242:
219:
116:
141:
248:
147:
1849:
1280:
Alders, M; Al-Gazali, L; Cordeiro, I; Dallapiccola, B; Garavelli, L; Tuysuz, B; Salehi, F; Haagmans, M. A.; Mook, O. R.; Majoie, C. B.; Mannens, M. M.; Hennekam, R. C. (2014). "Hennekam syndrome can be caused by FAT4 mutations and be allelic to Van
Maldergem syndrome".
1195:
Höng JC, Ivanov NV, Hodor P, Xia M, Wei N, Blevins R, Gerhold D, Borodovsky M, Liu Y (March 2004). "Identification of new human cadherin genes using a combination of protein motif search and gene finding methods".
1689:
255:
154:
762:
743:
77:
1918:
1163:
1894:
1682:
1145:
1913:
986:
241:
1728:
993:
218:
1181:
1675:
1132:
1111:
1128:
140:
115:
1107:
57:
254:
153:
1887:
247:
146:
1505:"Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score"
1626:"A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration"
807:
65:
1710:
1702:
1071:
788:
1880:
1799:
1377:
948:
944:
129:
44:
1698:
936:
932:
881:
877:
1655:
1419:"Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder"
1306:
89:
969:
940:
906:
885:
1647:
1612:
1569:
1534:
1491:
1448:
1405:
1352:
1298:
1262:
1213:
1083:
37:
1864:
1667:
1736:
1637:
1602:
1594:
1559:
1524:
1516:
1481:
1473:
1438:
1430:
1395:
1385:
1342:
1290:
1252:
1244:
1205:
334:
265:
209:
164:
309:
85:
1381:
1607:
1582:
1529:
1504:
1486:
1461:
1443:
1418:
1400:
1365:
1257:
1232:
677:
672:
667:
662:
657:
652:
647:
642:
637:
632:
627:
622:
617:
612:
607:
602:
597:
592:
587:
571:
566:
561:
556:
551:
546:
530:
525:
1907:
512:
1659:
1462:"A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB"
1310:
69:
1860:
327:
106:
1390:
1366:"Genome-wide and candidate gene association study of cigarette smoking behaviors"
93:
48:, CDHF14, CDHR11, FAT-J, FATJ, NBLA00548, VMLDS2, HKLLS2, FAT atypical cadherin 4
1168:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1150:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1642:
1625:
1564:
1547:
1233:"Identification of Fat4 as a candidate tumor suppressor gene in breast cancers"
410:
1520:
1294:
1209:
226:
123:
73:
707:
470:
348:
293:
280:
192:
179:
81:
1651:
1616:
1573:
1538:
1495:
1452:
1409:
1356:
1302:
1266:
1217:
593:
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
1347:
1330:
1033:
1028:
1812:
1598:
1477:
1017:
852:
833:
1583:"Genome-wide association meta-analysis for total serum bilirubin levels"
1434:
613:
regulation of metanephric nephron tubule epithelial cell differentiation
1756:
1751:
1057:
819:
774:
1364:
Caporaso N, Gu F, Chatterjee N, et al. (2009). Reitsma PH (ed.).
1248:
1828:
1766:
1001:
729:
1848:
1784:
1779:
1741:
692:
688:
1856:
1807:
1789:
1774:
1746:
1064:
61:
1671:
598:
homophilic cell adhesion via plasma membrane adhesion molecules
1182:"Entrez Gene: FAT tumor suppressor homolog 4 (Drosophila)"
1548:"Phosphoproteomic analysis of the developing mouse brain"
1546:
Ballif BA, Villén J, Beausoleil SA, et al. (2004).
317:
1868:
1331:"Comparative integromics on FAT1, FAT2, FAT3 and FAT4"
1581:
Johnson AD, Kavousi M, Smith AV, et al. (2009).
482:
1821:
1798:
1765:
1727:
1709:
1417:Liu Y, Blackwood DH, Caesar S, et al. (2010).
