1007:
116:
141:
147:
3158:
1202:
FANCD2 mutant mice have a significantly increased incidence of tumors including ovarian, gastric and hepatic adenomas as well as hepatocellular, lung, ovarian and mammary carcinomas. Humans with a FANCD2 deficiency have increased acute myeloid leukemia, and squamous cell carcinomas (head and neck
1068:
repair of DNA during double strand break repair. In this process, an ATP dependent DNA strand exchange takes place in which a single strand invades base-paired strands of homologous DNA molecules. RAD51 is involved in the search for homology and strand pairing stages of the
3751:
Reuter TY, Medhurst AL, Waisfisz Q, Zhi Y, Herterich S, Hoehn H, et al. (October 2003). "Yeast two-hybrid screens imply involvement of
Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport".
2366:
Reuter TY, Medhurst AL, Waisfisz Q, Zhi Y, Herterich S, Hoehn H, et al. (October 2003). "Yeast two-hybrid screens imply involvement of
Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport".
1088:. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is
3290:"The Chinese hamster FANCG/XRCC9 mutant NM3 fails to express the monoubiquitinated form of the FANCD2 protein, is hypersensitive to a range of DNA damaging agents and exhibits a normal level of spontaneous sister chromatid exchange"
1162:
Humans with a FANCD deficiency display hypogonadism, male infertility, impaired spermatogenesis, and reduced female fertility. Similarly, mice deficient in FANCD2 show hypogonadism, impaired fertility and impaired gametogenesis.
1186:
loss. Activated FANCD2 protein may normally function prior to the initiation of meiotic recombination, perhaps to prepare chromosomes for synapsis, or to regulate subsequent recombination events.
1340:
Whitney M, Thayer M, Reifsteck C, Olson S, Smith L, Jakobs PM, et al. (November 1995). "Microcell mediated chromosome transfer maps the
Fanconi anaemia group D gene to chromosome 3p".
2128:
Prieto-Garcia, C.; Hartmann, O; Diefenbacher, M.; et, al. (Sep 2020). "Inhibition of USP28 overcomes
Cisplatin-Resistance of Squamous Tumors by Suppression of the Fanconi Anemia Pathway".
1044:. The PALB2 protein acts as a hub, bringing together BRCA1, BRCA2 and RAD51 at the site of a DNA double-strand break, and also binds to RAD51C, a member of the RAD51 paralog complex
154:
1154:
recruitment and its consequent activity restrain DNA replication fork progression and prevent chromosome abnormalities from occurring when DNA replication forks stall.
3714:
Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, et al. (October 2003). "A novel ubiquitin ligase is deficient in
Fanconi anemia".
3502:
Nakanishi K, Taniguchi T, Ranganathan V, New HV, Moreau LA, Stotsky M, et al. (December 2002). "Interaction of FANCD2 and NBS1 in the DNA damage response".
1555:
Castillo P, Bogliolo M, Surralles J (May 2011). "Coordinated action of the
Fanconi anemia and ataxia telangiectasia pathways in response to oxidative damage".
3539:
Goldberg M, Stucki M, Falck J, D'Amours D, Rahman D, Pappin D, et al. (February 2003). "MDC1 is required for the intra-S-phase DNA damage checkpoint".
3658:
Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X (July 2003). "Menin associates with FANCD2, a protein involved in repair of DNA damage".
2677:
Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X (July 2003). "Menin associates with FANCD2, a protein involved in repair of DNA damage".
1143:. The monoubiquitinated FANCD2:FANCI complex coats DNA in a filament-like array, potentially as a way to protect DNA associated with stalled replication.
593:
77:
574:
1139:
Mono-ubiquination of FANCD2 is essential for repairing DNA interstrand crosslinks, and clamps the protein on DNA together with its partner protein
3091:
1203:
squamous cell carcinomas and anogenital carcinomas). Lung squamous tumors express high levels of FANCD2 and members of
Fanconia anemia pathway.
3065:
1322:
1304:
3834:
2726:
1006:
3629:
Gordon SM, Buchwald M (July 2003). "Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems".
2781:
2593:
Gordon SM, Buchwald M (July 2003). "Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems".
3034:
2965:
1182:(breast cancer susceptibility protein). FANCD2 mutant mice exhibit chromosome mis-pairing during the pachytene stage of meiosis and
839:
3584:
Stewart GS, Wang B, Bignell CR, Taylor AM, Elledge SJ (February 2003). "MDC1 is a mediator of the mammalian DNA damage checkpoint".
3049:
1291:
1077:
1723:"Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway"
140:
115:
1227:
1013:
1287:
3024:
2931:
57:
3481:
Tamary H, Bar-Yam R, Zemach M, Dgany O, Shalmon L, Yaniv I (October 2002). "The molecular biology of
Fanconi anemia".
1215:
153:
2151:"Methodology for the identification of small molecule inhibitors of the Fanconi Anaemia ubiquitin E3 ligase complex"
2953:
2777:
2770:
146:
1194:
Tobacco smoke suppresses the expression of FANCD2, which codes for a DNA damage "caretaker" or repair mechanism.
1100:) involved in homology-directed DNA repair (see Figure: Recombinational repair of DNA double-strand damages). A
2948:
2870:
2719:
1065:
65:
3259:
Futaki M, Liu JM (December 2001). "Chromosomal breakage syndromes and the BRCA1 genome surveillance complex".
1980:"Uncoupling of transcription and translation of Fanconi anemia (FANC) complex proteins during spermatogenesis"
1818:"Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays"
1170:, pre-leptotene spermatocytes, and in spermatocytes in the leptotene, zygotene and early pachytene stages of
3839:
619:
3060:
2970:
2765:
48:, FA-D2, FA4, FACD, FAD, FAD2, FANCD, Fanconi anemia complementation group D2, FA complementation group D2
3183:"Localization of the Fanconi anemia complementation group D gene to a 200-kb region on chromosome 3p25.3"
2081:"Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression"
2826:
3593:
3548:
2751:
2270:
2162:
2129:
1880:
1175:
129:
3224:
Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, et al. (February 2001).
1775:
Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, et al. (February 2001).
44:
3161:
2848:
2712:
1060:(BCDX2). The BCDX2 complex is responsible for RAD51 recruitment or stabilization at damage sites.
