide 3-kinase/Akt and Bcl-xL pathways in rat 3Y1 fibroblasts"
207:
182:
5558:
5030:
5025:
4970:
4704:
4153:
1609:
1216:
2710:"MUC1 oncoprotein is targeted to mitochondria by heregulin-induced activation of c-Src and the molecular chaperone HSP90"
1928:
5252:
4975:
132:
6245:
5724:
4570:
3385:
1386:
1273:
3317:
Hu XF, Yang E, Li J, Xing PX (2006). "MUC1 cytoplasmic tail: a potential therapeutic target for ovarian carcinoma".
1442:
CA 27.29 levels over 100 U/mL and CA 15-3 levels over 25 U/mL are rare in benign conditions and suggest malignancy.
220:
6235:
5282:
3707:
1895:
1186:
1246:
The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity.
6198:
6158:
4148:
3626:
3005:"MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin"
1842:
1620:
213:
6138:
6113:
5332:
4227:
3605:
2956:"Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin"
1775:
1700:
1693:
599:
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
6304:
5296:
732:
589:
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
5709:
6173:
5717:
4639:
4634:
4629:
4619:
3926:
3854:
1748:
1615:
1235:
1174:
3983:
3901:
3087:"MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition"
2353:"MUC1 limits Helicobacter pylori infection both by steric hindrance and by acting as a releasable decoy"
1226:
2915:"Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling"
5220:
4933:
3619:
3480:
3427:
2628:"Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response"
1660:
1451:
1046:
1042:
1038:
196:
2351:
LindΓ©n SK, Sheng YH, Every AL, Miles KM, Skoog EC, Florin TH, Sutton P, McGuckin MA (October 2009).
119:
6178:
6103:
5990:
5967:
5931:
5903:
5247:
5066:
2751:"Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion"
2316:
Singh PK, Hollingsworth MA (August 2006). "Cell surface-associated mucins in signal transduction".
1567:
1034:
1026:
1022:
1018:
1014:
1010:
1006:
1002:
998:
994:
990:
986:
982:
978:
974:
964:
960:
956:
952:
948:
909:
897:
893:
889:
885:
881:
877:
873:
869:
865:
861:
857:
853:
849:
845:
841:
831:
827:
823:
819:
815:
1650:
6128:
4654:
4388:
3601:
3582:
3545:
3342:
3229:"Phase 1 dose escalation of ONT-10, a therapeutic MUC1 vaccine, in patients with advanced cancer"
2116:
2038:
1785:
1781:
1688:
1583:
156:
2239:"Cell-associated episialin is a complex containing two proteins derived from a common precursor"
1030:
905:
901:
2188:
Hattrup CL, Gendler SJ (2008). "Structure and function of the cell surface (tethered) mucins".
6203:
6032:
3574:
3537:
3508:
3455:
3402:
3371:
3334:
3305:
3295:
3250:
3209:
3172:
3116:
3067:
3026:
2985:
2936:
2895:
2854:
2813:
2772:
2731:
2690:
2649:
2608:
2578:
2534:
2504:
2469:
2420:
2384:
2333:
2295:
2260:
2205:
2170:
2108:
2073:
2030:
1986:
1539:
1534:
112:
56:
3383:
Li Y, Cozzi PJ (2007). "MUC1 is a promising therapeutic target for prostate cancer therapy".
2201:
584:
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6118:
5935:
5888:
5427:
5160:
5081:
4644:
3837:
3763:
3566:
3529:
3498:
3488:
3445:
3435:
3394:
3363:
3326:
3287:
3258:
3240:
3201:
3106:
3098:
3057:
3016:
2975:
2967:
2926:
2885:
2844:
2803:
2762:
2721:
2680:
2639:
2568:
2496:
2459:
2451:
2412:
2374:
2364:
2325:
2287:
2250:
2197:
2160:
2150:
2100:
2065:
2020:
1976:
1867:
1811:
1671:
1665:
429:
422:
415:
300:
231:
17:
6299:
6075:
6047:
5963:
5487:
4023:
4018:
3941:
1709:
1705:
1557:
1548:
1182:
604:
positive regulation of transcription from RNA polymerase II promoter in response to stress
275:
152:
2237:
Ligtenberg MJ, Kruijshaar L, Buijs F, van Meijer M, Litvinov SV, Hilkens J (March 1992).
1965:"Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin"
1189:
identified and characterised the antigen during her work with breast and ovarian tumors.
3484:
3431:
3148:
2455:
6225:
5744:
5272:
4694:
4205:
4008:
3503:
3468:
3450:
3415:
3263:
3228:
3111:
3086:
2464:
2439:
2379:
2352:
1800:
1722:
1520:
1496:
1261:
1201:
3367:
2980:
2955:
2291:
2255:
2238:
2165:
2138:
2069:
1981:
1964:
1476:(MUC1 positive) from cutaneous anaplastic large cell lymphoma (usually MUC1 negative).
1369:. This interaction is induced through phosphorylation of the MUC1 cytoplasmic tail by
623:
618:
613:
608:
603:
598:
593:
588:
583:
578:
573:
557:
552:
547:
542:
537:
532:
527:
522:
517:
512:
507:
502:
486:
481:
476:
471:
39:
6283:
6273:
6230:
6218:
5898:
5242:
4699:
3790:
1871:
1796:
1743:
1738:
1529:
1398:
1250:
1198:
458:
3586:
3549:
3346:
2120:
2042:
1215:. The extracellular domain includes a 20 amino acid variable number tandem repeat (
6143:
6055:
5922:
5752:
5748:
5598:
4906:
4896:
4427:
4393:
3046:"MUC1 alters beta-catenin-dependent tumor formation and promotes cellular invasion"
1655:
1634:
1488:
1390:
1362:
1170:
293:
173:
3021:
3004:
2872:
Li Y, Ren J, Yu W, Li Q, Kuwahara H, Yin L, Carraway KL, Kufe D (September 2001).
3493:
3440:
3291:
3286:. Advances in Experimental Medicine and Biology. Vol. 501. pp. 179β87.
2369:
2139:"MUC1: a multifunctional cell surface component of reproductive tissue epithelia"
579:
regulation of transcription from RNA polymerase II promoter in response to stress
160:
6255:
6250:
6240:
6213:
6183:
6168:
6037:
5893:
5883:
5760:
5608:
5257:
5035:
5010:
4709:
4331:
4257:
3731:
3245:
1950:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1847:
1728:
1587:
1492:
1480:
1298:
3398:
3044:
Schroeder JA, Adriance MC, Thompson MC, Camenisch TD, Gendler SJ (March 2003).
6083:
5538:
5262:
4943:
4684:
4560:
4193:
4188:
4183:
4038:
3822:
3570:
3533:
3330:
2644:
2627:
2329:
2104:
1770:
1629:
1484:
1455:
1414:
1370:
1338:
1208:
190:
140:
3254:
2767:
2750:
6193:
6188:
6163:
6153:
6065:
5377:
5372:
5367:
5357:
5352:
5347:
5342:
2792:"DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7"
2416:
1866:
Using MUC1, vaccines are being tested against a type of blood cancer called
1591:
1500:
1459:
1374:
1254:
653:
393:
314:
259:
246:
148:
3578:
3541:
3512:
3459:
3406:
3375:
3338:
3309:
3213:
3120:
3071:
3062:
3045:
3030:
2971:
2940:
2931:
2914:
2899:
2890:
2873:
2858:
2849:
2832:
2817:
2735:
2726:
2709:
2694:
2685:
2668:
2653:
2582:
2573:
2556:
2538:
2508:
2500:
2473:
2424:
2388:
2337:
2299:
2209:
2174:
2112:
2077:
2034:
2989:
2776:
2612:
2264:
2155:
1990:
6012:
6007:
6002:
5980:
5975:
5953:
5948:
5908:
5683:
5583:
5397:
5382:
4585:
4580:
4488:
4178:
3102:
1833:
1733:
1552:
1410:
1286:
1212:
1178:
1114:
779:
775:
2808:
2791:
6060:
5943:
5740:
5633:
5628:
5623:
5523:
5337:
5327:
5154:
5133:
5128:
5096:
4901:
4821:
4816:
4811:
4806:
4801:
4719:
4412:
4252:
4247:
4242:
4237:
4232:
3703:
3205:
1905:
1901:
List of histologic stains that aid in diagnosis of cutaneous conditions
1883:
1875:
1640:
1435:
1349:. This results in dissociation of Bcl-2-associated death promoter with
761:
718:
2403:
antigen: a phase I, pharmacokinetic, and biologic correlative study".
1125:
89:
85:
6133:
5852:
5812:
5573:
5533:
5518:
5502:
5497:
5477:
5472:
5407:
5215:
5185:
5149:
5140:
4953:
4921:
4785:
4780:
4750:
4729:
4689:
4649:
4515:
4493:
4452:
4376:
4371:
4366:
4361:
4356:
4351:
4220:
4215:
4210:
4158:
4143:
4013:
4003:
3966:
3961:
3879:
3874:
1828:
1822:
1357:. Activation was shown to be dependent on the upstream activation of
1354:
1280:
1095:
675:
482:
RNA polymerase II cis-regulatory region sequence-specific DNA binding
3003:
Huang L, Chen D, Liu D, Yin L, Kharbanda S, Kufe D (November 2005).
