1584:
2013:
40:
451:. Adipose tissue gives "mechanical cushioning" to the body, among other functions. Although there is no dense collagen network in adipose tissue, groups of adipose cells are kept together by collagen fibers and collagen sheets in order to keep fat tissue under compression in place (for example, the sole of the foot). Both the ground substance and proteins (fibers) create the matrix for connective tissue.
2467:
541:
2479:
282:.) Loose and dense connective tissue are distinguished by the ratio of ground substance to fibrous tissue. Loose connective tissue has much more ground substance and a relative lack of fibrous tissue, while the reverse is true of dense connective tissue. Dense regular connective tissue, found in structures such as
294:
fibers arranged in an orderly parallel fashion, giving it tensile strength in one direction. Dense irregular connective tissue provides strength in multiple directions by its dense bundles of fibers arranged in all directions.
895:
1598:
Betts, J Gordon; Desaix, Peter; Johnson, Eddie; Johnson, Jody E; Korol, Oksana; Kruse, Dean; Poe, Brandon; Wise, James; Womble, Mark D; Young, Kelly A (26 June 2023).
572:
to cells, and carbon dioxide and waste substances to diffuse from cells back into circulation. They also allow organs to resist stretching and tearing forces.
80:
2054:
1676:
869:
Biga, Lindsay M.; Dawson, Sierra; Harwell, Amy; Hopkins, Robin; Kaufmann, Joel; LeMaster, Mike; Matern, Philip; Morrison-Graham, Katie; Quick, Devon (2019),
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236:
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604:, also provide resistance to stretch forces. They are found in the walls of large blood vessels and in certain ligaments, particularly in the
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Connective tissue has a wide variety of functions that depend on the types of cells and the different classes of fibers involved.
2047:
1669:
870:
2368:
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573:
275:
1472:"Mapping the Ligand-binding Sites and Disease-associated Mutations on the Most Abundant Protein in the Human, Type I Collagen"
1375:
664:
Various types of specialized tissues and cells are classified under the spectrum of connective tissue, and are as diverse as
457:
is present in many forms of connective tissue, and makes up about 25% of the total protein content of the mammalian body.
75:
2457:
782:
1138:
2316:
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261:
1335:"Collagen fibers, reticular fibers and elastic fibers. A comprehensive understanding from a morphological viewpoint"
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2016:
1254:
730:
1308:
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721:
649:
into all types of mature connective tissue. Another type of relatively undifferentiated connective tissue is the
443:
allowing fixation of
Collagen fibers in intercellular spaces. Examples of non-fibrous connective tissue include
2407:
2299:
938:
Aterman, K. (1981). "Connective tissue: An eclectic historical review with particular reference to the liver".
646:
63:
661:. This tissue is no longer present after birth, leaving only scattered mesenchymal cells throughout the body.
212:
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Connective tissue can be broadly classified into connective tissue proper, and special connective tissue.
87:
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154:, are composed of connective tissue. Most types of connective tissue consists of three main components:
178:
are classed as specialized fluid connective tissues that do not contain fiber. All are immersed in the
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tendon, ligament, skin, cornea, cartilage, bone, blood vessels, gut, and intervertebral disc.
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138:. Connective tissue is found in between other tissues everywhere in the body, including the
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334:. New vascularised connective tissue that forms in the process of wound healing is termed
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568:, have an important role in providing a medium for oxygen and nutrients to diffuse from
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700:—are found scattered in loose connective tissue, providing the ground for starting
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338:. All of the special connective tissue types have been included as a subset of
39:
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1984:
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215:. The tissue was already recognized as a distinct class in the 18th century.
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1255:"Supporting Connective Tissue | Human Anatomy and Physiology Lab (BSB 141)"
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US National
Institute of Arthritis and Musculoskeletal and Skin Diseases
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951:
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709:
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576:, which forms organized structures, is a major functional component of
1602:. Houston: OpenStax CNX. 4.3 Connective Tissue supports and protects.
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1816:
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1222:
788:
642:
589:
577:
339:
283:
132:
2032:
840:
Biga, Lindsay M.; Dawson, Sierra; Harwell, Amy (26 September 2019).
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are epithelial with an underlying layer of loose connective tissue.