822:
818:
797:
787:
783:
775:
771:
751:
747:
726:
716:
712:
708:
700:
3739:
3617:
3572:
3527:
3391:
3348:
2345:
2079:
Hays LE, Zodrow DM, Yates JE, Deffebach ME, Jacoby DB, Olson SB, Pankow JF, Bagby GC (May 2008).
1425:
1365:
89:
3446:
Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD (October 2002).
3360:
Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, et al. (May 2002).
2314:
Taniguchi T, Garcia-Higuera I, Xu B, Andreassen PR, Gregory RC, Kim ST, et al. (May 2002).
1631:
Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD (October 2002).
779:
704:
3288:
Wilson JB, Johnson MA, Stuckert AP, Trueman KL, May S, Bryant PE, et al. (December 2001).
1869:"Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability"
1592:"Tumor suppressor CHK2: regulator of DNA damage response and mediator of chromosomal stability"
3812:
3769:
3731:
3702:
3667:
3646:
3609:
3564:
3519:
3490:
3469:
3434:
3383:
3340:
3311:
3276:
3247:
3212:
3044:
2686:
2659:
2610:
2575:
2542:
Hejna J, Holtorf M, Hines J, Mathewson L, Hemphill A, Al-Dhalimy M, et al. (April 2008).
2521:
2477:
2428:
2384:
2337:
2296:
2239:
2188:
2110:
2061:
2009:
1960:
1906:
1849:
1798:
1752:
1703:
1654:
1613:
1572:
1537:
1486:
1406:
1357:
1092:
in response to DNA damage, resulting in its localization to nuclear foci with other proteins (
37:
1816:
Tan W, van Twest S, Leis A, Bythell-Douglas R, Murphy VJ, Sharp M, et al. (March 2020).
1383:
Timmers C, Taniguchi T, Hejna J, Reifsteck C, Lucas L, Bruun D, et al. (February 2001).
1206:
FANCD2 monoubiquitination is also a potential therapeutic target in the treatment of cancer.
3802:
3794:
3761:
3723:
3692:
3638:
3601:
3556:
3511:
3459:
3424:
3416:
3373:
3332:
3301:
3268:
3237:
3202:
3194:
2649:
2641:
2602:
2565:
2555:
2511:
2467:
2459:
2418:
2376:
2327:
2286:
2278:
2259:"Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway"
2229:
2219:
2178:
2170:
2100:
2092:
2051:
2043:
1999:
1991:
1950:
1942:
1896:
1888:
1839:
1829:
1788:
1742:
1734:
1693:
1685:
1644:
1603:
1564:
1527:
1517:
1476:
1468:
1437:
1396:
1349:
233:
164:
85:
998:. Fanconi anemia proteins, including FANCD2, are an emerging therapeutic target in cancer
995:
983:
3448:"S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51"
3181:
Hejna JA, Timmers CD, Reifsteck C, Bruun DA, Lucas LW, Jakobs PM, et al. (May 2000).
2760:
2030:
Houghtaling S, Timmers C, Noll M, Finegold MJ, Jones SN, Meyn MS, Grompe M (August 2003).
1633:"S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51"
208:
2257:
Joo W, Xu G, Persky NS, Smogorzewska A, Rudge DG, Buzovetsky O, et al. (July 2011).
3783:"Chk1-mediated phosphorylation of FANCE is required for the Fanconi anemia/BRCA pathway"
3597:
3552:
2274:
2166:
1884:
3807:
3782:
3207:
3182:
2570:
2544:"Tip60 is required for DNA interstrand cross-link repair in the Fanconi anemia pathway"
2543:
2498:
Hussain S, Wilson JB, Medhurst AL, Hejna J, Witt E, Ananth S, et al. (June 2004).
2291:
2258:
2234:
2208:"FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures"
2207:
2183:
2150:
2105:
2080:
2004:
1979:
1955:
1930:
1901:
1868:
1844:
1817:
1747:
1722:
1698:
1673:
1532:
1505:
1481:
1456:
1167:
1073:
1017:
3765:
3697:
3680:
3429:
3404:
3378:
3361:
3272:
3242:
3225:
2654:
2629:
2472:
2447:
2423:
2406:
2380:
2332:
2315:
2056:
2031:
1793:
1776:
1401:
1384:
508:
503:
498:
493:
488:
483:
478:
473:
468:
463:
458:
453:
448:
443:
427:
422:
417:
412:
407:
402:
386:
381:
3828:
3072:
2893:
2463:
2032:"Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice"
1424:
Sharp, Michael F.; Bythell-Douglas, Rohan; Deans, Andrew J.; Crismani, Wayne (2021).
1025:
911:
368:
3743:
3679:
Vandenberg CJ, Gergely F, Ong CY, Pace P, Mallery DL, Hiom K, Patel KJ (July 2003).
3531:
3395:
3352:
2405:
Vandenberg CJ, Gergely F, Ong CY, Pace P, Mallery DL, Hiom K, Patel KJ (July 2003).
2349:
69:
3621:
3576:
3039:
3008:
2958:
2941:
2888:
2841:
1674:"PALB2: the hub of a network of tumor suppressors involved in DNA damage responses"
1506:"The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways"
1101:
226:
106:
3403:
Pace P, Johnson M, Tan WM, Mosedale G, Sng C, Hoatlin M, et al. (July 2002).
2628:
Pace P, Johnson M, Tan WM, Mosedale G, Sng C, Hoatlin M, et al. (July 2002).
2448:"Functional interaction of monoubiquitinated FANCD2 and BRCA2/FANCD1 in chromatin"
1608:
1591:
1369:
2149:
Sharp MF, Murphy VJ, Twest SV, Tan W, Lui J, Simpson KJ, et al. (May 2020).
1995:
1946:
1568:
1441:
1076:
is a disorder with a recessive
Mendelian pattern of inheritance characterized by
93:
3781:
Wang X, Kennedy RD, Ray K, Stuckert P, Ellenberger T, D'Andrea AD (April 2007).