2025:
2008:
1405:. This interaction is antagonized by degradation of beta-catenin by
1249:
Overexpression, aberrant intracellular localization, and changes in
614:
negative regulation of transcription by competitive promoter binding
1762:
Apical surface of almost all glandular and ductal epithelial cells:
1197:
MUC1 is a member of the mucin family and encodes a membrane bound,
6027:
6022:
5867:
5862:
5857:
5847:
5842:
5837:
5817:
5802:
5797:
5782:
5769:
5698:
5673:
5593:
5588:
5578:
5568:
5553:
5548:
5543:
5528:
5482:
5467:
5432:
5417:
5412:
5402:
5322:
5317:
5312:
5291:
5287:
5277:
5190:
5091:
5086:
5045:
4995:
4990:
4985:
4980:
4965:
4958:
4938:
4926:
4869:
4864:
4859:
4849:
4844:
4837:
4775:
4765:
4760:
4755:
4745:
4724:
4714:
4679:
4674:
4669:
4664:
4659:
4614:
4609:
4575:
4540:
4535:
4530:
4520:
4508:
4503:
4483:
4478:
4473:
4468:
4422:
4314:
4309:
4128:
4112:
4105:
4100:
4095:
4090:
4085:
4080:
4055:
4033:
4028:
3921:
3847:
3842:
3832:
2708:
Ren J, Bharti A, Raina D, Chen W, Ahmad R, Kufe D (January 2006).
1406:
1402:
1366:
1350:
1258:
1159:
1491:, in which it is restricted to the cell membranes and associated
638:
634:
6208:
6123:
6017:
5832:
5827:
5822:
5807:
5792:
5787:
5777:
5693:
5688:
5678:
5668:
5663:
5658:
5613:
5603:
5563:
5492:
5462:
5457:
5452:
5447:
5442:
5437:
5392:
5362:
5267:
5235:
5230:
5210:
5200:
5195:
5180:
5175:
5076:
5071:
5040:
5020:
5015:
5005:
5000:
4879:
4832:
4792:
4447:
4442:
4437:
4432:
4417:
4408:
4403:
4398:
4383:
4341:
4336:
4326:
4321:
4304:
4299:
4294:
4289:
4284:
4279:
4274:
4269:
4264:
4200:
4173:
4168:
4163:
4138:
4133:
4070:
4065:
4060:
4050:
4045:
3998:
3993:
3988:
3978:
3973:
3956:
3951:
3946:
3936:
3931:
3916:
3911:
3906:
3896:
3891:
3886:
3869:
3864:
3859:
3810:
3778:
3773:
3768:
3751:
3746:
3741:
3736:
2555:
Schroeder JA, Thompson MC, Gardner MM, Gendler SJ (April 2001).
1358:
1304:
1292:
1231:
1166:
136:
5713:
3676:
3615:
438:
5205:
3817:
3805:
3800:
3795:
3785:
3758:
3726:
3662:: Solution structure of the SEA domain of human mucin 1 (MUC1)
3611:
2009:"Mucins in cancer: protection and control of the cell surface"
1718:
Acquired cystic kidney disease-associated renal cell carcinoma
1394:
1342:
1330:
1326:
3416:"A minimal fragment of MUC1 mediates growth of cancer cells"
2790:
Li Y, Chen W, Ren J, Yu WH, Li Q, Yoshida K, Kufe D (2003).
1507:
3469:"MUC1* mediates the growth of human pluripotent stem cells"
3227:
Nemunaitis J, Bedell C, Klucher K, Vo A, Whiting S (2013).
3354:
Leroy X, Buisine MP, Leteurtre E, et al. (2007). "".
2091:
Gendler SJ (July 2001). "MUC1, the renaissance molecule".
594:
negative regulation of cell adhesion mediated by integrin
3467:
Hikita ST, Kosik KS, Clegg DO, Bamdad C (October 2008).
2954:
Li Y, Bharti A, Chen D, Gong J, Kufe D (December 1998).
283:
3157:
Topic
Completed: 1 May 2012. Revised: 18 September 2019
1345:. Phosphorylation of Akt results in phosphorylation of
3414:
Mahanta S, Fessler SP, Park J, Bamdad C (April 2008).
1466:
It is a marker of various types of cancer (see below).
1454:, MUC1 can be identified in a wide range of secretory
1434:
CA 27.29 (aka BR 27.29) and CA 15-3 measure different
1207:
The protein is anchored to the apical surface of many
3171:. London: Greenwich Medical Media. pp. 205β206.
2831:
Li Y, Kuwahara H, Ren J, Wen G, Kufe D (March 2001).
1373:. Src is activated by the EGF receptor family ligand
405:
619:
stimulatory C-type lectin receptor signaling pathway
6096:
6074:
6046:
5989:
5962:
5930:
5921:
5876:
5768:
5759:
5511:
5305:
5054:
4738:
4461:
4121:
3719:
3169:
Manual of diagnostic antibodies for immunohistology
1487:carcinoma deposits, EMA can be used to distinguish
1483:, are more commonly used for the identification of
1060:
947:
923:
814:
1924:
1922:
1920:
2137:Brayman M, Thathiah A, Carson DD (January 2004).
230:
1886:ONT-10, which has had a phase 1 clinical study.
1430:Blood tests: Cancer Antigens (CA) 27.29 and 15-3
1325:MUC1 cytoplasmic tail has been shown to bind to
2749:Yamamoto M, Bharti A, Li Y, Kufe D (May 1997).
2550:
2548:
2520:
2518:
2311:
2309:
1234:, low pH, high salt or boiling. Treatment with
3142:
3140:
3138:
3136:
3134:
3132:
3130:
2594:
2592:
2132:
2130:
2002:
2000:
1499:, in which it is diffusely spread through the
5725:
3688:
3627:
2007:Hollingsworth MA, Swanson BJ (January 2004).
574:positive regulation of histone H4 acetylation
8:
3149:"Stains - Epithelial membrane antigen (EMA)"
1421:which promotes the formation of metastases.
1929:GRCh38: Ensembl release 89: ENSG00000185499
6270:United States National Library of Medicine
5927:
5765:
5732:
5718:
5710:
3695:
3681:
3673:
3634:
3620:
3612:
1253:of this protein have been associated with
944:
811:
649:
454:
271:
168:
74:
3712:list of human clusters of differentiation
3604:at the U.S. National Library of Medicine
3502:
3492:
3449:
3439:
3262:
3244:
3167:Cooper K; Leong AS-Y; Leong JW-M (2003).
3110:
3061:
3020:
2979:
2930:
2889:
2848:
2807:
2766:
2725:
2684:
2667:Raina D, Kharbanda S, Kufe D (May 2004).
2643:
2572:
2463:
2378:
2368:
2254:
2164:
2154:
2024:
1980:
6268:This article incorporates text from the
2202:10.1146/annurev.physiol.70.113006.100659
6038:Structural maintenance of chromosomes 3
3649:
1916:
1169:in humans. Mucin short variant S1 is a
1577:interdigitating dendritic cell sarcoma
29:
2626:Wei X, Xu H, Kufe D (February 2005).
1755:Normal tissues with positive staining
1401:, Src through mediation of EGFR, and
528:integral component of plasma membrane
235:
194:
189:
7:
1513:Diseases with positive MUC1 staining
3233:Journal for Immunotherapy of Cancer
2456:10.20892/j.issn.2095-3941.2017.0029
2243:The Journal of Biological Chemistry
1969:The Journal of Biological Chemistry
1563:Desmoplastic small-round-cell tumor
1479:Although other antibodies, such as
1385:MUC1 cytoplasmic tail was shown to
624:cytokine-mediated signaling pathway
3284:Bioactive Components of Human Milk
2438:Vlahopoulos, SA (15 August 2017).
1057:
920:
789:
766:
742:
723:
699:
680:
477:transcription coregulator activity
410:
371:
309:
288:
25:
6149:Cholesterylester transfer protein
5999:Chondroitin sulfate proteoglycans
2224:"Entrez Gene: SEA Domain of MUC1"
1573:Follicular dendritic cell sarcoma
1419:epithelial-mesenchymal transition
1341:increased the phosphorylation of
3652:
2913:Ren J, Li Y, Kufe D (May 2002).