93:
2440:
1850:
1845:
1829:
673:
539:
448:
388:
322:. Other kinds of connective tissues include fibrous, elastic, and
319:
315:
175:
171:
147:
2435:
2250:
2087:
1887:
1376:"Monitoring Tissue Engineering Using Magnetic Resonance Imaging"
1006:
681:
326:
connective tissues. Fibroareolar tissue is a mix of fibrous and
311:
2036:
1658:
1423:"Metabolic syndrome pathophysiology: The role of adiposetissue"
726:
There are many types of connective tissue disorders, such as:
641:
is a type of connective tissue found in developing organs of
588:, and is also found in highly specialized organs such as the
1532:(6th ed.). Lippincott Williams & Wilkins. pp.
1171:
Bordoni, Bruno; Mahabadi, Navid; Varacallo, Matthew (2022).
1207:"Fascial nomenclature: Update on related consensus process"
635:(that is, the bulk of functional substance) of the organ.
330:. Fibromuscular tissue is made up of fibrous tissue and
1559:
Wheater's
Functional Histology: A Text and Colour Atlas
785:(SLE) – a major autoimmune disease of connective tissue
922:
Connective Tissue, Macromolecular
Structure Evolution.
805:
that leads to an abnormal growth in the arterial wall.
2455:
1281:"Fluid or liquid connective tissue: blood and lymph"
1003:
Carol
Mattson Porth; Glenn Matfin (1 October 2010).
435:
is a clear, colorless, and viscous fluid containing
2422:
2421:
2398:
2342:
2307:
2298:
2291:
2209:
2191:
2180:
2153:
2112:
2103:
2096:
2070:
1725:
1692:
1205:Schleip, R; Hedley, G; Yucesoy, CA (October 2019).
1009:. Lippincott Williams & Wilkins. pp. 24–.
74:
62:
57:
32:
48:. Connective tissue (blue) is seen supporting the
2399:
1427:Nutrition, Metabolism and Cardiovascular Diseases
795:which is necessary for the synthesis of collagen.
765:– a pathological weakening of connective tissue.
353:Bone and cartilage can be further classified as
501:Allow organs like arteries and lungs to recoil
2048:
1670:
871:"4.3 Connective Tissue Supports and Protects"
360:. Blood and lymph can also be categorized as
8:
206:
1639:Connective tissue atlas, University of Iowa
2304:
2295:
2188:
2109:
2100:
2055:
2041:
2033:
1677:
1663:
1655:
1166:
1164:
777:undifferentiated connective tissue disease
485:Bind bones and other tissues to each other
383:. Connective tissue membranes include the
38:
1487:
1446:
1350:
1230:
523:liver, bone marrow, and lymphatic organs
205:The term "connective tissue" (in German,
182:. The cells of connective tissue include
1644:Heritable disorders of connective tissue
1380:Journal of Bioscience and Bioengineering
459:
2462:
1519:
1517:
1515:
1513:
1511:
1509:
1507:
1303:
1301:
832:
743:malignant peripheral nerve sheath tumor
222:
1561:(6th ed.). Elsevier. p. 65.
1557:Young B, Woodford P, O'Dowd G (2013).
924:Springer-Verlag, Berlin and New York.
864:
862:
860:
858:
379:can be either of connective tissue or
91:
29:
684:. Cells of the immune system—such as
7:
1421:Laclaustra, M.; et al. (2007).
1114:"Medical Definition of FIBROAREOLAR"
107:is one of the four primary types of
27:Type of biological tissue in animals
1650:Connective tissue photomicrographs
1339:Archives of Histology and Cytology
1279:Karki, Gaurab (23 February 2018).
877:, OpenStax/Oregon State University
546:inherited connective tissue defect
517:Form a scaffolding for other cells
387:(the three membranes covering the
346:, with blood and lymph classed as
280:dense irregular connective tissues
25:
2352:Dense irregular connective tissue
558:dense irregular connective tissue
536:Epithelial-mesenchymal transition
2477:
2465:
2012:
2011:
1587: This article incorporates
1582:
708:responses upon the detection of
544:Hypermobility as a result of an
234:
225:
2369:Dense regular connective tissue
1476:Journal of Biological Chemistry
1139:"Granulation Tissue Definition"
769:Mixed connective tissue disease
631:—or structural support—for the
574:Dense regular connective tissue
504:Elastic microfibril and elastin
1627:Overview, University of Kansas
123:. It develops mostly from the
1:
146:, membranes that envelop the
1439:10.1016/j.numecd.2006.10.005
1374:Xu, H.; et al. (2008).