3362:"Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways"
3306:
3289:
2316:"Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways"
1689:
1327:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1309:
National Center for Biotechnology Information, U.S. National Library of Medicine
3642:
3464:
3447:
2606:
2174:
1649:
1632:
2975:
2796:
2743:
2735:
2134:
1085:
1081:
1021:
123:
73:
2282:
2224:
1892:
1522:
1183:
1133:
1089:
1036:
and FANCD2 CHEK2 phosphorylates BRCA1. Ubiquinated FANCD2 complexes with
1029:
538:
326:
247:
192:
179:
81:
3816:
3773:
3735:
3706:
3671:
3650:
3613:
3568:
3523:
3494:
3473:
3438:
3420:
3387:
3344:
3315:
3280:
3251:
3216:
2690:
2663:
2645:
2614:
2579:
2560:
2525:
2481:
2432:
2388:
2341:
2300:
2243:
2192:
2114:
2096:
2065:
2013:
1964:
1910:
1867:
Lachaud C, Moreno A, Marchesi F, Toth R, Blow JJ, Rouse J (February 2016).
1853:
1802:
1756:
1707:
1658:
1617:
1576:
1541:
1490:
1410:
3226:"Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway"
1777:"Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway"
1472:
1361:
1032:
the downstream targets FANCD2 and FANCI. ATM activates (phosphorylates)
884:
879:
3798:
3056:
2516:
2500:"Direct interaction of FANCD2 with BRCA2 in DNA damage response pathways"
2499:
1738:
1426:"The Fanconi anemia ubiquitin E3 ligase complex as an anti-cancer target"
868:
681:
662:
3605:
3560:
3323:
Grompe M (June 2002). "FANCD2: a branch-point in DNA damage response?".
2047:
1834:
3405:"FANCE: the link between Fanconi anaemia complex assembly and activity"
3336:
3003:
2755:
2630:"FANCE: the link between Fanconi anaemia complex assembly and activity"
1504:
Sobeck A, Stone S, Landais I, de Graaf B, Hoatlin ME (September 2009).
1353:
1171:
1146:
Mono-ubiquitination is also required for interaction with the nuclease
1053:
1045:
900:
648:
605:
2883:
2836:
2831:
1257:
1132:
proteins is required for the activation of the FANCD2 protein to the
1049:
991:
852:
560:
1011:
Recombinational repair of DNA double-strand damage - some key steps.
3727:
3515:
3198:
1178:
of meiotic chromosomes, activated FANCD2 protein co-localizes with
3143:
3138:
3133:
3123:
3116:
3111:
3106:
3101:
3096:
3086:
3081:
2936:
2900:
2821:
2816:
2811:
2801:
1251:
1245:
1239:
1233:
1222:
1179:
1140:
1129:
1125:
1121:
1117:
1113:
1109:
1105:
1097:
1093:
1061:
1057:
1041:
1037:
1033:
987:
979:
975:
971:
967:
963:
959:
955:
951:
947:
943:
939:
935:
931:
927:
923:
919:
915:
523:
519:
3029:
2985:
2980:
2915:
2910:
2905:
2878:
2858:
2853:
2806:
1263:
1151:
1147:
907:
61:
2708:
1457:"Susceptibility pathways in Fanconi's anemia and breast cancer"
2791:
2786:
1978:
Jamsai D, O'Connor AE, O'Donnell L, Lo JC, O'Bryan MK (2015).
2704:
1385:"Positional cloning of a novel Fanconi anemia gene, FANCD2"
1080:, hypersensitivity to DNA crosslinking agents, increased
2206:
Yuan F, El Hokayem J, Zhou W, Zhang Y (September 2009).
216:
1678:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
474:
regulation of DNA-binding transcription factor activity
338:
3017:
2996:
2924:
2869:
2742:
1929:Parmar K, D'Andrea A, Niedernhofer LJ (July 2009).
1721:Chun J, Buechelmaier ES, Powell SN (January 2013).
811:
770:
740:
699:
1283:
1281:
1279:
1770:
1768:
1766:
163:
2446:Wang X, Andreassen PR, D'Andrea AD (July 2004).
1166:In the non-mutant mouse, FANCD2 is expressed in
2537:
2535:
2493:
2491:
2400:
2398:
2361:
2359:
1672:Park JY, Zhang F, Andreassen PR (August 2014).
1590:Stolz A, Ertych N, Bastians H (February 2011).
1024:. DNA double-strand damages also activate the
484:regulation of regulatory T cell differentiation
16:Protein-coding gene in the species Homo sapiens
2025:
2023:
2720:
8:
3681:"BRCA1-independent ubiquitination of FANCD2"
2407:"BRCA1-independent ubiquitination of FANCD2"
1028:(FANCA/B/C/E/F/G/L/M). The FA core complex
910:. The Fanconi anemia complementation group (
1288:GRCh38: Ensembl release 89: ENSG00000144554
2727:
2713:
2705:
767:
696:
534:
364:
204:
101:
3806:
3696:
3463:
3428:
3377:
3305:
3241:
3206:
2653:
2569:
2559:
2515:
2471:
2422:
2331:
2290:
2233:
2223:
2182:
2133:
2104:
2055:
2003:
1954:
1924:
1922:
1920:
1900:
1843:
1833:
1792:
1746:
1697:
1648:
1607:
1531:
1521:
1480:
1400:
930:(also called BRCA2), FANCD2 (this gene),
494:neuronal stem cell population maintenance
1005:
469:cellular response to DNA damage stimulus
454:homologous chromosome pairing at meiosis
1275:
3483:The Israel Medical Association Journal
18:
504:cellular response to oxidative stress
168:
127:
122:
7:
479:regulation of CD40 signaling pathway
2548:The Journal of Biological Chemistry
2212:The Journal of Biological Chemistry
1510:The Journal of Biological Chemistry
1461:The New England Journal of Medicine
1020:that is recruited and activated by
499:regulation of inflammatory response
3187:American Journal of Human Genetics
3035:Proliferating Cell Nuclear Antigen
2966:Microhomology-mediated end joining
808:
737:
672:
653:
629:
610:
584:
565:
343:
304:
242:
221:
14:
903:that in humans is encoded by the
3157:
3156:
3050:Meiotic recombination checkpoint
2464:10.1128/MCB.24.13.5850-5862.2004
1931:"Mouse models of Fanconi anemia"
