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gp41 undergoes significant conformational change; folding in half and forming coiled-coils. This process pulls the viral and cellular membranes together, fusing them.
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decorated the interior of the virion and capitalised CCR5 and made gp41 coil as a bundle as opposed to scissoring
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Conformational change in gp120 allows for secondary interaction with CXCR4.
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