428:
421:
414:
219:
212:
206:
181:
38:
2093:J. Mammary Gland Biol Neoplasia
1347:Bcl-2-associated death promoter
1605:Anaplastic large-cell lymphoma
1474:anaplastic large cell lymphoma
513:integral component of membrane
439:More reference expression data
394:More reference expression data
345:olfactory zone of nasal mucosa
1:
3368:10.1016/S0242-6498(06)70718-0
3022:10.1158/0008-5472.CAN-05-2474
2489:Biochem. Biophys. Res. Commun
2444:Cancer Biology & Medicine
2292:10.1016/S0006-291X(02)00352-2
2256:10.1016/S0021-9258(18)42677-4
2070:10.1016/S1471-4922(03)00122-3
1982:10.1016/S0021-9258(18)77254-2
1646:Paget's disease of the breast
1610:Diffuse large B-cell lymphoma
204:
3494:10.1371/journal.pone.0003312
3441:10.1371/journal.pone.0002054
3292:10.1007/978-1-4615-1371-1_23
2370:10.1371/journal.ppat.1000617
1862:As a therapeutic drug target
1472:It can distinguish systemic
1144:polymorphic epithelial mucin
6295:Clusters of differentiation
6290:Genes on human chromosome 1
6246:Tumor necrosis factor alpha
3708:clusters of differentiation
3386:Current Cancer Drug Targets
3246:10.1186/2051-1426-1-S1-P240
2190:Annual Review of Physiology
1152:epithelial membrane antigen
18:Epithelial membrane antigen
6321:
6236:Thyroxine-binding proteins
3399:10.2174/156800907780618338
3319:Expert Rev Anticancer Ther
2280:Biochem Biophys Res Commun
1896:Cluster of differentiation
1843:Follicular dendritic cells
1337:Overexpression of MUC1 in
1187:Joyce Taylor-Papadimitriou
6199:Serum amyloid P component
6159:Colony-stimulating factor
3647:
3571:10.1007/s12022-015-9356-9
3534:10.1007/s10549-009-0412-3
3331:10.1586/14737140.6.8.1261
2645:10.1016/j.ccr.2005.01.008
2330:10.1016/j.tcb.2006.07.006
1946:"Human PubMed Reference:"
1621:Primary effusion lymphoma
1129:
1124:
1120:
1113:
1094:
1083:Chr 1: 155.19 β 155.19 Mb
1077:
1064:
971:
940:
927:
838:
807:
796:
792:
773:
769:
760:
749:
745:
730:
726:
717:
706:
702:
687:
683:
674:
659:
652:
648:
632:
457:
453:
436:
413:
404:
391:
378:
374:
321:
312:
282:
274:
270:
253:
240:
203:
180:
171:
167:
130:
127:
117:
110:
105:
82:
77:
60:
55:
50:
46:
37:
32:
6139:B-cell activating factor
6114:Alpha 1-antichymotrypsin
3606:Medical Subject Headings
2768:10.1074/jbc.272.19.12492
1776:Distal convoluted tubule
1701:Hepatocellular carcinoma
1694:Adrenocortical carcinoma
1579:, reticulum cell sarcoma
1381:Promoting tumor invasion
3522:Breast Cancer Res Treat
2417:10.1200/JCO.2003.05.137
2105:10.1023/A:1011379725811
1272:MUC1 has been shown to
1225:MUC1 is cleaved in the
6174:Membrane glycoproteins
3063:10.1038/sj.onc.1206291
2972:10.1128/mcb.18.12.7216
2932:10.1074/jbc.M200436200
2891:10.1074/jbc.C100359200
2850:10.1074/jbc.C000754200
2727:10.1038/sj.onc.1209012
2686:10.1074/jbc.M310538200
2574:10.1074/jbc.M011248200
2501:10.1006/bbrc.2001.4383
2143:Reprod Biol Endocrinol
1749:Solitary fibrous tumor
1616:Plasmablastic lymphoma
1236:sodium dodecyl sulfate
1175:O-linked glycosylation
1140:Mucin short variant S1
533:apical plasma membrane
329:pancreatic ductal cell
61:Human UniProt search:
3356:Annales de Pathologie
2156:10.1186/1477-7827-2-4
2013:Nature Reviews Cancer
1612:(variable expression)
1397:through mediation of
1321:Preventing cell death
1227:endoplasmic reticulum
548:extracellular exosome
361:palpebral conjunctiva
3103:10.1038/onc.2010.526
1661:Renal cell carcinoma
1452:immunohistochemistry
1446:Immunohistochemistry
503:extracellular region
197:Chromosome 1 (human)
78:List of PDB id codes
51:Available structures
6179:Myelin protein zero
6104:Activin and inhibin
5904:Phytohaemagglutinin
3602:MUC1+protein,+human
3485:2008PLoSO...3.3312H
3432:2008PLoSO...3.2054M
3015:(22): 10413β10422.
2809:10.4161/cbt.2.2.282
2679:(20): 20607β20612.
1689:Myoepithelial cells
1568:Epithelioid sarcoma
609:O-glycan processing
553:extracellular space
6272:, which is in the
6129:Asialoglycoprotein
3206:10.1039/c3cs35470a
1769:Breast, including
1668:(epithelial areas)
567:Biological process
496:Cellular component
465:Molecular function
353:buccal mucosa cell
349:lower lobe of lung
337:right uterine tube
6264:
6263:
6204:Sialoglycoprotein
6092:
6091:
6033:Platelet factor 4
5917:
5916:
5707:
5706:
3670:
3669:
3301:978-1-4613-5521-2
3239:(Suppl 1): P240.
3178:978-1-84110-100-2
3153:PathologyOutlines
3097:(12): 1449β1459.
2796:Cancer Biol. Ther
2607:(18): 4000β4003.
1858:
1857:
1848:Perineurial cells
1812:white blood cells
1786:pulmonary alveoli
1681:Negative staining
1540:Pancreatic cancer
1535:Colorectal cancer
1137:
1136:
1133:
1132:
1109:
1108:
1073:
1072:
1054:
1053:
936:
935:
917:
916:
803:
802:
786:
785:
756:
755:
739:
738:
713:
712:
696:
695:
644:
643:
449:
448:
445:
444:
400:
399:
387:
386:
368:
367:
266:
265:
101:
100:
97:
96:
16:(Redirected from
6312:
6119:Apolipoprotein H
5928:
5889:Intrinsic factor
5766:
5734:
5727:
5720:
5711:
3697:
3690:
3683:
3674:
3656:
3636:
3629:
3622:
3613:
3590:
3553:
3516:
3506:
3496:
3463:
3453:
3443:
3410:
3379:
3350:
3313:
3269:
3268:
3266:
3248:
3224:
3218:
3217:
3189:
3183:
3182:
3164:
3158:
3156:
3144:
3125:
3124:
3114:
3082:
3076:
3075:
3065:
3041:
3035:
3034:
3024:
3000:
2994:
2993:
2983:
2951:
2945:
2944:
2934:
2925:(20): 17616β22.
2910:
2904:
2903:
2893:
2884:(38): 35239β42.
2869:
2863:
2862:
2852:
2828:
2822:
2821:
2811:
2787:
2781:
2780:
2770:
2746:
2740:
2739:
2729:
2705:
2699:
2698:
2688:
2664:
2658:
2657:
2647:
2623:
2617:
2616:
2596:
2587:
2586:
2576:
2567:(16): 13057β64.
2552:
2543:
2542:
2522:
2513:
2512:
2484:
2478:
2477:
2467:
2435:
2429:
2428:
2399:
2393:
2392:
2382:
2372:
2363:(10): e1000617.
2348:
2342:
2341:
2318:Trends Cell Biol
2313:
2304:
2303:
2286:(4): 1183β1190.
2275:
2269:
2268:
2258:
2234:
2228:
2227:
2220:
2214:
2213:
2185:
2179:
2178:
2168:
2158:
2134:
2125:
2124:
2088:
2082:
2081:
2058:Trends Parasitol
2053:
2047:
2046:
2028:
2004:
1995:
1994:
1984:
1975:(25): 15286β93.
1960:
1954:
1953:
1942:
1936:
1926:
1868:multiple myeloma
1706:Germ cell tumors
1672:Thymic carcinoma
1666:Synovial sarcoma
1508:
1183:oligosaccharides
1122:
1121:
1105:
1090:
1085:
1068:
1058:
1049:
945:
941:RefSeq (protein)
931:
921:
912:
812:
790:
767:
743:
724:
700:
681:
650:
455:
441:
432:
425:
418:
411:
396:
372:
333:nasal epithelium
317:
315:Top expressed in
310:
289:
272:
262:
249:
238:
223:
216:
210:
199:
185:
169:
163:
161:MUC1 - orthologs
122:
115:
92:
75:
69:
48:
47:
42:
30:
21:
6320:
6319:
6315:
6314:
6313:
6311:
6310:
6309:
6280:
6279:
6265:
6260:
6088:
6070:
6042:
5985:
5958:
5913:
5872:
5755:
5738:
5708:
5703:
5507:
5301:
5050:
4734:
4457:
4117:
3715:
3701:
3671:
3666:
3663:
3657:
3643:
3640:
3598:
3593:
3556:
3519:
3466:
3413:
3382:
3353:
3316:
3302:
3281:
3277:
3275:Further reading
3272:
3226:
3225:
3221:
3200:(10): 4421β42.
3191:
3190:
3186:
3179:
3166:
3165:
3161:
3146:
3145:
3128:
3084:
3083:
3079:
3043:
3042:
3038:
3002:
3001:
2997:
2966:(12): 7216β24.
2960:Mol. Cell. Biol
2953:
2952:
2948:
2912:
2911:
2907:
2871:
2870:
2866:
2830:
2829:
2825:
2789:
2788:
2784:
2761:(19): 12492β4.