152:
145:
139:
114:
897:Fanconi anemia group D2 protein
3787:Molecular and Cellular Biology
2452:Molecular and Cellular Biology
1727:Molecular and Cellular Biology
327:More reference expression data
1:
3766:10.1016/S0014-4827(03)00261-1
3698:10.1016/S1097-2765(03)00281-8
3379:10.1016/S0092-8674(02)00747-X
3273:10.1016/S1471-4914(01)02178-5
3243:10.1016/S1097-2765(01)00173-3
2424:10.1016/S1097-2765(03)00281-8
2381:10.1016/S0014-4827(03)00261-1
2333:10.1016/S0092-8674(02)00747-X
1794:10.1016/s1097-2765(01)00173-3
1609:10.1158/1078-0432.CCR-10-1215
1402:10.1016/S1097-2765(01)00172-1
1228:Ataxia telangiectasia mutated
464:interstrand cross-link repair
137:
3261:Trends in Molecular Medicine
2932:Transcription-coupled repair
1996:10.4161/21565562.2014.979061
1947:10.1016/j.mrfmmm.2009.03.015
1569:10.1016/j.dnarep.2011.02.007
1442:10.1016/j.molcel.2021.04.023
3835:Genes on human chromosome 3
1690:10.1016/j.bbcan.2014.06.003
1026:Fanconi anemia core complex
459:response to gamma radiation
3856:
3754:Experimental Cell Research
3643:10.1182/blood-2002-11-3517
3465:10.1182/blood-2002-01-0278
2954:Non-homologous end joining
2778:Nucleotide excision repair
2771:Poly ADP ribose polymerase
2607:10.1182/blood-2002-11-3517
2369:Experimental Cell Research
2175:10.1038/s41598-020-64868-7
1650:10.1182/blood-2002-01-0278
1066:homologous recombinational
290:mucosa of transverse colon
3307:10.1093/carcin/22.12.1939
3152:
2135:10.1101/2020.09.10.291278
2085:British Journal of Cancer
1323:"Mouse PubMed Reference:"
1305:"Human PubMed Reference:"
1214:FANCD2 has been shown to
883:
878:
874:
867:
851:
834:
815:
794:
763:
744:
723:
692:
679:
675:
660:
656:
647:
636:
632:
617:
613:
604:
591:
587:
572:
568:
559:
544:
537:
533:
517:
367:
363:
351:
346:
337:
324:
311:
307:
254:
245:
215:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
2949:Homology directed repair
2871:Homologous recombination
2504:Human Molecular Genetics
1596:Clinical Cancer Research
1455:D'Andrea AD (May 2010).
1022:DNA double-strand breaks
2283:10.1126/science.1205805
2225:10.1074/jbc.m109.016006
2036:Genes & Development
1893:10.1126/science.aad5634
1523:10.1074/jbc.M109.007690
1078:chromosomal instability
2971:Postreplication repair
2766:Uracil-DNA glycosylase
2561:10.1074/jbc.M709076200
2097:10.1038/sj.bjc.6604362
1176:synaptonemal complexes
1070:
1064:plays a major role in
840:Chr 3: 10.03 – 10.1 Mb
387:DNA polymerase binding
1473:10.1056/NEJMra0809889
1190:Clinical significance
1009:
914:) currently includes
3799:10.1128/MCB.02357-06
3421:10.1093/emboj/cdf355
3077:core protein complex
2752:Base excision repair
2646:10.1093/emboj/cdf355
1739:10.1128/MCB.00465-12
1082:chromosomal breakage
418:condensed chromosome
130:Chromosome 3 (human)
3606:10.1038/nature01446
3598:2003Natur.421..961S
3561:10.1038/nature01445
3553:2003Natur.421..952G
3504:Nature Cell Biology
2849:DNA mismatch repair
2275:2011Sci...333..312J
2167:2020NatSR..10.7959S
2048:10.1101/gad.1103403
1885:2016Sci...351..846L
1835:10.7554/eLife.54128
1104:complex containing
489:brain morphogenesis
278:ganglionic eminence
3337:10.1038/nm0602-555
2517:10.1093/hmg/ddh135
2155:Scientific Reports
1354:10.1038/ng1195-341
1134:mono-ubiquitinated
1071:
437:Biological process
396:Cellular component
375:Molecular function
286:buccal mucosa cell
94:FANCD2 - orthologs
3170:
3169:
3045:Adaptive response
1935:Mutation Research
1436:(11): 2278–2289.
1090:monoubiquitinated
1030:monoubiquitinates
894:
893:
890:
889:
863:
862:
830:
829:
805:
804:
759:
758:
734:
733:
688:
687:
669:
668:
643:
642:
626:
625:
600:
599:
581:
580:
529:
528:
449:gamete generation
359:
358:
355:
354:
333:
332:
320:
319:
301:
300:
282:bone marrow cells
199:
198:
3847:
3820:
3810:
3777:
3747:
3710:
3700:
3675:
3654:
3625:
3580:
3535:
3498:
3477:
3467:
3442:
3432:
3409:The EMBO Journal
3399:
3381:
3356:
3319:
3309:
3284:
3255:
3245:
3220:
3210:
3160:
3159:
2729:
2722:
2715:
2706:
2695:
2694:
2674:
2668:
2667:
2657:
2634:The EMBO Journal
2625:
2619:
2618:
2590:
2584:
2583:
2573:
2563:
2539:
2530:
2529:
2519:
2495:
2486:
2485:
2475:
2443:
2437:
2436:
2426:
2402:
2393:
2392:
2363:
2354:
2353:
2335:
2311:
2305:
2304:
2294:
2254:
2248:
2247:
2237:
2227:
2218:(36): 24443–52.
2203:
2197:
2196:
2186:
2146:
2140:
2139:
2137:
2125:
2119:
2118:
2108:
2076:
2070:
2069:
2059:
2027:
2018:
2017:
2007:
1975:
1969:
1968:
1958:
1926:
1915:
1914:
1904:
1864:
1858:
1857:
1847:
1837:
1813:
1807:
1806:
1796:
1772:
1761:
1760:
1750:
1718:
1712:
1711:
1701:
1669:
1663:
1662:
1652:
1628:
1622:
1621:
1611:
1587:
1581:
1580:
1552:
1546:
1545:
1535:
1525:
1501:
1495:
1494:
1484:
1452:
1446:
1445:
1421:
1415:
1414:
1404:
1380:
1374:
1373:
1337:
1331:
1330:
1319:
1313:
1312:
1301:
1295:
1285:
1084:, and defective
876:
875:
847:
842:
825:
809:
800:
768:
764:RefSeq (protein)
754:
738:
729:
697:
673:
654:
630:
611:
585:
566:
535:
365:
344:
329:
305:
266:secondary oocyte
262:ventricular zone
250:
248:Top expressed in
243:
222:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
47:
40:
19:
3855:
3854:
3850:
3849:
3848:
3846:
3845:
3844:
3825:
3824:
3823:
3793:(8): 3098–108.