803:disease of the blood vessels
791:, caused by a deficiency of
783:Systemic lupus erythematosus
211:) was introduced in 1830 by
1528:Histology: A Text and Atlas
1309:"Membranes | SEER Training"
731:Connective tissue neoplasms
262:reticular connective tissue
2518:
1524:Ross M, Pawlina W (2011).
719:
533:
399:that line joint cavities.
2007:
1259:courses.lumenlearning.com
1179:. StatPearls Publishing.
940:The Histochemical Journal
722:Connective tissue disease
415:Fiber types found in the
304:Special connective tissue
299:Special connective tissue
86:
37:
18:Fibrous connective tissue
1632:26 December 2010 at the
1600:Anatomy & Physiology
1470:Di Lullo; G. A. (2002).
1313:training.seer.cancer.gov
1039:"The Connective Tissues"
875:Anatomy & Physiology
651:mucous connective tissue
488:Alpha polypeptide chains
252:Connective tissue proper
247:Connective tissue proper
1333:Ushiki, T (June 2002).
920:Mathews, M. B. (1975).
799:Fibromuscular dysplasia
763:Myxomatous degeneration
362:fluid connective tissue
271:dense connective tissue
257:loose connective tissue
1489:10.1074/jbc.M110709200
896:"5.3.4: Fluid Tissues"
842:"4.1 Types of Tissues"
757:Ehlers-Danlos Syndrome
549:
290:, is characterized by
207:
88:Anatomical terminology
716:Clinical significance
543:
507:extracellular matrix
213:Johannes Peter Müller
1591:available under the
1285:Online Biology Notes
983:"Connective Tissues"
827:Notes and references
670:white adipose tissue
417:extracellular matrix
1924:Meristematic tissue
1392:10.1263/jbb.106.515
1352:10.1679/aohc.65.109
1149:on 16 November 2018
1066:"Connective Tisues"
771:– a disease of the
749:Congenital diseases
657:, found inside the
645:that is capable of
560:, formed mainly by
462:
127:, derived from the
1686:Biological tissues
1045:on 31 October 2012
981:Shostak, Stanley.
952:10.1007/BF01005055
900:Biology LibreTexts
745:in nervous tissue.
739:hemangiopericytoma
550:
460:
437:glycosaminoglycans
397:synovial membranes
336:granulation tissue
2502:Connective tissue
2453:
2452:
2449:
2448:
2394:
2393:
2287:
2286:
2283:
2282:
2176:
2175:
2064:Connective tissue
2030:
2029:
1817:Phloem parenchyma
1609:978-1-947172-04-3
1173:"Anatomy, Fascia"
1093:"Histology Intro"
1072:on 6 January 2013
773:autoimmune system
527:
526:
520:Type III collagen
381:epithelial tissue
358:connective tissue
274:(subdivided into
113:epithelial tissue
105:Connective tissue
102:
101:
97:
33:Connective tissue
16:(Redirected from
2509:
2482:
2481:
2480:
2470:
2469:
2461:
2305:
2296:
2224:Reticular fibers
2193:Ground substance
2189:
2110:
2101:
2057:
2050:
2043:
2034:
2015:
2014:
1965:Vascular cambium
1851:Xylem parenchyma
1679:
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1223:10.1002/ca.23423
1211:Clinical Anatomy
1202:
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1145:. Archived from
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1104:
1103:
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1099:
1088:
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1068:. Archived from
1064:Caceci, Thomas.
1061:
1055:
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1041:. Archived from
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621:reticular fibers
513:Reticular fibers
463:
461:Types of fibers
433:Ground substance
429:reticular fibers
405:serous membranes
401:Mucous membranes
238:
229:
210:
164:ground substance
94:edit on Wikidata
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2155:Wandering cells
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2003:
1936:Ground meristem
1795:Vascular tissue
1766:Subsidiary cell
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1634:Wayback Machine
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753:Marfan syndrome
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655:Wharton's jelly
647:differentiation
625:reticular cells
606:ligamenta flava
566:collagen fibers
538:
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481:Collagen fibers
455:Type I collagen
421:collagen fibers
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332:muscular tissue
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1568:978-0702047473
1567:
1549:
1543:978-0781772006
1542:
1503:
1482:(6): 4223–31.