2748:
2747:
2743:
2707:
2706:
2702:
2666:
2665:
2661:
2625:
2624:
2620:
2598:
2597:
2590:
2554:
2553:
2546:
2527:Mol. Cancer Res
2524:
2523:
2516:
2486:
2485:
2481:
2437:
2436:
2432:
2401:
2400:
2396:
2350:
2349:
2345:
2315:
2314:
2307:
2277:
2276:
2272:
2236:
2235:
2231:
2222:
2221:
2217:
2187:
2186:
2182:
2136:
2135:
2128:
2090:
2089:
2085:
2055:
2054:
2050:
2026:10.1038/nrc1251
2006:
2005:
1998:
1962:
1961:
1957:
1944:
1943:
1939:
1927:
1918:
1914:
1892:
1864:
1859:
1801:apocrine glands
1793:Salivary glands
1710:choriocarcinoma
1558:Choriocarcinoma
1549:Carcinoid tumor
1521:Adenocarcinomas
1448:
1432:
1427:
1425:Diagnostic uses
1383:
1323:
1314:
1270:
1244:
1195:
1173:with extensive
1162:encoded by the
1126:View/Edit Human
1103:
1088:
1081:
1078:Location (UCSC)
1066:
1045:
1041:
1037:
1033:
1029:
1025:
1021:
1017:
1013:
1009:
1005:
1001:
997:
993:
989:
985:
981:
977:
973:
967:
963:
959:
955:
951:
929:
908:
904:
900:
896:
892:
888:
884:
880:
876:
872:
868:
864:
860:
856:
852:
848:
844:
840:
834:
830:
826:
822:
818:
778:
733:ENSG00000185499
628:
562:
558:plasma membrane
491:
472:protein binding
437:
427:
426:
420:
419:
392:
383:
364:
359:
355:
351:
347:
343:
339:
335:
331:
327:
313:
257:
244:
236:
226:
225:
224:
217:
195:
172:Gene location (
131:
118:
111:
84:
62:
28:
23:
22:
15:
12:
11:
5:
6318:
6316:
6308:
6307:
6305:Human proteins
6302:
6297:
6292:
6282:
6281:
6262:
6261:
6259:
6258:
6253:
6248:
6243:
6238:
6233:
6228:
6226:Thrombopoietin
6223:
6222:
6221:
6216:
6211:
6201:
6196:
6191:
6186:
6181:
6176:
6171:
6166:
6161:
6156:
6151:
6146:
6141:
6136:
6131:
6126:
6121:
6116:
6111:
6106:
6100:
6098:
6094:
6093:
6090:
6089:
6087:
6086:
6080:
6078:
6072:
6071:
6069:
6068:
6063:
6058:
6052:
6050:
6044:
6043:
6041:
6040:
6035:
6030:
6025:
6020:
6015:
6010:
6005:
5995:
5993:
5987:
5986:
5984:
5983:
5978:
5972:
5970:
5960:
5959:
5957:
5956:
5951:
5946:
5940:
5938:
5925:
5919:
5918:
5915:
5914:
5912:
5911:
5906:
5901:
5896:
5891:
5886:
5880:
5878:
5874:
5873:
5871:
5870:
5865:
5860:
5855:
5850:
5845:
5840:
5835:
5830:
5825:
5820:
5815:
5810:
5805:
5800:
5795:
5790:
5785:
5780:
5774:
5772:
5763:
5757:
5756:
5745:glycoconjugate
5739:
5737:
5736:
5729:
5722:
5714:
5705:
5704:
5702:
5701:
5696:
5691:
5686:
5681:
5676:
5671:
5666:
5661:
5656:
5651:
5646:
5641:
5636:
5631:
5626:
5621:
5616:
5611:
5606:
5601:
5596:
5591:
5586:
5581:
5576:
5571:
5566:
5561:
5556:
5551:
5546:
5541:
5536:
5531:
5526:
5521:
5515:
5513:
5509:
5508:
5506:
5505:
5500:
5495:
5490:
5485:
5480:
5475:
5470:
5465:
5460:
5455:
5450:
5445:
5440:
5435:
5430:
5425:
5420:
5415:
5410:
5405:
5400:
5395:
5390:
5385:
5380:
5375:
5370:
5365:
5360:
5355:
5350:
5345:
5340:
5335:
5330:
5325:
5320:
5315:
5309:
5307:
5303:
5302:
5300:
5299:
5294:
5285:
5280:
5275:
5270:
5265:
5260:
5255:
5250:
5245:
5240:
5239:
5238:
5233:
5223:
5218:
5213:
5208:
5203:
5198:
5193:
5188:
5183:
5178:
5173:
5168:
5163:
5158:
5152:
5143:
5138:
5137:
5136:
5131:
5121:
5116:
5115:
5114:
5109:
5099:
5094:
5089:
5084:
5079:
5074:
5069:
5064:
5058:
5056:
5052:
5051:
5049:
5048:
5043:
5038:
5033:
5028:
5023:
5018:
5013:
5008:
5003:
4998:
4993:
4988:
4983:
4978:
4973:
4968:
4963:
4962:
4961:
4956:
4946:
4941:
4936:
4931:
4930:
4929:
4924:
4919:
4909:
4904:
4899:
4894:
4889:
4888:
4887:
4882:
4872:
4867:
4862:
4857:
4852:
4847:
4842:
4841:
4840:
4835:
4825:
4819:
4814:
4809:
4804:
4795:
4790:
4789:
4788:
4783:
4778:
4768:
4763:
4758:
4753:
4748:
4742:
4740:
4736:
4735:
4733:
4732:
4727:
4722:
4717:
4712:
4707:
4702:
4697:
4692:
4687:
4682:
4677:
4672:
4667:
4662:
4657:
4652:
4647:
4642:
4637:
4632:
4627:
4622:
4617:
4612:
4607:
4606:
4605:
4600:
4590:
4589:
4588:
4583:
4573:
4568:
4563:
4558:
4553:
4548:
4543:
4538:
4533:
4528:
4523:
4518:
4513:
4512:
4511:
4506:
4496:
4491:
4486:
4481:
4476:
4471:
4465:
4463:
4459:
4458:
4456:
4455:
4450:
4445:
4440:
4435:
4430:
4425:
4420:
4415:
4406:
4401:
4396:
4391:
4386:
4381:
4380:
4379:
4374:
4369:
4364:
4359:
4354:
4344:
4339:
4334:
4329:
4324:
4319:
4318:
4317:
4312:
4302:
4297:
4292:
4287:
4282:
4277:
4272:
4267:
4262:
4261:
4260:
4255:
4250:
4245:
4240:
4235:
4225:
4224:
4223:
4218:
4213:
4203:
4198:
4197:
4196:
4191:
4186:
4176:
4171:
4166:
4161:
4156:
4151:
4146:
4141:
4136:
4131:
4125:
4123:
4119:
4118:
4116:
4115:
4110:
4109:
4108:
4103:
4098:
4093:
4088:
4083:
4073:
4068:
4063:
4058:
4053:
4048:
4043:
4042:
4041:
4036:
4031:
4026:
4016:
4011:
4006:
4001:
3996:
3991:
3986:
3981:
3976:
3971:
3970:
3969:
3964:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3884:
3883:
3882:
3877:
3867:
3862:
3857:
3852:
3851:
3850:
3845:
3840:
3835:
3825:
3820:
3815:
3814:
3813:
3803:
3798:
3793:
3788:
3783:
3782:
3781:
3776:
3771:
3761:
3756:
3755:
3754:
3749:
3744:
3739:
3734:
3723:
3721:
3717:
3716:
3702:
3700:
3699:
3692:
3685:
3677:
3668:
3667:
3665:
3664:
3658:
3651:
3648:
3645:
3644:
3641:
3639:
3638:
3631:
3624:
3616:
3610:
3609:
3597:
3596:External links
3594:
3592:
3591:
3559:Endocr. Pathol
3554:
3517:
3464:
3411:
3380:
3351:
3325:(8): 1261β71.
3314:
3300:
3278:
3276:
3273:
3271:
3270:
3219:
3184:
3177:
3159:
3126:
3077:
3056:(9): 1324β32.
3036:
2995:
2946:
2905:
2864:
2823:
2782:
2741:
2700:
2659:
2638:(2): 167β178.
2618:
2588:
2544:
2533:(10): 765β75.
2514:
2479:
2450:(3): 254β270.
2430:
2405:J. Clin. Oncol
2394:
2343:
2324:(9): 467β476.
2305:
2270:
2229:
2215:
2180:
2126:
2099:(3): 339β353.
2083:
2064:(7): 305β311.