3780:
3750:
3716:Nature Genetics
3713:
3678:
3666:(14): 4204–10.
3660:Cancer Research
3657:
3628:
3592:(6926): 961–6.
3583:
3547:(6926): 952–6.
3538:
3501:
3480:
3445:
3415:(13): 3414–23.
3402:
3359:
3325:Nature Medicine
3322:
3300:(12): 1939–46.
3287:
3258:
3223:
3180:
3176:
3174:Further reading
3171:
3166:
3148:
3018:Other/ungrouped
3013:
2992:
2920:
2865:
2761:DNA glycosylase
2744:Excision repair
2738:
2733:
2703:
2698:
2685:(14): 4204–10.
2679:Cancer Research
2676:
2675:
2671:
2640:(13): 3414–23.
2627:
2626:
2622:
2592:
2591:
2587:
2554:(15): 9844–51.
2541:
2540:
2533:
2497:
2496:
2489:
2458:(13): 5850–62.
2445:
2444:
2440:
2404:
2403:
2396:
2365:
2364:
2357:
2313:
2312:
2308:
2269:(6040): 312–6.
2256:
2255:
2251:
2205:
2204:
2200:
2148:
2147:
2143:
2127:
2126:
2122:
2091:(10): 1653–61.
2078:
2077:
2073:
2042:(16): 2021–35.
2029:
2028:
2021:
1984:Spermatogenesis
1977:
1976:
1972:
1941:(1–2): 133–40.
1928:
1927:
1918:
1879:(6275): 846–9.
1866:
1865:
1861:
1815:
1814:
1810:
1774:
1773:
1764:
1720:
1719:
1715:
1671:
1670:
1666:
1630:
1629:
1625:
1589:
1588:
1584:
1554:
1553:
1549:
1516:(38): 25560–8.
1503:
1502:
1498:
1467:(20): 1909–19.
1454:
1453:
1449:
1423:
1422:
1418:
1382:
1381:
1377:
1342:Nature Genetics
1339:
1338:
1334:
1321:
1320:
1316:
1303:
1302:
1298:
1286:
1277:
1273:
1212:
1200:
1192:
1160:
1004:
994:, and probably
885:View/Edit Mouse
880:View/Edit Human
845:
838:
835:Location (UCSC)
821:
817:
796:
790:
786:
782:
778:
774:
750:
746:
725:
719:
715:
711:
707:
703:
620:ENSG00000144554
513:
432:
391:
382:protein binding
325:
316:
297:
292:
288:
284:
280:
276:
272:
268:
264:
260:
246:
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
3853:
3851:
3843:
3842:
3840:Human proteins
3837:
3827:
3826:
3822:
3821:
3778:
3748:
3728:10.1038/ng1241
3711:
3685:Molecular Cell
3676:
3655:
3626:
3581:
3536:
3516:10.1038/ncb879
3510:(12): 913–20.
3499:
3489:(10): 819–23.
3478:
3458:(7): 2414–20.
3443:
3400:
3357:
3320:
3294:Carcinogenesis
3285:
3256:
3230:Molecular Cell
3221:
3199:10.1086/302896
3193:(5): 1540–51.
3177:
3175:
3172:
3168:
3167:
3165:
3164:
3153:
3150:
3149:
3147:
3146:
3141:
3136:
3131:
3126:
3121:
3120:
3119:
3114:
3109:
3104:
3099:
3094:
3089:
3084:
3069:
3068:
3063:
3053:
3052:
3047:
3042:
3037:
3032:
3027:
3021:
3019:
3015:
3014:
3012:
3011:
3006:
3000:
2998:
2994:
2993:
2991:
2990:
2989:
2988:
2983:
2973:
2968:
2963:
2962:
2961:
2951:
2946:
2945:
2944:
2939:
2928:
2926:
2925:Other pathways
2922:
2921:
2919:
2918:
2913:
2908:
2903:
2898:
2897:
2896:
2886:
2881:
2875:
2873:
2867:
2866:
2864:
2863:
2862:
2861:
2856:
2846:
2845:
2844:
2839:
2834:
2829:
2824:
2819:
2814:
2809:
2804:
2799:
2794:
2789:
2775:
2774:
2773:
2768:
2763:
2748:
2746:
2740:
2739:
2734:
2732:
2731:
2724:
2717:
2709:
2702:
2701:External links
2699:
2697:
2696:
2669:
2620:
2585:
2531:
2510:(12): 1241–8.
2487:
2438:
2411:Molecular Cell
2394:
2355:
2306:
2249:
2198:
2141:
2120:
2071:
2019:
1990:(1): e979061.
1970:
1916:
1859:
1808:
1781:Molecular Cell
1762:
1713:
1664:
1643:(7): 2414–20.
1623:
1582:
1547:
1496:
1447:
1430:Molecular Cell
1416:
1389:Molecular Cell
1375:
1332:
1314:
1296:
1274:
1272:
1269:
1268:
1267:
1261:
1255:
1249:
1243:
1237:
1231:
1225:
1211:
1208:
1199:
1196:
1191:
1188:
1159:
1156:
1074:Fanconi anemia
1018:protein kinase
1003:
1000:
892:
891:
888:
887:
882:
872:
871:
865:
864:
861:
860:
858:
856:
849:
848:
843:
836:
832:
831:
828:
827:
813:
812:
806:
803:
802:
792:
791:
765:
761:
760:
757:
756:
742:
741:
735:
732:
731:
721:
720:
694:
690:
689:
686:
685:
677:
676:
670:
667:
666:
658:
657:
651:
645:
644:
641:
640:
634:
633:
627:
624:
623:
615:
614:
608:
602:
601:
598:
597:
589:
588:
582:
579:
578:
570:
569:
563:
557:
556:
551:
546:
542:
541:
531:
530:
527:
526:
515:
514:
512:
511:
506:
501:
496:
491:
486:
481:
476:
471:
466:
461:
456:
451:
446:
440:
438:
434:
433:
431:
430:
425:
420:
415:
410:
405:
399:
397:
393:
392:
390:
389:
384:
378:
376:
372:
371:
361:
360:
357:
356:
353:
352:
349:
348:
341:
335:
334:
331:
330:
322:
321:
318:
317:
315:
312:
309:
308:
302:
299:
298:
296:
295:
291:
287:
283:
279:
275:
271:
267:
263:
259:
255:
252:
251:
239:
238:
230:
219:
213:
212:
209:RNA expression
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
3852:
3841:
3838:
3836:
3833:
3832:
3830:
3818:
3814:
3809:
3804:
3800:
3796:
3792:
3788:
3784:
3779:
3775:
3771:
3767:
3763:
3760:(2): 211–21.