1462:
1433:(2): 125–139.
1413:
1386:(6): 515–527.
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1217:(7): 929–933.
1197:
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1083:
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1037:Potter, Hugh.
1029:
1016:978-1582557243
1015:
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973:
946:(3): 341–396.
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659:umbilical cord
594:Elastic fibers
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497:Elastic fibers
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445:adipose tissue
425:elastic fibers
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344:fascial system
328:areolar tissue
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266:adipose tissue
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140:nervous system
121:nervous tissue
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1861:Ground tissue
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902:. 21 May 2021
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613:hematopoietic
609:
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441:proteoglycans
438:
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411:Fibrous types
410:
408:
406:
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394:
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371:
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366:liquid fascia
363:
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145:
141:
137:
134:
131:, the middle
130:
126:
122:
118:
117:muscle tissue
114:
111:, along with
110:
109:animal tissue
106:
95:
89:
85:
82:
79:
77:
73:
70:
67:
65:
61:
56:
51:
47:
41:
36:
31:
19:
2489:
2201:Tissue fluid
2063:
1996:
1977:
1973:
1960:Cork cambium
1952:
1928:
1922:
1903:Sclerenchyma
1901:
1894:
1878:Chlorenchyma
1865:
1859:
1828:
1812:Phloem fiber
1799:
1793:
1772:
1738:
1734:
1701:
1599:
1581:
1577:
1558:
1552:
1527:
1479:
1475:
1465:
1430:
1426:
1416:
1383:
1379:
1369:
1342:
1338:
1328:
1316:. Retrieved
1312:
1288:. Retrieved
1284:
1274:
1262:. Retrieved
1258:
1249:
1214:
1210:
1200:
1188:. Retrieved
1176:
1151:. Retrieved
1147:the original
1142:
1133:
1121:. Retrieved
1117:
1108:
1096:. Retrieved
1086:
1074:. Retrieved
1070:the original
1059:
1047:. Retrieved
1043:the original
1032:
1020:. Retrieved
1005:
998:
986:. Retrieved
976:
943:
939:
933:
921:
916:
904:. Retrieved
899:
890:
879:, retrieved
874:
845:. Retrieved
835:
725:
702:inflammatory
694:plasma cells
663:
650:
637:
627:provide the
610:
596:, made from
551:
453:
414:
375:
365:
361:
357:
354:
352:
347:
343:
306:consists of
303:
302:
269:
255:
254:consists of
251:
250:
242:
204:
142:. The three
104:
103:
2423:Specialized
2413:Mesenchymal
2384:Aponeurosis
2135:Tendon cell
2097:Composition
2078:Soft tissue
1896:Collenchyma
1846:Xylem fiber
821:Parametrium
816:Endometrium
698:eosinophils
686:macrophages
586:aponeuroses
570:capillaries
562:fibroblasts
393:spinal cord
260:(including
208:Bindegewebe
192:macrophages
184:fibroblasts
152:spinal cord
58:Identifiers
44:Section of
2168:Macrophage
2145:Melanocyte
2120:Fibroblast
2071:Physiology
1985:Endodermis
1941:Procambium
1873:Aerenchyma
1867:Parenchyma
1822:Sieve tube
1785:Phelloderm
1756:Guard cell
1707:Epithelial
1702:Connective
1177:StatPearls
1123:11 October
1098:9 December
1076:9 December
1049:9 December
988:9 December
733:including
690:mast cells
639:Mesenchyme
633:parenchyma
534:See also:
472:Components
447:(fat) and
355:supportive
200:leukocytes
196:mast cells
188:adipocytes
180:body water
136:germ layer
125:mesenchyme
50:epithelium
46:epididymis
2431:Cartilage
2400:Embryonic
2357:Submucosa
2317:Reticular
2246:Fibrillin
2163:Mast cell
2140:Adipocyte
2125:Fibrocyte
2022:Histology
1990:Exodermis
1954:Secondary
1946:Protoderm
1883:Mesophyll
1740:Epidermis
1593:CC BY 4.0
793:vitamin C
678:cartilage
653:known as
619:tissues,
617:lymphatic
602:fibrillin
582:ligaments
475:Location
377:Membranes
372:Membranes
308:cartilage
288:ligaments
133:embryonic
2496:Category
2484:Medicine
2374:Ligament
2113:Resident
2088:Scarring
2083:Fibrosis
2017:Category
1914:Sclereid
1836:Tracheid
1774:Periderm
1712:Muscular
1630:Archived
1595:license.