962:
925:
899:
870:
663:
fibroblast growth factor receptor signaling pathway
1460:Need AC, Attix DK, McEvoy JM, et al. (2009).
1124:
1122:
1120:
1103:
1101:
1099:
633:inner ear receptor cell stereocilium organization
264:
163:
648:branching involved in ureteric bud morphogenesis
1503:Rose JE, Behm FM, Drgon T, et al. (2010).
16:Protein-coding gene in the species Homo sapiens
1129:GRCm38: Ensembl release 89: ENSMUSG00000046743
1888:
1683:
8:
1231:Qi C, Zhu YT, Hu L, Zhu YJ (February 2009).
1108:GRCh38: Ensembl release 89: ENSG00000196159
1895:
1881:
1690:
1676:
1668:
1624:Lim J, Hao T, Shaw C, et al. (2006).
703:
508:
305:
204:
101:
1641:
1606:
1563:
1528:
1485:
1442:
1399:
1389:
1346:
1256:
673:condensed mesenchymal cell proliferation
638:ossification involved in bone maturation
1095:
18:
269:
230:
225:
168:
127:
122:
7:
1845:
1843:
1082:Mutations in FAT4 are associated to
1867:. You can help Knowledge (XXG) by
959:
922:
896:
867:
843:
824:
798:
779:
753:
734:
562:intracellular anatomical structure
487:
405:
343:
322:
14:
1060:that in humans is encoded by the
1847:
253:
246:
240:
217:
152:
145:
139:
114:
1054:FAT tumor suppressor homolog 4
547:integral component of membrane
471:More reference expression data
1:
1919:Human chromosome 4 gene stubs
238:
137:
1391:10.1371/journal.pone.0004653
1070:FAT4 is associated with the
623:plasma membrane organization
1914:Genes on human chromosome 4
628:digestive tract development
588:cerebral cortex development
363:stromal cell of endometrium
1935:
1842:
1643:10.1016/j.cell.2006.03.032
1565:10.1074/mcp.M400085-MCP200
1521:10.2119/molmed.2009.00159
1329:Katoh Y, Katoh M (2006).
1295:10.1007/s00439-014-1456-y
1210:10.1016/j.jmb.2004.01.026
1164:"Mouse PubMed Reference:"
1146:"Human PubMed Reference:"
1050:cadherin family member 14
1032:
1027:
1023:
1016:
1000:
987:Chr 4: 125.31 – 125.49 Mb
981:
966:
929:
918:
903:
874:
863:
850:
846:
831:
827:
818:
805:
801:
786:
782:
773:
760:
756:
741:
737:
728:
713:
706:
702:
686:
511:
507:
495:
490:
481:
468:
417:
408:
379:Descending thoracic aorta
375:mucosa of paranasal sinus
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1703:Hippo signaling pathway
1072:Hippo signaling pathway
994:Chr 3: 38.94 – 39.07 Mb
668:Notch signaling pathway
429:external carotid artery
425:internal carotid artery
1552:Mol. Cell. Proteomics
1348:10.3892/ijmm.18.3.523
1078:Clinical significance
572:extracellular exosome
1800:Transcription factor
1423:Molecular Psychiatry
232:Chromosome 3 (mouse)
130:Chromosome 4 (human)
1435:10.1038/mp.2009.107
1382:2009PLoSO...4.4653C
1046:Protocadherin Fat 4
658:nephron development
608:heart morphogenesis
552:apical part of cell
531:calcium ion binding
445:conjunctival fornix
371:epithelium of colon
1855:This article on a
1599:10.1093/hmg/ddp202
1478:10.1093/hmg/ddp413
808:ENSMUSG00000046743
678:cell-cell adhesion
618:kidney development
581:Biological process
540:Cellular component
519:Molecular function
1876:
1875:
1837:
1836:
1699:Signaling pathway
1249:10.1002/ijc.23775
1084:Hennekam syndrome
1043:
1042:
1039:
1038:
1012:
1011:
977:
976:
956:
955:
914:
913:
893:
892:
859:
858:
840:
839:
814:
813:
795:
794:
769:
768:
750:
749:
698:
697:
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
367:periodontal fiber
300:
299:
199:
198:
1926:
1897:
1890:
1883:
1851:
1844:
1692:
1685:
1678:
1669:
1663:
1645:
1620:
1610:
1577:
1567:
1558:(11): 1093–101.