3759:
3755:
3749:
3745:
3741:
3737:
3733:
3729:
3725:
3722:(2): 165–70.
3721:
3717:
3712:
3708:
3704:
3699:
3694:
3691:(1): 247–54.
3690:
3686:
3682:
3677:
3673:
3669:
3665:
3661:
3656:
3652:
3648:
3644:
3640:
3637:(1): 136–41.
3636:
3632:
3627:
3623:
3619:
3615:
3611:
3607:
3603:
3599:
3595:
3591:
3587:
3582:
3578:
3574:
3570:
3566:
3562:
3558:
3554:
3550:
3546:
3542:
3537:
3533:
3529:
3525:
3521:
3517:
3513:
3509:
3505:
3500:
3496:
3492:
3488:
3484:
3479:
3475:
3471:
3466:
3461:
3457:
3453:
3449:
3444:
3440:
3436:
3431:
3426:
3422:
3418:
3414:
3410:
3406:
3401:
3397:
3393:
3389:
3385:
3380:
3375:
3372:(4): 459–72.
3371:
3367:
3363:
3358:
3354:
3350:
3346:
3342:
3338:
3334:
3330:
3326:
3321:
3317:
3313:
3308:
3303:
3299:
3295:
3291:
3286:
3282:
3278:
3274:
3270:
3267:(12): 560–5.
3266:
3262:
3257:
3253:
3249:
3244:
3239:
3236:(2): 249–62.
3235:
3231:
3227:
3222:
3218:
3214:
3209:
3204:
3200:
3196:
3192:
3188:
3184:
3179:
3178:
3173:
3163:
3155:
3154:
3151:
3145:
3142:
3140:
3137:
3135:
3132:
3130:
3127:
3125:
3122:
3118:
3115:
3113:
3110:
3108:
3105:
3103:
3100:
3098:
3095:
3093:
3090:
3088:
3085:
3083:
3080:
3079:
3078:
3074:
3073:FANC proteins
3071:
3070:
3067:
3064:
3062:
3058:
3055:
3054:
3051:
3048:
3046:
3043:
3041:
3038:
3036:
3033:
3031:
3028:
3026:
3023:
3022:
3020:
3016:
3010:
3007:
3005:
3002:
3001:
2999:
2995:
2987:
2984:
2982:
2979:
2978:
2977:
2974:
2972:
2969:
2967:
2964:
2960:
2957:
2956:
2955:
2952:
2950:
2947:
2943:
2940:
2938:
2935:
2934:
2933:
2930:
2929:
2927:
2923:
2917:
2914:
2912:
2909:
2907:
2904:
2902:
2899:
2895:
2894:RecQ helicase
2892:
2891:
2890:
2887:
2885:
2882:
2880:
2877:
2876:
2874:
2872:
2868:
2860:
2857:
2855:
2852:
2851:
2850:
2847:
2843:
2840:
2838:
2835:
2833:
2830:
2828:
2825:
2823:
2820:
2818:
2815:
2813:
2810:
2808:
2805:
2803:
2800:
2798:
2795:
2793:
2790:
2788:
2785:
2784:
2783:
2779:
2776:
2772:
2769:
2767:
2764:
2762:
2759:
2758:
2757:
2753:
2750:
2749:
2747:
2745:
2741:
2737:
2730:
2725:
2723:
2718:
2716:
2711:
2710:
2707:
2700:
2692:
2688:
2684:
2680:
2673:
2670:
2665:
2661:
2656:
2651:
2647:
2643:
2639:
2635:
2631:
2624:
2621:
2616:
2612:
2608:
2604:
2601:(1): 136–41.
2600:
2596:
2589:
2586:
2581:
2577:
2572:
2567:
2562:
2557:
2553:
2549:
2545:
2538:
2536:
2532:
2527:
2523:
2518:
2513:
2509:
2505:
2501:
2494:
2492:
2488:
2483:
2479:
2474:
2469:
2465:
2461:
2457:
2453:
2449:
2442:
2439:
2434:
2430:
2425:
2420:
2417:(1): 247–54.
2416:
2412:
2408:
2401:
2399:
2395:
2390:
2386:
2382:
2378:
2375:(2): 211–21.
2374:
2370:
2362:
2360:
2356:
2351:
2347:
2343:
2339:
2334:
2329:
2326:(4): 459–72.
2325:
2321:
2317:
2310:
2307:
2302:
2298:
2293:
2288:
2284:
2280:
2276:
2272:
2268:
2264:
2260:
2253:
2250:
2245:
2241:
2236:
2231:
2226:
2221:
2217:
2213:
2209:
2202:
2199:
2194:
2190:
2185:
2180:
2176:
2172:
2168:
2164:
2160:
2156:
2152:
2145:
2142:
2136:
2131:
2124:
2121:
2116:
2112:
2107:
2102:
2098:
2094:
2090:
2086:
2082:
2075:
2072:
2067:
2063:
2058:
2053:
2049:
2045:
2041:
2037:
2033:
2026:
2024:
2020:
2015:
2011:
2006:
2001:
1997:
1993:
1989:
1985:
1981:
1974:
1971:
1966:
1962:
1957:
1952:
1948:
1944:
1940:
1936:
1932:
1925:
1923:
1921:
1917:
1912:
1908:
1903:
1898:
1894:
1890:
1886:
1882:
1878:
1874:
1870:
1863:
1860:
1855:
1851:
1846:
1841:
1836:
1831:
1827:
1823:
1819:
1812:
1809:
1804:
1800:
1795:
1790:
1787:(2): 249–62.