1498:11704682
1457:17270403
1400:19134545
1361:12164335
1318:3 August
1290:16 April
1264:16 April
1241:31183880
1190:3 August
1185:29630284
968:22765625
906:2 August
881:16 April
810:See also
751:include
737:such as
735:sarcomas
710:antigens
623:made by
530:Function
385:meninges
324:lymphoid
292:collagen
144:meninges
129:mesoderm
52:(purple)
2472:Biology
2458:Portals
2322:Adipose
2273:Elaunin
2268:EMILIN1
2241:Elastin
1930:Primary
1780:Phellem
1751:Cuticle
1717:Nervous
1694:Animals
1448:4426988
1408:3294995
1232:6852276
1143:Memidex
960:7019165
847:30 July
775:, also
643:embryos
598:elastin
578:tendons
469:Purpose
342:in the
284:tendons
156:elastic
69:D003238
2408:Mucoid
2379:Tendon
2362:Dermis
2300:Proper
2229:COL3A1
2211:Fibers
2184:matrix
1979:Cortex
1801:Phloem
1727:Plants
1606:
1565:
1540:
1496:
1455:
1445:
1406:
1398:
1359:
1239:
1229:
1183:
1022:11 May
1013:
966:
958:
789:Scurvy
706:immune
696:, and
629:stroma
590:cornea
466:Tissue
427:, and
395:) and
364:, and
340:fascia
268:) and
174:, and
166:, and
119:, and
2441:Blood
2344:Dense
2332:White
2327:Brown
2309:Loose
2292:Types
2105:Cells
1998:Stele
1974:Mixed
1909:Fiber
1830:Xylem
1536:–97.
1404:S2CID
1153:7 May
964:S2CID
801:is a
674:blood
666:brown
554:Loose
449:blood
389:brain
320:lymph
316:blood
219:Types
176:lymph
172:Blood
168:cells
148:brain
92:[
81:96404
2436:Bone
2261:FBN3
2256:FBN2
2251:FBN1
1888:Pith
1604:ISBN
1589:text
1563:ISBN
1538:ISBN
1494:PMID
1453:PMID
1396:PMID
1357:PMID
1320:2022
1292:2021
1266:2021
1237:PMID
1192:2022
1181:PMID
1155:2016
1125:2018
1100:2012
1078:2012
1051:2012
1024:2011
1011:ISBN
990:2012
956:PMID
926:link
908:2022
883:2021
849:2022
755:and
741:and
704:and
682:bone
680:and
668:and
615:and
600:and
584:and
564:and
556:and
439:and
419:are
403:and
391:and
318:and
312:bone
286:and
278:and
264:and
198:and
158:and
150:and
64:MeSH
1534:158
1484:doi
1480:277
1443:PMC
1435:doi
1388:doi
1384:106
1347:doi
1227:PMC
1219:doi
948:doi
611:In
76:FMA
2498::
1976::
1927::
1864::
1798::
1737::
1506:^
1492:.
1478:.
1474:.
1451:.
1441:.
1431:17
1429:.
1425:.
1402:.
1394:.
1382:.
1378:.
1355:.
1343:65
1341:.
1337:.
1311:.
1300:^
1283:.
1257:.
1235:.
1225:.
1215:32
1213:.
1209:.
1175:.
1163:^
1141:.
1116:.
962:.
954:.
944:13
942:.
898:.
873:,
857:^
712:.
692:,
688:,
676:,
672:,
608:.
592:.
580:,
431:.
423:,
368:.
350:.
314:,
310:,
202:.
194:,
190:,
186:,
170:.
162:,
115:,
2460::
2056:e
2049:t
2042:v
1678:e
1671:t
1664:v
1612:.
1571:.
1546:.
1500:.
1486::
1459:.
1437::
1410:.
1390::
1363:.
1349::
1322:.
1294:.
1268:.
1243:.
1221::
1194:.
1157:.
1127:.
1102:.
1080:.
1053:.
1026:.
992:.
970:.
950::
928:.
910:.
851:.
779:.
759:.
548:.
96:]
20:)
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