1542:
1532:
1499:
1489:
1456:
1446:
1413:
1403:
1393:
1360:
1350:
1335:Int. J. Mol. Med
1315:
1314:
1289:(9): 1161–1167.
1277:
1271:
1270:
1260:
1228:
1222:
1221:
1192:
1186:
1185:
1178:
1172:
1171:
1160:
1154:
1153:
1142:
1136:
1126:
1115:
1105:
1048:, also known as
1025:
1024:
996:
989:
972:
960:
951:
923:
919:RefSeq (protein)
909:
897:
888:
868:
844:
825:
799:
780:
754:
735:
704:
509:
488:
473:
413:
411:Top expressed in
406:
391:ventricular zone
383:popliteal artery
351:
349:Top expressed in
344:
323:
306:
296:
283:
272:
257:
250:
244:
233:
221:
205:
195:
182:
171:
156:
149:
143:
132:
118:
102:
96:
94:FAT4 - orthologs
47:
40:
19:
1934:
1933:
1929:
1928:
1927:
1925:
1924:
1923:
1904:
1903:
1902:
1901:
1840:
1838:
1833:
1817:
1794:
1761:
1729:Adaptor protein
1723:
1705:
1696:
1666:
1623:
1593:(14): 2700–10.
1587:Hum. Mol. Genet
1580:
1545:
1515:(7–8): 247–53.
1502:
1472:(23): 4650–61.
1466:Hum. Mol. Genet
1459:
1416:
1363:
1328:
1324:
1322:Further reading
1319:
1318:
1279:
1278:
1274:
1230:
1229:
1225:
1194:
1193:
1189:
1180:
1179:
1175:
1162:
1161:
1157:
1144:
1143:
1139:
1127:
1118:
1106:
1097:
1092:
1080:
1034:View/Edit Mouse
1029:View/Edit Human
992:
985:
982:Location (UCSC)
968:
947:
943:
939:
935:
931:
905:
884:
880:
876:
789:ENSG00000196159
682:
643:hippo signaling
576:
567:plasma membrane
535:
526:protein binding
469:
460:
455:
453:ascending aorta
451:
447:
443:
439:
435:
431:
427:
423:
409:
398:
393:
389:
387:tibial arteries
385:
381:
377:
373:
369:
365:
361:
359:Achilles tendon
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1932:
1930:
1922:
1921:
1916:
1906:
1905:
1900:
1899:
1892:
1885:
1877:
1874:
1873:
1852:
1835:
1834:
1832:
1831:
1825:
1823:
1819:
1818:
1816:
1815:
1810:
1804:
1802:
1796:
1795:
1793:
1792:
1787:
1782:
1777:
1771:
1769:
1763:
1762:
1760:
1759:
1754:
1749:
1744:
1739:
1733:
1731:
1725:
1724:
1722:
1721:
1715:
1713:
1707:
1706:
1697:
1695:
1694:
1687:
1680:
1672:
1665:
1664:
1621:
1578:
1543:
1500:
1457:
1414:
1361:
1325:
1323:
1320:
1317:
1316:
1283:Human Genetics
1272:
1237:Int. J. Cancer
1223:
1187:
1173:
1155:
1137:
1116:
1094:
1093:
1091:
1088:
1079:
1076:
1041:
1040:
1037:
1036:
1031:
1021:
1020:
1014:
1013:
1010:
1009:
1007:
1005:
998:
997:
990:
983:
979:
978:
975:
974:
964:
963:
957:
954:
953:
949:NP_001278232.1
945:NP_001278214.1
927:
926:
920:
916:
915:
912:
911:
901:
900:
894:
891:
890:
872:
871:
865:
861:
860:
857:
856:
848:
847:
841:
838:
837:
829:
828:
822:
816:
815:
812:
811:
803:
802:
796:
793:
792:
784:
783:
777:
771:
770:
767:
766:
758:
757:
751:
748:
747:
739:
738:
732:
726:
725:
720:
715:
711:
710:
700:
699:
696:
695:
684:
683:
681:
680:
675:
670:
665:
660:
655:
650:
645:
640:
635:
630:
625:
620:
615:
610:
605:
600:
595:
590:
584:
582:
578:
577:
575:
574:
569:
564:
559:
554:
549:
543:
541:
537:
536:
534:
533:
528:
522:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
450:
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
13:
10:
9:
6:
4:
3:
2:
1931:
1920:
1917:
1915:
1912:
1911:
1909:
1898:
1893:
1891:
1886:
1884:
1879:
1878:
1872:
1870:
1866:
1862:
1858:
1853:
1850:
1846:
1841:
1830:
1827:
1826:
1824:
1822:Other/unknown
1820:
1814:
1811:
1809:
1806:
1805:
1803:
1801:
1797:
1791:
1788:
1786:
1783:
1781:
1778:
1776:
1773:
1772:
1770:
1768:
1764:
1758:
1755:
1753:
1750:
1748:
1745:
1743:
1740:
1738:
1735:
1734:
1732:
1730:
1726:
1720:
1717:
1716:
1714:
1712:
1708:
1704:
1700:
1693:
1688:
1686:
1681:
1679:
1674:
1673:
1670:
1661:
1657:
1653:
1649:
1644:
1639:
1636:(4): 801–14.
1635:
1631:
1627:
1622:
1618:
1614:
1609:
1604:
1600:
1596:
1592:
1588:
1584:
1579:
1575:
1571:
1566:
1561:
1557:
1553:
1549:
1544:
1540:
1536:
1531:
1526:
1522:
1518:
1514:
1510:
1506:
1501:
1497:
1493:
1488:
1483:
1479:
1475:
1471:
1467:
1463:
1458:
1454:
1450:
1445:
1440:
1436:
1432:
1428:
1424:
1420:
1415:
1411:
1407:
1402:
1397:
1392:
1387:
1383:
1379:
1375:
1371:
1367:
1362:
1358:
1354:
1349:
1344:
1340:
1336:
1332:
1327:
1326:
1321:
1312:
1308:
1304:
1300:
1296:
1292:
1288:
1284:
1276:
1273:
1268:
1264:
1259:
1254:
1250:
1246:
1242:
1238:
1234:
1227:
1224:
1219:
1215:
1211:
1207:
1204:(2): 307–17.
1203:
1199:
1191:
1188:
1183:
1177:
1174:
1169:
1165:
1159:
1156:
1151:
1147:
1141:
1138:
1134:
1130:
1125:
1123:
1121:
1117:
1113:
1109:
1104:
1102:
1100:
1096:
1089:
1087:
1085:
1077:
1075:
1073:
1068:
1066:
1063:
1059:
1056:(FAT4), is a
1055:
1051:
1047:
1035:
1030:
1026:
1022:
1019:
1015:
1008:
1006:
1003:
999:
995:
991:
988:
984:
980:
973:
971:
965:
961:
958:
952:
950:
946:
942:
938:
934:
928:
924:
921:
917:
910:
908:
902:
898:
895:
889:
887:
883:
879:
873:
869:
866:
864:RefSeq (mRNA)
862:
855:
854:
849:
845:
842:
836:
835:
830:
826:
823:
821:
817:
810:
809:
804:
800:
797:
791:
790:
785:
781:
778:
776:
772:
765:
764:
759:
755:
752:
746:
745:
740:
736:
733:
731:
727:
724:
721:
719:
716:
712:
709:
705:
701:
694:
690:
685:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
653:cell adhesion
651:
649:
646:
644:
641:
639:
636:
634:
631:
629:
626:
624:
621:
619:
616:
614:
611:
609:
606:
604:
601:
599:
596:
594:
591:
589:
586:
585:
583:
580:
579:
573:
570:
568:
565:
563:
560:
558:
555:
553:
550:
548:
545:
544:
542:
539:
538:
532:
529:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
433:Gonadal ridge
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
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1869:expanding it
1861:chromosome 4
1854:
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1633:
1629:
1590:
1586:
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1512:
1508:
1469:
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1426:
1422:
1376:(2): e4653.