1786:
1782:
1778:
1771:
1769:
1767:
1763:
1758:
1754:
1749:
1744:
1740:
1736:
1733:(2): 387–95.
1732:
1728:
1724:
1717:
1714:
1709:
1705:
1700:
1695:
1691:
1687:
1684:(1): 263–75.
1683:
1679:
1675:
1668:
1665:
1660:
1656:
1651:
1646:
1642:
1638:
1634:
1627:
1624:
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1615:
1610:
1605:
1601:
1597:
1593:
1586:
1583:
1578:
1574:
1570:
1566:
1563:(5): 518–25.
1562:
1558:
1551:
1548:
1543:
1539:
1534:
1529:
1524:
1519:
1515:
1511:
1507:
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1209:
1207:
1204:
1197:
1195:
1189:
1187:
1185:
1181:
1177:
1173:
1169:
1168:spermatogonia
1164:
1157:
1155:
1153:
1149:
1144:
1142:
1137:
1135:
1131:
1127:
1123:
1119:
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1111:
1107:
1103:
1099:
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1087:
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1079:
1075:
1067:
1063:
1059:
1055:
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1031:
1027:
1023:
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1008:
1001:
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993:
989:
985:
981:
977:
973:
969:
965:
961:
957:
953:
949:
945:
941:
937:
933:
929:
925:
921:
917:
913:
909:
906:
902:
898:
886:
881:
877:
873:
870:
866:
859:
857:
854:
850:
844:
841:
837:
833:
826:
824:
820:
814:
810:
807:
801:
799:
793:
789:
785:
781:
777:
773:
769:
766:
762:
755:
753:
749:
743:
739:
736:
730:
728:
722:
718:
714:
710:
706:
702:
698:
695:
693:RefSeq (mRNA)
691:
684:
683:
678:
674:
671:
665:
664:
659:
655:
652:
650:
646:
639:
635:
631:
628:
622:
621:
616:
612:
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583:
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571:
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547:
543:
540:
536:
532:
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516:
510:
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477:
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401:
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398:
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383:
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370:
369:Gene ontology
366:
362:
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345:
342:
340:
336:
328:
323:
313:
310:
306:
303:
293:
289:
285:
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244:
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218:
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194:
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176:
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162:
155:
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142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
3790:
3786:
3757:
3753:
3719:
3715:
3688:
3684:
3663:
3659:
3634:
3630:
3589:
3585:
3544:
3540:
3507:
3503:
3486:
3482:
3455:
3451:
3412:
3408:
3369:
3365:
3331:(6): 555–6.
3328:
3324:
3297:
3293:
3264:
3260:
3233:
3229:
3190:
3186:
3128:
3076:
3057:DNA helicase
3040:8-Oxoguanine
3009:SOS response
2889:RecF pathway
2842:Excinuclease
2682:
2678:
2672:
2637:
2633:
2623:
2598:
2594:
2588:
2551:
2547:
2507:
2503:
2455:
2451:
2441:
2414:
2410:
2372:
2368:
2323:
2319:
2309:
2266:
2262:
2252:
2215:
2211:
2201:
2158:
2154:
2144:
2123:
2088:
2084:
2074:
2039:
2035:
1987:
1983:
1973:
1938:
1934:
1876:
1872:
1862:
1825:
1821:
1811:
1784:
1780:
1730:
1726:
1716:
1681:
1677:
1667:
1640:
1636:
1626:
1602:(3): 401–5.
1599:
1595:
1585:
1560:
1556:
1550:
1513:
1509:
1499:
1464:
1460:
1450:
1433:
1429:
1419:
1395:(2): 241–8.
1392:
1388:
1378:
1348:(3): 341–3.
1345:
1341:
1335:
1326:
1317:
1308:
1299:
1213:
1210:Interactions
1205:
1201:
1193:
1165:
1161:
1145:
1138:
1072:
1010:
904:
896:
895:
823:NP_001334279
819:NP_001028416
816:
798:NP_001361184
795:
788:NP_001361183
784:NP_001361182
776:NP_001306913
772:NP_001018125
752:NM_001347350
748:NM_001033244
745:
727:NM_001374255
724:
717:NM_001374254
713:NM_001374253
709:NM_001319984
701:NM_001018115
680:
661:
637:
618:
592:
573:
553:
548:
428:nuclear body
270:right testis
232:
225:
53:External IDs
2161:(1): 7959.
1158:Infertility
1016:(ATM) is a
413:nucleoplasm
274:left testis
191:10,101,932
178:10,026,370
31:Identifiers
3829:Categories
2997:Regulation
2976:Photolyase
2736:DNA repair
1557:DNA Repair
1294:, May 2017
1271:References
1086:DNA repair
509:DNA repair
444:cell cycle
236:(ortholog)
74:HomoloGene
2817:XPG/ERCC5
2802:XPD/ERCC2
1184:germ cell
1136:isoform.
780:NP_149075
705:NM_033084
539:Orthologs
403:nucleolus
82:GeneCards
3817:17296736
3774:14499622
3744:10149290
3736:12973351
3707:12887909
3672:12874027
3651:12649160
3614:12607005
3569:12607003
3532:20807784
3524:12447395
3495:12389351
3474:12239151
3439:12093742
3396:16580666
3388:12086603
3353:27843912
3345:12042798
3316:11751423
3281:11733219
3252:11239454
3217:10762542
3162:Category
2812:XPF/DDB1
2807:XPE/DDB1
2691:12874027
2664:12093742
2615:12649160
2580:18263878
2526:15115758
2482:15199141
2433:12887909
2389:14499622
2350:16580666
2342:12086603
2301:21764741
2244:19561358
2193:32409752
2115:18475298
2066:12893777
2014:26413409
1965:19427003
1911:26797144
1854:32167469
1803:11239454
1757:23149936
1708:24998779
1659:12239151
1618:21088254
1577:21466974
1542:19633289
1491:20484397
1411:11239453
1290:–
1216:interact
1069:process.
