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F protein interacts with a fraction of M at the level of the ER membranes. This F-M protein complex is transported to the plasma membrane. At the cell surface, F-M defines a nucleation site for more M condensation (a fraction of M positioned at cell membrane without F interaction) and for HN
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Mutation of the TYTLE Motif in the
Cytoplasmic Tail of the Sendai Virus Fusion Protein Deeply Affects Viral Assembly and Particle Production Plos one, Published: December 10, 2013https://doi.org/10.1371/journal.pone.0078074
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recruitment (likely through M). Nucleocapsids (not shown) may now bind to a stable assembly complex made of the 3 membrane viral proteins leading to virus particle budding.
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078074
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https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078074
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Manel
Essaidi-Laziosi,Anastasia Shevtsova,Denis Gerlier,Laurent Roux
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Possible model depicting formation of the viral assembly complex.
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