1373:
1369:
1341:(3): 523–8.
1338:
1334:
1286:
1282:
1275:
1243:(4): 793–8.
1240:
1236:
1226:
1201:
1198:J. Mol. Biol
1197:
1190:
1176:
1167:
1158:
1149:
1140:
1081:
1069:
1061:
1053:
1052:(CDHF14) or
1049:
1045:
1044:
967:
937:NP_001278232
933:NP_001278214
930:
904:
882:NM_001291303
878:NM_001291285
875:
851:
832:
806:
787:
761:
742:
722:
717:
603:neurogenesis
441:vas deferens
333:
326:
191:125,492,932
178:125,314,918
53:External IDs
449:human fetus
292:39,066,134
279:38,941,089
31:Identifiers
1908:Categories
1429:(1): 2–4.
1135:, May 2017
1114:, May 2017
1090:References
337:(ortholog)
271:3|3 B
74:HomoloGene
1859:on human
970:NP_899044
941:NP_078858
907:NM_183221
886:NM_024582
708:Orthologs
82:GeneCards
1711:Receptor
1660:13709685
1652:16713569
1617:19414484
1574:15345747
1539:20379614
1509:Mol. Med
1496:19734545
1453:20351715
1410:19247474
1370:PLOS ONE
1357:16865240
1311:14414158
1303:24913602
1267:19048595
1218:15003449
1131:–
1110:–
1018:Wikidata
687:Sources:
557:membrane
1757:MOBKL1B
1752:MOBKL1A
1608:2701336
1530:2896464
1487:2773267
1444:3883627
1401:2644817
1378:Bibcode
1258:2667156
1133:Ensembl
1112:Ensembl
1058:protein
820:UniProt
775:Ensembl
714:Species
693:QuickGO
457:condyle
312:pattern
70:3045256
38:Aliases
1829:RASSF1
1767:Kinase
1658:
1650:
1615:
1605:
1572:
1537:
1527:
1494:
1484:
1451:
1441:
1408:
1398:
1355:
1309:
1301:
1265:
1255:
1216:
1004:search
1002:PubMed
853:Q2PZL6
834:Q6V0I7
763:329628
730:Entrez
483:BioGPS
437:dermis
170:4q28.1
62:612411
1863:is a
1785:LATS2
1780:LATS1
1742:FRMD6
1656:S2CID
1307:S2CID
744:79633
723:Mouse
718:Human
689:Amigo
395:tibia
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
78:14377
1865:stub
1857:gene
1808:YAP1
1790:STK3
1775:MST1
1747:SAV1
1719:FAT4
1648:PMID
1630:Cell
1613:PMID
1570:PMID
1535:PMID
1492:PMID
1449:PMID
1406:PMID
1353:PMID
1299:PMID
1263:PMID
1214:PMID
1065:gene
1062:FAT4
421:hand
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
86:FAT4
58:OMIM
45:FAT4
22:FAT4
1813:TAZ
1737:NF2
1638:doi
1634:125
1603:PMC
1595:doi
1560:doi
1525:PMC
1517:doi
1482:PMC
1474:doi
1439:PMC
1431:doi
1396:PMC
1386:doi
1343:doi
1291:doi
1287:133
1253:PMC
1245:doi
1241:124
1206:doi
1202:337
491:n/a
288:End
187:End
90:OMA
66:MGI
1910::
1701::
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1591:18
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1427:16
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1200:.
1166:.
1148:.
1119:^
1098:^
1086:.
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1067:.
691:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
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68::
64:;
60::
1896:e
1889:t
1882:v
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1691:e
1684:t
1677:v
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1556:3
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109:)
92::
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