1002:Function
869:Wikidata
518:Sources:
258:testicle
3808:1899922
3622:4410773
3594:Bibcode
3577:4301037
3549:Bibcode
3208:1378015
3004:SOS box
2756:AP site
2571:2398728
2292:3310437
2271:Bibcode
2263:Science
2235:2782037
2184:7224301
2163:Bibcode
2130:bioRxiv
2106:2391131
2005:4581071
1956:2778466
1902:4770513
1881:Bibcode
1873:Science
1845:7156235
1748:3554112
1699:4183126
1533:2757957
1482:3069698
1362:7581463
1292:Ensembl
1172:meiosis
1102:nuclear
901:protein
649:UniProt
606:Ensembl
545:Species
524:QuickGO
423:cytosol
408:nucleus
211:pattern
70:2448480
38:Aliases
3815:
3805:
3772:
3742:
3734:
3705:
3670:
3649:
3620:
3612:
3586:Nature
3575:
3567:
3541:Nature
3530:
3522:
3493:
3472:
3437:
3430:125396
3427:
3394:
3386:
3351:
3343:
3314:
3279:
3250:
3215:
3205:
3129:FANCD2
3124:FANCD1
2884:RecBCD
2837:RAD23B
2832:RAD23A
2689:
2662:
2655:125396
2652:
2613:
2578:
2568:
2524:
2480:
2473:480901
2470:
2431:
2387:
2348:
2340:
2299:
2289:
2242:
2232:
2191:
2181:
2132:
2113:
2103:
2064:
2057:196256
2054:
2012:
2002:
1963:
1953:
1909:
1899:
1852:
1842:
1801:
1755:
1745:
1706:
1696:
1657:
1616:
1575:
1540:
1530:
1489:
1479:
1409:
1370:451042
1368:
1360:
1258:HTATIP
1218:with:
1198:Cancer
1174:. In
1054:RAD51D
1050:RAD51C
1046:RAD51B
928:FANCD1
905:FANCD2
855:search
853:PubMed
682:Q80V62
663:Q9BXW9
594:211651
561:Entrez
339:BioGPS
170:3p25.3
86:FANCD2
62:613984
45:FANCD2
22:FANCD2
3740:S2CID
3631:Blood
3618:S2CID
3573:S2CID
3528:S2CID
3452:Blood
3392:S2CID
3349:S2CID
3144:FANCN
3139:FANCJ
3134:FANCI
3117:FANCM
3112:FANCL
3107:FANCG
3102:FANCF
3097:FANCE
3092:FANCC
3087:FANCB
3082:FANCA
2942:ERCC8
2937:ERCC6
2901:RAD51
2822:ERCC1
2595:Blood
2346:S2CID
1822:eLife
1637:Blood
1366:S2CID
1260:, and
1252:FANCE
1246:BRCA2
1240:BRCA1
1234:BARD1
1223:FANCI
1180:BRCA1
1141:FANCI
1130:FANCG
1126:FANCL
1122:FANCF
1118:FANCE
1114:FANCC
1110:FANCB
1106:FANCA
1098:BRCA2
1094:BRCA1
1062:RAD51
1058:XRCC2
1042:RAD51
1038:BRCA1
1034:CHEK2
996:FANCW
992:FANCV
988:FANCU
984:FANCT
980:FANCS
976:FANCR
972:FANCQ
968:FANCP
964:FANCO
960:FANCN
956:FANCM
952:FANCL
948:FANCJ
944:FANCI
940:FANCG
936:FANCF
932:FANCE
924:FANCC
920:FANCB
916:FANCA
899:is a
554:Mouse
549:Human
520:Amigo
294:gonad
234:Mouse
227:Human
174:Start
107:Human
78:13212
3813:PMID
3770:PMID
3732:PMID
3703:PMID
3668:PMID
3647:PMID
3610:PMID
3565:PMID
3520:PMID
3491:PMID
3470:PMID
3435:PMID
3384:PMID
3366:Cell
3341:PMID
3312:PMID
3277:PMID
3248:PMID
3213:PMID
3030:PcrA
2986:CRY2
2981:CRY1
2916:LexA
2911:Slx4
2906:Sgs1
2879:RecA
2859:MSH2
2854:MLH1
2782:ERCC
2687:PMID
2660:PMID
2611:PMID
2576:PMID
2522:PMID
2478:PMID
2429:PMID
2385:PMID
2338:PMID
2320:Cell
2297:PMID
2240:PMID
2189:PMID
2111:PMID
2062:PMID
2010:PMID
1961:PMID
1907:PMID
1850:PMID
1799:PMID
1753:PMID
1704:PMID
1682:1846
1655:PMID
1614:PMID
1573:PMID
1538:PMID
1487:PMID
1407:PMID
1358:PMID
1264:MEN1
1152:FAN1
1148:FAN1
1128:and
1108:, ,
1096:and
1040:and
912:FANC
908:gene
575:2177
217:Bgee
165:Band
124:Chr.
58:OMIM
3803:PMC
3795:doi
3762:doi
3758:289
3724:doi
3693:doi
3639:doi
3635:102
3602:doi
3590:421
3557:doi
3545:421
3512:doi
3460:doi
3456:100
3425:PMC
3417:doi
3374:doi
3370:109
3333:doi
3302:doi
3269:doi
3238:doi
3203:PMC
3195:doi
3066:WRN
3061:BLM
3025:Ogt
2827:RPA
2797:XPC
2792:XPB
2787:XPA
2650:PMC
2642:doi
2603:doi
2599:102
2566:PMC
2556:doi
2552:283
2512:doi
2468:PMC
2460:doi
2419:doi
2377:doi
2373:289
2328:doi
2324:109
2287:PMC
2279:doi
2267:333
2230:PMC
2220:doi
2216:284
2179:PMC
2171:doi
2101:PMC
2093:doi
2052:PMC
2044:doi
2000:PMC
1992:doi
1951:PMC
1943:doi
1939:668
1897:PMC
1889:doi
1877:351
1840:PMC
1830:doi
1789:doi
1743:PMC
1735:doi
1694:PMC
1686:doi
1645:doi
1641:100
1604:doi
1565:doi
1528:PMC
1518:doi
1514:284
1477:PMC
1469:doi
1465:362
1438:doi
1397:doi
1350:doi
1014:ATM
846:n/a
638:n/a
347:n/a
314:n/a
187:End
90:OMA
66:MGI
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