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523:{{Information |Description=Schematic diagram of the mechanism of action of {{w|ivermectin}} on the invertebrate glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel. Ivermectin (IVM) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits, "locking" the receptor in an activated (open) conformation that allows unrestricted passage of chloride (Cl<sup>−</sup>) ions into the cell. The plasma membrane is represented as a...
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on the invertebrate glutamate-gated chloride channel receptor (GluClR), a pentameric ligand-gated ion channel. Ivermectin (IVM) interacts with a binding pocket formed by the transmembrane domains of adjacent GluClR subunits, "locking" the receptor in an activated (open) conformation that allows
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Représentation schématique du mécanisme d'action de l'ivermectine sur le récepteur du "canal chlorure glutamate-dépendant" chez les invertébrés (GluClR ; un canal ionique pentamérique ligand-dépendant). L'ivermectine (IVM) interagit avec une poche de liaison formée par les domaines
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transmembranaires des sous-unités GluClR adjacentes, "bloquant" le récepteur dans une conformation activée (ouverte) permettant le passage sans restriction des ions chlorure (Cl-) dans la cellule. La membrane plasmique est représentée par un gradient bleu-rose.
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unrestricted passage of chloride (Cl) ions into the cell. The plasma membrane is represented as a blue–pink gradient.
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556:Ivermectine
145:Description
596:Ivermektin
576:Ivermektin
566:Իվերմեկտին
538:Ivermectin
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