2048:
1996:
1955:
1937:
1915:
1913:
1910:
1909:
1908:
1903:
1898:
1891:
1888:
1863:
1860:
1856:
1855:
1851:
1850:
1845:
1839:
1838:
1837:
1836:
1831:
1825:
1816:
1815:
1807:
1806:
1805:
1804:
1794:
1791:
1788:
1779:
1773:
1764:
1763:
1759:
1758:
1756:
1752:
1751:
1746:
1741:
1736:
1731:
1726:
1723:Leiomyosarcoma
1720:
1714:
1713:
1703:
1697:
1696:
1691:
1685:
1684:
1682:
1677:
1676:
1675:
1669:
1663:
1658:
1653:
1648:
1643:
1638:
1632:
1626:
1625:
1624:
1623:
1618:
1613:
1607:
1599:
1598:
1595:
1580:
1570:
1565:
1560:
1555:
1545:
1544:
1543:
1542:
1537:
1532:
1524:
1523:
1517:
1516:
1514:
1506:
1505:
1504:
1497:adenocarcinoma
1477:
1470:
1467:
1462:equivalents:
1447:
1444:
1431:
1428:
1426:
1423:
1382:
1379:
1322:
1319:
1313:
1312:Role in cancer
1310:
1309:
1308:
1302:
1296:
1290:
1284:
1269:
1266:
1262:tumour antigen
1243:
1240:
1202:phosphoprotein
1194:
1191:
1142:, also called
1135:
1134:
1131:
1130:
1128:
1118:
1117:
1111:
1110:
1107:
1106:
1101:
1099:
1092:
1091:
1086:
1079:
1075:
1074:
1071:
1070:
1062:
1061:
1055:
1052:
1051:
1047:NP_001037856.1
1043:NP_001191225.1
1039:NP_001191217.1
969:
968:
942:
938:
937:
934:
933:
925:
924:
918:
915:
914:
836:
835:
809:
805:
804:
801:
800:
794:
793:
787:
784:
783:
771:
770:
764:
758:
757:
754:
753:
747:
746:
740:
737:
736:
728:
727:
721:
715:
714:
711:
710:
704:
703:
697:
694:
693:
685:
684:
678:
672:
671:
666:
661:
657:
656:
646:
645:
642:
641:
630:
629:
627:
626:
621:
616:
611:
606:
601:
596:
591:
586:
581:
576:
570:
568:
564:
563:
561:
560:
555:
550:
545:
540:
535:
530:
525:
520:
515:
510:
505:
499:
497:
493:
492:
490:
489:
484:
479:
474:
468:
466:
462:
461:
451:
450:
447:
446:
443:
442:
434:
433:
408:
402:
401:
398:
397:
389:
388:
385:
384:
382:
379:
376:
375:
369:
366:
365:
363:
362:
358:
357:gastric mucosa
354:
350:
346:
342:
338:
334:
330:
326:
322:
319:
318:
306:
305:
297:
286:
280:
279:
276:RNA expression
268:
267:
264:
263:
255:
251:
250:
242:
239:
234:
228:
227:
218:
211:
205:
201:
200:
193:
187:
186:
178:
177:
165:
164:
129:
125:
124:
116:
108:
107:
103:
102:
99:
98:
95:
94:
80:
79:
71:
70:
59:
53:
52:
44:
43:
35:
34:
26:
24:
14:
13:
10:
9:
6:
4:
3:
2:
6317:
6306:
6303:
6301:
6298:
6296:
6293:
6291:
6288:
6287:
6285:
6278:
6277:
6275:
6274:public domain
6271:
6257:
6254:
6252:
6249:
6247:
6244:
6242:
6239:
6237:
6234:
6232:
6231:Thyroglobulin
6229:
6227:
6224:
6220:
6219:Glycophorin C
6217:
6215:
6212:
6210:
6207:
6206:
6205:
6202:
6200:
6197:
6195:
6192:
6190:
6187:
6185:
6182:
6180:
6177:
6175:
6172:
6170:
6167:
6165:
6162:
6160:
6157:
6155:
6152:
6150:
6147:
6145:
6142:
6140:
6137:
6135:
6132:
6130:
6127:
6125:
6122:
6120:
6117:
6115:
6112:
6110:
6107:
6105:
6102:
6101:
6099:
6095:
6085:
6082:
6081:
6079:
6077:
6073:
6067:
6064:
6062:
6059:
6057:
6054:
6053:
6051:
6049:
6045:
6039:
6036:
6034:
6031:
6029:
6026:
6024:
6021:
6019:
6016:
6014:
6011:
6009:
6006:
6004:
6000:
5997:
5996:
5994:
5992:
5988:
5982:
5979:
5977:
5974:
5973:
5971:
5969:
5965:
5961:
5955:
5952:
5950:
5947:
5945:
5942:
5941:
5939:
5937:
5933:
5929:
5926:
5924:
5923:Proteoglycans
5920:
5910:
5907:
5905:
5902:
5900:
5899:Peptidoglycan
5897:
5895:
5892:
5890:
5887:
5885:
5882:
5881:
5879:
5875:
5869:
5866:
5864:
5861:
5859:
5856:
5854:
5851:
5849:
5846:
5844:
5841:
5839:
5836:
5834:
5831:
5829:
5826:
5824:
5821:
5819:
5816:
5814:
5811:
5809:
5806:
5804:
5801:
5799:
5796:
5794:
5791:
5789:
5786:
5784:
5781:
5779:
5776:
5775:
5773:
5771:
5767:
5764:
5762:
5758:
5754:
5753:glycopeptides
5750:
5749:glycoproteins
5746:
5742:
5735:
5730:
5728:
5723:
5721:
5716:
5715:
5712:
5700:
5697:
5695:
5692:
5690:
5687:
5685:
5682:
5680:
5677:
5675:
5672:
5670:
5667:
5665:
5662:
5660:
5657:
5655:
5652:
5650:
5647:
5645:
5642:
5640:
5637:
5635:
5632:
5630:
5627:
5625:
5622:
5620:
5617:
5615:
5612:
5610:
5607:
5605:
5602:
5600:
5597:
5595:
5592:
5590:
5587:
5585:
5582:
5580:
5577:
5575:
5572:
5570:
5567:
5565:
5562:
5560:
5557:
5555:
5552:
5550:
5547:
5545:
5542:
5540:
5537:
5535:
5532:
5530:
5527:
5525:
5522:
5520:
5517:
5516:
5514:
5510:
5504:
5501:
5499:
5496:
5494:
5491:
5489:
5486:
5484:
5481:
5479:
5476:
5474:
5471:
5469:
5466:
5464:
5461:
5459:
5456:
5454:
5451:
5449:
5446:
5444:
5441:
5439:
5436:
5434:
5431:
5429:
5426:
5424:
5421:
5419:
5416:
5414:
5411:
5409:
5406:
5404:
5401:
5399:
5396:
5394:
5391:
5389:
5386:
5384:
5381:
5379:
5376:
5374:
5371:
5369:
5366:
5364:
5361:
5359:
5356:
5354:
5351:
5349:
5346:
5344:
5341:
5339:
5336:
5334:
5331:
5329:
5326:
5324:
5321:
5319:
5316:
5314:
5311:
5310:
5308:
5304:
5298:
5295:
5293:
5289:
5286:
5284:
5281:
5279:
5276:
5274:
5271:
5269:
5266:
5264:
5261:
5259:
5256:
5254:
5251:
5249:
5246:
5244:
5241:
5237:
5234:
5232:
5229:
5228:
5227:
5224:
5222:
5219:
5217:
5214:
5212:
5209:
5207:
5204:
5202:
5199:
5197:
5194:
5192:
5189:
5187:
5184:
5182:
5179:
5177:
5174:
5172:
5169:
5167:
5164:
5162:
5159:
5156:
5153:
5151:
5147:
5144:
5142:
5139:
5135:
5132:
5130:
5127:
5126:
5125:
5122:
5120:
5117:
5113:
5110:
5108:
5105:
5104:
5103:
5100:
5098:
5095:
5093:
5090:
5088:
5085:
5083:
5080:
5078:
5075:
5073:
5070:
5068:
5065:
5063:
5060:
5059:
5057:
5053:
5047:
5044:
5042:
5039:
5037:
5034:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5014:
5012:
5009:
5007:
5004:
5002:
4999:
4997:
4994:
4992:
4989:
4987:
4984:
4982:
4979:
4977:
4974:
4972:
4969:
4967:
4964:
4960:
4957:
4955:
4952:
4951:
4950:
4947:
4945:
4942:
4940:
4937:
4935:
4932:
4928:
4925:
4923:
4920:
4918:
4915:
4914:
4913:
4910:
4908:
4905:
4903:
4900:
4898:
4895:
4893:
4890:
4886:
4883:
4881:
4878:
4877:
4876:
4873:
4871:
4868:
4866:
4863:
4861:
4858:
4856:
4853:
4851:
4848:
4846:
4843:
4839:
4836:
4834:
4831:
4830:
4829:
4826:
4823:
4820:
4818:
4815:
4813:
4810:
4808:
4805:
4803:
4799:
4796:
4794:
4791:
4787:
4784:
4782:
4779:
4777:
4774:
4773:
4772:
4769:
4767:
4764:
4762:
4759:
4757:
4754:
4752:
4749:
4747:
4744:
4743:
4741:
4737:
4731:
4728:
4726:
4723:
4721:
4718:
4716:
4713:
4711:
4708:
4706:
4703:
4701:
4698:
4696:
4693:
4691:
4688:
4686:
4683:
4681:
4678:
4676:
4673:
4671:
4668:
4666:
4663:
4661:
4658:
4656:
4653:
4651:
4648:
4646:
4643:
4641:
4638:
4636:
4633:
4631:
4628:
4626:
4623:
4621:
4618:
4616:
4613:
4611:
4608:
4604:
4601:
4599:
4596:
4595:
4594:
4591:
4587:
4584:
4582:
4579:
4578:
4577:
4574:
4572:
4569:
4567:
4564:
4562:
4559:
4557:
4554:
4552:
4549:
4547:
4544:
4542:
4539:
4537:
4534:
4532:
4529:
4527:
4524:
4522:
4519:
4517:
4514:
4510:
4507:
4505:
4502:
4501:
4500:
4497:
4495:
4492:
4490:
4487:
4485:
4482:
4480:
4477:
4475:
4472:
4470:
4467:
4466:
4464:
4460:
4454:
4451:
4449:
4446:
4444:
4441:
4439:
4436:
4434:
4431:
4429:
4426:
4424:
4421:
4419:
4416:
4414:
4410:
4407:
4405:
4402:
4400:
4397:
4395:
4392:
4390:
4387:
4385:
4382:
4378:
4375:
4373:
4370:
4368:
4365:
4363:
4360:
4358:
4355:
4353:
4350:
4349:
4348:
4345:
4343:
4340:
4338:
4335:
4333:
4330:
4328:
4325:
4323:
4320:
4316:
4313:
4311:
4308:
4307:
4306:
4303:
4301:
4298:
4296:
4293:
4291:
4288:
4286:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4263:
4259:
4256:
4254:
4251:
4249:
4246:
4244:
4241:
4239:
4236:
4234:
4231:
4230:
4229:
4226:
4222:
4219:
4217:
4214:
4212:
4209:
4208:
4207:
4204:
4202:
4199:
4195:
4192:
4190:
4187:
4185:
4182:
4181:
4180:
4177:
4175:
4172:
4170:
4167:
4165:
4162:
4160:
4157:
4155:
4152:
4150:
4147:
4145:
4142:
4140:
4137:
4135:
4132:
4130:
4127:
4126:
4124:
4120:
4114:
4111:
4107:
4104:
4102:
4099:
4097:
4094:
4092:
4089:
4087:
4084:
4082:
4079:
4078:
4077:
4074:
4072:
4069:
4067:
4064:
4062:
4059:
4057:
4054:
4052:
4049:
4047:
4044:
4040:
4037:
4035:
4032:
4030:
4027:
4025:
4022:
4021:
4020:
4017:
4015:
4012:
4010:
4007:
4005:
4002:
4000:
3997:
3995:
3992:
3990:
3987:
3985:
3982:
3980:
3977:
3975:
3972:
3968:
3965:
3963:
3960:
3959:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3881:
3878:
3876:
3873:
3872:
3871:
3868:
3866:
3863:
3861:
3858:
3856:
3853:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3831:
3830:
3829:
3826:
3824:
3821:
3819:
3816:
3812:
3809:
3808:
3807:
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3780:
3777:
3775:
3772:
3770:
3767:
3766:
3765:
3762:
3760:
3757:
3753:
3750:
3748:
3745:
3743:
3740:
3738:
3735:
3733:
3730:
3729:
3728:
3725:
3724:
3722:
3718:
3713:
3709:
3705:
3698:
3693:
3691:
3686:
3684:
3679:
3678:
3675:
3661:
3655:
3650:
3646:
3637:
3632:
3630:
3625:
3623:
3618:
3617:
3614:
3607:
3603:
3600:
3599:
3595:
3588:
3584:
3580:
3576:
3572:
3568:
3564:
3560:
3555:
3551:
3547:
3543:
3539:
3535:
3531:
3528:(1): 113β24.
3527:
3523:
3518:
3514:
3510:
3505:
3500:
3495:
3490:
3486:
3482:
3479:(10): e3312.
3478:
3474:
3470:
3465:
3461:
3457:
3452:
3447:
3442:
3437:
3433:
3429:
3425:
3421:
3417:
3412:
3408:
3404:
3400:
3396:
3393:(3): 259β71.
3392:
3388:
3387:
3381:
3377:
3373:
3369:
3365:
3362:(4): 257β66.
3361:
3357:
3352:
3348:
3344:
3340:
3336:
3332:
3328:
3324:
3320:
3315:
3311:
3307:
3303:
3297:
3293:
3289:
3285:
3280:
3279:
3274:
3265:
3260:
3256:
3252:
3247:
3242:
3238:
3234:
3230:
3223:
3220:
3215:
3211:
3207:
3203:
3199:
3195:
3188:
3185:
3180:
3174:
3170:
3163:
3160:
3154:
3150:
3147:Nat Pernick.
3143:
3141:
3139:
3137:
3135:
3133:
3131:
3127:
3122:
3118:
3113:
3108:
3104:
3100:
3096:
3092:
3088:
3081:
3078:
3073:
3069:
3064:
3059:
3055:
3051:
3047:
3040:
3037:
3032:
3028:
3023:
3018:
3014:
3010:
3006:
2999:
2996:
2991:
2987:
2982:
2977:
2973:
2969:
2965:
2961:
2957:
2950:
2947:
2942:
2938:
2933:
2928:
2924:
2920:
2919:J. Biol. Chem
2916:
2909:
2906:
2901:
2897:
2892:
2887:
2883:
2879:
2878:J. Biol. Chem
2875:
2868:
2865:
2860:
2856:
2851:
2846:
2843:(9): 6061β4.
2842:
2838:
2837:J. Biol. Chem
2834:
2827:
2824:
2819:
2815:
2810:
2805:
2802:(2): 187β93.
2801:
2797:
2793:
2786:
2783:
2778:
2774:
2769:
2764:
2760:
2756:
2755:J. Biol. Chem
2752:
2745:
2742:
2737:
2733:
2728:
2723:
2719:
2715:
2711:
2704:
2701:
2696:
2692:
2687:
2682:
2678:
2674:
2670:
2663:
2660:
2655:
2651:
2646:
2641:
2637:
2633:
2629:
2622:
2619:
2614:
2610:
2606:
2602:
2595:
2593:
2589:
2584:
2580:
2575:
2570:
2566:
2562:
2561:J. Biol. Chem
2558:
2551:
2549:
2545:
2540:
2536:
2532:
2528:
2521:
2519:
2515:
2510:
2506:
2502:
2498:
2494:
2490:
2483:
2480:
2475:
2471:
2466:
2461:
2457:
2453:
2449:
2445:
2441:
2434:
2431:
2426:
2422:
2418:
2414:
2411:(2): 211β22.
2410:
2406:
2398:
2395:
2390:
2386:
2381:
2376:
2371:
2366:
2362:
2358:
2354:
2347:
2344:
2339:
2335:
2331:
2327:
2323:
2319:
2312:
2310:
2306:
2301:
2297:
2293:
2289:
2285:
2281:
2274:
2271:
2266:
2262:
2257:
2252:
2249:(9): 6171β7.
2248:
2244:
2240:
2233:
2230:
2225:
2219:
2216:
2211:
2207:
2203:
2199:
2195:
2191:
2184:
2181:
2176:
2172:
2167:
2162:
2157:
2152:
2148:
2144:
2140:
2133:
2131:
2127:
2122:
2118:
2114:
2110:
2106:
2102:
2098:
2094:
2087:
2084:
2079:
2075:
2071:
2067:
2063:
2059:
2052:
2049:
2044:
2040:
2036:
2032:
2027:
2022:
2018:
2014:
2010:
2003:
2001:
1997:
1992:
1988:
1983:
1978:
1974:
1970:
1966:
1959:
1956:
1951:
1947:
1941:
1938:
1934:
1930:
1925:
1923:
1921:
1917:
1911:
1907:
1904:
1902:
1899:
1897:
1894:
1893:
1889:
1887:
1885:
1880:
1877:
1873:
1872:immune system
1869:
1861:
1854:
1849:
1846:
1844:
1841:
1840:
1835:
1832:
1830:
1826:
1824:
1820:
1819:
1818:
1817:
1813:
1809:
1808:
1802:
1798:
1795:
1792:
1789:
1787:
1783:
1782:Type II cells
1780:
1777:
1774:
1772:
1768:
1767:
1766:
1765:
1761:
1760:
1757:
1754:
1753:
1750:
1747:
1745:
1744:Paraganglioma
1742:
1740:
1739:Neuroblastoma
1737:
1735:
1732:
1730:
1727:
1724:
1721:
1719:
1716:
1715:
1711:
1707:
1704:
1702:
1699:
1698:
1695:
1692:
1690:
1687:
1686:
1683:
1680:
1679:
1678:
1673:
1670:
1667:
1664:
1662:
1659:
1657:
1656:Plasmacytomas
1654:
1652:
1649:
1647:
1644:
1642:
1639:
1637:(epithelioid)
1636:
1635:Mesotheliomas
1633:
1631:
1628:
1627:
1622:
1619:
1617:
1614:
1611:
1608:
1606:
1603:
1602:
1601:
1600:
1596:
1593:
1589:
1585:
1581:
1578:
1574:
1571:
1569:
1566:
1564:
1561:
1559:
1556:
1554:
1550:
1547:
1546:
1541:
1538:
1536:
1533:
1531:
1530:Breast cancer
1528:
1527:
1526:
1525:
1522:
1519:
1518:
1515:
1512:
1511:
1510:
1509:
1502:
1498:
1494:
1490:
1486:
1482:
1478:
1475:
1471:
1468:
1465:
1464:
1463:
1461:
1457:
1453:
1445:
1443:
1440:
1437:
1429:
1424:
1422:
1420:
1416:
1412:
1408:
1404:
1400:
1399:interleukin 7
1396:
1392:
1388:
1380:
1378:
1376:
1372:
1368:
1364:
1360:
1356:
1352:
1348:
1344:
1340:
1335:
1332:
1328:
1320:
1318:
1311:
1306:
1303:
1300:
1297:
1294:
1291:
1288:
1285:
1282:
1279:
1278:
1277:
1275:
1267:
1265:
1263:
1260:
1256:
1252:
1251:glycosylation
1247:
1241:
1239:
1237:
1233:
1228:
1223:
1220:
1218:
1214:
1210:
1205:
1203:
1200:
1192:
1190:
1188:
1184:
1180:
1176:
1172:
1168:
1165:
1161:
1157:
1153:
1149:
1145:
1141:
1127:
1123:
1119:
1116:
1112:
1102:
1100:
1097:
1093:
1087:
1084:
1080:
1076:
1069:
1063:
1059:
1056:
1050:
1048:
1044:
1040:
1036:
1032:
1028:
1024:
1020:
1016:
1012:
1008:
1004:
1000:
996:
992:
988:
984:
980:
976:
970:
966:
962:
958:
954:
950:
946:
943:
939:
932:
926:
922:
919:
913:
911:
907:
903:
899:
895:
891:
887:
883:
879:
875:
871:
867:
863:
859:
855:
851:
847:
843:
837:
833:
829:
825:
821:
817:
813:
810:
808:RefSeq (mRNA)
806:
799:
795:
791:
788:
782:
781:
777:
772:
768:
765:
763:
759:
752:
748:
744:
741:
735:
734:
729:
725:
722:
720:
716:
709:
705:
701:
698:
692:
691:
686:
682:
679:
677:
673:
670:
667:
665:
662:
658:
655:
651:
647:
640:
636:
631:
625:
622:
620:
617:
615:
612:
610:
607:
605:
602:
600:
597:
595:
592:
590:
587:
585:
582:
580:
577:
575:
572:
571:
569:
566:
565:
559:
556:
554:
551:
549:
546:
544:
541:
539:
536:
534:
531:
529:
526:
524:
521:
519:
516:
514:
511:
509:
506:
504:
501:
500:
498:
495:
494:
488:
485:
483:
480:
478:
475:
473:
470:
469:
467:
464:
463:
460:
459:Gene ontology
456:
452:
440:
435:
431:
424:
417:
412:
409:
407:
403:
395:
390:
380:
377:
373:
370:
360:
356:
352:
348:
344:
340:
336:
332:
328:
324:
323:
320:
316:
311:
308:
307:
304:
302:
298:
296:
295:
291:
290:
287:
285:
281:
277:
273:
269:
261:
256:
252:
248:
243:
233:
229:
222:
215:
209:
202:
198:
192:
188:
184:
179:
175:
170:
166:
162:
158:
154:
150:
146:
142:
138:
134:
126:
121:
114:
109:
104:
93:
91:
87:
81:
76:
73:
72:
68:
65:
58:
54:
49:
45:
41:
36:
31:
27:Human protein
19:
6267:
6266:
6144:4-1BB ligand
6056:Fibromodulin
5761:Mucoproteins
5225:
5145:
5123:
5101:
4948:
4911:
4874:
4827:
4797:
4770:
4592:
4498:
4346:
4075:
3827:
3659:
3562:
3558:
3525:
3521:
3476:
3472:
3426:(4): e2054.
3423:
3419:
3390:
3384:
3359:
3355:
3322:
3318:
3283:
3236:
3232:
3222:
3197:
3194:Chem Soc Rev
3193:
3187:
3168:
3162:
3152:
3094:
3090:
3080:
3053:
3049:
3039:
3012:
3008:
2998:
2963:
2959:
2949:
2922:
2918:
2908:
2881:
2877:
2867:
2840:
2836:
2826:
2799:
2795:
2785:
2758:
2754:
2744:
2720:(1): 20β31.
2717:
2713:
2703:
2676:
2672:
2662:
2635:
2631:
2621:
2604:
2600:
2564:
2560:
2530:
2526:
2495:(2): 440β3.
2492:
2488:
2482:
2447:
2443:
2433:
2408:
2404:
2397:
2360:
2356:
2346:
2321:
2317:
2283:
2279:
2273:
2246:
2242:
2232:
2218:
2193:
2189:
2183:
2146:
2142:
2096:
2092:
2086:
2061:
2057:
2051:
2019:(1): 45β60.
2016:
2012:
1972:
1968:
1958:
1949:
1940:
1881:
1874:by training
1865:
1852:
1651:Perineurioma
1584:Type II cell
1489:mesothelioma
1481:cytokeratins
1449:
1441:
1433:
1391:Beta-catenin
1384:
1363:cytochrome c
1336:
1324:
1315:
1271:
1268:Interactions
1248:
1245:
1224:
1221:
1206:
1199:glycosylated
1196:
1171:glycoprotein
1163:
1155:
1151:
1147:
1143:
1139:
1138:
1065:
1035:NP_001358649
1027:NP_001191226
1023:NP_001191225
1019:NP_001191224
1015:NP_001191223
1011:NP_001191222
1007:NP_001191221
1003:NP_001191220
999:NP_001191219
995:NP_001191218
991:NP_001191217
987:NP_001191216
983:NP_001191215
979:NP_001191214
975:NP_001037858
972:
965:NP_001037857
961:NP_001037856
957:NP_001037855
953:NP_001018017
949:NP_001018016
928:
910:NM_001371720
898:NM_001204297
894:NM_001204296
890:NM_001204295
886:NM_001204294
882:NM_001204293
878:NM_001204292
874:NM_001204291
870:NM_001204290
866:NM_001204289
862:NM_001204288
858:NM_001204287
854:NM_001204286
850:NM_001204285
846:NM_001044393
842:NM_001044392
839:
832:NM_001044391
828:NM_001044390
824:NM_001018021
820:NM_001018017
816:NM_001018016
797:
774:
750:
731:
707:
688:
668:
663:
299:
292:
258:155,192,916
245:155,185,824
128:External IDs
83:
6256:Vitronectin
6251:Uteroglobin
6241:Transcortin
6214:Glycophorin
6184:Osteonectin
6169:Lactoferrin
5894:Orosomucoid
5884:Haptoglobin
3642:PDB gallery
3565:(1): 21β6.
2673:J Biol Chem
2632:Cancer Cell
2357:PLOS Pathog
1803:of the skin
1771:Toker cells
1729:Liposarcoma
1588:hyperplasia
1339:fibroblasts
1257:. e.g. The
1181:binding to
523:Golgi lumen
487:p53 binding
106:Identifiers
6284:Categories
6084:Syndecan 1
3710:(see also
3009:Cancer Res
2601:Cancer Res
2196:: 431β57.
1935:, May 2017
1912:References
1821:Activated
1630:Meningioma
1485:metastatic
1460:neoplastic
1458:and their
1375:Neuregulin
1371:Src (gene)
1255:carcinomas
303:(ortholog)
141:HomoloGene
6194:Protein S
6189:Protein C
6164:Hemopexin
6154:Clusterin
6066:Keratocan
3255:2051-1426
1834:Monocytes
1778:of kidney
1725:(usually)
1597:Lymphomas
1592:dysplasia
1586:lesions (
1501:cytoplasm
1493:micovilli
1456:epithelia
1213:sheddases
1209:epithelia
1193:Structure
1031:NP_002447
906:NM_182741
902:NM_002456
654:Orthologs
508:cytoplasm
149:GeneCards
6013:Brevican
6008:Neurocan
6003:Aggrecan
5981:Perlecan
5976:Testican
5954:Versican
5949:Biglycan
5909:Ovomucin
3704:Proteins
3587:37471701
3579:25614211
3550:25176184
3542:19415485
3513:18833326
3473:PLOS ONE
3460:18446242
3420:PLOS ONE
3407:17504123
3376:17128152
3347:36159399
3339:16925492
3310:11787681
3214:23440054
3121:21102519
3091:Oncogene
3072:12618757
3050:Oncogene
3031:16288032
2941:11877440
2900:11483589
2859:11152665
2818:12750561
2736:16158055
2714:Oncogene
2695:14999001
2654:15710329
2583:11278868
2539:12939402
2509:11181067
2474:28884042
2425:12525512
2389:19816567
2338:16904320
2300:12054500
2210:17850209
2175:14711375
2121:32520673
2113:11547902
2078:12855381
2043:23171728
2035:14681689
1931:–
1890:See also
1810:Several
1790:Pancreas
1734:Melanoma
1708:(except
1553:chordoma
1436:epitopes
1411:vimentin
1387:interact
1274:interact
1242:Function
1179:pathogen
1158:), is a
1115:Wikidata
633:Sources:
538:membrane
6061:Lumican
5944:Decorin
5741:Protein
5512:301β350
5306:251β300
5258:CD240CE
5055:201β250
4739:151β200
4462:101β150
3504:2553196
3481:Bibcode
3451:2329594
3428:Bibcode
3264:3990302
3112:3063863
2990:9819408
2777:9139698
2613:7664271
2465:5570602
2380:2752161
2265:1556125
1991:1697589
1933:Ensembl
1906:Mucin-1
1884:vaccine
1876:T-cells
1829:B cells
1823:T cells
1797:eccrine
1674:(often)
1641:Myeloma
1495:, from
762:UniProt
719:Ensembl
660:Species
639:QuickGO
543:vesicle
518:nucleus
325:pylorus
278:pattern
113:Aliases
6300:Mucins
6134:Avidin
5813:MUC5AC
5519:CD300A
5478:CDw293
5263:CD240D
5124:CD213a
5102:CDw210
5067:CD202b
5041:CDw199
5036:CDw198
4690:CD140b
4122:51β100
3608:(MeSH)
3585:
3577:
3548:
3540:
3511:
3501:
3458:
3448:
3405:
3374:
3345:
3337:
3308:
3298:
3261:
3253:
3212:
3175:
3119:
3109:
3070:
3029:
2988:
2981:109303
2978:
2939:
2898:
2857:
2816:
2775:
2734:
2693:
2652:
2611:
2581:
2537:
2507:
2472:
2462:
2423:
2387:
2377:
2336:
2298:
2263:
2208:
2173:
2166:320498
2163:
2119:
2111:
2076:
2041:
2033:
1989:
1853:
1582:Lung:
1450:Using
1355:Bcl-xL
1281:CTNND1
1276:with:
1098:search
1096:PubMed
780:Q7Z551
776:P15941
676:Entrez
406:BioGPS
341:cardia
145:136477
137:158340
6097:Other
6028:CSPG5
6023:CSPG4
5877:Other
5868:MUC20
5863:MUC19
5858:MUC17
5853:MUC16
5848:MUC15
5843:MUC13
5838:MUC12
5818:MUC5B
5803:MUC3B
5798:MUC3A
5783:CD164
5770:Mucin
5699:CD350
5694:CD349
5689:CD344
5684:CD340
5679:CD339
5674:CD338
5669:CD337
5664:CD336
5659:CD335
5654:CD334
5649:CD333
5644:CD332
5639:CD331
5634:CD329
5629:CD328
5624:CD327
5619:CD326
5614:CD325
5609:CD324
5604:CD322
5599:CD321
5594:CD320
5589:CD318
5584:CD317
5579:CD316
5574:CD315
5569:CD314
5564:CD312
5559:CD309
5554:CD307
5549:CD306
5544:CD305
5539:CD304
5534:CD303
5529:CD302
5524:CD301
5503:CD299
5498:CD298
5493:CD297
5488:CD295
5483:CD294
5473:CD292
5468:CD290
5463:CD289
5458:CD288
5453:CD286
5448:CD284
5443:CD283
5438:CD282
5433:CD281
5428:CD280
5423:CD279
5418:CD278
5413:CD276
5408:CD275
5403:CD274
5398:CD273
5393:CD272
5388:CD271
5383:CD269
5378:CD268
5373:CD267
5368:CD266
5363:CD265
5358:CD264
5353:CD263
5348:CD262
5343:CD261
5338:CD258
5333:CD257
5328:CD256
5323:CD254
5318:CD253
5313:CD252
5297:CD249
5292:CD248
5288:CD247
5283:CD246
5278:CD244
5273:CD243
5268:CD241
5253:CD239
5248:CD238
5243:CD236
5226:CD235
5221:CD234
5216:CD233
5211:CD230
5206:CD229
5201:CD228
5196:CD227
5191:CD226
5186:CD225
5181:CD224
5176:CD223
5171:CD222
5166:CD221
5161:CD220
5146:CD218
5141:CD217
5119:CD212
5097:CD209
5092:CD208
5087:CD207
5082:CD206
5077:CD205
5072:CD204
5062:CD201
5046:CD200
5031:CD197
5026:CD196
5021:CD195
5016:CD194
5011:CD193
5006:CD192
5001:CD191
4996:CD186
4991:CD185
4986:CD184
4981:CD183
4976:CD182
4971:CD181
4966:CD180
4949:CD179
4944:CD178
4939:CD177
4934:CD174
4912:CD172
4907:CD171
4902:CD170
4897:CD169
4892:CD168
4875:CD167
4870:CD166
4865:CD164
4860:CD163
4855:CD162
4850:CD161
4845:CD160
4828:CD159
4798:CD158
4793:CD157
4771:CD156
4766:CD155
4761:CD154
4756:CD153
4751:CD152
4746:CD151
4730:CD150
4725:CD148
4720:CD147
4715:CD146
4710:CD144
4705:CD143
4700:CD142
4695:CD141
4685:CD138
4680:CD137
4675:CD136
4670:CD135
4665:CD134
4660:CD133
4655:CD132
4650:CD131
4645:CD130
4640:CD129
4635:CD127
4630:CD126
4625:CD125
4620:CD124
4615:CD123
4610:CD122
4593:CD121
4576:CD120
4571:CD119
4566:CD118
4561:CD117
4556:CD116
4551:CD115
4546:CD114
4541:CD113
4536:CD112
4531:CD111
4526:CD110
4521:CD109
4516:CD108
4499:CD107
4494:CD106
4489:CD105
4484:CD104
4479:CD103
4474:CD102
4469:CD101
4453:CD100
3583:S2CID
3546:S2CID
3343:S2CID
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2117:S2CID
2039:S2CID
1827:Some
1407:GSK3B
1403:PRKCD
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1367:hsp90
1351:Bcl-2
1301:, and
1287:ERBB2
1259:CanAg
1160:mucin
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669:Mouse
664:Human
635:Amigo
301:Mouse
294:Human
241:Start
174:Human
6209:CD43
6124:CD70
6109:ADAM
6018:CD44
5833:MUC8
5828:MUC7
5823:MUC6
5808:MUC4
5793:MUC2
5788:MUC1
5778:CD43
5751:and
4448:CD99
4443:CD98
4438:CD97
4433:CD96
4428:CD95
4423:CD94
4418:CD93
4413:CD92
4409:CD91
4404:CD90
4399:CD89
4394:CD88
4389:CD87
4384:CD86
4347:CD85
4342:CD84
4337:CD83
4332:CD82
4327:CD81
4322:CD80
4305:CD79
4300:CD78
4295:CD74
4290:CD73
4285:CD72
4280:CD71
4275:CD70
4270:CD69
4265:CD68
4228:CD66
4206:CD64
4201:CD63
4179:CD62
4174:CD61
4169:CD59
4164:CD58
4159:CD57
4154:CD56
4149:CD55
4144:CD54
4139:CD53
4134:CD52
4129:CD51
4113:CD50
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4071:CD48
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4061:CD46
4056:CD45
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4019:CD42
4014:CD41
4009:CD40
4004:CD39
3999:CD38
3994:CD37
3989:CD36
3984:CD35
3979:CD34
3974:CD33
3957:CD32
3952:CD31
3947:CD30
3942:CD29
3937:CD28
3932:CD27
3927:CD26
3922:CD25
3917:CD24
3912:CD23
3907:CD22
3902:CD21
3897:CD20
3892:CD19
3887:CD18
3870:CD16
3865:CD15
3860:CD14
3855:CD13
3828:CD11
3823:CD10
3720:1β50
3660:2acm
3575:PMID
3538:PMID
3509:PMID
3456:PMID
3403:PMID
3372:PMID
3335:PMID
3306:PMID
3296:ISBN
3251:ISSN
3210:PMID
3173:ISBN
3117:PMID
3068:PMID
3027:PMID
2986:PMID
2937:PMID
2896:PMID
2855:PMID
2814:PMID
2773:PMID
2732:PMID
2691:PMID
2650:PMID
2609:PMID
2579:PMID
2535:PMID
2505:PMID
2470:PMID
2421:PMID
2385:PMID
2334:PMID
2296:PMID
2261:PMID
2206:PMID
2171:PMID
2109:PMID
2074:PMID
2031:PMID
1987:PMID
1799:and
1415:CDH2
1413:and
1359:PI3K
1353:and
1305:SOS1
1293:GRB2
1232:urea
1217:VNTR
1167:gene
1164:MUC1
690:4582
284:Bgee
237:1q22
232:Band
191:Chr.
153:MUC1
133:OMIM
120:MUC1
90:2ACM
86:1SM3
67:RCSB
64:PDBe
33:MUC1
3818:CD9
3806:CD8
3801:CD7
3796:CD6
3791:CD5
3786:CD4
3764:CD3
3759:CD2
3732:a-c
3727:CD1
3567:doi
3530:doi
3526:118
3499:PMC
3489:doi
3446:PMC
3436:doi
3395:doi
3364:doi
3327:doi
3288:doi
3259:PMC
3241:doi
3202:doi
3107:PMC
3099:doi
3058:doi
3017:doi
2976:PMC
2968:doi
2927:doi
2923:277
2886:doi
2882:276
2845:doi
2841:276
2804:doi
2763:doi
2759:272
2722:doi
2681:doi
2677:279
2640:doi
2569:doi
2565:276
2497:doi
2493:281
2460:PMC
2452:doi
2413:doi
2375:PMC
2365:doi
2326:doi
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2284:293
2251:doi
2247:267
2198:doi
2161:PMC
2151:doi
2101:doi
2066:doi
2021:doi
1977:doi
1973:265
1784:of
1395:LYN
1343:Akt
1331:p21
1327:p53
1299:JUP
1156:EMA
1148:PEM
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1089:n/a
1067:n/a
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